Parasite最新文献

{"title":"News from the forest of Mondulkiri: additions to the mosquito fauna of Cambodia (Diptera: Culicidae).","authors":"Pierre-Olivier Maquart, Kimhuor Suor, Amélie Vantaux, Bros Doeurk, Kalyan Chhoy, Kimly Heng, Saoya Sen, Rina Chea, Kimsear Nov, Theary Keum, Sokkeang Leng, Sébastien Boyer","doi":"10.1051/parasite/2025064","DOIUrl":"10.1051/parasite/2025064","url":null,"abstract":"<p><p>Following the ongoing inventory efforts conducted in Cambodia by the Medical and Veterinary Unit of the Institut Pasteur du Cambodge, and after intensive collection work in the eastern part of the country, we report 20 new mosquito species from Cambodia. Among these new records, none are considered to be of medical importance. Along with these new records, and incorporating 2 recently described species, we provide an updated checklist of the Culicidae fauna of Cambodia, which now includes 312 species, 43 of which are known to be of medical importance and are involved in the transmission of pathogens.</p>","PeriodicalId":19796,"journal":{"name":"Parasite","volume":"32 ","pages":"75"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12674679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145669013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and genotype analysis of Cryptosporidium spp. in nine species of wild rodents in China.","authors":"Zhen-Qiu Gao, Hai-Tao Wang, Jing-Hao Li, Yi-Xuan Song, Qing-Yu Hou, Si-Yuan Qin, He Ma, Quan Zhao, Ya Qin","doi":"10.1051/parasite/2025012","DOIUrl":"10.1051/parasite/2025012","url":null,"abstract":"<p><p>Cryptosporidium is a significant zoonotic parasite with broad distribution in both humans and rodents. In this study, 510 fecal samples were collected from nine species of wild rodents across Guangxi, Yunnan, and Hunan Provinces in China. Nested PCR analysis targeting the SSU rRNA gene revealed an overall Cryptosporidium infection rate of 1.8% (9/510) among rodents in these provinces. The highest positivity rate was observed in Guangxi Province at 4.9% (5/103), followed by Yunnan Province (2.3%, 2/88), and Hunan Province (0.6%, 2/319). Notably, Rattus losea exhibited the highest prevalence rate at 9.8% (4/41), while Rattus flavipectus and Niviventer lotipes showed rates of 5.1% (2/39) and 4.4% (1/23), respectively. Various genotypes/species were identified, including Cryptosporidium viatorum, Cryptosporidium muris, Cryptosporidium vole genotype VII, and Cryptosporidium ratti, rat genotypes II, and IV. The study also found that wild rodents inhabiting mountainous areas had a higher prevalence rate at 4.9% (5/103) compared to those residing in fields and lake beaches, where prevalence rates were 2.1% (2/95) and 0.6% (2/312), respectively. This study provides new insights into Cryptosporidium infection rates among wild rodents and identifies two zoonotic species, C. viatorum and C. muris. These findings underscore the potential risk posed by Chinese wild rodent populations in transmitting zoonotic Cryptosporidium, which could significantly impact public health. Therefore, effective control strategies are needed to prevent transmission between humans and rodents.</p>","PeriodicalId":19796,"journal":{"name":"Parasite","volume":"32 ","pages":"19"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11888585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143575915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphological phylogeny on the unnatural grouping of Demidospermus-like species (Monopisthocotyla, Dactylogyridae) with the proposal of new genera, genera resurrections, and descriptions of new species.","authors":"Julio Cesar Cenci de Aguiar, Patrick D Mathews, Marcus Vinicius Domingues, Reinaldo J da Silva","doi":"10.1051/parasite/2025034","DOIUrl":"10.1051/parasite/2025034","url":null,"abstract":"<p><p>Dactylogyrids are flatworms of ecological and economic significance, parasitizing fish worldwide. In recent years, there has been a surge in the description of Neotropical dactylogyrids, particularly those infecting siluriform fishes. While these studies have contributed to the organization of some genera and refined species boundaries through integrative taxonomy, certain groups within the family, such as Demidospermus, remain taxonomically unstable. This study focuses on Demidospermus, aiming to reclassify species of uncertain status into appropriate genera and establish a morphological framework to support future evolutionary analyses and taxonomic revisions within the Demidospermus-like species group. Supported by morphological phylogenetic analysis, we propose the new genera Rhabdolachosus n. gen., Martorellius n. gen., Magnanchistrius n. gen., and Sicohencotyle n. gen., along with the resurrection of Omothecium Kritsky, Thatcher & Boeger, 1987, and Paramphocleithrium Suriano & Incorvaia, 1995. Additionally, two new species are described: Sicohencotyle antoniomaiai n. gen. n. sp. and Ameloblastella sakulocirra n. sp. Also, Demidospermus centromochi Mendoza-Franco & Scholz, 2009 is classified as sedis mutabilis, while D. annulus Marcotegui & Martorelli, 2011, D. brevicirrus Mendoza-Palmero et al., 2012, D. cornicinus Kritsky & Gutierrez, 1998, D. idolus Kritsky & Gutierrez, 1998, D. armostus Kritsky & Gutierrez, 1998, D. mortenthaleri Mendoza-Palmero et al., 2012, D. osteomystax Tavernari et al., 2010, D. tocantinensis Cohen et al., 2020, D. doncellae Morey et al., 2024, D. bifurcatus Justo, Martins & Cohen, 2024, D. juruaensis Justo, Martins & Cohen, 2024, and D. takemotoi Justo, Martins & Cohen, 2024 are considered incertae sedis. Lastly, Urocleidoides amazonensis Mizelle & Kritsky, 1969 remains classified as incertae sedis.</p>","PeriodicalId":19796,"journal":{"name":"Parasite","volume":"32 ","pages":"49"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12324567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Different patterns of Toxoplasma gondii infection epidemiology in the general population, animal contact workers, and blood donors in southeastern China between 2019 and 2023: a cross-sectional study.","authors":"Xiaoxiao Wang, Wei Ruan, Wenjie Xu, Hualiang Chen, Jiaqi Zhang, Xuan Zhang, Kegen Yu, Qiaoyi Lu, Zhen Wang, Jimin Sun","doi":"10.1051/parasite/2025061","DOIUrl":"10.1051/parasite/2025061","url":null,"abstract":"<p><p>There are estimated to be over one billion human infections of Toxoplasma gondii worldwide. However, significant spatial heterogeneity exists across countries and regions. For this study, a total of 2,943 participants were enrolled between 2019 and 2023 in Zhejiang Province, southeastern China including 519 animal contact workers, 1,722 people from the general population, and 702 blood donors. Anti-T. gondii IgG and IgM in sera were assessed using an enzyme-linked immunosorbent assay. The overall seroprevalence of IgG and IgM was 4.08% and 0.41%, respectively. IgG positivity was highest in the (50, 60] years age group (5.47%, 29/530), while IgM was found in the (60, 70] years age group (1.21%, 3/247). The general population showed the lowest IgG seroprevalence (1.68%) compared to animal contact workers (10.40%) and blood donors (5.27%) (p < 0.001). Patterns of T. gondii IgG prevalence varied by participant type. Increasing seroprevalence with age was observed among animal contact workers, indicating a cumulative effect, while frequency was highest in the (50, 60] and (30, 40] age groups in the general population and blood donors, respectively. Animal contact workers with two types of animal exposure had higher IgG positivity rates (13.16%) than those with one type (8.50%). Occupational exposure to cattle was associated with the highest frequency of IgG (12.69%), followed by pigs (9.69%), and sheep (8.85%). This study provides critical insights into the epidemiological characteristics of T. gondii infections across distinct population groups in Eastern China.</p>","PeriodicalId":19796,"journal":{"name":"Parasite","volume":"32 ","pages":"68"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12543297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145346635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular analysis of DHFR and DHPS gene mutations in Plasmodium cynomolgi from humans and macaques in Southeast Asia.","authors":"Raweewan Sangsri, Nathjanan Jongkon, Kiattawee Choowongkomon, Suchinda Malaivijitnond, Nicholas P J Day, Arjen M Dondorp, Mallika Imwong","doi":"10.1051/parasite/2025057","DOIUrl":"10.1051/parasite/2025057","url":null,"abstract":"<p><p>Plasmodium cynomolgi is an emerging zoonotic malaria parasite in Southeast Asia, infecting both humans and macaques. In this study, we investigated mutations in the DHFR and DHPS genes of P. cynomolgi from humans and macaques, comparing them to known resistance mutations in P. falciparum and P. vivax. We also examined how these mutations affect antifolate drug binding, which may influence treatment efficacy and resistance. Nine asymptomatic human blood samples from Cambodia and 29 macaque samples from Thailand were analyzed. Human samples included eight P. cynomolgi monoinfections and one mixed infection with P. vivax, while all macaque samples were monoinfections. The PcyDHFR and PcyDHPS genes were amplified, sequenced, and subjected to haplotype analysis. Human samples from Battambang, Cambodia were 100% identical to the P. cynomolgi RO strain, showing no DHFR mutations and one DHPS mutation (V451I). In contrast, macaque samples from Saraburi, Thailand showed PcyDHFR mutations N44T and C49S, and two haplotypes based on I7 variation - haplotype 1 (72.41%) with wild-type I7 and haplotype 2 (27.59%) with the I7 mutation. PcyDHPS mutations were identical across macaque isolates. Protein structures of PcyDHFR and PcyDHPS were modeled using SWISS-MODEL, focusing on the N- and C-terminals. Mutations occurred near catalytic sites but did not significantly affect binding affinity, based on molecular docking with eight antifolate drugs. These findings suggest that current antifolate drugs remain potentially effective against P. cynomolgi, and highlight the importance of monitoring drug resistance in zoonotic malaria.</p>","PeriodicalId":19796,"journal":{"name":"Parasite","volume":"32 ","pages":"64"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diversity of haemosporidian parasites in cranes: description of Haemoproteus balearicae and its phylogenetic position within the H. antigonis clade.","authors":"Mamohale Chaisi, Ndzalama Mabunda, Delphine Gey, Nkitseng Oageng Modise, Marli de Bruyn, Alexis Lécu, Sylvie Laidebeure, Anaïs Saillier, Milan Thorel, Tatjana Iezhova, Gediminas Valkiūnas, Monica Mwale, Linda Duval","doi":"10.1051/parasite/2025059","DOIUrl":"10.1051/parasite/2025059","url":null,"abstract":"<p><p>Haemosporidian parasites from the genera Haemoproteus, Plasmodium, and Leucocytozoon are significant avian pathogens. This study aimed to identify and characterize these parasites in cranes (family Gruidae), using combined morphological and molecular methods. The results confirmed the presence of Haemoproteus balearicae, redescribed here from Balearica regulorum and associated with cytb lineage hBAREGI210. This lineage, previously assigned to Haemoproteus antigonis, is reassigned to H. balearicae, suggesting possible cryptic speciation within the H. antigonis complex. The findings broaden the known host range and geographic distribution of H. balearicae, detected in captive-born cranes in France and captive cranes housed in conservation facilities in South Africa. Phylogenetic analyses revealed three distinct Haemoproteus clades in Gruidae, corresponding to at least three species, including H. balearicae and lineages representing H. antigonis. These crane-specific parasites may require taxonomic revision as a separate subgenus or genus, pending further studies on their life cycles and vectors. Additionally, several novel cytb lineages of Plasmodium and Leucocytozoon were detected, many unassigned to morphospecies. Notably, the pCATUS05 lineage, a member of the Plasmodium lutzi group previously reported only in the Americas, was detected for the first time in South African cranes, along with Leucocytozoon aff. californicus (lCIAE02), a widespread lineage lacking morphological description. Together, these findings reveal underestimated genetic diversity of haemosporidian parasites in cranes and highlight the importance of combining morphological and molecular data to clarify parasite taxonomy and host associations. This study advances our understanding of avian parasite ecology and systematics, with implications for crane conservation and disease management.</p>","PeriodicalId":19796,"journal":{"name":"Parasite","volume":"32 ","pages":"66"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12520626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145293253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and genetic diversity of Pentatrichomonas hominis in pig populations in Guangdong and Anhui Provinces, China.","authors":"Pengyun Lu, Yibin Zhu, Haiming Cai, Hanqin Shen, Siyun Fang, Dingai Wang, Zhuanqiang Yan, Shenquan Liao, Nanshan Qi, Minna Lv, Xuhui Lin, Yongle Song, Xiangjie Chen, Jianfei Zhang, Juan Li, Mingfei Sun","doi":"10.1051/parasite/2025027","DOIUrl":"10.1051/parasite/2025027","url":null,"abstract":"<p><p>Pentatrichomonas hominis is a protozoan parasite that infects the gastrointestinal tract of humans and mammals, causing abdominal pain and diarrhea. However, its presence in pigs and its potential as a pathogen causing diarrhea in piglets have not been well studied. This study aimed to investigate the prevalence of P. hominis in pigs and its potential for zoonotic transmission. A total of 406 pig fecal samples were collected from four pig farms located in Guangdong and Anhui Provinces. Fecal DNA extraction was carried out using a commercially available kit. A nested PCR methodology was employed to detect the presence of P. hominis infection. Samples that tested positive were subsequently subjected to sequencing, and the genetic characteristics of the 18S ribosomal RNA (rRNA) gene were analyzed. The overall infection rate of P. hominis was 34.98% (142/406), in Guangdong Province 28.47% (80/281), and in Anhui Province 49.60% (62/125). Among different age groups, suckling piglets had the highest infection rate at 40.24% (68/169). Genetic analysis of the P. hominis isolates showed that the PH-1 genotype was predominant and had a high degree of similarity to P. hominis sequences obtained from humans, cats, and pigs, indicating the potential for zoonotic transmission. The high infection rate and genetic diversity highlight the need for effective control measures in pig farming to reduce parasite transmission and zoonotic risk.</p>","PeriodicalId":19796,"journal":{"name":"Parasite","volume":"32 ","pages":"33"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for the ciliate Buxtonella sulcata in free-ranging dairy cattle on Terceira Island, Azores archipelago.","authors":"Mário Ribeiro, Sara Gomes-Gonçalves, Alexandra Silva, Guilherme Moreira, Eric Viscogliosi, Magali Chabé, João Rodrigo Mesquita","doi":"10.1051/parasite/2025014","DOIUrl":"10.1051/parasite/2025014","url":null,"abstract":"<p><p>Buxtonella sulcata is an alveolate ciliate protist, historically considered a commensal of the gastrointestinal tract of cattle. Despite the fact that its cysts are morphologically identical to those of Balantioides coli, molecular identification techniques have shed new light on its role as a pathogen. This work aimed to assess the presence of this ciliate in the population of dairy cattle on the Azorean island of Terceira by means of molecular analyses (ITS1-5.8S-ITS2 rRNA) of stool samples. A total of 116 samples were collected from adult Holstein-Friesian dairy cows, with no signs of gastrointestinal disease. A proportion of 49.1% of the samples were PCR-positive for Bu. sulcata, and 12 different genetic sequences were identified. These findings highlight the need for future research concerning the factors that influence the presence of Bu. sulcata in the gastrointestinal tract of dairy cows, the role of bovines as possible sources of infection, and the impact this ciliate may have on the health, welfare, and productivity of these animals.</p>","PeriodicalId":19796,"journal":{"name":"Parasite","volume":"32 ","pages":"21"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951862/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatial distribution of Ixodes ricinus in forest habitats: a comparative study of the northern and southern slopes of Mount Slavnik, Slovenia.","authors":"Jure Jugovic, Alenka Babič, Anka Kuhelj, Vladimir Ivović","doi":"10.1051/parasite/2025044","DOIUrl":"10.1051/parasite/2025044","url":null,"abstract":"<p><p>While previous studies have examined the elevational limits of Ixodes ricinus in Central Europe, this study is the first to investigate the influence of slope orientation on tick distribution in Slovenia. Our results provide new insights into how two important microclimatic factors, temperature and humidity, vary between the northern and southern slopes, and how these differences affect the abundance of I. ricinus, a factor that has not been studied in this region before. We found that nymph density was highest on the southern slope at intermediate elevations (720 m) and increased with temperature. In contrast, fewer adult ticks were found on the southern slope compared to the northern slope, most of them at 720 m elevations. The significantly higher abundance of adult ticks on the northern slope is probably related to the cooler temperatures, higher relative humidity, denser ground vegetation and greater availability of hosts such as roe deer. Although these results are regionally specific, they contribute to a more comprehensive understanding of the ecological factors influencing the distribution of I. ricinus in Central Europe.</p>","PeriodicalId":19796,"journal":{"name":"Parasite","volume":"32 ","pages":"46"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12291548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and subtype distribution of Blastocystis infections among community participants in Thailand: a systematic review and meta-analysis.","authors":"Manas Kotepui, Supaluk Popruk, Kwuntida Uthaisar Kotepui, Frederick Ramirez Masangkay, Kinley Wangdi, Aongart Mahittikorn, Christen Rune Stensvold","doi":"10.1051/parasite/2025042","DOIUrl":"10.1051/parasite/2025042","url":null,"abstract":"<p><p>A comprehensive understanding of the prevalence and subtype distribution of Blastocystis infections among community participants in Thailand is essential to inform targeted public health interventions. This systematic review and meta-analysis aimed to estimate the overall prevalence of Blastocystis infections and to determine the distribution of subtypes among community participants in Thailand. Relevant studies on Blastocystis infections in community participants in Thailand were searched in PubMed, Embase, Scopus, Ovid, ProQuest, and the Thai-Journal Citation Index. The methodological quality of the included studies was assessed using the Joanna Briggs Institute critical appraisal tools. Prevalence estimates and subtype distributions were calculated using random-effects models. A total of 947 articles were identified, with 60 studies included in the systematic review and meta-analysis. The meta-analysis led to an estimated overall prevalence of Blastocystis infections in community participants in Thailand at 8.34% (95% CI: 5.48%-12.51%; I²: 98.2%; number of studies: 60; number of participants: 33,101). Meta-regression analysis showed no significant temporal trends in infection prevalence. The highest prevalence rates were observed in Eastern Thailand (13.54%) and Western Thailand (10.09%). Subtype analysis identified ST3 and ST1 as the most common subtypes, accounting for 50.05% and 23.50% of positive samples, respectively. The highest prevalence was reported in military personnel (29.87%), followed by orphans (29.01%). Improved use of molecular and culture-based diagnostic methods is recommended to enhance detection accuracy. Public health interventions should prioritize high-risk groups, such as military personnel and orphans, and address regional disparities to reduce the burden of Blastocystis infections.</p>","PeriodicalId":19796,"journal":{"name":"Parasite","volume":"32 ","pages":"53"},"PeriodicalIF":2.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12364436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144883410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}