Otolaryngology- Head and Neck Surgery最新文献

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Prognosis of Dysphagia in Pediatric Patients With Vocal Fold Immobility. 小儿声带不动患者吞咽困难的预后。
IF 2.6 3区 医学
Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-05 DOI: 10.1002/ohn.1281
Rachel Georgopoulos, Khashayar Arianpour, Samantha Anne
{"title":"Prognosis of Dysphagia in Pediatric Patients With Vocal Fold Immobility.","authors":"Rachel Georgopoulos, Khashayar Arianpour, Samantha Anne","doi":"10.1002/ohn.1281","DOIUrl":"https://doi.org/10.1002/ohn.1281","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to determine the incidence and prognosis of dysphagia in pediatric patients with true vocal fold (TVF) immobility or hypomobility.</p><p><strong>Study design: </strong>A single-center retrospective chart review.</p><p><strong>Setting: </strong>A single-institution tertiary-care center.</p><p><strong>Methods: </strong>A total of 89 pediatric patients diagnosed with vocal fold hypo/immobility with a modified barium swallow (MBS) performed were examined. Patient demographic information and etiology of vocal fold immobility as well as laterality were reviewed. Changes in MBS findings over time were assessed.</p><p><strong>Results: </strong>A total of 89 pediatric patients were identified with a mean follow-up of 35.4 months. The most common etiology of TVF hypo/immobility was cardiothoracic surgery (58.4%).Immobility was observed in 80.6% of patients. Patients with unilateral disease were more likely to present with dysphonia than bilateral disease (40.3% vs 9.1%, odds ratio [OR] 6.75, 95% confidence interval [CI] 1.77-44.5, P = .01). MBS results did not vary statistically with respect to laterality, hypomobility versus immobility, or etiology. Of the 33 children who demonstrated aspiration on their initial MBS, 48.5% demonstrated complete resolution over median of 10.5 weeks. Rates of recovery differed only with respect to hypomobility versus immobility (87.5% vs 33.3%, OR 14.0, 95% CI 2.01-286, P = .0133).</p><p><strong>Conclusion: </strong>Based on the study results, about half of pediatric patients with vocal fold hypo/immobility will have resolution of dysphagia at about 10.5 weeks. This may helpful when deciding on when to obtain follow up imaging/exam on pediatric patients with dysphagia. The only factor that confers improved prognosis is hypomobility when compared to complete immobility.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Calvarial Osteoradionecrosis After Treatment of Cutaneous Malignancy: A Systematic Review. 皮肤恶性肿瘤治疗后颅骨放射性骨坏死的处理:一项系统综述。
IF 2.6 3区 医学
Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-05 DOI: 10.1002/ohn.1290
Siyuan Pang, Elizabeth Concannon, Martin Higgins, Katharine Drummond, Peter Gearing, Maxim Devine, Albert Tiong, Anand Ramakrishnan, Carly Fox
{"title":"Management of Calvarial Osteoradionecrosis After Treatment of Cutaneous Malignancy: A Systematic Review.","authors":"Siyuan Pang, Elizabeth Concannon, Martin Higgins, Katharine Drummond, Peter Gearing, Maxim Devine, Albert Tiong, Anand Ramakrishnan, Carly Fox","doi":"10.1002/ohn.1290","DOIUrl":"https://doi.org/10.1002/ohn.1290","url":null,"abstract":"<p><strong>Objective: </strong>Osteoradionecrosis (ORN) is a recognized complication of radiotherapy. However, calvarial ORN (ORNC) following treatment for cutaneous malignancies is poorly understood. Shedding light on the limited evidence to date, this study aims to summarize existing evidence and highlight the research gaps.</p><p><strong>Data sources: </strong>PubMed and Embase.</p><p><strong>Review methods: </strong>A systematic search of PubMed and Embase was conducted up to May 2024, using relevant keywords to identify papers on ORNC. Data on the definition, incidence, risk factors, radiotherapy parameters, diagnostic methods, and management strategies were collected.</p><p><strong>Results: </strong>Twenty articles reporting on 42 ORNC patients were identified, revealing relatively poor data quality. There remains no consensus on a definition of ORNC. Patient- and disease-related risk factors have been inconsistently documented. No conclusion could be reached regarding thresholds for radiation dose delivery, as only seven studies reported the total radiation dose, with a mean of 58.9 Gy. Twenty-five (60%) cases managed with wound care and antibiotics demonstrated a spectrum of success rates, while 90% of surgically managed ORNC wounds healed at various follow-up points, ranging from 6 weeks to 9 years.</p><p><strong>Conclusion: </strong>This study proposes an ORNC-specific definition and reporting standard through comparison with mandibular ORN. This will help generate valuable data, guiding the development of an ORNC-specific treatment protocol and clinical decision-making in managing this debilitating side effect of radiotherapy.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of Benign Paroxysmal Positional Vertigo Modified by Diuretics-A Population-Level Case-Control Study. 利尿剂改善良性阵发性位置性眩晕的风险:一项人群水平的病例对照研究
IF 2.6 3区 医学
Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-05 DOI: 10.1002/ohn.1282
Marwin Li, Rebecca C Chiffer, Hongyan Li
{"title":"Risk of Benign Paroxysmal Positional Vertigo Modified by Diuretics-A Population-Level Case-Control Study.","authors":"Marwin Li, Rebecca C Chiffer, Hongyan Li","doi":"10.1002/ohn.1282","DOIUrl":"https://doi.org/10.1002/ohn.1282","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to characterize diuretic use among patients with and without benign paroxysmal positional vertigo (BPPV) using a population-level database.</p><p><strong>Study design: </strong>A case-control study.</p><p><strong>Setting: </strong>TriNetX US Collaborative Network.</p><p><strong>Methods: </strong>Subjects with ≥1 hospital visit between 2019 and 2024 were queried and stratified by age (18-44, 45-64, and 65+ years) and sex. Each cohort was then divided into those with/without BPPV. Patients with head trauma, middle/inner ear surgery, central vertigo, or migraine were excluded. The prevalence of diuretic use and vitamin D deficiency of each case cohort was compared against the control cohort of the same age/sex using Chi-square analysis. This stratification and analysis were repeated for patients with a vestibular disorder, as well as those with/without Ménière's disease (MD).</p><p><strong>Results: </strong>Diuretic use was significantly more common in case cohorts than in control cohorts in the general population. In vestibular patients, thiazide and carbonic anhydrase inhibitor (CAI) use were more common in control cohorts, and loop use was less common. In MD patients, thiazide and loop use were more common in control cohorts, and CAI use did not differ significantly. In patients without MD, CAI use also did not differ, while thiazide and loop use were less common in control cohorts.</p><p><strong>Conclusion: </strong>All diuretics may alter the risk of BPPV. Their influences can be favorable or unfavorable, depending on the individual patient's medical history. Their effects might relate more directly to the efficacy of each diuretic class rather than their specific mechanisms of action.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
N-acetylcysteine for the Prevention of Cisplatin-Induced Hearing Loss: A Systematic Review and Meta-analysis. n-乙酰半胱氨酸预防顺铂性听力损失:系统综述和荟萃分析
IF 2.6 3区 医学
Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-05 DOI: 10.1002/ohn.1272
Jaime Plane, Thamiris D D Cabral, Renata M Knoll, João E P Conrado, Bruno D V Vendramini, David H Jung
{"title":"N-acetylcysteine for the Prevention of Cisplatin-Induced Hearing Loss: A Systematic Review and Meta-analysis.","authors":"Jaime Plane, Thamiris D D Cabral, Renata M Knoll, João E P Conrado, Bruno D V Vendramini, David H Jung","doi":"10.1002/ohn.1272","DOIUrl":"https://doi.org/10.1002/ohn.1272","url":null,"abstract":"<p><strong>Objective: </strong>Cisplatin is an effective antineoplastic drug used worldwide in the treatment of various malignancies. However, it is associated with side effects, including cisplatin-induced hearing loss (CIHL). N-acetylcysteine (NAC) has been suggested as a promising drug to prevent or reduce cisplatin-derived ototoxicity. To evaluate the evidence supporting the efficacy of NAC in preventing CIHL, we conducted a systematic review and meta-analysis of the literature.</p><p><strong>Data sources: </strong>A systematic search was conducted on PubMed, Embase, Web of Science, Clinicaltrials.gov, and Cochrane Library.</p><p><strong>Review methods: </strong>Articles reporting the administration of systemic or transtympanic injection of NAC for CIHL prevention were considered. The outcomes of interest included the presence of hearing loss events and changes in hearing thresholds at 0.5 through 12 kHz following cisplatin treatment.</p><p><strong>Results: </strong>A total of 7 studies involving 217 patients met inclusion criteria. Of these patients, 175 received systemic administration of NAC, and the remaining received transtympanic injection of NAC. No significant differences were found in CIHL prevention between the use of either systemic or transtympanic NAC administration compared to placebo (risk ratio [RR] 0.80; 95% confidence interval [CI] 0.54-1.19; P = .28, and RR 0.89; 95% CI 0.51-1.54; P = .67, respectively). No significant differences were found at 0.5 to 8 kHz between groups. Qualitative analyses suggested a tendency to otoprotection in ultra-high frequencies (10 and 12 kHz).</p><p><strong>Conclusion: </strong>Our findings suggest that, regardless of administration route, current published evidence does not show that NAC is effective in preventing CIHL in the standard clinical audiogram range. Further studies with larger samples are needed to confirm our findings.</p><p><strong>Level of evidence: </strong>I.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Secondary Columellar Lengthening in Bilateral Nasal Cleft Deformities With a Sliding Flap Cheilorhinoplasty. 滑瓣鼻翼成形术治疗双侧鼻裂畸形的继发小柱延长。
IF 2.6 3区 医学
Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-05 DOI: 10.1002/ohn.1299
Robert M Frederick, William Dougherty, Eric Dobratz
{"title":"Secondary Columellar Lengthening in Bilateral Nasal Cleft Deformities With a Sliding Flap Cheilorhinoplasty.","authors":"Robert M Frederick, William Dougherty, Eric Dobratz","doi":"10.1002/ohn.1299","DOIUrl":"https://doi.org/10.1002/ohn.1299","url":null,"abstract":"<p><p>A characteristic short columella and decreased nasal projection is common in patients with bilateral cleft lip and palate following primary repair. The main disadvantage of the previously described secondary columellar lengthening procedures is the cosmetically undesirable \"banking\" of forked flaps in the nasal sill. We introduce a modified sliding flap cheilorhinoplasty that involves the recruitment of soft tissue adjacent to lip scars to achieve adequate columellar lengthening without the aforementioned banking of forked flaps. The end result is simultaneous columellar lengthening and lip scar revision.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Importance of Extranodal Extension Grading in Laryngeal Squamous Cell Carcinoma. 结外扩展分级在喉鳞癌中的重要性。
IF 2.6 3区 医学
Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-05 DOI: 10.1002/ohn.1297
Hakan Kara, Levent Aydemir, Melek Büyük, Erol Bozbora, Kübra Özkaya Toraman, Saim Pamuk, Kağan Avcı, Comert Sen, Said Sonmez, Murat Ulusan, Bora Basaran, Musa Altun, Erkan Kıyak
{"title":"The Importance of Extranodal Extension Grading in Laryngeal Squamous Cell Carcinoma.","authors":"Hakan Kara, Levent Aydemir, Melek Büyük, Erol Bozbora, Kübra Özkaya Toraman, Saim Pamuk, Kağan Avcı, Comert Sen, Said Sonmez, Murat Ulusan, Bora Basaran, Musa Altun, Erkan Kıyak","doi":"10.1002/ohn.1297","DOIUrl":"https://doi.org/10.1002/ohn.1297","url":null,"abstract":"<p><strong>Objective: </strong>The primary objective was to investigate the effect of extra-nodal extension (ENE) grading on the survival of pN-positive patients with laryngeal squamous cell carcinoma (LSCC).</p><p><strong>Study design: </strong>A retrospective cohort study.</p><p><strong>Setting: </strong>A tertiary referral center.</p><p><strong>Methods: </strong>The patients with LSCC were retrospectively reviewed. The histopathological slides of patients were re-examined, and ENE was graded. Survival analyses were performed.</p><p><strong>Results: </strong>Seventy-six patients were enrolled in this study. The average age of patients was 61.29 years. 3-year overall survival (OS), disease-specific survival (DSS), and disease-free survival (DFS) rates were 69.7%, 73.7%, and 73.7%, respectively. ENE grading had no statistically significant impact on survival rates.</p><p><strong>Conclusion: </strong>While the presence of ENE in more than 4 lymph nodes, lymph node density (LND) greater than 0.2, poor histologic differentiation, and not receiving chemotherapy were identified as independent poor prognosticators in LSCC, the study did not show any effect of ENE grading on survival rates.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tracking Pleomorphic Adenoma Incidence Trends Over 47 Years: A Population-Based Study. 跟踪多形性腺瘤发病率趋势超过47年:一项基于人群的研究。
IF 2.6 3区 医学
Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-05 DOI: 10.1002/ohn.1292
Katelyn S Rourk, Ghazal S Daher, Jenna R Schwartz, Hawa M Ali, Anne K Shurtz, Kendall K Tasche, Daniel L Price, Kathryn M Van Abel, Linda X Yin, Eric J Moore
{"title":"Tracking Pleomorphic Adenoma Incidence Trends Over 47 Years: A Population-Based Study.","authors":"Katelyn S Rourk, Ghazal S Daher, Jenna R Schwartz, Hawa M Ali, Anne K Shurtz, Kendall K Tasche, Daniel L Price, Kathryn M Van Abel, Linda X Yin, Eric J Moore","doi":"10.1002/ohn.1292","DOIUrl":"https://doi.org/10.1002/ohn.1292","url":null,"abstract":"<p><strong>Objective: </strong>To (1) track the incidence of pleomorphic adenomas (PAs) and (2) compare demographic and treatment trends in PAs over the last five decades in a single county.</p><p><strong>Study design: </strong>Retrospective cohort of all patients with a pathologic diagnosis of nonrecurrent PA from January 1976 to December 2022.</p><p><strong>Setting: </strong>Olmsted County, Minnesota.</p><p><strong>Methods: </strong>Incidence was calculated per 100,000 persons/year and age and sex-adjusted to the US 2020 census data. Incidence trends were identified using Poisson rate regression models. Changes in clinical features of diagnosis were evaluated using Spearman rank correlation coefficient tests, Wilcoxon rank sum tests, and Kruskal-Wallis tests.</p><p><strong>Results: </strong>In total, 251 patients with PA were identified. The median age at diagnosis was 50.0 years with a slight female predominance (1.24:1). The adjusted incidence during this period is 4.79/100,000 person-years, increasing from 2.50 in 1976 to 1979 to 5.73/100,000 persons/year in 2020 to 2022. Less extensive surgery, including partial and superficial parotidectomies, increased significantly from 1976 to 2022, whereas total parotidectomies decreased (P < .0001). The number of patients who presented with an incidental imaging finding increased during this time period (P < .001), as did the age at diagnosis (45-51 years, P = .05) CONCLUSION: The average annual incidence of PAs in Olmsted County from 1976 to 2022 is higher than reported US estimates and has increased over the last five decades. The percentage of patients who presented with incidental imaging findings increased over this period, as did the age at diagnosis. These findings highlight modern imaging techniques and an aging population more willing to seek workup and treatment of a benign parotid mass.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive Value of Digestive Enzymes in Patients With Reflux-Induced Chronic Cough. 消化酶在反流性慢性咳嗽患者中的预测价值。
IF 2.6 3区 医学
Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-02 DOI: 10.1002/ohn.1283
Jerome R Lechien, Nathalie De Vos, Sven Saussez
{"title":"Predictive Value of Digestive Enzymes in Patients With Reflux-Induced Chronic Cough.","authors":"Jerome R Lechien, Nathalie De Vos, Sven Saussez","doi":"10.1002/ohn.1283","DOIUrl":"https://doi.org/10.1002/ohn.1283","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the presence and clinical value of salivary elastase, pepsin, trypsin, cholesterol, and bile salts in the development of laryngopharyngeal reflux disease-related chronic cough (LPRD-CC).</p><p><strong>Study design: </strong>Prospective controlled study.</p><p><strong>Setting: </strong>University hospital study.</p><p><strong>Methods: </strong>Patients with LPRD at the 24-hour hypopharyngeal-esophageal multichannel intraluminal impedance-pH monitoring were recruited from two European hospitals. Symptoms and findings were evaluated with the reflux symptom score (RSS), quality-of-life RSS (QoL-RSS), and the reflux sign assessment (RSA) at baseline and following 3 months of treatment. Pepsin, trypsin, elastase, cholesterol, and bile acids were measured in the saliva of patients. Clinical presentation and enzyme patterns were compared between patients with LPRD-CC versus patients without chronic cough. Predictive values of digestive enzymes on clinical patterns were assessed.</p><p><strong>Results: </strong>Of the 104 recruited patients, 54 had LPRD-CC and 50 did not. Patients with chronic cough demonstrated significantly lower pharyngeal upright reflux events but higher RSS compared to those without chronic cough. The CC group demonstrated significant reduction of RSS (164.4 ± 104.5 vs 105.1 ± 103.2) and RSA (27.7 ± 6.6 vs 21.6 ± 8.1) following treatment. RSS (78.4 ± 51.3 vs 50.2 ± 49.7) and RSA (24.8 ± 7.9 vs 21.5 ± 10.3) were similarly reduced in the non-CC group. The chronic cough group maintained significantly higher scores in otolaryngological RSS (P = .033), respiratory RSS (P = .036), overall RSS (P = .035), and RSS quality of life (RSS-QoL) (P = .007). Salivary elastase demonstrated moderate correlation with both chronic cough presence (r<sub>s</sub> = 0.325) and RSS (r<sub>s</sub> = 0.353), while salivary bile salts correlated strongly with RSS-QoL (r<sub>s</sub> = 0.564). In patients with chronic cough, esophageal acid exposure time showed a significant negative correlation with salivary pH (r<sub>s</sub> = -0.443).</p><p><strong>Conclusion: </strong>LPRD patients with chronic cough demonstrated higher symptom severity than those without, with salivary elastase and bile salts as potential predictors of clinical findings.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between the Dietary Inflammatory Index and Middle Ear Disease in Adults: An NHANES Analysis. 膳食炎症指数与成人中耳疾病之间的关系:一项NHANES分析
IF 2.6 3区 医学
Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-03-07 DOI: 10.1002/ohn.1178
Gaoke Pan, Shenjie Pan, Weiyuan Gong, Jian Zhang
{"title":"Association Between the Dietary Inflammatory Index and Middle Ear Disease in Adults: An NHANES Analysis.","authors":"Gaoke Pan, Shenjie Pan, Weiyuan Gong, Jian Zhang","doi":"10.1002/ohn.1178","DOIUrl":"10.1002/ohn.1178","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the relationship between the dietary inflammatory index (DII) and middle ear disease (MED) in adults using data from the National Health and Nutrition Examination Survey (NHANES) 2015 to 2020.</p><p><strong>Study design: </strong>A cross-sectional analysis was conducted on a sample of American adults to explore the association between DII and MED.</p><p><strong>Setting: </strong>The study utilized data from 3 NHANES cycles (2015-2020), assessing the health and nutritional status of adults and children in the United States.</p><p><strong>Methods: </strong>We analyzed data from 3743 participants aged 20 and older, with MED defined by abnormal tympanogram results. DII was calculated based on dietary intake data recorded during the 24 hours before the interview. Logistic regression models were used to examine the association between DII and MED, adjusted for various demographic and health-related factors.</p><p><strong>Results: </strong>The results revealed a significant positive association between higher DII scores and the likelihood of MED, particularly in individuals under 60 years of age. A nonlinear relationship was identified, with a threshold effect at a DII value of 2.74, below which higher DII was associated with increased risk of MED, while the association weakened above this threshold.</p><p><strong>Conclusion: </strong>This study suggests that inflammatory dietary patterns are associated with an increased risk of MED, especially in younger adults. The findings underscore the importance of dietary interventions in preventing and managing MED and warrant further prospective studies to confirm these results and understand the mechanisms by which diet affects middle ear health.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"1649-1655"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preservation Palatopharyngoplasty for Obstructive Sleep Apnea With High Modified Mallampati Scores: Clinical and Polysomnographic Outcomes. 保留腭咽成形术治疗具有高改良Mallampati评分的阻塞性睡眠呼吸暂停:临床和多导睡眠图结果。
IF 2.6 3区 医学
Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-01 Epub Date: 2025-03-07 DOI: 10.1002/ohn.1184
Mohamed Abdelwahab, Mohamed Faisal Kassir, Nicolas S Poupore, Robson Capasso, Shaun A Nguyen
{"title":"Preservation Palatopharyngoplasty for Obstructive Sleep Apnea With High Modified Mallampati Scores: Clinical and Polysomnographic Outcomes.","authors":"Mohamed Abdelwahab, Mohamed Faisal Kassir, Nicolas S Poupore, Robson Capasso, Shaun A Nguyen","doi":"10.1002/ohn.1184","DOIUrl":"10.1002/ohn.1184","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to describe and evaluate clinical and polysomnographic outcomes of the preservation palatopharyngoplasty procedure, which preserves pharyngeal mucosa and muscles, in patients with obstructive sleep apnea with high modified Mallampati scores (3 or 4).</p><p><strong>Study design: </strong>A retrospective chart review.</p><p><strong>Setting: </strong>A tertiary medical center.</p><p><strong>Methods: </strong>A total of 23 patients who underwent preservation palatopharyngoplasty between November 2022 and May 2024 were included. Outcomes measured were apnea-hypopnea index (AHI), oxygen desaturation index (ODI), Epworth Sleepiness Scale (ESS) scores, and Nasal Obstruction Symptom Evaluation (NOSE) Scale scores pre- and postsurgery. Data were analyzed using unpaired or paired t-tests, and statistical significance was set at P < .05.</p><p><strong>Results: </strong>The mean age of included patients was 51.74 years. Postoperative results showed a significant 25.48% (standard deviation [SD] = 32.59) decrease in AHI (P = .0011) and 35.25% (SD = 11.00) mean decrease in ODI (P = .0030). REM sleep percentage increased from 12.96% to 21.35% (P = .0106), and REM AHI decreased from 55.49 to 40.02 events/h (P = .0255). Significant improvements were also seen in ESS (P = .0123) and NOSE scores (P = .0134). Among the included patients, 12 out of 23 patients achieved surgical success per Sher's criteria.</p><p><strong>Conclusion: </strong>The preservation palatopharyngoplasty significantly improved subjective and objective measures in OSA patients with higher Mallampati scores by enhancing upper airway patency and reducing OSA severity.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"1789-1796"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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