Shaunak N Amin, Megan Branson, J Nathaniel Perkins, Xing Wang, Eric C Huang, Tyler G Ketterl, Hedieh Khalatbari, Sanjay R Parikh, Scott C Manning, John P Dahl
{"title":"TI-RADS and Bethesda Classification System Correlate With Predicting Pediatric Papillary Thyroid Carcinoma.","authors":"Shaunak N Amin, Megan Branson, J Nathaniel Perkins, Xing Wang, Eric C Huang, Tyler G Ketterl, Hedieh Khalatbari, Sanjay R Parikh, Scott C Manning, John P Dahl","doi":"10.1002/ohn.1310","DOIUrl":"https://doi.org/10.1002/ohn.1310","url":null,"abstract":"<p><strong>Objective: </strong>Our study objectives were to evaluate the relationship between Thyroid Imaging Reporting and Data System (TI-RADS) and Bethesda classification and to compare both TI-RADS and Bethesda classification for the diagnosis of papillary thyroid carcinoma (PTC) within the pediatric population.</p><p><strong>Study design: </strong>Retrospective case series.</p><p><strong>Setting: </strong>Academic pediatric hospital.</p><p><strong>Methods: </strong>A 13-year retrospective review was performed of all pediatric patients undergoing thyroid fine needle aspiration (FNA) and ultrasound at our institution. Demographics, TI-RADS scoring, FNA results, surgical history, and final pathology were collected. High-risk ultrasonography and cytopathology were defined as TI-RADS 3-5 and Bethesda 5-6, respectively. Spearman's rank correlation was determined for TI-RADS and Bethesda classification. Relative risks of high-risk TI-RADS and Bethesda classification for predicting PTC were calculated.</p><p><strong>Results: </strong>A total of 157 patients (21.7% male, median age at time of FNA 15 years, and range 2.7-21 years) underwent ultrasound and FNA during the study. The Spearman's rank correlation coefficient for TI-RADS compared with the Bethesda classification was 0.41 (P < .001). The relative risk of high-risk TI-RADS scores to predict the presence of PTC was 7.99 (95% CI 1.16-54.90). High-risk Bethesda classification demonstrated a relative risk for predicting PTC of 6.62 (95% CI 4.22-10.41).</p><p><strong>Conclusion: </strong>In our cohort, there was a moderate correlation between TI-RADS and Bethesda classifications. Patients with a TI-RADS score ≥3 and Bethesda classification 3 or 4 are at intermediate risk for harboring PTC and should be counseled accordingly.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nathaniel S Neptune, Jeanne L Hatcher, Jeremy S Collins, Andrew Tkaczuk, Anupriya Rao, Jay A Sanford
{"title":"Safe Use of High-Flow Oxygenation During Transoral Laser Microsurgery Without Airway Fire: A Review of 369 Consecutive Cases.","authors":"Nathaniel S Neptune, Jeanne L Hatcher, Jeremy S Collins, Andrew Tkaczuk, Anupriya Rao, Jay A Sanford","doi":"10.1002/ohn.1293","DOIUrl":"https://doi.org/10.1002/ohn.1293","url":null,"abstract":"<p><strong>Objective: </strong>Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) is often avoided during intraoral laser use due to the concern for an airway fire with the addition of high-flow oxygen. We aim to demonstrate that THRIVE can be safely used during transoral laser microsurgery (TLM) without causing an airway fire or other major complications.</p><p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Emory University Hospital Midtown between January 2020 and April 2024.</p><p><strong>Methods: </strong>A retrospective chart review of all patients who underwent TLM with the use of THRIVE was performed. A standardized laser safety protocol was followed, and either a carbon dioxide or potassium titanyl phosphate laser was used for all cases.</p><p><strong>Results: </strong>In total, 369 cases were examined, and no fire, ignition, flash, or major complication occurred. In total, 270 (73.2%) patients were Caucasian females and 271 (73.4%) patients had a primary diagnosis of idiopathic subglottic stenosis. A total of 110 (29.8%) cases were completed with the use of THRIVE alone, 238 (64.5%) required the addition of jet ventilation, and 21 (5.7%) required intubation for the completion of the case. Increased body mass index was positively associated with the need for jet ventilation or intubation and reached statistical significance for the type of airway management employed during the case (P-value < .001).</p><p><strong>Conclusion: </strong>Airway fire and other major complications are preventable with the use of THRIVE during TLM if standardized laser safety practices are implemented.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evan J Patel, Xin Wu, Joel McLouth, Daniel Q Sun, Bryan K Ward, Jeffrey D Sharon
{"title":"Pain, Safety, and Image Quality of Magnetic Resonance Imaging With Cochlear Implants: A Prospective Trial.","authors":"Evan J Patel, Xin Wu, Joel McLouth, Daniel Q Sun, Bryan K Ward, Jeffrey D Sharon","doi":"10.1002/ohn.1301","DOIUrl":"https://doi.org/10.1002/ohn.1301","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate whether rotating cochlear implant (CI) magnets improve patient comfort and preserve scan usability during magnetic resonance imaging (MRI).</p><p><strong>Study design: </strong>Prospective cohort study.</p><p><strong>Setting: </strong>Two tertiary academic centers.</p><p><strong>Methods: </strong>Adult patients with CIs who underwent MRI of any body region were included. The primary outcome was the mean change in pain score from baseline (before any study procedure) to the highest reported pain level during MRI with a CI magnet in place. Secondary outcomes included patient-reported survey responses regarding their MRI experience and the interpretability of the brain MRI scans involving rotating magnets, as assessed by two independent, blinded neuroradiologists.</p><p><strong>Results: </strong>Twenty-three MRI scans (21 patients) with CIs were analyzed. Eleven scans (47.8%) involved implants containing internal magnets designed to self-align with the magnetic field. The mean pain-score difference unrelated to headwrap use was significantly lower for rotating magnet devices than fixed magnets (0.7 vs 4.0, P = .02). No magnet displacement or depolarization occurred. In six MRI brain sequences, the mean maximal signal-loss artifact measured 6.1 cm (SD 1.2 cm) on axial images for rotating magnet devices. When assessing if the MRI could answer the question for which the scan was ordered, 100% of responses (n = 12) ranged from slightly agree to strongly agree. The majority of patients (70.0%) indicated they would undergo another MRI if medically necessary.</p><p><strong>Conclusion: </strong>CIs containing rotatable magnets reduce MRI-related pain compared to those with fixed magnets. Although the magnets produce a measurable artifact, it does not substantially compromise scan utility in the majority of cases.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Platelet-Rich Plasma for Rhinitis Medicamentosa: A Promising Histopathological Study in an Animal Model.","authors":"Kamil Gokce Tulaci, Salih Yayman, Erhan Arslan, Hasan Canakci, Tugba Tulaci, Gülay Turan, Omer Hizli, Hasmet Yazici","doi":"10.1002/ohn.1303","DOIUrl":"https://doi.org/10.1002/ohn.1303","url":null,"abstract":"<p><strong>Objective: </strong>To investigate whether platelet-rich plasma (PRP) has an efficacy on histopathologic changes in rhinitis medicamentosa (RM) in a rat model.</p><p><strong>Study design: </strong>Experimental animal study.</p><p><strong>Setting: </strong>University animal laboratory.</p><p><strong>Methods: </strong>Forty Wistar albino rats were randomly assigned to five groups to assess the effects of various treatments on RM. Group 1 received intranasal normal saline solution (NSS) for 60 days and served as the negative control. Group 2 was administered intranasal oxymetazoline for 60 consecutive days to induce RM. After decapitation, histopathological evaluation confirmed the development of RM in group 2. The remaining three groups were then similarly treated with oxymetazoline for 60 days. Following this period, group-specific treatments were applied for an additional 15 days: group 3 received NSS, group 4 was treated with intranasal corticosteroids, and group 5 received intranasal PRP. Nasal mucosal samples were harvested and subjected to histopathological evaluation to determine treatment-related changes.</p><p><strong>Results: </strong>Intranasal PRP treatment significantly reduced submucosal edema and improved submucosal gland degeneration (SGD) scores in the nasal mucosa. Moreover, PRP treatment led to a greater reduction in total histopathological score compared to steroid treatment (P = .007).</p><p><strong>Conclusion: </strong>This study demonstrated that PRP administration effectively ameliorates submucosal edema, SGD, and total histopathologic score in experimentally induced RM. Given that PRP is an autologous product with a low risk of side effects, it may serve as a promising alternative to steroids in the treatment of RM.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadia L Samaha, Maria Armache, Wassim Najjar, Rachel Stemme, Wendy Chen, Leila J Mady, Tiffany P Hwa
{"title":"Exploring Gender Differences: Training, Practice, and Family Dynamics Among Fellowship-Trained Neurotologists.","authors":"Nadia L Samaha, Maria Armache, Wassim Najjar, Rachel Stemme, Wendy Chen, Leila J Mady, Tiffany P Hwa","doi":"10.1002/ohn.1296","DOIUrl":"https://doi.org/10.1002/ohn.1296","url":null,"abstract":"<p><strong>Objective: </strong>To characterize and examine gender differences in training paths, practice patterns, family dynamics, and career trajectories in the field of neurotology.</p><p><strong>Study design: </strong>Cross-sectional survey.</p><p><strong>Setting: </strong>Research Electronic Data Capture (RedCap) Framework.</p><p><strong>Methods: </strong>A survey was created and distributed electronically to fellowship-trained neurotologists in the United States who were identified via publicly available information. Descriptive, univariate, and multivariate statistics were performed.</p><p><strong>Results: </strong>Of the 223 neurotologists invited, 80 (35.8%) responded. Most participants were male (77.5%, n = 62), white (77.5%, n = 62), and aged 41 years or older (81.2%, n = 65). Training and practice patterns showed no significant gender differences. However, women were more likely to have a physician spouse (55.6% vs 25.8%, P = .02), have their first child post-fellowship (55.6% vs 24.2%, P = .007), rely on professional childcare (47.1% vs 22.6%, P = .05), and reduce work hours due to childcare needs (22.2% vs 6.45%, P = .05). Men were more likely to rely on their spouse as the primary caretaker (48.4% vs 5.9%, P = .001). Having a physician spouse was associated with post-fellowship childbearing (48.1% vs 28.9%, P = .041) and increased use of professional childcare (44.3% vs 30.1%, P = .05), regardless of gender.</p><p><strong>Conclusion: </strong>Although training and practice patterns were similar across genders, significant differences in family structure, childbearing, and caretaking roles suggest that women in neurotology may face unique challenges that could influence their career progression.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tyler A Durham, Basir S Mansoor, Stephen R Chorney, Ron B Mitchell, Alex Najjar, Romaine F Johnson
{"title":"Association Between Severe Obesity and Pediatric Obstructive Apnea-A Retrospective Case Series.","authors":"Tyler A Durham, Basir S Mansoor, Stephen R Chorney, Ron B Mitchell, Alex Najjar, Romaine F Johnson","doi":"10.1002/ohn.1295","DOIUrl":"https://doi.org/10.1002/ohn.1295","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the impact of severe obesity on the severity of pediatric obstructive sleep apnea (OSA).</p><p><strong>Study design: </strong>Retrospective case series.</p><p><strong>Setting: </strong>Tertiary stand-alone pediatric hospital.</p><p><strong>Methods: </strong>Consecutive children with obesity (≥95th percentile body mass index [BMI]) who underwent full-night polysomnography between January 2021 and December 2021 were analyzed. Patients were categorized into obesity (≥95th percentile BMI and <120% of the 95th percentile) and severe obesity (≥120% of the 95th percentile BMI). The association between severe obesity and severe OSA was assessed using multiple logistic regression.</p><p><strong>Results: </strong>The study included 282 patients with a median age of 9.2 years (interquartile range 5.9-12.3), 63% male, and 65% Hispanic. In total, 53% were severely obese. Severely obese children had a higher prevalence of severe OSA (53% vs 33%, P < .001) and very severe OSA (apnea-hypopnea index ≥ 24; 24% vs 11%, P = .006). Multiple logistic regression revealed that severe obesity was associated with severe OSA (adjusted odds ratio [aOR] = 3.44; 95% confidence interval [CI], 1.82-6.53; P < .001) after adjusting for age, sex, and tonsillar hypertrophy. Among 170 patients who underwent posttonsillectomy polysomnography, 29% exhibited residual OSA, with 19% having residual severe OSA. Class 3 severe obesity was associated with residual OSA (aOR = 4.05, 95% CI = 1.09-15.00).</p><p><strong>Conclusion: </strong>Children with severe obesity face substantial sleep disturbances and a heightened risk of residual OSA following adenotonsillectomy.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annie R Thornton, Emily A Montgomery, M Elise Graham, Charles A Riley, Claire M Lawlor
{"title":"Systematic Review of Tongue Tie Publications: Exponential Rise in Publications Without Exponential Increase in Evidence.","authors":"Annie R Thornton, Emily A Montgomery, M Elise Graham, Charles A Riley, Claire M Lawlor","doi":"10.1002/ohn.1264","DOIUrl":"https://doi.org/10.1002/ohn.1264","url":null,"abstract":"<p><strong>Objective: </strong>Ankyloglossia and lingual frenotomy in young children and infants remains an area of debate, with a body of research with poor quality-but increasing number-of studies, a trend that has continued into the present day. To systematically review the published literature to identify the number, type, and quality of studies on the evaluation, diagnosis, and treatment of ankyloglossia.</p><p><strong>Data sources: </strong>In this Preferred Reporting Items for Systematic Reviews and Meta-Analyses systematic review, a literature search of PubMed, Embase, and Ovid MEDLINE was conducted in 2024 using keywords related to ankyloglossia and frenotomy.</p><p><strong>Review methods: </strong>Studies from 2017 to 2024 were assessed by two independent reviewers. Articles were included if they focused on ankyloglossia in children and in the English language.</p><p><strong>Results: </strong>Overall, 462 articles were included for full-text extraction, of which cohort studies were the most common (179, 38.7%), and randomized controlled trials (RCTs; 13, 2.8%) were among the least common. Studies on different frenotomy techniques were common, despite no evidence suggesting that no intervention may be superior. There was an overall lack of study endpoints with objective measures such as breastfeeding duration or infant growth rates postprocedure. Despite the presence of several classification systems for ankyloglossia, none of those described in the literature focuses primarily on function as opposed to appearance or other factors.</p><p><strong>Conclusion: </strong>This systematic review provides an update demonstrating the continued exponential rise of publications focused on ankyloglossia and lingual frenotomy without a rise in evidence clarifying the controversies surrounding these important topics. Future studies in this area should be quality RCTs with meaningful outcome measures.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiofrequency Ablation as a Palliative Treatment for Advanced Primary Papillary Thyroid Carcinoma Ineligible for Surgery.","authors":"Dongbin Ahn, Ji Hye Kwak, Sung Jae Heo","doi":"10.1002/ohn.1307","DOIUrl":"https://doi.org/10.1002/ohn.1307","url":null,"abstract":"","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Macario Camacho, Yoseph A Kram, Forrest D Craig, Sungjin A Song, Edward T Chang, Victor Certal, Jason L Acevedo, Scott E Brietzke, Nolan N Jones
{"title":"Randomized Trials Comparing Inferior Turbinoplasty Techniques for Nasal Obstruction: A Meta-analysis.","authors":"Macario Camacho, Yoseph A Kram, Forrest D Craig, Sungjin A Song, Edward T Chang, Victor Certal, Jason L Acevedo, Scott E Brietzke, Nolan N Jones","doi":"10.1002/ohn.1269","DOIUrl":"https://doi.org/10.1002/ohn.1269","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to systematically review the international literature for randomized trials presenting subjective, long-term outcomes (1-3 years) for nasal obstruction treated with inferior turbinoplasties, followed by a meta-analysis.</p><p><strong>Data sources: </strong>PubMed/MEDLINE and 5 other databases.</p><p><strong>Review methods: </strong>Two authors searched through October 27, 2024.</p><p><strong>Results: </strong>Four randomized trials with 2874 patients provided outcomes after bilateral inferior turbinoplasties. At 2 years, the microdebrider visual analog scale (VAS) values reduced 81.7% from 8.2 ± 1.4 to 1.5 ± 0.7, the submucosal resection reduced 82.4% from 8.5 ± 1.0 to 1.5 ± 0.6, outfracturing reduced 82.8% from 8.7 ± 1.1 to 1.5 ± 0.7, and radiofrequency ablation increased 8.1% from 7.4 ± 1.0 to 8.0 ± 1.4. At 3 years, the microdebrider VAS values reduced 80.5% from 8.2 ± 1.4 to 1.6 ± 0.8, the submucosal resection reduced 82.4% from 8.5 ± 1.0 to 1.5 ± 0.7, outfracturing reduced 82.8% from 8.7 ± 1.1 to 1.5 ± 0.8, and radiofrequency ablation increased 12.2% from 7.4 ± 1.0 to 8.3 ± 1.4.</p><p><strong>Conclusion: </strong>In this systematic review, evaluating data at 2 and 3 years after inferior turbinoplasties, the procedures that removed tissue or outfractured had approximately 80% improvement in the VAS, while techniques that did not remove tissue or outfracture tended to have a recurrence of their nasal obstruction. Additional research is needed.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maaike Jellema, Esther E Blijleven, Joeri Buwalda, Raphael J B Hemler, Huib F van Waegeningh, Robert J Stokroos, Inge Wegner, Henricus G X M Thomeer
{"title":"Patient's Perspective and Change in Quality of Life After Stapes Surgery: A Multicenter Prospective Trial.","authors":"Maaike Jellema, Esther E Blijleven, Joeri Buwalda, Raphael J B Hemler, Huib F van Waegeningh, Robert J Stokroos, Inge Wegner, Henricus G X M Thomeer","doi":"10.1002/ohn.1298","DOIUrl":"https://doi.org/10.1002/ohn.1298","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated outcomes of stapes surgery in otosclerosis patients by assessing audiometric results and health-related quality of life (HRQOL) using the Dutch Stapesplasty Outcome Test-25 (SPOT-25) questionnaire. Additionally, the role of SPOT-25 in preoperative decision-making and as a follow-up tool was explored.</p><p><strong>Study design: </strong>A prospective, multicenter cohort study.</p><p><strong>Setting: </strong>One tertiary academic medical center and 3 secondary referral centers.</p><p><strong>Methods: </strong>Data from 115 adult patients undergoing primary stapes surgery was analyzed. Audiometric outcomes were measured using pure-tone audiometry results and word recognition score (WRS). HRQOL was assessed using SPOT-25, Glasgow Health Status Questionnaire, and Glasgow Benefit Inventory. Pre- and postoperative outcomes were compared, and correlations between pure-tone audiometry results, WRS, and HRQOL were analyzed. Outcomes were compared between patients receiving 0.4 and 0.6 mm diameter pistons, and the impact of preoperative pure-tone audiometry results was analyzed.</p><p><strong>Results: </strong>Significant postoperative improvements were observed in all audiometric measures (mean air conduction gain of 22 dB and air-bone gap (ABG) improvement of 18 dB). HRQOL also improved significantly (mean SPOT-25 score improved from 48 to 27). The 0.6 mm piston group had a significantly smaller postoperative ABG than the 0.4 mm group. Patients with a preoperative ABG ≤ 15 dB had a mean SPOT-25 gain of 19 (SD 22), whereas those with a preoperative ABG > 15 dB had a gain of 21 (SD 18).</p><p><strong>Conclusion: </strong>Stapes surgery significantly improves hearing and HRQOL. The SPOT-25 is a valuable tool for evaluating HRQOL and may assist in preoperative decision-making in patients with varying hearing impairments.</p><p><strong>Level of evidence: </strong>III.</p>","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}