Otolaryngology- Head and Neck Surgery最新文献

Characteristics and Prognosis of Patients With Non-Syndromic Sensorineural Hearing Loss Associated With Myo15a Mutations. 与Myo15a突变相关的非综合征性感音神经性听力损失患者的特征和预后

IF 2.6 3区医学

Otolaryngology- Head and Neck Surgery Pub Date : 2025-06-01 Epub Date: 2025-03-07 DOI: 10.1002/ohn.1200

Yueying Wang, Shubin Fang, Xiaoqing Cen, Yue Liang, Anhai Chen, Lusha Huang, Juan Wang, Guanxia Xiong, Kaitian Chen

{"title":"Characteristics and Prognosis of Patients With Non-Syndromic Sensorineural Hearing Loss Associated With Myo15a Mutations.","authors":"Yueying Wang, Shubin Fang, Xiaoqing Cen, Yue Liang, Anhai Chen, Lusha Huang, Juan Wang, Guanxia Xiong, Kaitian Chen","doi":"10.1002/ohn.1200","DOIUrl":"10.1002/ohn.1200","url":null,"abstract":"Objective: This study aims to investigate the characteristics of hearing loss associated with MYO15A mutations and to analyze the longitudinal prognosis over a 4-year period using different treatment modalities, including cochlear implants (CIs), hearing aids (HAs), and conservative management.Study design: A retrospective case review.Setting: A tertiary referral center.Methods: Sequencing was performed to recruit patients with potentially pathogenic MYO15A mutation-induced hearing loss. Audiological data, radiological imaging, and assessment of hearing and speech performance before and after different treatments were analyzed in combination with patients' genotypes.Results: Sixteen patients with MYO15A mutation-induced deafness from 14 unrelated pedigrees were enrolled, carrying 5 previously unreported mutations: c.3660_3666delinsAA (p.Glu1221fs), c.4635delG (p.Val1545fs), c.6664A>G (p.Met2222Val), c.8215delG (p.Ala2739fs), and c.8897delG (p.Gly2966fs). Inner ear malformations were observed in 3 patients. CI recipients exhibited significant improvements in hearing and speech abilities 1-year post-implantation, while individuals using HAs showed a gradual improvement trend over a 4-year period. Notably, even those with bilateral cochlear aperture atresia achieved satisfactory hearing and speech outcomes following early CIs.Conclusion: Patients with MYO15A mutations who underwent CIs generally demonstrated earlier improvements in hearing and speech development compared to those using HAs. Early genetic detection and timely implementation of assistive acoustic stimulation are recommended for optimal outcomes.","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"2051-2057"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictors of Hypoglossal Nerve Stimulator Usage: A Growth Curve Analysis Study. 舌下神经刺激器使用的预测因素：生长曲线分析研究。

IF 2.6 3区医学

Otolaryngology- Head and Neck Surgery Pub Date : 2025-06-01 Epub Date: 2025-03-11 DOI: 10.1002/ohn.1219

Cynthia M Chweya, Rahul Alapati, Adip G Bhargav, Robert Wright, Antonio Bon Nieves, Kiara Holtkamp, David Rouse, Christopher Larsen

{"title":"Predictors of Hypoglossal Nerve Stimulator Usage: A Growth Curve Analysis Study.","authors":"Cynthia M Chweya, Rahul Alapati, Adip G Bhargav, Robert Wright, Antonio Bon Nieves, Kiara Holtkamp, David Rouse, Christopher Larsen","doi":"10.1002/ohn.1219","DOIUrl":"10.1002/ohn.1219","url":null,"abstract":"Objective: The purpose of this study is to evaluate the long-term usage of the hypoglossal nerve stimulator and identify predictors of usage over time.Study design: Retrospective chart review.Setting: Tertiary academic medical center and database.Methods: Single institution retrospective chart review was merged with Inspire SleepSync device usage data. Growth curve modeling was performed with a linear mixed-effects model to evaluate usage hours over time. A logistic regression analysis was also performed to assess the relationship between early adherence and adherence at 1 and 2 years.Results: A total of 352 patients were included in the study. Seventy percent were male and the mean age was 64 ± 12 years. Adherence at 6 months was significantly predictive of adherence at 12 (odds ratio [OR] 9.42, CI 3.23-28.76, P < .001) and 24 (OR 3.03, CI 0.96-9.05, P = .049) months. Older age (estimate = 0.019, SE 0.006, P = .002) and greater days of use per biweekly period (estimate = 0.142, SE 0.004, P < .001) were positive predictors of usage. Insomnia (estimate = -0.386, SE 0.128, P = .003) and higher device mean voltage amplitude (estimate = -0.348, SE 0.020, P < .001) were negative predictors.Conclusion: Time since activation does not appear to have an impact on hypoglossal nerve stimulator therapy usage. Insomnia and higher device voltage were associated with a statistically significant negative trend in therapy usage, whereas older age and greater number of days used may be predictive of higher therapy usage. Identifying predictors of usage will enable identification of at-risk patients and allow for early implementation of targeted interventions to improve patient adherence and optimize long-term health outcomes.","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"2116-2123"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes Following Single-Stage Laryngotracheal Reconstruction Using a "No Look" Extubation Philosophy. 采用“不看”拔管理念的单期喉气管重建的结果。

IF 2.6 3区医学

Otolaryngology- Head and Neck Surgery Pub Date : 2025-06-01 Epub Date: 2025-03-19 DOI: 10.1002/ohn.1159

Andrew R Scott, David O Danis, Andrea B Clinch, Lindsey Greenlund, Brianne B Roby

{"title":"Outcomes Following Single-Stage Laryngotracheal Reconstruction Using a \"No Look\" Extubation Philosophy.","authors":"Andrew R Scott, David O Danis, Andrea B Clinch, Lindsey Greenlund, Brianne B Roby","doi":"10.1002/ohn.1159","DOIUrl":"10.1002/ohn.1159","url":null,"abstract":"Objective: This study aims to examine outcomes following single-stage laryngotracheal reconstruction (SSLTR) using a \"no look\" philosophy.Study design: Case series with chart review.Setting: Two urban, tertiary, children's hospitals.Methods: Patients underwent primary or revision open SSLTR by 1 of 3 surgeons at 2 institutions. After a period of planned postoperative intubation, patients were extubated in the pediatric intensive care unit (PICU), with operative inspection of the airway deferred for 6 weeks unless symptoms of stridor or distress developed postoperatively. Short-term and long-term clinical outcome metrics were examined.Results: From 2011 to 2021, 47 consecutive SSLTRs were completed, following which patients were extubated in the PICU without antecedent inspection of the airway. The mean age was 30.8 months (range: 3-130 months), and the mean preoperative stenosis grade was 2.1. There were 17 anterior grafts, 1 isolated posterior graft, and 29 A/P graft procedures; 19% of surgeries were revisions of prior open procedures. The mean PICU and hospital length of stay were 10.1 and 12.5 days, respectively. The failure rate following extubation was 4% (0% primary and 22% revision, P < .003), and 23% of patients had an unplanned return to the operating room for airway symptoms (21% primary and 33% revision, P = .44). Secondary endoscopic interventions were performed in 47% of cases; when required, the mean number of dilations was 2.2 (1.6 primary and 3.7 revision, P < .05). Long-term outcomes compared favorably with historical standards.Conclusion: In select patients undergoing SSLTR, a \"no look\" philosophy may eliminate unnecessary surgical procedures without compromising short-term or long-term clinical outcomes.","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"1995-2002"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscopic Pituitary Surgery in High-Resource Settings Versus a Public Hospital in Ghana. 高资源环境与加纳公立医院的内窥镜垂体手术

IF 2.6 3区医学

Otolaryngology- Head and Neck Surgery Pub Date : 2025-06-01 Epub Date: 2025-04-10 DOI: 10.1002/ohn.1263

Katherine Y Tai, Daniel B Spielman, Lauren H Tucker, Kafui Searyoh, Loius Armooh, Confidence K Nai, Amanda Quarshie, Divine A Kwami, Jerome K Boatey, Patrick Bankah, George K Wepeba, Rodney J Schlosser, Michael G Stewart, Jonathan B Overdevest, David A Gudis

{"title":"Endoscopic Pituitary Surgery in High-Resource Settings Versus a Public Hospital in Ghana.","authors":"Katherine Y Tai, Daniel B Spielman, Lauren H Tucker, Kafui Searyoh, Loius Armooh, Confidence K Nai, Amanda Quarshie, Divine A Kwami, Jerome K Boatey, Patrick Bankah, George K Wepeba, Rodney J Schlosser, Michael G Stewart, Jonathan B Overdevest, David A Gudis","doi":"10.1002/ohn.1263","DOIUrl":"10.1002/ohn.1263","url":null,"abstract":"Objective: The evidence supporting endoscopic transsphenoidal pituitary adenoma resection (TSPR) is predominantly from skull base centers in high-resource settings (HRSs). This study is the first comparative analysis of TSPR performed at a low-resource setting (LRS), Korle Bu Teaching Hospital (KBTH), a public hospital in Accra, Ghana, versus HRS.Study design: Cohort study.Setting: Tertiary skull base surgery centers in Ghana, the United States, Canada, and Australia.Methods: Patients who underwent TSPR at KBTH from 2021 to 2023 were compared to a multi-institutional cohort of TSPR patients from skull base centers in the United States, Canada, and Australia. Univariate and multivariate analyses were performed controlling for available demographic characteristics and medical history.Results: The KBTH cohort included 93 patients, and the HRS cohort included 1112 patients of similar age. The HRS cohort had higher incidences of diabetes (P = .013) and cancer history (P = .012). There were two deaths in the KBTH cohort (one intracranial bleed, one meningitis) versus five in the HRS cohort (odds ratio [OR] = 8.07, 95% CI 1.28, 50.98). There were no differences in rates of other postoperative complications.Conclusion: These findings demonstrate the capacity of LRSs to perform endoscopic pituitary surgery and highlight the need for building rhinologic and skull base surgery capacity around the world. This study was unable to control for important factors including tumor size, postoperative access to health care resources, availability of adjuvant treatments such as neuro-interventional radiology and stereotactic radiation therapy, and others.","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"2111-2115"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Online Discourse and Trends Surrounding HPV Vaccination for Head and Neck Cancer Prevention. 围绕HPV疫苗预防头颈癌的在线讨论和趋势。

IF 2.6 3区医学

Otolaryngology- Head and Neck Surgery Pub Date : 2025-06-01 Epub Date: 2025-03-19 DOI: 10.1002/ohn.1222

Andrew Meci, Christopher C Tseng, Zackary Jensen, Neerav Goyal

{"title":"Online Discourse and Trends Surrounding HPV Vaccination for Head and Neck Cancer Prevention.","authors":"Andrew Meci, Christopher C Tseng, Zackary Jensen, Neerav Goyal","doi":"10.1002/ohn.1222","DOIUrl":"10.1002/ohn.1222","url":null,"abstract":"Objective: In 2020, the Food and Drug Administration (FDA) approved Merck's GARDASIL 9 for prevention of certain human papillomavirus (HPV)-related head and neck cancer. This study characterizes the sentiment and themes of HPV vaccination online discourse surrounding the 2020 FDA recommendation.Study design: Retrospective cohort.Setting: Data from 2018 to 2022: Reddit, Teen VaxView (Centers for Disease Control and Prevention), and Google Trends.Methods: Online public discourse was assessed by searching Reddit for user submitted posts using relevant keywords. Reddit posts were categorized by a trained machine learning classifier. Natural language processing calculated positive/negative sentiment, polarity, and frequent nonstop words. Google Trends assessed relative search popularity, and TeenVaxView assessed HPV vaccinations among adolescents. Statistical relationships were assessed using linear and logarithmic regression models.Results: Analysis of 2751 Reddit posts demonstrated a balanced overall positive/negative sentiment, with a substantial positive trend over the study period (P = .05). Most posts were personal stories/questions (n = 1997, 72.6%) and conspiracy posts made up a just a small minority (n = 186, 6.8%). Discussion including head and neck anatomical and cancer terms significantly increased (P = .01). Vaccination coverage trended upward significantly for males and females (P < .01). A significant relationship was found between positive sentiment trend and vaccination coverage (P = .02).Conclusion: Discourse surrounding the HPV vaccine has been increasingly positive in sentiment and changes in FDA guidelines correlated with increased discussion of HPV-related head and neck cancer. There was a concurrent increased adolescent vaccination rate.","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"1962-1970"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physical Features Contributing to Gender Dysphoria: The Role of Voice. 身体特征对性别焦虑的影响：声音的作用。

IF 2.6 3区医学

Otolaryngology- Head and Neck Surgery Pub Date : 2025-06-01 Epub Date: 2025-03-19 DOI: 10.1002/ohn.1207

Serena Pu, Leanne Goldberg, Jennifer Ren, A C Goldberg, Mark Courey

{"title":"Physical Features Contributing to Gender Dysphoria: The Role of Voice.","authors":"Serena Pu, Leanne Goldberg, Jennifer Ren, A C Goldberg, Mark Courey","doi":"10.1002/ohn.1207","DOIUrl":"10.1002/ohn.1207","url":null,"abstract":"Objective: Features that cause gender incongruence (gender identity not aligning with assumptions based on sex assigned at birth) in transgender individuals often motivate them to seek out gender-affirming treatments. Voice has rarely been included as a major contributor to gender dysphoria. The primary objective of this study is to understand the significance of dysphoria related to voice compared to dysphoria secondary to other features.Study design: Prospective population-based survey study.Setting: Social media.Methods: The survey requested a ranking of features that contribute to gender dysphoria, whether the features were bothersome due to external or internal perception, and self-reported ideal order for pursuing gender-affirming treatments. The categories of features that were ranked included upper body, lower body, face, neck, voice, and height.Results: In total, 79% of respondents experience gender incongruence secondary to their voice. Voice was the second most important feature contributing to gender dysphoria, only after upper body. In transgender men (29.4%) and transgender women (25%), voice was both the second most important feature contributing to gender dysphoria and the second most important intervention to alleviate gender dysphoria. Specifically, vocal incongruence is largely due to perception by others, as opposed to lower body which contributes to incongruence due to perception by self.Conclusion: Voice is the second most common contributor to gender dysphoria after upper body. Due to self-rated importance of voice to gender incongruence, health care providers must be aware that voice interventions are critical to improve gender dysphoria experienced by transgender individuals.","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"2018-2025"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12120044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Localized Knockout of E-Cadherin in Subglottic Mucosa Increases Fibrosis. 声门下粘膜E-Cadherin的局部敲除增加纤维化。

IF 2.6 3区医学

Otolaryngology- Head and Neck Surgery Pub Date : 2025-06-01 Epub Date: 2025-03-19 DOI: 10.1002/ohn.1226

Raymond J So, Samuel L Collins, Yee Chan-Li, Ioan Lina, Alexander Gelbard, Kevin M Motz, Alexander T Hillel

{"title":"Localized Knockout of E-Cadherin in Subglottic Mucosa Increases Fibrosis.","authors":"Raymond J So, Samuel L Collins, Yee Chan-Li, Ioan Lina, Alexander Gelbard, Kevin M Motz, Alexander T Hillel","doi":"10.1002/ohn.1226","DOIUrl":"10.1002/ohn.1226","url":null,"abstract":"Objective: To assess the effects of localized subglottic knockout of E-cadherin (CDH1-/-) on survival, tracheal luminal thickness, and fibrotic gene expression in a mouse model of subglottic stenosis.Study design: Case-control in vivo mouse study.Setting: Tertiary care academic hospital.Methods: Mice with loxP sites flanking E-cadherin underwent extratracheal placement of a fibrin-plasmin gel embedded with either CRE-expressing or control adenovirus. Mice then underwent chemomechanical injury to induce laryngotracheal stenosis, with harvest of subglottis/tracheas 21 days later. Immunofluorescence and Western blotting were used to confirm E-cadherin knockout. Outcomes of interest included Kaplan-Meier survival curves (n = 40), lamina propria thickness on hematoxylin-eosin (H&E) histology (n = 8), and fibrotic gene expression (n = 3).Results: Immunofluorescence and Western blotting confirmed decreased E-cadherin expression in CDH1-/-. On H&E, lamina propria thickness was greater in CDH1-/- mice (mean difference [95% CI] in μm, 107.2 [74.8-139.7], P < .001). Survival was significantly shorter for knockout mice relative to control (median survival in days, 5.0 vs 8.5; P = .007). Further, fibrotic gene expression of COL1 (mean difference [95% CI] in log-fold change, 11.5 [1.9-21.0]; P = .03), COL3 (31.0 [11.5-50.5]; P = .01), COL5 (6.8 [3.1-10.4]; P = .007), and FN1 (6.9 [1.3-12.6]; P = .03) was significantly greater relative to control.Conclusion: CDH1-/- results in greater fibrosis and increased mortality, further supporting the role of epithelial barrier dysfunction in the pathogenesis of subglottic stenosis. Therapies that restore epithelial integrity may therefore represent a rational pharmacologic target.","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"2003-2008"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12122222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suicidal Ideation, Behaviors, and Deaths in People With Ménière's Disease: A Systematic Review. 自杀意念，行为，和死亡的人与msamni<e:1>病：系统回顾。

IF 2.6 3区医学

Otolaryngology- Head and Neck Surgery Pub Date : 2025-06-01 Epub Date: 2025-03-10 DOI: 10.1002/ohn.1216

Lauren R McCray, Hannah G Farmer, Shaun A Nguyen, Jeffrey P Staab, Jacqueline P Nguyen, Jonathan Kil, Habib G Rizk

{"title":"Suicidal Ideation, Behaviors, and Deaths in People With Ménière's Disease: A Systematic Review.","authors":"Lauren R McCray, Hannah G Farmer, Shaun A Nguyen, Jeffrey P Staab, Jacqueline P Nguyen, Jonathan Kil, Habib G Rizk","doi":"10.1002/ohn.1216","DOIUrl":"10.1002/ohn.1216","url":null,"abstract":"Objective: To assess relations between Ménière's disease and suicidality, measured by suicidal ideation, suicidal behaviors, and death by suicide.Data sources: CINAHL, Cochrane Library, PubMed, PsycINFO, and SCOPUS databases were searched from inception through July 2, 2024.Review methods: Observational studies related to suicidality in patients with Ménière's disease were included. Non-English language papers, editorials, and studies on vestibular disorders not specified as Ménière's disease were excluded. The Risk Of Bias In Nonrandomized Studies-of Exposure tool was used for cohort and qualitative studies, and the Joanna Briggs Institute critical appraisal checklist was used for case-control studies.Results: Four studies (n = 168,566) were included in our review. Two cohort studies found significantly increased adjusted hazard ratios of 2.1 (95% CI: 2.0-2.2) for death by suicide and 7.6 (95% CI: 4.4-13.3) for suicidal behaviors, respectively, in patients with Ménière's disease compared to the control population after their diagnosis. However, a case-control study found no significant difference in the prevalence of suicidal ideation or behaviors prior to the date of diagnosis in patients with Ménière's disease compared to the control population (0.9% vs 0.8%; P = .44). In addition, one patient with Ménière's disease expressed suicidal ideation in the qualitative study.Conclusion: Patients may experience variable responses to Ménière's disease. Thus, otolaryngologists should be mindful of the potential for suicidality in patients with Ménière's disease.","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"1866-1873"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cochlear Implantation After Traumatic Brain Injury. 外伤性脑损伤后人工耳蜗植入。

IF 2.6 3区医学

Otolaryngology- Head and Neck Surgery Pub Date : 2025-06-01 Epub Date: 2025-03-10 DOI: 10.1002/ohn.1220

Russell W De Jong, Amanda Y Dao, James K Aden, John P Marinelli, Isaac D Erbele

{"title":"Cochlear Implantation After Traumatic Brain Injury.","authors":"Russell W De Jong, Amanda Y Dao, James K Aden, John P Marinelli, Isaac D Erbele","doi":"10.1002/ohn.1220","DOIUrl":"10.1002/ohn.1220","url":null,"abstract":"Objective: The objective of this study is to determine if a history of traumatic brain injury (TBI) degrades postoperative the audiological performance of patients with cochlear implantation (CI).Study design: Retrospective review.Setting: Department of Defense-wide database.Methods: International Classification of Diseases, Ninth Revision (ICD-9) and ICD-10 codes were used to identify patients that were diagnosed with TBI prior to CI between 2005 and 2023. They were matched 2:1 with controls without TBI based on age and sex. Preoperative and postoperative pure tone average (PTA) thresholds and AzBio scores were compared.Results: Nineteen TBI patients representing 20 implanted ears were identified and matched with 39 patients without TBI representing 40 implanted ears. Thirteen ears carried a diagnosis of mild TBI, and seven were diagnosed with moderate to severe TBI. The average follow-up period was 44 months. The TBI group attained mean postoperative PTA and AzBio scores of 37 dB (SD 24) and 67% (SD 28). The non-TBI group attained scores of 31 dB (SD 12) and 69% (SD 26). P-values for the PTA and AzBio intergroup comparisons were .93 and .88, respectively. All TBI ears attained at least sound awareness after implantation, with 79% achieving open-set speech perception compared to 82% of non-TBI ears.Conclusion: CI after TBI of any severity provides hearing rehabilitation comparable to patients without a prior diagnosis of TBI.","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"2058-2064"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Speech Performance Following Intraoperative Correction of Cochlear Implant Electrode Array Tip Fold-Overs. 人工耳蜗电极阵列尖端折叠术中矫正后的语言表现。

IF 2.6 3区医学

Otolaryngology- Head and Neck Surgery Pub Date : 2025-06-01 Epub Date: 2025-03-07 DOI: 10.1002/ohn.1199

Miriam R Smetak, Matthew A Shew, Jordan Varghese, Nedim Durakovic, Cameron C Wick, Craig A Buchman, Jacques A Herzog

{"title":"Speech Performance Following Intraoperative Correction of Cochlear Implant Electrode Array Tip Fold-Overs.","authors":"Miriam R Smetak, Matthew A Shew, Jordan Varghese, Nedim Durakovic, Cameron C Wick, Craig A Buchman, Jacques A Herzog","doi":"10.1002/ohn.1199","DOIUrl":"10.1002/ohn.1199","url":null,"abstract":"Objective: Cochlear implant (CI) electrode array tip fold-overs occur at an increased rate with perimodiolar electrode arrays, necessitating removal and re-insertion. The degree to which an intra-operative correction of tip fold-over affects CI performance and hearing preservation has not been previously reported.Study design: Retrospective chart review of CI recipients receiving a slim perimodiolar electrode array from 2016 to 2023.Setting: Tertiary referral center.Methods: Low-frequency pure tone average (LFPTA) was defined as the average of thresholds at 125, 250, and 500 Hz. We defined hearing preservation candidacy as LFPTA < 60 dB HL preoperatively, and successful hearing preservation was defined as LFPTA < 80 dB HL at activation. Consonant-nucleus-consonant (CNC) word recognition and AzBio scores in quiet and in +10 dB signal-to-noise ratio (SNR) were collected preoperatively, and at 3- and 6-months postoperatively.Results: From 663 implants, 35 (5.3%) experienced tip fold-over that was identified and corrected intra-operatively. There was no significant difference in 3-month CNC scores between those with fold-overs (44.9%, SD 20.9%) and those without (46.2%, SD 21.0%; P = .98). Similarly, there was no difference in AzBio in quiet (53.1%, SD 21.7% vs 60.8%, SD 28.0%; P = .26) or in AzBio +10 dB SNR (19.1%, SD 23.7% vs 31.5%, SD 27.2%; P = .60). Of 19 hearing preservation candidates that experienced tip fold-over, 6 (31.6%) had preserved hearing at activation compared to 31 of 59 candidates (52.5%; P = .11) without fold-over.Conclusion: While tip fold-over remains a clinical concern, speech performance does not appear to be negatively affected if the fold-over is identified and corrected.","PeriodicalId":19707,"journal":{"name":"Otolaryngology- Head and Neck Surgery","volume":" ","pages":"2046-2050"},"PeriodicalIF":2.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0