TI-RADS and Bethesda Classification System Correlate With Predicting Pediatric Papillary Thyroid Carcinoma.

IF 2.6 3区医学 Q1 OTORHINOLARYNGOLOGY

Otolaryngology- Head and Neck Surgery Pub Date : 2025-05-16 DOI:10.1002/ohn.1310

Shaunak N Amin, Megan Branson, J Nathaniel Perkins, Xing Wang, Eric C Huang, Tyler G Ketterl, Hedieh Khalatbari, Sanjay R Parikh, Scott C Manning, John P Dahl

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引用次数: 0

Abstract

Objective: Our study objectives were to evaluate the relationship between Thyroid Imaging Reporting and Data System (TI-RADS) and Bethesda classification and to compare both TI-RADS and Bethesda classification for the diagnosis of papillary thyroid carcinoma (PTC) within the pediatric population.

Study design: Retrospective case series.

Setting: Academic pediatric hospital.

Methods: A 13-year retrospective review was performed of all pediatric patients undergoing thyroid fine needle aspiration (FNA) and ultrasound at our institution. Demographics, TI-RADS scoring, FNA results, surgical history, and final pathology were collected. High-risk ultrasonography and cytopathology were defined as TI-RADS 3-5 and Bethesda 5-6, respectively. Spearman's rank correlation was determined for TI-RADS and Bethesda classification. Relative risks of high-risk TI-RADS and Bethesda classification for predicting PTC were calculated.

Results: A total of 157 patients (21.7% male, median age at time of FNA 15 years, and range 2.7-21 years) underwent ultrasound and FNA during the study. The Spearman's rank correlation coefficient for TI-RADS compared with the Bethesda classification was 0.41 (P < .001). The relative risk of high-risk TI-RADS scores to predict the presence of PTC was 7.99 (95% CI 1.16-54.90). High-risk Bethesda classification demonstrated a relative risk for predicting PTC of 6.62 (95% CI 4.22-10.41).

Conclusion: In our cohort, there was a moderate correlation between TI-RADS and Bethesda classifications. Patients with a TI-RADS score ≥3 and Bethesda classification 3 or 4 are at intermediate risk for harboring PTC and should be counseled accordingly.

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TI-RADS和Bethesda分类系统与预测儿童甲状腺乳头状癌的相关性

目的：我们的研究目的是评估甲状腺成像报告和数据系统（TI-RADS）与Bethesda分类的关系，并比较TI-RADS和Bethesda分类在儿科人群中诊断甲状腺乳头状癌（PTC）的价值。研究设计:回顾性病例系列。单位：学术儿科医院。方法：对我院所有接受甲状腺细针穿刺（FNA）和超声检查的患儿进行13年的回顾性分析。统计数据、TI-RADS评分、FNA结果、手术史和最终病理。高危超声和细胞病理学分别定义为TI-RADS 3-5和Bethesda 5-6。测定TI-RADS与Bethesda分类的Spearman等级相关性。计算高危TI-RADS的相对风险和预测PTC的Bethesda分级。结果：157例患者（21.7%男性，FNA时中位年龄15岁，范围2.7-21岁）在研究期间接受了超声和FNA。与Bethesda分类相比，TI-RADS的Spearman等级相关系数为0.41 (P)。结论：在我们的队列中，TI-RADS与Bethesda分类存在中等相关性。TI-RADS评分≥3分、Bethesda分类为3或4分的患者存在中度PTC风险，应给予相应的建议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Otolaryngology- Head and Neck Surgery 医学-耳鼻喉科学

CiteScore

6.70

自引率

2.90%

发文量

250

审稿时长

2-4 weeks

期刊介绍： Otolaryngology–Head and Neck Surgery (OTO-HNS) is the official peer-reviewed publication of the American Academy of Otolaryngology–Head and Neck Surgery Foundation. The mission of Otolaryngology–Head and Neck Surgery is to publish contemporary, ethical, clinically relevant information in otolaryngology, head and neck surgery (ear, nose, throat, head, and neck disorders) that can be used by otolaryngologists, clinicians, scientists, and specialists to improve patient care and public health.