Osteoporosis and Sarcopenia最新文献_第6页

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IF 2

Osteoporosis and Sarcopenia Pub Date : 2023-03-01 DOI: 10.1016/S2405-5255(23)00017-1

引用次数: 0

Teriparatide treatment shows faster healing than sacroplasty for postmenopausal women with sacral insufficiency fracture 特立帕肽治疗绝经后骶骨功能不全骨折比骶骨成形术愈合更快

IF 2

Osteoporosis and Sarcopenia Pub Date : 2023-03-01 DOI: 10.1016/j.afos.2023.02.001

Yao-Chun Yang , Min-Hong Hsieh , Jui-Teng Chien , Keng-Chang Liu , Chang-Chen Yang

{"title":"Teriparatide treatment shows faster healing than sacroplasty for postmenopausal women with sacral insufficiency fracture","authors":"Yao-Chun Yang , Min-Hong Hsieh , Jui-Teng Chien , Keng-Chang Liu , Chang-Chen Yang","doi":"10.1016/j.afos.2023.02.001","DOIUrl":"10.1016/j.afos.2023.02.001","url":null,"abstract":"<div><h3>Objectives</h3><p>Sacral insufficiency fracture (SIF) is not an uncommon osteoporosis fracture among the elderly. Aside from traditional treatments, sacroplasty and teriparatide (TPTD) injection have been introduced. This report aims to compare the effects of sacroplasty and teriparatide on clinical outcomes of SIF.</p></div><div><h3>Methods</h3><p>Thirty-one elderly patients with SIF were enrolled in this retrospective observational study. Four male patients were excluded. Fourteen patients who received TPTD for 6 months were classified into the TPTD group (TT), and 13 who underwent sacroplasty were classified into the sacroplasty group (SS). All patients in both groups were instructed to take calcium and vitamin D supplements daily. Their symptoms and signs, visual analog score (VAS), Oswestry disability index (ODI), and radiographic studies were retrospectively reviewed.</p></div><div><h3>Results</h3><p>The TT group showed significantly lower VAS than SS group after 3 (P < 0.001) and 6 months of treatment (P < 0.001). The TT group also has significant lower ODI than SS group after 1 (P = 0.010), 3 (P = 0.005) and 6 months (P < 0.001) of treatment. Upon generalized estimating equations (GEE) analysis, the TT group showed significantly more reduction in both VAS and ODI compared to the SS group at 1 month (P = 0.022, P = 0.001), 3 months (P < 0.001, P < 0.001), and 6 months (P < 0.001, P < 0.001) post-treatment.</p></div><div><h3>Conclusions</h3><p>Postmenoposal woman with SIF who received TPTD healed better than those who underwent sacroplasty after 1 month treatment.</p></div>","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"9 1","pages":"Pages 27-31"},"PeriodicalIF":2.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111959/pdf/main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9385454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Exploring optimal supplementation for people with vitamin D deficiency 探索维生素D缺乏症患者的最佳补充剂

IF 2

Osteoporosis and Sarcopenia Pub Date : 2023-03-01 DOI: 10.1016/j.afos.2023.03.006

Han Seok Choi

引用次数: 1

The elusive role of myostatin signaling for muscle regeneration and maintenance of muscle and bone homeostasis 肌生长抑制素信号在肌肉再生和维持肌肉和骨骼稳态中的作用

IF 2

Osteoporosis and Sarcopenia Pub Date : 2023-03-01 DOI: 10.1016/j.afos.2023.03.008

Akash Mitra , Rizwan Qaisar , Bipasha Bose , Sudheer Shenoy P

{"title":"The elusive role of myostatin signaling for muscle regeneration and maintenance of muscle and bone homeostasis","authors":"Akash Mitra , Rizwan Qaisar , Bipasha Bose , Sudheer Shenoy P","doi":"10.1016/j.afos.2023.03.008","DOIUrl":"10.1016/j.afos.2023.03.008","url":null,"abstract":"<div><p>Skeletal muscle is one of the leading frameworks of the musculo-skeletal system, which works in synergy with the bones. Long skeletal muscles provide stability and mobility to the human body and are primarily composed of proteins. Conversely, improper functioning of various skeletal muscles leads to diseases and disorders, namely, age-related muscle disorder called sarcopenia, a group of genetic muscle disorders such as muscular dystrophies, and severe muscle wasting in cancer known as cachexia. However, skeletal muscle has an excellent ability to undergo hypertrophy and enhanced functioning during sustained exercise over time. Indeed, these processes of skeletal muscle regeneration/hypertrophy, as well as degeneration and atrophy, involve an interplay of various signaling pathways. Myostatin is one such chemokine/myokine with a significant contribution to muscle regeneration or atrophy in multiple conditions. In this review, we try to put together the role and regulation of myostatin as a function of muscle regeneration extrapolated to multiple aspects of its molecular functions.</p></div>","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"9 1","pages":"Pages 1-7"},"PeriodicalIF":2.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10111947/pdf/main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9754517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Reply on “Inverse correlation of serum uric acid and relative hand grip strength in Korean adult women” 对“韩国成年女性血清尿酸与相对握力的负相关”的回复

IF 2

Osteoporosis and Sarcopenia Pub Date : 2023-03-01 DOI: 10.1016/j.afos.2023.03.005

Dongwon Yi, Min Jin Lee, Ah Reum Khang, Yang Ho Kang

引用次数: 0

Inverse correlation of serum uric acid and relative hand grip strength in Korean adult women 韩国成年女性血清尿酸与相对握力的负相关

IF 2

Osteoporosis and Sarcopenia Pub Date : 2023-03-01 DOI: 10.1016/j.afos.2023.03.002

Chang-Hee Suh

引用次数: 1

Lower SMI is a risk factor for dysphagia in Japanese hospitalized patients with osteoporotic vertebral and hip fracture: A retrospective study 低SMI是日本住院骨质疏松性椎体和髋部骨折患者吞咽困难的危险因素:一项回顾性研究

IF 2

Osteoporosis and Sarcopenia Pub Date : 2022-12-01 DOI: 10.1016/j.afos.2022.11.001

Kaoru Suseki , Masaomi Yamashita , Yoshiaki Kojima , Yojiro Minegishi , Koichiro Komiya , Masashi Takaso

{"title":"Lower SMI is a risk factor for dysphagia in Japanese hospitalized patients with osteoporotic vertebral and hip fracture: A retrospective study","authors":"Kaoru Suseki , Masaomi Yamashita , Yoshiaki Kojima , Yojiro Minegishi , Koichiro Komiya , Masashi Takaso","doi":"10.1016/j.afos.2022.11.001","DOIUrl":"10.1016/j.afos.2022.11.001","url":null,"abstract":"<div><h3>Objectives</h3><p>Many patients with osteoporotic fragile fracture often suffer from dysphagia that results in malnutrition, further deterioration of physical strength, and rehabilitation difficulties. This study aims to investigate the risk factors for dysphagia in hospitalized patients with osteoporotic vertebral and/or hip fractures.</p></div><div><h3>Methods</h3><p>Between January 2020 and December 2021, 569 inpatients were managed for osteoporotic vertebral or hip fractures. Of these, 503 patients were analyzed and 66 were excluded as the required data could not be obtained or dysphagia with causative diseases such as cerebrovascular disease. The patients were divided into 2 groups: patients with dysphagia (P-group) and patients without dysphagia (N-group). We investigated gender, fracture site, age, systemic skeletal muscle mass index (SMI), bone mineral density (BMD), and body mass index (BMI) in early stage of hospitalization and studied their relationship with dysphagia.</p></div><div><h3>Results</h3><p>There were no significant differences in gender and fracture site between the 2 groups. A significant difference was observed in age, SMI, BMD, and BMI (P < 0.01). We performed a logistic regression analysis with the P-group as the objective variable and age, SMI, BMD, and BMI as explanatory variables. We divided objective groups into all patients, patients with vertebral fracture, patients with hip fracture, men, and women. SMI was an independent risk factor in all groups.</p></div><div><h3>Conclusions</h3><p>Lower SMI was a risk factor for dysphagia in hospitalized patients with osteoporotic vertebral and hip fractures. We carefully observed swallowing function of patients with decreased SMI to maintain the nutritional status and prevent rehabilitation difficulties.</p></div>","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"8 4","pages":"Pages 152-157"},"PeriodicalIF":2.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7d/27/main.PMC9805941.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10494386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Association between serum uric acid and relative hand grip strength in comparison with metabolic syndrome components 与代谢综合征成分比较，血清尿酸和相对握力之间的关系

IF 2

Osteoporosis and Sarcopenia Pub Date : 2022-12-01 DOI: 10.1016/j.afos.2022.10.001

Dongwon Yi , Min Jin Lee , Ah Reum Khang , Yang Ho Kang

{"title":"Association between serum uric acid and relative hand grip strength in comparison with metabolic syndrome components","authors":"Dongwon Yi , Min Jin Lee , Ah Reum Khang , Yang Ho Kang","doi":"10.1016/j.afos.2022.10.001","DOIUrl":"10.1016/j.afos.2022.10.001","url":null,"abstract":"<div><h3>Objectives</h3><p>To investigate the association between serum uric acid (UA) and relative hand grip strength (HGS) in comparison with metabolic syndrome components.</p></div><div><h3>Methods</h3><p>We analyzed the data of 5247 Korean adults aged ≥ 20 years (2422 men and 2825 women) who participated in the KNHNES VII (2018).</p></div><div><h3>Results</h3><p>Among women, relative HGS was significantly lower in participants with hyperuricemia (1.65 ± 0.04) than in those without (1.95 ± 0.01) and was significantly decreased in the highest quartile (4Q: 1.77 ± 0.02) of serum UA compared with that in the lowest quartile (1Q: 1.98 ± 0.02). Among men, relative HGS was lower in participants with hyperuricemia (3.09 ± 0.04 vs. 3.16 ± 0.02) and decreased in 4Q (3.08 ± 0.03) of serum UA compared with that in 1Q (3.15 ± 0.03); however, these results were not statistically significant. In age- and multivariate-adjusted analyses in men, relative HGS was significantly lower in 4Q compared with that in 1Q in model 1 (adjusted for age), but there were no significant differences in model 2 (adjusted for age, BMI, and waist circumference) and model 3 (adjusted for age, BMI, waist circumference, systolic and diastolic blood pressure, fasting blood glucose, triglycerides, and high-density lipoprotein cholesterol). Meanwhile, in women, relative HGS was significantly decreased in 4Q compared with that in 1Q in all models.</p></div><div><h3>Conclusions</h3><p>A significant inverse correlation was observed between serum UA levels and relative HGS in women, and their significance was maintained even after adjusting for age and metabolic syndrome components.</p></div>","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"8 4","pages":"Pages 158-164"},"PeriodicalIF":2.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ca/d4/main.PMC9805934.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10489783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Nutrition in the prevention and management of sarcopenia - A special focus on Asian Indians 预防和管理肌肉减少症的营养-特别关注亚洲印度人

IF 2

Osteoporosis and Sarcopenia Pub Date : 2022-12-01 DOI: 10.1016/j.afos.2022.12.002

Shinjini Bhattacharya , Rohini Bhadra , Annemie M.W.J. Schols , Ardy van Helvoort , Sucharita Sambashivaiah

引用次数: 4

Treatment adherence and risk of vertebral fracture 治疗依从性与椎体骨折风险

IF 2

Osteoporosis and Sarcopenia Pub Date : 2022-12-01 DOI: 10.1016/j.afos.2022.11.002

Ching-Lung Cheung

引用次数: 1