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Osteoporosis and Sarcopenia最新文献

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Sclerostin's role in bone–muscle crosstalk and osteoporosis pathogenesis 硬化蛋白在骨肌串扰和骨质疏松发病中的作用
IF 2.8
Osteoporosis and Sarcopenia Pub Date : 2025-09-01 Epub Date: 2025-07-04 DOI: 10.1016/j.afos.2025.06.004
Hamzah Shahid , Vivek Kumar Morya , Kyu-Cheol Noh
{"title":"Sclerostin's role in bone–muscle crosstalk and osteoporosis pathogenesis","authors":"Hamzah Shahid ,&nbsp;Vivek Kumar Morya ,&nbsp;Kyu-Cheol Noh","doi":"10.1016/j.afos.2025.06.004","DOIUrl":"10.1016/j.afos.2025.06.004","url":null,"abstract":"<div><div>This review examines sclerostin, a critical regulator of Wnt signaling, focusing on its role in bone homeostasis and its emerging involvement in muscle–bone crosstalk. It examines the regulatory influence of hormones, mechanical stress, and myokines on sclerostin expression under both physiological and pathological conditions. Recent advances underscore sclerostin's role in osteoporosis pathogenesis and its involvement in bone remodeling, while also revealing its emerging significance in muscle–bone communication. Despite these insights, the underlying mechanisms of its regulation remain incompletely understood. By consolidating recent research, this review provides a comprehensive perspective on sclerostin's multifaceted roles and their implications for bone and muscle health.</div></div>","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"11 3","pages":"Pages 69-82"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FM - Editorial Board FM -编委会
IF 2.8
Osteoporosis and Sarcopenia Pub Date : 2025-09-01 Epub Date: 2025-09-12 DOI: 10.1016/S2405-5255(25)00117-7
{"title":"FM - Editorial Board","authors":"","doi":"10.1016/S2405-5255(25)00117-7","DOIUrl":"10.1016/S2405-5255(25)00117-7","url":null,"abstract":"","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"11 3","pages":"Page i"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reference ranges and associated factor for trabecular bone score in Vietnam: Vietnam osteoporosis study 越南骨小梁评分的参考范围和相关因素：越南骨质疏松症研究
IF 2.8
Osteoporosis and Sarcopenia Pub Date : 2025-09-01 Epub Date: 2025-09-12 DOI: 10.1016/j.afos.2025.08.018
Minh C. Doan , Lan T. Ho-Pham , Tuan V. Nguyen
{"title":"Reference ranges and associated factor for trabecular bone score in Vietnam: Vietnam osteoporosis study","authors":"Minh C. Doan ,&nbsp;Lan T. Ho-Pham ,&nbsp;Tuan V. Nguyen","doi":"10.1016/j.afos.2025.08.018","DOIUrl":"10.1016/j.afos.2025.08.018","url":null,"abstract":"","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"11 3","pages":"Page 6"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing sarcopenia screening in type 2 diabetes mellitus: A ROC curve evaluation of the SARC-F and the SARC-CalF 优化2型糖尿病肌少症筛查：SARC-F和SARC-CalF的ROC曲线评价
IF 2.8
Osteoporosis and Sarcopenia Pub Date : 2025-09-01 Epub Date: 2025-09-22 DOI: 10.1016/j.afos.2025.09.001
Shu-Ying Su , Chizimuzo T.C. Okoli , Li-Fen Chao
{"title":"Optimizing sarcopenia screening in type 2 diabetes mellitus: A ROC curve evaluation of the SARC-F and the SARC-CalF","authors":"Shu-Ying Su ,&nbsp;Chizimuzo T.C. Okoli ,&nbsp;Li-Fen Chao","doi":"10.1016/j.afos.2025.09.001","DOIUrl":"10.1016/j.afos.2025.09.001","url":null,"abstract":"<div><h3>Objectives</h3><div>Sarcopenia is highly prevalent in older adults with type 2 diabetes mellitus (T2DM), significantly increasing fall and disability risks. While the Questionnaire composed of “Strength, Assistance in walking, Rising from a chair, Climbing stairs, and Falls” (SARC-F) is commonly used for sarcopenia screening, its diagnostic accuracy in T2DM patients remains unclear. SARC-CalF, an extended version incorporating calf circumference, may enhance screening effectiveness. This study aimed to evaluate the reliability, validity, and diagnostic accuracy of SARC-F and SARC-CalF in older T2DM adults.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted with 157 T2DM patients aged 60 years and above. Sarcopenia was assessed using both SARC-F and SARC-CalF, with the 2019 Asian Working Group for Sarcopenia criteria serving as the reference standard. Collected data included demographics, muscle mass (via bioelectrical impedance analysis), muscle strength (handgrip and five-time sit-to-stand tests), and physical performance (timed up-and-go test). Reliability, validity, and diagnostic accuracy were analyzed using validated statistical techniques.</div></div><div><h3>Results</h3><div>SARC-F demonstrated good internal consistency (Cronbach's α = 0.80) and test-retest reliability (ICC = 0.89), moderate diagnostic accuracy (AUC = 0.65, 95% CI: 0.565–0.743) with an optimal cut-off score of 2.5 (sensitivity = 51.4%, specificity = 78.2%). SARC-CalF shows superior diagnostic performance (AUC = 0.98, 95% CI: 0.956–1.000 with higher sensitivity (92%) and specificity (94%).</div></div><div><h3>Conclusions</h3><div>While the SARC-F is a reliable and valid screening tool for T2DM patients, its diagnostic accuracy is limited. SARC-CalF significantly improves screening performance and is preferable for chronic care monitoring.</div></div>","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"11 3","pages":"Pages 92-97"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thai expert consensus on bone health optimization for instrumented spine surgery 泰国专家对器械脊柱手术中骨骼健康优化的共识
IF 2.8
Osteoporosis and Sarcopenia Pub Date : 2025-09-01 Epub Date: 2025-09-12 DOI: 10.1016/j.afos.2025.08.011
Weerasak Singhatanadgige MD, MSc , Thanut Valleenukul MD , Worawat Limthongkul MD , Monchai Ruangchainikom MD , Weera Chaiyamongkol MD , Roongrath Chitragran MD , Suthipas Pongmanee MD , Koopong Siribumrungwong MD , Thamrong Lertudomphonwanit MD , Vit Kotheeranurak MD , Tinnakorn Pluemvitayaporn MD , Teerachat Tanasansomboon MD , Sirinthip Petcharapiruch BPharm, MSc , Supitchaya Changsatja PharmD, MA , Wicharn Yingsakmongkol MD
{"title":"Thai expert consensus on bone health optimization for instrumented spine surgery","authors":"Weerasak Singhatanadgige MD, MSc ,&nbsp;Thanut Valleenukul MD ,&nbsp;Worawat Limthongkul MD ,&nbsp;Monchai Ruangchainikom MD ,&nbsp;Weera Chaiyamongkol MD ,&nbsp;Roongrath Chitragran MD ,&nbsp;Suthipas Pongmanee MD ,&nbsp;Koopong Siribumrungwong MD ,&nbsp;Thamrong Lertudomphonwanit MD ,&nbsp;Vit Kotheeranurak MD ,&nbsp;Tinnakorn Pluemvitayaporn MD ,&nbsp;Teerachat Tanasansomboon MD ,&nbsp;Sirinthip Petcharapiruch BPharm, MSc ,&nbsp;Supitchaya Changsatja PharmD, MA ,&nbsp;Wicharn Yingsakmongkol MD","doi":"10.1016/j.afos.2025.08.011","DOIUrl":"10.1016/j.afos.2025.08.011","url":null,"abstract":"","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"11 3","pages":"Page 4"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association between chronic kidney disease and bone mineral density 慢性肾脏疾病与骨密度的关系
IF 2.8
Osteoporosis and Sarcopenia Pub Date : 2025-09-01 Epub Date: 2025-09-12 DOI: 10.1016/j.afos.2025.08.032
Artist Suebpanich
{"title":"The association between chronic kidney disease and bone mineral density","authors":"Artist Suebpanich","doi":"10.1016/j.afos.2025.08.032","DOIUrl":"10.1016/j.afos.2025.08.032","url":null,"abstract":"","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"11 3","pages":"Page 11"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep-learning chest X-ray model for osteoporosis detection in a super-aged Hakka population 超高龄客家人骨质疏松症检测的深度学习胸片模型
IF 2.8
Osteoporosis and Sarcopenia Pub Date : 2025-09-01 Epub Date: 2025-09-12 DOI: 10.1016/j.afos.2025.08.039
Yi-Chieh Huang , Yi-Chou Chen , Ming-Te Cheng
{"title":"Deep-learning chest X-ray model for osteoporosis detection in a super-aged Hakka population","authors":"Yi-Chieh Huang ,&nbsp;Yi-Chou Chen ,&nbsp;Ming-Te Cheng","doi":"10.1016/j.afos.2025.08.039","DOIUrl":"10.1016/j.afos.2025.08.039","url":null,"abstract":"","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"11 3","pages":"Page 13"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening for osteoporosis using panoramic radiography: A three-year prospective study 利用全景x线摄影筛查骨质疏松症：一项为期三年的前瞻性研究
IF 2.8
Osteoporosis and Sarcopenia Pub Date : 2025-09-01 Epub Date: 2025-09-12 DOI: 10.1016/j.afos.2025.08.010
Akira Taguchi , Noriyuki Sugino , Hiroko Kuroiwa , Hizuru Osanai , Shinichiro Yamada , Kozue Mori , Hirokazu Kobayashi , Daisuke Higuchi , Nobuyuki Udagawa
{"title":"Screening for osteoporosis using panoramic radiography: A three-year prospective study","authors":"Akira Taguchi ,&nbsp;Noriyuki Sugino ,&nbsp;Hiroko Kuroiwa ,&nbsp;Hizuru Osanai ,&nbsp;Shinichiro Yamada ,&nbsp;Kozue Mori ,&nbsp;Hirokazu Kobayashi ,&nbsp;Daisuke Higuchi ,&nbsp;Nobuyuki Udagawa","doi":"10.1016/j.afos.2025.08.010","DOIUrl":"10.1016/j.afos.2025.08.010","url":null,"abstract":"","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"11 3","pages":"Page 4"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atypical femur fractures in Malaysia: Preliminary report from a Malaysian academic centre 马来西亚非典型股骨骨折：来自马来西亚学术中心的初步报告
IF 2.8
Osteoporosis and Sarcopenia Pub Date : 2025-09-01 Epub Date: 2025-09-12 DOI: 10.1016/j.afos.2025.08.045
Nicholas Ken Yoong Hee , Ying Guat Ooi , Terence Ong , Hui Min Khor , Jeyakantha Ratnasingam
{"title":"Atypical femur fractures in Malaysia: Preliminary report from a Malaysian academic centre","authors":"Nicholas Ken Yoong Hee ,&nbsp;Ying Guat Ooi ,&nbsp;Terence Ong ,&nbsp;Hui Min Khor ,&nbsp;Jeyakantha Ratnasingam","doi":"10.1016/j.afos.2025.08.045","DOIUrl":"10.1016/j.afos.2025.08.045","url":null,"abstract":"","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"11 3","pages":"Page 15"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic accuracy of quantitative ultrasound (QUS) for osteoporosis in medical checkups 定量超声（QUS）对骨质疏松症体检诊断的准确性
IF 2.8
Osteoporosis and Sarcopenia Pub Date : 2025-09-01 Epub Date: 2025-09-12 DOI: 10.1016/j.afos.2025.08.034
Masashi Zenta , Masahiko Bessho , Soichiro Itoh , Mayumi Hashinuma , Akira Kobayashi , Masato Namihira , Masami Yamada , Satoshi Kido , Takeru Arai
{"title":"Diagnostic accuracy of quantitative ultrasound (QUS) for osteoporosis in medical checkups","authors":"Masashi Zenta ,&nbsp;Masahiko Bessho ,&nbsp;Soichiro Itoh ,&nbsp;Mayumi Hashinuma ,&nbsp;Akira Kobayashi ,&nbsp;Masato Namihira ,&nbsp;Masami Yamada ,&nbsp;Satoshi Kido ,&nbsp;Takeru Arai","doi":"10.1016/j.afos.2025.08.034","DOIUrl":"10.1016/j.afos.2025.08.034","url":null,"abstract":"","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"11 3","pages":"Pages 11-12"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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