Osteoporosis and Sarcopenia最新文献_第8页

Effects of Teriparatide versus Vertebroplasty on pain control and radiographic outcomes after osteoporotic vertebral compression fracture 特立帕肽与椎体成形术对骨质疏松性椎体压缩性骨折后疼痛控制和影像学结果的影响

IF 2.5

Osteoporosis and Sarcopenia Pub Date : 2023-12-01 DOI: 10.1016/j.afos.2023.11.033

Chi-Chien Niu , Po-An Chen , Ping-Yeh Chiu , Fu-Cheng Kao , Ming-Kai Hsieh , Tsung-Ting Tsai , Po-Liang Lai , Tsai-Sheng Fu

引用次数: 0

The effects of integrated osteoporosis education on osteoporosis knowledge, attitude, behavior and quality of life among middle-aged and elderly osteoporosis patients 骨质疏松综合教育对中老年骨质疏松患者骨质疏松知识、态度、行为及生活质量的影响

IF 2.5

Osteoporosis and Sarcopenia Pub Date : 2023-12-01 DOI: 10.1016/j.afos.2023.11.028

I-Chin Huang , Chih-Lung Lin , Hsiu-Hung Wang

引用次数: 0

Comparison of refracture and mortality of forearm fracture in middle-aged and elderly people with or without combination of traditional Chinese and western medicine 中西医结合与非中西医结合治疗中老年人前臂骨折的再骨折率及死亡率比较

IF 2.5

Osteoporosis and Sarcopenia Pub Date : 2023-12-01 DOI: 10.1016/j.afos.2023.11.041

Ching-Feng Cho , Chia-Chun Li , Ta-Wei Tai , Ching-Ju Chiu , Chih-Hsing Wu

引用次数: 0

Musculoskeletal and neurocognitive clinical significance of adult hypophosphatasia 成人低磷酸盐症的肌肉骨骼和神经认知临床意义

IF 2.5

Osteoporosis and Sarcopenia Pub Date : 2023-12-01 DOI: 10.1016/j.afos.2023.12.003

Se-Min Kim, Funda Korkmaz, Steve Sims, Vitaly Ryu, Tony Yuen, Mone Zaidi

{"title":"Musculoskeletal and neurocognitive clinical significance of adult hypophosphatasia","authors":"Se-Min Kim, Funda Korkmaz, Steve Sims, Vitaly Ryu, Tony Yuen, Mone Zaidi","doi":"10.1016/j.afos.2023.12.003","DOIUrl":"10.1016/j.afos.2023.12.003","url":null,"abstract":"<div><div>Hypophosphatasia (HPP), also called Rathbun disease, is a rare genetic disorder that is caused by the loss-of-function mutation in the <em>ALPL</em> gene encoding tissue non-specific alkaline phosphatase. Doctor Rathbun first described the case of a 3-week-old infant who presented with severe osteopenia, rickets, and multiple radiographic fractures, and died shortly after of epileptic seizure and respiratory distress. The term “hypophosphatasia” was coined as the patients’ alkaline phosphatase levels were significantly low. Since then, our understanding of HPP has evolved, and now we appreciate causative genetic mutation and the broad spectrum of clinical presentation depending on the age of onset, severity, and skeletal involvement: perinatal, infantile, childhood, adult and odontohypophosphatasia. The new development of enzyme replacement with asfostase alfa has saved the lives of severe form of hypophosphatasia. However, it is still unclear and remains challenging how to manage adult HPP that often presents with mild and non-specific symptoms such as muscle pain, joint stiffness, fatigue, anxiety, or low bone mass, which are common in the general population and not necessarily attributed to HPP. In this review, we will present 3 unique cases of adult HPP and discuss the pathophysiology, clinical presentation particularly neuromuscular and neurocognitive symptoms and management of adult HPP.</div></div>","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"9 4","pages":"Pages 115-120"},"PeriodicalIF":2.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139015335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment persistence and medication switch associated with subsequent fractures after osteoporotic fractures 治疗持续性和药物转换与骨质疏松性骨折后的后续骨折相关

IF 2.5

Osteoporosis and Sarcopenia Pub Date : 2023-12-01 DOI: 10.1016/j.afos.2023.11.005

Sung-Yen Lin , Yi-Ming Chen , Li-Nien Chien , Chung-Hwan Chen

引用次数: 0

Osteoporosis case manager intervention to improve medication possession ratio among osteoporotic patients with anti-osteoporotic medication for fragility fracture 骨质疏松症病例管理员干预提高脆性骨折抗骨质疏松症患者药物持有率

IF 2.5

Osteoporosis and Sarcopenia Pub Date : 2023-12-01 DOI: 10.1016/j.afos.2023.11.024

Chia-Tien Hsu , Ya-Lien Teng , Shih-Yi Lin , Hsu-Tung Lee

引用次数: 0

Bone mineral metabolism and different indices of skeletal health of Ladakhi women living at high altitude 生活在高海拔地区的拉达克妇女的骨矿物质代谢和骨骼健康的不同指数

IF 2.5

Osteoporosis and Sarcopenia Pub Date : 2023-12-01 DOI: 10.1016/j.afos.2023.11.001

Lijy K. Babu, Snigdha Shaw, Dishari Ghosh

{"title":"Bone mineral metabolism and different indices of skeletal health of Ladakhi women living at high altitude","authors":"Lijy K. Babu, Snigdha Shaw, Dishari Ghosh","doi":"10.1016/j.afos.2023.11.001","DOIUrl":"10.1016/j.afos.2023.11.001","url":null,"abstract":"<div><h3>Objectives</h3><div>High altitude possesses a great challenge for human survival owing to low oxygen tension and has been reported to cause bone deterioration among sojourns of high altitude. The bone health of Ladakhi women is investigated for the first time in this study.</div></div><div><h3>Methods</h3><div>Dual energy X-ray absorptiometry of Ladakhi women and sea level women was done at the radius and calcaneus using EXA-3000 (Osteosys, Korea), followed by colorimetric and Enzyme Linked Immunosorbent Assay analysis of parameters regulating bone health.</div></div><div><h3>Results</h3><div>There was no statistically significant difference between bone mineral density of Ladakhi women and sea level women at radius (P = 0.287) or calcaneus (P = 0.839). Almost similar cases of osteopenia were reported at both sites measured in the study among both groups. Two post-menopausal Ladakhi women however, had osteoporosis at the radius while 4 had osteoporosis at calcaneus. Significant increase in calcium levels with a decrease in intact parathyroid hormone and an increase in calcitonin levels were observed in Ladakhi women as compared to sea level women. Though there was no significant difference in 25-hydroxy vitamin D levels of both groups, a higher percentage of 25-hydroxy vitamin D deficiency (77% <em>vs</em> 23%) was observed in Ladakhi women as compared to sea level women. Estradiol levels were similar in both groups.</div></div><div><h3>Conclusions</h3><div>The present study suggest that there is no significant relationship between high altitude living and bone mineral density among Ladakhi women.</div></div>","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"9 4","pages":"Pages 131-136"},"PeriodicalIF":2.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139305641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pain score as a predictor of subsequent fragility fracture in postmenopausal patients with rheumatoid arthritis: A retrospective case-control study 疼痛评分是绝经后类风湿性关节炎患者发生脆性骨折的预测因素：一项回顾性病例对照研究

IF 2.5

Osteoporosis and Sarcopenia Pub Date : 2023-12-01 DOI: 10.1016/j.afos.2023.12.001

Ichiro Yoshii , Naoya Sawada , Tatsumi Chijiwa

{"title":"Pain score as a predictor of subsequent fragility fracture in postmenopausal patients with rheumatoid arthritis: A retrospective case-control study","authors":"Ichiro Yoshii , Naoya Sawada , Tatsumi Chijiwa","doi":"10.1016/j.afos.2023.12.001","DOIUrl":"10.1016/j.afos.2023.12.001","url":null,"abstract":"<div><h3>Objectives</h3><div>Bone fragility fracture (BFF) is a serious incident in treating rheumatoid arthritis (RA). We hypothesized that pain degree during treatment RA correlated with incident BFF and validated how pain affects incident BFF (inc-BFF).</div></div><div><h3>Methods</h3><div>Postmenopausal RA patients treated for at least 3 years were recruited. The primary endpoint was the development of inc-BFF. Follow-up began with the first bone mineral density measurement (baseline) and continued until the development of the first BFF or termination of the study. Clinical indicators at baseline, including pain score using a visual analog scale (PS-VAS), were analyzed statistically using Cox regression analysis, receiver operation characteristics (ROC), Kaplan-Meier survival curve analysis (K-M), and chi-square test.</div></div><div><h3>Results</h3><div>A total of 239 patients were recruited. Using a multivariate Cox regression analysis, the baseline's PS-VAS and prevalent BFF (pr-BFF) demonstrated significantly higher risk ratios. For ROC, pr-BFF and PS-VAS had significant cutoff index (COI) (positive, 21.0) and an area under-curve of 0.692 (P < 0.001) and 0.616 (P < 0.01), respectively. PS-VAS > COI had a 2.24-fold higher hazard ratio than PS-VAS ≤ COI using K-M. When these 2 conditions were combined, patients with pr-BFF-positive and PS-VAS-positive had a sensitivity of 42.3% and a specificity of 88.8% for the inc-BFF. PS-VAS > COI had no statistical significance in the subgroup without pr-BFF, whereas the existence of pr-BFF had a significantly higher risk ratio in the PS-VAS ≤ COI.</div></div><div><h3>Conclusions</h3><div>The PS-VAS during RA treatment is a good indicator for predicting the inc-BFF in postmenopausal RA patients with pr-BFF.</div></div>","PeriodicalId":19701,"journal":{"name":"Osteoporosis and Sarcopenia","volume":"9 4","pages":"Pages 150-156"},"PeriodicalIF":2.5,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139014638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CYP2C19 genotypes and osteoporotic fractures in long-term users of proton pump inhibitors: A hospital-based study CYP2C19基因型与长期使用质子泵抑制剂的骨质疏松性骨折：一项基于医院的研究

IF 2.5

Osteoporosis and Sarcopenia Pub Date : 2023-12-01 DOI: 10.1016/j.afos.2023.11.018

Chun-Sheng Hsu , Yi-Ming Chen , Yi-Ju Liao

引用次数: 0

Risk factors for mortality, fractures and falls among patients participating in a Fracture Liaison Service program: a machine learning approach 参与骨折联络服务项目的患者死亡率、骨折和跌倒的危险因素：机器学习方法

IF 2.5

Osteoporosis and Sarcopenia Pub Date : 2023-12-01 DOI: 10.1016/j.afos.2023.11.010

Christina Soong , Hsuan-Yu Chen , Feng-Huei Lin , Tsung-Han Yang , Rong-Sen Yang , Chih-Hao Chang , Ding-Cheng Chan

引用次数: 0