OTO Open最新文献

{"title":"Machine Learning Predicts 30-Day Readmission and Mortality After Surgical Resection of Head and Neck Cancer.","authors":"Daniel Fu, Aman M Patel, Lucy Revercomb, Andrey Filimonov, Ghayoour S Mir","doi":"10.1002/oto2.70100","DOIUrl":"10.1002/oto2.70100","url":null,"abstract":"<p><strong>Objective: </strong>To develop and validate a machine learning model to identify patients at high risk of 30-day mortality and hospital readmission using routinely collected health care data.</p><p><strong>Study design: </strong>Prognostic predictive modeling and retrospective cohort study. The study was conducted in 2024 using data from 2006 to 2018, with at least a 30-day follow-up.</p><p><strong>Setting: </strong>The 2006 to 2018 National Cancer Database (NCDB).</p><p><strong>Methods: </strong>The study used deidentified NCDB data on 103,891 head and neck squamous cell carcinoma (HNSCC) patients who underwent surgical resection. Machine learning models were trained on 80% of the data, tested on the remaining 20%, and evaluated using the area under the curve (AUC) and SHapley Additive exPlanations (SHAP) analysis to identify key predictors for 30-day mortality and readmission.</p><p><strong>Results: </strong>Among 103,891 patients, 5838 (5.6%) were readmitted, and 829 (0.8%) died within 30 days. The median age was 62, 69% male, and 89% white. Predictors included demographic and clinical data from the NCDB. Five machine learning models were combined and achieved an AUC of 0.80 (95% CI: 0.77-0.83) for mortality prediction and 0.67 (95% CI: 0.65-0.68) for readmission prediction. SHAP analysis identified sex and urban-rural index as key predictors of mortality and readmission, respectively.</p><p><strong>Conclusion: </strong>Machine learning models can accurately predict mortality and readmission risks, offering insights into the most influential factors. With further validation, these models may enhance clinical decision-making in postsurgical care for HNSCC patients.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70100"},"PeriodicalIF":1.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Candidacy for Unilateral Hypoglossal Nerve Stimulation Without Drug-Induced Sleep Endoscopy.","authors":"Samuel Tschopp, Urs Borner, Marco Caversaccio, Kurt Tschopp","doi":"10.1002/oto2.70099","DOIUrl":"10.1002/oto2.70099","url":null,"abstract":"<p><strong>Objective: </strong>Patients undergo a drug-induced sleep endoscopy before unilateral hypoglossal nerve stimulation. This study aims to reduce the need for preoperative drug-induced sleep endoscopy by predicting favorable collapse patterns at the velum based on clinical examination and sleep study data.</p><p><strong>Study design: </strong>A retrospective cohort study.</p><p><strong>Setting: </strong>A single-center trial.</p><p><strong>Methods: </strong>Drug-induced sleep endoscopy recordings were scored by a blinded rater, and the palatal collapse pattern was classified as favorable (no or anterior-posterior) or unfavorable (lateral or concentric), irrespective of collapse degree. Logistic regression models were constructed using clinical examination and sleep data to predict palatal collapse patterns. Model performance was assessed using receiver-operating characteristic curves and validated internally using bootstrapping and externally using a separate cohort.</p><p><strong>Results: </strong>Recordings of 250 patients were analyzed, of which 118 showed a favorable palatal collapse pattern. Lower body mass index (BMI), lower tonsil grade, and less intense bed-partner-reported snoring were significant predictors of favorable collapse patterns (area under the curve [AUC] 0.70). A further reduction in tonsil grade and BMI resulted in similar model performance (AUC 0.68). In patients with no tonsils and BMI < 28 kg/m² or tonsil grade 1 and BMI < 24 kg/m², a favorable collapse was correctly predicted in 81%. In external validation, favorable collapse was correctly identified in 91%.</p><p><strong>Conclusion: </strong>Favorable palatal collapse can accurately be predicted in patients with small or absent tonsils and low BMI. Before unilateral hypoglossal nerve stimulation implantation, a drug-induced sleep endoscopy might not be necessary in this subset of patients.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70099"},"PeriodicalIF":1.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and Evaluation of a Novel Open-Source 3D Printed Simulator for Microlaryngeal Surgery.","authors":"Alan Balu, Hemali P Shah, Sagar Vasandani, Nazaneen Grant","doi":"10.1002/oto2.70098","DOIUrl":"10.1002/oto2.70098","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the feasibility and utility of a novel, open-source 3D printed simulator for practicing laryngeal surgery skills in the clinic setting.</p><p><strong>Study design: </strong>Device development and validation.</p><p><strong>Setting: </strong>A tertiary medical center.</p><p><strong>Methods: </strong>A laryngeal surgery simulator was created using computer-aided design software and 3D printed. Ten otolaryngology residents completed exercises utilizing the simulator and a flexible video laryngoscope for visualization. The training involved 3 microsurgery tasks: (1) suture removal from simulated vocal cords, (2) removal of silicone vocal cord polyps, and (3) simulated flap creation by peeling a grape's skin. Participant demographics, task completion time, and video recordings were collected. Participants provided subjective feedback through 5-point Likert-style questions assessing content and face validity.</p><p><strong>Results: </strong>Both novice and experienced otolaryngology resident physicians reported positive perceptions of the simulator and its efficacy as an educational device, with average agreement more than neutral (<i>P</i> < .01). Participants praised the simulator's utility for practicing microsurgery skills using a flexible video laryngoscope and for handling instruments such as Kleinsasser forceps and micro scissors (<i>P</i> < .01). Preliminary findings suggest improvements in task completion time with higher post-graduate year. Participants also reported the need for greater realism.</p><p><strong>Conclusion: </strong>This study of a 3D-printed simulator for laryngeal surgery skills using a flexible video laryngoscope demonstrated promising utility as an educational device. Positive feedback reflects the potential value as a training tool for residents to practice fine motor skills required for laryngeal surgery. Further research with larger sample sizes is needed to validate these findings.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70098"},"PeriodicalIF":1.8,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Head and Neck Cancer Symptoms and Risk Factors Awareness and Effectiveness of Educational Intervention for Underserved Populations.","authors":"Jad F Zeitouni, Jyntre Millsap, Harry May, Wooyoung Jang, Yusuf Dundar","doi":"10.1002/oto2.70089","DOIUrl":"10.1002/oto2.70089","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate head and neck cancer (HNC) risk factors and symptoms (RFS) awareness, human papillomavirus (HPV) vaccination rates, and socioeconomic factors among an underserved population at a community free clinic, and to implement an adaptable educational intervention to address low awareness of HNC RFS.</p><p><strong>Study design: </strong>Cross-sectional survey.</p><p><strong>Setting: </strong>Community Free Clinic.</p><p><strong>Methods: </strong>We surveyed patients participating in HNC screenings including their knowledge of HNC RFS, HPV vaccination status, patient demographics, and other pertinent questions. After the initial survey, volunteers used public available infographics by the Head and Neck Cancer Alliance to educate participants about HNC. A post-screening survey assessed short-term retention and understanding.</p><p><strong>Results: </strong>Fifty-nine participants were included. Most had limited knowledge of HNC risk factors and symptoms, except for tobacco use. Only 11.9% were HPV-vaccinated, including 6.25% of 27-45-year-olds; 30% of participants had not heard about HPV and an additional 23.3% did not know a vaccine existed. Most participants were low-income, with 86.2% making under $50,000 a year (58.6% making under $25,000). Participants reported insurance status (42.3%) and other costs (25.8%) as barriers to seeking HNC screening. The education intervention significantly improved participants' ability to identify symptoms and risk factors (<i>P</i> < .0001 for all surveyed items), including HPV as a risk factor (<i>P</i> < .0001).</p><p><strong>Conclusion: </strong>Our intervention successfully improved short-term knowledge of HNC RFS. The study revealed low HNC awareness, HPV awareness, and HPV vaccination rates among eligible, at-risk patients. This study outlines an implementable intervention to address low HNC awareness in underserved populations.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70089"},"PeriodicalIF":1.8,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Quality Improvement Initiative to Reduce Opioid Use Following Routine Thyroid and Parathyroid Surgery.","authors":"Jordan West, Nathan Boyd, Antoinette Esce, Garth Olson","doi":"10.1002/oto2.70096","DOIUrl":"10.1002/oto2.70096","url":null,"abstract":"<p><strong>Objective: </strong>Evaluate the postoperative pain management of patients at a single institution following routine thyroid and parathyroid surgery and compare patient opioid use before and after a practice wide quality improvement change.</p><p><strong>Study design: </strong>Retrospective chart review with prospective survey administration.</p><p><strong>Setting: </strong>University of New Mexico Hospital.</p><p><strong>Methods: </strong>A standardized perioperative pain management protocol was implemented for patients undergoing routine thyroid or parathyroid surgery. Quality assurance surveys about pain and medication use following surgery were given to patients treated after the standardized protocol was introduced. Univariate and multivariate analysis was performed. Descriptive statistics and qualitative thematic analysis of survey responses were used to analyze survey results.</p><p><strong>Results: </strong>A standardized pain management routine reduced opioid prescriptions by 46.6% for routine thyroid and parathyroid surgery patients (20.2% vs 11.0%, <i>P</i> < .01). On multivariate logistic regression, receiving education about pain at discharge (OR 0.37, <i>P</i> < 0.05) and older age (OR 0.97, <i>P</i> < .01) were associated with fewer opioid prescriptions while anxiety (OR 2.77, <i>P</i> < .05) and drain placement (4.61, <i>P</i> < .001) were associated with more opioid prescriptions. About half of surveyed patients completed at least one postoperative questionnaire, and most patients complained of headache, fatigue, or sore throat as opposed to pain at the surgical site.</p><p><strong>Conclusion: </strong>Standardized counseling about postoperative pain, including clear expectations and adjunctive measures, reduces the need for postoperative opioid prescriptions in patients undergoing routine thyroid and parathyroid surgery.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70096"},"PeriodicalIF":1.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Cisplatin on Hearing: Analysis Using PTA, High-Frequency Audiometry, DPOAE, and Speech-in-Noise Test.","authors":"Juhi Irfana Basheer, Ramaswamy Balakrishnan, Poorvi V Sharma, Madikeri Mohan Kishan, Karthik Udupa","doi":"10.1002/oto2.70097","DOIUrl":"10.1002/oto2.70097","url":null,"abstract":"<p><strong>Objective: </strong>To assess hearing loss in patients with cancer receiving cisplatin-based chemotherapy using high-frequency pure tone average (HFPTA), distortion product otoacoustic emissions (DPOAEs), and the speech-in-noise (SPIN) test, and to identify associated factors.</p><p><strong>Study design: </strong>Prospective study.</p><p><strong>Setting: </strong>Tertiary care hospital.</p><p><strong>Methods: </strong>Patients scheduled for cisplatin chemotherapy were included in the study. Audiological assessments, including HFPTA, DPOAE, and SPIN tests, were conducted at baseline, after two cycles, and after four cycles of chemotherapy. Clinical data were also analyzed.</p><p><strong>Results: </strong>One-third of the population was aged between 51 and 60 years. Higher cumulative doses of cisplatin were administered for bladder and head and neck cancers, reaching up to 3200 mg over four cycles. Most patients had normal hearing at baseline, but HFPTA detected significant hearing loss at various frequencies (8-20 kHz) over follow-ups. DPOAE showed increased negative emissions over time. A weak, negative correlation between cisplatin dose and extended high-frequency audiometry (maximum -0.311 at 18 kHz) and DPOAE (maximum -0.173 at 1500 Hz) was observed. The SPIN test suggested reduced SPIN performance with treatment progression. However, correlation with cisplatin doses was not statistically significant.</p><p><strong>Conclusion: </strong>The study underscores the importance of integrated audiological monitoring in detecting early ototoxicity in cisplatin-treated patients, emphasizing the need for periodic auditory assessments during chemotherapy. SPIN test is a simple tool offering significant potential for ototoxicity monitoring.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70097"},"PeriodicalIF":1.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Speech and Swallowing Dysfunction and Intervention Among Individuals With Myasthenia Gravis.","authors":"Tyler J Gallagher, Chloe Santa Maria, Michael M Johns","doi":"10.1002/oto2.70077","DOIUrl":"10.1002/oto2.70077","url":null,"abstract":"<p><strong>Objective: </strong>To examine the prevalence of dysphonia and dysphagia among individuals with myasthenia gravis (MG) and the frequency of utilization of speech and swallow evaluation and therapy.</p><p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>TriNetX US Collaborative Network.</p><p><strong>Methods: </strong>The cohort includes adults (≥18 years) with and without MG diagnosis. Propensity score matching was used before generating odds ratios (OR) of receiving speech and swallow diagnoses including dysarthria, dysphonia, dysphagia, and aspiration pneumonia. Subsequently, rates of individuals with MG receiving voice and swallow evaluation and therapy were analyzed.</p><p><strong>Results: </strong>In this cohort, the prevalence of voice, speech, and swallowing pathology was higher in those with MG than without, including aspiration pneumonia (3.7% vs 0.7%), dysarthria (9.2% vs 0.5%), dysphonia (4.4% vs 1.2%), and dysphagia (24.9% vs 4.7%). ORs for diagnosis of each type of pathology were higher after MG diagnosis, including for aspiration pneumonia (OR: 2.69 [95% confidence interval, CI: 1.95-3.70]), dysarthria (OR: 9.28 [95% CI: 6.67-12.92]), dysphonia (OR: 2.63 [95% CI: 1.97-3.53]), and dysphagia (OR: 4.18 [95% CI: 3.62-4.83]). Finally, the rate of receiving a swallow and/or voice evaluation and/or therapy was low among all individuals with MG (16.9%) but higher among those with MG with any speech or swallow symptom (47.0%), MG with dysarthria and/or dysphonia (56.2%), and MG with dysphagia and/or aspiration pneumonia (49.0%).</p><p><strong>Conclusion: </strong>Rates of dysarthria, dysphonia, dysphagia, and aspiration pneumonia were far more common among those with MG than without, but formal speech and/or swallow evaluation was not routine. These findings suggest a need for more routine speech-language pathology evaluation among individuals with MG.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70077"},"PeriodicalIF":1.8,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11880630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Diagnostic Concordance of Low-cost Endoscopic Remote Consultation Versus Standard Otolaryngology Evaluation.","authors":"Manuela Restrepo Peláez, Paola Herrera Noreña, Tania Margarita Salgado Gómez, Ingri Julieth Patiño Ariza, Carlos Stiven Zúñiga Bravo, Sebastián Orozco Arteaga","doi":"10.1002/oto2.70072","DOIUrl":"10.1002/oto2.70072","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the diagnostic concordance between findings obtained using a low-cost endoscope during telepresence evaluations and those obtained through conventional otolaryngology consultations.</p><p><strong>Study design: </strong>An observational cross-sectional study was conducted between September 2022 and October 2023.</p><p><strong>Setting: </strong>Second-level clinic providing in-person otolaryngology consultations for patients aged 18 and older.</p><p><strong>Methods: </strong>A total of 223 evaluations were performed on 217 adult patients, comparing in-person assessments with remote evaluations using a low-cost otoendoscopic device. Diagnostic concordance was assessed for 7 otolaryngological conditions: tympanic perforation, myringosclerosis, signs of external otitis, middle ear effusion, turbinate hypertrophy, septal deviation, and tonsillar hypertrophy. Statistical analysis included the calculation of Cohen's <i>κ</i> coefficient and diagnostic performance measures.</p><p><strong>Results: </strong>The endoscopic evaluation demonstrated high diagnostic concordance for ear and oral cavity assessments, particularly for tympanic perforation and signs of external otitis (<i>κ</i> of 1 and 0.93, respectively). Conversely, low concordance was observed for nasal findings such as turbinate hypertrophy and septal deviation (<i>κ</i> of 0.07 and 0.11, respectively). Limitations in image resolution and data capture of the low-cost device were identified.</p><p><strong>Conclusion: </strong>The low-cost endoscope used in telepresence otolaryngology consultations is effective for evaluating ear and oral cavity findings but shows limitations in nasal cavity assessments. Telemedicine in otolaryngology can reduce health care access barriers in settings with limited availability of specialized services. This study underscores the need for continued research and development of more precise diagnostic devices in otolaryngology.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70072"},"PeriodicalIF":1.8,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11880627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public Knowledge and Factors Associated With Familiarity of Treatments for Rhinosinusitis.","authors":"Tyler J Gallagher, Rishabh Shah, Michelle Koh, Catherine Julien, Matthew E Lin, Kevin Hur","doi":"10.1002/oto2.70091","DOIUrl":"https://doi.org/10.1002/oto2.70091","url":null,"abstract":"<p><strong>Objective: </strong>Rhinosinusitis is a common otolaryngologic condition with many over-the-counter (OTC), prescription, and surgical treatment options. This study seeks to evaluate public familiarity with treatments for rhinosinusitis.</p><p><strong>Study design: </strong>Cross-sectional survey.</p><p><strong>Setting: </strong>US adult (≥18 years) online survey respondents.</p><p><strong>Methods: </strong>A cross-sectional survey was administered to US adults via ResearchMatch. Questions included a demographic questionnaire, validated nasal obstruction surveys, personal history of chronic rhinosinusitis (CRS), as well as familiarity with various treatments for rhinosinusitis (5-point Likert scale). Descriptive statistics were utilized to describe results, and multivariable ordinal regression was utilized to describe factors associated with knowledge of any treatment and over-the-counter treatments.</p><p><strong>Results: </strong>The cohort (n = 1086) was primarily female (75.7%), white (80.3%), married (47.5%), and college educated (36.6%). Highest rates of familiarity with treatment were reported for antihistamines (80%), decongestants (80%), and nasal corticosteroids (78%). Factors associated with knowledge of any rhinosinusitis treatment included age (odds ratio [OR]: 0.99 [95% confidence interval [CI]: 0.98-0.99]), literacy score (OR: 0.76 [95% CI: 0.71-0.82]), CRS diagnosis (OR: 2.91 [95% CI: 2.25-3.75]), and symptomatic score. Factors associated with knowledge of OTC treatments included female gender (OR: 2.40 [95% CI: 1.82-3.16]), literacy score (OR: 0.77 [95% CI: 0.72-0.83]), CRS diagnosis (OR: 2.94 [95% CI: 2.25-3.83]), and symptomatic score.</p><p><strong>Conclusion: </strong>Individuals at risk for having lower familiarity with treatment options include males, older individuals, and those with lower health literacy. Future studies should evaluate the impact that public knowledge and primary care provider knowledge of treatment options for rhinosinusitis has on outcomes of rhinosinusitis.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70091"},"PeriodicalIF":1.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11868991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemophilic Pseudotumor Arising in Buccal Space Presenting as Rapidly Progressive Facial Swelling: A Diagnostic Dilemma.","authors":"Asimakis D Asimakopoulos, Eugène Panosetti","doi":"10.1002/oto2.70081","DOIUrl":"https://doi.org/10.1002/oto2.70081","url":null,"abstract":"","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70081"},"PeriodicalIF":1.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11868697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}