OTO Open最新文献

Reducing Glove Overuse in Outpatient Specialty Clinics: Cost Reduction and Environmental Benefit.

IF 1.8

OTO Open Pub Date : 2025-03-27 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70103

M Lauren Lalakea, Julia E Noel, Duncan A Meiklejohn

引用次数: 0

Fibrin Sealants in Facial Plastic Surgery: A National Database Analysis of Complication Risk.

IF 1.8

OTO Open Pub Date : 2025-03-26 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70102

Hänel W Eberly, Sandeep Pradhan, Jacqueline Tucker, Bao Y Sciscent, Tonya S King, Jessyka G Lighthall

{"title":"Fibrin Sealants in Facial Plastic Surgery: A National Database Analysis of Complication Risk.","authors":"Hänel W Eberly, Sandeep Pradhan, Jacqueline Tucker, Bao Y Sciscent, Tonya S King, Jessyka G Lighthall","doi":"10.1002/oto2.70102","DOIUrl":"10.1002/oto2.70102","url":null,"abstract":"Objective: Fibrin sealants (FS) are gaining popularity in surgical practice. However, limited data exist for most facial plastic surgical (FPS) procedures.Study design: Retrospective cohort.Setting: The TriNetX Research Network.Methods: The TriNetX national database was utilized to identify patients that underwent select FPS procedures. Cohorts included one group with FS recorded on the same day as the procedure, and another without. Demographics, comorbidities, and postoperative complications were investigated.Results: A total of 550,777 patients underwent an FPS procedure, 600 patients with FS and 550,177 without. There was no difference in the rate of overall complications between groups (adjusted odds ratio [aOR] 0.92, [0.71-1.2], P = .54), with adjustment for age, race, ethnicity, marital status, nicotine use, and anticoagulation. However, higher rates of postoperative wound disruption (aOR 1.63, [1.14-2.33], P = .008) were seen in the FS group. Patients in the FS group had higher rates of nicotine use (12.7% vs 8.7%, P < .001) and anticoagulation (39.2% vs 27.7%, P < .001) overall. Subanalyses by procedure found increased rates of any postoperative complications for those with FS (aOR 1.51, [1.01-2.24], P = .044) in patients receiving regional flaps. There were no significant differences in postoperative complications between groups in patients receiving grafts, rhinoplasty, or rhytidectomy.Conclusion: There were no differences in the rates of having any complications between groups overall. Patients receiving regional flaps and grafts experienced more complications. There were no significant differences between groups in patients receiving grafts, rhinoplasty, or rhytidectomy. Surgeons may consider utilizing FS for FPS procedures when appropriate.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70102"},"PeriodicalIF":1.8,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143720936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictors of Decision to Pursue Sleep Surgery.

IF 1.8

OTO Open Pub Date : 2025-03-26 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70093

Tiffany Husman, Amrita Bhat, Megan L Durr, Jolie L Chang

{"title":"Predictors of Decision to Pursue Sleep Surgery.","authors":"Tiffany Husman, Amrita Bhat, Megan L Durr, Jolie L Chang","doi":"10.1002/oto2.70093","DOIUrl":"10.1002/oto2.70093","url":null,"abstract":"Objective: To identify predictors of patient decision to pursue sleep apnea surgery following initial consultation with a sleep surgeon.Study design: Retrospective cohort analysis.Setting: Outpatient tertiary care academic center.Methods: A retrospective review of patients with obstructive sleep apnea (OSA) diagnosis, BMI < 35 kg/m², and prior positive airway pressure (PAP) trial who were evaluated at a sleep surgery clinic. Patients who completed drug-induced sleep endoscopy (DISE) and/or surgery were compared to those who did not within at least 4 months of consultation. Surveys on OSA-related symptoms and decisional conflict were completed prior to the consultation for PAP alternatives.Results: Among 437 patients, 321 did not undergo DISE/surgery, whereas 116 completed DISE/surgery within an average of 16.8 months of consultation. Patients who underwent DISE/surgery had a significantly higher Epworth sleepiness scale score (10.1 ± 4.9 vs 8.5 ± 5.1, P = .006) and insomnia severity index (15.6 ± 5.5 vs 14.3 ± 5.8, P = .037) as well as significantly lower decisional conflict scale (DCS) scores (27.9 ± 21.8 vs 38.2 ± 24.9, P < .001). Multivariate analysis revealed that lower preconsultation DCS score (OR = 0.97, 95% CI [0.97, 0.99], P < .001) and lower BMI (OR = 0.91, 95% CI [0.85, 0.99], P = .019) were independently significant predictors of pursuing DISE/surgery.Conclusion: Decisional conflict prior to consultation is significantly associated with completion of DISE/surgery. Those with higher decisional conflict are less likely to proceed with DISE/surgery after consultation on PAP alternatives. Effective interventions that improve patient understanding of OSA and enhance support in decision-making are needed.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70093"},"PeriodicalIF":1.8,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143720937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Machine Learning Predicts 30-Day Readmission and Mortality After Surgical Resection of Head and Neck Cancer.

IF 1.8

OTO Open Pub Date : 2025-03-20 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70100

Daniel Fu, Aman M Patel, Lucy Revercomb, Andrey Filimonov, Ghayoour S Mir

{"title":"Machine Learning Predicts 30-Day Readmission and Mortality After Surgical Resection of Head and Neck Cancer.","authors":"Daniel Fu, Aman M Patel, Lucy Revercomb, Andrey Filimonov, Ghayoour S Mir","doi":"10.1002/oto2.70100","DOIUrl":"10.1002/oto2.70100","url":null,"abstract":"Objective: To develop and validate a machine learning model to identify patients at high risk of 30-day mortality and hospital readmission using routinely collected health care data.Study design: Prognostic predictive modeling and retrospective cohort study. The study was conducted in 2024 using data from 2006 to 2018, with at least a 30-day follow-up.Setting: The 2006 to 2018 National Cancer Database (NCDB).Methods: The study used deidentified NCDB data on 103,891 head and neck squamous cell carcinoma (HNSCC) patients who underwent surgical resection. Machine learning models were trained on 80% of the data, tested on the remaining 20%, and evaluated using the area under the curve (AUC) and SHapley Additive exPlanations (SHAP) analysis to identify key predictors for 30-day mortality and readmission.Results: Among 103,891 patients, 5838 (5.6%) were readmitted, and 829 (0.8%) died within 30 days. The median age was 62, 69% male, and 89% white. Predictors included demographic and clinical data from the NCDB. Five machine learning models were combined and achieved an AUC of 0.80 (95% CI: 0.77-0.83) for mortality prediction and 0.67 (95% CI: 0.65-0.68) for readmission prediction. SHAP analysis identified sex and urban-rural index as key predictors of mortality and readmission, respectively.Conclusion: Machine learning models can accurately predict mortality and readmission risks, offering insights into the most influential factors. With further validation, these models may enhance clinical decision-making in postsurgical care for HNSCC patients.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70100"},"PeriodicalIF":1.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predicting Candidacy for Unilateral Hypoglossal Nerve Stimulation Without Drug-Induced Sleep Endoscopy.

IF 1.8

OTO Open Pub Date : 2025-03-20 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70099

Samuel Tschopp, Urs Borner, Marco Caversaccio, Kurt Tschopp

{"title":"Predicting Candidacy for Unilateral Hypoglossal Nerve Stimulation Without Drug-Induced Sleep Endoscopy.","authors":"Samuel Tschopp, Urs Borner, Marco Caversaccio, Kurt Tschopp","doi":"10.1002/oto2.70099","DOIUrl":"10.1002/oto2.70099","url":null,"abstract":"Objective: Patients undergo a drug-induced sleep endoscopy before unilateral hypoglossal nerve stimulation. This study aims to reduce the need for preoperative drug-induced sleep endoscopy by predicting favorable collapse patterns at the velum based on clinical examination and sleep study data.Study design: A retrospective cohort study.Setting: A single-center trial.Methods: Drug-induced sleep endoscopy recordings were scored by a blinded rater, and the palatal collapse pattern was classified as favorable (no or anterior-posterior) or unfavorable (lateral or concentric), irrespective of collapse degree. Logistic regression models were constructed using clinical examination and sleep data to predict palatal collapse patterns. Model performance was assessed using receiver-operating characteristic curves and validated internally using bootstrapping and externally using a separate cohort.Results: Recordings of 250 patients were analyzed, of which 118 showed a favorable palatal collapse pattern. Lower body mass index (BMI), lower tonsil grade, and less intense bed-partner-reported snoring were significant predictors of favorable collapse patterns (area under the curve [AUC] 0.70). A further reduction in tonsil grade and BMI resulted in similar model performance (AUC 0.68). In patients with no tonsils and BMI < 28 kg/m2 or tonsil grade 1 and BMI < 24 kg/m2, a favorable collapse was correctly predicted in 81%. In external validation, favorable collapse was correctly identified in 91%.Conclusion: Favorable palatal collapse can accurately be predicted in patients with small or absent tonsils and low BMI. Before unilateral hypoglossal nerve stimulation implantation, a drug-induced sleep endoscopy might not be necessary in this subset of patients.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70099"},"PeriodicalIF":1.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility and Evaluation of a Novel Open-Source 3D Printed Simulator for Microlaryngeal Surgery.

IF 1.8

OTO Open Pub Date : 2025-03-10 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70098

Alan Balu, Hemali P Shah, Sagar Vasandani, Nazaneen Grant

{"title":"Feasibility and Evaluation of a Novel Open-Source 3D Printed Simulator for Microlaryngeal Surgery.","authors":"Alan Balu, Hemali P Shah, Sagar Vasandani, Nazaneen Grant","doi":"10.1002/oto2.70098","DOIUrl":"10.1002/oto2.70098","url":null,"abstract":"Objective: This study aims to evaluate the feasibility and utility of a novel, open-source 3D printed simulator for practicing laryngeal surgery skills in the clinic setting.Study design: Device development and validation.Setting: A tertiary medical center.Methods: A laryngeal surgery simulator was created using computer-aided design software and 3D printed. Ten otolaryngology residents completed exercises utilizing the simulator and a flexible video laryngoscope for visualization. The training involved 3 microsurgery tasks: (1) suture removal from simulated vocal cords, (2) removal of silicone vocal cord polyps, and (3) simulated flap creation by peeling a grape's skin. Participant demographics, task completion time, and video recordings were collected. Participants provided subjective feedback through 5-point Likert-style questions assessing content and face validity.Results: Both novice and experienced otolaryngology resident physicians reported positive perceptions of the simulator and its efficacy as an educational device, with average agreement more than neutral (P < .01). Participants praised the simulator's utility for practicing microsurgery skills using a flexible video laryngoscope and for handling instruments such as Kleinsasser forceps and micro scissors (P < .01). Preliminary findings suggest improvements in task completion time with higher post-graduate year. Participants also reported the need for greater realism.Conclusion: This study of a 3D-printed simulator for laryngeal surgery skills using a flexible video laryngoscope demonstrated promising utility as an educational device. Positive feedback reflects the potential value as a training tool for residents to practice fine motor skills required for laryngeal surgery. Further research with larger sample sizes is needed to validate these findings.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70098"},"PeriodicalIF":1.8,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Head and Neck Cancer Symptoms and Risk Factors Awareness and Effectiveness of Educational Intervention for Underserved Populations.

IF 1.8

OTO Open Pub Date : 2025-03-07 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70089

Jad F Zeitouni, Jyntre Millsap, Harry May, Wooyoung Jang, Yusuf Dundar

{"title":"Head and Neck Cancer Symptoms and Risk Factors Awareness and Effectiveness of Educational Intervention for Underserved Populations.","authors":"Jad F Zeitouni, Jyntre Millsap, Harry May, Wooyoung Jang, Yusuf Dundar","doi":"10.1002/oto2.70089","DOIUrl":"10.1002/oto2.70089","url":null,"abstract":"Objective: To evaluate head and neck cancer (HNC) risk factors and symptoms (RFS) awareness, human papillomavirus (HPV) vaccination rates, and socioeconomic factors among an underserved population at a community free clinic, and to implement an adaptable educational intervention to address low awareness of HNC RFS.Study design: Cross-sectional survey.Setting: Community Free Clinic.Methods: We surveyed patients participating in HNC screenings including their knowledge of HNC RFS, HPV vaccination status, patient demographics, and other pertinent questions. After the initial survey, volunteers used public available infographics by the Head and Neck Cancer Alliance to educate participants about HNC. A post-screening survey assessed short-term retention and understanding.Results: Fifty-nine participants were included. Most had limited knowledge of HNC risk factors and symptoms, except for tobacco use. Only 11.9% were HPV-vaccinated, including 6.25% of 27-45-year-olds; 30% of participants had not heard about HPV and an additional 23.3% did not know a vaccine existed. Most participants were low-income, with 86.2% making under $50,000 a year (58.6% making under $25,000). Participants reported insurance status (42.3%) and other costs (25.8%) as barriers to seeking HNC screening. The education intervention significantly improved participants' ability to identify symptoms and risk factors (P < .0001 for all surveyed items), including HPV as a risk factor (P < .0001).Conclusion: Our intervention successfully improved short-term knowledge of HNC RFS. The study revealed low HNC awareness, HPV awareness, and HPV vaccination rates among eligible, at-risk patients. This study outlines an implementable intervention to address low HNC awareness in underserved populations.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70089"},"PeriodicalIF":1.8,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Quality Improvement Initiative to Reduce Opioid Use Following Routine Thyroid and Parathyroid Surgery.

IF 1.8

OTO Open Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70096

Jordan West, Nathan Boyd, Antoinette Esce, Garth Olson

{"title":"A Quality Improvement Initiative to Reduce Opioid Use Following Routine Thyroid and Parathyroid Surgery.","authors":"Jordan West, Nathan Boyd, Antoinette Esce, Garth Olson","doi":"10.1002/oto2.70096","DOIUrl":"10.1002/oto2.70096","url":null,"abstract":"Objective: Evaluate the postoperative pain management of patients at a single institution following routine thyroid and parathyroid surgery and compare patient opioid use before and after a practice wide quality improvement change.Study design: Retrospective chart review with prospective survey administration.Setting: University of New Mexico Hospital.Methods: A standardized perioperative pain management protocol was implemented for patients undergoing routine thyroid or parathyroid surgery. Quality assurance surveys about pain and medication use following surgery were given to patients treated after the standardized protocol was introduced. Univariate and multivariate analysis was performed. Descriptive statistics and qualitative thematic analysis of survey responses were used to analyze survey results.Results: A standardized pain management routine reduced opioid prescriptions by 46.6% for routine thyroid and parathyroid surgery patients (20.2% vs 11.0%, P < .01). On multivariate logistic regression, receiving education about pain at discharge (OR 0.37, P < 0.05) and older age (OR 0.97, P < .01) were associated with fewer opioid prescriptions while anxiety (OR 2.77, P < .05) and drain placement (4.61, P < .001) were associated with more opioid prescriptions. About half of surveyed patients completed at least one postoperative questionnaire, and most patients complained of headache, fatigue, or sore throat as opposed to pain at the surgical site.Conclusion: Standardized counseling about postoperative pain, including clear expectations and adjunctive measures, reduces the need for postoperative opioid prescriptions in patients undergoing routine thyroid and parathyroid surgery.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70096"},"PeriodicalIF":1.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Cisplatin on Hearing: Analysis Using PTA, High-Frequency Audiometry, DPOAE, and Speech-in-Noise Test. 顺铂对听力的影响：利用 PTA、高频测听、DPOAE 和噪声语音测试进行分析

IF 1.8

OTO Open Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70097

Juhi Irfana Basheer, Ramaswamy Balakrishnan, Poorvi V Sharma, Madikeri Mohan Kishan, Karthik Udupa

{"title":"Impact of Cisplatin on Hearing: Analysis Using PTA, High-Frequency Audiometry, DPOAE, and Speech-in-Noise Test.","authors":"Juhi Irfana Basheer, Ramaswamy Balakrishnan, Poorvi V Sharma, Madikeri Mohan Kishan, Karthik Udupa","doi":"10.1002/oto2.70097","DOIUrl":"10.1002/oto2.70097","url":null,"abstract":"Objective: To assess hearing loss in patients with cancer receiving cisplatin-based chemotherapy using high-frequency pure tone average (HFPTA), distortion product otoacoustic emissions (DPOAEs), and the speech-in-noise (SPIN) test, and to identify associated factors.Study design: Prospective study.Setting: Tertiary care hospital.Methods: Patients scheduled for cisplatin chemotherapy were included in the study. Audiological assessments, including HFPTA, DPOAE, and SPIN tests, were conducted at baseline, after two cycles, and after four cycles of chemotherapy. Clinical data were also analyzed.Results: One-third of the population was aged between 51 and 60 years. Higher cumulative doses of cisplatin were administered for bladder and head and neck cancers, reaching up to 3200 mg over four cycles. Most patients had normal hearing at baseline, but HFPTA detected significant hearing loss at various frequencies (8-20 kHz) over follow-ups. DPOAE showed increased negative emissions over time. A weak, negative correlation between cisplatin dose and extended high-frequency audiometry (maximum -0.311 at 18 kHz) and DPOAE (maximum -0.173 at 1500 Hz) was observed. The SPIN test suggested reduced SPIN performance with treatment progression. However, correlation with cisplatin doses was not statistically significant.Conclusion: The study underscores the importance of integrated audiological monitoring in detecting early ototoxicity in cisplatin-treated patients, emphasizing the need for periodic auditory assessments during chemotherapy. SPIN test is a simple tool offering significant potential for ototoxicity monitoring.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70097"},"PeriodicalIF":1.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881013/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of Speech and Swallowing Dysfunction and Intervention Among Individuals With Myasthenia Gravis.

IF 1.8

OTO Open Pub Date : 2025-03-04 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70077

Tyler J Gallagher, Chloe Santa Maria, Michael M Johns

{"title":"Prevalence of Speech and Swallowing Dysfunction and Intervention Among Individuals With Myasthenia Gravis.","authors":"Tyler J Gallagher, Chloe Santa Maria, Michael M Johns","doi":"10.1002/oto2.70077","DOIUrl":"10.1002/oto2.70077","url":null,"abstract":"Objective: To examine the prevalence of dysphonia and dysphagia among individuals with myasthenia gravis (MG) and the frequency of utilization of speech and swallow evaluation and therapy.Study design: Retrospective cohort study.Setting: TriNetX US Collaborative Network.Methods: The cohort includes adults (≥18 years) with and without MG diagnosis. Propensity score matching was used before generating odds ratios (OR) of receiving speech and swallow diagnoses including dysarthria, dysphonia, dysphagia, and aspiration pneumonia. Subsequently, rates of individuals with MG receiving voice and swallow evaluation and therapy were analyzed.Results: In this cohort, the prevalence of voice, speech, and swallowing pathology was higher in those with MG than without, including aspiration pneumonia (3.7% vs 0.7%), dysarthria (9.2% vs 0.5%), dysphonia (4.4% vs 1.2%), and dysphagia (24.9% vs 4.7%). ORs for diagnosis of each type of pathology were higher after MG diagnosis, including for aspiration pneumonia (OR: 2.69 [95% confidence interval, CI: 1.95-3.70]), dysarthria (OR: 9.28 [95% CI: 6.67-12.92]), dysphonia (OR: 2.63 [95% CI: 1.97-3.53]), and dysphagia (OR: 4.18 [95% CI: 3.62-4.83]). Finally, the rate of receiving a swallow and/or voice evaluation and/or therapy was low among all individuals with MG (16.9%) but higher among those with MG with any speech or swallow symptom (47.0%), MG with dysarthria and/or dysphonia (56.2%), and MG with dysphagia and/or aspiration pneumonia (49.0%).Conclusion: Rates of dysarthria, dysphonia, dysphagia, and aspiration pneumonia were far more common among those with MG than without, but formal speech and/or swallow evaluation was not routine. These findings suggest a need for more routine speech-language pathology evaluation among individuals with MG.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70077"},"PeriodicalIF":1.8,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11880630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0