OTO Open最新文献_第10页

Characteristics of the Facial Canal-Lateral Canal Dehiscence: The Under-recognized Third Window. 面侧管破裂的特征：未被认识的第三个窗口。

IF 1.8

OTO Open Pub Date : 2025-02-17 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70085

William J Garvis, Blake A Johnson, Katherine E Kluesner, Stephanie M Garvis

{"title":"Characteristics of the Facial Canal-Lateral Canal Dehiscence: The Under-recognized Third Window.","authors":"William J Garvis, Blake A Johnson, Katherine E Kluesner, Stephanie M Garvis","doi":"10.1002/oto2.70085","DOIUrl":"10.1002/oto2.70085","url":null,"abstract":"Objective: We aimed to establish normative data on the bony partition between the facial canal (FC) and the lateral semicircular canal (LSCC) and present our initial series of cases in which an FC-LSCC dehiscence was identified based on these anatomic criteria, with or without other third window pathologies.Study design: Normative data: Analysis of archival otopathological human temporal bone specimens and computed tomography (CT) scans. Clinical data: Case studies.Setting: An otopathology laboratory and a specialized otolaryngology, head and neck surgery outpatient clinic.Methods: We measured the bony partition thickness between the FC-LSCC in human temporal bone otopathological specimens and CT scans. The clinical study involved a series of reviews of patients with FC-LSCC, presenting clinical data and CT images.Results: The average thickness of the bony partition measured via CT was 0.6 mm ± 0.2 mm, whereas in otopathological specimens it was 0.56 mm ± 0.17 mm. We identified 34 patients with FC-LSCC dehiscence. The most frequently reported symptoms were hearing loss (44%), dizziness/vertigo (44%), and tinnitus (41%). Of the patients, 15 (44%) had more than 1 site of bone dehiscence and 21 (62%) had bilateral FC-LSCC dehiscence. We then identified 36 patients in whom only FC-LSCC dehiscences were found and provided characteristics for this population.Conclusion: Our study provides normative characteristics on the bony partition between the FC-LSCC and the signs and symptoms of this third window abnormality. FC-LSCC should be included in differential diagnoses of patients presenting with third window syndrome symptoms.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70085"},"PeriodicalIF":1.8,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11831756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacteriome of the Middle Ear in Children and Young Adults With Cholesteatoma and Retraction Pocket: A Pilot Study. 儿童和青少年胆脂瘤和内陷袋中耳细菌群：一项初步研究。

IF 1.8

OTO Open Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70051

Michal Bartos, Milan Urik, Lucie Buresova, Pavla Holochova, Eva Budinska, Petra Borilova Linhartova

{"title":"Bacteriome of the Middle Ear in Children and Young Adults With Cholesteatoma and Retraction Pocket: A Pilot Study.","authors":"Michal Bartos, Milan Urik, Lucie Buresova, Pavla Holochova, Eva Budinska, Petra Borilova Linhartova","doi":"10.1002/oto2.70051","DOIUrl":"10.1002/oto2.70051","url":null,"abstract":"Objective: Chronic otitis media (COM) is a common middle ear disease in children and young adults. Dysfunction of the Eustachian tube and bacterial infection are the main causes. This pilot study aimed to describe and compare bacteriomes of the middle ear in children and young adults with serious forms of COM, such as cholesteatoma and retraction pocket (RP) of the tympanic membrane, with bacteriomes in healthy middle ears.Study design: Observational study.Setting: Clinical practice in a tertiary center. From January 1, 2021 to August 31, 2022. Patients aged 0 to 20 years.Methods: In this case-control study, middle ears were swabbed during surgery on children with cholesteatoma (N = 23) or RP (N = 26) and on children indicated for cochlear implant (N = 15, controls). Genomic DNA extraction was followed by creation of a 16S ribosomal DNA gene library and sequencing on a MiSeq instrument. Samples with relative abundance of at least one bacterial genus >20% were considered positive for the specific genus.Results: Bacterial diversity was generally low in the middle ear samples from patients with COM, with DNA content from 1 or 2 bacteria usually dominating in the sample. A significant difference in positivity for one or more bacterial genera was observed between patients with cholesteatoma or RP (38.8%) versus patients indicated for cochlear implants (6.7%).Conclusion: While middle ear bacteriomes in cases of cholesteatoma and RP differed from those of controls, findings in the 2 pathological conditions were similar. These results support the statement that the RP could be a precholesteatoma stage.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70051"},"PeriodicalIF":1.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effective Treatment for Choanal Atresia Using Laser and Steroid Stents: A Case Report. 激光联合类固醇支架有效治疗后肛门闭锁1例报告。

IF 1.8

OTO Open Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70082

Haoran Huang, Lijun Xu, Yinyan Lai, Haocheng Tang

引用次数: 0

Comparing Low-Frequency Hearing Thresholds between Insert Earphones and Headphones in Ears with Tympanic Membrane Perforations. 耳膜穿孔时插入式耳机与耳机低频听力阈值的比较。

IF 1.8

OTO Open Pub Date : 2025-02-12 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70045

Anna Hsu, Sarah H Al Nemer, Peter Kfoury, Jordan Stout, Anna Holley, Caitlin Stone, Matthew Firpo, Albert Park

{"title":"Comparing Low-Frequency Hearing Thresholds between Insert Earphones and Headphones in Ears with Tympanic Membrane Perforations.","authors":"Anna Hsu, Sarah H Al Nemer, Peter Kfoury, Jordan Stout, Anna Holley, Caitlin Stone, Matthew Firpo, Albert Park","doi":"10.1002/oto2.70045","DOIUrl":"10.1002/oto2.70045","url":null,"abstract":"Objective: To compare hearing thresholds at 250 and 500 Hz in pediatric patients with tympanic membrane perforations (TMP) using RadioEar IP30 insert earphones and RadioEar TDH50s 3045 supra-aural headphones.Study design: Prospective clinical pilot study.Setting: Primary Children's Hospital, Utah.Methods: Children (<18 years of age) were prospectively enrolled into 2 groups based on the presence of TMPs (no TMP, TMP). Hearing thresholds were measured at 250 and 500 Hz using RadioEar IP30 insert earphones and RadioEar TDH50s 3045 supra-aural headphones for all participants.Results: At 250 and 500 Hz, hearing thresholds were significantly higher when recorded with insert earphones than with supra-aural headphones in pediatric participants with TMPs. At 250 Hz, thresholds obtained with inserts were 14.7 ± 7.2 dB (P < .001) higher than thresholds obtained with supra-aural headphones and 8.0 ± 7.5 dB higher (P < .01) at 500 Hz.Conclusion: Low-frequency hearing thresholds were significantly higher when measured with insert earphones in patients with TMPsbut not in patients without TMPs. A diagnosis of low-frequency hearing loss must be interpreted with caution when using insert earphones in participants with TMPs.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70045"},"PeriodicalIF":1.8,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11815708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143409988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining the Obstacles to Timely Otolaryngology Care in Ethiopia and Zimbabwe: A Comparative Analysis. 检查障碍及时耳鼻喉科护理在埃塞俄比亚和津巴布韦：比较分析。

IF 1.8

OTO Open Pub Date : 2025-02-07 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70078

Daniel G Eyassu, Estephania Candelo, Katerina J Green, Katherine P Wallerius, Brhanu H Asgedom, Joshua P Wiedermann

{"title":"Examining the Obstacles to Timely Otolaryngology Care in Ethiopia and Zimbabwe: A Comparative Analysis.","authors":"Daniel G Eyassu, Estephania Candelo, Katerina J Green, Katherine P Wallerius, Brhanu H Asgedom, Joshua P Wiedermann","doi":"10.1002/oto2.70078","DOIUrl":"10.1002/oto2.70078","url":null,"abstract":"This study compares delays in otolaryngologic care between patients in Mekelle, Ethiopia and Harare, Zimbabwe using the Three Delays model. Patient surveys conducted among 46 patients in Zimbabwe during October 2022 and 105 patients in Ethiopia during June 2023 revealed a significantly higher prevalence of delays in seeking and reaching care in Ethiopia. This was in the aftermath of the Tigray War, which damaged the region's health care infrastructure and diminished the trust of patients. In Zimbabwe, there was poor awareness among patients and nonotolaryngologist providers of otolaryngology disease and care capacity leading to delays in seeking and reaching care. Patients in both countries faced delays in receiving appropriate care due to resource limitations, with Ethiopia's constraints worsened by the recent war and Zimbabwe's by consistent health care underfunding. The longest delays were observed in head and neck oncology care. These findings provide a foundation for understanding otolaryngologic care delays in these low- and middle-income countries.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70078"},"PeriodicalIF":1.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11803452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delivery of Timely Adjuvant Radiation Among Veterans With Head and Neck Cancer. 头颈癌退伍军人的及时辅助放疗。

IF 1.8

OTO Open Pub Date : 2025-02-06 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70037

Jasmine Gulati, Anuja Shah, Veranca Shah, Thomas Haupt, Amanda Walsh, Jessica H Maxwell

{"title":"Delivery of Timely Adjuvant Radiation Among Veterans With Head and Neck Cancer.","authors":"Jasmine Gulati, Anuja Shah, Veranca Shah, Thomas Haupt, Amanda Walsh, Jessica H Maxwell","doi":"10.1002/oto2.70037","DOIUrl":"10.1002/oto2.70037","url":null,"abstract":"Objective: The objective of this study was to determine the rate at which veterans with head and neck squamous cell carcinoma (HNSCC) received care adhering to National Comprehensive Care Network (NCCN) guidelines for postoperative radiation and to identify factors associated with non-adherence. The guidelines recommend initiation of postoperative radiation therapy (PORT) within 6 weeks of surgery.Study design: This was a retrospective cohort analysis of a pre-existing database.Setting: This study, performed at the DC Veterans Affairs Medical Center, identified patients with HNSCC who underwent surgery with curative intent followed by adjuvant radiation ± chemotherapy between 1991 and 2021.Methods: Variables assessed included patient demographics, cancer stage and site, treatment type, dates of treatment initiation and completion, and adherence to the NCCN guidelines for PORT initiation. Fisher exact test was used to identify factors associated with delays >6 weeks.Results: Among the 132 veterans identified, 72 (54.5%) underwent surgery followed by adjuvant PORT. Only 18 veterans (25%) started radiation within 6 weeks of surgery. Patients who underwent a neck dissection at the time of the index surgery (P = .028), dental extraction (P = .032), or gastrostomy tube placement (P = .041) were more likely to experience delays.Conclusion: Only 25% of veterans initiated PORT within 6 weeks. Identifying causes of delays provides an important step in addressing discrepancies between guideline-directed care and actual care delivered. Development of efficient care pathways to increase guideline-congruent initiation of PORT should be considered.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70037"},"PeriodicalIF":1.8,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11800129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differences in Negotiated Facility Fees for Otolaryngology Procedures at Ambulatory Surgery Centers and Hospitals. 门诊手术中心和医院耳鼻喉科手术协商设施费用的差异。

IF 1.8

OTO Open Pub Date : 2025-01-31 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70086

Anika S Walia, Roy Xiao, Daphne T Hao, Vinay K Rathi, Rosh K V Sethi, Stacey T Gray

引用次数: 0

Olfactory Dysfunction in Primary Ciliary Dyskinesia. 原发性纤毛运动障碍的嗅觉功能障碍。

IF 1.8

OTO Open Pub Date : 2025-01-31 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70084

Zainab Farzal, Kelli M Sullivan, Maimoona A Zariwala, Brian D Thorp, Brent A Senior, Charles S Ebert, Stephanie Davis, Margaret W Leigh, Michael R Knowles, Adam J Kimple

{"title":"Olfactory Dysfunction in Primary Ciliary Dyskinesia.","authors":"Zainab Farzal, Kelli M Sullivan, Maimoona A Zariwala, Brian D Thorp, Brent A Senior, Charles S Ebert, Stephanie Davis, Margaret W Leigh, Michael R Knowles, Adam J Kimple","doi":"10.1002/oto2.70084","DOIUrl":"10.1002/oto2.70084","url":null,"abstract":"Objective: Individuals with primary ciliary dyskinesia (PCD) frequently report olfactory dysfunction, yet this deficit is poorly documented. The purpose of this study was to characterize the presence and degree of olfactory dysfunction in PCD compared to controls and determine whether certain PCD genes are associated with worse olfaction.Study design: A prospective cohort study.Setting: Tertiary referral center.Methods: We administered the University of Pennsylvania Smell Identification Test (UPSIT) to individuals with PCD. Participants were divided into 3 age groups (15-29 years, 30-44 years, and 45+ years) and compared to age- and sex-matched normal controls (n = 2170).Results: Twenty-nine individuals with PCD (8 males and 21 females) met the criteria (median age: 38 years; interquartile range: 22-47). Only 27.6% of patients with PCD had UPSIT scores within the normosmia range. The UPSIT median scores of each PCD age group were significantly lower than the median scores of the controls (P < .0001 for each age group). UPSIT scores generally worsened with age: mean 33 (mild hyposmia) for 15 to 29 years, 26.8 (moderate hyposmia) for 30 to 44 years, and 20.9 (severe hyposmia) for 45+ years. The most common genes coded were absent inner dynein arm/microtubule disorientation (IDA/MTD) defect (11/24, 45.8%), followed by absent outer dynein arm defect (8/24, 33.3%). The CCDC39 gene (IDA/MTD) was associated with worse olfactory dysfunction.Conclusion: Individuals with PCD have a substantially higher prevalence and degree of olfactory dysfunction compared to age-matched controls. Our study is the first to report greater olfactory dysfunction with age in PCD patients, highlighting an important area for research.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70084"},"PeriodicalIF":1.8,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11783683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concurrent Nasal Symptoms in Non-Rhinogenic Headache. 非鼻源性头痛并发鼻症状

IF 1.8

OTO Open Pub Date : 2025-01-27 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70083

David W Jang, Avivah J Wang, Ralph Abi Hachem, Bradley J Goldstein, David L Witsell, Frederick Godley, Rong Jiang

{"title":"Concurrent Nasal Symptoms in Non-Rhinogenic Headache.","authors":"David W Jang, Avivah J Wang, Ralph Abi Hachem, Bradley J Goldstein, David L Witsell, Frederick Godley, Rong Jiang","doi":"10.1002/oto2.70083","DOIUrl":"10.1002/oto2.70083","url":null,"abstract":"Objective: This study aims to characterize concurrent nasal symptoms in a cohort of patients with non-rhinogenic headache (NRH) presenting to an otolaryngology clinic.Study design: A prospective cohort.Setting: Single tertiary care institution.Methods: Adults with NRH were recruited over a 2-year period (February 2021 to February 2023). Patients were eligible if they endorsed midfacial pain or pressure for at least 10 days a month over the previous 3 months and had no evidence of rhinosinusitis on both nasal endoscopy and computed tomography imaging. Study participants used a mobile application to keep a daily log of their facial pain/pressure, nasal congestion, and nasal mucus/discharge. Symptom severity was scored on a scale from 1 (none) to 10 (worst) for 30 consecutive days. Repeated measures correlation coefficients were calculated to evaluate overall or common intra-individual association for each symptom.Results: Twenty-eight patients were enrolled, and they completed the 30-day symptom log. Median (range) scores were 5 (1-10), 4 (1-10), and 2 (1-10) for facial pain/pressure, congestion, and mucus, respectively. Patients had significant day-to-day fluctuations in scores for all 3 symptoms, with a significant positive correlation between symptoms: congestion/mucus (r = 0.74181, P < .0001), congestion/facial pain (r = 0.5873, P = .001), and mucus/facial pain (r = 0.49384, P = .0076).Conclusion: Patients with NRH often have concurrent nasal symptoms. Moreover, nasal congestion, mucus, and facial pain/pressure had significant correlations in day-to-day fluctuations in severity. Our findings suggest the possibility that all three symptoms share a common pathophysiology.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70083"},"PeriodicalIF":1.8,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Efficacy and Outcomes of Electro-Pneumatic Intracorporeal Lithotripsy in the Management of Sialolithiasis. 电气压体外碎石术治疗涎石症的临床疗效及预后。

IF 1.8

OTO Open Pub Date : 2025-01-26 eCollection Date: 2025-01-01 DOI: 10.1002/oto2.70080

Iulian Filipov, Lucian Chirila, Mihai Sandulescu, Gheorghe Cristache, Corina Marilena Cristache

{"title":"Clinical Efficacy and Outcomes of Electro-Pneumatic Intracorporeal Lithotripsy in the Management of Sialolithiasis.","authors":"Iulian Filipov, Lucian Chirila, Mihai Sandulescu, Gheorghe Cristache, Corina Marilena Cristache","doi":"10.1002/oto2.70080","DOIUrl":"10.1002/oto2.70080","url":null,"abstract":"Objective: This study aims to evaluate the clinical efficacy of electro-pneumatic intracorporeal lithotripsy for the treatment of salivary gland stones.Study design: A prospective cohort study of patients diagnosed with obstructive salivary gland syndrome, where basket-assisted sialendoscopy alone failed to remove the calculi.Setting: This study was conducted at the \"Queen Maria\" Military Hospital in Brașov, Romania, and a private practice, between February 2023 and May 2024.Methods: A total of 29 patients with salivary calculi were treated using the SialoLither device (Hidromed), which operates on the electro-pneumatic principle. The number of sessions required for complete stone removal, the duration of each session, and the number of ballistic impulses applied were recorded. Statistical analyses, including the Mann-Whitney U test and multiple linear regression, were conducted to assess the relationship between stone size, location, and treatment outcomes.Results: Complete removal was achieved in 72.4% of patients after a single session, with 100% success after 3 sessions. The average number of impulses was 13.9 (±4.25), with no significant difference in outcomes between the parotid and submandibular glands (P > .05). The total duration varied, with a mean time of 89.97 (±54.89) minutes. Complications were minimal, with only 2 cases of minor epithelial damage.Conclusion: Electro-pneumatic intracorporeal lithotripsy is a highly effective, minimally invasive technique for managing salivary calculi, offering a safe and efficient alternative to traditional surgical methods.","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"9 1","pages":"e70080"},"PeriodicalIF":1.8,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11764989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0