OTO Open最新文献

{"title":"Demographics of Adults With Obstructive Sleep Apnea Who Undergo Nasal Surgery.","authors":"Swapnil Shah, Jeanne A Darbinian, Samuel A Collazo, Dang Khoa Nguyen, Megan L Durr","doi":"10.1002/oto2.70005","DOIUrl":"https://doi.org/10.1002/oto2.70005","url":null,"abstract":"<p><strong>Objective: </strong>To assess the demographic characteristics between adult obstructive sleep apnea (OSA) patients who did and did not undergo nasal surgery (NS).</p><p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Kaiser Permanente Northern California clinical database.</p><p><strong>Methods: </strong>Retrospective study of adult patients with ≥1 OSA diagnoses linked to clinical encounters from 2009 to 2016. Qualifying NS procedures performed on or after cohort entry through 2017 were ascertained. Demographic and clinical characteristics were compared; multivariable logistic regression examined associations of these characteristics with undergoing NS.</p><p><strong>Results: </strong>A total of 174,821 patients had an OSA diagnosis. Among these, 3518 (2.0%) underwent NS, including septoplasty (61.9%), sinus-related (12.9%), turbinate (14.2%), and rhinoplasty (11.1%) procedures. Compared to the nonsurgery group, NS patients were more likely to be male (75.5% vs 62.1%), younger (48.2 ± 13.0 vs 54.7 ± 14.1), have lower body mass index (31.8 ± 6.4 vs 34.3 ± 8.1), and no comorbid conditions (63.1% vs 53.5%), <i>P</i> < .001. After adjusting for sex, age, body mass index (BMI), neighborhood deprivation, and comorbidities, black and Asian/Pacific Islander adults with OSA had 42% and 46% decreased odds of undergoing NS compared with non-Hispanic white patients (odds ratio, OR [95% confidence interval, CI]: 0.58 [0.50-0.67] and 0.54 [0.49-0.61]), while Hispanic patients had similar odds (OR [95% CI]: 1.02 [0.93-1.12]). Patients living in neighborhoods of highest deprivation had 18% lower odds of undergoing NS, compared with patients from neighborhoods corresponding to areas of lowest deprivation (adjusted odds ratio [95% CI]: 0.82 [0.75-0.91]).</p><p><strong>Conclusion: </strong>These findings suggest that younger age, male sex, lower BMI, and higher SES may be associated with a higher likelihood of undergoing NS in OSA patients.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e70005"},"PeriodicalIF":1.8,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11405934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142292851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating ChatGPT as a Patient Education Tool for COVID-19-Induced Olfactory Dysfunction.","authors":"Elliott M Sina, Daniel J Campbell, Alexander Duffy, Shreya Mandloi, Peter Benedict, Douglas Farquhar, Aykut Unsal, Gurston Nyquist","doi":"10.1002/oto2.70011","DOIUrl":"https://doi.org/10.1002/oto2.70011","url":null,"abstract":"<p><strong>Objective: </strong>While most patients with COVID-19-induced olfactory dysfunction (OD) recover spontaneously, those with persistent OD face significant physical and psychological sequelae. ChatGPT, an artificial intelligence chatbot, has grown as a tool for patient education. This study seeks to evaluate the quality of ChatGPT-generated responses for COVID-19 OD.</p><p><strong>Study design: </strong>Quantitative observational study.</p><p><strong>Setting: </strong>Publicly available online website.</p><p><strong>Methods: </strong>ChatGPT (GPT-4) was queried 4 times with 30 identical questions. Prior to questioning, Chat-GPT was \"prompted\" to respond (1) to a patient, (2) to an eighth grader, (3) with references, and (4) no prompt. Answer accuracy was independently scored by 4 rhinologists using the Global Quality Score (GCS, range: 1-5). Proportions of responses at incremental score thresholds were compared using <i>χ</i> ² analysis. Flesch-Kincaid grade level was calculated for each answer. Relationship between prompt type and grade level was assessed via analysis of variance.</p><p><strong>Results: </strong>Across all graded responses (n = 480), 364 responses (75.8%) were \"at least good\" (GCS ≥ 4). Proportions of responses that were \"at least good\" (<i>P</i> < .0001) or \"excellent\" (GCS = 5) (<i>P</i> < .0001) differed by prompt; \"at least moderate\" (GCS ≥ 3) responses did not (<i>P</i> = .687). Eighth-grade level (14.06 ± 2.3) and patient-friendly (14.33 ± 2.0) responses were significantly lower mean grade level than no prompting (<i>P</i> < .0001).</p><p><strong>Conclusion: </strong>ChatGPT provides appropriate answers to most questions on COVID-19 OD regardless of prompting. However, prompting influences response quality and grade level. ChatGPT responds at grade levels above accepted recommendations for presenting medical information to patients. Currently, ChatGPT offers significant potential for patient education as an adjunct to the conventional patient-physician relationship.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e70011"},"PeriodicalIF":1.8,"publicationDate":"2024-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11403001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142292852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Human Papillomavirus Vaccination Rates Within a Tertiary Military Medical Center.","authors":"Candace A Flagg, Benjamin K Walters, Sarah N Bowe","doi":"10.1002/oto2.149","DOIUrl":"10.1002/oto2.149","url":null,"abstract":"<p><strong>Objective: </strong>To determine our center's human papillomavirus (HPV) vaccination rate and identify common negative perceptions surrounding the vaccine to guide more effective HPV vaccine counseling.</p><p><strong>Methods: </strong>We reviewed immunization records for patients ages 11 to 26 that receive care at Brooke Army Medical Center. Vaccine uptake rate was determined by dividing the number of patients who had completed the HPV vaccine series by the total target population. From October 2021 to December 2022, a clinic survey was distributed to parents (for patients ages 11-17) or patients themselves (ages 18-26) during otolaryngology visits to poll vaccination status and attitudes toward the vaccine.</p><p><strong>Results: </strong>A total of 3038 patients ages 11 to 26 are enrolled for primary care at Brooke Army Medical Center, but only 962 (32%) are vaccine complete. Thirty-five surveys were collected during the study period. Twenty-two surveys (63%) from patients/parents reported they/their child had received the HPV vaccine. Concerns about vaccine safety, sexual behaviors, lack of immunization requirement for school, and difficulty getting scheduled were the most common reasons patients were unvaccinated.</p><p><strong>Discussion: </strong>Counseling patients on the HPV vaccine can be difficult given the common misconceptions surrounding vaccination, but understanding these attitudes will allow otolaryngologists to educate patients more effectively. This matters since patients more knowledgeable about HPV are more likely to receive the vaccine.</p><p><strong>Implications for practice: </strong>Our clinic has developed new strategies in partnership with primary care departments to facilitate more streamlined vaccination for eligible patients, and moving forward we plan to trend HPV vaccination rates over time to determine our impact on uptake.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e149"},"PeriodicalIF":1.8,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11369486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Vocal Fold Motion Impairment Associated With Diffuse Idiopathic Skeletal Hyperostosis.","authors":"Diego E Razura, Elizabeth A Shuman, Michael M Johns, Karla O'Dell","doi":"10.1002/oto2.70003","DOIUrl":"10.1002/oto2.70003","url":null,"abstract":"<p><strong>Objective: </strong>To describe the clinical courses and interventions of symptomatic patients with bilateral vocal fold motion impairment (BVFMI) attributed to diffuse idiopathic skeletal hyperostosis (DISH).</p><p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Single Institution Academic Health Center.</p><p><strong>Methods: </strong>Retrospective chart review of patients ≥18 years old evaluated and treated for symptomatic BVFMI secondary to DISH between February 2021 and March 2023. A literature review was conducted.</p><p><strong>Results: </strong>A total of 4 cases were identified. All patients were male and had symptomatic BVFMI attributed to cervical spine DISH, as seen on imaging. Symptoms ranged from life-threatening dyspnea to breathy dysphonia in addition to dysphagia. Each patient was offered surgery for DISH. Two patients underwent osteophyte removal at the C5-C6 level with improved vocal fold (VF) mobility, breathing, and voice quality. Two patients elected serial observation as voice, swallow, and airway symptoms were manageable. The literature review showed a male-dominant (100%) presentation with an average of 70 years of age. Hypertension (45%) and diabetes mellitus (36%) were the most common comorbidities. Most patients were treated surgically (55%).</p><p><strong>Conclusion: </strong>Both surgical and conservative interventions may be considered for symptomatic relief and improvement in VF mobility on a patient-to-patient basis. Further study is warranted to investigate the etiology and treatment outcomes in these cases.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e70003"},"PeriodicalIF":1.8,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11362610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142110451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The State of Craniomaxillofacial Trauma Care in Low- and Middle-Income Countries: A Scoping Review.","authors":"Zachary Elwell, Estephania Candelo, Tarika Srinivasan, Sarah Nuss, Nader Zalaquett, Gratien Tuyishimire, Isaie Ncogoza, Patrick Marc Jean-Gilles, Jacob Ndas Legbo, Travis Tollefson, David Shaye","doi":"10.1002/oto2.70000","DOIUrl":"10.1002/oto2.70000","url":null,"abstract":"<p><strong>Objective: </strong>This scoping review aims to contribute a descriptive analysis of the craniomaxillofacial trauma (CMF trauma) literature in low- and middle-income countries (LMICs) to identify knowledge gaps, direct future research, and inform policy.</p><p><strong>Data sources: </strong>PubMed/MEDLINE, Cochrane Review, EMBASE, ClinicalTrials.gov, and Google Scholar from January 1, 2012 to December 10, 2023.</p><p><strong>Review methods: </strong>The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) guided reporting, and the PRISMA flowchart documented database searches. Specific, predefined search terms and inclusion criteria were used for screening, and the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist was used for quality assessment. The search yielded 54 articles, with 13 meeting the inclusion criteria. Key findings were summarized and divided into 7 categories.</p><p><strong>Results: </strong>There were 10,420 patients (7739 [74.3%] male, 2681 [25.7%] female) with a male-to-female ratio of 2.9:1. The mean peak age of incidence of CMF trauma was 30.8 years, ranging from 20 to 40 years. Road traffic accidents were the leading cause (60.4%), followed by assault (27.2%) and falls (12.2%). The most common injuries were soft tissue injury (31.7%), isolated mandibular fracture (22.8%), and isolated middle-third of mandible fracture (18.1%). The most common treatments were closed reduction and immobilization (29.5%), conservative management (27.6%), and open reduction and internal fixation (19.6%). Most patients (77.8%) experienced a treatment delay due to a lack of fixation materials (54.8%) or surgeon unavailability (35.7%).</p><p><strong>Conclusion: </strong>CMF trauma remains a significant cause of global morbidity, yet there remains a lack of high-quality, CMF trauma-specific data in LMICs. Country-specific investigations are required to enhance knowledge and inform novel interventions. Implementing policy change must be community-specific and account for unique cultural barriers, attitudes, and behaviors to maximize patient care outcomes.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e70000"},"PeriodicalIF":1.8,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11358761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142110453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skull Base Osteomyelitis: A 5-Year Review and Prognostic Outcome in a Single Tertiary Institution.","authors":"Liew Yew Toong, Sakina Ghauth, Ng Yin Xuan","doi":"10.1002/oto2.70001","DOIUrl":"https://doi.org/10.1002/oto2.70001","url":null,"abstract":"<p><strong>Objective: </strong>The primary objective of this study is to review the clinical parameters associated with skull base osteomyelitis (SBO), with a secondary aim of studying their association with patient outcomes 1 and 6 months after treatment initiation.</p><p><strong>Study design: </strong>This is a single-center restrospective observational study.</p><p><strong>Setting: </strong>The study was conducted from January 2018 to December 2022 at the University Malaya Medical Center in Kuala Lumpur.</p><p><strong>Methods: </strong>Patients aged over 15 years with a diagnosis of SBO were included in the study. Clinical parameters, investigations, and follow-up records were recorded. The disease outcomes were analyzed at 1 and 6 months after treatment initiation using multivariable analyses.</p><p><strong>Results: </strong>The study identified 31 patients with SBO, the majority of whom were elderly males with comorbidities such as diabetes and hypertension. Otalgia and otorrhea were the most common symptoms, and computed tomography scans were used for diagnosis. <i>Pseudomonas aeruginosa</i> was the most commonly identified pathogen, and intravenous broad-spectrum antimicrobials were used to treat all patients. Surgical intervention was required for 25% of patients, and underlying ischemic heart disease, anemia, and single nerve palsy were significantly associated with an unfavorable prognosis. Patients with higher body mass index and elevated C-reactive protein showed poorer outcomes after 1 and 6 months of treatment, respectively.</p><p><strong>Conclusion: </strong>Early recognition, prompt treatment, better control of comorbidities, nutrition, and monitoring can improve SBO outcomes and reduce complications. Therefore, as the prevalence of SBO increases, diagnostic criteria or management guidelines should be established to guide the best clinical practice.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e70001"},"PeriodicalIF":1.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11351174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142110452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Augmented Reality-Guided Frozen Section Analysis: Bringing the Pathologist From the Laboratory to the Operating Room.","authors":"Marina Aweeda, Liyu Huang, Alexander N Perez, Kim A Ely, Mitra Mehrad, James S Lewis, Michael C Topf","doi":"10.1002/oto2.70002","DOIUrl":"https://doi.org/10.1002/oto2.70002","url":null,"abstract":"<p><p>Due to the anatomic complexity of the head and neck and variable proximity between laboratory and operating room (OR), effective communication during frozen section analysis (FSA) between surgeons and pathologists is challenging. This proof-of-concept study investigates an augmented reality (AR) protocol that allows pathologists to virtually join the OR from the laboratory. Head and neck cancer specimens were scanned ex vivo using a 3-dimensional scanner and uploaded into an AR platform. Eight head and neck specimens were discussed by surgeons and pathologists in an AR environment. AR-guided intraoperative consultation was used for specimen orientation and discussion of FSA margin sampling sites. One patient had positive initial margins on FSA and was re-resected to negative final margins. AR-guided FSA is possible and allows pathologists to join the operating from any location for intraoperative discussion.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e70002"},"PeriodicalIF":1.8,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11351170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142116973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Minor Salivary Glands as Indicators of Depth of Resection for Superficial Hypopharyngeal Carcinoma.","authors":"Tomofumi Sakagami, Yuri Noda, Naohiro Nakamura, Kensuke Suzuki, Takuo Fujisawa, Masao Yagi, Hiroto Kawasaki, Hiromasa Egawa, Wataru Sumita, Koji Tsuta, Hiroshi Iwai","doi":"10.1002/oto2.182","DOIUrl":"10.1002/oto2.182","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the utility of minor salivary glands in the hypopharynx as novel indicators for safe resection of superficial hypopharyngeal carcinomas with fewer complications.</p><p><strong>Study design: </strong>Cadaveric study.</p><p><strong>Setting: </strong>Cadavers were stored in the pathology laboratory at Kansai Medical University.</p><p><strong>Methods: </strong>Twenty-three cadaveric specimens were examined for minor salivary glands in the pyriform sinus, posterior wall, and postcricoid regions of the hypopharynx. Their count, size, and depth were assessed. Resected specimens from 5 consecutive patients with superficial hypopharyngeal carcinomas were pathologically analyzed to determine the positional relationship between cancer and minor salivary glands.</p><p><strong>Results: </strong>Minor salivary glands were present in more than 70% of patients in each region during autopsy, with the postcricoid region having a larger count and size. The glands were universally present, regardless of sex, height, or body mass index. Minor salivary glands in the pyriform sinus and postcricoid region were present at a depth of 30% from the bottom of the submucosal layer, whereas those in the posterior wall were present in the shallow muscularis. During surgery, endoscopic findings revealed minor salivary glands as small white nodules in the submucosal layer. Pathological examination of the resected specimen confirmed that the white nodule was a minor salivary gland. In addition, tumor position in relation to minor salivary glands provided an adequate margin for resection.</p><p><strong>Conclusion: </strong>Minor salivary glands may serve as reliable indicators for determining adequate deep safety margins during surgery for superficial hypopharyngeal carcinoma.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e182"},"PeriodicalIF":1.8,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11330580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vertical Partial Laryngectomy With Temporoparietal Free-Flap Reconstruction for Recurrent Laryngeal Cancer: Long-Term Study.","authors":"Sharon Tzelnick, John R de Almeida, Ralph Gilbert, David Goldstein","doi":"10.1002/oto2.179","DOIUrl":"10.1002/oto2.179","url":null,"abstract":"<p><strong>Objective: </strong>Treatment options for recurrent early glottic carcinoma's include conservative and radical surgical options. These options offer similar survival benefits with different impacts of patient's quality of life. We previously present our experience with vertical partial laryngectomy (VPL) and showed high locoregional control rates with high-quality voice results and normal swallowing.</p><p><strong>Study design: </strong>A long-term retrospective review.</p><p><strong>Setting: </strong>Tertiary Care Center.</p><p><strong>Methods: </strong>We analyzed all patients underwent VPL between the years 1995 to 2018. Long-term oncologic and functional outcomes were collected.</p><p><strong>Results: </strong>A total of 40 patients were included. The majority of whom were male (n = 38, 95%) with a mean age of 64.9 years (SD ± 9.5). With a median follow up time of 12 years (range 0-24), 9 patients (22.5%) had disease recurrence; the majority of whom (8 patients), had local recurrence and all were salvaged with total laryngectomy. Eight patients (20%) developed second primaries in the head and neck region with a median time to diagnosis of 77 months (range 8-227 months). Ten-years overall survival, disease specific survival, and local disease-free survival were 80%, 90%, and 80%, respectively. Five patients had postoperative laryngeal dysfunction with a total 10-years laryngectomy free survival of 70%.</p><p><strong>Conclusion: </strong>VPL has a sustainable oncologic outcome with a high long-term laryngectomy free survival rate. This entity is an acceptable conservative salvage option for selected postradiated recurrent laryngeal squamous cell carcinoma patients.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e179"},"PeriodicalIF":1.8,"publicationDate":"2024-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11330586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Idiopathic Subglottic Stenosis in Non-Caucasian Women.","authors":"Amber Suk, Salem Dehom, Nihal Punjabi, VyVy N Young, Priya D Krishna, Lindsay Reder, Karla O'Dell, Grant E Gochman, Ethan Simmons, Sunil P Verma, Matthew Harmon, Philip A Weissbrod, Jin Yang, Shanalee Tamares, Brianna K Crawley","doi":"10.1002/oto2.180","DOIUrl":"10.1002/oto2.180","url":null,"abstract":"<p><strong>Objective: </strong>To characterize presentation, disease course, and treatment of idiopathic subglottic stenosis (iSGS) in non-Caucasian women and compare this cohort to the predominantly female, Caucasian patient cohorts identified in the literature.</p><p><strong>Study design: </strong>Retrospective review. Results are compared to systematic review of demographics.</p><p><strong>Setting: </strong>Multiple California institutions from 2008 to 2021.</p><p><strong>Methods: </strong>Patients with intubation within 2 years of disease or who met exclusion criteria listed in prior publications were excluded. A systematic review of iSGS patient demographics was also completed for comparison.</p><p><strong>Results: </strong>Of 421 patients with iSGS, 58 self-identified as non-Caucasian women, with 50 ultimately included. Mean age of onset was 45.1 years old (95% confidence interval [CI], 41.5-48.8), and mean age at diagnosis was 47.2 years (95% CI, 43.6-50.7). Mean Charlson comorbidity index was 1.06 (n = 49, 95% CI, 0.69-1.44). At diagnosis, Cotton-Meyer severity scores (documented in n = 45) were Cotton-Myer (CM) I (28.9%), CM II (40%), and CM III (31.1%). Mean age at first endoscopic surgery was 47.7 (95% CI, 44.2-51.3) years. 64% experienced disease recurrence with a median of 11 months between their first and second surgery. Our systematic review identified 60 studies that reported demographic features in patients with iSGS. 95% of pooled patients were Caucasian, while other demographic features were similar to the current cohort.</p><p><strong>Conclusion: </strong>The non-Caucasian population, almost 14% of this Californian cohort, does not differ from the majority Caucasian population detailed in contemporary literature. This cohort supports the presence of some racial and ethnic heterogeneity in this disease population.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e180"},"PeriodicalIF":1.8,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11327399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}