OTO Open最新文献

{"title":"Prevalence and Risk Factors for Swallowing Dysfunction in Patients With Laryngomalacia Treated Medically and Surgically.","authors":"Janelle Sloychuk, Amy Callaghan, Amanda Adsett, Daniela M Isaac, Hamdy El-Hakim, Andre Isaac","doi":"10.1002/oto2.70025","DOIUrl":"10.1002/oto2.70025","url":null,"abstract":"<p><strong>Objective: </strong>To identify the prevalence, pattern, and nature of swallowing dysfunction (SwD) in a consecutive cohort of patients with laryngomalacia (LM), and to determine factors associated with a higher burden of SwD.</p><p><strong>Study design: </strong>This was a retrospective review of consecutive patients diagnosed with LM by 2 pediatric otolaryngologists between 2013 and 2022 and a minimum of 3-month follow-up.</p><p><strong>Setting: </strong>Tertiary care pediatric otolaryngology referral center.</p><p><strong>Methods: </strong>Consecutive cohort of patients less than 3 years old with LM diagnosed on flexible laryngoscopy were reviewed. Patients with incomplete follow-up, lack of swallowing assessment, and genetic conditions or syndromes were excluded. All patients underwent at minimum a systematic clinical swallowing evaluation by a speech-language pathologist specialized in pediatric dysphagia. Patients with concerning clinical exams underwent instrumental swallow evaluation (Videofluoroscopic Swallow Study [VFSS] or Flexible Endoscopic Evaluation of Swallowing [FEES]). The prevalence of abnormalities of clinical swallowing evaluation, instrumental swallow evaluation data, and details of management were collected.</p><p><strong>Results: </strong>Two hundred and twelve patients met criteria and were included in the final analysis. One hundred and fifteen patients (54%) had an instrumental assessment (VFSS or FEES). Of the instrumental assessments performed, 96 (69%) were abnormal. Of the total patient cohort, 55 (26%) had laryngeal penetration and/or aspiration. One hundred and seventeen (55%) had clinical or instrumental indications for intervention, with 18 (8%) requiring tube feeding. Patients with severe LM and those treated surgically had a statistically significant higher rate of penetration and aspiration.</p><p><strong>Conclusion: </strong>Patients with LM have a high burden of dysphagia requiring medical intervention. The authors advocate for routine and systematic assessment of all patients with LM for swallowing dysfunction.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 4","pages":"e70025"},"PeriodicalIF":1.8,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11442851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redundancy of Pharmacologic Ingredients in Over-the-Counter Nasal Sprays.","authors":"Lily N Trinh, Diandra K Smith, Edward D McCoul","doi":"10.1002/oto2.70022","DOIUrl":"10.1002/oto2.70022","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate and determine the prevalence of ingredients in over-the-counter (OTC) nasal sprays.</p><p><strong>Study design: </strong>Cross-sectional.</p><p><strong>Setting: </strong>Retail pharmacies.</p><p><strong>Methods: </strong>An inventory of brand-name and generic OTC nasal sprays was recorded at five national pharmacy outlets in August 2023. Data regarding the active ingredients were collected on commercial websites, MedlinePlus and drugs.com, and frequency statistics were calculated.</p><p><strong>Results: </strong>Five pharmacies were visited, at which 12 different brand names of nasal sprays were identified at multiple pharmacies. Nine brand names were associated with multiple formulations, accounting for 49 different products. The active ingredients included in our analysis were oxymetazoline, phenylephrine, fluticasone, triamcinolone, budesonide, azelastine, cromolyn sodium, and mometasone. Nasal decongestants had the greatest number of brand name formulations compared to intranasal steroids and antihistamine sprays which had limited choices. Products that included oxymetazoline were the most widely marketed drug (51 unique products) followed sodium chloride (40 unique products).</p><p><strong>Conclusion: </strong>These findings suggest that there are widespread redundancies in the OTC nasal spray market. Clinician should be aware of the redundancy in OTC formulations and encourage patients to read the labels in order to make informed decisions regarding their use of OTC medications.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 4","pages":"e70022"},"PeriodicalIF":1.8,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11442747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Social Media on Otolaryngology Literature: Analyzing the Correlation Between Altmetrics and Citation Count.","authors":"Salman Hussain, Abdullah Almansouri, Hamad Almhanedi","doi":"10.1002/oto2.70010","DOIUrl":"10.1002/oto2.70010","url":null,"abstract":"<p><strong>Objective: </strong>The altmetric attention score (AAS) is an alternative metric that tracks article sharing via online platforms, reflecting an article's online attention trend. The objective of this study was to analyze the impact of social media on Otolaryngology-Head and Neck Surgery (OHNS) literature and analyze the correlation between AAS and citation count.</p><p><strong>Study design and setting: </strong>A retrospective review of otolaryngology journal article citation data and Altmetric attention score.</p><p><strong>Methods: </strong>The top 10 OHNS journals with highest impact factors were identified using the Journal Citation Reports (JCR). The number of citations in 2018 and 2019 were extracted from JCR and AAS was extracted from the altmetrics website. The primary outcome of this study was to establish whether a correlation between AAS and citation count exists, and whether AAS could serve as a valid alternative metric to assess the quality of individual articles.</p><p><strong>Results: </strong>By analyzing data from 3729 articles, a weak statistically significant positive correlation was identified between AAS and citation count (<i>r</i> = 0.18, <i>P</i> < .001), and between number of citations and Twitter activity (<i>r</i> = 0.18, <i>P</i> < .001). In addition, a statistically significant strong correlation was seen between Twitter activity and AAS (<i>r</i> = 0.79, <i>P</i> < .001).</p><p><strong>Conclusion: </strong>The current results clearly illustrate a weak correlation between AAS and citations and between Twitter activity and citations. Due to various limitations, the use of AAS should be limited to serve as a complementary metric to the current gold standard rather than an alternative metric.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 4","pages":"e70010"},"PeriodicalIF":1.8,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Rectal Versus Oral Chloral Hydrate in Pediatric Auditory Brainstem Response: Randomized Controlled Trial.","authors":"Chutaporn Siripermpool, Nalinee Pattrakornkul, Thanitda Thongsattra, Narit Jianbunjongkit","doi":"10.1002/oto2.70023","DOIUrl":"10.1002/oto2.70023","url":null,"abstract":"<p><strong>Objective: </strong>To compare sedation success rates between rectal (RCH) and oral chloral hydrate (OCH) administration in children undergoing auditory brainstem response (ABR) testing and assess the incidence of adverse effects.</p><p><strong>Study design: </strong>Randomized controlled trial, performed between May 2023 and August 2023.</p><p><strong>Setting: </strong>Ear, Nose, and Throat Outpatient Department at tertiary care hospital.</p><p><strong>Methods: </strong>Pediatric patients aged 1 to 5 years, who were indicated for ABR testing were enrolled and randomly divided into 2 groups. The control group received 10% wt/vol chloral hydrate orally at a dose of 50 mg/kg, while the other group received the same dose through rectal administration. Onset of sedation, duration of sedation, recovery time, vital signs, and adverse effects were recorded and analyzed to assess sedative effectiveness and safety.</p><p><strong>Results: </strong>Eighty-eight children were randomly assigned to RCH or OCH administration groups, the sedation success rates of RCH and OCH groups were 84.09% and 90.91%, respectively (<i>P</i> = .33). Adverse effects were detected in 11 children (12.5%), with a vomiting rate of 20.45% in the oral group versus 0% in the rectal group (<i>P</i> = .002). The diarrhea rate was 4.55% in the rectal group versus 0% in the oral group (<i>P</i> = .16). In either group, no serious adverse effects were documented.</p><p><strong>Conclusion: </strong>RCH and OCH are both safe and effective for short-term sedation in pediatric patients during ABR testing. Interestingly, RCH administration offers a high success rate without vomiting or major adverse effects. This study established the effectiveness of RCH for sedation in children under specialized supervision.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 4","pages":"e70023"},"PeriodicalIF":1.8,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supraglottic Lymphatic Malformation Managed With Transoral Microelectrode Surgery (TOMES).","authors":"Rosa Hernández, Altea Esteve, Carmen Fernández, Enrique Zapater","doi":"10.1002/oto2.70020","DOIUrl":"10.1002/oto2.70020","url":null,"abstract":"","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 4","pages":"e70020"},"PeriodicalIF":1.8,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11439146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of an Automated Triage System for Longstanding Dizzy Patients Using Artificial Intelligence.","authors":"Santiago Romero-Brufau, Robert J Macielak, Jeffrey P Staab, Scott D Z Eggers, Colin L W Driscoll, Neil T Shepard, Douglas J Totten, Sabrina M Albertson, Kalyan S Pasupathy, Devin L McCaslin","doi":"10.1002/oto2.70006","DOIUrl":"https://doi.org/10.1002/oto2.70006","url":null,"abstract":"<p><strong>Objective: </strong>To report the first steps of a project to automate and optimize scheduling of multidisciplinary consultations for patients with longstanding dizziness utilizing artificial intelligence.</p><p><strong>Study design: </strong>Retrospective case review.</p><p><strong>Setting: </strong>Quaternary referral center.</p><p><strong>Methods: </strong>A previsit self-report questionnaire was developed to query patients about their complaints of longstanding dizziness. We convened an expert panel of clinicians to review diagnostic outcomes for 98 patients and used a consensus approach to retrospectively determine what would have been the ideal appointments based on the patient's final diagnoses. These results were then compared retrospectively to the actual patient schedules. From these data, a machine learning algorithm was trained and validated to automate the triage process.</p><p><strong>Results: </strong>Compared with the ideal itineraries determined retrospectively with our expert panel, visits scheduled by the triage clinicians showed a mean concordance of 70%, and our machine learning algorithm triage showed a mean concordance of 79%.</p><p><strong>Conclusion: </strong>Manual triage by clinicians for dizzy patients is a time-consuming and costly process. The formulated first-generation automated triage algorithm achieved similar results to clinicians when triaging dizzy patients using data obtained directly from an online previsit questionnaire.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e70006"},"PeriodicalIF":1.8,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11427795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ChatGPT Generated Otorhinolaryngology Multiple-Choice Questions: Quality, Psychometric Properties, and Suitability for Assessments.","authors":"Cecilia Lotto, Sean C Sheppard, Wilma Anschuetz, Daniel Stricker, Giulia Molinari, Sören Huwendiek, Lukas Anschuetz","doi":"10.1002/oto2.70018","DOIUrl":"https://doi.org/10.1002/oto2.70018","url":null,"abstract":"<p><strong>Objective: </strong>To explore Chat Generative Pretrained Transformer's (ChatGPT's) capability to create multiple-choice questions about otorhinolaryngology (ORL).</p><p><strong>Study design: </strong>Experimental question generation and exam simulation.</p><p><strong>Setting: </strong>Tertiary academic center.</p><p><strong>Methods: </strong>ChatGPT 3.5 was prompted: \"Can you please create a challenging 20-question multiple-choice questionnaire about clinical cases in otolaryngology, offering five answer options?.\" The generated questionnaire was sent to medical students, residents, and consultants. Questions were investigated regarding quality criteria. Answers were anonymized and the resulting data was analyzed in terms of difficulty and internal consistency.</p><p><strong>Results: </strong>ChatGPT 3.5 generated 20 exam questions of which 1 question was considered off-topic, 3 questions had a false answer, and 3 questions had multiple correct answers. Subspecialty theme repartition was as follows: 5 questions were on otology, 5 about rhinology, and 10 questions addressed head and neck. The qualities of focus and relevance were good while the vignette and distractor qualities were low. The level of difficulty was suitable for undergraduate medical students (n = 24), but too easy for residents (n = 30) or consultants (n = 10) in ORL. Cronbach's <i>α</i> was highest (.69) with 15 selected questions using students' results.</p><p><strong>Conclusion: </strong>ChatGPT 3.5 is able to generate grammatically correct simple ORL multiple choice questions for a medical student level. However, the overall quality of the questions was average, needing thorough review and revision by a medical expert to ensure suitability in future exams.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e70018"},"PeriodicalIF":1.8,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11424880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Endoscopic Anterior Cricoid Rib Grafting: A Feasibility Study in An Animal Model.","authors":"Bshair Aldriweesh, Nasser Almutairi, Waleed Alshareef, Abdullah Sindi, Ahmed Alammar","doi":"10.1002/oto2.70012","DOIUrl":"10.1002/oto2.70012","url":null,"abstract":"<p><strong>Objective: </strong>The objective of our study was to document the feasibility of a novel endoscopic anterior cricoid split and rib grafting technique in a goat airway model.</p><p><strong>Study design: </strong>Feasibility pilot animal study.</p><p><strong>Setting: </strong>Animal surgical laboratory at a tertiary hospital and research center.</p><p><strong>Methods: </strong>Three Ardhi goats were utilized. After harvesting and shaping the rib graft, 2 sutures were inserted transversely into the graft. An endoscopic midline anterior cricoid split was performed and extended down through the first tracheal ring, followed by a balloon dilation of the site. Next, the 2 lower and upper graft suture ends were sequentially passed as endo-extra laryngeal sutures and tied on the anterior neck skin. Laryngeal stent was utilized in 1 goat following graft placement.</p><p><strong>Results: </strong>The surgery was successful in all included animals and bronchoscopy performed 7 days after surgery, revealed that the anterior graft was in good position. One goat developed surgical site infection leading to partial graft resorption.</p><p><strong>Conclusion: </strong>This study demonstrated the feasibility of this novel procedure which is potentially useful for patients who are candidates for a single-stage reconstruction. Future studies should investigate the safety and validity of this technique in a model with subglottic stenosis.</p><p><strong>Level of evidence: </strong>NA.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e70012"},"PeriodicalIF":1.8,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11418163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Educational Gaps in Dermatologic Diagnoses Among Otolaryngology Residents.","authors":"Sasan Darain Noveir, Wasiq Nadeem, Carol E Cheng, Matthew K Lee","doi":"10.1002/oto2.70017","DOIUrl":"https://doi.org/10.1002/oto2.70017","url":null,"abstract":"<p><p>Otolaryngologists frequently serve as the first touchpoint for patients presenting with dermatologic conditions of the head and neck. This study aims to identify and quantify gaps in dermatologic training among otolaryngology residents, and to assess their diagnostic accuracy in comparison to dermatology residents. It comprised 14 multiple-choice questions focused on common dermatologic diagnoses related to the head and neck. Sixty-one dermatology and 36 otolaryngology residents participated in the study. Dermatology residents significantly outperformed otolaryngology residents, with average scores of 90% (SD = 8) compared to 71% (SD = 10) (<i>P</i> < .001). The observed effect size (Cohen's <i>d</i> = 2.010) significantly exceeded the expected effect size (0.603). Otolaryngology residents performed significantly lower on 7 out of the 14 questions. Analysis based on postgraduate year level showed no significant differences in scores within dermatology (<i>P</i> = .119) or otolaryngology (<i>P</i> = .402) residency programs.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e70017"},"PeriodicalIF":1.8,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11420511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-World Evaluation of Asthma Severity Following Endoscopic Sinus Surgery in Chronic Rhinosinusitis Patients.","authors":"Anyull D B Caballero, Estephania Candelo, Karol Avila-Castano, Alaa Alhalabi, Angela M Donaldson","doi":"10.1002/oto2.70013","DOIUrl":"https://doi.org/10.1002/oto2.70013","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the impact of endoscopic sinus surgery (ESS) on asthma severity up to 12 months after surgical intervention.</p><p><strong>Study design: </strong>Retrospective cohort.</p><p><strong>Setting: </strong>Tertiary care center.</p><p><strong>Methods: </strong>Patients with a history of asthma and Chronic Rhinosinusitis (CRS) who underwent ESS between 2013 and 2023 were included. Asthma severity was assessed according to current Global Initiative for Asthma (GINA) guidelines, classifying patients into mild, moderate, and severe based on medication requirements. Asthma severity was evaluated up to 3 months prior to ESS and 1-year post-ESS. Patients with aspirin-exacerbated respiratory disease (AERD) were excluded. Statistical analysis was performed using McNemar test and Wilcoxon signed-rank test to assess differences in asthma severity, medication doses, and number of medications.</p><p><strong>Results: </strong>Sixty-five patients were included, of which 44 (67.7%) had CRS with nasal polyps (CRSwNP) and 21 (32.3%) had CRS without nasal polyps (CRSsNP). No significant differences were found in asthma severity pre- and post-ESS (<i>P</i> = .175). Similarly, no differences were found in ICS doses (<i>P</i> = .999), total number of prescribed medications (<i>P</i> = .157) or presence of exacerbations before and after ESS (<i>P</i> = .078). However, a significant increase in time from last rescue inhaler use was noted after ESS, increasing from a median of 6.71 to 23.1 weeks (<i>P</i> = .004).</p><p><strong>Conclusion: </strong>This study is the first to assess the impact of ESS on asthma severity in a real-world setting. Our findings suggest that ESS does not impact asthma severity classification. However, it might provide relief of asthma symptoms in the early postoperative period.</p>","PeriodicalId":19697,"journal":{"name":"OTO Open","volume":"8 3","pages":"e70013"},"PeriodicalIF":1.8,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11409052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142292853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}