{"title":"Is Interest in Surgical Retina Fellowship Waning and How Can We Create Change?","authors":"Avni P Finn, Jayanth Sridhar","doi":"10.3928/23258160-20260510-01","DOIUrl":"https://doi.org/10.3928/23258160-20260510-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":"57 6","pages":"343-344"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148218622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tsai-Chu Yeh, Jonathan B Lin, Prithvi Mruthyunjaya, Theodore Leng, Charles DeBoer, Yasir J Sepah, David R P Almeida, Stephen Smith, Vinit B Mahajan
{"title":"A Simplified Classification for Age-Related Macular Degeneration Based on Optical Coherence Tomography.","authors":"Tsai-Chu Yeh, Jonathan B Lin, Prithvi Mruthyunjaya, Theodore Leng, Charles DeBoer, Yasir J Sepah, David R P Almeida, Stephen Smith, Vinit B Mahajan","doi":"10.3928/23258160-20260409-02","DOIUrl":"10.3928/23258160-20260409-02","url":null,"abstract":"<p><strong>Background and objective: </strong>As optical coherence tomography (OCT) has enabled the identification of an expanding set of age-related macular degeneration (AMD) risk biomarkers and become central to routine clinical practice, there remains a need for a simplified grading scheme that allows physicians to communicate and synchronize AMD grading directly from standard OCT imaging rather than relying on traditional color fundus imaging. This study aims to establish a standardized OCT-based AMD classification that balances diagnostic accuracy with practicality for use across clinical and research settings.</p><p><strong>Patients and methods: </strong>Spectral-domain OCT scans were independently graded by two retinal specialists following the newly proposed Stanford OCT-Based AMD Classification (SOAC). Discrepancies were adjudicated by a third independent retinal specialist. Inter-grader agreement was assessed using weighted kappa coefficients.</p><p><strong>Results: </strong>Among the 109 eyes from 108 patients (mean age 79.61 ± 7.57 years; 41.7% men, 58.3% women), AMD staging based on SOAC was distributed as follows: normal aging in nine patients (8.3%), early AMD in 16 (14.7%), intermediate AMD in 32 (29.4%), neovascular AMD (nAMD) in 18 (16.5%), geographic atrophy (GA) in 20 (18.3%), and combined nAMD and GA in 14 (12.8%). The overall intergrader agreement demonstrated robust consistency, with a weighted kappa value of 0.95 (95% CI: 0.92-0.98), signifying excellent intergrader reliability and reinforcing the validity of SOAC.</p><p><strong>Conclusion: </strong>SOAC provides a standardized, OCT-based framework for AMD grading that demonstrates high intergrader agreement. By enabling consistent classification from commonly acquired OCT scans, SOAC supports reliable disease staging and facilitates integration across clinical studies and translational research. As imaging and molecular data continue to expand, SOAC can serve as a common OCT-based reference for phenotype refinement and longitudinal AMD studies.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"369-375"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147982781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan B Lin, Karen M Wai, Amer F Alsoudi, Murtaza K Adam, Prithvi Mruthyunjaya, Ehsan Rahimy
{"title":"Longitudinal Trends of Intraocular Lens Dislocation in a Federated Electronic Health Record Network.","authors":"Jonathan B Lin, Karen M Wai, Amer F Alsoudi, Murtaza K Adam, Prithvi Mruthyunjaya, Ehsan Rahimy","doi":"10.3928/23258160-20260511-01","DOIUrl":"10.3928/23258160-20260511-01","url":null,"abstract":"<p><strong>Background and objective: </strong>The aim of this study was to characterize longitudinal trends in intraocular lens (IOL) dislocation in patients after cataract surgery.</p><p><strong>Patients and methods: </strong>Using the TriNetX network, a retrospective cohort study was conducted of 866,010 patients who underwent cataract surgery from the years 2000 to 2024. Those patients who had experienced IOL dislocation based on International Classification of Diseases, Ninth and Tenth Revision (ICD-9 and -10) codes were identified. Patients with risk factors for IOL dislocation, such as ocular trauma, prior intravitreal injections, prior pars plana vitrectomy, pseudoexfoliation glaucoma, and Marfan syndrome, based on ICD-9/-10 and Current Procedural Terminology (CPT) codes, were also identified.</p><p><strong>Results: </strong>From 2020 to 2024, 9,929 (1.1%) of the 866,010 patients experienced IOL dislocation. Over the past 2 decades, there was a significant monotonic increase in the incidence rate of IOL dislocation (<i>P</i> < .01), as well as ocular trauma (<i>P</i> < .01), intravitreal injections (<i>P</i> < .01), and pars plana vitrectomy (<i>P</i> < .01).</p><p><strong>Conclusion: </strong>IOL dislocation is becoming increasingly common. Practitioners must be prepared to manage these conditions.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":"57 6","pages":"376-381"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148218534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prashant D Tailor, Kenny Y Wang, Timothy T Xu, Blake H Fortes, Collin G Asheim, Robert A Churchill, Matthew R Starr
{"title":"Clinical Characteristics and Outcomes of Hemorrhagic Choroidal Detachments From 2003-2020: A Single Center Experience.","authors":"Prashant D Tailor, Kenny Y Wang, Timothy T Xu, Blake H Fortes, Collin G Asheim, Robert A Churchill, Matthew R Starr","doi":"10.3928/23258160-20260413-02","DOIUrl":"10.3928/23258160-20260413-02","url":null,"abstract":"<p><strong>Background and objective: </strong>This study aimed to characterize clinical characteristics and visual outcomes of patients with hemorrhagic choroidal detachments.</p><p><strong>Patients and methods: </strong>Single-center retrospective case series of patients with hemorrhagic choroidal detachments from January 1, 2003, to December 31, 2020 at Mayo Clinic. Patients were categorized as appositional or non-appositional based on ultra-sonography.</p><p><strong>Results: </strong>Among 39 cases with hemorrhagic choroidal detachments, 15 (38%) were appositional and 24 (62%) were non-appositional. There was a significant difference between the appositional and non-appositional groups in mean initial logMAR visual acuity (VA) (2.8 [<i>SD</i> = 0.20] vs 2.2 [<i>SD</i> = 0.78], <i>P</i> < .001). However, no difference was observed in final logMAR VA (1.9 [<i>SD</i> = 1.2] vs 1.5 [<i>SD</i> = 1.1], <i>P</i> = .30). Comparison between surgical (<i>N</i> = 9) versus non-surgical (<i>N</i> = 5) hemorrhagic appositional choroidal detachments cases revealed no differences in outcomes. Comparison between anticoagulated (<i>N</i> = 21) versus nonanticoagulated (<i>N</i> = 18) patients with hemorrhagic choroidal detachments also revealed no differences in outcomes.</p><p><strong>Conclusion: </strong>Patients with appositional and nonappositional hemorrhagic choroidal detachments did not differ significantly with regards to visual outcome. Surgical intervention was not associated with improved final vision in this cohort.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":"57 6","pages":"350-354"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148218843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sumit Sharma, Peter Y Chang, Rene Y Choi, Phoebe Lin, Eric B Suhler, Alison H Zhao, Kanika Seth, Rishi P Singh
{"title":"One-year CALM Outcomes: Data From a Real-world Registry Study of the 0.18-mg Fluocinolone Acetonide Intravitreal Implant for the Treatment of Patients With Non-infectious Uveitis Affecting the Posterior Segment.","authors":"Sumit Sharma, Peter Y Chang, Rene Y Choi, Phoebe Lin, Eric B Suhler, Alison H Zhao, Kanika Seth, Rishi P Singh","doi":"10.3928/23258160-20260409-01","DOIUrl":"10.3928/23258160-20260409-01","url":null,"abstract":"<p><strong>Background and objective: </strong>The CALM Registry was a retrospective cohort study that assessed real-world outcomes of treating chronic noninfectious uveitis affecting the posterior segment (NIU-PS) with the 0.18-mg fluocinolone acetonide implant (FAi).</p><p><strong>Patients and methods: </strong>Eligible participants were aged ≥18 years and diagnosed with chronic NIU-PS. Safety and effectiveness outcomes, as available, were collected from charts.</p><p><strong>Results: </strong>Two hundred sixty-seven eyes from 200 participants received the FAi (mean age, 62.8 years; 10.5% phakic). Median intraocular pressure remained stable at 14.0 mmHg. Two cataract surgeries were reported. In the 12 months pre-FAi, 84.1% of eyes had ≥1 recurrence of uveitis; 12 months post-implant, the recurrence rate was 12.0%, and retinal thickness reduced significantly (<i>P</i> < .05). The proportion of eyes with ≥ 20/40 visual acuity was stable from baseline (49%) to 12 months (55%).</p><p><strong>Conclusion: </strong>Real-world data from the CALM Registry study indicate effective control of chronic NIU-PS with the FAi and no new safety signals.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"362-368"},"PeriodicalIF":1.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147982799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pauline Scherm, Devi K Schwartz, Marcelo Alexandre Agra Cavalcante Costa, Homero Augusto de Miranda, Marco H Ji, Andrew A Moshfeghi, Jochen Kumm, Eric Nudleman, Emmett T Cunningham, Darius M Moshfeghi
{"title":"Universal Newborn Eye Screening in São Paulo, Brazil.","authors":"Pauline Scherm, Devi K Schwartz, Marcelo Alexandre Agra Cavalcante Costa, Homero Augusto de Miranda, Marco H Ji, Andrew A Moshfeghi, Jochen Kumm, Eric Nudleman, Emmett T Cunningham, Darius M Moshfeghi","doi":"10.3928/23258160-20260302-01","DOIUrl":"10.3928/23258160-20260302-01","url":null,"abstract":"<p><p>This brief report describes the incidence and characteristics of ocular abnormalities in healthy term newborn infants (HTNI) in 5,000 consecutive eye examinations from a database of 32,000 infants from 17 hospitals in São Paulo, Brazil. Imaging consisted of five views of the retina (optic nerve center, superior, inferior, nasal, temporal) with 130° wide-angle lens and one view of the anterior segment in each eye. These images were curated on four separate occasions for the presence or absence of ocular abnormality by a pediatric retina specialist. All images were obtained within 72 hours of birth. A total of 59,792 images were curated: Right Eye Normal (21,473 images), Left Eye Normal (21,983 images), Right Eye Abnormal (8,397 images), Left Eye Abnormal (7,939 images). An ocular abnormality appeared in 37.7% of patients; 4.88% showed a referral-warranted pathology. Based on these data, it is not unreasonable to consider instituting universal newborn eye screening in HTNI.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"334-337"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scheduling Standardization as an Upstream Safety Lever for Ophthalmic Operating Room Access.","authors":"Henry Bair","doi":"10.3928/23258160-20260128-01","DOIUrl":"https://doi.org/10.3928/23258160-20260128-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":"57 5","pages":"338"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147949269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason Xiao, Negin Yavari, Hasitha Nimmagadda, Prithvi Mruthyunjaya, Ehsan Rahimy, Stephen J Smith, Chase A Ludwig, Euna Koo, Karen M Wai
{"title":"Association Between Mental Health Disorders in Age-Related Macular Degeneration: A Cohort Study Using a Global Health Records Network.","authors":"Jason Xiao, Negin Yavari, Hasitha Nimmagadda, Prithvi Mruthyunjaya, Ehsan Rahimy, Stephen J Smith, Chase A Ludwig, Euna Koo, Karen M Wai","doi":"10.3928/23258160-20260311-02","DOIUrl":"10.3928/23258160-20260311-02","url":null,"abstract":"<p><strong>Background and objective: </strong>This study assessed risk of mental health disorders in patients with age-related macular degeneration (AMD).</p><p><strong>Patients and methods: </strong>Data were obtained from an aggregated electronic health records database. Patients who were diagnosed with AMD with cataract were propensity score-matched with cataract controls. Diagnoses were identified using International Classification of Diseases, 10th Revision (ICD-10) codes. Subgroup analyses evaluated relative risk (RR) of new diagnoses of mental health disorders among patients with dry AMD, neovascular AMD (nAMD), vision impairment, and receipt of intravitreal therapy.</p><p><strong>Results: </strong>After matching, 126,799 cases comprising 53.1% female patients with a mean age of 74.6 ± 8.9 years were included. Patients with AMD and cataract had elevated risk of receiving diagnoses of depression (RR = 1.27; 95% CI 1.24-1.29) and anxiety (RR = 1.19; 1.17-1.22). These patients were also at increased risk for self-harm (RR = 1.16), substance use (RR = 1.10), dysthymia (RR = 1.41), and psychosis (RR = 1.22) (all <i>P</i> < .05). The presence of visual impairment amplified these risks, particularly for depression (RR = 1.97) and anxiety (RR = 1.62). Patients with dry AMD had an increased risk of depression and anxiety compared to those with nAMD. Treatment with intravitreal injections in nAMD patients was associated with decreased risk of depression (RR = 0.88) and anxiety (RR = 0.82).</p><p><strong>Conclusions: </strong>AMD is associated with increased risk of mental health disorders, including anxiety, depression, and self-harm, particularly in the first year following diagnosis. Risk varies by disease subtype, visual function, and treatment status.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":"57 5","pages":"301-308"},"PeriodicalIF":1.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147949138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}