Ophthalmic surgery, lasers & imaging retina最新文献

{"title":"Trends in Research Payments for Age-related Macular Degeneration From 2015 to 2021.","authors":"April M Lee, Timothy T Xu, Matthew R Starr","doi":"10.3928/23258160-20240903-01","DOIUrl":"10.3928/23258160-20240903-01","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate characteristics of industry and public research payments for age-related macular degeneration studies.</p><p><strong>Materials and methods: </strong>Studies involving \"age-related macular degeneration\" or \"AMD\" from 2015 to 2021 were extracted from the Open Payments Database and the National Eye Institute RePORTER tool and compared to each other.</p><p><strong>Results: </strong>From 2015 to 2021, 620 ophthalmologists received $178,394,734.09 in industry research payments with a 76.9% increase from 2015 to 2020 and a subsequent 40.7% decrease in 2021. There were 84 female industry funding recipients (13.7%) compared to 528 (86.3%) male recipients (<i>P</i> < 0.001). For public funding, 119 ophthalmologists received $157,319,575.00 with a 31.0% increase from 2015 to 2021. Among 119 principal investigators, 37 (31.1%) were women and 82 (68.9%) were men (<i>P</i> = 0.05).</p><p><strong>Conclusion: </strong>Industry-funded and publicly funded age-related macular degeneration-related research payments overall increased from 2015 to 2021. Funding distribution by sex trended towards male recipients. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:95-100.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"95-100"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142292845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cross-Sectional Survey of Optometrists in Canada Regarding Referral Patterns and a Needs Assessment for an Artificial Intelligence Referral Screening Tool for Epiretinal Membrane.","authors":"Reut Shor, Marko Popovic, Andrew Mihalache, Rajeev H Muni","doi":"10.3928/23258160-20241217-01","DOIUrl":"https://doi.org/10.3928/23258160-20241217-01","url":null,"abstract":"<p><strong>Background and objective: </strong>This study evaluated optometrists' referral patterns for epiretinal membrane (ERM) patients in Ontario, Canada, and their attitudes towards an artificial intelligence (AI) tool for improving referral accuracy. An anonymous online survey with 11 questions was conducted.</p><p><strong>Patients and methods: </strong>The survey targeted optometrists across Ontario, Canada. The survey aimed to understand optometrists' reasons for referring ERM patients to retina specialists, their expectations of the specialists' management, and their openness to using an AI tool for triage. To prevent bias, the survey described an AI tool as an online consultation feature limited to predefined questions without directly mentioning \"AI.\" The main objective was to assess if this AI tool could decrease unnecessary ERM referrals to retina specialists.</p><p><strong>Results: </strong>A total of 135 optometrists participated. They reported seeing an average of eight ERM cases monthly, referring every fourth case to a specialist. The primary referral reason (84.3%) was to evaluate for surgery. In terms of referral confidence, 34.3% felt fully confident (5/5), and 47.8% slightly less so (4/5). They anticipated that 20% of patients would have a change in management post-consultation with a specialist. When introduced to the concept of an online consultation tool for patient screening, optometrists believed it could reduce their ERM referrals by 40%.</p><p><strong>Conclusions: </strong>Optometrists often refer ERM patients to retina specialists. An AI tool for screening ERM referrals, based on presenting vision and OCT images, could significantly lower the number of unnecessary referrals, offering clinical guidance to optometrists. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:XX-XX.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-4"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Giant Choroidal Cavern in a Case of Rod-Cone Dystrophy: A Rare Presentation.","authors":"Rajul Shah, Udit Ajmani, Sameera Nayak, Niroj Kumar Sahoo, P Srinivas Rao, Brijesh Takkar","doi":"10.3928/23258160-20241216-02","DOIUrl":"https://doi.org/10.3928/23258160-20241216-02","url":null,"abstract":"<p><p>This report presents a case of a 22-year-old woman with bilateral giant choroidal caverns (CCs) in rod-cone dystrophy. Her best-corrected visual acuity was 20/80 in the right eye and 20/50 in the left eye. Fundus examination showed optic nerve pallor, narrowed blood vessels, and diffuse pigmentary changes. Fundus autofluorescence showed a central area of reduced autofluorescence surrounded by stippled autofluorescence. An electroretinogram showed decreased amplitude of both scotopic and photopic waves, consistent with a diagnosis of rod-cone dystrophy (retinitis pigmentosa). Optical coherence tomography revealed large CC and foveal atrophy in each eye. A giant CC alongside rod-cone dystrophy is a distinctive feature. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:XX-XX.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-3"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual Application of Methotrexate Improves Functional and Anatomical Outcomes in Diabetic Tractional Retinal Detachment.","authors":"Abdallah Safwat, Mohamed Abdullah, Ahmed Shawkat Abdelhalim, Rabei Hassanien, Khaled Mourad, Mohamed Tarek Moustafa","doi":"10.3928/23258160-20250127-03","DOIUrl":"https://doi.org/10.3928/23258160-20250127-03","url":null,"abstract":"<p><strong>Background and objective: </strong>This study evaluated the use of a dual-delivery methotrexate (MTX) strategy for diabetic tractional retinal detachment (TRD). Diabetic retinopathy (DR) is a leading cause of blindness. Inflammation plays a key role in TRD, and MTX has anti-inflammatory properties.</p><p><strong>Patients and methods: </strong>This is a pilot study that included 60 patients with TRD. They were block randomized to either MTX with pars plana vitrectomy (PPV) (<i>n</i> = 30) or PPV alone (control, <i>n</i> = 30). MTX was added to the irrigation fluid during surgery and an intra-silicone injection at the end. One month after silicone oil removal, visual acuity (VA), multifocal electroretinography (mfERG), and spectral-domain optical coherence tomography (SD-OCT) were assessed.</p><p><strong>Results: </strong>One month after silicone oil removal, VA and mfERG were significantly better with a lower prevalence of epiretinal membranes, disorganization of retinal inner layers, and cystic macular changes by SD-OCT in the MTX group.</p><p><strong>Conclusion: </strong>This study found that dual-delivery MTX during PPV is a promising strategy to improve functional and anatomical results in diabetic TRD. <b><i>[Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:XX-XX.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-8"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photodynamic Therapy for Subretinal Fluid Associated With Choroidal Nevus.","authors":"Jose Pena, Hidayet Sener, Carol L Shields","doi":"10.3928/23258160-20241216-04","DOIUrl":"https://doi.org/10.3928/23258160-20241216-04","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-2"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crocodile Skin Retinal Appearance: Miliary Distribution of Bilateral Idiopathic Multifocal Retinal Pigment Epithelial Detachments.","authors":"Alexandros Chatzirallis, Dimitrios Kalogeropoulos, Fatima Shawkat, Anna M Roszkowska, Rino Frisina, Gabriella De Salvo","doi":"10.3928/23258160-20240923-03","DOIUrl":"10.3928/23258160-20240923-03","url":null,"abstract":"<p><p>This report presents cases of an unusual appearance of bilateral idiopathic multifocal retinal pigment epithelial detachments (PEDs) in three patients, using multimodal imaging. Three patients with multiple PEDs, initially diagnosed as drusen, were referred for evaluation. They underwent comprehensive ophthalmic examination and multimodal imaging. All patients had a best-corrected visual acuity of 6/6 in both eyes. Fundoscopy revealed multiple idiopathic PEDs in a miliary distribution, resembling crocodile skin. Systemic workup excluded associated diseases, though one patient was pregnant. The pathogenesis and progression are poorly understood, but prognosis is favorable without intervention unless complications arise. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:108-112.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"108-112"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Quantitative Normative Database for Expanded Field Swept-source OCT Angiography in the Pediatric Population.","authors":"Sandra Hoyek, Francesco Romano, Mauricio Garcia, Ioanna Ploumi, Itika Garg, Jack Tracy, Katherine Millner Overbey, Cade Frederick Bennett, Matthew J Finn, Peyman Razavi, Isabella Victoria Manzano Stettler, Xinyi Ding, John B Miller, Nimesh A Patel","doi":"10.3928/23258160-20250108-03","DOIUrl":"https://doi.org/10.3928/23258160-20250108-03","url":null,"abstract":"<p><strong>Background and objective: </strong>To report quantitative vascular metrics of healthy control eyes of children, using expanded field swept-source optical coherence tomography angiography (SS-OCTA), as a baseline to compare with pathologic findings.</p><p><strong>Patients and methods: </strong>A cross-sectional observational study of healthy eyes of children (age 6 to 18) who were imaged on the PLEX Elite 9000 instrument at 100-kHz scanning rate using 3 × 3-mm, 6 × 6-mm, and 12 × 12-mm protocols centered on the fovea (2019 to 2023). Scans were uploaded to the ARI Network (Zeiss Portal v5.4) and processed with the macular density algorithm (v.0.7.3.3) to calculate vessel density (VD) and vessel skeletonized density (VSD) in the superficial capillary plexus (SCP), deep capillary plexus, and whole retina (WR) and foveal avascular zone (FAZ) metrics.</p><p><strong>Results: </strong>Forty-eight eyes of 39 children (72% male) were included. Median age was 14 years (interquartile range 10 to 16). Male sex was associated with lower VD and VSD compared to female sex (<i>P</i> < 0.05). Older age was associated with higher VD and VSD (6 × 6-mm) (<i>P</i> < 0.05) and lower FAZ circularity (<i>P</i> = 0.017). Non-Hispanic White children had a lower VD and VSD of the SCP in the inner superior ring (3 × 3-mm), a higher VD and VSD of the SCP and WR in the central ring (6 × 6-mm), and a lower FAZ area (6 × 6-mm) (<i>P</i> < 0.05).</p><p><strong>Conclusions: </strong>This study presents a database for expanded field vascular metrics in pediatric subjects across various angiogram sizes. The VD increases throughout childhood and the FAZ circularity diminishes. Future studies using SS-OCTA will need to account for influencing factors such as sex, age, race, and ethnicity. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:XX-XX.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-7"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scleral Fixation of an Intraocular Lens With Gore-Tex Suture From a Temporal Approach.","authors":"Yaqoob Qaseem, J Ben Margines, Weilin Song, Adrian Au, Omesh P Gupta, Jayanth Sridhar","doi":"10.3928/23258160-20241204-01","DOIUrl":"https://doi.org/10.3928/23258160-20241204-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-3"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary Experience With a Novel Titanium Macular Buckle in the Management of Myopic Maculopathy.","authors":"Ozgur Yalcinbayir, Sengul Ozdek, Ali Hakan Durukan, Mohsen Abou Shousha, Muhammad Samir Abd Al Shafy, Kenan Sonmez, Huseyin Egemen Kose, Ece Ozdemir-Zeydanli, Mohit Garg","doi":"10.3928/23258160-20250128-02","DOIUrl":"10.3928/23258160-20250128-02","url":null,"abstract":"<p><p>The objective of this study was to report the initial experiences of seven surgeons using a titanium macular buckle (TMB) for the treatment of myopic maculopathy. The records of 11 cases that underwent TMB placement, with or without concomitant vitrectomy, were reviewed. Collected data included demographics, type of maculopathy, pre-operative and postoperative ophthalmic findings. The intraoperative utilization of pars plana vitrectomy and any associated complications were also documented. The indications for surgery included posterior pole retinal detachment with maculoschisis, maculoschisis with an epiretinal membrane, myopic macular hole with posterior pole retinal detachment, isolated maculoschisis, and myopic macular hole. Eight of the 11 cases underwent combined titanium macular buckle placement and vitrectomy, while three patients received buckle placement without vitrectomy. Partial or complete resolution of the pathology was achieved in all cases. Best-corrected visual acuity improved in 10 out of 11 cases following surgery. A scleral perforation occurred intraoperatively in one case. The patients were followed up for a mean duration of 6.0 ± 2.3 months (range: 2 to 10 months). TMB may serve as a valuable adjunct in the surgical repair of myopic maculopathy requiring intervention. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:XX-XX.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-4"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between Janus Kinase Inhibitor Use and Development of Retinal Vein Occlusion.","authors":"Meghana Chalasani, Jonathan C Markle, Priya Shukla, Rula A Hajj-Ali, Katherine E Talcott, Rishi P Singh","doi":"10.3928/23258160-20240908-01","DOIUrl":"10.3928/23258160-20240908-01","url":null,"abstract":"<p><strong>Background and objective: </strong>Janus kinase (Jak) inhibitors may have increased risk of thromboembolism compared to tumor necrosis factor (TNF) inhibitors. This study investigates the association between Jak inhibitor use and retinal vein occlusion.</p><p><strong>Patients and methods: </strong>This retrospective, non-randomized cohort study used a federated health research network. Propensity-score matched risk ratios with 95% CI were calculated for central and branch retinal vein occlusion (CRVO, BRVO) in patients with immune-mediated inflammatory diseases (IMIDs) treated with Jak inhibitors versus TNF inhibitors.</p><p><strong>Results: </strong>Jak and TNF inhibitor cohorts each had 5,249 patients. Risk ratio for CRVO with Jak inhibitors (<i>n</i> = 11) versus TNF inhibitors (<i>n</i> = 18) was 0.61 [CI (0.29,1.29)]. Risk ratio for BRVO with Jak inhibitors (<i>n</i> = 17) compared to TNF inhibitors (<i>n</i> = 19) was 0.89 [CI (0.47,1.72)].</p><p><strong>Conclusion: </strong>This study did not find evidence of increased risk of RVO with the use of Jak inhibitors compared to TNF inhibitors among patients with IMIDs, contributing to literature on Jak inhibitor safety. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:72-78.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"72-78"},"PeriodicalIF":0.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142292842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}