Ophthalmic surgery, lasers & imaging retina最新文献

{"title":"Anticoagulation Therapy and Influence on Retinal Vein Occlusion and Intraocular Bleeding Risk Across a Large US National Database.","authors":"Matthew W Russell, Priya Shukla, Rishi P Singh, Katherine E Talcott","doi":"10.3928/23258160-20250523-01","DOIUrl":"https://doi.org/10.3928/23258160-20250523-01","url":null,"abstract":"<p><strong>Background and objective: </strong>Management of hypercoagulable states with systemic anticoagulation is standard of care. The risk of future retinal vein occlusion (RVO) development with direct oral anticoagulation agents (DOACs) has yet to be investigated in a large United States cohort.</p><p><strong>Patients and methods: </strong>Retrospective cohort study using a large ICD-10 coded database. The database was queried for patients being managed with warfarin or DOACs. Propensity score matching was then used to create comparable groups. Risk ratios for RVO and intraocular bleed development in patients without a prior diagnosis of RVO were calculated.</p><p><strong>Results: </strong>Patients managed with warfarin were found to be at significantly increased risk of developing a new diagnosis of all RVO (risk ratio [RR]: 1.49, 1.42-1.57), vitreous hemorrhage (RR: 2.14, 1.98-2.30), retinal hemorrhage (RR: 1.84, 1.71-1.97) and choroidal hemorrhage (RR: 2.06, 1.53-2.79), compared to patients managed with DOACs.</p><p><strong>Conclusion: </strong>These findings suggest DOACs are associated with significantly reduced retinal vein occlusion and intraocular bleeding risk compared to warfarin. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:XX-XX.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-6"},"PeriodicalIF":0.9,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silicone Oil into the Suprachoroidal Space: An Illustrative Report and Literature Review.","authors":"Gabriel Castilho S Barbosa, Nathália Nishiyama Tondelli, Cleide Guimarães Machado, André Vieira Gomes","doi":"10.3928/23258160-20250522-02","DOIUrl":"https://doi.org/10.3928/23258160-20250522-02","url":null,"abstract":"<p><p>Silicone oil (SO) tamponade has been widely used in vitreoretinal surgery for complex retinal detachment cases, yet its migration into unintended intraocular spaces remains an uncommon but clinically significant complication. While sub-retinal and anterior chamber migration have been more frequently described, suprachoroidal SO migration is a rare event, with few reports in the literature. The underlying mechanisms proposed for this complication include transient hypotony, infusion cannula malposition, and structural vulnerabilities within the suprachoroidal space. This review synthesizes reported cases of suprachoroidal SO migration, detailing clinical presentations, surgical management approaches, and postoperative outcomes. Various drainage techniques have been attempted, including transscleral evacuation through posterior sclerotomies, internal drainage into the vitreous cavity via pars plana incisions, and adjunctive perfluorocarbon liquid injection to facilitate oil displacement. While some cases have been managed conservatively without surgical intervention, the long-term implications of retained SO in the suprachoroidal space remain largely unknown. Given its potential association with ciliary detachment, hypotony, and visual disturbances, careful patient monitoring is warranted. The current literature lacks comprehensive studies on the biological behavior of SO within the suprachoroidal compartment, and further investigations are necessary to assess its stability, potential toxic effects, and indications for surgical removal. This review aims to provide vitreoretinal surgeons with a systematic understanding of suprachoroidal SO migration, offering insights into pathophysiology, prevention strategies, and optimal surgical management based on current evidence. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:XX-XX.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-6"},"PeriodicalIF":0.9,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Vasoproliferative Tumor in a Patient With Coats' Disease: Multiple Therapeutic Approach in Current Era.","authors":"Leonardo Bottazzi, Gaia L'Abbate, Claudia Fossataro, Maria Cristina Savastano, Riccardo Sacconi, Stanislao Rizzo, Francesco Bandello, Giuseppe Querques","doi":"10.3928/23258160-20250522-01","DOIUrl":"https://doi.org/10.3928/23258160-20250522-01","url":null,"abstract":"<p><p>This case report describes a vasoproliferative tumor in a 16-year-old male patient with Coats' disease, treated with laser photocoagulation, cryoablation, and anti-vascular endothelial growth factor injections therapies, that developed an epiretinal membrane as a complication. The surgical treatment in association with the retinal laser treatment greatly improved visual acuity. At 8 months follow-up from surgery, visual acuity had significantly improved, and macular anatomy recovered. Vasoproliferative tumors may occur in patients with Coats' disease, and in such a clinical scenario, a multiple therapeutical approach should be considered, in order to reach the best anatomical and functional outcome for the patient. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:XX-XX.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-4"},"PeriodicalIF":0.9,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ophthalmic Outcomes and Management of Retinopathy in Patients With Sickle Cell Disease: A Comprehensive Health Registry Study and Review of Management Strategies.","authors":"Purna Nangia, Karen M Wai, Adrienne W Scott, Ehsan Rahimy, Prithvi Mruthyunjaya","doi":"10.3928/23258160-20250425-01","DOIUrl":"https://doi.org/10.3928/23258160-20250425-01","url":null,"abstract":"<p><strong>Background and objective: </strong>The purpose of this study was to report the rates of ophthalmic complications and interventions in patients diagnosed with sickle cell disease (SCD) and sickle cell retinopathy (SCR), while reviewing current management strategies within the literature.</p><p><strong>Patients and methods: </strong>This retrospective cohort study included patients ≥ 18 years of age with the diagnosis of SCD and SCR. The electronic health record system TriNetX was utilized to identify patients diagnosed with SCD and SCR. The main outcome measures included rates of ophthalmic complications and interventions.</p><p><strong>Results: </strong>We identified 1,249 patients with the diagnosis of both SCD and SCR. The mean age at diagnosis of SCR was 34.9 ± 14.8 years. The most common ocular complication was vitreous hemorrhage (VH) (19.5%) followed by cataracts (17.8%), rhegmatogenous retinal detachment (12.4%), and tractional retinal detachment (4.7%). The most common ocular intervention was retinal laser photocoagulation (13.6%).</p><p><strong>Conclusions: </strong>In a large, contemporary population-based study for SCD patients with SCR, the rates of preventable visually significant complications are high. Timely screening, diagnosis, and management strategies can help prevent these complications. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:XX-XX.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-6"},"PeriodicalIF":0.9,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary Experience With a Novel Titanium Macular Buckle in the Management of Myopic Maculopathy.","authors":"Ozgur Yalcinbayir, Sengul Ozdek, Ali Hakan Durukan, Mohsen Abou Shousha, Muhammad Samir Abd Al Shafy, Kenan Sonmez, Huseyin Egemen Kose, Ece Ozdemir-Zeydanli, Mohit Garg","doi":"10.3928/23258160-20250128-02","DOIUrl":"10.3928/23258160-20250128-02","url":null,"abstract":"<p><p>The objective of this study was to report the initial experiences of seven surgeons using a titanium macular buckle (TMB) for the treatment of myopic maculopathy. The records of 11 cases that underwent TMB placement, with or without concomitant vitrectomy, were reviewed. Collected data included demographics, type of maculopathy, pre-operative and postoperative ophthalmic findings. The intraoperative utilization of pars plana vitrectomy and any associated complications were also documented. The indications for surgery included posterior pole retinal detachment with maculoschisis, maculoschisis with an epiretinal membrane, myopic macular hole with posterior pole retinal detachment, isolated maculoschisis, and myopic macular hole. Eight of the 11 cases underwent combined titanium macular buckle placement and vitrectomy, while three patients received buckle placement without vitrectomy. Partial or complete resolution of the pathology was achieved in all cases. Best-corrected visual acuity improved in 10 out of 11 cases following surgery. A scleral perforation occurred intraoperatively in one case. The patients were followed up for a mean duration of 6.0 ± 2.3 months (range: 2 to 10 months). TMB may serve as a valuable adjunct in the surgical repair of myopic maculopathy requiring intervention. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:378-381.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"378-381"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RWC Update: Surgical Management of Lamellar Macular Hole; Tamoxifen Retinopathy; Lashed Out: An Eye Injury Story.","authors":"Ashish Sharma, Lihteh Wu, Steven Bloom, Paulo Stanga, Barbara Parolini, Taku Wakabayashi, Tamer Mahmoud, Christopher Seungkyu Lee, Mauli Shah, Alay Banker, Natasha Ferreira Santos da Cruz, Kourous A Rezaei","doi":"10.3928/23258160-20250519-01","DOIUrl":"https://doi.org/10.3928/23258160-20250519-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":"56 6","pages":"324-327"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Experience on Visual Search Patterns in Retinal Imaging Analysis.","authors":"Puranjay Gupta, Neil Sheth, Reem AlAhmadi, Xincheng Yao, Michael J Heiferman","doi":"10.3928/23258160-20250228-03","DOIUrl":"10.3928/23258160-20250228-03","url":null,"abstract":"<p><strong>Background and objective: </strong>The increasing use of retinal diagnostic imaging necessitates a standardized viewing technique. This study investigates visual search patterns among ophthalmologists at various experience levels using eye-tracking technology.</p><p><strong>Patients and methods: </strong>Participants included postgraduate year 2, 3, and 4 residents, retina fellows, and attending ophthalmologists, who analyzed fundus images while their eye movements were tracked.</p><p><strong>Results: </strong>Results indicated that attendings had shorter fixation durations (0.15 ± 0.04 seconds) and saccade lengths (0.06° ± 0.01°), indicating faster image information processing than novice physicians. Experts also analyzed a higher proportion of the image area (49.43% ± 7.34%) and possessed a global-focal search pattern, suggesting increased thoroughness.</p><p><strong>Conclusion: </strong>Experts in ophthalmology demonstrate gaze characteristics that reflect faster image processing and a more thorough analysis of diagnostic imaging. We recommend that residents be taught a standardized method for image interpretation that emulates expert analysis through a disc-macula-vessel-periphery sequence with radial sweeps. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:336-344.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"336-344"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12175140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudo-inverted Halo Nevus.","authors":"Jared T Sokol, Prithvi Mruthyunjaya","doi":"10.3928/23258160-20250109-02","DOIUrl":"10.3928/23258160-20250109-02","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"382-383"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hispanic Ethnicity and Optical Coherence Tomography-based Biomarkers as Predictive Factors of Diabetic Macular Edema Refractory to Bevacizumab.","authors":"Erin Jennings, Dinah Chen, Alexi Geevarghese, Alexis Kaiser, Sara Coulon, Yasha Modi","doi":"10.3928/23258160-20250127-02","DOIUrl":"10.3928/23258160-20250127-02","url":null,"abstract":"<p><strong>Background and objective: </strong>While anti-vascular endothelial growth factor (anti-VEGF) therapy has revolutionized treatment for diabetic macular edema, many patients still manifest refractory disease. This study evaluated rates of diabetic macular edema (DME) refractory to intravitreal bevacizumab in a diverse real-world setting, with the aim of studying demographic and optical coherence tomography (OCT)-based morphological factors associated with refractory disease.</p><p><strong>Patients and methods: </strong>This was a retrospective cohort study of patients receiving treatment. Refractory DME was defined as a gain in visual acuity of < 5 letters after three consecutive injections of bevacizumab or less than 20% reduction in central retinal thickness (CRT) after three consecutive injections of bevacizumab. OCT images from preand post-injection visits were reviewed by two independent image readers. Multivariate logistic regression analysis evaluated for statistical significance between responders and those refractory to bevacizumab, and between Hispanic and non-Hispanic groups.</p><p><strong>Results: </strong>Ninety-nine patients were included. Of the participants, 42% were Hispanic, 10% were reported as white, 11% were Asian, 11% were Black, and 26% were defined as \"not reported.\" Fifty-four (54.5%) patients were refractory to bevacizumab and 45 were responders. Between responders and refractory patients, race was statistically significant (<i>P</i> = 0.04) with more refractory subjects found to be Hispanic (28/54, 51.9%). OCT morphologic characteristics (CRT, number of hyperreflective foci, disorganization of inner retinal layers, ellipsoid zone discontinuity, and subretinal fluid) were not statistically significant between responders and refractory subjects. Multivariate logistic regression demonstrated an odds ratio of 5.7 for refractory disease for Hispanic patients (CI 1.687 to 19.445, <i>P</i> = 0.01). When comparing Hispanic to non-Hispanic patients, Hispanic patients had an average lower baseline visual acuity, lower CSTs, and higher HbA1C.</p><p><strong>Conclusion: </strong>Our study showed that Hispanic patients have a nearly 6 times relatively higher likelihood of refractory disease. There is a notable under-representation of these patients in completed clinical trials for diabetic retinopathy and DME. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:346-353.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"346-353"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optic Pit Maculopathy Managed With Observation: Serial Optical Coherence Tomography Imaging of Fluctuating Macular Fluid.","authors":"Michael Y Zhao, Lauren C Kiryakoza, Landon J Rohowetz, Harry W Flynn","doi":"10.3928/23258160-20250326-01","DOIUrl":"10.3928/23258160-20250326-01","url":null,"abstract":"<p><p>Observation with optical coherence tomography (OCT) is a reasonable management approach for optic pit maculopathy presenting with macular fluid. We describe two patients with optic pit maculopathy who exhibited preserved vision and fluctuating macular fluid managed with serial OCTs. A 49-year-old woman presented with blurred vision in the left eye. Best-corrected visual acuity (BCVA) was 20/40 in the left eye. Examination revealed an inferotemporal gray depression in the optic disc; OCT demonstrated submacular fluid. Serial OCTs over 19 years showed fluctuating fluid with stable vision. BCVA was 20/30 at last follow-up. A 62-year-old man presented with a central scotoma in the left eye. BCVA was 20/40 in the left eye. Examination showed an inferotemporal gray-white depression in the optic disc, and OCT revealed submacular fluid. Serial OCTs over 6 years demonstrated fluctuating fluid with preserved vision. BCVA was 20/50 at last follow-up. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;55:374-377.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"374-377"},"PeriodicalIF":0.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}