Ophthalmic surgery, lasers & imaging retina最新文献_第2页

Contrast Sensitivity Better Reflects Wide-Field Swept-Source Optical Coherence Tomography Angiography Vascular Metrics Among Healthy Eyes Compared to Visual Acuity. 与视力相比，对比敏感度能更好地反映健康眼睛的宽视场扫源光学相干断层扫描血管成像指标。

IF 0.9 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-09-01 Epub Date: 2024-06-01 DOI: 10.3928/23258160-20240411-01

Grace Baldwin, Jack Tracy, Filippos Vingopoulos, Mary Munsell, Cade Bennett, Jocelyn Marie Rodriguez, Hanna Choi, Itika Garg, Rachel Tandias, Hannah Wescott, Matthew J Finn, Peyman Razavi, Augustine Bannerman, Rebecca Zeng, Demetrios G Vavvas, Deeba Husain, Leo A Kim, Nimesh A Patel, John B Miller

{"title":"Contrast Sensitivity Better Reflects Wide-Field Swept-Source Optical Coherence Tomography Angiography Vascular Metrics Among Healthy Eyes Compared to Visual Acuity.","authors":"Grace Baldwin, Jack Tracy, Filippos Vingopoulos, Mary Munsell, Cade Bennett, Jocelyn Marie Rodriguez, Hanna Choi, Itika Garg, Rachel Tandias, Hannah Wescott, Matthew J Finn, Peyman Razavi, Augustine Bannerman, Rebecca Zeng, Demetrios G Vavvas, Deeba Husain, Leo A Kim, Nimesh A Patel, John B Miller","doi":"10.3928/23258160-20240411-01","DOIUrl":"10.3928/23258160-20240411-01","url":null,"abstract":"Background and objective: To evaluate the association between widefield swept-source optical coherence tomography angiography (WF SS-OCTA) and visual function in healthy eyes.Patients and methods: Fifty-seven eyes of 45 patients were evaluated with visual acuity (VA), contrast sensitivity (CS), and WF SS-OCTA (3 × 3, 6 × 6, and 12 × 12 mm images) on the same day. Mixed-effects multivariable regression analyses were performed.Results: Contrast sensitivity metrics, including CS between 6 to 18 cycles per degree (cpd) and area under the logarithm CS function, were significantly associated with vessel density (VD) and vessel skeletonized density (VSD), whereas VA was not. The largest effect size was between CS at 18 cpd and VD (β = 0.41, P = 0.007) and VSD (β = 0.42, P = 0.006) on 12 × 12 mm images.Conclusions: Reduced VSD and VD on WF SSOCTA was significantly associated with decreased CS, whereas VA was not. These results suggest CS could serve as a screening tool for early stage retinal and neurologic disorders. [Ophthalmic Surg Lasers Imaging Retina 2024;55:494-502.].","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Posterior Segment Manifestations of Syphilis and Correlation With Serologic Markers of Infection. 梅毒后视表现及与感染血清学标志物的相关性

IF 0.9 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-09-01 Epub Date: 2024-05-01 DOI: 10.3928/23258160-20240411-03

Kaersti L Rickels, Sayena Jabbehdari, Vignesh J Krishnan, Muhammad Z Chauhan, Marco H Ji, Pedro S Tetelbom, Ahmed B Sallam, Joseph G Chacko, Ahmad M Mansour, Sami H Uwaydat

{"title":"Posterior Segment Manifestations of Syphilis and Correlation With Serologic Markers of Infection.","authors":"Kaersti L Rickels, Sayena Jabbehdari, Vignesh J Krishnan, Muhammad Z Chauhan, Marco H Ji, Pedro S Tetelbom, Ahmed B Sallam, Joseph G Chacko, Ahmad M Mansour, Sami H Uwaydat","doi":"10.3928/23258160-20240411-03","DOIUrl":"10.3928/23258160-20240411-03","url":null,"abstract":"Background and objective: Retrospective analysis correlating serologic titers of ocular syphilis with posterior segment manifestations.Patients and methods: This study consisted of 40 patients (80 eyes imaged, 68 affected) with positive rapid plasma reagin (RPR) and Treponema Pallidum immunoglobulin G. We collected demographic and presentation data including HIV status, absolute CD4 count, RPR, cerebrospinal fluid-venereal disease research laboratory (CSF-VDRL) test, and retinal zone. We categorized imaging into syphilitic outer retinopathy (SOR), acute syphilitic posterior placoid chorioretinopathy, retinitis/chorioretinitis (RC), and papillitis. Multivariate analysis correlated HIV status, RPR, and VDRL titers with posterior segment findings and zone.Results: Mean age of 42.8 ± 10.7 years, with 70% male patients. Presenting visual acuity (logMAR) 0.66 ± 0.74 did not correlate with RPR, nor was it associated with papillitis, RC, or acute syphilitic posterior placoid chorioretinopathy. Higher RPR (≥ 1:128) positively associated with SOR (P = 0.031) and zone 1 (odds ratio [OR], 1.62; P = 0.02), but negatively associated with zone 2 (OR 0.35; P = 0.005). HIV positivity increased RC odds (OR, 4.45; P = 0.047).Conclusion: Higher RPR correlated with SOR and zone 1, whereas HIV positivity correlated with RC. [Ophthalmic Surg Lasers Imaging Retina 2024;55:511-516.].","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140944578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging Oral Pharmaceuticals for Dry Age-Related Macular Degeneration: Mechanism of Action, Current Clinical Status, and Future Directions. 治疗干性老年性黄斑变性的新兴口服药物：作用机制、临床现状和未来方向。

IF 0.9 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-09-01 Epub Date: 2024-06-01 DOI: 10.3928/23258160-20240430-02

Charles M T DeBoer, Ditte K Rasmussen, Joel A Franco, Vinit B Mahajan

{"title":"Emerging Oral Pharmaceuticals for Dry Age-Related Macular Degeneration: Mechanism of Action, Current Clinical Status, and Future Directions.","authors":"Charles M T DeBoer, Ditte K Rasmussen, Joel A Franco, Vinit B Mahajan","doi":"10.3928/23258160-20240430-02","DOIUrl":"10.3928/23258160-20240430-02","url":null,"abstract":"Dry age-related macular degeneration (AMD) has been historically managed with lifestyle modifications, monitoring for conversion to wet AMD, and vitamins. Recently there has been a flurry of research focused on discovering new targets to prevent worsening of dry AMD. In 2023, the US Food and Drug Administration approved the first two intravitreal complement inhibitors to slow the rate of geographic atrophy progression. However, serial intravitreal injections for a chronic progressive disease are burdensome for patients and have procedural risks. Therefore, there is significant research to discover novel oral medications to manage dry AMD. Several oral medications are currently in phase 2 and 3 clinical trials for dry AMD, whereas others have had recent readouts on their clinical trials and efficacy. The purpose of this review is to describe the therapeutic pathways currently being investigated and to provide an update on the clinical status of novel oral medications for the management of dry AMD. [Ophthalmic Surg Lasers Imaging Retina 2024;55:528-534.].","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigated Focal Laser of Macular Telangiectasia Type I (Adult-Onset Coats' Disease). I 型黄斑部远端血管扩张症（成人柯茨病）的导航聚焦激光。

IF 0.9 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-09-01 Epub Date: 2024-06-01 DOI: 10.3928/23258160-20240412-02

Francesca Amoroso, Alexandra Miere, Donato Colantuono, Alexandre Pedinielli, Salomon Yves Cohen, Eric Souied

{"title":"Navigated Focal Laser of Macular Telangiectasia Type I (Adult-Onset Coats' Disease).","authors":"Francesca Amoroso, Alexandra Miere, Donato Colantuono, Alexandre Pedinielli, Salomon Yves Cohen, Eric Souied","doi":"10.3928/23258160-20240412-02","DOIUrl":"10.3928/23258160-20240412-02","url":null,"abstract":"We aimed to evaluate the anatomical and functional outcome of selective photocoagulation of idiopathic macular telangiectasia type 1 by navigated focal laser (Navilas, OD-OS GmBH). Consecutive patients with idiopathic macular telangiectasia type 1 were included in the analysis. All patients were treated with navigated focal laser, planned on multimodal imaging. Seven eyes of seven patients were retrospectively analyzed. Navigated laser photocoagulation of idiopathic macular telangiectasia type 1 successfully occluded the microaneurysms, inducing regression of macular edema and exudation, significative improvement in best-corrected visual acuity at 3 (P = 0.035) and 6 months (P = 0.034) and a decrease in central macular thickness at 3 (P = 0.01) and 6 months (P = 0.01). Patients with idiopathic macular telangiectasia type 1 are ideal candidates for navigated laser treatment. Navigated focal treatment has been shown to be effective and safe in occluding aneurysmal dilations without any side effects. [Ophthalmic Surg Lasers Imaging Retina 2024;55:545-551.].","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Injectable Fluocinolone Implant for the Management of Cystoid Macular Edema in Coats' Disease. 注射用氟西诺龙植入剂用于治疗高兹病的类囊性黄斑水肿。

IF 0.9 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-08-01 DOI: 10.3928/23258160-20240621-03

Kishan G Patel, Ashkan M Abbey

引用次数: 0

A Phenomenal-Mizuo Phenomenon. 现象级的水尾现象

IF 0.9 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-08-01 DOI: 10.3928/23258160-20240621-01

Savithiri Palanivel, Aditya Maitray, Anand Rajendran

引用次数: 0

Management and Clinical Outcomes of Eyes With Posterior Segment Intraocular Foreign Bodies Seen at a Tertiary Referral Center. 在一家三级转诊中心就诊的眼球后段眼内异物患者的处理方法和临床结果。

IF 0.9 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-08-01 Epub Date: 2024-05-01 DOI: 10.3928/23258160-20240402-01

Puren Isik, Selcuk Sizmaz, Ebru Esen, Mustafa Aksoy, Burcu Cam, Nihal Demircan, Ferenc Kuhn, Hulya Binokay

{"title":"Management and Clinical Outcomes of Eyes With Posterior Segment Intraocular Foreign Bodies Seen at a Tertiary Referral Center.","authors":"Puren Isik, Selcuk Sizmaz, Ebru Esen, Mustafa Aksoy, Burcu Cam, Nihal Demircan, Ferenc Kuhn, Hulya Binokay","doi":"10.3928/23258160-20240402-01","DOIUrl":"10.3928/23258160-20240402-01","url":null,"abstract":"Background and objective: This study aimed to identify the prognostic factors regarding the visual and anatomic outcomes of eyes with posterior segment intraocular foreign body (PS-IOFB).Patients and methods: The medical records of 95 patients who underwent pars plana vitrectomy and PS-IOFB removal between 2004 and 2021 were retrospectively reviewed. Data on anatomical and visual outcomes, as well as preoperative, intraoperative, and postoperative variables were statistically analyzed.Results: The mean age of the patients was 31.9 ± 12.3 years. The mean follow-up time was 21.9 ± 28.3 months. The median time interval from trauma to IOFB removal was 9 days. In univariate analysis, there was a positive correlation between initial visual acuity (VA) and final VA (P < 0.001). A higher ocular trauma score (OTS) was significantly associated with both anatomical and functional success (P < 0.001). Linear regression analysis showed that OTS was not superior to initial VA in predicting final VA (r = 0.625 vs r = -0.601). Anatomic and functional outcomes were not affected by the injury site, nature of PS-IOFB, or timing of PS-IOFB removal (P > 0.05 for all). Subretinal IOFB location, the need for silicone oil tamponade, and endophthalmitis (P = 0.005, P < 0.001, P = 0.044, respectively) were risk factors for poor visual outcome.Conclusions: The initial VA, the extent of the initial ocular damage, and the presence of endophthalmitis are important prognostic factors for functional success. [Ophthalmic Surg Lasers Imaging Retina 2024;55:434-442.].","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140944387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Pars Plana Vitrectomy With and Without Supplemental Scleral Buckle for the Repair of Rhegmatogenous Detachment Due to Inferior Retinal Breaks: A Systematic Review. 评估有无辅助巩膜扣带的玻璃体旁切除术，以修复因视网膜下部破损导致的风湿性脱离：系统回顾。

IF 0.9 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-08-01 DOI: 10.3928/23258160-20240801-02

Eleanor R Lena, Nikhil S Patil, Marko M Popovic, Arshia Eshtiaghi, Arjan S Dhoot, Rajeev H Muni, Peter J Kertes

{"title":"Evaluation of Pars Plana Vitrectomy With and Without Supplemental Scleral Buckle for the Repair of Rhegmatogenous Detachment Due to Inferior Retinal Breaks: A Systematic Review.","authors":"Eleanor R Lena, Nikhil S Patil, Marko M Popovic, Arshia Eshtiaghi, Arjan S Dhoot, Rajeev H Muni, Peter J Kertes","doi":"10.3928/23258160-20240801-02","DOIUrl":"https://doi.org/10.3928/23258160-20240801-02","url":null,"abstract":"In this systematic review, the efficacy of scleral buckle (SB) with pars plana vitrectomy (PPV) was compared to PPV alone in eyes with rhegmatogenous retinal detachment (RRD) due to inferior retinal breaks (IRB). Measured outcomes included final best-corrected visual acuity (BCVA), anatomic success, and complication rates in randomized controlled trials and observational studies from 2000 to 2022. Among four studies (696 eyes), three studies demonstrated no significant difference between PPV and PPV/SB for final BCVA, whereas one study reported better BCVA with added SB. PPV/SB yielded comparable single-surgery anatomical success (SSAS) and final anatomical success (FAS) in three studies relative to PPV alone (P < 0.05); however, one study reported better SSAS with added SB. Stratifying by lens status revealed a SSAS benefit with PPV/SB in phakic eyes (P = 0.046). No significant difference was seen in complication rates. In conclusion, PPV and PPV/SB were associated with similar functional outcomes and risk profile, whereas SSAS may be improved with PPV/SB in phakic eyes with RRD due to IRB. [Ophthalmic Surg Lasers Imaging Retina 2024;55:XX-XX.].","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thrombotic Microangiopathy Following Hematopoietic Stem Cell Transplantation: A Case of Purtscher-like Retinopathy. 造血干细胞移植后的血栓性微血管病：一例紫癜样视网膜病变。

IF 0.9 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-08-01 DOI: 10.3928/23258160-20240528-05

Okyanus Bulut, Gulcihan Ozek, Filiz Afrashi, Cumali Degirmenci

引用次数: 0

Macular Hole Self Closure While Awaiting Pre-operative Clearance. 在等待术前检查的同时自行封闭黄斑孔

IF 0.9 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-08-01 DOI: 10.3928/23258160-20240729-01

Michael Javaheri, Angela J Oh, Pradeep S Prasad

{"title":"Macular Hole Self Closure While Awaiting Pre-operative Clearance.","authors":"Michael Javaheri, Angela J Oh, Pradeep S Prasad","doi":"10.3928/23258160-20240729-01","DOIUrl":"https://doi.org/10.3928/23258160-20240729-01","url":null,"abstract":"A 69-year-old white woman with a history of vitreomacular traction (VMT) presented with a 2-week history of visual loss in the right eye. Visual acuity, with correction, measured 20/200 in the right eye. Examination revealed a partial posterior vitreous detachment and a stage 2 full-thickness macular hole (FTMH). Spectral-domain optical coherence tomography (SD-OCT) testing confirmed a stage 2 FTMH with VMT. Pars plana vitrectomy without internal limiting membrane peeling was planned and the patient was sent for preoperative clearance, where she was diagnosed with atrial fibrillation and wanted to delay surgery. Two months later, the patient returned for follow-up with a visual acuity of 20/80, a closed macular hole, and an incomplete posterior vitreous detachment in her right eye. Four months later, the patient exhibited a completely closed FTMH with a visual acuity of 20/30. Spontaneous resolution of FTMHs (stages 2 to 4) in the adult population is an extremely rare event, occurring in less than 4% of affected eyes. We describe a patient with a stage 2 FTMH who exhibited spontaneous resolution due to the resolution of VMT while awaiting preoperative clearance. [Ophthalmic Surg Lasers Imaging Retina 2024;55:XX-XX.].","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0