Ophthalmic surgery, lasers & imaging retina最新文献

{"title":"RWC Update: Office-Based Vitrectomy: Is It Ready for Mainstream Practice?; Autologous Retinal Transplantation Using a Retinotomy Edge Graft for Macular Hole During Complex PVR Retinal Detachment Repair; Morning Glory Disc and Choroidal Coloboma With Pseudoduplicated Optic Nerve.","authors":"Ashish Sharma, Lihteh Wu, Steven Bloom, Paulo Stanga, Andrew Chang, Marcelo Zas, Sean Berkowitz, Ananth Sastry, Shraddha Raj Shrivastava, Manish Nagpal, Kourous A Rezaei","doi":"10.3928/23258160-20260806-01","DOIUrl":"https://doi.org/10.3928/23258160-20260806-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":"57 9","pages":"547-550"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging Artifact Mimicking Retinal Detachment in Retinopathy of Prematurity.","authors":"Dave Young, Eugenia Paula Custo Greig, Akwasi A Ahmed, Samuel Bondzie, Melissa Y Yuan, Sarthak V Shah, Arthur R Brant, Darius M Moshfeghi","doi":"10.3928/23258160-20260514-02","DOIUrl":"10.3928/23258160-20260514-02","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"610-611"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148448124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predominantly Nonexudative Nature of Choroidal Neovascularization in Central Serous Chorioretinopathy.","authors":"Dmitrii S Maltsev, Alexei N Kulikov, Yana A Kalinicheva","doi":"10.3928/23258160-20260720-02","DOIUrl":"10.3928/23258160-20260720-02","url":null,"abstract":"<p><strong>Background and objective: </strong>The aim of this study was to evaluate the characteristics of choroidal neovascularization (CNV) in central serous chorioretinopathy (CSCR).</p><p><strong>Patients and methods: </strong>Patients with unilateral CSCR complicated by the double-layer sign were enrolled in this retrospective cohort study. Cases with a neovascular network visible on optical coherence tomography angiography were selected for the analysis.</p><p><strong>Results: </strong>Eighty-two patients (58.7 ± 10.5 years, 39 women [47.6%]) were included. Among 34 eyes receiving no anti-vascular endothelial growth factor therapy (median follow-up 16.0 [IQR 9.8 to 18.8] months), CNV area changed from 0.62 (0.51 to 1.1) to 0.78 (IQR 0.50 to 1.0) mm² (<i>P</i> = .2) and vascular density changed from 57.8 ± 11.6 to 55.9 ± 11.1% (<i>P</i> = .58). In multivariable analysis, a negative correlation was found between CNV area and central retinal thickness (<i>P</i> = .03). Nonexudative CNV in fellow eyes was found in 16/82 patients (19.5%).</p><p><strong>Conclusion: </strong>Several morphological and clinical characteristics as well as the stationary character suggest that in this specific subset of neovascular CSCR patients CNV has predominantly nonexudative nature.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"596-603"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148840905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Potentially Sight-Threatening Pathology Detected by Non-Mydriatic Fundus Photography in a National Diabetic Screening Platform.","authors":"Faiza Sarwar, Caitlin Kristoff, Shawn Kavoussi","doi":"10.3928/23258160-20260717-02","DOIUrl":"10.3928/23258160-20260717-02","url":null,"abstract":"<p><strong>Background and objective: </strong>Hundreds, if not thousands, of non-mydriatic fundus images are acquired in primary care offices daily and uploaded for remote grading by ophthalmologists, retina specialists, and/or artificial intelligence. No prior studies of this magnitude have explored the yield of sight-threatening pathology identified on these platforms. The goal of this study is to report on the prevalence of potentially sight-threatening pathology during a 9-year experience with a single national telemedicine platform.</p><p><strong>Patients and methods: </strong>This was a multicenter, non-interventional, non-masked, non-randomized, retrospective review of 1,190,754 consecutive gradable bilateral fundus exams obtained on non-mydriatic fundus cameras in the primary care setting and uploaded to a national platform. All images were interpreted by board-certified ophthalmologists and/or fellowship-trained retinal specialists.</p><p><strong>Results: </strong>In total, 44% of gradable exams were obtained on the Center Vue DRS camera, 38% on the Volk Pictor Plus, and the remainder on other cameras. Of these, 381,023 exams (32%) had evidence of pathology. Suspected moderate, severe, and proliferative diabetic retinopathy were present on 101,714 (9%), 23,988 (2%), and 30,515 (3%) exams, respectively. Macular edema was present on 27,712 exams (2%). Epiretinal membrane and age-related macular degeneration (total of exudative and dry) were present on 14,306 (1%) and 36,298 (3%) exams, respectively. Suspected glaucoma was present on 70,154 exams (6%). Papilledema, melanoma, posterior uveitis, and retinal detachment were reported in an \"other pathology\" category that included 116,762 exams (10%).</p><p><strong>Conclusion: </strong>Routine non-mydriatic fundus screening in the primary care setting detects diabetic and non-diabetic pathology in approximately one-third of patients.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"591-594"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148796310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of the Telemedicine Retinopathy of Prematurity Severity Score in a Tertiary Neonatal Intensive Care Unit.","authors":"Katherine M Overbey, Kwabena Onwona-Agyeman, Sarthak V Shah, Cindy S Zhao, Samuel Bondzie, Imoro Z Braimah, Arthur R Brant, Hanks Wallace, Ashna Ahya, Dave Young, Geoffrey C Tabin, Darius M Moshfeghi","doi":"10.3928/23258160-20260619-01","DOIUrl":"10.3928/23258160-20260619-01","url":null,"abstract":"<p><strong>Background and objective: </strong>Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. ROP management needs multidisciplinary coordination and clear communication of disease severity. This study aims to evaluate the usability of the Telemedicine ROP Severity Score (tROP-SS) among nonophthalmologists.</p><p><strong>Patients and methods: </strong>Twenty-three neonatal intensive care unit (NICU) staff completed a questionnaire with terminology from the International Classification for ROP, Third Edition (ICROP3) or tROP-SS. Participants were assessed on ease of use, identification of progression or regression, and communication with families. Accuracy, number of clicks, and time per question were recorded.</p><p><strong>Results: </strong>Accuracy was higher using tROP-SS terminology vs ICROP3 (76.5% ± 29.2% vs 51.7% ± 20.1%; <i>P</i> = .002). Participants preferred tROP-SS across all subjective domains (<i>P</i> < .001), citing improved understandability, disease assessment, and communication.</p><p><strong>Conclusion: </strong>The tROP-SS enhances both accuracy and usability for NICU staff. By simplifying complex classification into a single score, tROP-SS supports multidisciplinary care.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"584-589"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148796258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging Biomarkers in the Management of Retinal Diseases: Clinical Applications and Future Directions.","authors":"Hannah Khan, Dhruv P Patel, Seenu M Hariprasad, Arshad M Khanani, Aamir A Aziz","doi":"10.3928/23258160-20260722-01","DOIUrl":"10.3928/23258160-20260722-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"552-556"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148796237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photographic Artifact Resembling International Classification of Retinopathy of Prematurity Stage One and Two Description.","authors":"Kyle Hansen, Sarthak V Shah, Arthur Brant, Cindy Zhao, Darius M Moshfeghi","doi":"10.3928/23258160-20260526-02","DOIUrl":"10.3928/23258160-20260526-02","url":null,"abstract":"<p><p>This report presents a retrospective case series of fundus photography artifacts encountered during telemedicine-based retinopathy of prematurity (ROP) screenings that closely resemble stage 1 and 2 ROP as defined by the International Classification of Retinopathy of Prematurity (ICROP). Images were obtained from preterm infants undergoing routine ROP screening through Stanford University Network for Diagnosis of Retinopathy of Prematurity (SUNDROP) and TeleROP telemedicine screening programs using the RetCam Envision 130° pediatric camera. Photographs taken by trained neonatal intensive care unit nurses were securely transmitted to ROP specialists for interpretation. Review of the photographs revealed several artifacts that appeared similar to early-stage ROP. Artifacts notably shifted position across multiple redundant images and retinal vessels extended beyond the demarcation line, confirming their nonpathologic nature. Awareness of these imaging artifacts is critical for ophthalmologists involved in ROP diagnosis and management. Comparing multiple images from slightly different angles allows graders to reliably distinguish artifacts from true ROP pathology, thereby avoiding misdiagnosis and unnecessary interventions.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"607-609"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148448098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal and Choroidal Vascular Alterations on Swept-Source Optical Coherence Tomography Angiography in Adults With a History of Retinopathy of Prematurity.","authors":"Ioanna Ploumi, Kailynn Barton, Celine Chaaya, Kayla Nodecker, Sandra Hoyek, Jooyoung Chang, Itika Garg, Xinyi Ding, Ying Zhu, Francesco Romano, Konstantinos G Baroutis, Lilly Krupp, Graham Calton, Gates Griffin, John B Miller, Nimesh A Patel","doi":"10.3928/23258160-20260717-01","DOIUrl":"10.3928/23258160-20260717-01","url":null,"abstract":"<p><strong>Background and objective: </strong>This study aimed to characterize the central retinal and choroidal vasculature in adults with a history of retinopathy of prematurity (ROP).</p><p><strong>Patients and methods: </strong>In this cross-sectional study, adults with history of ROP were compared to full-term controls using macular 6 × 6-mm and 12 × 12-mm swept-source optical coherence tomography angiography (OCTA) (PLEX Elite 9000). Vessel density (VD) and vessel skeletonized density (VSD) were quantified in the superficial capillary plexus, deep capillary plexus (DCP), and whole retina. Foveal avascular zone (FAZ) metrics, mean choroidal thickness (MCT), and choroidal vascularity index (CVI) were also analyzed. Linear mixed-effects models adjusted for age and nesting estimated group differences for global and sector-level outcomes. A secondary exploratory analysis was conducted to compare treated versus untreated ROP eyes.</p><p><strong>Results: </strong>Twenty-three eyes from 13 adults with ROP and 19 eyes from 15 controls were included. ROP eyes showed significantly lower VD and VSD across all layers on both scan sizes (all <i>P</i> < .05), with largest effects in the DCP. Sector maps revealed widespread deficits that preferentially involved inferior and temporal regions. On 6 × 6-mm scans, FAZ area, circularity, and perimeter were smaller in ROP (all <i>P</i> < .05). On 12 × 12-mm scans, CVI was reduced in ROP (<i>P</i> = .048), while MCT did not differ. Previously treated ROP eyes had lower VD and VSD compared to untreated ROP eyes (all <i>P</i> < .05).</p><p><strong>Conclusion: </strong>Adults with a history of ROP exhibit persistent retinal microvascular loss and decreased choroidal vascularity. OCTA can be used to assess subclinical abnormalities and as a future outcome measure when comparing ROP treatment modalities.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"529-536"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statin Use and the Risk of Proliferative Vitreoretinopathy in Eyes Undergoing Rhegmatogenous Retinal Detachment Repair.","authors":"Sidra Zafar, Nitika Aggarwal, Sudheshna Vemula, Turner Wibbelsman, Josee Winsor, Nick Boucher, Ajay E Kuriyan, Yoshihiro Yonekawa","doi":"10.3928/23258160-20260618-01","DOIUrl":"10.3928/23258160-20260618-01","url":null,"abstract":"<p><strong>Background and objective: </strong>This study aimed to evaluate the association between statin use and frequency of proliferative vitreoretinopathy (PVR) and return to the operating room in eyes undergoing rhegmatogenous retinal detachment (RRD) repair.</p><p><strong>Patients and methods: </strong>This was a retrospective study of all patients ≥18 years of age who underwent RRD repair between January 2015 and November 2024, identified in the Vestrum Health Retina Database.</p><p><strong>Results: </strong>A total of 54,876 eyes were included in the final analysis, of which 17,922 (33%) were taking statins. The frequency of PVR development within 90 days following primary RRD repair was significantly lower in the statin group compared to the non-statin group (6.67% vs. 8.17%, <i>P</i> < .001). In a multivariate regression analysis adjusted for age, sex, smoking history, lens status, diabetes, and surgery type, statin use was independently associated with a decreased likelihood of PVR (odds ratio: 0.70, 95% CI: 0.66 to 0.75).</p><p><strong>Conclusion: </strong>Statin use was associated with a significantly lower risk for PVR formation and return to the operating room following primary RRD repair.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"523-528"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148679394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expert Opinion: Management of Intraocular Inflammation and Vasculitis After Intravitreal Pegcetacoplan for Geographic Atrophy.","authors":"Thomas A Albini, Steven Yeh, Carl D Regillo, Roy Schwartz, Philip J Ferrone, Caroline R Baumal, Charles C Wykoff","doi":"10.3928/23258160-20260521-03","DOIUrl":"10.3928/23258160-20260521-03","url":null,"abstract":"<p><strong>Background and objective: </strong>This expert opinion review is intended to provide guidelines for diagnosis and management of intraocular inflammation (IOI) and vasculitis following pegcetacoplan.</p><p><strong>Patients and methods: </strong>A case series of all post-marketing reports classified by experts as definite or suspected vasculitis over an 18-month period was assessed.</p><p><strong>Results: </strong>A total of 306,000 pegcetacoplan intravitreal injections were given in the real world between March 1, 2023, and August 31, 2024. Twenty-four eyes from 22 patients (mean age 76 years, 59% female) with definite or suspected vasculitis were evaluated. Comorbidities included hypertension (55%), hypothyroidism (27%), and recent COVID-19 infection (14%). Twelve eyes were classified as vasculitis with occlusion, seven as vasculitis without occlusion, and five as suspected vasculitis. Median time from intravitreal injection to symptoms was 10 days and 88% (<i>n</i> = 21) occurred after the first injection. Symptoms included reduced vision (71%), eye pain (33%), and elevated intraocular pressure (50%). All patients received corticosteroids and 29% received antibiotics. At last follow-up, six eyes recovered visual acuity to within one line of baseline, seven lost between 2 to 5 lines, and 11 lost 6 lines or more.</p><p><strong>Conclusion: </strong>While IOI and vasculitis are rare, patients can be educated to call a retina specialist promptly if symptoms or any vision loss develop, especially within the 2 weeks following the first injection. In addition to excluding an infectious etiology, individualized management with multiroute corticosteroids can be considered.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"492-498"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148448086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}