Ophthalmic surgery, lasers & imaging retina最新文献

{"title":"Utility of the Telemedicine Retinopathy of Prematurity Severity Score in a Tertiary Neonatal Intensive Care Unit.","authors":"Katherine M Overbey, Kwabena Onwona-Agyeman, Sarthak V Shah, Cindy S Zhao, Samuel Bondzie, Imoro Z Braimah, Arthur R Brant, Hanks Wallace, Ashna Ahya, Dave Young, Geoffrey C Tabin, Darius M Moshfeghi","doi":"10.3928/23258160-20260619-01","DOIUrl":"10.3928/23258160-20260619-01","url":null,"abstract":"<p><strong>Background and objective: </strong>Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. ROP management needs multidisciplinary coordination and clear communication of disease severity. This study aims to evaluate the usability of the Telemedicine ROP Severity Score (tROP-SS) among nonophthalmologists.</p><p><strong>Patients and methods: </strong>Twenty-three neonatal intensive care unit (NICU) staff completed a questionnaire with terminology from the International Classification for ROP, Third Edition (ICROP3) or tROP-SS. Participants were assessed on ease of use, identification of progression or regression, and communication with families. Accuracy, number of clicks, and time per question were recorded.</p><p><strong>Results: </strong>Accuracy was higher using tROP-SS terminology vs ICROP3 (76.5% ± 29.2% vs 51.7% ± 20.1%; <i>P</i> = .002). Participants preferred tROP-SS across all subjective domains (<i>P</i> < .001), citing improved understandability, disease assessment, and communication.</p><p><strong>Conclusion: </strong>The tROP-SS enhances both accuracy and usability for NICU staff. By simplifying complex classification into a single score, tROP-SS supports multidisciplinary care.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"584-589"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148796258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging Biomarkers in the Management of Retinal Diseases: Clinical Applications and Future Directions.","authors":"Hannah Khan, Dhruv P Patel, Seenu M Hariprasad, Arshad M Khanani, Aamir A Aziz","doi":"10.3928/23258160-20260722-01","DOIUrl":"10.3928/23258160-20260722-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"552-556"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148796237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photographic Artifact Resembling International Classification of Retinopathy of Prematurity Stage One and Two Description.","authors":"Kyle Hansen, Sarthak V Shah, Arthur Brant, Cindy Zhao, Darius M Moshfeghi","doi":"10.3928/23258160-20260526-02","DOIUrl":"10.3928/23258160-20260526-02","url":null,"abstract":"<p><p>This report presents a retrospective case series of fundus photography artifacts encountered during telemedicine-based retinopathy of prematurity (ROP) screenings that closely resemble stage 1 and 2 ROP as defined by the International Classification of Retinopathy of Prematurity (ICROP). Images were obtained from preterm infants undergoing routine ROP screening through Stanford University Network for Diagnosis of Retinopathy of Prematurity (SUNDROP) and TeleROP telemedicine screening programs using the RetCam Envision 130° pediatric camera. Photographs taken by trained neonatal intensive care unit nurses were securely transmitted to ROP specialists for interpretation. Review of the photographs revealed several artifacts that appeared similar to early-stage ROP. Artifacts notably shifted position across multiple redundant images and retinal vessels extended beyond the demarcation line, confirming their nonpathologic nature. Awareness of these imaging artifacts is critical for ophthalmologists involved in ROP diagnosis and management. Comparing multiple images from slightly different angles allows graders to reliably distinguish artifacts from true ROP pathology, thereby avoiding misdiagnosis and unnecessary interventions.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"607-609"},"PeriodicalIF":1.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148448098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal and Choroidal Vascular Alterations on Swept-Source Optical Coherence Tomography Angiography in Adults With a History of Retinopathy of Prematurity.","authors":"Ioanna Ploumi, Kailynn Barton, Celine Chaaya, Kayla Nodecker, Sandra Hoyek, Jooyoung Chang, Itika Garg, Xinyi Ding, Ying Zhu, Francesco Romano, Konstantinos G Baroutis, Lilly Krupp, Graham Calton, Gates Griffin, John B Miller, Nimesh A Patel","doi":"10.3928/23258160-20260717-01","DOIUrl":"10.3928/23258160-20260717-01","url":null,"abstract":"<p><strong>Background and objective: </strong>This study aimed to characterize the central retinal and choroidal vasculature in adults with a history of retinopathy of prematurity (ROP).</p><p><strong>Patients and methods: </strong>In this cross-sectional study, adults with history of ROP were compared to full-term controls using macular 6 × 6-mm and 12 × 12-mm swept-source optical coherence tomography angiography (OCTA) (PLEX Elite 9000). Vessel density (VD) and vessel skeletonized density (VSD) were quantified in the superficial capillary plexus, deep capillary plexus (DCP), and whole retina. Foveal avascular zone (FAZ) metrics, mean choroidal thickness (MCT), and choroidal vascularity index (CVI) were also analyzed. Linear mixed-effects models adjusted for age and nesting estimated group differences for global and sector-level outcomes. A secondary exploratory analysis was conducted to compare treated versus untreated ROP eyes.</p><p><strong>Results: </strong>Twenty-three eyes from 13 adults with ROP and 19 eyes from 15 controls were included. ROP eyes showed significantly lower VD and VSD across all layers on both scan sizes (all <i>P</i> < .05), with largest effects in the DCP. Sector maps revealed widespread deficits that preferentially involved inferior and temporal regions. On 6 × 6-mm scans, FAZ area, circularity, and perimeter were smaller in ROP (all <i>P</i> < .05). On 12 × 12-mm scans, CVI was reduced in ROP (<i>P</i> = .048), while MCT did not differ. Previously treated ROP eyes had lower VD and VSD compared to untreated ROP eyes (all <i>P</i> < .05).</p><p><strong>Conclusion: </strong>Adults with a history of ROP exhibit persistent retinal microvascular loss and decreased choroidal vascularity. OCTA can be used to assess subclinical abnormalities and as a future outcome measure when comparing ROP treatment modalities.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"529-536"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Statin Use and the Risk of Proliferative Vitreoretinopathy in Eyes Undergoing Rhegmatogenous Retinal Detachment Repair.","authors":"Sidra Zafar, Nitika Aggarwal, Sudheshna Vemula, Turner Wibbelsman, Josee Winsor, Nick Boucher, Ajay E Kuriyan, Yoshihiro Yonekawa","doi":"10.3928/23258160-20260618-01","DOIUrl":"10.3928/23258160-20260618-01","url":null,"abstract":"<p><strong>Background and objective: </strong>This study aimed to evaluate the association between statin use and frequency of proliferative vitreoretinopathy (PVR) and return to the operating room in eyes undergoing rhegmatogenous retinal detachment (RRD) repair.</p><p><strong>Patients and methods: </strong>This was a retrospective study of all patients ≥18 years of age who underwent RRD repair between January 2015 and November 2024, identified in the Vestrum Health Retina Database.</p><p><strong>Results: </strong>A total of 54,876 eyes were included in the final analysis, of which 17,922 (33%) were taking statins. The frequency of PVR development within 90 days following primary RRD repair was significantly lower in the statin group compared to the non-statin group (6.67% vs. 8.17%, <i>P</i> < .001). In a multivariate regression analysis adjusted for age, sex, smoking history, lens status, diabetes, and surgery type, statin use was independently associated with a decreased likelihood of PVR (odds ratio: 0.70, 95% CI: 0.66 to 0.75).</p><p><strong>Conclusion: </strong>Statin use was associated with a significantly lower risk for PVR formation and return to the operating room following primary RRD repair.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"523-528"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148679394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expert Opinion: Management of Intraocular Inflammation and Vasculitis After Intravitreal Pegcetacoplan for Geographic Atrophy.","authors":"Thomas A Albini, Steven Yeh, Carl D Regillo, Roy Schwartz, Philip J Ferrone, Caroline R Baumal, Charles C Wykoff","doi":"10.3928/23258160-20260521-03","DOIUrl":"10.3928/23258160-20260521-03","url":null,"abstract":"<p><strong>Background and objective: </strong>This expert opinion review is intended to provide guidelines for diagnosis and management of intraocular inflammation (IOI) and vasculitis following pegcetacoplan.</p><p><strong>Patients and methods: </strong>A case series of all post-marketing reports classified by experts as definite or suspected vasculitis over an 18-month period was assessed.</p><p><strong>Results: </strong>A total of 306,000 pegcetacoplan intravitreal injections were given in the real world between March 1, 2023, and August 31, 2024. Twenty-four eyes from 22 patients (mean age 76 years, 59% female) with definite or suspected vasculitis were evaluated. Comorbidities included hypertension (55%), hypothyroidism (27%), and recent COVID-19 infection (14%). Twelve eyes were classified as vasculitis with occlusion, seven as vasculitis without occlusion, and five as suspected vasculitis. Median time from intravitreal injection to symptoms was 10 days and 88% (<i>n</i> = 21) occurred after the first injection. Symptoms included reduced vision (71%), eye pain (33%), and elevated intraocular pressure (50%). All patients received corticosteroids and 29% received antibiotics. At last follow-up, six eyes recovered visual acuity to within one line of baseline, seven lost between 2 to 5 lines, and 11 lost 6 lines or more.</p><p><strong>Conclusion: </strong>While IOI and vasculitis are rare, patients can be educated to call a retina specialist promptly if symptoms or any vision loss develop, especially within the 2 weeks following the first injection. In addition to excluding an infectious etiology, individualized management with multiroute corticosteroids can be considered.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"492-498"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148448086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Insulin-Like Growth Factor-1 and Insulin Resistance in Patients With Central Serous Chorioretinopathy.","authors":"Naciye Tora, Günhal Şatırtav, Filiz Alkan Baylan, Hürkan Kerimoğlu, Mehmet Okka, Ali Tezcan","doi":"10.3928/23258160-20260528-01","DOIUrl":"10.3928/23258160-20260528-01","url":null,"abstract":"<p><strong>Background and objective: </strong>This study aimed to investigate serum levels of insulin-like growth factor-1 (IGF-1) and its association with parameters related to insulin resistance, in patients diagnosed with central serous chorioretinopathy (CSCR).</p><p><strong>Patients and methods: </strong>In this cross-sectional comparative study, patients were classified as simple (<i>n</i> = 30) or complex (<i>n</i> = 25) CSCR based on multimodal imaging findings. Following a comprehensive ophthalmologic examination, fasting venous blood samples were collected for the biochemical analysis of glucose, insulin, IGF-1, C-reactive protein (CRP), and glycated hemoglobin (HbA1c). Subsequently, body mass index (BMI) and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) values were calculated for each participant.</p><p><strong>Results: </strong>Mean serum IGF-1 levels were significantly higher in simple and complex CSCR groups compared with controls (<i>P</i> < .05). No significant differences were observed among the groups in glucose, HbA1c, CRP, BMI, or HOMA-IR (<i>P</i> > .05).</p><p><strong>Conclusion: </strong>Elevated IGF-1 levels in CSCR patients suggest that this growth factor may contribute to disease pathogenesis through mechanisms involving choroidal vascular permeability and retinal endothelial activity.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"499-503"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148448725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Observation Without Vitrectomy in Penetrating Open-Globe Injury With Retinal Strike Sites in Young Patients.","authors":"Isaac D Bleicher, Marisa Tieger, Celine Chaaya, Dean Eliott, Ankoor S Shah, Ivana K Kim, Nimesh A Patel","doi":"10.3928/23258160-20260720-01","DOIUrl":"10.3928/23258160-20260720-01","url":null,"abstract":"<p><p>The aim of this study was to describe outcomes of non-operative management of retinal strike sites in penetrating open-globe injury with formed vitreous. A retrospective series of patients with open-globe injuries with retinal strike sites and without retained foreign body. Primary repair and follow-up were conducted at Mass Eye and Ear with examination, fundus photographs, and B-scan ultrasonography as indicated by the clinical course. Patients did not undergo secondary vitrectomy for management of retinal strike sites. A total of three cases were included. Two patients were managed by observation; one received laser retinopexy. Retinal detachment did not develop in any patient with follow-ups of 2 years, 3 years, and 18 months, respectively. Two patients, one of whom received laser retinopexy, developed mild, non-progressive vitreous traction adjacent to the strike site. Two patients achieved final visual acuity of 20/20; one patient had final visual acuity of 20/40 due to corneal astigmatism. All patients were younger than 25 years of age and did not have posterior vitreous detachment (PVD) through at least 18 months follow-up. In three cases of penetrating injury into vitreous with a retinal strike site, young patients without a PVD maintained good anatomic and visual outcomes without vitrectomy. Future work should evaluate how age and vitreous status might influence indications for vitrectomy.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"538-543"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148679389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late Retinal Detachments in Retinopathy of Prematurity.","authors":"Celine Chaaya, Ryan S Meshkin, Ayush Parikh, Srujay Pandiri, Sandra Hoyek, Francisco Altamirano-Lamarque, Shizuo Mukai, Nimesh A Patel","doi":"10.3928/23258160-20260529-01","DOIUrl":"10.3928/23258160-20260529-01","url":null,"abstract":"<p><strong>Background and objective: </strong>This study aimed to investigate the presenting characteristics and outcomes of ROP patients with late retinal detachment (RD).</p><p><strong>Patients and methods: </strong>A retrospective chart review was performed for patients with ROP who presented with a late RD, occurring at least 2 years after initial ROP diagnosis. Demographic information, visual outcomes, and RD characteristics were obtained.</p><p><strong>Results: </strong>A total of 38 patients with a history of ROP who presented with a late RD were included (57.9% males). The median birth weight was 851.5 g and median gestational age at birth was 26.5 weeks. The median age at presentation for RD was 19 years. More than half of the RDs were diagnosed incidentally on routine examination, and 51.7% had macula-off RD. Fifty percent of patients had a rhegmatogenous RD, 35.3% had tractional RD, and 14.7% had combined rhegmatogenous and tractional RD. The majority of patients (78%) underwent surgical intervention for RD repair with either combined pars plana vitrectomy and scleral buckle (46.9%), scleral buckle alone (34.4%), or pars plana vitrectomy alone (18.7%), and 22% were observed due to guarded prognosis. The median logMAR vision was 1.8 at presentation and 1.18 at final follow-up. Redetachment occurred in 23.6% of patients, of whom 88.9% had additional surgery.</p><p><strong>Conclusion: </strong>Late RDs can develop in the setting of ROP and usually occur in young adulthood. More than one half of patients were found asymptomatically on routine examination and had macula-off RD. Many required complex surgery with silicone oil. Long-term follow-up for ROP patients may be indicated to monitor for progressive traction and retinal breaks.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"505-510"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148605954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Home Optical Coherence Tomography Monitoring in Neovascular AMD: The SCANLY System.","authors":"Maxwell Prenner, Howard F Fine, Eric Nudleman","doi":"10.3928/23258160-20260618-03","DOIUrl":"10.3928/23258160-20260618-03","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"484"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148679346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}