Kensington A Hatcher, Birva K Shah, Song Yu, Caroline R Baumal, Srinivas Sadda
{"title":"Outer Retinal Tubulation and Vision in Geographic Atrophy: A Natural History Analysis From the Phase 3 OAKS and DERBY Trials.","authors":"Kensington A Hatcher, Birva K Shah, Song Yu, Caroline R Baumal, Srinivas Sadda","doi":"10.3928/23258160-20250108-02","DOIUrl":"10.3928/23258160-20250108-02","url":null,"abstract":"<p><strong>Background and objective: </strong>Outer retinal tubulation (ORT) is an optical coherence tomography finding in numerous chronic retinal diseases, including geographic atrophy (GA). The objective of this study was to evaluate longitudinal best-corrected visual acuity (BCVA) outcomes in patients with GA comparing eyes with and without ORT at baseline.</p><p><strong>Patients and methods: </strong>This post hoc longitudinal analysis assessed 300 eyes randomized to sham treatment in the phase 3 OAKS and DERBY trials. Mean change in BCVA over 24 months was calculated, comparing lesions with ORT versus those without ORT at baseline.</p><p><strong>Results: </strong>Ninety-six (32.0%) of the 300 sham-treated eyes with GA had an ORT at baseline. Eyes with ORT at baseline lost on average 5.5 fewer Early Treatment Diabetic Retinopathy Study letters than eyes without ORT.</p><p><strong>Conclusion: </strong>Sham-treated eyes with ORT at baseline had less loss of BCVA over 24 months than eyes without ORT. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:228-230.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"228-230"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Landon J Rohowetz, Prashanth G Iyer, Noy Ashkenazy, Kenneth C Fan, Rita Laiginhas, Yingying Shi, Jeremy Liu, Philip Rosenfeld, Harry W Flynn
{"title":"Tractional Retinoschisis in Proliferative Diabetic Retinopathy Imaged With Swept-Source Optical Coherence Tomography Angiography.","authors":"Landon J Rohowetz, Prashanth G Iyer, Noy Ashkenazy, Kenneth C Fan, Rita Laiginhas, Yingying Shi, Jeremy Liu, Philip Rosenfeld, Harry W Flynn","doi":"10.3928/23258160-20241101-04","DOIUrl":"10.3928/23258160-20241101-04","url":null,"abstract":"<p><p>Tractional retinoschisis (TRS) secondary to proliferative diabetic retinopathy (PDR) may be differentiated from tractional retinal detachment (TRD) by its characteristically nonprogressive course. The purpose of the current study was to describe the use of swept-source optical coherence tomography angiography (SS-OCTA) in the diagnosis and monitoring of TRS secondary to PDR. Retrospective, consecutive case series of patients with TRS secondary to PDR are featured. Clinical notes, fundus photography, and SS-OCTA images are reviewed. The study comprised three eyes of three patients with PDR and TRS. Visual acuity and anatomic features on SS-OCTA were stable in all patients at one year or more of follow-up. Tractional retinoschisis secondary to PDR is typically nonprogressive and may be observed without surgery. SS-OCTA serves as a noninvasive and effective imaging tool to distinguish TRS from TRD and to demonstrate anatomic stability over time. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2024;55:244-248.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"244-248"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lindsey A Chew, Nikhil V Gadiraju, Anjali M Saini, S Tammy Hsu, Vahid Ownagh, Lejla Vajzovic
{"title":"Pediatric Eye Screening: Current Standards and Gaps in Care.","authors":"Lindsey A Chew, Nikhil V Gadiraju, Anjali M Saini, S Tammy Hsu, Vahid Ownagh, Lejla Vajzovic","doi":"10.3928/23258160-20241216-03","DOIUrl":"10.3928/23258160-20241216-03","url":null,"abstract":"<p><p>The nonmydriatic, noncontact, and rapid acquisition features of ultra-widefield fundus (UWF) imaging create an invaluable tool for pediatric retinal screening in primary care. This review assesses the landscape of pediatric eye screening, identifies gaps in diagnosing a range of pediatric retinal conditions, and discusses potential uses of UWF imaging for retinal screening. The standards for pediatric eye screening in primary care include red reflex testing, direct ophthalmoscopy, external ocular exam, instrument-based screening, and visual acuity testing. These tests fail to diagnose several treatable retinal diseases. In this gap, UWF retinal imaging provides a panoramic view of the retinal landscape, allowing for a more comprehensive examination. For several pediatric retinal conditions (eg, retinal detachment, retinopathy of prematurity, Coats' disease, familial exudative vitreoretinopathy, Stargardt disease, ocular toxocariasis), UWF retinal imaging provides the high spatial resolution necessary for reliable diagnosis, expediting time to treatment while maintaining low false positive rates. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:232-239.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"232-239"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth A Mellencamp, Dimitrios C Arhontoulis, Sydney C DiBona, David E Baxley, Nicolas A Yannuzzi, Peter H Tang
{"title":"Novel Gore-Tex Scleral Fixation Technique for Dual-Eyelet Intraocular Lenses.","authors":"Elizabeth A Mellencamp, Dimitrios C Arhontoulis, Sydney C DiBona, David E Baxley, Nicolas A Yannuzzi, Peter H Tang","doi":"10.3928/23258160-20241216-05","DOIUrl":"10.3928/23258160-20241216-05","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"202-204"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raziyeh Mahmoudzadeh, Mirataollah Salabati, Taku Wakabayashi, Dillan Patel, Sonia Mehta, Ajay E Kuriyan, M Ali Khan, Michael A Klufas, Sunir J Garg, Omesh P Gupta, Carl D Regillo, Yoshihiro Yonekawa, Michael N Cohen, Shreya Swaminathan
{"title":"Reply: \"Integrity\" Assessment Following Rhegmatogenous Retinal Detachment Repair.","authors":"Raziyeh Mahmoudzadeh, Mirataollah Salabati, Taku Wakabayashi, Dillan Patel, Sonia Mehta, Ajay E Kuriyan, M Ali Khan, Michael A Klufas, Sunir J Garg, Omesh P Gupta, Carl D Regillo, Yoshihiro Yonekawa, Michael N Cohen, Shreya Swaminathan","doi":"10.3928/23258160-20241207-01","DOIUrl":"10.3928/23258160-20241207-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"251-252"},"PeriodicalIF":0.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashish Sharma, Lihteh Wu, Steven Bloom, Paulo Stanga, David A Eichenbaum, Arshad M Khanani, Lorenzo Iuliano, Daniele Veritti, Valentina Sarao, Paolo Lanzetta, Anjana Mirajkar, Manish Nagpal, Kevin F Elwood, Mathew W MacCumber, Kourous A Rezaei
{"title":"RWC Update: Intraocular Inflammation and Retinal Pharmacotherapy; Giant Retinal Tear; ILM Peeling in Myopic Macular Schisis.","authors":"Ashish Sharma, Lihteh Wu, Steven Bloom, Paulo Stanga, David A Eichenbaum, Arshad M Khanani, Lorenzo Iuliano, Daniele Veritti, Valentina Sarao, Paolo Lanzetta, Anjana Mirajkar, Manish Nagpal, Kevin F Elwood, Mathew W MacCumber, Kourous A Rezaei","doi":"10.3928/23258160-20250220-01","DOIUrl":"https://doi.org/10.3928/23258160-20250220-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":"56 3","pages":"133-135"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reut Shor, Marko Popovic, Andrew Mihalache, Rajeev H Muni
{"title":"A Cross-Sectional Survey of Optometrists in Canada Regarding Referral Patterns and a Needs Assessment for an Artificial Intelligence Referral Screening Tool for Epiretinal Membrane.","authors":"Reut Shor, Marko Popovic, Andrew Mihalache, Rajeev H Muni","doi":"10.3928/23258160-20241217-01","DOIUrl":"10.3928/23258160-20241217-01","url":null,"abstract":"<p><strong>Background and objective: </strong>This study evaluated optometrists' referral patterns for epiretinal membrane (ERM) patients in Ontario, Canada, and their attitudes towards an artificial intelligence (AI) tool for improving referral accuracy. An anonymous online survey with 11 questions was conducted.</p><p><strong>Patients and methods: </strong>The survey targeted optometrists across Ontario, Canada. The survey aimed to understand optometrists' reasons for referring ERM patients to retina specialists, their expectations of the specialists' management, and their openness to using an AI tool for triage. To prevent bias, the survey described an AI tool as an online consultation feature limited to predefined questions without directly mentioning \"AI.\" The main objective was to assess if this AI tool could decrease unnecessary ERM referrals to retina specialists.</p><p><strong>Results: </strong>A total of 135 optometrists participated. They reported seeing an average of eight ERM cases monthly, referring every fourth case to a specialist. The primary referral reason (84.3%) was to evaluate for surgery. In terms of referral confidence, 34.3% felt fully confident (5/5), and 47.8% slightly less so (4/5). They anticipated that 20% of patients would have a change in management post-consultation with a specialist. When introduced to the concept of an online consultation tool for patient screening, optometrists believed it could reduce their ERM referrals by 40%.</p><p><strong>Conclusions: </strong>Optometrists often refer ERM patients to retina specialists. An AI tool for screening ERM referrals, based on presenting vision and OCT images, could significantly lower the number of unnecessary referrals, offering clinical guidance to optometrists. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:166-169.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"166-169"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Balas, Mariam Issa, Marko M Popovic, Chris Zajner, Lana Moayad, Paola Oquendo Aponte, Hesham Hamli, Peng Yan, Tom Wright, Isabela M Melo, Rajeev H Muni
{"title":"Correlation Between Photoreceptor and Vascular Parameters in Diabetic Retinopathy Using Adaptive Optics.","authors":"Michael Balas, Mariam Issa, Marko M Popovic, Chris Zajner, Lana Moayad, Paola Oquendo Aponte, Hesham Hamli, Peng Yan, Tom Wright, Isabela M Melo, Rajeev H Muni","doi":"10.3928/23258160-20241015-03","DOIUrl":"10.3928/23258160-20241015-03","url":null,"abstract":"<p><strong>Background and objective: </strong>This study aimed to investigate correlations between photoreceptor and vascular parameters in varying stages of diabetic retinopathy (DR) using adaptive optics (AO) imaging.</p><p><strong>Patients and methods: </strong>In this single-center, prospective cohort study, 29 participants (46 eyes) were classified into control/mild non-proliferative DR (NPDR), moderate/severe NPDR, and proliferative DR. AO images of photoreceptors and retinal vasculature were analyzed, and Spearman's correlation (ρ) was used to assess relationships between photoreceptor density and vascular parameters.</p><p><strong>Results: </strong>Higher cone density was inversely associated with total vessel (ρ = 0.22, <i>P</i> = 0.03) and lumen diameters (ρ = -0.24, <i>P</i> = 0.01), while higher dispersion was associated with total vessel (ρ = 0.19, <i>P</i> = 0.06) and lumen diameters (ρ = 0.21, <i>P</i> = 0.04). These associations were primarily significant in mild NPDR. No significant correlations were found in advanced DR stages.</p><p><strong>Conclusion: </strong>This study underscores intricate neurovascular correlations in early-stage DR, suggesting these parameters may aid in early disease detection. Further research is needed to understand whether similar correlations exist in advanced DR. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2025;56:150-158.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"150-158"},"PeriodicalIF":0.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}