Ophthalmic surgery, lasers & imaging retina最新文献_第4页

Ultra-widefield Swept-source Optical Coherence Tomography Angiography in Adults With a History of Retinopathy of Prematurity. 有早产儿视网膜病变史的成人的超宽视场扫描源光学相干断层血管造影。

IF 1.1 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-08-21 DOI: 10.3928/23258160-20250723-01

Ioanna Ploumi, Xinyi Ding, Ying Zhu, Celine Chaaya, Chong Chen, Kayla N Nodecker, Shivesh H Shah, Sandra Hoyek, Selin S Gumustop, Sarah L Wagner, Nimesh A Patel, John B Miller

引用次数: 0

Bilateral Endogenous Nocardia Endophthalmitis: A Case Report. 双侧内源性诺卡菌眼内炎1例。

IF 1.1 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-08-21 DOI: 10.3928/23258160-20250721-01

Nish Patel, Calvin C Robbins, Evgeny Gelman, Uday R Desai

引用次数: 0

Coats-like Retinopathy Associated With 18p Deletion Syndrome. 涂层样视网膜病变与18p缺失综合征相关。

IF 1.1 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-08-11 DOI: 10.3928/23258160-20250718-02

Jeremia E Williams, Franco M Recchia

引用次数: 0

Clinical Outcomes of Pars Plana Vitrectomy for Persistent Vitreous Opacities in Infectious and Noninfectious Uveitis. 感染性和非感染性葡萄膜炎持续性玻璃体混浊的玻璃体切除术的临床效果。

IF 1.1 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-08-11 DOI: 10.3928/23258160-20250718-01

Ludovico Alisi, Marta Armentano, Giacomo Visioli, Massimo Accorinti, Elvia Mastrogiuseppe, Mattia D'Andrea, Giulia Firmani, Maria Pia Pirraglia, Magda Gharbiya, Ludovico Iannetti

{"title":"Clinical Outcomes of Pars Plana Vitrectomy for Persistent Vitreous Opacities in Infectious and Noninfectious Uveitis.","authors":"Ludovico Alisi, Marta Armentano, Giacomo Visioli, Massimo Accorinti, Elvia Mastrogiuseppe, Mattia D'Andrea, Giulia Firmani, Maria Pia Pirraglia, Magda Gharbiya, Ludovico Iannetti","doi":"10.3928/23258160-20250718-01","DOIUrl":"https://doi.org/10.3928/23258160-20250718-01","url":null,"abstract":"Background and objective: This study evaluated functional and inflammatory outcomes after pars plana vitrectomy (PPV) in patients with persistent vitreous opacities due to infectious and noninfectious uveitis unresponsive to medical therapy.Patients and methods: Twenty-three eyes with noninfectious uveitis and 16 eyes with infectious uveitis were enrolled. Functional and inflammatory parameters were assessed, focusing on best-corrected visual acuity (BCVA), vitreous haze, and inflammation.Results: At 6 months, both vitreous haze and anterior chamber inflammation decreased from severe to minimal levels. BCVA improved in 28 eyes (71.8%), remained stable in five eyes (12.8%), and worsened in six eyes (15.4%). Linear regression analysis showed that preoperative BCVA significantly predicted visual improvement (coefficient = 0.60, 95% confidence interval [CI]: 0.22-0.98, P = 0.003), while etiology (P = 0.217) and lens status (P = 0.201) were not significant factors (R2 = 0.34). Elevated intraocular pressure occurred in five patients, with two requiring trabeculectomy after 3 months. In two cases, epiretinal membrane formation progressed to tractional retinal detachment within 6 months.Conclusion: PPV is an effective treatment for persistent vitreous opacities, resulting in visual improvement and stabilization of inflammation. Postoperative follow-up is necessary due to potential complications and recurrence.","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-8"},"PeriodicalIF":1.1,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144822157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonsyndromic Retinitis Pigmentosa With Pathogenic CEP290 Mutations. 非综合征性视网膜色素变性伴致病性CEP290突变。

IF 1.1 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-08-01 Epub Date: 2025-05-23 DOI: 10.3928/23258160-20250513-01

Bijal A Kikani, Jordan A Ueberroth, Cory A Christensen, Mark P Breazzano

{"title":"Nonsyndromic Retinitis Pigmentosa With Pathogenic CEP290 Mutations.","authors":"Bijal A Kikani, Jordan A Ueberroth, Cory A Christensen, Mark P Breazzano","doi":"10.3928/23258160-20250513-01","DOIUrl":"10.3928/23258160-20250513-01","url":null,"abstract":"CEP290 variants, commonly associated with Leber congenital amaurosis, cause severe visual impairment within the first year of life. Herein, we report a unique case of nonsyndromic retinitis pigmentosa with foveal sparing and preserved central vision in a patient harboring two pathogenic CEP290 variants. A 28-year-old woman presented with longstanding poor peripheral vision and nyctalopia since childhood, but with visual acuity of 20/25 bilaterally. Examination showed retinal arteriolar attenuation, diffuse foveal-sparing retinal atrophy, and peripheral bone spicule pigmentation. Genetic testing identified two pathogenic nonsense mutations in CEP290 (c.1666del and c.4057G>T) and heterozygous missense mutations in BBS5 (c.715A>G), PDE6A (c.367G>T), and RPGR (c.2594_2596del), which were variants of unknown significance. Although nonsense mutations in CEP290 are associated with severe and early-onset vision loss, our patient demonstrated a mild retinitis pigmentosa phenotype with stable disease over 6 months. This case expands the phenotypic spectrum of CEP290-associated diseases and suggests a potential role for genetic modifiers in disease severity.","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"506-509"},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chlorhexidine Versus Povidone Iodide for Intravitreal Injection Antisepsis. 氯己定与碘化聚维酮在玻璃体内注射消毒中的比较。

IF 1.1 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-08-01 Epub Date: 2025-07-16 DOI: 10.3928/23258160-20250604-03

Grace S Fine, Seenu M Hariprasad, Jonathan L Prenner

引用次数: 0

Silicone Oil Into the Suprachoroidal Space: An Illustrative Report and Literature Review. 硅油进入脉络膜上腔：一个说明性报告和文献综述。

IF 1.1 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-08-01 Epub Date: 2025-06-18 DOI: 10.3928/23258160-20250522-02

Gabriel Castilho S Barbosa, Nathália Nishiyama Tondelli, Cleide Guimarães Machado, André Vieira Gomes

{"title":"Silicone Oil Into the Suprachoroidal Space: An Illustrative Report and Literature Review.","authors":"Gabriel Castilho S Barbosa, Nathália Nishiyama Tondelli, Cleide Guimarães Machado, André Vieira Gomes","doi":"10.3928/23258160-20250522-02","DOIUrl":"10.3928/23258160-20250522-02","url":null,"abstract":"Silicone oil (SO) tamponade has been widely used in vitreoretinal surgery for complex retinal detachment cases, yet its migration into unintended intraocular spaces remains an uncommon but clinically significant complication. While sub-retinal and anterior chamber migration have been more frequently described, suprachoroidal SO migration is a rare event, with few reports in the literature. The underlying mechanisms proposed for this complication include transient hypotony, infusion cannula malposition, and structural vulnerabilities within the suprachoroidal space. This review synthesizes reported cases of suprachoroidal SO migration, detailing clinical presentations, surgical management approaches, and postoperative outcomes. Various drainage techniques have been attempted, including transscleral evacuation through posterior sclerotomies, internal drainage into the vitreous cavity via pars plana incisions, and adjunctive perfluorocarbon liquid injection to facilitate oil displacement. While some cases have been managed conservatively without surgical intervention, the long-term implications of retained SO in the suprachoroidal space remain largely unknown. Given its potential association with ciliary detachment, hypotony, and visual disturbances, careful patient monitoring is warranted. The current literature lacks comprehensive studies on the biological behavior of SO within the suprachoroidal compartment, and further investigations are necessary to assess its stability, potential toxic effects, and indications for surgical removal. This review aims to provide vitreoretinal surgeons with a systematic understanding of suprachoroidal SO migration, offering insights into pathophysiology, prevention strategies, and optimal surgical management based on current evidence.","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"495-500"},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early Outcomes After Initiation of Faricimab for Neovascular Age-Related Macular Degeneration. 法利西单抗治疗新生血管性年龄相关性黄斑变性的早期结果。

IF 1.1 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-08-01 Epub Date: 2025-05-15 DOI: 10.3928/23258160-20250304-02

Ferhina S Ali, David C Tabano, Durga S Borkar, Theodore Leng, Vincent Garmo, Ayesha Ahmed, Rachel Myers, Jacqueline K Shaia, Giulio Barteselli, Rishi P Singh

{"title":"Early Outcomes After Initiation of Faricimab for Neovascular Age-Related Macular Degeneration.","authors":"Ferhina S Ali, David C Tabano, Durga S Borkar, Theodore Leng, Vincent Garmo, Ayesha Ahmed, Rachel Myers, Jacqueline K Shaia, Giulio Barteselli, Rishi P Singh","doi":"10.3928/23258160-20250304-02","DOIUrl":"10.3928/23258160-20250304-02","url":null,"abstract":"Background and objective: This study assessed treatment patterns and early outcomes among patients with neovascular age-related macular degeneration (nAMD) initiating faricimab in routine clinical practice in the United States.Patients and methods: FARETINA-AMD is a retrospective study among patients with nAMD initiating faricimab from February 2022 to June 2023 identified from the US IRIS® Registry.Results: Included were 21,508 patients previously treated with anti-vascular endothelial growth factor (anti-VEGF) (25,784 eyes) and 1,836 treatment-naïve patients (1,982 eyes) with nAMD. Among previously treated eyes, visual acuity remained stable with faricimab. In treatment-naïve eyes, mean ± SD visual acuity improved from 56.7 ± 24.1 letters at index to 61.4 ± 22.3 after faricimab injection 4 (P < 0.01). Mean ± SD central subfield thickness improved from 315.2 ± 80.0 (index) to 264.9 ± 60.1 μm (injection 4) in treatment-naïve eyes and 296.2 ± 95.5 to 273.0 ± 81.4 μm in previously treated eyes (both P < 0.01).Conclusions: Among patients with nAMD receiving faricimab, visual acuity improved in treatment-naïve eyes, and both previously treated and treatment-naïve eyes experienced anatomical improvement.","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"468-477"},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Vasoproliferative Tumor in a Patient With Coats' Disease: Multiple Therapeutic Approach in Current Era. 科茨病患者血管增生性肿瘤的治疗：当代的多种治疗方法

IF 1.1 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-08-01 Epub Date: 2025-06-18 DOI: 10.3928/23258160-20250522-01

Leonardo Bottazzi, Gaia L'Abbate, Claudia Fossataro, Maria Cristina Savastano, Riccardo Sacconi, Stanislao Rizzo, Francesco Bandello, Giuseppe Querques

引用次数: 0

Early Outcomes After Initiation of Faricimab in Patients With Diabetic Macular Edema. 法利昔单抗治疗糖尿病性黄斑水肿的早期疗效。

IF 1.1 4区医学

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-08-01 Epub Date: 2025-05-15 DOI: 10.3928/23258160-20250304-01

Durga S Borkar, David C Tabano, Ferhina S Ali, Theodore Leng, Vincent Garmo, Ayesha Ahmed, Rachel Myers, Jacqueline K Shaia, Giulio Barteselli, Rishi P Singh

{"title":"Early Outcomes After Initiation of Faricimab in Patients With Diabetic Macular Edema.","authors":"Durga S Borkar, David C Tabano, Ferhina S Ali, Theodore Leng, Vincent Garmo, Ayesha Ahmed, Rachel Myers, Jacqueline K Shaia, Giulio Barteselli, Rishi P Singh","doi":"10.3928/23258160-20250304-01","DOIUrl":"10.3928/23258160-20250304-01","url":null,"abstract":"Background and objective: This study evaluated treatment patterns and outcomes among patients with diabetic macular edema (DME) treated with the bispecific antibody faricimab in routine clinical practice in the United States.Patients and methods: FARETINA-DME was a retrospective study among patients with DME initiating faricimab from February 2022 to June 2023 identified from the United States IRIS® Registry.Results: Four thousand five hundred fourteen (4,514) patients (6,204 eyes) previously treated with anti-vascular endothelial growth factor (anti-VEGF) therapy and 691 treatment-naïve patients (851 eyes) were included. In previously treated eyes, mean ± SD visual acuity was 64.0 ± 18.3 letters at index and 65.3 ± 19.0 at faricimab injection 4. In treatment-naïve eyes, visual acuity improved from 60.3 ± 19.8 to 63.9 ± 18.5 letters (P < 0.01). Mean ± SD central subfield thickness improved from 364.3 ± 132.2 to 330.1 ± 121.2 μm in previously treated eyes and 359.6 ± 115.0 to 307.4 ± 114.6 μm in treatment-naïve eyes (both P < 0.01).Conclusions: In patients with DME receiving faricimab, visual acuity was maintained in previously treated and improved in treatment-naïve eyes. Both groups had anatomical improvement.","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"478-486"},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144079390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0