Bertan Cakir, Bryan L Peacker, Rebecca Zeng, Jack H Tracy, Yilin Feng, John B Miller
{"title":"Extensive Endolaser During Vitrectomy for Primary Rhegmatogenous Retinal Detachment Is Associated With Epiretinal Membrane Formation.","authors":"Bertan Cakir, Bryan L Peacker, Rebecca Zeng, Jack H Tracy, Yilin Feng, John B Miller","doi":"10.3928/23258160-20240131-02","DOIUrl":"10.3928/23258160-20240131-02","url":null,"abstract":"<p><strong>Background and objective: </strong>Epiretinal membrane (ERM) formation, a common complication following pars plana vitrectomy (PPV) for primary rhegmatogenous retinal detachment (RRD) repair, is associated with vision loss and metamorphopsias. Although laser retinopexy is generally associated with ERM formation, the correlation between the extent of laser treatment and ERM formation during PPV is not well established. The aim of this study was to identify risk factors associated with ERM formation including extend of endolaser retinopexy after PPV for primary RRD.</p><p><strong>Patients and methods: </strong>A retrospective, observational case series of 181 consecutive patients (185 eyes) who underwent PPV for primary RRD repair by a single surgeon was performed. Charts were reviewed by two independent reviewers, and de-identified data including patient characteristics and intraoperative findings such as number of laser spots placed were recorded.</p><p><strong>Results: </strong>Postoperative ERM formation occurred in 75 eyes (40.5%) of which 68 (90.6%) were Stage 1, two (2.6%) were Stage 2, three (4%) were Stage 3, and two (2.6%) were Stage 4. Only one patient required secondary PPV for visually significant ERM. Patients with ERM had significantly more laser spots compared with patients with no ERM, with a mean of 807 and 519 laser spots respectively (95% CI: 387.6 to -187.3; <i>P</i> < 0.0001). Univariable analysis identified ≥750 endolaser spots (odds ratio [OR] = 4.0, 95% CI: 2.0 to 8.4; <i>P</i> < 0.0001), ≥4 retinal tears (OR = 2.8, 95%: CI 1.4 to 6.4; <i>P</i> = 0.005), and female sex (OR = 2.0, 95% CI: 1.1 to 3.7; <i>P</i> = 0.02) as significantly associated factors. After adjusting for potential confounding factors (ie, age, sex, macula status, lattice degeneration, length of symptoms, vitreous hemorrhage, number of endolaser spots, number of retinal tears) in multivariable logistic regression, ≥ 750 endolaser spots (OR = 2.4; <i>P</i> = 0.04) and female sex (OR = 2.4; <i>P</i> = 0.03) persisted as significant independent factors.</p><p><strong>Conclusions: </strong>Our study identified ≥ 750 laser spots and female sex as independent risk factors for ERM formation following PPV for RRD with an OR of 2.4 each. Although the incidence of ERM formation was generally high (40.5%), only one case required secondary PPV with ERM peeling, and visual outcomes were comparable between patients with and without ERM at final follow up. While endolaser photocoagulation is critical for successful RRD repair, consideration of the risk of ERM formation with extensive laser exposure is warranted. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2024;55:326-333.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"326-333"},"PeriodicalIF":0.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisco Javier Valentín Bravo, Laura Broc Iturralde, Laura Pulido Sánchez-Carnerero, Rachid Bouchikh El Jarroudi, Xavier Valldeperas
{"title":"Multimodal Imaging to Detect Silicone Oil Emulsification and Its Related Complications.","authors":"Francisco Javier Valentín Bravo, Laura Broc Iturralde, Laura Pulido Sánchez-Carnerero, Rachid Bouchikh El Jarroudi, Xavier Valldeperas","doi":"10.3928/23258160-20240213-01","DOIUrl":"10.3928/23258160-20240213-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"358"},"PeriodicalIF":1.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139972893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nystagmus and Foveal Hypoplasia in a Carrier of Oculocutaneous Albinism.","authors":"Neha Arora, Sandra Hoyek, Nimesh A Patel","doi":"10.3928/23258160-20240207-03","DOIUrl":"10.3928/23258160-20240207-03","url":null,"abstract":"<p><p>We report a 23-year-old female patient with ophthalmic features of albinism, including refractive errors, nystagmus, depigmented fundus, and foveal hypoplasia. She presented for a rhegmatogenous retinal detachment, which was surgically reattached with no complications. Further genetic testing revealed the presence of a heterozygous pathogenic oculocutaneous albinism OCA2 gene mutation, conferring carrier status. To the best of our knowledge, this is the first reported case of typical ocular phenotype of albinism, specifically nystagmus, in a patient who is carrier for oculo-cutaneous albinism. Further research is required to expand the genotype-phenotype relationship in carriers of oculocutaneous albinism. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2024;55:349-353.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":"55 6","pages":"349-353"},"PeriodicalIF":0.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashish Sharma, Lihteh Wu, Steven Bloom, Paulo Stanga, Nassim Abreu, David Eichenbaum, Carl Regillo, Robyn Guymer, Kanwaljeet Harjot Madan, Kourous A Rezaei
{"title":"RWC Update: Removal of Subretinal Band Without Retinotomy; Geographic Atrophy: How Do You Select Appropriate Patients for Anti-Complement Therapy?; Shaken Baby Syndrome.","authors":"Ashish Sharma, Lihteh Wu, Steven Bloom, Paulo Stanga, Nassim Abreu, David Eichenbaum, Carl Regillo, Robyn Guymer, Kanwaljeet Harjot Madan, Kourous A Rezaei","doi":"10.3928/23258160-20240523-01","DOIUrl":"10.3928/23258160-20240523-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":"55 6","pages":"305-308"},"PeriodicalIF":0.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141301195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachel Tandias, Itika Garg, Margaret J Duich, Filippos Vingopoulos, Raviv Katz, Rebecca Zeng, Leo A Kim, Deeba Husain, Dean Eliott, Nimesh A Patel, John B Miller, Rachel Tandias, Itika Garg
{"title":"Assessment of Microvascular Changes After Rhegmatogenous Retinal Detachment Repair Using Wide-Field Swept-Source Optical Coherence Tomography Angiography.","authors":"Rachel Tandias, Itika Garg, Margaret J Duich, Filippos Vingopoulos, Raviv Katz, Rebecca Zeng, Leo A Kim, Deeba Husain, Dean Eliott, Nimesh A Patel, John B Miller, Rachel Tandias, Itika Garg","doi":"10.3928/23258160-20240130-01","DOIUrl":"10.3928/23258160-20240130-01","url":null,"abstract":"<p><strong>Background and objective: </strong>Our objective was to evaluate retinal microvascular changes and visual outcomes following rhegmatogenous retinal detachment (RRD) repair using wide-field swept-source optical coherence tomography angiography (WF SS-OCTA).</p><p><strong>Patients and methods: </strong>The study included 116 eyes of 111 patients with macula-off (<i>n</i> = 68) or macula-on (<i>n</i> = 48) RRD treated with a single successful procedure, 79 fellow eyes, and 183 eyes of control patients imaged with WF SS-OCTA (3 ×3, 6 ×6, and 12 ×12 mm images). Mixed-effects multiple linear regression models were used for statistical analysis.</p><p><strong>Results: </strong>Vessel density (VD) and vessel skeletonized density (VSD) of the superficial capillary plexus (3 ×3 mm scans) and full-thickness retina (12 ×12 mm) were significantly reduced in RRD eyes compared to fellow and control eyes. Decreased VSD and VD in all layers (3 ×3 mm and 6 ×6 mm) were significantly associated with greater preoperative extent of retinal detachment (<i>P</i> < 0.05) and poorer postoperative best-corrected visual acuity (BCVA) in RRD eyes (<i>P</i> < 0.05). Macula-off status was associated with increased foveal avascular zone irregularity (12 ×12 mm, <i>P</i> = 0.02).</p><p><strong>Conclusions: </strong>Decreased VD on WF SS-OCTA is associated with poorer postoperative BCVA following RRD repair. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2024;55:310-317.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"310-317"},"PeriodicalIF":1.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retinal Nerve Fiber Layer Changes in Patients With Chronic Obstructive Pulmonary Disease Compared to Healthy Controls: A Meta-analysis.","authors":"Dimitrios Kazantzis, Genovefa Machairoudia, Stylianos Kandarakis, George Theodossiadis, Panagiotis Theodossiadis, Irini Chatziralli","doi":"10.3928/23258160-20240220-01","DOIUrl":"10.3928/23258160-20240220-01","url":null,"abstract":"<p><strong>Background and objective: </strong>This study investigated changes in retinal nerve fiber layers (RNFL) in patients diagnosed with chronic obstructive pulmonary disease (COPD) compared to healthy control patients, using optical coherence tomography.</p><p><strong>Methods: </strong>PubMed, Cochrane Library, and Google Scholar databases were systematically searched for published articles comparing RNFL between patients with COPD and healthy controls. Standardized mean difference (SMD) with 95% confidence interval (CI) was computed to compare continuous variables.</p><p><strong>Results: </strong>Average RNFL thickness was significantly reduced in COPD patients compared to healthy controls (SMD = -0.31, 95% CI = -0.48 to -0.14, <i>P</i> = 0.0004, I<sup>2</sup> = 0%). Average RNFL thickness did not differ significantly between patients with mild/moderate COPD and healthy controls (SMD = -0.17, 95% CI = -0.39 to 0.04, <i>P</i> = 0.12, I<sup>2</sup> = 2%), while a statistically significant reduction in average RNFL thickness was noticed in patients with severe COPD compared to healthy controls (SMD = -0.72, 95% CI = -1.23 to -0.21, <i>P</i> = 0.006, I<sup>2</sup> = 83%). Average RNFL thickness was significantly higher in patients with mild/moderate COPD compared to patients with severe COPD (S<i>MD</i> = 0.69, 95% CI = 0.29 to 1.09, <i>P</i> = 0.0008, I<sup>2</sup> = 66%).</p><p><strong>Conclusions: </strong>This meta-analysis showed that RNFL thickness was decreased in patients with COPD compared to healthy controls. Patients diagnosed with severe COPD seem to be more affected and have thinner RNFL. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2024;55:334-342.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"334-342"},"PeriodicalIF":0.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140294209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashish Sharma, Lihteh Wu, Steven Bloom, Paulo Stanga, Jaydeep Walinjkar, Shree Ramkrishna Netralaya, Afroz Q Patel, Raghunath Netralaya, Luke Nicholson, Paolo Lanzetta, Daniele Veritti, Valentina Sarao, David Boyer, Chui Ming Gemmy Cheung, Ayushi Gupta, Vishal Agrawal, Kourous A Rezaei
{"title":"RWC Update: Different Surgical Techniques for Macular Hole Associated With Retinal Detachment; Diabetic Macular Edema - How Do You Treat Patients With Good Visual Acuity?; Benign Familial Fleck Retina.","authors":"Ashish Sharma, Lihteh Wu, Steven Bloom, Paulo Stanga, Jaydeep Walinjkar, Shree Ramkrishna Netralaya, Afroz Q Patel, Raghunath Netralaya, Luke Nicholson, Paolo Lanzetta, Daniele Veritti, Valentina Sarao, David Boyer, Chui Ming Gemmy Cheung, Ayushi Gupta, Vishal Agrawal, Kourous A Rezaei","doi":"10.3928/23258160-20240425-01","DOIUrl":"10.3928/23258160-20240425-01","url":null,"abstract":"","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":"55 5","pages":"249-252"},"PeriodicalIF":1.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140944731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retinal Detachment After Macular Hole Repair in Alport Syndrome.","authors":"Brian Chhoy, Karen M Wai, Theodore Leng","doi":"10.3928/23258160-20240208-01","DOIUrl":"10.3928/23258160-20240208-01","url":null,"abstract":"<p><p>Alport syndrome is characterized by type IV collagen network disruptions leading to renal, auditory, and ocular manifestations. This case report details a 24-year-old man with Alport syndrome who developed a rhegmatogenous retinal detachment following macular hole repair. The patient underwent a successful vitrectomy and internal limiting membrane peel for macular hole repair but returned with vision loss due to retinal detachment five weeks later, which necessitated a combined scleral buckle and vitrectomy. This is the first case describing rhegmatogenous retinal detachment post-macular hole repair in Alport syndrome. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2024;55:289-292.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"289-292"},"PeriodicalIF":0.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139972894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lauren Kiryakoza, Natasha Ferreira Santos da Cruz, Sandra Hoyek, Audina M Berrocal
{"title":"Retinopathy With Variant of Unknown Significance and Atypical Chorioretinal Coloboma in the Setting of Prematurity.","authors":"Lauren Kiryakoza, Natasha Ferreira Santos da Cruz, Sandra Hoyek, Audina M Berrocal","doi":"10.3928/23258160-20240202-01","DOIUrl":"10.3928/23258160-20240202-01","url":null,"abstract":"<p><p>A 37-week-old girl underwent ophthalmic examination. Born at 32 weeks, the infant weighed 680 grams and received high-flow nasal cannula for respiratory distress of the newborn. Dilated fundus examination of the right eye revealed an atypical chorioretinal coloboma; the left eye revealed hyperpigmentary changes in the macula. Fluorescein angiography of both eyes showed retinal vascularization to zone II. Genetic testing revealed a heterozygous variant of uncertain significance in the catenin Alpha 1 (CTNNA1) gene. CTNNA1 gene abnormalities have been implicated as causes of familial exudative vitreoretinopathy (FEVR). It is important to recognize possible simultaneous retinopathy of prematurity and FEVR. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2024;55:285-288.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"285-288"},"PeriodicalIF":0.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139972895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prasida Unni, Jonathan Tijerina, Sandra Hoyek, Caroline Cotton, Humberto Salazar, Kenneth C Fan, Nimesh A Patel
{"title":"In-Office Lens Repositioning for Anterior Crystalline Lens Dislocation.","authors":"Prasida Unni, Jonathan Tijerina, Sandra Hoyek, Caroline Cotton, Humberto Salazar, Kenneth C Fan, Nimesh A Patel","doi":"10.3928/23258160-20240116-01","DOIUrl":"10.3928/23258160-20240116-01","url":null,"abstract":"<p><strong>Background and objective: </strong>We describe an in-office lens repositioning technique for anterior crystalline lens dislocation.</p><p><strong>Patients and methods: </strong>We present a case series of four patients with spontaneous or traumatic anterior crystalline lens dislocation.</p><p><strong>Results: </strong>The technique included supine patient positioning, gentle pressure with a cotton swab on the peripheral cornea to guide the lens into the posterior chamber, and the use of a miotic agent afterward to prevent subsequent subluxation. In the four cases described, the in-office technique successfully restored the lens to the posterior chamber, improved vision, and decreased intraocular pressure in most instances by resolving the angle closure secondary to pupillary block.</p><p><strong>Conclusions: </strong>The in-office lens repositioning technique is appropriate as an acute non-surgical intervention or temporizing measure for anterior crystalline lens dislocation. <b>[<i>Ophthalmic Surg Lasers Imaging Retina</i> 2024;55:293-298.]</b>.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"293-298"},"PeriodicalIF":0.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139546730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}