Comparison of Multiple Techniques for Measuring Geographic Atrophy: A Systematic Review and Network Meta-Analysis.

IF 0.9 4区医学 Q4 OPHTHALMOLOGY

Ophthalmic surgery, lasers & imaging retina Pub Date : 2025-03-01 DOI:10.3928/23258160-20250214-03

Tiago N O Rassi, William W Binotti, Eduardo Mund Carreirao Danielli, Sacha Pereira Fernandes, Daniela Cristina Schroff Machado, Dillan Cunha Amaral, Eduardo A Novais, Ricardo Noguera Louzada, Fernando Marcondes Penha, Mauricio Maia, Jay S Duker

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引用次数: 0

Abstract

This study compared techniques for measuring geographic atrophy (GA) against the standard autofluorescence blue (AF-Blue). The design was a Bayesian network meta-analysis. PubMed, Scopus, and Cochrane were searched for studies comparing GA imaging techniques. AF-Blue, autofluorescence green (AF-Green), autofluorescence infrared (AF-IR), near-infrared reflectance (NIR), multicolor autofluorescence AF (MC-AF), optical coherence tomography fundus image (OFI), en face sub-retinal pigment epithelium (SubRPE) slab, OCT angiography (OCTA), color fundus photography (CFP), and fluorescein angiography (FA) were included. A ratio of means (ROM) meta-analysis using a threshold based on an established minimally important difference was performed. (Pros-pero ID: CRD42023476459.) Included were 2,001 eyes from 18 studies and no significant differences among measurement techniques was found. The ROM showed that CFP, OCTA, SubRPE slab, OFI, and IR reflectance agreed well with AF-Blue. However, AF-Green, FA, and MC underestimated GA, and AF-IR overestimated it. It appears that there is a fair agreement between AF-Blue and current techniques for measuring GA. [Ophthalmic Surg Lasers Imaging Retina 2025;56:XX-XX.].

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来源期刊

Ophthalmic surgery, lasers & imaging retina OPHTHALMOLOGY-SURGERY

CiteScore

1.80

自引率

0.00%

发文量

期刊介绍： OSLI Retina focuses exclusively on retinal diseases, surgery and pharmacotherapy. OSLI Retina will offer an expedited submission to publication effort of peer-reviewed clinical science and case report articles. The front of the journal offers practical clinical and practice management features and columns specific to retina specialists. In sum, readers will find important peer-reviewed retina articles and the latest findings in techniques and science, as well as informative business and practice management features in one journal.