Ahmed Elghzali, Vinay Swami, M D Hossain, Garrett Jones, J Tyler Babek, Christian Hemmerich, Haley Howard, Seraphim Himes, Jennifer Cox, Alicia Ito Ford, Matt Vassar
{"title":"A Systematic Review and Meta-Analysis Assessing Diversity and Representation in Diabetic Retinopathy Clinical Trials in the U.S.","authors":"Ahmed Elghzali, Vinay Swami, M D Hossain, Garrett Jones, J Tyler Babek, Christian Hemmerich, Haley Howard, Seraphim Himes, Jennifer Cox, Alicia Ito Ford, Matt Vassar","doi":"10.1080/09286586.2025.2457620","DOIUrl":"https://doi.org/10.1080/09286586.2025.2457620","url":null,"abstract":"<p><strong>Purpose: </strong>To perform a systematic review and meta-analysis assessing the diversity and representation of diabetic retinopathy (DR) patients in clinical trials conducted in the United States from January 1, 2018, to December 31, 2023.</p><p><strong>Methods: </strong>A comprehensive search strategy was conducted on May 28th, 2024 using MEDLINE (PubMed) and Embase (Elsevier) to identify relevant clinical trials. Inclusion criteria included trials published between January 1, 2018 and December 31, 2023, focusing on interventions for DR that were conducted in the United States. Screening and data extraction were independently performed by three reviewers.</p><p><strong>Results: </strong>Eleven clinical trials met the inclusion criteria and were analyzed for participant representation based on sex, age, and race/ethnicity. Sex representation was rated as good in 9 of the 11 studies. However, age representation was rarely reported (only 1/11 studies) and race/ethnicity representation was poor in 6 of the 11 studies. The findings highlight significant underrepresentation of Asian and Black populations.</p><p><strong>Conclusion: </strong>This study reveals substantial disparities in the demographic representation within DR clinical trials in the United States, emphasizing the critical need for improved inclusion strategies. Enhancing diversity in these trials is essential for producing research findings that are more applicable to the broader population affected by DR, ultimately contributing to more equitable healthcare outcomes and advancing the effectiveness of treatments across diverse demographic groups.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"1-11"},"PeriodicalIF":1.7,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jia-Yan Kai, Xing-Xuan Dong, Yi-Fan Miao, Dan-Lin Li, Andrzej Grzybowski, Carla Lanca, Zeng-Liang Ruan, Chen-Wei Pan
{"title":"Impact of Ambient Air Pollution on Reduced Visual Acuity Among Children and Adolescents.","authors":"Jia-Yan Kai, Xing-Xuan Dong, Yi-Fan Miao, Dan-Lin Li, Andrzej Grzybowski, Carla Lanca, Zeng-Liang Ruan, Chen-Wei Pan","doi":"10.1080/09286586.2025.2457623","DOIUrl":"https://doi.org/10.1080/09286586.2025.2457623","url":null,"abstract":"<p><strong>Purpose: </strong>Previous studies have assessed the impact of air pollution on myopia from the individual level, while none of them have explored the role of air pollution in visual health disparities between different regions from the area level. This ecological study aimed to investigate the impact of ambient air pollution on reduced visual acuity (VA).</p><p><strong>Methods: </strong>The data were derived from the Chinese National Survey on Students' Constitution and Health (CNSSCH) conducted in 2014 and 2019, which involved 261,833 and 267,106 students respectively. The participants were 7-22 years old randomly selected from 30 mainland provinces in China. Locally weighted scatterplot smoothing (LOESS) regression models and fixed-effects panel regression models were used to explore the associations of provincial-level prevalence of reduced VA with air quality index (AQI), fine particulate matter ;(PM2.5), PM10, sulfur dioxide (SO2), carbon monoxide (CO), nitrogen dioxide (NO2) and ozone (O3) concentrations.</p><p><strong>Results: </strong>There were nearly linear positive dose-response relationships between AQI, air pollutant concentrations and the prevalence of reduced VA. After adjusting for covariates, an interquartile range increase in PM2.5 exposure was significantly associated with a 5.0% (95% confidence interval, 0.7%-9.3%) increase in the prevalence of reduced VA, whereas no significant associations were observed between AQI, the other five pollutants and the prevalence of reduced VA.</p><p><strong>Conclusion: </strong>Regions with more polluted air tend to have a higher prevalence of reduced VA. Exposure to PM2.5 might be an important risk factor for myopia among children and adolescents.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"1-8"},"PeriodicalIF":1.7,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2025-02-01Epub Date: 2024-03-07DOI: 10.1080/09286586.2024.2317816
Kwadwo Owusu Akuffo, Isaiah Osei Duah Junior, Eldrick Adu Acquah, Elna Abadua Mensah, Albert Kwadjo Amoah Andoh, David Ben Kumah, Bridget Senya Boateng, Josephine Ampomah Boateng, Kofi Osei-Poku, Werner Eisenbarth
{"title":"Low Vision Practice and Service Provision Among Optometrists in Ghana: A Nationwide Survey.","authors":"Kwadwo Owusu Akuffo, Isaiah Osei Duah Junior, Eldrick Adu Acquah, Elna Abadua Mensah, Albert Kwadjo Amoah Andoh, David Ben Kumah, Bridget Senya Boateng, Josephine Ampomah Boateng, Kofi Osei-Poku, Werner Eisenbarth","doi":"10.1080/09286586.2024.2317816","DOIUrl":"10.1080/09286586.2024.2317816","url":null,"abstract":"<p><strong>Purpose: </strong>To characterize practice patterns of low vision services among Optometrists in Ghana.</p><p><strong>Methods: </strong>The nationwide cross-sectional survey identified entities through the Ghana Optometrists Association (GOA) registry and utilized a semi-structured questionnaire to consolidate survey information that comprises practitioners' demographics, available services, diagnostic equipment, barriers to service provision and utilization, and interventions.</p><p><strong>Results: </strong>300 Optometrists were identified, with 213 surveyed (71% response rate). About fifty percent (52.6%) were in private practice, and more than two-thirds (77%) did not provide low vision services. Most (≥70%) reported lack of assistive devices, and basic eye care examination kits as the main barriers to low vision service provision. Similarly, practitioners reported unawareness of the presence of low vision centres (76.1%), and high cost of low vision aids (75.1%) as the prime perceived barriers for patients to utilize low vision services. Continuous professional development and public education (89-90%) were suggested as interventions to improve the uptake of low vision services. After statistical adjustment, private facility type (Adjusted odds ratio [AOR] = 0.35, <i>p</i> = 0.010) and lack of basic eye examination kits (AOR = 0.32, <i>p</i> = 0.002) were significantly associated with reduced odds of low vision service provision. Conversely, ≥15 years of work experience (AOR = 6.37, <i>p</i> = 0.011) was significantly associated with increased odds of low vision service provision.</p><p><strong>Conclusions: </strong>Overall, the results indicate inadequate low vision coverage and service delivery. Government policies must be directed towards equipping practitioners with equipment and subsidize patient cost of treatment to optimize low vision care.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"1-8"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140049993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2025-02-01Epub Date: 2024-03-20DOI: 10.1080/09286586.2024.2319243
Karissa M Wang, Anne L Coleman, Deyu Pan, Fei Yu, Victoria L Tseng
{"title":"Population-Level Associations Between Visual Impairment and Functional Difficulties in California.","authors":"Karissa M Wang, Anne L Coleman, Deyu Pan, Fei Yu, Victoria L Tseng","doi":"10.1080/09286586.2024.2319243","DOIUrl":"10.1080/09286586.2024.2319243","url":null,"abstract":"<p><strong>Purpose: </strong>The prevalence of visual impairment is increasing, and there is a need to understand the functional implications. Using the American Community Survey (ACS) data, this study examined the relationship between visual impairment and functional difficulties in California.</p><p><strong>Methods: </strong>Using the 2010-2014 and 2015-2019 ACS 5-year estimates from the U.S. Census, data were obtained for visual impairment and functional difficulties including hearing, cognitive, ambulatory, self-care, and independent living difficulties. The prevalence of vision impairment and each functional difficulty was calculated on the Medical Service Study Area (MSSA) level in California. Unadjusted and adjusted linear regression models were performed to estimate the association between visual impairment and each functional difficulty, adjusting for age, sex, race and ethnicity, education level, English-speaking ability, poverty status, health insurance status, and urbanity of residence location.</p><p><strong>Results: </strong>The prevalence of visual impairment in California was 2.3% (659,502 of 28,794,572) in 2010-2014 and 2.3% (709,353 of 30,231,767) in 2015-2019 among the population ≥ 18 years old. There were statistically significant associations between the prevalence of vision impairment and increased prevalence of all functional difficulties, with the most positive correlation observed with ambulatory difficulty (slope estimate 0.58 ± 0.072 for 2010-2014 and 0.78 ± 0.082 for 2015-2019 for ambulatory difficulty).</p><p><strong>Conclusions: </strong>There may be population-level impacts of functional consequences from vision impairment, suggesting the need for neighborhood-level investigation and policy-based interventions to address the burden of vision impairment on the population level.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"9-17"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140175815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2025-02-01Epub Date: 2024-03-20DOI: 10.1080/09286586.2024.2321902
Jung Hoo Lee, Seong Ho Kim, EunAh Kim
{"title":"Influence of Smoking and Controlled Medical Conditions on the Risks of Branch Retinal Vein Occlusion in South Korea: A Population-Based Study.","authors":"Jung Hoo Lee, Seong Ho Kim, EunAh Kim","doi":"10.1080/09286586.2024.2321902","DOIUrl":"10.1080/09286586.2024.2321902","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effect of controlled medical conditions and risk of lifetime smoking history on the prevalence of branch retinal vein occlusion (BRVO) based on the Korea National Health and Nutrition Survey (KNHANES) database from 2017-2021.</p><p><strong>Methods: </strong>The study population consisted of individuals aged ≥ 40 years who had completed ophthalmological questionnaires, underwent comprehensive ophthalmological examinations, and had at least one good-quality readable fundus photograph. Age, sex, hypertension status, diabetes status, dyslipidemia status, body mass index status, a history of chronic kidney disease (CKD), a lifetime smoking history of ≥ 100 cigarettes, and glaucoma were subjected to univariate and multivariate logistic regression analyses.</p><p><strong>Results: </strong>The estimated prevalence (± standard error) of RVO was 0.5% (±0.1%). Significant risk factors were one-year increase in age, female sex, hypertension (stage 1, controlled, uncontrolled, and undiagnosed hypertension), underweight, pre-obesity, history of CKD, lifetime smoking history of ≥ 100 cigarettes, and glaucoma. Controlled diabetes decreased the risk of BRVO by 55% (odds ratio [OR] = 0.45, 95% confidence interval [CI] = 0.22-0.89, <i>p</i> = 0.022) and controlled hyper-high-density-lipoprotein (HDL)-cholesterolemia decreased the risk by 69% (OR = 0.31, 95% CI = 0.13-0.76, <i>p</i> = 0.010).</p><p><strong>Conclusion: </strong>This study, for the first time, reported the association between lifetime smoking history of ≥ 100 cigarettes and BRVO in Korea. The risk of BRVO was lower in participants with controlled diabetes and hypo-HDL-cholesterolemia.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"44-51"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140175814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2025-02-01Epub Date: 2024-03-20DOI: 10.1080/09286586.2024.2321890
Anthea Burnett, Ngy Meng, Do Seiha, Neath Kong, Seila Chea, Malis Dean, Piseth Horm, Kim San Meas, Beatrice Varga, Suit May Ho, Myra McGuinness, Ling Lee
{"title":"Quality of Refractive Error Care in Cambodia: An Unannounced Standardized Patient Study.","authors":"Anthea Burnett, Ngy Meng, Do Seiha, Neath Kong, Seila Chea, Malis Dean, Piseth Horm, Kim San Meas, Beatrice Varga, Suit May Ho, Myra McGuinness, Ling Lee","doi":"10.1080/09286586.2024.2321890","DOIUrl":"10.1080/09286586.2024.2321890","url":null,"abstract":"<p><strong>Purpose: </strong>Quality-of-care in refractive error services is essential, as it directly affects vision outcomes, wellbeing, educational attainment, and workforce participation. In Cambodia, uncorrected refractive error is a leading cause of mild and moderate vision impairment in adults. We evaluated the quality of refractive error care in Cambodia by estimating the proportion of prescribed and dispensed spectacles appropriate for people's refractive error needs and factors associated with spectacle quality.</p><p><strong>Methods: </strong>A cross-sectional protocol was employed with 18 Khmer-speaking adult participants observing testing procedures in 156 optical services across six provinces in 2022. A total of 496 dispensed spectacles were assessed against spectacle quality indicators.</p><p><strong>Results: </strong>The analysis revealed that 35.1% of dispensed spectacles were of optimal quality. The most common error observed in sub-optimal spectacles was the presence of horizontal prism outside of tolerance limits. The study also found that 44.0% of emmetrope visits involved unnecessary prescription spectacle recommendations, and 18.3% of written prescriptions did not correspond with dispensed spectacles. Sex differences were observed, with men predominantly providing refractive error care and women more likely to be unnecessarily recommended prescription spectacles.</p><p><strong>Conclusion: </strong>The findings highlight the importance of prioritizing quality-of-care in refractive error services. A key recommendation is to consider regulatory mechanisms to ensure optical services employ appropriately qualified staff. Additionally, efforts should be made to eliminate unnecessary prescriptions -- especially for emmetropes and females -- standardize written prescriptions, ensure consistent pupil distance measurements, reduce reliance on autorefraction, and address the gender imbalance in the refractive error workforce.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"25-33"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140175817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2025-02-01Epub Date: 2024-05-06DOI: 10.1080/09286586.2024.2343714
Bijaya K Padhi, Parul Chawla Gupta, Nawal A Al Kaabi, Maha F Al-Subaie, Hayam A Alrasheed, Tarek Sulaiman, Ali A Rabaan, Mahalaqua Nazli Khatib, Shilpa Gaidhane, Quazi Syed Zahiruddin, Arkadiusz Dziedzic, Prakasini Satapathy, Najat J Fraj, Fatimah A Aldrazi, Neelima Kukreti, Sarvesh Rustagi, Hashem Abu Serhan
{"title":"Incidence and Association of Uveitis with COVID-19 Vaccination: A Systematic Review and Meta-Analysis.","authors":"Bijaya K Padhi, Parul Chawla Gupta, Nawal A Al Kaabi, Maha F Al-Subaie, Hayam A Alrasheed, Tarek Sulaiman, Ali A Rabaan, Mahalaqua Nazli Khatib, Shilpa Gaidhane, Quazi Syed Zahiruddin, Arkadiusz Dziedzic, Prakasini Satapathy, Najat J Fraj, Fatimah A Aldrazi, Neelima Kukreti, Sarvesh Rustagi, Hashem Abu Serhan","doi":"10.1080/09286586.2024.2343714","DOIUrl":"10.1080/09286586.2024.2343714","url":null,"abstract":"<p><strong>Purpose: </strong>In the wake of the COVID-19 pandemic, vaccines have been pivotal in curbing disease spread and severity. However, concerns over post-vaccination adverse events, including uveitis, an inflammatory ocular condition, have been noted. This systematic review and meta-analysis aimed to evaluate the incidence and association of uveitis following COVID-19 vaccination.</p><p><strong>Methods: </strong>A literature search was performed across several databases on October 21, 2023. Human studies examining the incidence of uveitis post-COVID-19 vaccination were included. The Newcastle-Ottawa Scale was used for quality appraisal of the included studies. Meta-analysis was performed to assess the overall incidence of uveitis and the relative risk of developing the condition post-vaccination. All statistical analyses were performed using R software version 4.3.</p><p><strong>Results: </strong>Six studies involving over 2 billion vaccine doses were included. The overall incidence of uveitis was 0.016% (95% CI: 0.010 to 0.026). No significant association was found between vaccination and the onset of uveitis (Relative Risk: 1.45 (95% CI: 0.82 to 2.57, <i>p</i> = 0.12) from four studies. The evidence quality was rated very low due to the limited number of studies and imprecision.</p><p><strong>Conclusion: </strong>This analysis indicates a low incidence of uveitis following COVID-19 vaccination and no significant association with the vaccine. The findings are constrained by the small number of studies and low certainty of evidence, underscoring the need for further research. Comprehensive and longitudinal studies are necessary to confirm these findings and reinforce public confidence in COVID-19 vaccination programs.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"112-120"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140866950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2025-02-01Epub Date: 2024-05-06DOI: 10.1080/09286586.2024.2338820
Germán Mejía-Salgado, Carlos Cifuentes-González, Doménico Barraquer-López, Juan Sebastián Pineda-Sierra, Camilo Andrés Rodríguez-Rodríguez, Paola Saboya-Galindo, Danna Lesley-Cruz, Alejandra de-la-Torre
{"title":"Colombian Ocular Diseases Epidemiology Study (CODES): Prevalence Incidence, and Sociodemographic Characterization of Vision Impairment (2015-2019), A Nationwide Study.","authors":"Germán Mejía-Salgado, Carlos Cifuentes-González, Doménico Barraquer-López, Juan Sebastián Pineda-Sierra, Camilo Andrés Rodríguez-Rodríguez, Paola Saboya-Galindo, Danna Lesley-Cruz, Alejandra de-la-Torre","doi":"10.1080/09286586.2024.2338820","DOIUrl":"10.1080/09286586.2024.2338820","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the prevalence, incidence, and sociodemographic characterization of moderate to severe vision impairment (MSVI) and blindness in Colombia based on the National Health Registry Integrated Social Protection Information System (SISPRO) Database.</p><p><strong>Methods: </strong>We performed a nationwide population-based study using SISPRO and the International Classification of Diseases. Total and new cases were identified to calculate the prevalence and incidence per 100,000 inhabitants of MSVI and blindness between 2015 and 2019. Blindness was defined as a best-corrected visual acuity (BCVA) of less than 20/400 in the better-seeing eye. Meanwhile, MSVI is a BCVA from 20/70 to equal or better than 20/400 in the better-seeing eye. An ANOVA test was performed to identify age differences. A conditional autoregressive model was also employed to depict standardized morbidity rate maps.</p><p><strong>Results: </strong>From the 50 million inhabitants, the average prevalence and incidence of MSVI were 13.94 and 13.34 between 2015 and 2019, respectively, while for blindness, they were 4.03 and 3.53. Females accounted for most reported cases, and there was a notable shift towards individuals over 50 years (<i>p</i> < 0.001). Valle del Cauca was the region with the most cases reported and the greatest disease burden.</p><p><strong>Conclusion: </strong>This is the first nationwide population-based study describing the prevalence, incidence, and sociodemographic characterization of blindness and MSVI in Colombia. In recent years, there has been an increased number of cases, prevalence, and incidence, with females over 50 particularly affected. This research provides insight into the country's vision impairment epidemiology landscape and contributes to formulating public health policies to improve eye health care.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"87-94"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140855751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2025-02-01Epub Date: 2024-05-08DOI: 10.1080/09286586.2024.2343725
Ali G Hamedani, Allison W Willis, Gui-Shuang Ying
{"title":"Self-reported Visual Difficulty, Age-related Eye Disease, and Neuropsychiatric Outcomes in Older Adults.","authors":"Ali G Hamedani, Allison W Willis, Gui-Shuang Ying","doi":"10.1080/09286586.2024.2343725","DOIUrl":"10.1080/09286586.2024.2343725","url":null,"abstract":"<p><strong>Purpose: </strong>Self-reported visual difficulty is consistently associated with dementia and other neuropsychiatric outcomes, but studies of specific age-related eye diseases have yielded conflicting results.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study using data from The National Health and Aging Trends Study, an ongoing nationally representative survey of older U.S. adults (<i>n</i> = 10,089). All subjects are screened for self-reported visual difficulty annually. Using linked Medicare claims data, we identified subjects with age-related macular degeneration (AMD), primary open-angle glaucoma (POAG), diabetic retinopathy, and cataract. For each condition, controls with complete Medicare eligibility and at least one eye care encounter were selected. We used semiparametric discrete time proportional hazards models to measure associations with incident dementia, and generalized estimating equations to examine longitudinal associations with depression, anxiety, and hallucinations, adjusting for baseline demographics and time-varying comorbidities.</p><p><strong>Results: </strong>Self-reported visual difficulty was associated with dementia (HR 1.16, 95% CI: 1.00-1.34), depression (OR 1.14, 95% CI: 1.04-1.26), anxiety (OR 1.17, 95% CI: 1.06-1.29), and hallucinations (OR 1.54, 95% CI: 1.29-1.84). Diabetic retinopathy was associated with depression (OR 1.31, 95% CI: 1.05-1.64), and cataracts were associated with a lower risk of depression (OR 0.84, 95% CI: 0.74-0.95) and anxiety (OR 0.86, 95% CI: 0.75-0.99). There were no other associations between age-related eye disease and neuropsychiatric outcomes.</p><p><strong>Conclusion: </strong>Self-reported visual difficulty is associated with dementia and other neuropsychiatric outcomes to a greater degree than age-related eye disease. These findings highlight the distinction between self-reported vision and clinically diagnosed eye disease with regard to health outcomes in older adults.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"103-111"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ophthalmic epidemiologyPub Date : 2025-02-01Epub Date: 2024-03-25DOI: 10.1080/09286586.2024.2330386
Germán Mejía-Salgado, Carlos Cifuentes-González, Laura Zarate-Pinzón, Luisa Fernanda Peña-Pulgar, William Rojas-Carabali, David Valdés-Arias, Danna Lesley Cruz, Alejandra de-la-Torre
{"title":"Colombian Ocular Diseases Epidemiology Study (CODES): Prevalence and Sociodemographic Characterization of Refractive Errors in Colombian Eye Care Consultations.","authors":"Germán Mejía-Salgado, Carlos Cifuentes-González, Laura Zarate-Pinzón, Luisa Fernanda Peña-Pulgar, William Rojas-Carabali, David Valdés-Arias, Danna Lesley Cruz, Alejandra de-la-Torre","doi":"10.1080/09286586.2024.2330386","DOIUrl":"10.1080/09286586.2024.2330386","url":null,"abstract":"<p><strong>Purpose: </strong>To estimate the prevalence and demographic characteristics of uncorrected refractive errors (URE) in people who attended eye care consultations in Colombia between 2015 and 2019, using the National Health Registry data.</p><p><strong>Methods: </strong>We identified ICD codes for myopia (H-52.1), degenerative myopia (H-44.2), hyperopia (H-52.0), and astigmatism (H-52.2) from the Integrated Social Protection Information System. Crude prevalence rates by age and sex were calculated for the population attending eye care services during these years. Additionally, we developed a standardized morbidity map across county departments.</p><p><strong>Results: </strong>In Colombia, the prevalence of URE among eye care consultations was 30.26%, increasing from 30.39% in 2015 to 35.14% in 2019. Of the 1,579,778 cases analyzed, 60.9% were females. Astigmatism emerged as the most prevalent URE, predominantly seen in individuals under 40 years old. Myopia showed the highest prevalence in the 10-30 age group, whereas hyperopia was most prevalent in the first decade of life. Geographically, the Andean region recorded most of URE cases, while more remote areas have seen a rising morbidity risk in recent years.</p><p><strong>Conclusions: </strong>The rising trend of URE in Colombia and its demographic and geographical variations underscores the urgent need for health professionals and government authorities to acknowledge and address this issue. This study provides crucial insights into the refractive error landscape across the country, highlighting the necessity for prevention programs specifically designed to cater to the country's unique needs.</p>","PeriodicalId":19607,"journal":{"name":"Ophthalmic epidemiology","volume":" ","pages":"52-60"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140288611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}