Shifting Paradigms in Glaucoma Management: A Retrospective Analysis from 2013 to 2023.

IF 1.7 4区 医学 Q3 OPHTHALMOLOGY
Ye Lin Kwan, Qilian Sheng, Yanan Sun, Yue Ying, Ruyi Zhai, Xiangmei Kong
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引用次数: 0

Abstract

Purpose: This study analyzes trends in glaucoma surgical management at the Eye & ENT Hospital of Fudan University over a 10-year period (2013-2023), focusing on the evolution of surgical practices and the adoption of new techniques.

Methods: A retrospective observational study was conducted using medical records of patients diagnosed with glaucoma who underwent surgery between January 1, 2013, and December 31, 2023. Data were analyzed using the Cochrane-Armitage trend test.

Results: A total of 13,092 glaucoma surgeries were performed, increasing from 736 in 2013 to 2,451 in 2023. Primary angle-closure glaucoma (PACG) accounted for 71.00% (9247/13092) of cases. Patients were predominantly aged 40-64 (43.56%) and 65+ (41.12%), with 56.60% female and 43.40% male. Internal filtration surgeries dropped between 2013-2015 but rose from 2.95% (26/880) in 2015 to 7.87% (193/2451) in 2023. External filtration surgeries declined from 82.47% (607/736) to 26.56% (651/2451). Phacoemulsification combined with goniosynechialysis (Phaco+GSL) increased from 7.61% (56/736) to 65.36% (1602/2451), while cyclodestruction procedures remained stable (0.54% to 0.20%). In congenital glaucoma (CG), ab interno trabeculotomy rose to 52.74% (77/146) by 2023. External filtration for primary open-angle glaucoma (POAG) decreased from 98.54% (135/137) to 74.82% (312/417), while Phaco+GSL for PACG increased from 11.43% (56/490) to 84.36% (1591/1886). Among glaucoma drainage devices (GDDs), Ahmed Glaucoma Valve usage declined from 94.25% (246/261) to 61.66% (193/313), while the Ex-Press device was phased out, and XEN Gel Stent (MIGS) usage rose to 38.34% (120/313).

Conclusion: Glaucoma surgical management at the Eye & ENT Hospital of Fudan University has evolved significantly over the past decade, with a notable shift towards minimally invasive procedures and personalized treatment strategies.

青光眼治疗模式的转变:2013 - 2023年回顾性分析
目的:本研究分析复旦大学附属眼耳鼻喉科医院近10年(2013-2023年)青光眼手术治疗的趋势,重点关注手术实践的演变和新技术的采用。方法:回顾性观察分析2013年1月1日至2023年12月31日青光眼手术患者的病历。数据分析采用Cochrane-Armitage趋势检验。结果:共实施青光眼手术13092例,由2013年的736例增加到2023年的2451例。原发性闭角型青光眼(PACG)占71.00%(9247/13092)。患者年龄以40 ~ 64岁(43.56%)和65岁以上(41.12%)为主,女性占56.60%,男性占43.40%。内滤手术在2013-2015年间有所下降,但从2015年的2.95%(26/880)上升到2023年的7.87%(193/2451)。体外滤过手术由82.47%(607/736)下降至26.56%(651/2451)。超声乳化联合卵囊协同作用(Phaco+GSL)从7.61%(56/736)上升至65.36%(1602/2451),环破坏程序保持稳定(0.54% ~ 0.20%)。到2023年,先天性青光眼(CG)的小梁间切开术比例上升至52.74%(77/146)。原发性开角型青光眼(POAG)外滤由98.54%(135/137)下降至74.82% (312/417),PACG外滤由11.43%(56/490)上升至84.36%(1591/1886)。在青光眼引流装置(GDDs)中,Ahmed glaucoma Valve的使用率从94.25%(266 /261)下降到61.66%(193/313),而Ex-Press装置被逐步淘汰,XEN Gel Stent (MIGS)的使用率上升到38.34%(120/313)。结论:在过去的十年中,复旦大学眼科医院青光眼手术管理发生了显著的变化,向微创手术和个性化治疗策略转变。
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来源期刊
Ophthalmic epidemiology
Ophthalmic epidemiology 医学-眼科学
CiteScore
3.70
自引率
5.60%
发文量
61
审稿时长
6-12 weeks
期刊介绍: Ophthalmic Epidemiology is dedicated to the publication of original research into eye and vision health in the fields of epidemiology, public health and the prevention of blindness. Ophthalmic Epidemiology publishes editorials, original research reports, systematic reviews and meta-analysis articles, brief communications and letters to the editor on all subjects related to ophthalmic epidemiology. A broad range of topics is suitable, such as: evaluating the risk of ocular diseases, general and specific study designs, screening program implementation and evaluation, eye health care access, delivery and outcomes, therapeutic efficacy or effectiveness, disease prognosis and quality of life, cost-benefit analysis, biostatistical theory and risk factor analysis. We are looking to expand our engagement with reports of international interest, including those regarding problems affecting developing countries, although reports from all over the world potentially are suitable. Clinical case reports, small case series (not enough for a cohort analysis) articles and animal research reports are not appropriate for this journal.
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