Optics letters最新文献_第4页

Deep learning-based temporal deconvolution for photon time-of-flight distribution retrieval. 基于深度学习的光子飞行时间分布检索时间解卷积。

IF 3.1 2区物理与天体物理

Optics letters Pub Date : 2024-11-15 DOI: 10.1364/OL.533923

Vikas Pandey, Ismail Erbas, Xavier Michalet, Arin Ulku, Claudio Bruschini, Edoardo Charbon, Margarida Barroso, Xavier Intes

{"title":"Deep learning-based temporal deconvolution for photon time-of-flight distribution retrieval.","authors":"Vikas Pandey, Ismail Erbas, Xavier Michalet, Arin Ulku, Claudio Bruschini, Edoardo Charbon, Margarida Barroso, Xavier Intes","doi":"10.1364/OL.533923","DOIUrl":"10.1364/OL.533923","url":null,"abstract":"The acquisition of the time of flight (ToF) of photons has found numerous applications in the biomedical field. Over the last decades, a few strategies have been proposed to deconvolve the temporal instrument response function (IRF) that distorts the experimental time-resolved data. However, these methods require burdensome computational strategies and regularization terms to mitigate noise contributions. Herein, we propose a deep learning model specifically to perform the deconvolution task in fluorescence lifetime imaging (FLI). The model is trained and validated with representative simulated FLI data with the goal of retrieving the true photon ToF distribution. Its performance and robustness are validated with well-controlled in vitro experiments using three time-resolved imaging modalities with markedly different temporal IRFs. The model aptitude is further established with in vivo preclinical investigation. Overall, these in vitro and in vivo validations demonstrate the flexibility and accuracy of deep learning model-based deconvolution in time-resolved FLI and diffuse optical imaging.","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"49 22","pages":"6457-6460"},"PeriodicalIF":3.1,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

112° field of view high-resolution swept-source OCT angiography for rat retinas. 用于大鼠视网膜的 112° 视场高分辨率扫源 OCT 血管造影。

IF 3.1 2区物理与天体物理

Optics letters Pub Date : 2024-11-15 DOI: 10.1364/OL.538165

Guangru B Liang, Shuibin Ni, Tristan T Hormel, John C Morrison, Diana C Lozano, Yifan Jian, J Peter Campbell, Yali Jia

{"title":"112° field of view high-resolution swept-source OCT angiography for rat retinas.","authors":"Guangru B Liang, Shuibin Ni, Tristan T Hormel, John C Morrison, Diana C Lozano, Yifan Jian, J Peter Campbell, Yali Jia","doi":"10.1364/OL.538165","DOIUrl":"https://doi.org/10.1364/OL.538165","url":null,"abstract":"This study introduces an ultra-wide field (UWF) and high-resolution swept-source optical coherence tomographic angiography (OCTA) system for rat retinal imaging. Using an asymmetrical optics design, the system achieves unprecedented details of retinal structures and vascular plexuses over a large field of view (112°) in a single-shot acquisition. Views of single-nerve fiber bundles and single capillary vessels are consistently visible over a 112° field of view. The system has a long imaging range and high penetration and allows a full view of vitreous hyaloid vessels, retina, choroid, sclera, and posterior ciliary arteries, down to sub-sclera connective tissues. In a longitudinal study of oxygen-induced retinopathy (OIR) in rats, the system successfully revealed the progression and regression of OIR-related vascular pathologies, such as ischemia, neovascularization, and tortuosity. To our knowledge, this novel UWF-OCT/OCTA prototype designed for rat retinal imaging will be a vital tool for monitoring disease progression and evaluating therapeutic interventions in preclinical models.","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"49 22","pages":"6449-6452"},"PeriodicalIF":3.1,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Goos-Hänchen shift for an Airyprime beam. Airyprime 光束的 Goos-Hänchen 移位。

IF 3.1 2区物理与天体物理

Optics letters Pub Date : 2024-11-15 DOI: 10.1364/OL.539499

Ze Chen, Shi-Yu Peng, Zhi-Hai Zhang, Jianli Liu, Yang Meng

引用次数: 0

Low-noise 2-GHz figure-9 fiber laser based on passive harmonic mode-locking. 基于无源谐波锁模的低噪声 2-GHz 图 9 光纤激光器。

IF 3.1 2区物理与天体物理

Optics letters Pub Date : 2024-11-15 DOI: 10.1364/OL.538386

Jindong Ma, Menglong Ma, Huanhuan Liu, Perry Ping Shum

引用次数: 0

Ptychographic Mueller matrix imaging (PMMI): principle and proof-of-concept demonstration. 分层穆勒矩阵成像（PMMI）：原理和概念验证演示。

IF 3.1 2区物理与天体物理

Optics letters Pub Date : 2024-11-15 DOI: 10.1364/OL.539100

Ming Gong, Li Liu, Jinxiang Du, Bailin Zhuang, Jiamin Liu, Honggang Gu, Shiyuan Liu

{"title":"Ptychographic Mueller matrix imaging (PMMI): principle and proof-of-concept demonstration.","authors":"Ming Gong, Li Liu, Jinxiang Du, Bailin Zhuang, Jiamin Liu, Honggang Gu, Shiyuan Liu","doi":"10.1364/OL.539100","DOIUrl":"10.1364/OL.539100","url":null,"abstract":"Quantitative characterization of optical anisotropies is extremely important for wide fields and applications. The Mueller matrix, providing all the polarization-related properties of a medium, is a powerful tool for the comprehensive evaluation of optical anisotropies. Here, we propose a ptychographic Mueller matrix imaging (PMMI) technique, which features the Mueller matrix polarization modulation being introduced into the ptychography. The ptychographic reconstruction is performed for each polarization state, and the Mueller matrix can be determined from the reconstructed polarization-modulated amplitude images. A proof-of-concept of the proposed PMMI is implemented, and both simulations and experiments are conducted to demonstrate the validity of the method. Results indicate that the imaging resolution of the home-built PMMI apparatus achieves 1.550 µm at the wavelength of 633 nm, which is of the highest level for the Mueller matrix imaging to the best of our knowledge. A customized birefringent specimen is characterized, and both retardance and axis azimuth are quantitatively evaluated.","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"49 22","pages":"6409-6412"},"PeriodicalIF":3.1,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Superconducting nanowire single-photon detector enhanced near-infrared II portable confocal microscopy for tissue imaging with indocyanine green. 超导纳米线单光子探测器增强型近红外 II 便携式共聚焦显微镜，用于吲哚菁绿的组织成像。

IF 3.1 2区物理与天体物理

Optics letters Pub Date : 2024-11-15 DOI: 10.1364/OL.537612

Yifan Liu, Cheng-You Yao, Timothy M Rambo, Bo Li, Aniwat Juhong, Jeremy S Doredla, Gary D Luker, Ming Han, Aaron J Miller, Zhen Qiu

{"title":"Superconducting nanowire single-photon detector enhanced near-infrared II portable confocal microscopy for tissue imaging with indocyanine green.","authors":"Yifan Liu, Cheng-You Yao, Timothy M Rambo, Bo Li, Aniwat Juhong, Jeremy S Doredla, Gary D Luker, Ming Han, Aaron J Miller, Zhen Qiu","doi":"10.1364/OL.537612","DOIUrl":"10.1364/OL.537612","url":null,"abstract":"In this Letter a novel, to our knowledge, approach for near-infrared (NIR) fluorescence portable confocal microscopy is introduced, aiming to enhance fluorescence imaging of biological samples in the NIR-II window. By integrating a superconducting nanowire single-photon detector (SNSPD) into a confocal microscopy, we have significantly leveraged the detection efficiency of the NIR-II fluorescence signal from indocyanine green (ICG), an FDA-approved dye known for its NIR-II fluorescence capabilities. The SNSPD, characterized by its extremely low dark count rate and optimized NIR system detection efficiency, enables the excitation of ICG with 1 mW and the capture of low-light fluorescence signals from deep regions (up to 512 µm). Consequently, our technique was able to produce high-resolution images of bio samples with a superior signal-to-noise ratio, making a substantial advancement in the field of fluorescence microscopy and offering a promising opportunity for future clinical study.","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"49 22","pages":"6349-6352"},"PeriodicalIF":3.1,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Viewing angle controller using two parallel alignment liquid crystal cells for automotive systems. 使用两个平行排列液晶单元的汽车系统视角控制器。

IF 3.1 2区物理与天体物理

Optics letters Pub Date : 2024-11-15 DOI: 10.1364/OL.539810

Zihan Zhou, Wenxin Lu, Rui Niu, Ruolong Lin, Hongmei Ma, Yubao Sun

引用次数: 0

Mid-infrared edge-enhanced imaging via angle-selective nonlinear filtering. 通过角度选择性非线性滤波实现中红外边缘增强成像。

IF 3.1 2区物理与天体物理

Optics letters Pub Date : 2024-11-15 DOI: 10.1364/OL.539700

Zhuohang Wei, Kun Huang, Jianan Fang, Heping Zeng

引用次数: 0

Miniaturized on-chip optical differentiator based on 2F-structured metasurfaces. 基于 2F 结构元表面的微型片上光学分辨器。

IF 3.1 2区物理与天体物理

Optics letters Pub Date : 2024-11-15 DOI: 10.1364/OL.542939

Hanting Ding, Chao Chen, Yu Yu

{"title":"Miniaturized on-chip optical differentiator based on 2F-structured metasurfaces.","authors":"Hanting Ding, Chao Chen, Yu Yu","doi":"10.1364/OL.542939","DOIUrl":"10.1364/OL.542939","url":null,"abstract":"Analog optical computing based on Fourier optics has attracted ever-growing attention, offering unprecedented low power consumption and high parallelism computation at the speed of light. Typically, classical optical 4F systems have been widely employed as one of the most common approaches for analog optical computing. However, most existing schemes replicate the original architecture relying on two Fourier transforms and one spatial-frequency filtering, resulting in bulky size and complex structure. Here, we propose a novel, to the best of our knowledge, on-chip 2F structure that achieves ultra-miniaturized optical analog computing. Taking advantage of the exceptional design flexibility of metasurfaces, we reduce the optical path length through a combination of phase compensation and complex amplitude modulation, thereby significantly simplifying the system structure without sacrificing accuracy compared to the traditional 4F system. As a proof-of-concept demonstration, we design and fabricate an on-chip optical differentiator on a silicon-on-insulator platform, achieving 84.01% and 79.81% differentiation accuracy in simulation and experiment, respectively.","PeriodicalId":19540,"journal":{"name":"Optics letters","volume":"49 22","pages":"6585-6588"},"PeriodicalIF":3.1,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frequency shift caused by a magnetic field and light intensity inhomogeneity in an optically detected clock. 光学检测时钟中磁场和光强不均匀引起的频移。

IF 3.1 2区物理与天体物理

Optics letters Pub Date : 2024-11-15 DOI: 10.1364/OL.538126

Yuanhao Li, Chen Liu, Sifei Chen, Lifeng Fan, Hangzhe Lyu, Chen Feng, Jian Duan, Yanhui Wang

引用次数: 0