Open Veterinary Journal最新文献

{"title":"Rehabilitation of chronic pain and enhanced healing in feline femoral surgery: A case report on laser therapy.","authors":"Dženita Hadžijunuzović Alagić, Kenan Baltić, Sabina Kolašinac, Nejra Hadžimusić","doi":"10.5455/OVJ.2024.v15.i1.43","DOIUrl":"10.5455/OVJ.2024.v15.i1.43","url":null,"abstract":"<p><strong>Background: </strong>Chronic pain and delayed bone healing are significant challenges in veterinary rehabilitation following orthopedic surgeries in cats. These issues necessitate advanced modalities for effective management. Laser therapy (LT), also known as photobiomodulation, has shown promise in promoting tissue repair and alleviating pain but remains underused in feline cases. This case report aims to evaluate the efficacy of LT in managing chronic pain and enhancing bone healing in a cat following femoral surgery complicated by orthopedic implant failure.</p><p><strong>Case description: </strong>A 7-year-old cat presented with persistent lameness and discomfort 3 years post-femoral fracture surgery. Despite initial surgical stabilization, chronic pain and restricted mobility persisted, leading to implant removal. After surgery, the cat underwent 25 sessions of LT using an 810-nm infrared semiconductor laser at a dosage of 6 J. Treatment sessions were conducted over 2 months, beginning 4 days post-surgery. Clinical and radiographic evaluations were performed to assess therapeutic outcomes. The cat demonstrated marked improvement in weight-bearing and mobility, with reduced signs of pain. Radiographic imaging revealed significant bone remodeling and consolidation. The owner reported enhanced activity levels and overall quality of life for the cat. These findings suggest that LT effectively facilitated bone healing and chronic pain relief in this case.</p><p><strong>Conclusion: </strong>LT proved to be a valuable component of multimodal rehabilitation in this feline patient, addressing both chronic pain and delayed bone healing. This case underscores the importance of integrating advanced therapeutic modalities into veterinary practice, particularly for complex orthopedic cases. Further research is recommended to validate these findings in larger, controlled studies.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 1","pages":"471-477"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intestinal helminths infection of Reithrodontomys mexicanus (Rodentia: Cricetidae) from a Suburban Area in Medellín, Colombia.","authors":"Horwald A B Llano, Itzel López Aguilar, Natalia Granda Orozco, Laura Gutiérrez Giraldo, Gloria Sánchez Zapata, Daisy Gómez Ruíz","doi":"10.5455/OVJ.2024.v15.i1.42","DOIUrl":"10.5455/OVJ.2024.v15.i1.42","url":null,"abstract":"<p><strong>Background: </strong>Gastrointestinal parasites associated with small wild rodents in Colombia remain poorly understood.</p><p><strong>Aim: </strong>This study aimed to identify the intestinal helminths of <i>Reithrodontomys mexicanus,</i> a common wild rodent species, in rural areas of Medellín, Colombia.</p><p><strong>Methods: </strong>Between June and December 2022, 31 individuals were captured and sex-classified. Fecal samples underwent flotation and sedimentation analysis.</p><p><strong>Results: </strong>The overall helminth prevalence in <i>R. mexicanus</i> was 67.7% (21/31). Identified helminth egg morphotypes included: Ascarid (types 1 and 2), Dicrocoeliidae-like (types 1 and 2), <i>Physaloptera</i> sp., <i>Strongyloides</i> sp., <i>Trichuris</i> sp., and two unidentified nematode eggs.</p><p><strong>Conclusion: </strong>This study reveals that <i>R. mexicanus</i> hosts a diverse range of parasites, including those with significant public health implications such as <i>Ascaris</i> spp., <i>Dicrocoelium</i> spp., and <i>Trichuris</i> spp. Our findings contribute to the understanding of wild rodent helminth fauna in South America and provide the first documentation of parasites in <i>R. mexicanus</i>.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 1","pages":"465-470"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a feed supplement containing probiotics on fecal score and clinical parameters in dogs with chronic kidney disease and intestinal disorders: A pilot study.","authors":"Francesca Perondi, Ilaria Lippi, Natascia Bruni, Nicolò Lonigro, And Elisa Martello","doi":"10.5455/OVJ.2024.v15.i1.29","DOIUrl":"10.5455/OVJ.2024.v15.i1.29","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease (CKD) in dogs is often accompanied by dysbiosis and abnormal gut microbiota composition, leading to gastrointestinal issues. Probiotics, including <i>Lactobacillus acidophilus</i>, <i>Enterococcus faecium</i>, and <i>Saccharomyces cerevisiae</i>, have shown promise in maintaining a healthy gut microbiota in both healthy and CKD animals.</p><p><strong>Aim: </strong>This pilot double-blinded, randomized controlled study aimed to assess the effects of a feed supplement containing these probiotics on clinical parameters and fecal consistency in dogs with CKD and intestinal disorders.</p><p><strong>Methods: </strong>Eight dogs with CKD were randomly assigned to receive the supplement (TRT, <i>n</i> = 4) or placebo (CTR, <i>n</i> = 4) alongside a renal commercial complete dietetic feed and another supplement specific for CKD for 50 days. Clinical parameters, such as body condition score and fecal score, were regularly monitored.</p><p><strong>Results: </strong>The dogs in the TRT group exhibited improvements in fecal consistency and clinical parameters compared with the CTR group.</p><p><strong>Conclusion: </strong>The feed supplement under investigation seems beneficial for improving clinical conditions, gut health, and stool quality in dogs with CKD. Future studies with larger sample sizes and microbiota analyses are needed to gain a better understanding of the potential benefits of this supplement in managing CKD in dogs.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 1","pages":"307-313"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometric and richness analysis of free-living and parasite taxa-invading street wetlands in Port Said, Egypt.","authors":"Hadeer Abd El-Hak Rashed, Layla Omran Elmajdoub, Eman Fayad, Ali Hussein Abu Almaaty","doi":"10.5455/OVJ.2024.v15.i1.30","DOIUrl":"10.5455/OVJ.2024.v15.i1.30","url":null,"abstract":"<p><strong>Background: </strong>Protists and helminths are considered the main organisms invading different cultures, especially aquatic organisms. Morphometric characteristics remain the most trustworthy descriptors of species identification or, more broadly, pattern recognition.</p><p><strong>Aim: </strong>This study aimed to provide morphological descriptions of the most prevalent Protista and helminths found in various street wetlands in Port Said, Egypt.</p><p><strong>Methods: </strong>This study collected three water samples per area each month. The samples were sent to the Parasitology Laboratory at Port Said University, Egypt. The samples were analyzed in two ways according to organism size. Large helminths were observed within 24 hours using a microscope, and their movements were recorded. Protists and helminth eggs were isolated by filtering water through a 0.45 μm cellulose acetate filter, followed by centrifugation. The isolated organisms were counted and imaged.</p><p><strong>Results: </strong>Nine dominant organisms were identified in the collected samples, including five parasitic species (<i>Protoopalina</i> sp., <i>Balantidium coli</i>, <i>Entamoeba</i> sp., <i>Fasciola</i> sp., and <i>Haemonchus</i> sp.) and four free-living species (<i>Paramecium</i> sp., <i>Euplotes</i> sp., <i>Echiniscus</i> sp., and <i>Aeolosoma</i> sp.). <i>Protoopalina</i> sp. was the most abundant parasite (17.6%), exhibiting a cylindrical, elongated shape (97.3-139 µm in length, 30-48 µm in width). <i>Euplotes</i> sp. were the free-living organisms (17%), measuring 59.7-66.5 µm in length and 32.1-42.5 µm in width, featuring cirri and dark bristles. <i>Paramecium</i> sp., with lengths between 161 and 256 µm, was spindle-shaped and had visible contractile vacuoles. <i>B. coli</i> trophozoites measured 60-107 µm in length and 46.5-83.3 µm in width, with a large posterior macronucleus. <i>Haemonchus</i> sp. larvae were about 700 µm long, with a distinct tail filament assisting their complex movement.</p><p><strong>Conclusion: </strong>The street wetlands in the surveyed area contain various free-living and pathogenic taxa. There is a need to link the presence of these organisms to physicochemical analyses. Future studies should prioritize broader geographic sampling, the integration of molecular techniques, and the exploration of host-parasite relationships.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 1","pages":"314-324"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling the morphological and molecular profile of Setaria digitata in Aceh cattle.","authors":"Teuku Zahrial Helmi, Farida Farida, Aisyah Kasturi, Ella Prisa Lusisia Rahmah, Winaruddin Winaruddin, Muhammad Hanafiah","doi":"10.5455/OVJ.2024.v15.i1.18","DOIUrl":"10.5455/OVJ.2024.v15.i1.18","url":null,"abstract":"<p><strong>Background: </strong>The <i>Setaria</i> nematode, classified within the order <i>Spirurida</i> and family <i>Setariidae</i>, has predilection in the peritoneal cavity of its host, with mosquitoes acting as vectors for transmitting microfilariae to cattle, its primary host.</p><p><strong>Aim: </strong>This study investigates the morphology and molecular characteristics of <i>Setaria digitata</i> in Aceh cattle and evaluates the effectiveness of three staining solutions lactophenol, glycerol, and lugol 2% for visualizing adult worms.</p><p><strong>Methods: </strong>A total of 124 blood serum and adult worm samples were collected from Aceh cattle at slaughterhouses in Banda Aceh and Bireuen. Microfilariae detection was conducted using the Knott test, while worm morphology was assessed via polymerase chain reaction amplification of the 12S rDNA and cox1 genes.</p><p><strong>Results: </strong>Each staining solution enhanced worm morphology visualization with varying benefits. The Lugol 2% solution offered a complete view of morphology but lacked detail for internal structures. Lactophenol improved the visibility of both morphology and internal organs, though sample integrity declined quickly. Glycerol displayed both the morphology and internal structures with clarity, making it the most effective option overall. Molecular amplification results showed a 450 bp band for the 12S rDNA gene and a 680 bp band for the cox1 gene in <i>S. digitata</i>.</p><p><strong>Conclusion: </strong>Glycerol proved superior for maintaining morphology and visualizing the internal structures of <i>S. digitata</i>. Molecular profiling using the 12S rDNA and cox1 genes effectively confirmed the identity of <i>S. digitata</i>, underscoring the value of these genetic markers for species identification.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 1","pages":"187-197"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined extracts of <i>Curcuma longa</i> and <i>Curcuma zedoaria</i> ameliorates cisplatin-induced kidney damage in rats.","authors":"Putri Reno Intan, Sukmayati Alegantina, Hidayatul Fajri, Fitrine Ekawasti, Ani Isnawati, Lisa Andriani Lienggonegoro, Uly Alfi Nikmah, Sunarno Sunarno, Sela Septima Mariya, Lina Noviyanti Sutardi, Agus Setiyono, Ekowati Handharyani","doi":"10.5455/OVJ.2024.v15.i1.38","DOIUrl":"10.5455/OVJ.2024.v15.i1.38","url":null,"abstract":"<p><strong>Background: </strong>Cisplatin (CIS) is a highly effective chemotherapeutic drug. However, it is associated with various side effects, including kidney damage, due to its nephrotoxic properties.</p><p><strong>Aim: </strong>This study aimed to evaluate the renoprotective potential of the combined extract of <i>Curcuma longa</i> and <i>Curcuma zedoaria</i> in reducing nephrotoxicity by examining its effects on tumor necrosis factor-alpha (TNF-α), KIM-1, and caspase-3 levels.</p><p><strong>Methods: </strong>Twenty-five rats were divided into normal control groups (NS), CIS control groups, and three treatment groups that received doses of the combined extract at 100, 200, and 400 mg/kg (CUR100, CUR200, and CUR400), respectively, on day 1-20. All groups, except the NS group (receiving normal saline i.p.), received intraperitoneal CIS (1 mg/kg) on days 7 and 14 of the 20-day extract treatment.</p><p><strong>Results: </strong>Compared with the rats in the CIS group, rats given the combined extract had a considerable gain in body weight and decreased TNF-α, KIM-1, and caspase-3 expression levels. Histopathological examination revealed that the extract group experienced less kidney damage than the CIS group. The combined extract, administered at 200 mg/kg, exerted the most apparent protective effect, decreasing renal TNF-α, KIM-1, and caspase 3.</p><p><strong>Conclusion: </strong>The combined extract of <i>C. longa</i> and <i>C. zedoaria</i> has the potential to be a therapeutic agent for reducing nephrotoxicity by suppressing TNF-α, KIM-1, and caspase-3 levels. Further research is required to determine the potential of this combination therapy in humans.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 1","pages":"428-436"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First molecular evidence of hemotropic <i>mycoplasmas</i> in goats from Bosnia and Herzegovina.","authors":"Amela Livnjak, Nejra Hadžimusić, Hans Peter Fuehrer, Bita Shahi-Barogh, Jovana Šupić, Lejla Pašić","doi":"10.5455/OVJ.2024.v15.i1.25","DOIUrl":"10.5455/OVJ.2024.v15.i1.25","url":null,"abstract":"<p><strong>Background: </strong>Hemoplasmas represent the type of bacteria that infect red blood cells, potentially leading to various health impacts, including changes in blood parameters. The close interaction between hemoplasma and red blood cells results in cell damage through immune-related and other unspecified mechanisms. Even with a strong immune response and antibiotic treatment, affected animals are likely to remain chronic carriers once clinical symptoms have subsided. These microorganisms were previously documented in sheep and other small ruminants worldwide.</p><p><strong>Aim: </strong>Since there is a lack of research on the link between <i>Mycoplasma</i> infection and blood parameters, our aim was to investigate how <i>Mycoplasma</i> infection affects these blood parameters. In addition, the study conducted in Bosnia and Herzegovina represents the first documented research of hemoplasma infection in goats within this region.</p><p><strong>Methods: </strong>In this research, 20 Alpine goats were sampled to investigate the presence of hemoplasma using polymerase chain reaction (PCR) analysis. Sequences of the 16S rRNA gene fragments were identified subsequently. The effect of <i>Mycoplasma ovis</i> (<i>M. ovis</i>) infection was observed on the following hematological parameters: Red blood cell count (RBC), hematocrit (HCT), hemoglobin (HGB), mean cell volume (MCV), mean cell hemoglobin, mean cell hemoglobin concentration, Reticulocyte count, and white blood cell (WBC). Effect on white blood cell differentiation, absolute white blood cell counts, platelet count, and mean platelet volume were also investigated.</p><p><strong>Results: </strong>PCR analysis confirmed the presence of <i>Mycoplasma spp</i>. in 7 out of the 20 blood samples. Sequencing of the 16S rRNA gene fragments revealed that all positive samples were identified as <i>M. ovis</i>. The research findings highlighted potential effects on blood parameters in infected goats. Goats infected with <i>M. ovis</i> exhibited higher mean levels of HGB and HCT compared to uninfected goats. However, there were no statistically significant differences in RBC counts between infected and uninfected groups. The study also noted significantly higher WBC counts in goats without <i>M. ovis</i> infection.</p><p><strong>Conclusion: </strong>35% of animals tested positive for <i>M. ovis</i>. Our study's findings showed notable differences in hematological parameters between goats infected with <i>M. ovis</i> and those that were not infected.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 1","pages":"270-276"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroprotection effect of bovine umbilical mesenchymal stem cell-conditioned medium on the rat model of Alzheimer's disease mediated by upregulation of BDNF and NGF and downregulation of TNF-α and IL-1β.","authors":"Hevi Wihadmadyatami, Muhammad Ali Zulfikar, Herawati Herawati, Srikanth Karnati, Golda Rani Saragih, Dinda Aliffia, Dyah A O A Pratama, Nurrahmi Handayani, Ulayatul Kustiati, Dewi Ratih Tirtosari, Yudy Tjahjono","doi":"10.5455/OVJ.2024.v15.i1.14","DOIUrl":"10.5455/OVJ.2024.v15.i1.14","url":null,"abstract":"<p><strong>Background: </strong>Neurodegenerative diseases (NDDs) are distinguished by impairment and depletion of nerve cells; one of the most common NDDs is Alzheimer's disease (AD), which can appear in early onset or late onset. In recent years, the secretome or conditioned medium of mesenchymal stem cells has provided new hope for improving conditions and preventing AD. One of the secretomes is bovine umbilical mesenchymal stem cells-conditioned medium (BUMSC-CM), where BUMSC is predicted to promote neuronal proliferation potentially.</p><p><strong>Aim: </strong>This study analyzes the therapeutic efficiency of conditioned medium or secretome produced from BUMSC-CM in treating neurodegeneration in animal models of AD.</p><p><strong>Methods: </strong>Five groups consisting of 12 male rats were assigned: untreated (Group A, <i>n</i> = 5), positive control group given normal saline 1 ml/100 g BW (Group B, <i>n</i> = 5), AD rats model followed by Donepezil treatment (Group C, <i>n</i> = 5), AD rats model with BUMSC-CM 0.2 ml/kg BW post-trimethyltin (TMT) induction (Group D, <i>n</i> = 5), and AD rats model with BUMSC-CM 0.5 ml/kg BW post-TMT induction (Group E, <i>n</i> = 5). The brain samples were analyzed for neuronal density using cresyl violet staining. The expression and activity of brain-derived neurotrophic factor (BDNF) were analyzed by ELISA; in addition, interleukin 1beta (IL-1β), tumor necrotic factor-alpha (TNF-α), and neural growth factor (NGF) were analyzed by quantitative polymerase chain reaction. Interactions between the main substances of BUMSC-CM and beta-amyloid protein were visualized using <i>in silico</i> molecular docking.</p><p><strong>Results: </strong>Our result demonstrated that BUMSC-CM with the dosage of 0.5 ml/kg BW significantly increased BDNF concentration. We also found that BUMSC-CM with dosage 0.2 ml/kg BW and 0.5 ml/kg BW down-regulated IL-1β and TNF-α and upregulated NGF expression. Additionally, the number of neurons in AD rats post-treated with BUMSC-CM was significantly increasing. Furthermore, the amino acids in BUMSC-CM, including isoleucine, leucine, and valine, bind to the amyloid beta protein via interactions that are hydrophobic and hydrogen-bonded.</p><p><strong>Conclusion: </strong>In this study, the neuroprotective potential of BUMSC-CM was demonstrated by its ability to upregulate BDNF and NGF while downregulating IL-1β and TNF-α. Additionally, BUMSC-CM showed potential to promote neuron proliferation in the hippocampus regions of a rat AD model. The main constituents in BUMSC-CM adhere to amyloid beta protein, hence diminishing the likelihood of ND disorders, specifically AD.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 1","pages":"151-161"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wild fauna in Oman: Current situation and perspectives, with particular interest to turtles and ungulates.","authors":"Massimo Giangaspero, Salah Al Mahdhori, Sultan Al Bulushi, Ali Salim Bait Said, Metab Khalaf Salim Al Ghafri","doi":"10.5455/OVJ.2024.v15.i1.4","DOIUrl":"10.5455/OVJ.2024.v15.i1.4","url":null,"abstract":"<p><p>In order to achieve optimal health for humans, animals, and our environment, the ‟One Health\" approach proactively engages various disciplines, including environmental health sciences, veterinary medicine, and human medicine. Therefore, wildlife conservation assumes a relevant role in this context. The Sultanate of Oman is a country with an immense biodiversity. In recent decades, authorities have actively protected wildlife and the natural environment. In 1994, the Arabian Oryx Sanctuary was created under the patronage of the Royal Diwan. The Environment Authority was recently established, and the plan \"Vision 2040\" was conceived with the ambitious goal of Oman becoming one of the top 20 countries for wildlife protection. Two species, in particular, show the amplitude of the efforts necessary to preserve this natural heritage and their survival: the oryx of Arabia and the green turtle. The oryx is not only a national symbol but, from extinction in nature, its return is also a success for the Omani sanctuary. The green turtles elected the Omani coasts as the second reproduction site in the world. Therefore, the delicate equilibrium of wild fauna in Oman is required to be studied and supported.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 1","pages":"35-53"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of a gelatin-based hemostatic sponge and hydroxyapatite-chitosan nanocomposites (nHAp/CS) on regeneration of radial bone defects in rabbits.","authors":"Taher Naser Elmeshreghi, Fathy D El-Seddawy, Mohamed Gomaa, Shimaa A Ezzeldein, Mustafa Abd El Raouf","doi":"10.5455/OVJ.2024.v15.i1.19","DOIUrl":"10.5455/OVJ.2024.v15.i1.19","url":null,"abstract":"<p><strong>Background: </strong>Bone-graft substitutes are a frequently employed method for the clinical reconstruction of osseous bone defects, and research on synthetic biomaterials is currently ongoing. Absorbable hemostatic gelatin sponge and hydroxyapatite-chitosan nanocomposites (nHAp/CS) have gained popularity in recent years because of their inherent characteristics: osteogenesis, osteoconductivity, osteoinductivity, biodegradability, and biocompatibility.</p><p><strong>Aim: </strong>The aim of the study was to evaluate the effectiveness of 1) a gelatin-based hemostatic sponge (Surgispon) and 2) a combination of a weight ratio of 75/25 nHAp/CS composite with a Surgispon for osteogenic potential in the treatment of full-thickness segmental osseous defects in the radius of rabbits.</p><p><strong>Methods: </strong>The 18 New Zealand rabbits had 10-mm-induced segmental diaphyseal defects of the left limb radius and were randomly allocated into three groups: group I left the defects untreated (control group), group II used a Surgispon, and group III had a weight ratio of 75/25 nHAp/CS composite wrapped with a Surgispon. Quantitative evaluation of the bone repair at the defect site in each group (<i>n</i> = 6), radiographic, gross, computed tomography (CT), and histopathological examinations were performed at 6 weeks (<i>n</i> = 3) and 12 weeks (<i>n</i> = 3) postoperatively.</p><p><strong>Results: </strong>The quantitative statistical analysis of various evaluation methods at 6 weeks post-implantation demonstrated that there was no statistically significant difference between the groups (<i>p</i> > 0.05). The statistically significant differences (<i>p</i> < 0.05) between groups I and II, while groups I and III, were evident 12 weeks postoperatively.</p><p><strong>Conclusion: </strong>The findings of the radiographic, macroscopic, CT, and histopathological analyses firmly demonstrate that the combination of a 75/25 weight ratio composite of nHAp/CS with Surgispon is more effective than Surgispon alone in its ability to significantly increase bone formation. This could provide a prospective option for treating segmental bone defects.</p>","PeriodicalId":19531,"journal":{"name":"Open Veterinary Journal","volume":"15 1","pages":"198-210"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}