Ophthalmic and Physiological Optics最新文献

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Do myopia control spectacle lenses with defocus incorporated multiple segments technology alter visual parameters and cortical activity? 离焦结合多节段技术的近视控制眼镜是否会改变视觉参数和皮层活动?
IF 2.8 3区 医学
Ophthalmic and Physiological Optics Pub Date : 2025-06-01 Epub Date: 2025-04-16 DOI: 10.1111/opo.13513
Monika Wojtczak-Kwaśniewska, Mikołaj Domagalski, Maciej Dymczyk, Maria Padurska, Katarzyna Przekoracka, Anna Przekoracka-Krawczyk
{"title":"Do myopia control spectacle lenses with defocus incorporated multiple segments technology alter visual parameters and cortical activity?","authors":"Monika Wojtczak-Kwaśniewska, Mikołaj Domagalski, Maciej Dymczyk, Maria Padurska, Katarzyna Przekoracka, Anna Przekoracka-Krawczyk","doi":"10.1111/opo.13513","DOIUrl":"10.1111/opo.13513","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated visual parameters and cortical activity after wearing myopia control spectacle lenses with defocus incorporated multiple segments (DIMS).</p><p><strong>Methods: </strong>Myopic adults between 20 and 30 years of age were enrolled. The study consisted of (1) examination of visual parameters and (2) measurement of cortical responses, while wearing single vision lenses (SVL) and MiYOSMART (MS) lenses in counterbalanced order after a two-week adaptation period. Visual parameters tested were: high-contrast visual acuity (HCVA) and low-contrast visual acuity (LCVA), contrast sensitivity, heterophoria, near point of convergence (NPC), stereopsis, accommodative facility and the accommodative response. Cortical responses were assessed by visual evoked potentials (VEPs), recorded from 10 electrodes placed over the parieto-occipital area.</p><p><strong>Results: </strong>MiYOSMART lenses produced slightly better HCVA than SVL (-0.25 vs. -0.21 logMAR, p = 0.02) and a larger accommodative response (MS 1.68 D; SVL 1.53 D, p < 0.001). No significant differences in LCVA, heterophoria, NPC, stereopsis or contrast sensitivity were observed. The latencies and amplitudes of the early and late components of the VEPs (C1, N1, P1, P2) did not differ significantly between lenses.</p><p><strong>Conclusions: </strong>This study found no clinically significant differences in visual parameters or visual cortex responses between SVL and MS lenses after 2 weeks of adaptation. These results confirm the absence of adverse visual effects from DIMS lenses for myopia control.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"982-994"},"PeriodicalIF":2.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimising non-cycloplegic screening strategies for early detection of pre-myopia and myopia in young children. 优化非睫状体麻痹筛查策略,早期发现幼儿近视前期和近视。
IF 2.8 3区 医学
Ophthalmic and Physiological Optics Pub Date : 2025-05-14 DOI: 10.1111/opo.13525
Síofra Harrington, Michael Moore, James Loughman, Ian Flitcroft, Veronica O'Dwyer
{"title":"Optimising non-cycloplegic screening strategies for early detection of pre-myopia and myopia in young children.","authors":"Síofra Harrington, Michael Moore, James Loughman, Ian Flitcroft, Veronica O'Dwyer","doi":"10.1111/opo.13525","DOIUrl":"https://doi.org/10.1111/opo.13525","url":null,"abstract":"<p><strong>Purpose: </strong>Early detection of myopia is essential to delay its onset and progression. Pre-myopia, defined by an inadequate hyperopic reserve, increases myopia risk in childhood. However, effective screening methods remain limited. This study aimed to develop practical non-cycloplegic screening methods for pre-myopia and myopia in 6- to 7-year-olds to support earlier interventions.</p><p><strong>Methods: </strong>This cross-sectional study of 621 Irish schoolchildren (mean age: 7.12 ± 0.45 years; 51.8% boys) assessed uncorrected distance visual acuity (UDVA). Cycloplegic spherical equivalent refraction (SER) classified refractive status (myopia: SER ≤ -0.50D; pre-myopia: SER > -0.50 ≤ 0.75D). Pre- and post-cycloplegic SER were measured using the Welch Allyn Spot Vision Screener and Dong-Yang Rekto-ORK 11, respectively. Axial length (AL) and corneal radius (CR) were measured with the Zeiss IOLMaster and parental myopia history via questionnaire. Logistic regression and ROC curves evaluated non-cycloplegic screening methods.</p><p><strong>Results: </strong>Pre-myopia prevalence was 24.3% (95% confidence intervals (CI): 29.3-36.2), and myopia prevalence was 3.3% (CI: 2.5-5.5). UDVA screening had an area under the curve (AUC) (CI) = 0.72 (0.59-0.86) and 0.42 (0.36-0.47) for detecting myopia and pre-myopia, respectively. For pre-myopia discrimination, non-cycloplegic SER, AL, AL/CR and parental myopia had AUCs of 0.67 (0.62-0.72), 0.67 (0.62-0.72), 0.69 (0.64-0.74) and 0.59 (0.53-0.64), respectively. The best method combined non-cycloplegic SER and AL/CR (AUC = 0.72 (0.67-0.76)). Including UDVA or parental myopia did not improve results. For myopia detection, AUCs were non-cycloplegic SER:0.84 (0.72-0.97), AL:0.88 (0.82-0.95), AL/CR:0.84 (0.75-0.94) and parental myopia:0.62 (0.48-0.75). The best method combined AL and non-cycloplegic SER 0.94 (0.90-0.99). Adding parental myopia did not improve the AUC = 0.93 (0.87-0.99) but adding UDVA achieved an AUC = 0.95 (0.90-0.99).</p><p><strong>Conclusion: </strong>While UDVA alone provided acceptable discrimination for myopia, it was insufficient for screening pre-myopia. Non-cycloplegic SER alone had relatively poor discrimination for pre-myopia, but its performance improved when combined with the AL/CR ratio. The best results for myopia discrimination were achieved by combining non-cycloplegic SER, axial length and UDVA measures.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144033822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retinal shadows of multisegment lenses in fundus imaging. 眼底成像中多节段晶状体的视网膜阴影。
IF 2.8 3区 医学
Ophthalmic and Physiological Optics Pub Date : 2025-05-14 DOI: 10.1111/opo.13524
Arthur Ho, Lisa Feng, Jos J Rozema, David A Atchison
{"title":"Retinal shadows of multisegment lenses in fundus imaging.","authors":"Arthur Ho, Lisa Feng, Jos J Rozema, David A Atchison","doi":"10.1111/opo.13524","DOIUrl":"https://doi.org/10.1111/opo.13524","url":null,"abstract":"<p><strong>Purpose: </strong>To provide a more sophisticated explanation of the optics involved when retinal 'shadows' are seen in scanning laser ophthalmoscopic images during the wear of multisegment and diffusion optic spectacle lenses.</p><p><strong>Methods: </strong>Images were recorded with a system that uses a scanning broad line fundus imaging principle in participants with undilated pupils wearing a multisegment spectacle lens. The live infra-red preview display of the system was also acquired during image recording. Ray-tracing and image simulations were performed, assuming a Maxwellian illumination system in which a source was refracted first through a lens and then through a model of a multisegment spectacle lens focused onto the pupil of an eye model and hence to the retina. A detector surface was positioned slightly in front of the retina to record the irradiation distribution. The light source was varied from 0.1 μm to 1.8 mm in diameter to investigate the effect of light source size on retinal irradiation distribution.</p><p><strong>Results: </strong>The retinal shadow pattern was visible on the live infra-red preview display, as reported previously. However, the recorded images of the retina do not exhibit the same shadow pattern. The simulations predict that the circular shadows corresponding to lenslet positions become progressively less discernible with increasing light source size.</p><p><strong>Conclusion: </strong>An explanation is provided for the shadows on retinal images due to multisegment lenses, which may be observable under certain illumination conditions.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optical characterisation and vision quality assessment of two myopia control contact lenses. 两种近视控制隐形眼镜的光学特性及视力质量评价。
IF 2.8 3区 医学
Ophthalmic and Physiological Optics Pub Date : 2025-05-06 DOI: 10.1111/opo.13521
Josh Richards, Matt Jaskulski, Jill Woods, Sarah Guthrie, Pete Kollbaum
{"title":"Optical characterisation and vision quality assessment of two myopia control contact lenses.","authors":"Josh Richards, Matt Jaskulski, Jill Woods, Sarah Guthrie, Pete Kollbaum","doi":"10.1111/opo.13521","DOIUrl":"https://doi.org/10.1111/opo.13521","url":null,"abstract":"<p><strong>Purpose: </strong>This investigation examined the image and vision quality of two commercially available daily disposable myopia control soft contact lenses.</p><p><strong>Methods: </strong>Wavefront errors were measured with an SHS Ophthalmic aberrometer for two myopia control soft contact lenses: a coaxially designed dual-focus lens (omafilcon A, CooperVision MiSight® 1 day, MS1d) and a design employing multiple add powers that included non-coaxial optics in annular add zones (senofilcon A, Johnson & Johnson Vision ACUVUE® Abiliti™ 1-Day, AB). Geometric optics ray tracing generated point-spread functions and wave optics were used to compare modulation transfer functions (MTFs) and simulated letter images. Twenty-six myopic children completed a randomised, non-dispensing, contralateral double-masked clinical trial. After 1 h of wear, right and left eye visual acuity (VA), subjective vision quality and lens preference (Likert) were assessed while viewing monocularly.</p><p><strong>Results: </strong>The lens containing non-coaxial optics employed a small central zone with approximately +10.00 D of added power and two annular rings with a power gradient typical of non-coaxial optics. The coaxial design contained a centre zone with a distance correction and two annular zones with a fixed add power of approximately +2.00 D. MTFs and simulated images were better with small pupils, which was most noticeable with the coaxial design. Distance VA was -0.02 ± 0.04 with MS1d and 0.09 ± 0.08 with AB, p < 0.01. The majority of participants (77%) reported a preference for one lens; 54% preferred the MS1d and 23% preferred the AB lens.</p><p><strong>Conclusions: </strong>Myopia control contact lenses employing coaxial or a mixture of coaxial and non-coaxial optics both reduced retinal image contrast but successfully imaged high spatial frequencies and provided high quality of vision. Image and vision quality were slighly superior in the lens employing coaxial optics alone.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visual environmental risk factors in outdoor activities and near work and potential mechanisms. 户外活动及工作附近的视觉环境危险因素及潜在机制。
IF 2.8 3区 医学
Ophthalmic and Physiological Optics Pub Date : 2025-05-05 DOI: 10.1111/opo.13522
Dan-Lin Li, Carla Lanca, Seang-Mei Saw, Andrzej Grzybowski, Chen-Wei Pan
{"title":"Visual environmental risk factors in outdoor activities and near work and potential mechanisms.","authors":"Dan-Lin Li, Carla Lanca, Seang-Mei Saw, Andrzej Grzybowski, Chen-Wei Pan","doi":"10.1111/opo.13522","DOIUrl":"https://doi.org/10.1111/opo.13522","url":null,"abstract":"<p><strong>Purpose: </strong>Myopia is highly prevalent among children and adolescents and results from abnormal refractive development. Less outdoor time as well as more near work have been recognised as major risk factors for myopia. This study analysed the major environmental factors related to myopia, such as outdoor activities and near work, and reviewed the potential mechanisms of myopia development.</p><p><strong>Methods: </strong>A systematic search was conducted across PubMed, Web of Science, Cochrane Library and Ovid databases within the last two decades up to November 2024. This review followed the recommendations of the PRISMA Statement and only full-text review articles in English were included.</p><p><strong>Results: </strong>Summarising the findings from 13 review articles, the environmental risk factors for myopia included lighting features such as low illumination and monochromatic light as well as aspects of the visual scene, for example, the presence of low spatial frequencies and hyperopic defocus. These particular visual stimuli may contribute to the onset and progression of myopia and increase the risk of retinal disorders by reducing choroidal blood flow, leading to scleral hypoxia and remodelling. When analysing environmental risk factors, it is challenging to isolate the individual contributions of outdoor time and near work. Furthermore, previous studies used different definitions of environmental exposures.</p><p><strong>Conclusions: </strong>Future research needs quantitative, objective and standardised measures to improve the comparability and consistency between studies. In addition, work should focus on different ethnic populations and gene-environment studies, so as to determine the influence of environmental risk factors on myopia.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel wearable sensor for objective measurement of distance and illumination. 一种用于客观测量距离和照明的新型可穿戴传感器。
IF 2.8 3区 医学
Ophthalmic and Physiological Optics Pub Date : 2025-05-03 DOI: 10.1111/opo.13523
Raman Prasad Sah, Pavan Kalyan Narra, Lisa A Ostrin
{"title":"A novel wearable sensor for objective measurement of distance and illumination.","authors":"Raman Prasad Sah, Pavan Kalyan Narra, Lisa A Ostrin","doi":"10.1111/opo.13523","DOIUrl":"https://doi.org/10.1111/opo.13523","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the rangefinding and light sensing capabilities of a novel wearable sensor, the Visual Environment Evaluation Tool (VEET) developed for myopia research.</p><p><strong>Methods: </strong>The VEET 1.0 (Meta, LLC) is a temple-integrated system mounted on a spectacle frame. Both the left and right temples house four sensors each, angled straight ahead and 20° downward/4° nasal, respectively. For validation, VEET-mounted spectacles were placed on a mannequin head. An infrared camera was used to capture the spatial characteristics of the rangefinding beam. Distance measurements were collected against a wall for 5-400 cm. The accuracy of distance measurements for different target types, sizes and tilt was assessed. Ambient illumination was captured in different indoor and outdoor settings and compared to a lux meter.</p><p><strong>Results: </strong>All devices (N = 20) were capable of capturing distances for the full range evaluated, 5-400 cm, against a wall. There was a strong relationship between the actual and measured distances, with a slope of 1.01 ± 0.003 and 0.95 ± 0.007, for the left and right temples, respectively. Distance measurements were repeatable across different target types, including paper and tablet. Mean beam diameter of five tested devices was 52.2° ± 7.5°. The VEET effectively measured distances across different target sizes, ranging from 2 × 2 cm and larger and target tilt ±60°. Illumination measurements across different indoor and outdoor settings demonstrated a strong linear relationship with lux meter readings (R<sup>2</sup> = 0.99 and 0.78 for the left and right temples, respectively), effectively distinguishing indoor (<1000 lux) and outdoor (≥1000 lux) illumination levels.</p><p><strong>Conclusion: </strong>The VEET provides accurate quantification of real-time distances across different target types and sizes and is capable of effectively distinguishing indoor and outdoor illumination levels. The VEET will be valuable in studies evaluating risk factors for myopia to gain a better understanding of the role of near work and light exposure.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of macular sensitivity with posterior staphyloma in highly myopic eyes: Aier-SERI high myopia adult cohort study. 高度近视眼黄斑敏感性与后葡萄肿的关系:Aier-SERI高度近视成人队列研究。
IF 2.8 3区 医学
Ophthalmic and Physiological Optics Pub Date : 2025-05-01 Epub Date: 2025-02-20 DOI: 10.1111/opo.13467
Yanfeng Jiang, Li-Lian Foo, Ziqi Hu, Wei Pan, Kai-Xiong Cheong, Huanhuan Tan, Seang-Mei Saw, Quan V Hoang, Zhikuan Yang, Weizhong Lan
{"title":"Association of macular sensitivity with posterior staphyloma in highly myopic eyes: Aier-SERI high myopia adult cohort study.","authors":"Yanfeng Jiang, Li-Lian Foo, Ziqi Hu, Wei Pan, Kai-Xiong Cheong, Huanhuan Tan, Seang-Mei Saw, Quan V Hoang, Zhikuan Yang, Weizhong Lan","doi":"10.1111/opo.13467","DOIUrl":"10.1111/opo.13467","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to determine the relationship between macular sensitivity (MS) and posterior staphyloma (PS) in highly myopic eyes.</p><p><strong>Methods: </strong>This cross-sectional, observational study included 646 highly myopic eyes (spherical equivalent (SE) ≤-5.00D and the international meta-analysis for pathologic myopia classification grade of <2) from 362 participants. MS was measured using microperimetry and evaluated between eyes with and without PS. Correlations between MS and PS were determined in multivariate regression models.</p><p><strong>Results: </strong>Although there was no significant difference in best-corrected visual acuity (BCVA) (p = 0.07), the MS of the PS group was significantly lower than the no PS group at the central 2°, 4°, 6°, 8° and 10° (all p < 0.001). After controlling age, axial length (AL) and SE, the MS in the PS group was still lower than the no PS group from 2° to 10° (all p < 0.05). In a multivariable analysis adjusting for age, AL, SE and BCVA, the presence of PS was significantly associated with lower MS in the central 2°-10° (all p < 0.05).</p><p><strong>Conclusions: </strong>Lower MS was independently associated with the presence of PS in highly myopic eyes. Even when BCVA was not significantly different, MS still could reveal subtle changes in visual function in highly myopic eyes with PS.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"845-853"},"PeriodicalIF":2.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increasing myopia in Scotland at age of 3.5-5.5 years: A retrospective epidemiological study. 苏格兰3.5-5.5岁近视增加:一项回顾性流行病学研究
IF 2.8 3区 医学
Ophthalmic and Physiological Optics Pub Date : 2025-05-01 Epub Date: 2025-02-27 DOI: 10.1111/opo.13461
Bruce J W Evans, Lee Pentland, Benjamin E W Evans, David F Edgar, Rakhee Shah, Miriam L Conway
{"title":"Increasing myopia in Scotland at age of 3.5-5.5 years: A retrospective epidemiological study.","authors":"Bruce J W Evans, Lee Pentland, Benjamin E W Evans, David F Edgar, Rakhee Shah, Miriam L Conway","doi":"10.1111/opo.13461","DOIUrl":"10.1111/opo.13461","url":null,"abstract":"<p><strong>Purpose: </strong>Scotland has comprehensive child vision screening at age 3.5-5.5 years of age, with ~85% participation (40,000-50,000 screening episodes annually). Orthoptists deliver the screening, including presenting vision, cover test and other tests. Screening failures are referred for eye examinations, including cycloplegic refraction. The study aims to report refractive error data from these examinations (~5000-6000 annually) for 3 years before and 2 years following the COVID-19 pandemic, and to investigate correlations between myopia and socio-economic factors.</p><p><strong>Methods: </strong>Right eye data from eight Scottish health boards (HB) are reported for spherical equivalent refraction (SER) for the years 2013-14, 2014-15, 2015-16, 2020-21 and 2021-22. Associations were investigated between the proportion of the sample in each HB with myopia and the proportion of the population in each HB with different levels of deprivation index, classification on a rural/urban continuum and dwelling type.</p><p><strong>Results: </strong>Refractive error frequency distributions revealed a myopic shift in SER over the 5 years. Median SER (interquartile range) in 2013-14, 2014-15, 2015-16, 2020-21 and 2021-22 was +1.38 D (+0.50 to +2.75), +1.38 D (+0.25 to +2.63), +1.38 D (+0.50 to +2.75), +1.13 D (+0.25 to +2.25) and +1.25 D (+0.38 to +2.25), respectively. The increase in myopia was statistically significant in each of the last 2 years compared with each of the first 3 years (p < 0.0005). The proportion of myopes (≤-0.50 D) increased from <7.8% annually in 2013-16 to 11.51% in 2020-21 and 10.65% in 2021-22 (linear trend: r<sup>2</sup> = 0.94, p = 0.006). Associations between the proportion of children in each HB with myopia and: (1) deprivation index was low and not statistically significant; (2) the proportion of the population in the most urban environments was high (r<sup>2</sup> = 0.79; p = 0.003); (3) the proportion of dwellings that were flats/apartments was also high (r<sup>2</sup> = 0.83, p = 0.002).</p><p><strong>Conclusions: </strong>In this predominantly Caucasian population, the proportion of children with myopia has increased post-COVID. A strong association exists between myopia and living in flats/apartments and urbanicity, but not with a deprivation index.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"834-844"},"PeriodicalIF":2.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential impact of 0.01% and 0.05% atropine eye drops on visual performance in young adults. 0.01%和0.05%阿托品滴眼液对年轻人视力的不同影响。
IF 2.8 3区 医学
Ophthalmic and Physiological Optics Pub Date : 2025-05-01 Epub Date: 2025-02-20 DOI: 10.1111/opo.13471
Yifan Luo, Ziang Yin, Jiali Zhang, Zaifeng Cui, Yingying Huang, Xue Li, Hao Chen, Fan Lu, Jinhua Bao
{"title":"Differential impact of 0.01% and 0.05% atropine eye drops on visual performance in young adults.","authors":"Yifan Luo, Ziang Yin, Jiali Zhang, Zaifeng Cui, Yingying Huang, Xue Li, Hao Chen, Fan Lu, Jinhua Bao","doi":"10.1111/opo.13471","DOIUrl":"10.1111/opo.13471","url":null,"abstract":"<p><strong>Purpose: </strong>The onset and progression of myopia can occur during adulthood, suggesting that myopia should be managed in young adults. Low-concentration atropine eye drops have shown promising efficacy in myopia control. This study aimed to evaluate the impact of 0.01% and 0.05% atropine eye drops on the visual performance of university students.</p><p><strong>Methods: </strong>Twenty-six myopic students aged 18-30 years received 0.01% and 0.05% atropine in random order. Atropine eye drops were administered once a night in both eyes for 14 days, with a minimum 14-day washout period between concentrations. Visual assessments, including the modulation transfer function (MTF) cut-off, Strehl ratio (SR), objective scattering index, contrast sensitivity (CS) and glare disability, were conducted 1, 2, 7 and 14 days after atropine administration and corresponding time points after cessation. A questionnaire was used to evaluate ocular and general symptoms.</p><p><strong>Results: </strong>After 1 day of treatment with 0.05% atropine, the MTF cut-off (β = -8.75, p < 0.001) and SR (β = -0.05, p < 0.001) decreased significantly to their lowest levels. The area under the log CS function also decreased significantly (all p < 0.05) during administration of the 0.05% eye drops, especially in the mesopic with glare condition, and reached its lowest point 1 day after administration (β = -0.20, p < 0.001). However, all parameters returned to baseline levels 2 weeks after 0.05% atropine was stopped (all p > 0.05). Additionally, 40.91% of the young adults reported experiencing excessive daytime sleepiness and nocturnal glare during 0.05% atropine use. Treatment with 0.01% atropine had minimal effects on both visual performance and subjective symptoms.</p><p><strong>Conclusions: </strong>Administration of 0.05% atropine had a significant but temporary effect on the visual performance of young adult myopic patients, whereas 0.01% atropine had a minimal effect.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"854-864"},"PeriodicalIF":2.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measuring the effects of age on foveal surround suppression of contrast. 测量年龄对中央凹周围对比度抑制的影响。
IF 2.8 3区 医学
Ophthalmic and Physiological Optics Pub Date : 2025-05-01 Epub Date: 2025-03-17 DOI: 10.1111/opo.13488
Martin T W Scott, Alex R Wade, Heidi A Baseler
{"title":"Measuring the effects of age on foveal surround suppression of contrast.","authors":"Martin T W Scott, Alex R Wade, Heidi A Baseler","doi":"10.1111/opo.13488","DOIUrl":"10.1111/opo.13488","url":null,"abstract":"<p><strong>Purpose: </strong>The apparent contrast of a visible central grating can be reduced by the presence of a surrounding grating-an effect known as surround suppression of contrast. Surround suppression is strong when the orientation of the surround matches that of the central probe and is strongest in the periphery. There is evidence that surround suppression at the fovea increases in strength with age, and that the orientation dependence of surround suppression is weakened. However, the range of visual stimuli that can produce this effect (and the implicated underlying mechanisms) requires further examination. This study aimed to characterise surround suppression at the fovea and its dependence on age. Visual stimuli with previously unexplored spatiotemporal parameters were used, designed to minimise contributions from spatially short-range overlay masking and temporally transient masking mechanisms.</p><p><strong>Methods: </strong>In 20 younger (<30 years) and 17 older (>60 years) observers, psychophysical contrast-matching thresholds were measured using stimuli centred on the fovea. Grating stimuli were presented with either no surround, a collinearly oriented surround or an orthogonally oriented surround. Using a staircase procedure, observers matched the contrast of these central target stimuli to the contrast of a separate reference stimulus. The points of subjective equality between target and reference stimuli were compared between the two surround orientations and between younger and older age groups.</p><p><strong>Results: </strong>Across all observers, weak foveal surround suppression was found that had little orientation tuning. No evidence for the strength of surround suppression increasing with age is reported.</p><p><strong>Conclusions: </strong>These findings suggest that the age-related effects of surround suppression may be dependent on the spatiotemporal parameters of the stimulus used and encourage further exploration of the contrast masking mechanisms affected by age. The mild and weakly orientation-tuned suppression may have been produced by a weak and temporally sustained suppression mechanism.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"644-655"},"PeriodicalIF":2.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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