Ophthalmic and Physiological Optics最新文献

{"title":"Factors associated with myopia in the Portuguese child population: An epidemiological study.","authors":"Miguel Ángel Sánchez-Tena, Clara Martinez-Perez, Cristina Andreu-Vázquez, Ana Roque, Cristina Alvarez-Peregrina","doi":"10.1111/opo.13429","DOIUrl":"10.1111/opo.13429","url":null,"abstract":"<p><strong>Purpose: </strong>Myopia, a leading cause of correctable visual impairment, is projected to affect nearly 50% of the global population by 2050, posing a significant public health challenge. Understanding its prevalence and associated factors, particularly in children, is crucial for devising prevention and intervention strategies. This study aims to determine the proportion of myopia in school-aged children in Portugal and to examine the correlation between myopia occurrence and various environmental and genetic factors.</p><p><strong>Methods: </strong>A cross-sectional epidemiological study was conducted on children aged from 5 to 17 years from nine schools in Lisbon, Portugal, between September 2020 and May 2021. It included optometric assessments to evaluate refractive status and binocular vision, as well as questionnaires about their lifestyles and parental myopia.</p><p><strong>Results: </strong>Out of 1992 participants enrolled, 12.7% of the children were found to be myopic. The proportion of myopia increased with age and was higher in girls. A significant association was observed between myopia and parental history, with the likelihood being higher if one or both parents were myopic. Engaging in outdoor activities was associated with a lower likelihood of myopia.</p><p><strong>Conclusions: </strong>The study found that 12.7% of the children in the study sample, aged 5-17 years, were myopic, indicating a significant association with familial history and limited outdoor activities. These insights highlight the need for targeted myopia screening and prevention strategies in the paediatric population.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"542-549"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11823377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scleral lens wear and fluid reservoir turbidity in eyes with ocular surface disorders.","authors":"Vigneshwar A Goppalakrishnan, Bhaskar Srinivasan, Geetha Iyer, Asif Iqbal","doi":"10.1111/opo.13442","DOIUrl":"10.1111/opo.13442","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate changes in fluid reservoir turbidity parameters over time and its influence on visual performance in eyes with ocular surface disorders (OSD) wearing scleral contact lenses (SL).</p><p><strong>Methods: </strong>Thirteen eyes with OSD were assessed for corrected distance visual acuity, contrast sensitivity (CS) and fluid reservoir turbidity using anterior segment optical coherence tomography at baseline, after 5 min and 0.5, 1, 2, 3 and 4 h of SL wear on day 1 and after 1 month.</p><p><strong>Results: </strong>A significant reduction in CS was noted at 0.5, 1, 2, 3 and 4 h of SL wear compared to 5 min (p < 0.001) and a similar trend was noted after 1 month (p < 0.001). The average number of particles on day 1 showed a significant increase over 4 h of SL wear (p < 0.001), with a same trend noted at 1 month (p = 0.001). However, the percentage of particles decreased from 88% ± 4% to 75% ± 12% (p = 0.004) after 1 month of SL wear. Average particle size showed a significant increase at all time points over 4 h compared with 5 min of SL wear (p < 0.003) and after 1 month (p < 0.001). The percentage of average particle size decreased from 73% ± 9% to 67% ± 8% after 1 month of lens wear (p = 0.003). The mean percentage turbid area increased from 0.6% ± 0.5% to 24% ± 16% over 4 h of lens wear on day 1 (p < 0.006) and from 0.7% ± 0.5% to 11% ± 8% at 1 month (p = 0.001). The mean difference in percentage turbid area at the first and follow-up visits decreased from 96% ± 3% to 89% ± 9% (p = 0.01).</p><p><strong>Conclusions: </strong>A gradual increase in fluid reservoir turbidity parameters was noted with the reduction in CS; however, all these parameters improved after 1 month of SL wear.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"423-432"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142951960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractive error maps: A predictive tool for refractive error progression.","authors":"Fabian Debowy, Barbara Pierscionek","doi":"10.1111/opo.13444","DOIUrl":"10.1111/opo.13444","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the influence of axial length on different ocular parameters and create a predictive tool for refractive error progression.</p><p><strong>Methods: </strong>Two eye models were used to simulate refractive errors, namely the Liou-Brennan and the Goncharov-Dainty. Both models were simulated using Zemax OpticStudio. Simulations were made by varying axial length and central corneal radii of curvature, with values ranging from 21.5 to 28.5 mm and 7.0 to 8.5 mm, respectively. Additionally, simulations of different lens parameters were included.</p><p><strong>Results: </strong>Refractive error maps were produced for different ethnicities and a comparison with experimental results was undertaken. These showed the relationships between axial length and crystalline lens thickness, refractive index and curvatures of the cornea and lens.</p><p><strong>Conclusions: </strong>The concept of refractive error maps may provide more insight into the refractive state of individuals and groups with provision for a comparative analysis. With further experimental data added, such refractive error maps could be used as a predictive tool.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"577-588"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11823400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanism of optical treatments for myopia: Are lenslets joining the DOTs?","authors":"Jeremy A Guggenheim, Louise Terry","doi":"10.1111/opo.13426","DOIUrl":"10.1111/opo.13426","url":null,"abstract":"","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"337-339"},"PeriodicalIF":2.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The International Myopia Institute (IMI) and consensus building.","authors":"Nina Tahhan, Christine Wildsoet, Weizhong Lan, Serge Resnikoff","doi":"10.1111/opo.13458","DOIUrl":"10.1111/opo.13458","url":null,"abstract":"","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-population validation of the PreMO risk indicator for predicting myopia onset in children.","authors":"Jane M Fulton, Tsz Wing Leung, Sara J McCullough, Kathryn J Saunders, Nicola S Logan, Carly S Y Lam, Lesley Doyle","doi":"10.1111/opo.13416","DOIUrl":"10.1111/opo.13416","url":null,"abstract":"<p><strong>Purpose: </strong>The Predicting Myopia Onset and progression (PreMO) risk indicator, developed using data generated from white children in the UK, incorporates age, spherical equivalent refraction (SER), axial length (AL) and parental myopia to stratify the likelihood of developing myopia. This study evaluated the PreMO's predictive accuracy using prospective datasets from independent samples of children in Hong Kong (HK) and an ethnically diverse cohort of children in the United Kingdom.</p><p><strong>Methods: </strong>Non-myopic children (SER > -0.50 D) aged 6-8 and 9-10 years were scored using the PreMO risk indicator framework, integrating baseline cycloplegic SER, AL and parental myopia data. Scores were assigned risk categories as follows: 0 = no risk, 1-3 = low risk, 4-6 = moderate risk and 7-9 = high risk. SER at ≥15 years of age was used to define refractive outcomes as 'myopic' or 'not myopic'. PreMO's predictive accuracy was analysed via Receiver Operator Characteristic curves, with Youden's J-Index identifying the optimal risk score threshold. Sensitivity, specificity and area under the curve were determined and compared with those of singular predictors, that is, SER < +0.75 D and AL ≥ 23.07 mm at 6-8 years.</p><p><strong>Results: </strong>In the cohort of children aged 6-8 years, a PreMO risk score ≥ 4 exhibited high sensitivity in predicting myopia onset in UK (0.97) and HK (0.94) children, with high specificity in UK (0.96) and moderate specificity in HK (0.64) children. In UK children aged 6-8 years, the PreMO outperformed singular predictors such as SER and AL. Among HK children aged 9-10 years, the PreMO score maintained high sensitivity (0.90) and moderate specificity (0.72).</p><p><strong>Conclusions: </strong>A PreMO risk score ≥ 4 is a strong predictive indicator for future myopia onset, particularly in UK children. Despite high sensitivity in both UK and HK cohorts, specificity varied, indicating the need for contextual application of the tool, particularly in pre-myopic Asian children.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"89-99"},"PeriodicalIF":2.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myopia control strategies: A systematic review and meta-meta-analysis.","authors":"Ebenezer Zaabaar, Randy Asiamah, Samuel Kyei, Samuel Ankamah","doi":"10.1111/opo.13417","DOIUrl":"10.1111/opo.13417","url":null,"abstract":"<p><strong>Purpose: </strong>To summarise pooled estimates of the efficacies of various myopia control interventions, as drawn from published meta-analyses.</p><p><strong>Method: </strong>PubMed, SCOPUS and Web of Science were searched from inception to February 2024 for systematic reviews and meta-analyses reporting treatment effects of various myopia control strategies. The qualities of the included meta-analyses were assessed using the 16-item A MeaSurement Tool to Assess systematic Reviews (AMSTAR) 2. An intervention was defined as having a clinically significant effect if it resulted in a change in spherical equivalent refraction (SER) of ≥0.50 D/year or axial length (AL) change of ≤-0.18 mm/year.</p><p><strong>Results: </strong>A total of 38 studies were identified. The overall respective changes in SER and AL, mean difference (95% CI) were high-concentration (≥0.5%) atropine 0.67 D (0.58-0.77) and -0.24 mm (-0.36 to -0.11); moderate-concentration (>0.05% to <0.5%) atropine 0.48 D (0.34-0.62) and -0.23 mm (-0.27 to -0.19); low-concentration (0.01%, 0.025%, 0.05%) atropine 0.33 D (0.23-0.43) and -0.14 mm (-0.19 to -0.09); orthokeratology -0.47 mm (-0.66 to -0.28); peripheral plus soft contact lenses 0.30 D (0.18-0.42) and -0.35 mm (-0.62 to -0.08); peripheral plus spectacles 0.77 D (0.40-1.14) and -0.43 mm (-0.78 to -0.08); multifocal spectacles 0.21 D (0.11-0.31); repeated low-level red light therapy 0.55 D (0.46-0.65) and -0.25 mm (-0.29 to -0.20); outdoor time 0.17 D (0.16-0.18) and -0.04 mm (-0.06 to -0.01).</p><p><strong>Conclusion: </strong>High and moderate concentrations of atropine, orthokeratology, peripheral plus spectacles and repeated low-level red light demonstrated clinically significant effects on slowing AL elongation, while high and moderate concentrations of atropine, peripheral plus spectacles and repeated low-level red light demonstrated clinically significant effects on slowing SER progression.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"160-176"},"PeriodicalIF":2.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142624634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deprivation and NHS General Ophthalmic Service sight testing activity in England in 2022-2023.","authors":"Robert A Harper, Jeremy Hooper, David J Parkins, Cecilia H Fenerty, James Roach, Michael Bowen","doi":"10.1111/opo.13399","DOIUrl":"10.1111/opo.13399","url":null,"abstract":"<p><strong>Purpose: </strong>Socioeconomic deprivation is associated with an increased incidence of sight-loss. To inform potential developments in eyecare, General Ophthalmic Service (GOS) sight-testing activity was explored in relation to deprivation for GOS contractors submitting National Health Service (NHS) claims in England.</p><p><strong>Methods: </strong>Data on NHS sight-test claims for the financial year 2022-2023 were sought from NHS England (NHSE), including number of sight-tests by GOS contractors, their unique Organisation Data Service codes and postcodes and age-bands of patients accessing sight-testing. Deprivation scores were assigned to contractor practices using the Index of Multiple Deprivation (IMD) and the average number of sight-tests for all contractors within each IMD decile calculated, allowing rate of sight-testing per 1000 population per decile of deprivation to be estimated using Office of National Statistics (ONS) Lower Layer Super Output Area mid-year population estimates. Inequality was examined using the Odds Ratio (OR) and slope and relative index of inequality measures (SSI and RII).</p><p><strong>Results: </strong>Overall, 12.94 million NHS sight-tests were provided by 5622 GOS contractors in England in 2022-2023. Most affluent decile GOS contractors undertook an average ~2200 NHS sight-tests, while in the most deprived decile, average NHS sight-tests per contractor was ~1100. Rate of sight-testing per 1000 population in the most deprived decile was one quarter of that in the most affluent, with an OR of 5.29 (95% CI 5.27-5.30), indicating those in the most affluent areas were ~five times more likely to access NHS sight-tests. Overall, SII and RII were 333.5 (95% CI 333.52-333.53) and 6.4 (95% CI 6.39-6.40), respectively, findings reflective of substantial inequality in uptake.</p><p><strong>Conclusion: </strong>There remains substantial unwarranted variation in uptake of NHS sight-testing, with those in more affluent areas accessing sight-testing substantially more than those in more deprived areas. Strategies are required to facilitate primary care optometry to provide more equitable access to eyecare.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"294-300"},"PeriodicalIF":2.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142392130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classification of accommodative insufficiency by monocular subjective push-up test is poorly predictive of monocular objective amplitudes in children and young adults.","authors":"Heather A Anderson, Sidney M Parks, Marjean T Kulp, G Lynn Mitchell","doi":"10.1111/opo.13419","DOIUrl":"10.1111/opo.13419","url":null,"abstract":"<p><strong>Introduction: </strong>To determine whether classification of accommodative insufficiency (AI) based on the subjective push-up test is indicative of reduced amplitude measured objectively.</p><p><strong>Methods: </strong>Monocular subjective accommodative amplitude was measured in participants 7-24 years of age with the push-up test; a 0.9 mm letter was moved towards the eye until first sustained blur occurred. Monocular objective amplitude was measured with the same target and an autorefractor for demands from 2.5 to 30 D. The maximum response was termed the amplitude. Near point of convergence (NPC) was measured in a subset of participants. Participants were classified into groups using subjective amplitude: normal amplitude or AI (amplitude < ((15 - 0.25 × age) - 2)). Objective amplitude was plotted by age for each group and one-way ANCOVA used to evaluate differences while controlling for age. For NPC measures, a t-test compared the magnitude of the break between those with and without AI.</p><p><strong>Results: </strong>Fifty-five of 185 participants were classified as having AI. Objective amplitude decreased with age (0.20 D/year) and there was no significant difference in the age-adjusted mean amplitudes for the two groups (AI: 7.62 D, CI = 7.19, 8.04; Normal: 7.86 D, CI = 7.58, 8.15; p = 0.11). For the subset with NPC measures, participants classified as having AI had significantly more receded break values than those without AI (7.7 ± 5 vs. 3.7 ± 3 cm, p < 0.001).</p><p><strong>Conclusions: </strong>Factors other than accommodative ability may be contributing to lower subjective amplitude findings in individuals meeting the criterion for AI.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"14-22"},"PeriodicalIF":2.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accommodative behaviour and retinal defocus in highly myopic eyes fitted with a dual focus myopia control contact lens.","authors":"Dawn Meyer, Javier Gantes-Nuñez, Martin Rickert, Nitya Murthy, Paul Chamberlain, Arthur Bradley, Pete Kollbaum","doi":"10.1111/opo.13420","DOIUrl":"10.1111/opo.13420","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the myopic and hyperopic defocus delivered to the retina by a dual focus (DF) myopia control contact lens when myopia exceeds 6.00 D.</p><p><strong>Methods: </strong>Individuals with high myopia were fitted bilaterally with high-powered DF lenses containing power profiles matching a Coopervision MiSight 1 day contact lens (omafilcon A) and a Coopervision Proclear 1 day single vision (SV) lens. Wavefront measurements along the primary line of sight and across the central ±20° of the horizontal retina were acquired using a pyramidal aberrometer, while subjects accommodated to high-contrast letter stimuli (6/12 equivalent) at six target vergences (-0.25 and -1.00 to -5.00 D). Linear mixed-effects regression models explored the relationship between the spherical equivalent refractive error (SERE) and induced defocus.</p><p><strong>Results: </strong>Thirteen teenagers and young adults (ages 13-32 years, mean [standard deviation, SD] age = 22.8 [4.9] years) with high myopia (SERE -6.50 to -9.25 D) were tested. The treatment optic zone of the DF lens shifted retinal defocus by the expected -2.00 D, with a mean (SD) difference (DF-SV) of -2.21 (0.18) D for the inner treatment ring. Inclusion of the treatment optic had no significant impact on accommodative accuracy (p = 0.51). Accommodative lags were larger at the nearer viewing distances, with lag increasing by approximately 0.30 D for every additional dioptre of SERE. Measured retinal defocus within the annular treatment zone was approximately -2.00 D at the foveal centre, 10° nasal and temporal and 20° nasal and reduced to -1.90 (0.57) D at 20° temporal.</p><p><strong>Conclusions: </strong>Relative to eyes with lower levels of myopia, the increased accommodative lags and more prolate retinas of highly myopic eyes reduced the myopic retinal defocus from the DF myopia control lens, while the treatment optical zones generated the combined effect of reducing hyperopic and introducing myopic retinal defocus relative to an SV correction.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"189-199"},"PeriodicalIF":2.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11629841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}