Ophthalmology. Retina最新文献

{"title":"Curvilinear Vitreous Humor Strands in Hereditary Transthyretin Amyloidosis","authors":"Zehao Liu MD, Jinli Cui MD, Ying Lin MD, PhD","doi":"10.1016/j.oret.2024.12.001","DOIUrl":"10.1016/j.oret.2024.12.001","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 7","pages":"Page e75"},"PeriodicalIF":4.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OCT of Multilobulated Ocular Cysticercosis","authors":"Rohan Kapoor MS, Mudit Tyagi MS","doi":"10.1016/j.oret.2024.11.008","DOIUrl":"10.1016/j.oret.2024.11.008","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 7","pages":"Page e70"},"PeriodicalIF":4.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Surgical Competency among Fellows in Vitreoretinal Surgery","authors":"Muhammad Hassan MD ,&nbsp;Kapil Mishra MD ,&nbsp;Linus Amarikwa MD ,&nbsp;Omesh P. Gupta MD ,&nbsp;Sunil Srivastava MD ,&nbsp;Adrienne W. Scott MD ,&nbsp;Philip J. Ferrone MD ,&nbsp;Yannek I. Leiderman MD, PhD ,&nbsp;Prithvi Mruthyunjaya MD, MHS","doi":"10.1016/j.oret.2025.01.008","DOIUrl":"10.1016/j.oret.2025.01.008","url":null,"abstract":"<div><h3>Purpose</h3><div>We surveyed vitreoretinal (VR) fellowship program directors (PDs) to elucidate how they assess surgical competency among VR fellows. In addition, we also surveyed fellowship program graduates for the years 2022 and 2023 regarding assessment metrics and tools used during VR fellowship training.</div></div><div><h3>Design</h3><div>Web-based, cross-sectional descriptive study.</div></div><div><h3>Subjects</h3><div>Fellowship PDs and recent fellowship graduates in the United States and Canada</div></div><div><h3>Methods</h3><div>The survey, distributed via email, queried participants about several aspects of assessing surgical competency in VR training including surgical numbers, teaching/assessment methods used to assess fellow surgical competency, comfort of fellows for various surgical procedures, appropriate degree of supervision, and criteria for a hypothetical national competence standard. A Likert scale was utilized for questions capturing participants’ opinion. Mean response scores were reported.</div></div><div><h3>Main Outcome Measures</h3><div>Comparison of responses between PDs and fellows.</div></div><div><h3>Results</h3><div>Forty-two PDs (42.1%) (33 university-based and 9 private institutions) and 40 fellows (16.8%) (28 academic and 12 private institutions) responded to the survey. Fellows expect a higher minimum number of vitrectomies (≥300) by graduation than PDs (≥200). Both PDs and fellows ranked direct observation of fellow (4.95/4.75), discussion with other faculty on fellow surgical performance (3.93/3.60), and outcomes of fellow surgical cases (3.88/3.53) (<em>P</em> &gt; 0.05) respectively, as top 3 teaching tools. Both PDs and fellows expressed high comfort levels with various complex surgeries, such as primary scleral buckle (4.45/4.60), proliferative vitreoretinopathy detachments (4.57/4.45), advanced diabetic retinal detachments (4.57/4.38), and giant retinal tears (4.64/4.50), by the time of graduation. Autonomy was also considered an important indicator of surgical competence by both groups. However, apart from direct surgical experience, fellows rated other educational tools lower than PDs. There was overall agreement between the groups on several aspects of a hypothetical national competence standard.</div></div><div><h3>Conclusions</h3><div>This survey identified that the key tools utilized to assess surgical proficiency were direct observation of surgery by attending physician, discussions about fellow performance among faculty, and outcomes of fellow surgical cases. Both groups emphasized that by graduation, fellows should be proficient in several complex VR surgeries. These findings suggest a need for a more systematic approach to assess surgical competency of VR fellows.</div></div><div><h3>Financial Disclosure(s)</h3><div>Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.</div></div>","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 7","pages":"Pages 699-708"},"PeriodicalIF":4.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Follow-up Algorithm after Bevacizumab Treatment for Retinopathy of Prematurity","authors":"Maram Isaac MBBS, MHA ,&nbsp;Kamiar Mireskandari FRCOphth, PhD ,&nbsp;Peter J. Kertes MDCM, FRCSC ,&nbsp;Nasrin N. Tehrani MBChB, FRCSC","doi":"10.1016/j.oret.2025.02.010","DOIUrl":"10.1016/j.oret.2025.02.010","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 7","pages":"Pages 709-711"},"PeriodicalIF":4.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Griffin et al.: Pneumatic retinopexy for rhegmatogenous retinal detachment outcomes: IRIS® Registry (Intelligent Research in Sight) analysis (Ophthalmol Retina. 2025;9:437-443)","authors":"Fernando J. Huelin MD, MSc ,&nbsp;Peter J. Kertes MD CM ,&nbsp;Roxane J. Hillier MBChB, FRCOphth","doi":"10.1016/j.oret.2025.04.012","DOIUrl":"10.1016/j.oret.2025.04.012","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 7","pages":"Pages e63-e64"},"PeriodicalIF":4.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eroded Gore-Tex Scleral Sutures and Endophthalmitis in Atopic Keratoconjunctivitis","authors":"Joseph Colcombe MD ,&nbsp;Leela Raju MD ,&nbsp;Yasha Modi MD","doi":"10.1016/j.oret.2024.11.001","DOIUrl":"10.1016/j.oret.2024.11.001","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 7","pages":"Page e69"},"PeriodicalIF":4.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"End-Stage PRPH2-associated Retinopathy Presenting with Macular Caldera","authors":"Andrea Trinco MD ,&nbsp;Giovanni Staurenghi MD ,&nbsp;Francesco Romano MD","doi":"10.1016/j.oret.2024.10.024","DOIUrl":"10.1016/j.oret.2024.10.024","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 7","pages":"Pages e66-e67"},"PeriodicalIF":4.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tattoo-associated Uveitis in Sarcoidosis","authors":"Elaine Hu ,&nbsp;Travis Vandergriff MD ,&nbsp;Jennifer H. Cao MD","doi":"10.1016/j.oret.2024.11.009","DOIUrl":"10.1016/j.oret.2024.11.009","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 7","pages":"Pages e71-e72"},"PeriodicalIF":4.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomic Control with Faricimab versus Aflibercept in the YOSEMITE/RHINE Trials in Diabetic Macular Edema","authors":"Jennifer I. Lim MD ,&nbsp;Manuel J. Amador MD ,&nbsp;Dilsher S. Dhoot MD ,&nbsp;Avni Finn MD, MBA ,&nbsp;Samantha Fraser-Bell MBBS, PhD ,&nbsp;Kara Gibson PhD ,&nbsp;Oluwatobi O. Idowu MD, MBA ,&nbsp;Rahul N. Khurana MD ,&nbsp;Paolo Lanzetta MD ,&nbsp;Tai-Chi Lin MD, PhD ,&nbsp;Florie A. Mar PhD ,&nbsp;Andreas Pollreisz MD ,&nbsp;Aleksandra Rachitskaya MD ,&nbsp;Patricio G. Schlottmann MD ,&nbsp;Yannan Tang PhD ,&nbsp;Timothy Y.Y. Lai MD","doi":"10.1016/j.oret.2025.01.017","DOIUrl":"10.1016/j.oret.2025.01.017","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare anatomic biomarkers on spectral-domain OCT between faricimab, a dual angiopoietin-2 (Ang-2)/VEGF-A inhibitor, and aflibercept in a pooled analysis of results from the YOSEMITE/RHINE trials in diabetic macular edema (DME).</div></div><div><h3>Design</h3><div>YOSEMITE/RHINE (NCT03622580/NCT03622593) were identical, randomized, double-masked, active comparator-controlled, 100-week phase III noninferiority trials.</div></div><div><h3>Participants</h3><div>Adults with visual acuity loss due to center-involving DME.</div></div><div><h3>Methods</h3><div>Patients were randomized 1:1:1 to faricimab 6.0 mg every 8 weeks (Q8W), faricimab 6.0 mg treat-and-extend (T&amp;E), or aflibercept 2.0 mg Q8W for 100 weeks. The T&amp;E up to every 16 weeks dosing regimen was based on central subfield thickness (CST) and best-corrected visual acuity changes.</div></div><div><h3>Main Outcome Measures</h3><div>Post hoc analyses comparing faricimab with aflibercept on CST change; the proportion of eyes with an absence of intraretinal fluid (IRF), subretinal fluid, or both IRF and subretinal fluid or achieving a CST &lt;280 μm at key timepoints during the trials; time to first absence of IRF; and time to first achieving CST &lt;280 μm.</div></div><div><h3>Results</h3><div>In total, 1891 patients were enrolled across YOSEMITE/RHINE (n = 632 faricimab Q8W; n = 632 faricimab T&amp;E; n = 627 aflibercept). There were greater CST reductions from baseline with both faricimab dosing regimens compared with aflibercept over the 100 weeks (adjusted means and area-under-the-curve analysis). Higher proportions of eyes achieved an absence of IRF with faricimab Q8W (58%–63%) and faricimab T&amp;E (44%–49%) versus aflibercept (36%–41%) at weeks 92 to 100. In eyes with IRF at baseline, the median time to first absence of IRF was achieved 40 weeks earlier with faricimab versus aflibercept. The proportion of eyes achieving a CST &lt;280 μm at weeks 92 to 100 was 70% to 74% with faricimab Q8W, 61% to 65% with faricimab T&amp;E, and 61% to 63% with aflibercept. In eyes with CST ≥280 μm at baseline, the median time to first instance of CST &lt;280 μm was achieved 16 weeks earlier with faricimab versus aflibercept.</div></div><div><h3>Conclusions</h3><div>Dual Ang-2/VEGF-A inhibition with faricimab resulted in greater and faster improvements in anatomic outcomes compared with aflibercept at key timepoints over the pooled YOSEMITE/RHINE trials.</div></div><div><h3>Financial Disclosure(s)</h3><div>Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.</div></div>","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 7","pages":"Pages 655-666"},"PeriodicalIF":4.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vessels Spanning Avascular Retina in Familial Exudative Vitreoretinopathy","authors":"David Wade Redick MD,&nbsp;Joshua M. Barnett MD, PhD,&nbsp;George Baker Hubbard III MD","doi":"10.1016/j.oret.2025.02.022","DOIUrl":"10.1016/j.oret.2025.02.022","url":null,"abstract":"","PeriodicalId":19501,"journal":{"name":"Ophthalmology. Retina","volume":"9 7","pages":"Pages 711-712"},"PeriodicalIF":4.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}