NutritionPub Date : 2026-03-17DOI: 10.1016/j.nut.2026.113217
Kathula Jaya Angel, Anamika Shaji, P Mohammad Shuaib
{"title":"Comment on \"The associations between dairy product and egg intake and NAFLD remission: Evidence from a prospective cohort study\".","authors":"Kathula Jaya Angel, Anamika Shaji, P Mohammad Shuaib","doi":"10.1016/j.nut.2026.113217","DOIUrl":"https://doi.org/10.1016/j.nut.2026.113217","url":null,"abstract":"","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":" ","pages":"113217"},"PeriodicalIF":3.6,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148930765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Mediterranean Diet for the primary prevention of autoimmune diseases: A systematic review and meta-analysis featured in the Italian National Guidelines “La Dieta Mediterranea”","authors":"Vincenza Gianfredi M.D., Ph.D. , Letizia Baldini M.D. , Andrea Deledda Ph.D. , Maria Michela Patruno M.D. , Lucia Galluzzo M.A. , Fernanda Velluzzi M.D. , Domenico Rogoli M.Sc. , Filippo Valoriani M.D. , Nicola Veronese M.D. , Massimo Volpe M.D. , Stefania Maggi M.D. , Graziano Onder M.D., Ph.D. , Marco Silano M.D. , Michela Zanetti M.D. , Daniele Nucci M.Sc., R.D. , Mediterranean Diet Guideline Group","doi":"10.1016/j.nut.2025.113013","DOIUrl":"10.1016/j.nut.2025.113013","url":null,"abstract":"<div><div>The Mediterranean Diet (MD) has been associated with reduced inflammation and improved immune regulation, suggesting a potential protective role against autoimmune diseases. This review was conducted in accordance with PRISMA 2020 and MOOSE guidelines. A comprehensive search of PubMed/MEDLINE, Scopus, Embase, and Cochrane Library was performed up to February 28, 2024. Study quality was assessed using the Newcastle–Ottawa Scale, and the certainty of evidence was evaluated with the NUTRIGRADE approach. Pooled effect sizes were computed using a random-effects model and expressed as risk ratios (RR), hazard ratios (HR), or odds ratios (OR), as appropriate. A total of 9 high-quality studies were included. No significant associations were found between high vs. low MD adherence and the incidence of rheumatoid arthritis (RR = 0.99, 95% CI: 0.97–1.01), lupus (HR = 0.97, 95% CI: 0.91–1.03), Crohn’s disease (RR = 0.95, 95% CI: 0.84–1.07), or ulcerative colitis (RR = 1.02, 95% CI: 0.97–1.08). A significant inverse association was observed for multiple sclerosis (RR = 0.91, 95% CI: 0.85–0.98) and for Sjögren’s syndrome (OR = 0.81, 95% CI: 0.66–0.99). However, the certainty of evidence for all outcomes was rated as low. Promising associations were observed for multiple sclerosis and Sjögren’s syndrome, although current evidence does not support a consistent protective effect of the MD across several other autoimmune diseases. Further longitudinal research is needed to confirm these findings and explore underlying mechanisms. Meanwhile, the promotion of MD adherence remains justified within broader public health strategies for chronic disease prevention.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"143 ","pages":"Article 113013"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145594483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Severe copper deficiency–related polyneuropathy following laparoscopic sleeve gastrectomy: A case report and literature review","authors":"Yu-Hao Huang M.D. , Mei-Chuan Chou M.D., M.Sc. , Jih-Jin Tsai M.D., Ph.D.","doi":"10.1016/j.nut.2025.113036","DOIUrl":"10.1016/j.nut.2025.113036","url":null,"abstract":"<div><h3>Background</h3><div>Sleeve gastrectomy (SG) has become the most commonly performed bariatric procedure due to its favorable weight-loss outcomes and lower complication risks. However, serious neurological complications can still occur. We present a case of severe copper deficiency–related polyneuropathy following SG in a 48-y-old man.</div></div><div><h3>Case Presentation</h3><div>A 48-y-old man underwent laparoscopic SG for morbid obesity. Three months postoperatively, he developed poor oral intake. At 7 mo, he presented with bilateral distal paresthesia and gait disturbance. Symptoms transiently improved after vitamin B supplementation but progressively worsened. At 9 mo, he was admitted with severe polyneuropathy. Laboratory testing revealed marked hypocupremia. Intravenous copper supplementation led to substantial neurological improvement, and he was eventually discharged with neurological improvement.</div></div><div><h3>Literature Review</h3><div>Four reports involving five cases of polyneuropathy due to copper deficiency after SG or Roux-en-Y gastric bypass were identified in a search of the literature. Additionally, incidence rates of neurological complications and copper deficiency following SG and Roux-en-Y gastric bypass were reviewed.</div></div><div><h3>Conclusions</h3><div>In this case report, we emphasize vigilance regarding the presence of copper deficiency after SG, demonstrate that timely supplementation improves outcomes, recommend laboratory evaluation when postoperative neurological symptoms occur, and highlight the need for standardized postoperative copper monitoring and dosing guidelines.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"143 ","pages":"Article 113036"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NutritionPub Date : 2026-03-01Epub Date: 2025-11-23DOI: 10.1016/j.nut.2025.113035
Núbia Maria Oliveira M.Sc. , Raquel Revuelta Iniesta Ph.D. , Dimitris Vlachopoulos Ph.D. , Alan R. Barker Ph.D. , Catarina Nunes Matias Ph.D. , Ezequiel Moreira Gonçalves Ph.D. , Eero A. Haapala Ph.D. , Timo A. Lakka Ph.D.
{"title":"Can regional phase angle reflect changes in physical fitness and body composition from late childhood to adolescence? A cohort study","authors":"Núbia Maria Oliveira M.Sc. , Raquel Revuelta Iniesta Ph.D. , Dimitris Vlachopoulos Ph.D. , Alan R. Barker Ph.D. , Catarina Nunes Matias Ph.D. , Ezequiel Moreira Gonçalves Ph.D. , Eero A. Haapala Ph.D. , Timo A. Lakka Ph.D.","doi":"10.1016/j.nut.2025.113035","DOIUrl":"10.1016/j.nut.2025.113035","url":null,"abstract":"<div><h3>Objectives</h3><div>It is unclear whether regional phase angle (R-PhA), measured by bioelectrical impedance (BIA), is associated with changes in physical fitness and body composition during growth. We examined longitudinal associations between R-PhA and these outcomes.</div></div><div><h3>Methods</h3><div>Two hundred seventy participants (122 girls) from the Physical Activity and Nutrition in Children (PANIC) study were analyzed at ages 9.7 ± 0.4 (T1) and 15.8 ± 0.4 years (T2). Multifrequency BIA provided R-PhA (arm, leg). Dual-energy X-ray absorptiometry (DXA) determined total lean mass (LM) and fat mass percentage (%FM). Handgrip strength (HS) and standing long jump (SLJ) were scaled by body mass. Peak oxygen uptake (VO₂<sub>peak</sub>) was measured using a cycle ergometer test and scaled by LM. Changes were calculated as T2–T1 (Δ). Regression models tested associations between Δ R-PhA and Δ outcomes (adjusted for pubertal status) and whether Δ R-PhA predicted T2 outcomes (adjusted for outcome, body composition, pubertal status, and moderate-to-vigorous physical activity at T1).</div></div><div><h3>Results</h3><div>ΔPhA-Arm was associated with ΔHS (β = 0.23 girls; β = 0.24 boys), ΔSLJ (β = 0.29; β = 0.38), ΔLM (β = 0.33; β = 0.45), and Δ%FM (β = −0.22 boys). ΔPhA-Leg was associated with ΔHS (β = 0.29 boys), ΔSLJ (β = 0.23; β = 0.25), ΔVO₂<sub>peak</sub> (β = 0.25 girls), ΔLM (β = 0.26; β = 0.59), and Δ%FM (β = 0.20; β = −0.24). At T2, ΔR-PhA positively predicted HS and SLJ in both sexes, LM in boys, and ΔPhA-Arm predicted LM in girls.</div></div><div><h3>Conclusions</h3><div>Increases in R-PhA were mainly related to gains in strength, power, and LM, indicating that PhA captures aspects of muscle function and composition. Nonetheless, its use for diagnostic or decision-making purposes remains to be clarified.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"143 ","pages":"Article 113035"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Associations of chronic obstructive pulmonary disease with sarcopenia and related factors: Nutritional status, body composition, antioxidant capacity, and inflammatory profile","authors":"Shih-Pin Chen M.D., Ph.D. , Jia-En Hsu M.Sc. , Yu-Chiao Wu M.Sc. , Ping-Ting Lin Ph.D.","doi":"10.1016/j.nut.2025.113016","DOIUrl":"10.1016/j.nut.2025.113016","url":null,"abstract":"<div><h3>Objectives</h3><div>The purpose of this study was to investigate the relationships of nutritional status with sarcopenia status, antioxidative capacity, inflammatory status, and adipomyokines levels in patients with chronic obstructive pulmonary disease (COPD).</div></div><div><h3>Methods</h3><div>This study was design as a case-control study. Participants with and without COPD were recruited. Body composition, muscle function, antioxidant capacity (coenzyme Q10, antioxidant enzymes activity, and total antioxidant capacity), inflammatory markers (high-sensitivity C-reactive protein and interleukin-6), and adipomyokines levels (adiponectin, leptin, and irisin) were measured. Nutritional status was assessed by means of the mini nutritional assessment (MNA) and nutritional risk index (NRI).</div></div><div><h3>Results</h3><div>A total of 112 participants were included in the present study (COPD, <em>n</em> = 51; non-COPD, <em>n</em> = 61). Compared with non-COPD patients, COPD patients had a lower level of muscle function and nutritional status and a greater risk of developing sarcopenia (<em>P</em> < 0.05). Thirty-seven percent of the COPD patients in this study suffered from sarcopenia. Although there was no significant difference in antioxidant capacity between the two groups, most participants had a low coenzyme Q10 status (<0.5 μM). Compared with non-COPD patients, COPD patients had a greater level of adiponectin but a lower level of leptin (<em>P</em> < 0.05). Nutrition status (MNA or NRI) was significantly associated with muscle function, antioxidant capacity, inflammatory status, adipomyokines levels, and the risk of developing COPD and sarcopenia (<em>P</em> < 0.05).</div></div><div><h3>Conclusions</h3><div>Patients with COPD were at risk for malnutrition and sarcopenia, and most participants had low coenzyme Q10 status. Nutritional status affects antioxidant and anti-inflammatory status; and is inversely associated to the risk of developing sarcopenia. Thus, we suggest that monitoring the nutritional and muscle status of COPD patients, particularly that of older patients, is urgently needed.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"143 ","pages":"Article 113016"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145682510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NutritionPub Date : 2026-03-01Epub Date: 2025-11-15DOI: 10.1016/j.nut.2025.113021
Julius Wu B.A. , Elka Jacobson-Dickman M.D., M.H.A.
{"title":"The impact of nutrition, exercise, and pharmacotherapy on menstrual health in adolescents with overweight and obesity","authors":"Julius Wu B.A. , Elka Jacobson-Dickman M.D., M.H.A.","doi":"10.1016/j.nut.2025.113021","DOIUrl":"10.1016/j.nut.2025.113021","url":null,"abstract":"<div><h3>Background</h3><div>Menstrual health is a critical marker of physiological and psychological well-being in adolescents. While undernutrition and energy deficiency are well-known causes of menstrual disruption through hypothalamic hypogonadal suppression, the impact of overweight and obesity on menstrual physiology is an increasing clinical concern as adolescent obesity rates continue to rise globally.</div></div><div><h3>Objectives</h3><div>This review synthesizes current evidence on how excess adiposity, diet quality, physical activity, insulin sensitizers, and weight-modifying medications affect menstrual health in adolescents through the complex interplay of metabolic fuel signaling and reproductive endocrine pathways.</div></div><div><h3>Methods</h3><div>We review the activity of the hypothalamic-pituitary-gonadal axis during pubertal development and the reproductive years, highlighting how metabolic signals, particularly leptin, insulin, and ghrelin, influence gonadotropin-releasing hormone secretion. We explore how excess adiposity may accelerate menarche, disrupt menstrual regularity, and increase the risk of polycystic ovary syndrome and hyperandrogenism, likely through hyperinsulinemia and altered gonadotropin-releasing hormone pulsatility. We also discuss the contributions of suboptimal diet quality and obesity to chronic inflammation and ovarian dysfunction.</div></div><div><h3>Results</h3><div>Structured lifestyle interventions, including dietary modifications and regular physical activity, remain the cornerstone of managing overweight-related menstrual irregularities, to restore cycle regularity, and improve features of polycystic ovary syndrome. Insulin sensitizers, such as metformin, offer additional benefits for both metabolic and reproductive dysfunction. Newer incretin-based therapies, including semaglutide and tirzepatide, show promise in achieving significant weight reduction and metabolic improvements, with potential downstream benefits for menstrual health. However, data on their safety, reproductive outcomes, and optimal use in adolescents remain limited, and this area of research is still emerging.</div></div><div><h3>Conclusions</h3><div>While underweight status and malnutrition are important underpinnings of functional hypothalamic amenorrhea, the rising prevalence of overweight and obesity poses a growing risk to menstrual health in adolescents. Early, comprehensive, and personalized strategies that integrate nutrition, physical activity, psychological support, and, when appropriate, insulin sensitizers and other pharmacotherapies can help protect and enhance reproductive endocrine function, preserve fertility, and mitigate long-term health risks. Further research is needed to clarify the impact and long-term effects of novel weight-loss medications in order to inform clinical practice in adolescent care.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"143 ","pages":"Article 113021"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145733783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NutritionPub Date : 2026-03-01Epub Date: 2025-11-02DOI: 10.1016/j.nut.2025.113007
Yuchan Yang M.D. , Feng Zhu M.D. , Qiong Wu M.D. , Jiansheng Wang M.D. , Xueni Qiu M.D. , Song Li M.D. , Yi Xu M.D. , Jianfeng Gong Ph.D.
{"title":"Efficacy of exclusive enteral nutrition as a salvage therapy in adults with Crohn’s disease refractory to biologic treatment","authors":"Yuchan Yang M.D. , Feng Zhu M.D. , Qiong Wu M.D. , Jiansheng Wang M.D. , Xueni Qiu M.D. , Song Li M.D. , Yi Xu M.D. , Jianfeng Gong Ph.D.","doi":"10.1016/j.nut.2025.113007","DOIUrl":"10.1016/j.nut.2025.113007","url":null,"abstract":"<div><h3>Objectives</h3><div>Exclusive enteral nutrition (EEN) is a well-established therapy for inducing remission in luminal Crohn’s disease (CD), but its role in biologic-refractory patients remains unclear. This study aimed to evaluate the efficacy of EEN in biologic-refractory CD in adults and identify factors influencing treatment outcomes.</div></div><div><h3>Methods</h3><div>A single-center retrospective study was conducted on adult CD patients who received EEN between January 2021 and December 2024. Patients with active disease despite prior biologic therapy were included, along with a biologic-naïve subgroup for comparison. Clinical and laboratory data were analyzed, and remission rates were compared, stratified by the number of failed biologics. Logistic regression identified predictors of EEN efficacy.</div></div><div><h3>Results</h3><div>Among 224 patients, 94 were biologics-refractory, and 130 were biologics-naïve. Clinical remission at week 6 was achieved in 63.8% of biologic-refractory versus 73.8% of biologic-naïve patients (<em>P</em> = 0.11). Remission rates in patients failing one or two biologics were similar to biologic-naïve patients, but were significantly lower in those failing more than three biologics (<em>P</em> < 0.01). Multivariate analysis identified gastrointestinal bleeding (OR = 0.08; 95% [CI] = [0.03–1.20], <em>P</em> = 0.03) and failure of more than three biologics (OR = 0.11; 95% [CI] = [0.02–0.50], <em>P</em> < 0.01) as independent risk factors for nonremission.</div></div><div><h3>Conclusions</h3><div>EEN is an effective salvage therapy for biologic-refractory CD in adults, but its efficacy diminishes with increased biologic failures. Additionally, active CD with gastrointestinal bleeding is associated with a lower likelihood of achieving clinical remission.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"143 ","pages":"Article 113007"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145682509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NutritionPub Date : 2026-03-01Epub Date: 2025-11-23DOI: 10.1016/j.nut.2025.113032
Yuqi Liu , Hanke Ma , Yin Lu , Donglin Jiang , Ling Liu , Yongjian Zhu , Yacong Bo , Peng Wang , Jianxiang Shi , Lin Shang , Chensu Yang , Hua Ye , Qiaozhen Cai
{"title":"Sweet Foods Intake and Risk of Pancreatic Diseases: A large cohort study from the UK Biobank","authors":"Yuqi Liu , Hanke Ma , Yin Lu , Donglin Jiang , Ling Liu , Yongjian Zhu , Yacong Bo , Peng Wang , Jianxiang Shi , Lin Shang , Chensu Yang , Hua Ye , Qiaozhen Cai","doi":"10.1016/j.nut.2025.113032","DOIUrl":"10.1016/j.nut.2025.113032","url":null,"abstract":"<div><h3>Objectives</h3><div>Growing evidence has linked sweet food intake to obesity, diabetes, and mortality, but its association with pancreatic disease remains underexplored.</div></div><div><h3>Methods</h3><div>A total of 136 367 participants aged 40–69 y from the UK Biobank were included. Sweet food intake was assessed through dietary questionnaires, and pancreatic disease outcomes were identified using clinical and self-reported data. Multivariable Cox proportional hazards regression models were employed to estimate the hazard ratios (HRs) for pancreatic disease risk across quartiles of sweet food intake.</div></div><div><h3>Results</h3><div>During a median (interquartile range) follow-up of 11.6 (11.2–12.4) y, 348 pancreatic cancer events, 527 acute pancreatitis events, and 319 chronic pancreatitis events occurred. Higher sweet food intake was associated with an increased risk of chronic pancreatitis (HR<sub>Quartile 4 vs. Quartile 1</sub>: 1.87; 95% confidence interval [CI], 1.32–2.64; <em>P</em><sub>trend</sub> < 0.001) but not with pancreatic cancer (HR<sub>Quartile 4 vs. Quartile 1</sub>: 1.11; 95% CI, 0.80–1.53; <em>P</em><sub>trend</sub> = 0.60) or acute pancreatitis (HR<sub>Quartile 4 vs. Quartile 1</sub>: 0.95; 95% CI, 0.72–1.23; <em>P</em><sub>trend</sub> = 0.65).</div></div><div><h3>Conclusions</h3><div>Findings from this cohort study suggest that lower intake of sweet foods may reduce the risk of chronic pancreatitis.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"143 ","pages":"Article 113032"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NutritionPub Date : 2026-03-01Epub Date: 2025-11-12DOI: 10.1016/j.nut.2025.113025
Saleha Abdusamed Mohammed B.Sc., M.Sc., Ebrahim Hassen Aden B.Sc., M.Sc., Kalid Hassen Ibrahim B.Sc., M.Sc.
{"title":"Nutritional status and dietary diversity as determinants of academic performance among primary school children in Jigjiga, Somali Region, Ethiopia: A cross-sectional study","authors":"Saleha Abdusamed Mohammed B.Sc., M.Sc., Ebrahim Hassen Aden B.Sc., M.Sc., Kalid Hassen Ibrahim B.Sc., M.Sc.","doi":"10.1016/j.nut.2025.113025","DOIUrl":"10.1016/j.nut.2025.113025","url":null,"abstract":"<div><h3>Background</h3><div>School-aged children in resource-limited settings remain understudied in nutrition research, despite the well-documented effects of malnutrition on cognitive development and academic achievement.</div></div><div><h3>Objective</h3><div>To examine the associations between anthropometric status, household dietary diversity (DD), and academic performance among primary school children in Jigjiga, Somali Region, Ethiopia.</div></div><div><h3>Methods</h3><div>A school-based cross-sectional study was conducted among 345 children aged 5 to 15 y, selected through stratified random sampling from five urban schools. Nutritional status was assessed using WHO <em>z</em>-scores for height-for-age (stunting), weight-for-age (underweight), and BMI-for-age (wasting). Household DD was measured using the Household Dietary Diversity Score, and academic performance was assessed from standardized school records. Data were analyzed with SPSS version 25, and statistical significance was set at <em>P</em> < 0.05. Multivariable logistic regression was used to identify factors associated with nutritional and academic outcomes.</div></div><div><h3>Results</h3><div>Undernutrition was prevalent, with 28.2% of children underweight, particularly girls and those aged 5 to 7 y. Although most households reported adequate DD, children from families with low diversity consistently showed poorer academic performance. Normal nutritional status was associated with better educational outcomes. Parental characteristics also mattered: government employment and higher paternal education were linked with improved nutritional status in children.</div></div><div><h3>Conclusions</h3><div>Undernutrition, especially underweight, significantly affects school-aged children in Jigjiga, particularly girls and younger children. DD and parental socioeconomic conditions strongly correlate with children’s nutritional status and academic performance. These findings suggest the need for targeted, school-based nutrition programs and context-specific interventions, though causal relationships cannot be inferred from this cross-sectional study.</div></div>","PeriodicalId":19482,"journal":{"name":"Nutrition","volume":"143 ","pages":"Article 113025"},"PeriodicalIF":3.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145733790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}