Obstetrics and Gynecology International最新文献

{"title":"Diagnostic Test of <i>Transforming Growth Factor-Beta</i> 1 (TGF-<i>β</i>1) in Menstrual Blood with Endometriosis.","authors":"Kemas Yusuf Effendi, Excellena Nasrul, Iskandar Zulqarnain, Theodorus, Rizani Amran, Heriyadi Manan, Adnan Abadi, Fatimah Usman, Cindy Kesty","doi":"10.1155/2023/9970818","DOIUrl":"10.1155/2023/9970818","url":null,"abstract":"<p><strong>Background: </strong>Endometriosis is a benign disorder that is generally defined as the presence of endometrial glands and stroma outside their normal location. TGF-<i>β</i>1 is found in stromal cells and its expression is increased in epithelial cells of endometriotic cysts. Endometriosis diagnostics take a long time, so new markers are needed to diagnose endometriosis. This study aims to determine the diagnostic value of TGF-<i>β</i>1 in menstrual blood in diagnosing endometriosis.</p><p><strong>Method: </strong>Diagnostic tests to compare eutopic endometrial TGF-<i>β</i>1 levels from menstrual blood of patients with suspected endometriosis were undertaken in the Obstetrics and Gynecology Department of Dr. Mohammad Hoesin General Hospital, Faculty of Medicine, Sriwijaya University, Palembang, from July 2019 to November 2020. 50 patients who were suspected with endometriosis met the inclusion criteria. Comparison of TGF-<i>β</i>1 levels between endometriosis and nonendometriosis patients was analyzed using the Mann-Whitney test. The cutoff point of the TGF-<i>β</i>1 level towards the histopathological outcome was obtained using the ROC curve. Data analysis was performed by using SPSS version 22.0.</p><p><strong>Results: </strong>In this study, endometriosis patients were 31.6 ± 6.55 years of age with a range of 20 to 46 years. In statistical analysis, there was no difference in BMI (<i>p</i> = 0.181) and BMI classification (<i>p</i> = 0.207), the history of contraception (<i>p</i> = 0.097), infertility (<i>p</i> = 1.000), and dysmenorrhoea (<i>p</i> = 1.000) between endometriosis and nonendometriosis patients. In the study, there were differences in TGF-<i>β</i>1 between endometriosis and nonendometriosis patients (<i>p</i> ≤ 0.001). By using the ROC curve, the cutoff point for TGF-<i>β</i>1 levels has the best sensitivity and specificity, which is 515 ng/ml. The TGF-<i>β</i>1 level has a sensitivity of 80%, a specificity of 90%, a positive predictive value (PPV) of 0.969, a negative predictive value (NPV) of 0.529, a positive likelihood ratio of 8, a negative likelihood ratio of 0.222, and an accuracy of 0.820 to the endometriosis outcome.</p><p><strong>Conclusion: </strong>It can be concluded that the TGF-<i>β</i>1 level has a very good diagnostic value in establishing endometriosis diagnostics. This trial is registered with ISRCTN72218532.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2023 ","pages":"9970818"},"PeriodicalIF":1.9,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10728358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138797674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Melatonin Ameliorates Ovarian Hyperstimulation Syndrome (OHSS) through SESN2 Regulated Antiapoptosis.","authors":"Min Zheng, Mei Liu, Cong Zhang","doi":"10.1155/2023/1121227","DOIUrl":"10.1155/2023/1121227","url":null,"abstract":"<p><strong>Background: </strong>Ovarian hyperstimulation syndrome (OHSS) is one of the most severe complications after ovarian stimulation during assisted reproductive technology (ART). However, its pathogenesis still remains unclear. Melatonin is an important antioxidant factor in female reproduction and Sestrin-2 (SESN2) is reported to be involved in cellular response to different stress conditions. Whether or not melatonin and SESN2 are involved in OHSS is still a question to us clinicians.</p><p><strong>Methods and results: </strong>We collected the granulosa cells of OHSS patients and focused on the role of SESN2 in OHSS. We also studied the role and mechanism of melatonin plays in OHSS patients. We found that the expression of SESN2 was increased in the granulosa cells of OHSS patients (<i>n</i> = 24) than those in controls (<i>n</i> = 15). Incubation with angiotensin II (1 <i>μ</i>M, 2 <i>μ</i>M) in HUVECs and H2O2 (0.1 mM, 0.2 mM) in KGNs increased the generation of ROS concurrent with the increased expression of SESN2, while melatonin treatment partly restored SESN2 levels. The mechanism study demonstrated that SESN2 was deeply involved in the regulation of AMPK and mTOR, whereas melatonin partially restored angiotensin II or H2O2 induced the activation of AMPK phosphorylation and the inhibition of mTOR, 4EBP1 and S6K1 phosphorylation, all of which could trigger cell apoptosis.</p><p><strong>Conclusions: </strong>These findings indicated that melatonin attenuated ROS-induced apoptosis through SESN2-AMPK-mTOR in OHSS. Thus, melatonin is likely to be a potential and important therapeutic agent for treating and preventing OHSS.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2023 ","pages":"1121227"},"PeriodicalIF":1.9,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71484512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing Surgical and Oncological Outcomes between Indocyanine Green (ICG) Sentinel Lymph Node Mapping with Routine Lymphadenectomy in the Surgical Staging of Early-Stage Endometrioid Endometrial Cancer.","authors":"Krystal Miao Lin Koh,&nbsp;Zheng Yuan Ng,&nbsp;Felicia Hui Xian Chin,&nbsp;Wai Loong Wong,&nbsp;Junjie Wang,&nbsp;Yong Kuei Lim","doi":"10.1155/2023/9949604","DOIUrl":"10.1155/2023/9949604","url":null,"abstract":"<p><strong>Methods: </strong>A retrospective single-centre cohort study of patients with early-stage endometrioid endometrial cancer undergoing staging surgery (total hysterectomy, bilateral salpingo-oophorectomy with/without pelvic lymph node, and/or para-aortic lymph node dissection (PLND)) with either SLN mapping or routine lymphadenectomy between July 2017 and December 2018.</p><p><strong>Results: </strong>203 cases with clinical and radiological International Federation of Gynaecology and Obstetrics (FIGO) stage I endometrioid endometrial cancer were included, out of which 109 cases underwent SLN mapping and 94 cases complete lymphadenectomy. Compared to the PLND group, the SLN group had shorter operative time (129 vs. 162 minutes), less blood loss (100 vs. 300 ml), and decreased length of postoperative hospital stay (3 vs. 4 days) (<i>p</i> < 0.001). The lymph node metastases detection rate was 4.6% and 7.4% for the SLN and PLND groups, respectively (<i>p</i> = 0.389). With a median follow-up of 14 months for the SLN and 15 months for the PLND group, the disease-free (DFS) and overall survival (OS) were comparable for both at 13 months (<i>p</i> = 0.538 and <i>p</i> = 0.333, respectively).</p><p><strong>Conclusion: </strong>SLN mapping has been shown to be an acceptable alternative to routine lymphadenectomy in the surgical staging of early-stage endometrial cancer in our centre, with a comparable lymph node metastases detection rate, DFS and OS, and reduction in operative morbidity. Our results with SLN mapping reproduce comparable outcomes to those reported in the literature.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2023 ","pages":"9949604"},"PeriodicalIF":1.9,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10597725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50162381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancies in Women with a Previous Complete Uterine Rupture.","authors":"Iqbal Al-Zirqi, Siri Vangen","doi":"10.1155/2023/9056489","DOIUrl":"10.1155/2023/9056489","url":null,"abstract":"<p><strong>Objective: </strong>To study the outcomes of new pregnancies after a previous complete uterine rupture.</p><p><strong>Design: </strong>Descriptive study based on population data from the Medical Birth Registry of Norway, the Patient Administration System, and the medical records. <i>Sample</i>. Maternities with a previous complete uterine rupture in Norway during the period 1967-2011 (<i>N</i> = 72), extracted from 2 455 797 maternities.</p><p><strong>Method: </strong>We measured the rate of new complete ruptures and partial ruptures, as well as the maternal and perinatal outcomes of these pregnancies. The characteristics of both previous ruptures and new ruptures were described.</p><p><strong>Results: </strong>Among 72 maternities, there were thirty-seven with previous ruptures in the lower segment (LS) and 35 outside the LS. We found three new complete ruptures and six uneventful partial ruptures, resulting in a rate of 4.2% and 8.3%, respectively. All three complete ruptures occurred preterm in scars outside the LS. The rate of the new complete rupture was 0% in those with previous ruptures in the LS and 8.6% in those with previous ruptures outside the LS. The corrected perinatal mortality was 1.3%, and prematurity (<37 weeks) was high (36.1%); this was noticed even in the absence of new ruptures and was mostly iatrogenic. Two hysterectomies were performed in the absence of rupture and two cases had abnormal invasive placenta.</p><p><strong>Conclusion: </strong>The prognosis for pregnancies after a previous complete uterine rupture is favorable. Prematurity is a problem caused by both obstetrician and mother's anxiety; therefore, the timing of delivery is the most challenging. Management should include careful counseling, vigilance for symptoms, and immediate delivery when a rupture is suspected.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2023 ","pages":"9056489"},"PeriodicalIF":1.6,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9935781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10826747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Management, and Impact of Dysmenorrhea on the Lives of Nurse and Midwife Trainees in Northern Ghana.","authors":"Abubakari Wuni,&nbsp;Brenda Abena Nyarko,&nbsp;Mudasir Mohammed Ibrahim,&nbsp;Issahaka Abdulai Baako,&nbsp;Iddrisu Sisala Mohammed,&nbsp;Camillus Buunaaisie","doi":"10.1155/2023/8823525","DOIUrl":"https://doi.org/10.1155/2023/8823525","url":null,"abstract":"<p><strong>Background: </strong>Dysmenorrhea is the most common gynecological problem affecting the majority of female students in the nursing profession today. They often experience severe pain that is not only incapacitating but also has a significant impact on their day-to-day college life, academic, and clinical performance.</p><p><strong>Aim: </strong>This study was conducted to assess the prevalence, management, and impact of dysmenorrhea on the lives of nurse and midwife trainees in northern Ghana.</p><p><strong>Methods: </strong>A descriptive cross-sectional design with a quantitative approach to data collection was employed to collect data from nurse and midwife trainees in three colleges of nursing and/or midwifery in the northern region of Ghana. A proportionate stratified random sampling technique was used to recruit 303 respondents for the study. After gaining permission from various institutions, data were collected by using a structured questionnaire from 13^th September to 28^th October, 2022. Stata (special edition) for Windows version 17.0 was used for the statistical analyses.</p><p><strong>Results: </strong>The study revealed a high prevalence of dysmenorrhea among female nursing students (66.7% and 95% CI: 0.611-0.720). More than half of the respondents (67.3%) experienced loss of appetite for food. The most common site of most intense pain was the pelvis and lower abdomen (98.0%). A greater proportion of students (65.8%) used antispastic drugs to reduce pain. The respondents' concentration in the classroom was greatly affected (77.2%) as well as normal physical activities (58.4%). A multivariable logistic regression analysis revealed that the odds of dysmenorrhea are 2.67 times higher when the duration of menstruation is 4-5 days (AOR = 1.82, 95% CI = 1.13-6.28, and <i>p</i> = 0.024) than a duration of 1-3 days. Having urinary tract infections was associated with 3.56 times higher odds of dysmenorrhea (AOR = 3.56, 95% CI = 0.98-12.86, and <i>p</i> = 0.053). Again, the odds of dysmenorrhea were also four times higher among respondents with a family history of the same condition (AOR = 4.05, 95% CI = 2.16-7.61, and <i>p</i> = 0.001).</p><p><strong>Conclusion: </strong>The current study revealed a high prevalence of dysmenorrhea among nurse and midwife trainees in the northern part of Ghana. The majority of the respondent experienced loss of appetite and intense pain in the pelvis and lower abdomen, and their concentration during lectures was also significantly affected. The most predominant nonpharmacological method used for reducing the pain was sleep and the application of warm objects on the abdomen.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2023 ","pages":"8823525"},"PeriodicalIF":1.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10413885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Concepts for Intrauterine Device Placement at Caesarean Delivery: Description of Technique and Video Recording.","authors":"G Justus Hofmeyr,&nbsp;Kyungu M Kime","doi":"10.1155/2023/4410984","DOIUrl":"https://doi.org/10.1155/2023/4410984","url":null,"abstract":"<p><p>The International Federation of Gynaecology and Obstetrics recommend digital insertion of the copper intrauterine device (IUD) during caesarean delivery and note the risk of thread inclusion in the uterotomy closure and nonvisibility of threads at follow-up. We describe a novel method of inserting the IUD with the insertion straw and directing the lower end of the straw through the cervix for retrieval after the operation, to protect and ensure alignment of the threads. We also describe a simple method of lengthening one thread with part of the other thread, to avoid risks associated with braided suture extensions.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2023 ","pages":"4410984"},"PeriodicalIF":1.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9475845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unintended Pregnancy and Associated Factors among Pregnant Women Attending Antenatal Care Unit in Public Health Facilities of Dire Dawa City, Eastern Ethiopia, 2021.","authors":"Andinet Ayele,&nbsp;Neil Abdurashid,&nbsp;Mickiale Hailu,&nbsp;Bereket Tefera","doi":"10.1155/2023/8100462","DOIUrl":"https://doi.org/10.1155/2023/8100462","url":null,"abstract":"<p><strong>Background: </strong>Unintended pregnancy refers to a pregnancy that is either mistimed or unwanted. Unintended pregnancy has been a troubling public health and reproductive health issue, which imposes appreciable adverse consequences on the mother, child, and the public in general. Globally 121 million unplanned pregnancies occurred from 2015 to 2019. A significant proportion (61%) of these pregnancies ended in abortions each year. In Ethiopia, the challenges of unintended pregnancy and its related complications still exist because of the high rate of unmet need for contraceptives. In addition, no research has been conducted on unintended pregnancy among pregnant women in Dire Dawa city administration.</p><p><strong>Objective: </strong>To determine the prevalence of unintended pregnancy and associated factors among pregnant women attending antenatal care public health facilities in Dire Dawa in 2021.</p><p><strong>Methods: </strong>A facility-based cross-sectional study was conducted. After being chosen randomly, 382 pregnant women were interviewed at 9 urban public health facilities. A pretested questionnaire was used to collect data, entered into Epi Info 7, and exported into SPSS version 25 for analysis. The variables, which were significant at <i>P</i> ≤ 0.25 in bivariate analysis, were included in multivariable analysis. Statistical significance was declared at a <i>P</i> value <0.05 and a 95% CI.</p><p><strong>Results: </strong>In this study, the prevalence of unintended pregnancy was 23.8% at 95% CI (19.8-28.3). The following factors were associated with unintended pregnancy: single women (AOR = 10.93, 95% CI 3.65-32.74), low family income (2000 ETB) (AOR = 4.01, 95% CI 1.73-9.28), parity 3 (AOR = 10.3, 95% CI 4.07-25.84), no history of family planning use (AOR = 5.91, 95% CI 2.46-14.21), and husband decision-making role on reproductive health (AOR = 2.956, 95% CI 1.048-8.340). <i>Conclusion and Recommendations</i>. The prevalence of unintended pregnancy was relatively high in this study. Efforts should be made to scale up women's decision-making power on family planning services and give support to empower women economically. There is the need to promote family planning services to minimize unintended pregnancy and to decrease parity and family size.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2023 ","pages":"8100462"},"PeriodicalIF":1.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10295045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Primary Dysmenorrhoea and Its Impact on Academic Performance among Croatian Students during the COVID-19 Pandemic.","authors":"Marta Horvat,&nbsp;Doroteja Pavan Jukić,&nbsp;Lovro Marinović,&nbsp;Dina Bursać,&nbsp;Rosana Ribić,&nbsp;Marijana Neuberg,&nbsp;Danijel Bursać","doi":"10.1155/2023/2953762","DOIUrl":"https://doi.org/10.1155/2023/2953762","url":null,"abstract":"<p><strong>Background: </strong>Dysmenorrhoea is one of the most common gynaecological problems. Therefore, it is important to investigate its impact during the COVID-19 pandemic which has a great impact on the lives of menstruating people all over the world.</p><p><strong>Aim: </strong>To determine the prevalence and impact of primary dysmenorrhoea on academic performance among students during the pandemic.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted in April 2021. All data were collected by an anonymous self-assessed web-based questionnaire. Due to voluntary participation in the study, 1210 responses were received, but 956 were left for analysis after exclusion criteria were applied. Descriptive quantitative analysis was performed and Kendall rank correlation coefficient was used.</p><p><strong>Results: </strong>The prevalence of primary dysmenorrhoea was 90.1%. Menstrual pain was mild in 7.4% of cases, moderate in 28.8%, and severe in 63.8%. The study found that primary dysmenorrhoea has a great perceived impact on all included aspects of academic performance. Most affected were concentration in class in 810 (94.1%) and doing homework and learning in 809 (94.0%) female students. There is also a correlation between menstrual pain intensity and its impact on academic performance (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Our study found that the prevalence of primary dysmenorrhoea among students at the University of Zagreb is high. Painful menstruation greatly impacts academic performance and therefore it is important to do more research on this topic.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2023 ","pages":"2953762"},"PeriodicalIF":1.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9975932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative Neutrophil Lymphocyte Ratio in Prediction of Adnexal Mass Torsion.","authors":"Asmita Ghimire,&nbsp;Sailaja Ghimire,&nbsp;Asmita Shrestha,&nbsp;Samriddha Raj Pant,&nbsp;Nilam Subedi,&nbsp;Padam Raj Pant","doi":"10.1155/2023/3585189","DOIUrl":"https://doi.org/10.1155/2023/3585189","url":null,"abstract":"<p><strong>Aims: </strong>Adnexal torsion commonly affects reproductive age group females. Prompt diagnosis and early management help in the preservation of fertility. However, its diagnosis is challenging. Preoperative diagnosis can be suspected in only 23-66% of the cases and half of the patients operated for adnexal torsion have different diagnosis. This article thus aims to identify the diagnostic value of preoperative neutrophil lymphocyte ratio in adnexal torsion in comparison with other untwisted unruptured ovarian cysts.</p><p><strong>Methods: </strong>This was a retrospective study conducted in the duration of five years from 1st January 2016 to 1st January 2020. The data about demographic parameters, hematological parameters, operative approach, operative technique, and histopathological reports were derived from an electronic database and documented on proforma. SPSS was used for statistical analysis. Logistic regression analysis and influence of each factor on preoperative diagnosis of Adnexal torsion was evaluated.</p><p><strong>Results: </strong>A total of 125 patients were included in the article (adnexal torsion group <i>n</i> = 25, untwisted unruptured ovarian cyst group <i>n</i> = 100). There was no statistically significant difference in comparison to age, parity, and abortion between both groups. Most patients had undergone laparoscopic surgery which was based on surgeon's skill and preference. Nineteen (78%) patients in the adnexal torsion group underwent oophorectomy while infarcted ovary was seen in only 4 cases. Among the blood parameters, only neutrophil-lymphocyte ratio (NLR) >3 was found to be statistically significant under logistic regression analysis. Most common adnexal pathology to undergo torsion was serous cyst.</p><p><strong>Conclusion: </strong>Preoperative neutrophil-lymphocyte ratio can be a predictive marker for diagnosis of adnexal torsion and can differentiate it from untwisted unruptured ovarian cysts.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2023 ","pages":"3585189"},"PeriodicalIF":1.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10867092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Dry Heat Application on Perineal Pain and Episiotomy Wound Healing among Primipara Women.","authors":"Naglaa Zaki Hassan Roma,&nbsp;Rasha Mohamed Essa,&nbsp;Zohour Ibrahim Rashwan,&nbsp;Afaf Hassan Ahmed","doi":"10.1155/2023/9572354","DOIUrl":"https://doi.org/10.1155/2023/9572354","url":null,"abstract":"<p><strong>Background: </strong>Women who undergo perineal episiotomy can be affected by several complications such as bleeding, infection, perineal pain, dyspareunia, reduction of sexual desire, as well as urinary and anal incontinence. Perineal pain related to episiotomy has been reported to interfere with women's daily activities postpartum and can prevent proper breastfeeding, proper rooming-in, and maternal-infant bonding. The purpose of this study was to determine the effect of dry heat application on perineal pain and episiotomy wound Healing among primipara women.</p><p><strong>Method: </strong>A quasi-experimental, two-group, pre-post-test research study was conducted at the postnatal inpatient ward and the outpatient clinic of the El-Shatby Maternity University Hospital in Alexandria. A sample of 100 parturient women was divided into the following two groups at random: dry heat and moist (control) heat. Women in the moist heat group were advised to sit in a basin (tub) of warm water for 10 minutes, while those in the dry heat group were instructed to set an infrared light (230 volts) at a distance of 45 cm from the perineum after 12 hours post episiotomy. Both interventions were applied twice a day for ten consecutive days. They evaluated the severity of their perineal pain at baseline and repeated it on the 5^th and 10^th days after obtaining the interventions while the episiotomy wound healing was assessed on the 5^th and 10^th days.</p><p><strong>Results: </strong>It was discovered that the dry heat group had a significantly improved episiotomy wound healing as regards perineal redness, edema of the perineal area, ecchymosis, wound discharge, and approximation of wound edges on the 5th (<i>P</i> < 0.001, <i>P</i> < 0.001, <i>P</i> < 0.007, <i>P</i> < 0.003, and <i>P</i> < 0.001, respectively) and 10th day after intervention (<i>P</i> < 0.001, <i>P</i> < 0.001, <i>P</i> < 0.001, <i>P</i> < 0.005, and <i>P</i> < 0.001, respectively) than the moist heat group. The primipara women had significantly lower perineal pain intensity in the dry heat group on the 5th and 10th days after intervention than in the moist heat group (^MH <i>P</i> < 0.001 for the dry heat group and ^MH <i>P</i> = 0.004 for the moist heat group).</p><p><strong>Conclusion: </strong>The application of dry heat promoted episiotomy wound healing among primipara women and reduced their perineal pain during early postpartum days than moist heat.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2023 ","pages":"9572354"},"PeriodicalIF":1.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10539928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}