{"title":"Prediction Model for Successful Induction of Labor by Fetal Middle Cerebral Artery Pulsatility Index and Obstetric Factors in Term Pregnancy: A Prospective Cohort Study.","authors":"Vaishali Gautam, Harsha S Gaikwad, Banashree Nath, Mukesh Shukla, Priti Kumari","doi":"10.1155/ogi/7881711","DOIUrl":"10.1155/ogi/7881711","url":null,"abstract":"<p><p><b>Objective:</b> Our study aimed to examine ultrasound and obstetric parameters, explore their interrelationships, and assess their predictive ability in determining the success of labor induction. <b>Methodology:</b> Women with uncomplicated singleton pregnancy at a gestational age of 40 weeks and 3 days with fetal cephalic presentation, having intact fetal membranes and unfavorable Bishop score (BS < 6) were recruited for the study. Ultrasound examination was performed to measure cervical length (CL), estimated fetal weight (EFW), and Doppler velocimetry of fetal cerebral vessels in each patient before induction. We proposed to combine the variables of CL, EFW, BS, and middle cerebral artery pulsatility index (MCA PI) to devise a model for the prediction of successful induction of labor (IOL). IOL was performed with intracervical prostaglandin E2 gel (3 g gel/0.5 mg dinoprostone) applied 6 h apart if needed, not more than 2 doses, followed by oxytocin infusion for up to 6 h. Successful induction was defined as the initiation of active labor at any stage of the induction process. <b>Results:</b> Among the 70 enrolled women, only 29 (41.4%) women responded to induction. CL, BS, and mean value of fetal MCA PI had significant differences in women who responded from those who did not respond to the IOL. The prediction model for the success of induction with the four variables of MCA PI, BS, and CL has a sensitivity of 100% and specificity of 90.2% (AUC 0.982, 95% CI: 0.96-1.00, <i>p</i> < 0.001) with the upper cutoff of 0.47. EFW showed to have no effect on the outcome parameter. <b>Conclusion:</b> A model comprising MCA PI, CL, and BS has an excellent prediction value to assess the response to IOL in women at term pregnancy. When a single parameter has to be evaluated, CL is the best maternal factor to predict the success of induction.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2025 ","pages":"7881711"},"PeriodicalIF":1.3,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12425628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum to \"Association of Hormonal Contraceptives with Depression among Women in Reproductive Age Groups: A Cross-Sectional Analytic Study\".","authors":"","doi":"10.1155/ogi/9871215","DOIUrl":"10.1155/ogi/9871215","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/2024/7309041.].</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2025 ","pages":"9871215"},"PeriodicalIF":1.3,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12425629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating Treatment Strategies in Advanced Endometrial Cancer: Primary Cytoreductive Surgery Versus Neoadjuvant Chemotherapy Followed by Interval Debulking Surgery-A Ten-Year Single-Centre Experience.","authors":"Mohamed Abdelwanis Mohamed Abdelaziz, Ahmed Mohamed, Siddesh Prabhulingam, Ambreen Yaseen, Khaled Sabrah, Fatini Hussin, Riyam Aldulaimi, Hazem Elsheikh, Ashu Loona, Irshad Soomro, Ketankumar Gajjar, Benjamin Wormald","doi":"10.1155/ogi/7202848","DOIUrl":"10.1155/ogi/7202848","url":null,"abstract":"<p><p><b>Introduction/Background:</b> Management of advanced endometrial cancer (EC) presents a significant therapeutic challenge, with ongoing debate regarding optimal treatment sequencing. Primary cytoreductive surgeries (PCSs) with adjuvant therapy and neoadjuvant chemotherapy followed by interval Debulking surgery (NACT-IDS) are both employed as treatment strategies. This study analyses outcomes of both treatment strategies in Nottingham University Hospitals Cancer Centre. <b>Methodology:</b> We conducted a retrospective cohort analysis of patients with advanced EC (FIGO Stages III-IV) treated at our centre between 2013 and 2023. Patients who received either PCS with adjuvant therapy or neoadjuvant chemotherapy followed by interval Debulking surgery (NACT-IDS) are included in the study. Data collection included demographic characteristics, treatment approaches, surgical parameters, and outcome measures. Primary outcomes were progression-free survival (PFS) and overall survival (OS). Secondary outcomes included perioperative outcomes and recurrence patterns. <b>Results:</b> Treatment pathways included NACT-IDS (<i>n</i> = 8) and PCS with adjuvant therapy (<i>n</i> = 57). Stage IV disease was notably more prevalent in patients who received NACT-IDS therapy compared to the PCS group (75.0% versus 5.3%, <i>p</i> < 0.001). Analysis revealed a PFS duration of 18.5 months for NACT-IDS patients, whilst PCS patients demonstrated a longer duration of 35.5 months (HR 1.18, 95% CI: 0.56-2.48, <i>p</i>=0.328). Median OS was 22.0 months in the NACT-IDS group versus 41.0 months in the PCS group (HR 1.35, 95% CI: 0.64-2.83, <i>p</i>=0.145). Mean operative time was longer in the NACT-IDS group (239.7 vs 165.5 min, <i>p</i>=0.209). All NACT-IDS procedures were performed via open laparotomy compared to 49.1% in the PCS group (<i>p</i> < 0.001). Hospital stay was significantly longer in the NACT-IDS group (median 8 vs 3 days, <i>p</i>=0.036). Radiotherapy was administered to 25.0% (<i>n</i> = 2) of NACT-IDS patients and 59.6% (<i>n</i> = 34) of PCS patients. Recurrence rates were higher in the NACT-IDS group, 37.5%, compared to 33.3% in the PCS patients (<i>p</i>=0.823). <b>Conclusion:</b> This comprehensive analysis provides valuable insights into treatment outcomes and surgical parameters for advanced EC. Whilst the small sample size of the NACT-IDS cohort limits the ability to draw definitive conclusions, the study provides meaningful evidence that can inform clinical decision-making. The findings lay important groundwork for future prospective, multicentre studies aimed at optimising patient selection and treatment sequencing in this challenging disease.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2025 ","pages":"7202848"},"PeriodicalIF":1.3,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pelvic Arterial Embolisation in Obstetric and Gynaecological Haemorrhage: A Single-Centre Case Series.","authors":"Monica Narula, Tuan Phan, Kiran Atmuri","doi":"10.1155/ogi/9932410","DOIUrl":"10.1155/ogi/9932410","url":null,"abstract":"<p><p><b>Background:</b> Obstetric and gynaecological haemorrhage contributes significantly to morbidity and mortality globally. Pelvic arterial embolisation has been described as a management option for emergency haemorrhage not responsive to conservative measures. Despite encouraging outcomes, it is not widely utilised. <b>Aim:</b> This study aims to assess efficacy and early complications of pelvic arterial embolisation as a therapy for obstetric and gynaecological haemorrhage not controlled by conservative methods. <b>Materials and Methods:</b> This retrospective single-centre case series reviewed all cases of acute haemorrhage from obstetric or gynaecological causes referred for angiographic embolisation between 2014 and 2020. <b>Results:</b> Twelve patients underwent pelvic arterial embolisation with a 100% technical success rate and 91.6% clinical success rate. There were no major early complications. <b>Conclusion:</b> Pelvic arterial embolisation is a safe and effective option for obstetric and gynaecological haemorrhage not responsive to conservative management.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2025 ","pages":"9932410"},"PeriodicalIF":1.3,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12375861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Explaining the Phenomenon of Therapeutic Deadlock in Infertile Women: A Qualitative Phenomenological Study.","authors":"Somayeh Souri, Behzad Imani, Maryam Maddineshat","doi":"10.1155/ogi/7574541","DOIUrl":"10.1155/ogi/7574541","url":null,"abstract":"<p><p><b>Background and Objective:</b> Infertility is an unpredictable condition that presents various physical, psychological, and financial challenges. The uncertainty surrounding the success of treatment options can hinder individuals' ability to cope, potentially leading to adverse outcomes. This study aimed to explore the phenomenon of therapeutic deadlock in women experiencing infertility. <b>Method:</b> This descriptive phenomenological study was conducted from March to November 2024 at infertility centers affiliated with Hamadan University of Medical Sciences in Iran. A purposive sample was used, and 23 semistructured, in-depth, face-to-face interviews were conducted with women who had experienced primary infertility. The collected data were analyzed using the Colaizzi method. <b>Findings:</b> In exploring experiences of infertility, three main themes emerged. (1) Feelings that they were in a last desperate struggle: This theme includes exploring unconventional infertility treatments, seeking treatment with skepticism, and taking risks to achieve the goal. (2) Negative thoughts to overcome a deadlock: This encompasses thoughts of separation and suicidal thoughts. (3) Intentions to resist surrendering to fate: This theme highlights resistance through faith in god against feelings of surrendering to fate. <b>Conclusion:</b> This study examines the phenomenon of therapeutic deadlock among infertile women, highlighting how their cultural and social contexts shape their treatment choices. Despite facing hesitations and potential risks, these women seek treatment in various ways. When confronted with a deadlock in their journey, they often experience negative thoughts and employ different coping strategies, which range from resistance to faith in a higher power and sometimes surrendering to fate.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2025 ","pages":"7574541"},"PeriodicalIF":1.3,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12356679/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144874373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Cohort Study on Factors Affecting Sleep Quality in Women Undergoing Intrauterine Sperm Insemination (IUI) Treatment.","authors":"Zahra Vafaeian, Maryam Hassanzadeh Bashtian, Tooba Farazmand, Alireza Afshari-Safavi, Seyed Kaveh Hojjat, Sepideh Hamdamiyan","doi":"10.1155/ogi/4749954","DOIUrl":"10.1155/ogi/4749954","url":null,"abstract":"<p><p><b>Introduction:</b> The stress associated with infertility can impact an individual's sleep status by affecting the hypothalamus and pituitary axis, potentially leading to sleep disorders. On the other hand, sleep disorders can further contribute to the development of depression and anxiety. This study aims to investigate the factors that influence sleep quality in women undergoing intrauterine sperm insemination (IUI) treatment. <b>Methods:</b> This research involved a prospective cohort study conducted on 131 infertile women aged 18-45 years who sought services at the infertility clinic of Bent Al-Hoda Hospital in Bojnurd City and a private clinic between 2020 and 2023. Data were gathered using a demographic questionnaire, the Beck Anxiety Inventory (BAI), the Beck Depression Inventory (BDI), and the Pittsburgh Sleep Quality Index (PSQI). Participants completed these questionnaires at three different time points: 0, 14, and 30 days in relation to the time of IUI. Data analysis was carried out using repeated-measures analysis of variance and generalized linear models. <b>Results:</b> The average age of the participating women was 29.85 years, with a standard deviation of 5.75. The overall prevalence of sleep quality disorder was 30.5%. Most patients reported mild to moderate disturbances in the delay of falling asleep. While no significant difference was observed in the comparison of average sleep disturbance scores at three different times, an increasing trend in anxiety and depression was noted in the second stage, followed by a decreasing trend in the third stage. In the presence of other variables, anxiety and depression demonstrated a significant relationship with sleep disorder (<i>p</i> < 0.001). <b>Conclusions:</b> Approximately one-third of infertile women were found to be suffering from a sleep quality disorder. The study underscores the significant impact of depression and anxiety on sleep quality disorders among infertile women. As a recommendation, it is advised to address the psychological well-being of infertile patients within infertility treatment clinics.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2025 ","pages":"4749954"},"PeriodicalIF":1.3,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144784900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gao Jiayin, Quratul Ain, Sun Haizhu, Xiaohong Qiu, Zhang Song
{"title":"The Prognosis of Endometriosis Correlates With Elevated Expression of LncRNA-ANRIL.","authors":"Gao Jiayin, Quratul Ain, Sun Haizhu, Xiaohong Qiu, Zhang Song","doi":"10.1155/ogi/9530832","DOIUrl":"10.1155/ogi/9530832","url":null,"abstract":"<p><p><b>Background:</b> Endometriosis is a chronic condition that affects the endometrium, the lining of the uterus. The endometrium typically thickens and discharges during the menstrual cycle, resulting in menstruation. Endometriosis is characterized by developing endometrial-like tissue outside of the uterus, typically on the ovaries, fallopian tubes, and other pelvic structures. This tissue can become inflamed, resulting in various symptoms, such as discomfort. Endometriosis is characterized by heavy menstrual bleeding, fatigue, painful urination or bowel movements, and infertility. Endometriosis is a benign pathological condition frequently seen in the gynecology department. This study classified 28 lncRNAs associated with endometriosis and other gynecological disorders and examined the expression of lncRNA-ANRIL in the eutopic and ectopic endometrium of patients with Ems. <b>Methods:</b> Quantitative reverse transcription (qRT)-PCR was utilized to explore the differences in ANRIL expression between endometriosis tissues and normal ovarian epithelium. Using this technique, the expression of ANRIL in vivo was assessed in 30 endometriosis specimens. A human endometriosis cell line was subjected to in vitro ANRIL knockdown so that the biological roles of the line could be discovered. The Transwell assay was successful in identifying migration and invasion. <b>Results:</b> The expression of ANRIL was much higher in endometriosis tissues than in normal ovarian epithelial tissues, and this difference was found to be strongly associated with the endometriosis stage. <b>Conclusions:</b> There was a positive correlation between the expression of ANRIL and the occurrence of endometriosis. Additionally, there was a close association between the expression of ANRIL and the etiology and development of endometriosis. This offers a potential basis for the early detection and treatment of endometriosis.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2025 ","pages":"9530832"},"PeriodicalIF":1.3,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12317816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144775892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeffrey R Boris, Edward C Shadiack, Elizabeth M McCormick, Laura E MacMullen, Ibrahim George-Sankoh, Frances Fitzgerald, Marni Falk
{"title":"The Long-Term Postural Orthostatic Tachycardia Syndrome Outcomes Survey-Gynecologic Findings: A Cross-Sectional Survey in Young Women.","authors":"Jeffrey R Boris, Edward C Shadiack, Elizabeth M McCormick, Laura E MacMullen, Ibrahim George-Sankoh, Frances Fitzgerald, Marni Falk","doi":"10.1155/ogi/8872884","DOIUrl":"10.1155/ogi/8872884","url":null,"abstract":"<p><p><b>Objective:</b> Postural orthostatic tachycardia syndrome (POTS) affects up to 3 million people in the United States. Although 78%-83% of POTS patients are female, gynecologic comorbidity has not been well-studied. We created an online questionnaire to assess outcomes in female patients with POTS formerly followed at a single-center pediatric POTS program. <b>Design:</b> Cross-sectional study. <b>Setting:</b> Single-center pediatric POTS program. <b>Population or Sample:</b> All female patients ≤ 18 years at diagnosis. <b>Methods:</b> We developed and distributed The Long-Term POTS Outcomes Survey with questions about diagnosis, therapy, education, employment, social impact, quality of life (QoL), and gynecologic symptoms and management. <b>Main Outcome Measures:</b> Gynecologic symptoms and QoL. <b>Results:</b> Regular menstrual cycles were seen in 81/167 participants (49.1%). POTS symptoms worsened prior to and during menses in 118/167 subjects (72.4%); hormonal contraceptive therapy helped to control symptoms in 52/110 subjects (50%). Menorrhagia, polycystic ovary syndrome, and endometriosis were not reported in higher numbers compared to the general population. <b>Conclusions:</b> Menstrual flow disorders are not more prevalent in younger females with POTS. Symptoms often worsen perimenstrually, and hormone therapy can help to reduce symptom severity. Further research is needed to better define optimal hormone therapy in suppressing perimenstrual symptoms.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2025 ","pages":"8872884"},"PeriodicalIF":1.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12283190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trends of Minimally Invasive Hysterectomy: Five Years of Experience.","authors":"Abdulrahman Khinkar, Afaf Felemban, Rahaf AlSomali, Norah AlSunayen, Ahmed Felemban, Joud Makki, Ghadeer Aljahdali","doi":"10.1155/ogi/2366445","DOIUrl":"10.1155/ogi/2366445","url":null,"abstract":"<p><p><b>Objectives:</b> This study aims to investigate the five-year trend of minimally invasive hysterectomy and identify factors associated with increased intraoperative and postoperative complications within the last five years (2017-2021). <b>Methods:</b> A retrospective chart review was performed between March 30th and April 10th, 2022, which included women who underwent total laparoscopic hysterectomy (TLH), laparoscopic subtotal hysterectomy (LSH), laparoscopic-assisted vaginal hysterectomy (LAVH), and robotic-assisted hysterectomy for benign gynecologic conditions, during the period January 2017 to December 2021. <b>Results:</b> There was an increase in the rate of performing minimally invasive hysterectomy procedures from 35 cases (12.5%) in 2017 to 85 cases (30.5%) in 2021. In addition, abnormal uterine bleeding was the most reported indication for minimally invasive hysterectomy (<i>n</i> = 84; 30.1%). Estimated blood loss was a significant predictor for both intraoperative complications (<i>p</i> < 0.001) and postoperative complications (<i>p</i>=0.004). <b>Conclusion:</b> Within the last five years, there has been an increasing trend of minimally invasive hysterectomy procedures at the OB-GYN department in KAMC, Saudi Arabia. And estimated blood loss is a significant predictor of intraoperative and postoperative complications of minimally invasive hysterectomy.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2025 ","pages":"2366445"},"PeriodicalIF":1.6,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Awareness, Practice, and Barriers Regarding Cervical Cancer Screening Among Women of Kageshwori Manohara Municipality, Nepal.","authors":"Pratima Pathak, Pratima Ghimire, Shyam Kala Chaudhary, Nebina Piya, Nira Shrestha","doi":"10.1155/ogi/5325540","DOIUrl":"10.1155/ogi/5325540","url":null,"abstract":"<p><p><b>Background:</b> Cervical cancer remains a global public health concern occurring in most cases in developing countries. Furthermore, it is a highly preventable disease; it remains to be the most common cancer among Nepalese women. Assessing women's awareness of cervical cancer and identifying barriers to screening are of vital importance for the utilization of cervical cancer screening. Therefore, this study has been conducted to assess information regarding awareness, practice, and barriers to cervical cancer screening among the women of Kageshwori Manohara Municipality of Kathmandu district in Nepal. <b>Methods:</b> Community-based descriptive cross-sectional study was conducted among 249 women aged 30-60 years by using a systematic random sampling technique. Data were collected from 1st to 29th February 2024 through a self-constructed semistructured tool using a face-to-face interview technique. Descriptive statistics and the chi-square tests were used for statistical analysis. <b>Results:</b> Out of the total respondents, only 10.4% had adequate awareness regarding cervical cancer screening and 38.6% of the respondents had ever been screened for cervical cancer. Among the respondents who had ever been screened, the majority (86.5%) of their last time screening was within 5 years. A statistically significant association was found between levels of awareness with the age of the respondents (<i>p</i>=0.031), educational level (<i>p</i>=0.013), and number of children (<i>p</i>=0.003). However, no significant association was found with other variables such as age at marriage, ethnicity, occupation, and monthly family income. Absence of symptoms (54.6%), unaware of screening (17.7%), and feeling of embarrassment (11.6%) were the most mentioned barriers to practicing cervical cancer screening among the respondents. <b>Conclusion:</b> The result of this study showed most of the respondents had an inadequate level of awareness and low experience of practicing cervical cancer screening. Therefore, community-based awareness campaigns and screening health camps should be conducted to increase knowledge and practice of cervical cancer screening.</p>","PeriodicalId":19439,"journal":{"name":"Obstetrics and Gynecology International","volume":"2025 ","pages":"5325540"},"PeriodicalIF":1.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}