Reproductive Outcomes of Dual Trigger versus hCG Alone in Women Undergoing In Vitro Fertilization with Fresh Embryo Transfer Cycles.

IF 1.6 Q3 OBSTETRICS & GYNECOLOGY
Obstetrics and Gynecology International Pub Date : 2024-07-09 eCollection Date: 2024-01-01 DOI:10.1155/2024/9972437
Fatma Ceren Guner, Murat Ozekinci, Ibrahim Inanc Mendilcioglu, Zeliha Kasabali
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引用次数: 0

Abstract

Aim: To investigate the effect of the triggering method on the results of fresh embryo transfer in patients who underwent gonadotropin-releasing hormone antagonist cycles.

Methods: The study was conducted retrospectively at a university-based tertiary reproductive center. The sample consisted of a total of 295 patients, of whom 111 were in the human chorionic gonadotropin (hCG) trigger group and 184 were in the dual trigger group. The main outcome measure of this study was the live birth rate, and secondary outcomes were the implantation rate, clinical pregnancy rate, miscarriage rate, and good-quality embryo rate.

Results: Patient demographics and baseline characteristics did not significantly differ between the dual and hCG trigger groups. The results also indicated statistically nonsignificant differences between the two groups in terms of the number of oocytes retrieved (p > 0.05), the number of mature oocytes (p > 0.05), and the fertilization rate (p > 0.05). The number of good-quality embryos (p=0.002) was higher in the dual trigger group compared with the hCG trigger group. However, the rates of clinical pregnancy and live births did not significantly differ between the groups (p > 0.05).

Conclusions: Although the number of total and high-quality embryos obtained was higher in the dual trigger group, there were no significant differences between the two groups in terms of pregnancy outcomes. The fresh embryo transfer yielded similar rates of implantation and live births in both trigger groups.

在接受体外受精和新鲜胚胎移植周期的妇女中,双重触发器与单用 hCG 的生殖结果对比。
目的:研究促性腺激素释放激素拮抗剂周期患者的触发方法对新鲜胚胎移植结果的影响:研究在一所大学的三级生殖中心以回顾性方式进行。样本共包括 295 名患者,其中 111 人属于人绒毛膜促性腺激素(hCG)触发组,184 人属于双触发组。这项研究的主要结果是活产率,次要结果是植入率、临床妊娠率、流产率和优质胚胎率:双重触发组和 hCG 触发组的患者人口统计学和基线特征无明显差异。结果还显示,两组在取卵数(P > 0.05)、成熟卵母细胞数(P > 0.05)和受精率(P > 0.05)方面的差异无统计学意义。与 hCG 触发组相比,双触发组的优质胚胎数量更高(p=0.002)。然而,两组的临床妊娠率和活产率没有显著差异(P > 0.05):结论:虽然双触发组获得的总胚胎数和优质胚胎数更多,但两组在妊娠结局方面没有显著差异。新鲜胚胎移植的植入率和活产率在两组中相似。
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来源期刊
Obstetrics and Gynecology International
Obstetrics and Gynecology International OBSTETRICS & GYNECOLOGY-
CiteScore
3.60
自引率
0.00%
发文量
26
审稿时长
19 weeks
期刊介绍: Obstetrics and Gynecology International is a peer-reviewed, Open Access journal that aims to provide a forum for scientists and clinical professionals working in obstetrics and gynecology. The journal publishes original research articles, review articles, and clinical studies related to obstetrics, maternal-fetal medicine, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine and infertility, reproductive endocrinology, and sexual medicine.
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