Nigerian Journal of Clinical Practice最新文献

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Investigation of Stresses Induced by Different Framework Materials in Implant-Supported Fixed Prosthesis Using Finite Element Analysis. 不同框架材料对种植体固定修复体应力的有限元分析。
IF 0.9 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2026-07-01 Epub Date: 2026-07-30 DOI: 10.4103/njcp.njcp_759_25
H C Basarir, E G Basaran, A I Zengingul
{"title":"Investigation of Stresses Induced by Different Framework Materials in Implant-Supported Fixed Prosthesis Using Finite Element Analysis.","authors":"H C Basarir, E G Basaran, A I Zengingul","doi":"10.4103/njcp.njcp_759_25","DOIUrl":"https://doi.org/10.4103/njcp.njcp_759_25","url":null,"abstract":"<p><strong>Background: </strong>In the implant-prosthesis complex, material choice and prosthetic design directly affect stress distribution and load transmission.</p><p><strong>Aim: </strong>This study aimed to compare the effects of different prosthetic framework materials on stress distribution in implant-supported fixed prostheses, using titanium and zirconia abutments, through three-dimensional finite element stress analysis.</p><p><strong>Methods: </strong>In this study, two titanium implants (4.1 mm × 10 mm) with one titanium and one zirconia abutment were modeled. Three-dimensional finite element models of implant-supported fixed prostheses were created using six framework materials and four veneering types, forming ten groups in total. After meshing bone and restorative structures, material properties (Poisson's ratio and Young's modulus) were assigned. A 178 N load was applied vertically and at 45° to the palatal surfaces of the maxillary central incisor and canine, and von Mises and tensile stresses were analyzed in the implants, abutments, peri-implant bone, and superstructures.</p><p><strong>Results: </strong>Under both loading conditions, the highest stresses occurred in the polyetheretherketone (PEEK) (implants, abutments) and fiber-reinforced composite (FRC) (superstructures) groups, while the lowest were found in the monolithic zirconia group. In cortical bone, stress was highest in the FRC group under oblique loading and in the PEEK group under vertical loading, whereas the Co-Cr group showed the lowest abutment stress under oblique loading.</p><p><strong>Conclusion: </strong>The study demonstrated that different framework materials significantly affect stress distribution within the implant, abutment, peri-implant bone, and prosthetic superstructure. Framework materials with lower elastic modulus were found to induce higher stress accumulation in the surrounding bone tissue, implant components, and crown structures.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"29 7","pages":"771-779"},"PeriodicalIF":0.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Anesthetic Efficacy of Mental/Incisive Nerve Block and Inferior Alveolar Nerve Block in the Treatment of Mandibular Premolars Diagnosed with Symptomatic Irreversible Pulpitis: A Systematic Review. 神经阻滞与下牙槽神经阻滞治疗症状性不可逆性牙髓炎下颌前磨牙麻醉效果的比较:系统综述。
IF 0.9 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2026-07-01 Epub Date: 2026-07-30 DOI: 10.4103/njcp.njcp_760_25
M B Alsharif, N Alqadi
{"title":"Comparison of the Anesthetic Efficacy of Mental/Incisive Nerve Block and Inferior Alveolar Nerve Block in the Treatment of Mandibular Premolars Diagnosed with Symptomatic Irreversible Pulpitis: A Systematic Review.","authors":"M B Alsharif, N Alqadi","doi":"10.4103/njcp.njcp_760_25","DOIUrl":"10.4103/njcp.njcp_760_25","url":null,"abstract":"<p><p>Inferior alveolar nerve block (IANB) is the most common technique for anesthetizing mandibular posterior teeth but has a high failure rate and potential complications, such as trismus, toxicity, and nerve injury. While alternative anesthetic techniques have been investigated for mandibular molars, limited research exists for mandibular premolars with symptomatic irreversible pulpitis. As the mental nerve innervates these teeth, the mental/incisive nerve block (MINB) may represent a suitable alternative. This systematic review evaluates the current evidence regarding the anesthetic efficacy of MINB compared to IANB for mandibular permanent premolars diagnosed with symptomatic irreversible pulpitis. A literature search was performed using the following databases: PubMed/MEDLINE, Web of Science, and the Cochrane Library, in addition to Google Scholar, ClinicalTrials.gov, and manual searching. Randomized clinical trials involving human subjects with mandibular premolars diagnosed with symptomatic irreversible pulpitis requiring non-surgical root canal treatment, comparing the anesthetic efficacy of MINB to IANB, conducted in adults, and published in the English language were selected. Studies published up to September 5, 2025, were included. Data extraction and risk-of-bias assessment were completed by two reviewers independently. Five studies met the inclusion criteria. They demonstrated a superior anesthetic success rate for MINB, reaching up to 93%, compared to IANB in anesthetizing symptomatic mandibular premolars diagnosed with irreversible pulpitis; however, the difference was not statistically significant. Although the difference was not statistically significant, it remains clinically relevant, particularly given that MINB provides a significantly quicker onset of anesthesia and significantly less injection pain.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"29 7","pages":"729-740"},"PeriodicalIF":0.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of the Systemic Immune-Inflammation Biomarkers (Systemic Immune-Inflammation Index [SII], Neutrophil-to-Lymphocyte Ratio [NLR], Platelet/Lymphocyte Ratio [PLR], Delta Neutrophil Index [DNI]) in Diagnosis and Complication Prediction of Geriatric Appendicitis. 全身免疫炎症生物标志物(全身免疫炎症指数[SII]、中性粒细胞与淋巴细胞比值[NLR]、血小板/淋巴细胞比值[PLR]、δ中性粒细胞指数[DNI])在老年阑尾炎诊断和并发症预测中的作用
IF 0.9 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2026-07-01 Epub Date: 2026-07-30 DOI: 10.4103/njcp.njcp_113_26
M Tepe, E Kaya, M S Gedik, A İ Kilci, F N Yaman, A İşler, E Cengiz, B Çelik, I Akbaş, M Alkaya, H Hakkoymaz
{"title":"Role of the Systemic Immune-Inflammation Biomarkers (Systemic Immune-Inflammation Index [SII], Neutrophil-to-Lymphocyte Ratio [NLR], Platelet/Lymphocyte Ratio [PLR], Delta Neutrophil Index [DNI]) in Diagnosis and Complication Prediction of Geriatric Appendicitis.","authors":"M Tepe, E Kaya, M S Gedik, A İ Kilci, F N Yaman, A İşler, E Cengiz, B Çelik, I Akbaş, M Alkaya, H Hakkoymaz","doi":"10.4103/njcp.njcp_113_26","DOIUrl":"https://doi.org/10.4103/njcp.njcp_113_26","url":null,"abstract":"<p><strong>Background: </strong>Acute appendicitis (AA) is an emergency surgical condition with diagnostic difficulty and a high complication rate in geriatric patients due to atypical presentations.</p><p><strong>Aim: </strong>This study evaluated the diagnostic and prognostic value of the systemic immune-inflammation index (SII), delta neutrophil index (DNI), and neutrophil-to-lymphocyte ratio (NLR) in patients aged ≥65 years.</p><p><strong>Methods: </strong>This retrospective study included 120 participants: 60 geriatric patients who underwent appendectomy for AA between January 2021 and October 2025 and 60 age-matched healthy controls. Demographic data, hematological parameters, and histopathological findings were analyzed. AA patients were classified as complicated or uncomplicated. Receiver operating characteristic (ROC) curve analysis was performed to assess diagnostic performance.</p><p><strong>Results: </strong>White blood cell count (WBC), absolute neutrophil count, NLR, DNI, and SII were significantly higher in the AA group compared with controls (P < 0.05). Patients with complicated AA had higher absolute neutrophil count, NLR, platelet-to-lymphocyte ratio (PLR), DNI, C-reactive protein, and symptom duration than uncomplicated cases. ROC analysis showed 85% sensitivity for SII (cutoff 0.84) and NLR (cutoff 3.79) in diagnosing AA. For predicting complications, SII (cutoff 1.71) showed 77.3% sensitivity and 68.4% specificity, while DNI (cutoff 0.055) had the highest specificity (71.1%).</p><p><strong>Conclusion: </strong>Hematological-based indices such as SII, NLR, and DNI are inexpensive and easily accessible markers for diagnosing AA and predicting complications in geriatric patients, although their diagnostic performance differs between outcomes.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"29 7","pages":"812-819"},"PeriodicalIF":0.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative De Ritis Ratio as a Predictor of Adverse Outcomes After Combined Aortic and Mitral Valve Replacement: A Retrospective Cohort Study. 主动脉瓣和二尖瓣联合置换术后的术后肾炎比率作为不良后果的预测指标:一项回顾性队列研究。
IF 0.9 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2026-07-01 Epub Date: 2026-07-30 DOI: 10.4103/njcp.njcp_594_25
T O Badak, D Ucak
{"title":"Postoperative De Ritis Ratio as a Predictor of Adverse Outcomes After Combined Aortic and Mitral Valve Replacement: A Retrospective Cohort Study.","authors":"T O Badak, D Ucak","doi":"10.4103/njcp.njcp_594_25","DOIUrl":"https://doi.org/10.4103/njcp.njcp_594_25","url":null,"abstract":"<p><strong>Background: </strong>Double valve replacement (DVR) of both the aortic and mitral valves is a technically demanding cardiac procedure associated with significant risks, including extended cardiopulmonary bypass times and a pronounced systemic inflammatory response. The De Ritis ratio (aspartate aminotransferase/alanine aminotransferase), a biomarker of cellular injury, has emerged as a prognostic indicator in various clinical scenarios.</p><p><strong>Aim: </strong>The primary objective of this investigation is to elucidate the association between the postoperative De Ritis ratio and the incidence of complications among patients undergoing DVR.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted, encompassing 120 consecutive patients who underwent DVR at our institution between October 2017 and October 2023. The De Ritis ratio was calculated from laboratory values obtained preoperatively and within the first 24 hours postoperatively. Patients were stratified into two groups (postoperative De Ritis ratio ≤1.5 vs. >1.5) to assess its association with adverse outcomes.</p><p><strong>Results: </strong>The mean age of the cohort was 58.2 ± 12.4 years. Patients with a postoperative De Ritis ratio >1.5 experienced a statistically significant prolongation of both their intensive care unit stay (4.8 ± 1.6 days vs. 3.2 ± 1.4 days, P = 0.01) and their overall hospital stay (14.3 ± 4.2 days vs. 9.5 ± 3.1 days, P = 0.008). The 30-day mortality rate was also significantly higher in the elevated De Ritis group (12% vs. 5%, P = 0.04).</p><p><strong>Conclusion: </strong>The postoperative De Ritis ratio independently predicts unfavorable outcomes after DVR. Its integration into routine postoperative risk stratification may enhance surveillance and optimize perioperative management.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"29 7","pages":"757-763"},"PeriodicalIF":0.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Color Stability of Monocrystalline and Polycrystalline Ceramic Orthodontic Brackets Immersed in Coffee Solution: An In Vitro Comparative Study. 单晶和多晶陶瓷正畸托槽在咖啡溶液中的颜色稳定性:体外比较研究。
IF 0.9 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2026-07-01 Epub Date: 2026-07-30 DOI: 10.4103/njcp.njcp_870_25
M A Korayem
{"title":"Color Stability of Monocrystalline and Polycrystalline Ceramic Orthodontic Brackets Immersed in Coffee Solution: An In Vitro Comparative Study.","authors":"M A Korayem","doi":"10.4103/njcp.njcp_870_25","DOIUrl":"https://doi.org/10.4103/njcp.njcp_870_25","url":null,"abstract":"<p><strong>Context: </strong>Appearance of orthodontic appliances significantly influences patients' decisions to undergo orthodontic therapy. As the consumption of coffee stains the orthodontic brackets, an idea to understand the extent of staining between monocrystalline and polycrystalline ceramic orthodontic brackets can be useful in making a better choice.</p><p><strong>Aim: </strong>To compare the color stability of monocrystalline and polycrystalline ceramic brackets on immersion in coffee solution at different time intervals.</p><p><strong>Settings and design: </strong>This interventional comparative study included total of 40 brackets with 20 brackets monocrystalline and polycrystalline each. All the brackets were immersed in a coffee solution, and ∆E values were recorded at 1-hour, 24-hours, 7-days, and 14-days.</p><p><strong>Statistical analysis: </strong>It was performed using SPSS (Statistical Package for Social Sciences) 25.0 version. Between group comparison was done using one-way ANOVA, within group was done using repeated measures ANOVA, and interaction effect of type of bracket and duration of exposure was done using two-way ANOVA.</p><p><strong>Results: </strong>The ∆E was significantly higher for polycrystalline brackets than monocrystalline brackets at all time intervals (1-hour, 24-hours, 7-days, and 14-days). For both monocrystalline and polycrystalline brackets, the ∆E values increased significantly at each subsequent time interval compared to the previous one. Two-way ANOVA revealed that interaction between the effects of type (monocrystalline vs. polycrystalline) of ceramic brackets and duration of exposure had a significant effect on the ∆E.</p><p><strong>Conclusions: </strong>Monocrystalline ceramic brackets exhibit significantly greater color stability. Duration of exposure to coffee has a direct influence on the degree of color change in both types of brackets.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"29 7","pages":"793-797"},"PeriodicalIF":0.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Value of Triglyceride-Glucose (TyG) Index in Predicting Severe Acute Pancreatitis Patients with Acute Pancreatitis in the Emergency Department. 甘油三酯-葡萄糖(TyG)指数对重症急性胰腺炎的预测价值
IF 0.9 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2026-07-01 Epub Date: 2026-07-30 DOI: 10.4103/njcp.njcp_109_26
A Kantar, O Bol, Y Ç Kantar, I Toker, T Aydoğan
{"title":"Value of Triglyceride-Glucose (TyG) Index in Predicting Severe Acute Pancreatitis Patients with Acute Pancreatitis in the Emergency Department.","authors":"A Kantar, O Bol, Y Ç Kantar, I Toker, T Aydoğan","doi":"10.4103/njcp.njcp_109_26","DOIUrl":"10.4103/njcp.njcp_109_26","url":null,"abstract":"<p><strong>Background: </strong>Acute pancreatitis (AP) is an inflammatory disease with an increasing worldwide incidence, ranging from mild edematous forms to severe necrotizing stages. Early prediction of disease severity is vital for guiding treatment strategies.</p><p><strong>Aim: </strong>This study aims to evaluate the value of the Triglyceride-Glucose (TyG) index in predicting disease severity in patients diagnosed with AP in the emergency department.</p><p><strong>Methods: </strong>In this prospective observational study conducted at the Kayseri City Hospital Emergency Department, 165 patients diagnosed with AP between November 15, 2022, and December 15, 2023, were included. Patients were categorized into three groups-mild, moderately severe, and severe AP-according to the Revised Atlanta Classification. The TyG index was calculated using fasting triglyceride and glucose levels at the time of admission.</p><p><strong>Results: </strong>TyG index, glucose, triglyceride, creatinine, and neutrophil-to-lymphocyte ratio (NLR) values were significantly higher in the severe and moderately severe AP groups compared to the mild AP group (p < 0.05). The TyG index was significantly elevated in patients requiring ICU admission and those with systemic inflammatory response syndrome (SIRS) or organ failure. Univariate ordinal regression analysis identified the TyG index as a significant independent predictor of AP severity; each unit increase in the TyG index increased the odds of being in a more severe disease category by 25.58 times (OR: 25.58, 95% CI: 5.43 - 120.55, p < 0.001).</p><p><strong>Conclusion: </strong>The TyG index is a low-cost, easily calculable, and independent metabolic biomarker for predicting disease severity and adverse clinical outcomes in AP patients. Utilizing metabolic indicators like the TyG index alongside inflammatory markers in early risk stratification can be a valuable tool for identifying high-risk patients.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"29 7","pages":"804-811"},"PeriodicalIF":0.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of the Palming Technique on Preoperative Anxiety and Hemodynamic Responses in Thyroid Surgery: A Prospective, Single-Blind, Randomized Controlled Trial. 掌法对甲状腺手术术前焦虑和血流动力学反应的影响:一项前瞻性、单盲、随机对照试验。
IF 0.9 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2026-07-01 Epub Date: 2026-07-30 DOI: 10.4103/njcp.njcp_838_25
M E Toprak, N Yüzkat, N Kurt, H Y Güneş, M E Keskin, C Soyalp
{"title":"Effect of the Palming Technique on Preoperative Anxiety and Hemodynamic Responses in Thyroid Surgery: A Prospective, Single-Blind, Randomized Controlled Trial.","authors":"M E Toprak, N Yüzkat, N Kurt, H Y Güneş, M E Keskin, C Soyalp","doi":"10.4103/njcp.njcp_838_25","DOIUrl":"10.4103/njcp.njcp_838_25","url":null,"abstract":"<p><strong>Aim: </strong>Preoperative anxiety (PA) may adversely affect perioperative management by increasing psychological distress and contributing to hemodynamic fluctuations. This study primarily aimed to evaluate the effect of the palming technique on PA in patients undergoing thyroidectomy and secondarily to examine its influence on perioperative hemodynamic parameters.</p><p><strong>Methods: </strong>A total of 92 patients were initially recruited; after exclusions and withdrawals, 80 American Society of Anesthesiologists I-II patients remained in the final analysis and were allocated to either the palming group ( n = 40) or the control group ( n = 40). Baseline State-Trait Anxiety Inventory (STAI) scores and vital signs, including heart rate (HR), mean arterial pressure (MAP), and peripheral oxygen saturation (SpO₂), were recorded in the preoperative holding area (T1). After a 15-minute interval, during which the palming group performed the palming technique and the control group received standard care, these parameters were reassessed (T2). Hemodynamic measurements were also recorded before induction (T3) and at 1, 3, 5, and 10 minutes after tracheal intubation (T4-T7).</p><p><strong>Results: </strong>At T2, the palming group had significantly lower STAI scores ( P = 0.005), MAP ( P = 0.003), and HR ( P = 0.020) than the control group. STAI scores significantly decreased in the palming group ( P = 0.001), whereas no significant change was observed in controls ( P = 0.647). No significant between-group difference was observed in the hemodynamic response to intubation ( P > 0.05).</p><p><strong>Conclusion: </strong>The palming technique appears to be a feasible, safe, and low-cost nonpharmacological intervention for reducing PA in patients undergoing thyroidectomy. It may also provide favorable short-term effects on preoperative hemodynamic parameters.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"29 7","pages":"786-792"},"PeriodicalIF":0.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148707408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Tranexamic Acid on Visualization Clarity and Bleeding in Shoulder Arthroscopy: A Randomized Controlled Study. 氨甲环酸对肩关节镜观察清晰度和出血的影响:一项随机对照研究。
IF 0.9 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2026-07-01 Epub Date: 2026-07-30 DOI: 10.4103/njcp.njcp_835_25
Y Akalin, F Türkmensoy, F Yesilbursali, F Gozen, N Cevik, A Ozturk
{"title":"Effect of Tranexamic Acid on Visualization Clarity and Bleeding in Shoulder Arthroscopy: A Randomized Controlled Study.","authors":"Y Akalin, F Türkmensoy, F Yesilbursali, F Gozen, N Cevik, A Ozturk","doi":"10.4103/njcp.njcp_835_25","DOIUrl":"10.4103/njcp.njcp_835_25","url":null,"abstract":"<p><strong>Background: </strong>Shoulder arthroscopy has become increasingly popular over the past decade. During this procedure, bleeding directly affects visualization and influences both intraoperative visibility and postoperative outcomes by causing hemarthrosis.</p><p><strong>Aim: </strong>The aim of this study was to investigate the effect of TXA on intraoperative visualization quality through reduction of bleeding.</p><p><strong>Patients and methods: </strong>One hundred and twenty patients were divided into three groups: the intravenous (IV) group received 15 mg/kg of TXA, the local group received 250 mg of TXA added to 3000 cc of irrigation solution, and the placebo group received no TXA administration. During surgery, visualization quality was assessed every 15 minutes as Grade I - poor, Grade II - good, Grade III - excellent. Preoperative and postoperative hemoglobin (Hb) levels, as well as American Shoulder and Elbow Surgeons; Constant; and Disabilities of the Arm, Shoulder, and Hand scores, were recorded. Intraoperative and postoperative blood loss was calculated for all patients.</p><p><strong>Results: </strong>Visualization was significantly better in the groups that received TXA compared to the placebo group, with the IV group demonstrating superior clarity over the local group. Hb loss was lower in the IV group compared to both the local and placebo groups. Intraoperative blood loss was significantly lowest in the IV group, followed by the local group, and highest in the placebo group. All groups showed a significant postoperative improvement in shoulder scores.</p><p><strong>Conclusions: </strong>TXA reduces both intraoperative and postoperative bleeding during shoulder arthroscopy and enhances visualization. Its effects are more pronounced when administered intravenously, as it significantly decreases Hb loss compared to local application and placebo.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"29 7","pages":"780-785"},"PeriodicalIF":0.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148706716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multivariate Evaluation of Risk Factors for Hydrocephalus in Posterior Fossa Tumors. 后窝肿瘤脑积水危险因素的多因素评价。
IF 0.9 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2026-07-01 Epub Date: 2026-07-30 DOI: 10.4103/njcp.njcp_459_25
A Arslan, Z Boga, M E Sarac, S K Olguner, A H Çınkı, F Karaca, Y Gezercan
{"title":"Multivariate Evaluation of Risk Factors for Hydrocephalus in Posterior Fossa Tumors.","authors":"A Arslan, Z Boga, M E Sarac, S K Olguner, A H Çınkı, F Karaca, Y Gezercan","doi":"10.4103/njcp.njcp_459_25","DOIUrl":"https://doi.org/10.4103/njcp.njcp_459_25","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to fully analyze the hydrocephalus risk factors according to tumor characteristics and treatment protocols and their effects on patient survival.</p><p><strong>Material and methods: </strong>We retrospectively analyzed 31 patients (13 pontine gliomas, 18 cerebellar metastases) treated from January 2019 to January 2024. The preoperative and postoperative magnetic resonance images provided volumetric measurements to determine tumor characteristics including volume and fourth ventricle distance and ventricular configuration. The treatment plan for pontine glioma patients included 50.4 Gy (1.8 Gy/fraction), while metastasis patients received 30 Gy whole-brain radiotherapy with a 9 Gy boost to the tumor bed (total 39 Gy). The analysis used univariate and multivariate Cox proportional hazards regression models to examine the relationships between tumor characteristics and hydrocephalus development as a time-to-event outcome and survival.</p><p><strong>Results: </strong>The mean tumor volumes were 24.7 ± 5.8 cm 3 (pontine gliomas) and 17.3 ± 6.2 cm 3 (metastases), with mean fourth-ventricle distances of 1.58 ± 0.72 cm and 2.34 ± 0.81 cm, respectively. Hydrocephalus developed in 30.8% of pontine glioma patients and 27.8% of metastasis patients ( P > 0.05). Multivariate Cox proportional hazards regression analysis revealed increased hydrocephalus risk with a tumor volume >20 cm 3 (hazard ratio (HR) =3.86, 95% CI: 1.92-7.74) a fourth-ventricle distance ≤2 cm (HR = 3.42, 95% CI: 1.68-6.96), and distorted ventricular configuration (HR = 3.28, 95% CI: 1.62-6.64). Ventricle configuration distortion predominated in pontine gliomas (75% of hydrocephalus cases), while ventricle proximity predominated in metastases (80% of cases). Radiotherapy doses had no significant effect on hydrocephalus rates (HR = 1.14, 95% CI: 0.72-1.82, P = 0.568).</p><p><strong>Conclusions: </strong>The development of hydrocephalus in posterior fossa tumors seems to be more closely related to the anatomical features of the tumor than to the doses of radiotherapy. Hydrocephalus has a negative impact on survival outcomes.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"29 7","pages":"741-748"},"PeriodicalIF":0.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148706692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Menstrual Blood as Stem Cell Potential: The Turkish Example. 经血作为干细胞的潜力:土耳其的例子。
IF 0.9 4区 医学
Nigerian Journal of Clinical Practice Pub Date : 2026-07-01 Epub Date: 2026-07-30 DOI: 10.4103/njcp.njcp_512_25
I Unal, A Akan, G Kardeş, N Duman, H Aydemir, A Hadımlı, H O Can
{"title":"Menstrual Blood as Stem Cell Potential: The Turkish Example.","authors":"I Unal, A Akan, G Kardeş, N Duman, H Aydemir, A Hadımlı, H O Can","doi":"10.4103/njcp.njcp_512_25","DOIUrl":"https://doi.org/10.4103/njcp.njcp_512_25","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed at determining the opinions of midwifery students studying at several universities in Turkey regarding menstrual blood donation.</p><p><strong>Methods: </strong>The population of this cross-sectional study consisted of midwifery students enrolled in undergraduate programs at several universities in Turkey during the 2023-2024 academic year. Of the 15,689 students, 1346 were reached. Data were collected online using a questionnaire developed by the researchers based on a literature review. The questionnaire comprised two sections: a 10-item questioning Descriptive Information Form assessing sociodemographic characteristics and a 21-item form evaluating participants' knowledge of menstrual blood donation. Data were analyzed using number-percentage distributions and the Chi-square test.</p><p><strong>Results: </strong>Among the participating midwifery students, 50% perceived menstruation as a positive process. Only 8.2% were aware that menstrual blood contains stem cells, and 1.2% knew that menstrual blood can be donated for stem cell use. Similarly, awareness of menstrual blood banking was low (2.6%).</p><p><strong>Conclusion: </strong>Midwifery students in Turkey have limited awareness and knowledge regarding menstrual blood and its stem cell potential. Improving perceptions of menstruation and promoting positive attitudes may enhance knowledge levels and contribute to raising awareness in society.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"29 7","pages":"749-756"},"PeriodicalIF":0.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148706714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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