{"title":"Assessment of Normal Pancreatic Stiffness Using 3T Magnetic Resonance Elastography.","authors":"L Karakaş, S Poçan, A Y Karkaş, Ş Şahin","doi":"10.4103/njcp.njcp_192_25","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This study aimed to establish the normal range of pancreatic stiffness in adults using 3T magnetic resonance elastography (MRE) and investigate how factors such as age, sex, pancreatic diameter, and anthropometric characteristics influence pancreatic stiffness.</p><p><strong>Aim: </strong>We aimed to provide data to the literature in determining the stiffness values of normal pancreatic tissue with 3T MRE.</p><p><strong>Methods: </strong>Patient demographic data, including age, sex, and body mass index (BMI), were collected. magnetic resonance imaging (MRI) and MRE parameters were extracted from the hospital's radiology database. Medical history, including liver or pancreatic conditions, was obtained from the patients and confirmed through electronic medical records.</p><p><strong>Results: </strong>The study included 54 patients, comprising 31 males (57.4%) and 23 females (42.6%), with a mean age of 35.8 ± 9.18 years. The average BMI was 24.73 ± 1.83 kg/m². The pancreatic diameters were 20.80 ± 2.13 cm (CC) and 19.93 ± 3.29 cm (AP). The mean pancreatic stiffness was 1587.09 ± 114.90 Pascals (Pa). No significant correlations were found between pancreatic stiffness and age (r = -0.128, P = 0.358), sex (r = -0.051, P = 0.716), BMI (r = -0.026, P = 0.850), pancreatic CC diameter (r = -0.090, P = 0.519), or AP diameter (r = 0.054, P = 0.701).</p><p><strong>Conclusion: </strong>This study provides reliable baseline values for normal pancreatic stiffness (1587.09 ± 114.90 Pa) using 3T MRE, which is essential for distinguishing normal from pathological tissue. These findings suggest that demographic and anatomical factors have little impact on pancreatic stiffness, supporting the potential of MRE in evaluating pancreatic diseases.</p>","PeriodicalId":19431,"journal":{"name":"Nigerian Journal of Clinical Practice","volume":"28 6","pages":"751-757"},"PeriodicalIF":0.7000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nigerian Journal of Clinical Practice","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4103/njcp.njcp_192_25","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/25 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background: This study aimed to establish the normal range of pancreatic stiffness in adults using 3T magnetic resonance elastography (MRE) and investigate how factors such as age, sex, pancreatic diameter, and anthropometric characteristics influence pancreatic stiffness.
Aim: We aimed to provide data to the literature in determining the stiffness values of normal pancreatic tissue with 3T MRE.
Methods: Patient demographic data, including age, sex, and body mass index (BMI), were collected. magnetic resonance imaging (MRI) and MRE parameters were extracted from the hospital's radiology database. Medical history, including liver or pancreatic conditions, was obtained from the patients and confirmed through electronic medical records.
Results: The study included 54 patients, comprising 31 males (57.4%) and 23 females (42.6%), with a mean age of 35.8 ± 9.18 years. The average BMI was 24.73 ± 1.83 kg/m². The pancreatic diameters were 20.80 ± 2.13 cm (CC) and 19.93 ± 3.29 cm (AP). The mean pancreatic stiffness was 1587.09 ± 114.90 Pascals (Pa). No significant correlations were found between pancreatic stiffness and age (r = -0.128, P = 0.358), sex (r = -0.051, P = 0.716), BMI (r = -0.026, P = 0.850), pancreatic CC diameter (r = -0.090, P = 0.519), or AP diameter (r = 0.054, P = 0.701).
Conclusion: This study provides reliable baseline values for normal pancreatic stiffness (1587.09 ± 114.90 Pa) using 3T MRE, which is essential for distinguishing normal from pathological tissue. These findings suggest that demographic and anatomical factors have little impact on pancreatic stiffness, supporting the potential of MRE in evaluating pancreatic diseases.
背景：本研究旨在通过3T磁共振弹性成像（MRE）建立成人胰腺硬度的正常范围，并探讨年龄、性别、胰腺直径和人体测量特征等因素对胰腺硬度的影响。目的：我们的目的是为用3T磁共振成像确定正常胰腺组织的刚度值提供文献资料。方法：收集患者人口统计资料，包括年龄、性别、体重指数（BMI）。从医院的放射学数据库中提取磁共振成像（MRI）和磁共振成像（MRE）参数。从患者那里获得病史，包括肝脏或胰腺疾病，并通过电子病历进行确认。结果：共纳入54例患者，其中男性31例（57.4%），女性23例（42.6%），平均年龄35.8±9.18岁。平均BMI为24.73±1.83 kg/m²。胰腺直径分别为20.80±2.13 cm （CC）和19.93±3.29 cm （AP）。平均胰腺僵硬度为1587.09±114.90帕斯卡（Pa）。胰腺硬度与年龄（r = -0.128, P = 0.358）、性别（r = -0.051, P = 0.716）、BMI （r = -0.026, P = 0.850）、胰腺CC直径（r = -0.090, P = 0.519）、AP直径（r = 0.054, P = 0.701）无显著相关性。结论：本研究提供了可靠的3T MRE正常胰腺刚度基线值（1587.09±114.90 Pa），这是区分正常组织和病理组织的必要条件。这些结果表明，人口统计学和解剖学因素对胰腺硬度的影响很小，支持MRE在评估胰腺疾病方面的潜力。
期刊介绍：
The Nigerian Journal of Clinical Practice is a Monthly peer-reviewed international journal published by the Medical and Dental Consultants’ Association of Nigeria. The journal’s full text is available online at www.njcponline.com. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository. The journal makes a token charge for submission, processing and publication of manuscripts including color reproduction of photographs.
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