Neuroradiology最新文献

{"title":"Jugular bulb ASL-MRI hyperintensity and severe internal jugular vein stenosis: a potential pitfall in neuroimaging.","authors":"Thomas R Geisbush, Siddhant S Dhawan, Periakaruppan V Manickam, Tarik F Massoud","doi":"10.1007/s00234-025-03623-z","DOIUrl":"10.1007/s00234-025-03623-z","url":null,"abstract":"<p><p>Incidental artifactual MRI arterial spin-labeling (ASL-MRI) hyperintense signal at the left jugular bulb (JB-ASL[+]) often creates a neurodiagnostic dilemma because of potential misinterpretation as a dural arteriovenous fistula. JB-ASL(+) likely follows 'benign jugular venous reflux' but an additional contribution to signal genesis owing to styloidogenic jugular venous compression (SJVC) has not been evaluated previously. We studied the link between SJVC percentage stenosis of internal jugular veins (IJVs) and JB-ASL(+) signal intensity by retrospectively reviewing MRIs of 30 JB-ASL(+) patients and 30 age and sex-matched JB-ASL(-) controls. In JB-ASL(+) patients, we found a significantly higher percent increase in ASL-MRI hyperintensity with severe (> 75% IJV stenosis) versus non-severe SJVC (p = 0.026). Thus, in some patients, accentuation of JB-ASL(+) signal conceivably occurs after retrograde trapping of labeled venous blood proximal to a severe SJVC. Presence of severe SJVC represents a novel contributory factor in understanding JB-ASL(+) as a clinically problematic source of neuroimaging misdiagnosis.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2015-2018"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between movement impairments and glymphatic system dysfunction in spastic diplegic cerebral palsy using DTI-ALPS.","authors":"Mengyi Wang, Xiaochen Jiang, Binbin Nie, Han Meng, Hao Song, Ying Liu, Jiqiang Liu, Xuetao Mu","doi":"10.1007/s00234-025-03628-8","DOIUrl":"10.1007/s00234-025-03628-8","url":null,"abstract":"<p><strong>Background: </strong>The role of the glymphatic system in occult cerebral palsy (CP) remains unclear. In this study, glymphatic system function and its association with motor impairment in occult CP patients was investigated using diffusion tensor image analysis along the perivascular space (DTI-ALPS).</p><p><strong>Methods: </strong>This retrospective study used DTI to calculate the diffusivity values along the x-, y-, and z-axes in 27 occult CP patients and 27 matched controls. A correlation analysis the ALPS index, derived from perivascular, projection, and association fibres, and with the Gross Motor Function Classification (GMFSC) grade was performed.</p><p><strong>Results: </strong>We found significant differences in the ALPS index between occult CP patients and healthy controls (HCs). The ALPS index of the lateral hemisphere was lower in occult CP patients than in HCs (left: 1.51 ± 0.20 vs. 1.68 ± 0.24, p = 0.011; right: 1.51 ± 0.20 vs. 1.65 ± 0.24, p = 0.019). Correlation analysis revealed a negative correlation between the ALPS index in the lateral hemisphere and the GMFSC grade (left: r = -0.61, p = 0.004; right: r = -0.48, p = 0.015).</p><p><strong>Conclusion: </strong>Our findings show that occult CP patients have reduced ALPS indices, suggesting glymphatic system dysfunction. Lower ALPS indices were associated with higher motor function grades, indicating a potential link between glymphatic system dysfunction and motor impairment in CP patients.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2097-2106"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Considerations regarding the morphological variability of the superior cerebellar artery.","authors":"Panagiotis Papadopoulos-Manolarakis, George Triantafyllou, Panagiotis Papanagiotou, George Tsakotos, Evangelia Christodoulou, Maria Piagkou","doi":"10.1007/s00234-025-03659-1","DOIUrl":"10.1007/s00234-025-03659-1","url":null,"abstract":"","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"1997-2004"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medium vessel occlusions and endovascular treatment: what's next??","authors":"Senta Frol, Wim H van Zwam, Adnan H Siddiqui, René Chapot","doi":"10.1007/s00234-025-03712-z","DOIUrl":"10.1007/s00234-025-03712-z","url":null,"abstract":"","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"1967-1970"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Jugular bulb ASL-MRI hyperintensity and severe internal jugular vein stenosis: a potential pitfall in neuroimaging.","authors":"Thomas R Geisbush, Siddhant S Dhawan, Periakaruppan V Manickam, Tarik F Massoud","doi":"10.1007/s00234-025-03639-5","DOIUrl":"10.1007/s00234-025-03639-5","url":null,"abstract":"","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2019"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing anemia in stroke patients through virtual non-contrast imaging with photon-counting detector CT: validation on supra-aortic vessel CT-Angiography.","authors":"Guilherme A Quint, Josua A Decker, Abraham Cortes, Ansgar Berlis, Christoph J Maurer","doi":"10.1007/s00234-025-03620-2","DOIUrl":"10.1007/s00234-025-03620-2","url":null,"abstract":"<p><strong>Background and purpose: </strong>Anemia is a common comorbidity in stroke patients, traditionally detected via blood tests. This study evaluates the feasibility of using virtual non-contrast (VNC) imaging from photon counting detector-CT (PCD-CT) angiography to detect anemia and identifies the optimal anatomical site for assessment.</p><p><strong>Materials and methods: </strong>In this retrospective study of 80 patients undergoing PCD-CT angiography of supra-aortic vessels, VNC series were analyzed at various anatomical sites, including the jugular veins, aorta, and cerebral sinuses. Correlations between serum hemoglobin (Hb) levels and VNC Hounsfield Unit (HU) values were assessed using Pearson's coefficients. Linear regression and ROC analysis evaluated diagnostic performance.ResultsThe jugular veins showed the strongest correlation between VNC HU values and Hb levels (R² = 0.49, p < 0.001), with weaker correlations in arterial vessels like the aorta (R² = 0.11, p < 0.001). ROC analysis of jugular vein VNC values yielded an AUC of 0.79 for anemia detection. Correlation strength declined with longer intervals between imaging and blood tests, suggesting temporal Hb variability.</p><p><strong>Conclusions: </strong>VNC imaging in CT angiography is a feasible method for detecting anemia, with the jugular veins providing the most reliable site for assessment. VNC imaging could be a valuable alternative when blood tests are delayed or unavailable.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2031-2039"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disrupted static and dynamic Large-scale brain functional network connectivity in the differentiation of myelin oligodendrocyte glycoprotein Antibody-Seropositive from seronegative optic neuritis.","authors":"Wentao Wang, Xilan Liu, Yan Sha, Ximing Wang, Ping Lu","doi":"10.1007/s00234-025-03643-9","DOIUrl":"10.1007/s00234-025-03643-9","url":null,"abstract":"<p><strong>Purpose: </strong>The ability to distinguish myelin oligodendrocyte glycoprotein antibody-seropositive optic neuritis (MOG-ON) from seronegative-ON is critical in clinical practice. We investigate potential neural mechanisms and differentiation biomarkers via large-scale functional network connectivity (FNC) using resting-state functional magnetic resonance imaging (RS-fMRI).</p><p><strong>Methods: </strong>RS-fMRI-based independent component analysis (ICA) was performed in 79 subjects, including 23 with MOG-ON, 30 with seronegative-ON and 26 healthy controls (HCs). The resting-state networks (RSNs) extracted from the ICA were used to investigate static FNC (sFNC) changes within and between groups. In addition, 5 dynamic FNC (dFNC) states were identified using k-means cluster analysis, and several state-related properties were calculated. Receiver operating characteristic (ROC) curve analysis was also performed to determine its value in differential diagnosis.</p><p><strong>Results: </strong>In the sFNC analysis, the patient groups showed decreased intranetwork functional connectivity (FC) within several RSNs compared to the HC group. The MOG-ON group presented significantly altered intranetwork FC in the medial visual network (mVN) and posterior default mode network (pDMN) compared with the seronegative-ON group. Compared with the HCs, the patient groups also presented abnormal internetwork FC between RSNs. In the dFNC analysis, the patient groups presented altered fractional occupancy and dwell times in states 1 and 5 compared with HCs, and the changes in state-related metrics were also distinct between the MOG-ON and seronegative-ON groups. In terms of ROC curve analysis, optimal diagnostic performance was achieved by combining static and dynamic approaches.</p><p><strong>Conclusions: </strong>Abnormal large-scale static and dynamic brain functional networks may help to better understand the neural mechanisms of MOG-ON and seronegative-ON and their differentiation.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2107-2119"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal duration of dual antiplatelet therapy after endovascular treatment of intracranial aneurysms with stenting: a systematic review and meta-analysis.","authors":"Anderson Matheus Pereira da Silva, Ocílio de Deus, Luciano Falcão, Mariana Lee Han, Filipe Virgilio Ribeiro, Pedro Lucas Machado Magalhães, Altair Melo Neto, Othon Trevisan Meira, Mariana Leticia Bastos Maximiano, Gustavo Sousa Noleto, Ahmet Günkan, Pascal M Jabbour","doi":"10.1007/s00234-025-03710-1","DOIUrl":"https://doi.org/10.1007/s00234-025-03710-1","url":null,"abstract":"<p><strong>Background: </strong>The optimal duration of dual antiplatelet therapy (DAPT) following endovascular treatment of intracranial aneurysms remains uncertain. While DAPT effectively prevents thromboembolic complications, prolonged therapy may increase bleeding risk. This systematic review and meta-analysis compared the efficacy and safety of short-term versus long-term DAPT in patients undergoing endovascular treatment with stent-assisted coiling or flow diversion.</p><p><strong>Methods: </strong>We conducted a systematic review and meta-analysis according to PRISMA guidelines. Studies were identified through PubMed, Embase and Cochrane from inception to January 2025. Eligible studies included randomized controlled trials (RCTs) and observational cohorts comparing short-term DAPT (≤ 6 months) with long-term DAPT (> 6 months) in adults treated for intracranial aneurysms. Pooled risk ratio (RR) with 95% confidence intervals (CI) were calculated using a random-effects model. Risk of bias was assessed using RoB 2 for RCTs and ROBINS-I for observational studies.</p><p><strong>Results: </strong>Seven studies, comprising a total of 17,380 patients, were included, one RCT and six retrospective cohorts. The pooled analysis showed no significant difference in thromboembolic events between short- and long-term DAPT (RR: 1.18; 95% CI: 0.42-3.30; I² = 60.5%). Short-term DAPT was associated with a lower risk of major bleeding (RR: 0.54; 95% CI: 0.32-0.91; I² = 0%). No significant differences were observed between groups in retreatment (RR: 0.94; 95% CI: 0.24-3.62) or mortality (RR: 3.11; 95% CI: 0.96-10.09).</p><p><strong>Conclusions: </strong>Short-term DAPT demonstrates similar efficacy to long-term DAPT in preventing thromboembolic events and retreatment, with a lower incidence of major bleeding. These findings suggest that shorter DAPT regimens may offer a favorable safety profile. However, further large-scale RCTs are needed to establish definitive guidelines.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of large vessel occlusion using artificial intelligence tools: A systematic review and meta-analysis.","authors":"Julyana Dantas, Giovana Barros, Antonio Mutarelli, Caroline Dagostin, Pedro Romeiro, Giulia Almirón, Nicole Felix, Agostinho Pinheiro, Matheus A Bannach","doi":"10.1007/s00234-025-03716-9","DOIUrl":"https://doi.org/10.1007/s00234-025-03716-9","url":null,"abstract":"<p><strong>Background and purpose: </strong>Large vessel occlusion (LVO) accounts for a third of all ischemic strokes. Artificial intelligence (AI) has shown good accuracy in identifying LVOs on computed tomography angiograms (CTA). We sought to analyze whether AI-adjudicated CTA improves workflow times and clinical outcomes in patients with confirmed LVOs.</p><p><strong>Materials and methods: </strong>We systematically searched PubMed, Embase, and Web of Science for studies comparing initial radiological assessment assisted by AI softwares versus standard assessment of patients with acute LVO strokes. Results were pooled using a random-effects model as mean differences for continuous outcomes or odds ratio (OR) for dichotomous outcomes, along with 95% confidence intervals (CI).</p><p><strong>Results: </strong>We included 9 studies comprising 1,270 patients, of whom 671 (52.8%) had AI-assisted radiological assessment. AI consistently improved treatment times when compared to standard assessment, as evidenced by a mean reduction of 20.55 minutes in door-to-groin time (95% CI -36.69 to -4.42 minutes; p<0.01) and a reduction of 14.99 minutes in CTA to reperfusion (95% CI -28.45 to -1.53 minutes; p=0.03). Functional independence, defined as a modified Rankin scale 0-2, occurred at similar rates in the AI-supported group and with the standard workflow (OR 1.27; 95% CI 0.92 to 1.76; p=0.14), as did mortality (OR 0.71; 95% CI 0.27 to 1.88; p=0.49).</p><p><strong>Conclusions: </strong>The incorporation of AI softwares for LVO detection in acute ischemic stroke enhanced workflow efficiency and was associated with decreased time to treatment. However, AI did not improve clinical outcomes as compared with standard assessment.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144743365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cortical venous opacification score predicts outcomes after thrombectomy in large vessel occlusion stroke: a systematic review and meta-analysis.","authors":"Rafaela Correia Maciel, Wei Jun Lee, Beatriz Aguiar de Macedo, Davi Barbosa Pereira da Silva, Amanda Boutrik, Maria Clara Merighi, Henrique Alexsander Ferreira Neves, Luisa Braga Salles Machado, Bernard Giancristoforo Campos","doi":"10.1007/s00234-025-03701-2","DOIUrl":"https://doi.org/10.1007/s00234-025-03701-2","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to assess whether the Cortical Vein Opacification Score (COVES), a visual scoring system based on single-phase Computed Tomography Angiography (CTA), is associated with clinical and radiological outcomes in patients with acute ischemic stroke due to large vessel occlusion (AIS-LVO) after endovascular treatment (EVT).</p><p><strong>Methods and materials: </strong>A systematic review and meta-analysis were conducted according to PRISMA guidelines. PubMed, EMBASE, and Cochrane Library were searched from inception to early June 2025, identifying 572 articles, of which 6 were included. Post-hoc analyses of randomized controlled trials (RCTs) and observational studies, with patients stratified by venous outflow (VO) status, were included. Pooled risk ratios (RRs) with 95% confidence intervals (CIs) were calculated using a random-effects model. Heterogeneity was assessed using I² statistic. Sensitivity analyses were performed in outcomes that presented high heterogeneity.</p><p><strong>Results: </strong>The six studies included 2,709 patients. VO + was associated with higher excellent (RR 1.34; p < 0.001) and successful reperfusion (RR 1.05; p = 0.001). Functional independence at 90 days (modified Rankin Scale [mRS] 0-2) was higher in the VO + group (RR 2.67; p = 0.002). VO + was associated with lower rates of symptomatic intracranial hemorrhage (sICH), parenchymal hematoma (PH), and mortality at 90 days.</p><p><strong>Conclusion: </strong>VO + is associated with better reperfusion and functional independence, as well as reduced hemorrhagic complications and mortality. These findings support the potential prognostic value of VO in AIS-LVO patients undergoing EVT. Heterogeneity and limited number of studies warrant cautious interpretation. Standardized imaging protocols and prospective validation are needed.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144743364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}