Neuroradiology最新文献

{"title":"European Society of Neuroradiology (ESNR).","authors":"","doi":"10.1007/s00234-025-03824-6","DOIUrl":"https://doi.org/10.1007/s00234-025-03824-6","url":null,"abstract":"","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145355584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety of mechanical thrombectomy in pediatric acute ischemic stroke: a systematic review and meta-analysis.","authors":"Lucca Tamara Alves Carretta, Ocilio Ribeiro Gonçalves, Lucas Copolillo Faria, Rafael Torres Fonseca Dos Santos, Mariana Lee Han, Wagner Rios-Garcia, Filipe Virgilio Ribeiro, Marianna Leite, Yasmin Picanço Silva, Adil Ahmed, Nicole Baptista de Oliveira, Ahmet Günkan, Pascal Jabbour","doi":"10.1007/s00234-025-03814-8","DOIUrl":"https://doi.org/10.1007/s00234-025-03814-8","url":null,"abstract":"<p><strong>Purpose: </strong>This meta-analysis aimed to evaluate the clinical outcomes and safety of mechanical thrombectomy (MT) in pediatric acute ischemic stroke (AIS).</p><p><strong>Methods: </strong>Systematic search of PubMed, Embase and Cochrane Library identified studies on MT in children (≤ 18 years) with AIS. Data on baseline characteristics, procedural details and clinical outcomes, including favorable functional outcome (modified Rankin Scale [mRS] 0-2), National Institutes of Health Stroke Scale (NIHSS) reduction, Pediatric Stroke Outcome Measure (PSOM), symptomatic intracranial hemorrhage (sICH) and mortality were extracted. A single-arm meta-analysis was performed to estimate pooled rates.</p><p><strong>Results: </strong>25 studies, encompassing 885 patients (mean age of included cohorts: 10.2-18 years), were included. The pooled favorable functional outcome was 80% (95% CI, 70%-88%), while the poor functional outcome was 14% (95% CI: 5%-26%). Mean NIHSS reduction was 8.07 (95% CI, 5.93-10.22), PedNIHSS decrease was 14.64 (95% CI: 12.04 to 17.24), and pooled mean PSOM score at follow-up was 1.02 (95% CI, 0.48-1.55). sICH was 2% (95% CI, 0-5%), need for decompressive hemicraniectomy was 7% (95% CI: 2%-14%) and overall mortality was 4% (95% CI, 1%-8%). Successful recanalization was 88% (95% CI: 81%-95%) and no reperfusion and re-occlusion were both 3% (95% CI: 0%-7%).</p><p><strong>Conclusion: </strong>MT appears to be a promising and safe treatment option for pediatric AIS, demonstrating high rates of favorable functional outcomes and low mortality/sICH. However, significant heterogeneity among studies highlights the need for further high-quality, standardized research to optimize patient selection and define its effectiveness.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145346069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A predictive model for differentiating PFA and PFB subtypes of posterior fossa ependymoma using multi-sequence MRI radiomics: a two-center study.","authors":"Rui Xu, Hanjiaerbieke Kukun, Jing Xue, Yuhui Xiong, Wei Zhao, Yuwei Xia, Yangyang Li, Pahati Tuxunjiang, Chunhui Jiang, Wenyu Ji, Yunling Wang, Hu Xiao","doi":"10.1007/s00234-025-03823-7","DOIUrl":"https://doi.org/10.1007/s00234-025-03823-7","url":null,"abstract":"","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145346106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pituitary neuroendocrine tumor: evaluation with super resolution deep learning reconstruction : Research.","authors":"Koichiro Yasaka, Akira Katayama, Naoya Sakamoto, Yuko Sato, Yusuke Asari, Jun Kanzawa, Yuki Sonoda, Yuichi Suzuki, Shiori Amemiya, Shigeru Kiryu, Osamu Abe","doi":"10.1007/s00234-025-03819-3","DOIUrl":"https://doi.org/10.1007/s00234-025-03819-3","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the impact of super-resolution deep learning reconstruction (SR-DLR) algorithm on the evaluations of pituitary neuroendocrine tumor (PitNET) and on the image quality of pituitary MRI compared to conventional images with zero-filling interpolation (ZIP) technique.</p><p><strong>Methods: </strong>This retrospective study included 29 patients with PitNET who underwent pituitary MRI imaging. T2-weighted coronal images were reconstructed with SR-DLR and ZIP. Three readers assessed the images in terms of pituitary stalk deviation, noise, sharpness, depiction of PitNET, and diagnostic acceptability. A radiologist placed circular or ovoid regions of interest (ROIs) on the lateral ventricle and the tumor, and signal-to-noise ratio (SNR) and contrast-to-noise ratio were calculated. The radiologist also placed a linear ROI crossing the septum pellucidum perpendicularly. From the signal intensity profile along this ROI, edge rise slope (ERS) and full width at half maximum (FWHM) were calculated.</p><p><strong>Results: </strong>Inter-reader agreement in the evaluations of pituitary stalk deviation in SR-DLR (0.518) tended to be superior to that in ZIP (0.405). Scores in the qualitative image analyses in SR-DLR were significantly better than those in ZIP for all evaluation items (p < 0.001). SNR and CNR in SR-DLR were significantly higher compared to ZIP (p < 0.001). Results of ERS (5433/2177 in SR-DLR/ZIP) and FWHM (0.67/1.27 mm in SR-DLR/ZIP) indicated significantly enhanced spatial resolution in SR-DLR compared to ZIP.</p><p><strong>Conclusion: </strong>SR-DLR tended to enhance inter-reader agreement in the evaluations of pituitary stalk deviation and significantly improved quality of pituitary MRI images compared to conventional ZIP images.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145337398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved detection of spinal cord lesions using an axial T2-weighted TSE sequence with full spinal cord coverage compared to sagittal T2-weighted TSE and STIR sequences in multiple sclerosis: a prospective study.","authors":"Christian Thaler, Vincent Geest, Lukas Meyer, Charlotte Schubert, Christoph Heesen, Jens Fiehler, Susanne Gellißen","doi":"10.1007/s00234-025-03813-9","DOIUrl":"https://doi.org/10.1007/s00234-025-03813-9","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare the detection rates and inter-rater agreements of the sagittal T2w-TSE and sagittal short tau inversion recovery (STIR) sequence versus the axial T2w-TSE sequence with full spinal cord coverage in identifying spinal cord lesions in patients with suspected demyelinating diseases and diagnosed multiple sclerosis (MS).</p><p><strong>Methods: </strong>104 patients were prospectively enrolled in this study and underwent MRI, including a sagittal T2w-TSE and STIR sequence, as well as an axial T2w-TSE sequence with full spinal cord coverage. Two experienced neuroradiologists, blinded to clinical parameters, independently evaluated the scans in separate sessions. After blinded readings, raters re-evaluated all sequences to assess if lesions could be retrospectively identified in other sequences.</p><p><strong>Results: </strong>Spinal cord lesions were found in 81 patients. The highest inter-rater reliability was observed for the sagittal T2w-TSE sequence (κ = 0.73, 95%-CI 0.66-0.79), followed by the axial T2w-TSE (κ = 0.71, 95%-CI 0.63-0.79) and the sagittal STIR sequence (κ = 0.65, 95%-CI 0.58-0.73). The axial T2w-TSE sequence demonstrated superior lesion detection rates, identifying significantly more lesions (n = 361) compared to the STIR (n = 293) and T2w-TSE sagittal (n = 224) sequence (p < 0.001).</p><p><strong>Conclusion: </strong>Axial T2w-TSE sequences with full spinal cord coverage provide superior lesion detection compared to sagittal sequences and should be included in standard MRI protocols for MS patients. They may accelerate meeting MRI criteria for MS, improve monitoring of disease progression, and enhance prediction of future disability.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145337387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational radiation exposure of radiologic technologists in Interventional neuroradiology.","authors":"Anna Beckert, Christopher Kloth, Angela Kretschmer, Bernd Schmitz, Johannes Rosskopf","doi":"10.1007/s00234-025-03807-7","DOIUrl":"https://doi.org/10.1007/s00234-025-03807-7","url":null,"abstract":"<p><strong>Purpose: </strong>With the rising number of angiographic interventional procedures, occupational radiation exposure is becoming increasingly relevant. As even low doses may contribute to stochastic health effects, enhanced radiological protection measures are warranted. This study aimed to systematically quantify the radiation exposure of radiologic technologists under routine clinical conditions and in an experimental setting.</p><p><strong>Methods: </strong>Radiation dose exposure was monitored over one month using three official dosimeters placed at defined locations within the angiography suite, using the floor-mounted C-arm as a reference point. Dose values were extrapolated to estimate annual exposure. Additionally, experimental dose rate measurements were performed at eight locations and three height levels (foot, torso, eye) under standardized conditions using both standard and low-dose DSA protocols.</p><p><strong>Results: </strong>Official dosimeter readings averaged less than 2% of the reference value at the C-arm. The extrapolated annual occupational radiation exposure was low (0.44 mSv), with the highest value of 1.03 mSv near the door to the supply room. Experimental measurements revealed average radiation dose rates of 885 µSv/h; with a wide range from: 12 to 6109 µSv/h. Dose rates were more strongly influenced by the shielding effect of stationary protective equipment (reduction factor of 31) than by spatial distance. The highest radiation exposure occurred at foot level. Low-dose protocols reduced ambient radiation by an average of 23%.</p><p><strong>Conclusion: </strong>Occupational exposure remained well below legal thresholds but varied spatially. Stationary shielding and low-dose protocols proved most effective for dose reduction.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145308749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal evolution of non-contrast CT markers of expansion relates to the dynamics of acute intracerebral hemorrhage.","authors":"David Rodriguez-Luna, Olalla Pancorbo, João André Sousa, Renato Simonetti, Pilar Coscojuela, Marc Rodrigo-Gisbert, Federica Rizzo, Marta Olivé-Gadea, Manuel Requena, Álvaro García-Tornel, Noelia Rodriguez-Villatoro, Jesús M Juega, Marián Muchada, Jorge Pagola, Marta Rubiera, Marc Ribo, Alejandro Tomasello, Carlos A Molina","doi":"10.1007/s00234-025-03789-6","DOIUrl":"https://doi.org/10.1007/s00234-025-03789-6","url":null,"abstract":"<p><strong>Purpose: </strong>The temporal evolution of non-contrast CT (NCCT) markers of intracerebral hemorrhage (ICH) expansion during the dynamics of acute ICH is understudied. We aimed to evaluate the temporal evolution of these markers and its relationship with ICH dynamics.</p><p><strong>Methods: </strong>Single-center, prospective, observational cohort study on 271 ICH patients < 6 h. Patients underwent baseline NCCT and multiphase CTA, and 24-hour NCCT. NCCT markers included: irregular shape, satellite sign, and island sign (shape markers); heterogeneous density, hypodensities, swirl sign, black hole sign, blend sign, and fluid level (qualitative density markers); and mean, standard deviation, and coefficient of variation hematoma density (quantitative density markers). The spot sign in first phase of multiphase CTA was considered marker of active hemorrhage. Primary outcome was the change in frequency or values of NCCT markers from baseline to follow-up NCCT. Other outcomes included associations of active hemorrhage with NCCT markers at baseline and with the magnitude of their change at follow-up NCCT.</p><p><strong>Results: </strong>Heterogeneous density predicted active hemorrhage with the highest accuracy (66.4%); hypodensities had the highest AUC (0.626, 95% CI 0.561-0.691). From baseline to follow-up NCCT, the frequency of heterogeneous density (54 [27.8%] vs. 24 [12.4%], p < 0.001) and hypodensities (82 [42.3%] vs. 52 [26.8%], p < 0.001) decreased, with greater reductions when active hemorrhage at baseline (17 [29.0%] vs. 12 [10.0%], p = 0.001; and 15 [26.3%] vs. 13 [10.8%], p = 0.008; respectively).</p><p><strong>Conclusion: </strong>Heterogeneous density and hypodensities are the markers most closely related to acute ICH dynamics, better predicting active hemorrhage at baseline and decreasing with hematoma stabilization.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145308740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of middle meningeal artery embolization combined with surgery versus standalone surgery for chronic subdural hematoma: a comprehensive systematic review and Meta-Analysis with separate analysis of randomized controlled trials.","authors":"Ibrahim Mohammadzadeh, Bardia Hajikarimloo, Amirhossein Zare, Shahin Mohammadzadeh, Pooya Eini, Saba Aghajani, Ali Mortezaei, Mohammad Amin Habibi, Kivanc Yangi, Ahmet Günkan, Pascal Jabbour","doi":"10.1007/s00234-025-03777-w","DOIUrl":"https://doi.org/10.1007/s00234-025-03777-w","url":null,"abstract":"<p><strong>Background: </strong>Chronic subdural hematoma (CSDH) is a prevalent neurosurgical condition with high recurrence rates after standard surgical evacuation. Middle meningeal artery embolization (MMAE) has emerged as a potential adjunct to reduce recurrence by targeting the vascular supply of neomembranes.</p><p><strong>Objective: </strong>To evaluate the efficacy and safety of MMAE combined with surgery versus standalone surgical evacuation in patients with CSDH, through a comprehensive systematic review and meta-analysis, including separate analysis of randomized controlled trials (RCTs).</p><p><strong>Methods: </strong>A systematic search of PubMed, Scopus, Web of Science, Embase, and Google Scholar was performed through March 2025. Dual-arm studies comparing MMAE plus surgery with surgery alone were included. Outcomes of interest were recurrence, complications, all-cause mortality, and functional outcome (modified Rankin Scale ≤ 2; mRS ≤ 2). Pooled risk ratios (RRs) with 95% confidence intervals (CIs) were estimated using a random-effects model. Bias and evidence certainty were assessed via RoB tools and GRADE.</p><p><strong>Results: </strong>Twenty-five studies (6 RCTs, 19 observational) comprising 119,812 patients were included. MMAE plus surgery significantly reduced recurrence (RR = 0.47, 95% CI: 0.36-0.62, p < 0.001; I² = 3.0%), without increasing complications (RR = 1.02, 95% CI: 0.8-1.3) or mortality (RR = 0.98, 95% CI: 0.72-1.33) compared with surgery alone. Functional outcomes were similar between both approaches (RR = 1.07, 95% CI: 0.93-1.23). Subanalysis of RCTs, was consistent with overall analysis showing a significant reduction in recurrence (RR = 0.44, 95% CI: 0.25-0.78) with MMAE plus surgery, without an increase in complications or mortality compared to surgery alone.</p><p><strong>Conclusion: </strong>MMAE as an adjunct to surgery significantly lowers recurrence in CSDH. No significant differences in complications, mortality, or functional outcomes were detected compared with surgery alone; however, these outcomes are less common, and available studies may not have been adequately powered to exclude small but clinically meaningful effects.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145302288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective detection of missed intra-cranial aneurysms on computed tomography angiography using a commercial deep learning algorithm.","authors":"Tamer Sobeh, Shai Shrot, Mati Bakon, Gal Yaniv, David Orion, Eli Konen, Chen Hoffmann","doi":"10.1007/s00234-025-03810-y","DOIUrl":"https://doi.org/10.1007/s00234-025-03810-y","url":null,"abstract":"<p><strong>Background: </strong>The early identification of intracranial aneurysms (IAs) enables risk stratification and the timely initiation of optimal management. This study aimed to identify patients with missed aneurysms for follow-up and possible treatment, and to evaluate the effectiveness of a commercial deep learning algorithm in retrospectively detecting missed IAs on CTA.</p><p><strong>Methods: </strong>All consecutive head CTA studies of adult patients performed at a single referral center between February 18, 2020, and July 31, 2022, were retrospectively collected. A machine learning algorithm using natural language processing (NLP) classified radiology reports as positive or negative for aneurysms, and a convolutional neural network (CNN) algorithm analyzed the imaging data. Concordant results with the original reports were accepted as ground truth, while discordant cases were reviewed by three neuroradiologists, with majority voting determining the reference standard.</p><p><strong>Results: </strong>A total of 2,615 head CTA studies were analyzed. the algorithm flagged 34 suspected missed aneurysms, with 67% (23/34) confirmed as true positives by at least two neuroradiologists. This improved detection by 20.9% (23/110) or 0.88% of all studies. Most missed aneurysms were small (≤ 3 mm). There were 4 false negatives, resulting in a sensitivity of 96.36%, specificity of 99.56%, positive predictive value of 90.6%, and negative predictive value of 99.84%.</p><p><strong>Conclusion: </strong>This study highlights the potential of deep learning systems to detect missed intracranial aneurysms. Although the missed aneurysms in this cohort were predominantly small, follow-up or diagnostic digital subtraction angiography may still be warranted, depending on clinical characteristics and risk factors for aneurysm rupture.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145293059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning-based computed tomography reconstruction improves image quality but does not significantly affect Alberta stroke program early CT score evaluation in acute middle cerebral artery territory infarction.","authors":"Motoko Konno, Takahiro Otani, Masazumi Matsuda, Takuya Konno, Kento Hatakeyama, Aoi Otaka, Yusuke Takahashi, Hiroaki Shimizu, Naoko Mori","doi":"10.1007/s00234-025-03804-w","DOIUrl":"https://doi.org/10.1007/s00234-025-03804-w","url":null,"abstract":"","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145293066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}