Neuroradiology最新文献

{"title":"Spontaneous thrombosis of drainage vein in cavernoma-associated developmental venous anomaly.","authors":"Miguel Ossuna, Pedro Tadao Hamamoto Filho, Marco Antônio Zanini","doi":"10.1007/s00234-025-03775-y","DOIUrl":"https://doi.org/10.1007/s00234-025-03775-y","url":null,"abstract":"<p><p>A 57-year-old male with multiple supratentorial and infratentorial cavernomas presented with subacute-onset headache, tinnitus, and worsening neurological deficits. Imaging revealed spontaneous thrombosis of a previously documented developmental venous anomaly (DVA) in the posterior fossa, resulting in cerebellar parenchymal hemorrhage and posterior fossa hypertension consistent with venous infarction. This case highlights the rare occurrence of spontaneous DVA thrombosis, emphasizing its potential for severe complications, such as venous ischemic infarction, parenchymal hemorrhage, venous congestion, or subarachnoid hemorrhage, as well as the importance of sequential imaging in documenting pathological progression.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145252078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-related changes in cerebral blood flow and arterial transit time in children: insights from single- and multi-delay ASL.","authors":"Yeva Prysiazhniuk, Rui Duarte Armindo, Sasha Alexander, Michael Moseley, Kristen W Yeom, Jakub Otáhal, Martin Kynčl, Elizabeth Tong, Jan Petr, Moss Y Zhao, Gary K Steinberg","doi":"10.1007/s00234-025-03794-9","DOIUrl":"https://doi.org/10.1007/s00234-025-03794-9","url":null,"abstract":"<p><strong>Background: </strong>Arterial spin labeling (ASL) MRI is a non-invasive perfusion imaging technique with potential for assessing hemodynamics in children. However, understanding hemodynamic changes in developing brains remains challenging. This study investigates the impact of normal brain development on ASL-derived cerebral blood flow (CBF) and arterial transit time (ATT) in MR-negative children.</p><p><strong>Methods: </strong>Thirty-two pediatric subjects (ages 0.7-17.9 years, mean 9.3 ± 5.3y, 19 male) with MR-negative findings were retrospectively included. Four pseudo-continuous ASL (PCASL) scans were acquired: single-delay (PLD 1525 or 2025 ms) and multi-delay (3 or 7 delays). CBF and ATT in supratentorial gray matter (GM), white matter (WM), and total-brain (TB) regions were analyzed using paired t-tests, Cohen's d, Spearman correlation, and mixed linear regression models.</p><p><strong>Results: </strong>Single-delay CBF was significantly higher than 3-delay CBF in GM and WM (p < 0.001 PLD 2025 ms; p = 0.02 PLD 1525 ms). WM and TB CBF correlated negatively with age (rho=-0.56, p < 0.001), whereas GM CBF showed no significant correlation (rho=-0.03, p = 0.87); the trends differed significantly (p = 0.01). GM and TB ATT increased with age (r² > 0.11, p < 0.021). WM and TB CBF correlated with WM and combined WM/GM volumes (rho=-0.42, p = 0.02; rho=-0.46, p = 0.008).</p><p><strong>Conclusion: </strong>GM and WM exhibit distinct age-related hemodynamic patterns. WM perfusion declines with age and correlates with WM volume, while GM perfusion remains stable. The progressive increase in GM ATT highlights the need for cautious interpretation of single-delay ASL data in pediatric studies.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145239135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LVIS versus enterprise stents for stent-assisted coiling of intracranial aneurysms: a systematic review and meta-analysis.","authors":"Lucca Tamara Alves Carretta, Ocilio Ribeiro Gonçalves, Mariana Lee Han, Kenzo Ogasawara Donato, Yasmin Picanço Silva, Luciano Falcão, Rian Barreto Arrais Rodrigues de Morais, Nicole Baptista de Oliveira, Mariana Letícia de Bastos Maximiano, Ahmet Günkan","doi":"10.1007/s00234-025-03748-1","DOIUrl":"https://doi.org/10.1007/s00234-025-03748-1","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review and meta-analysis aimed to compare the clinical and angiographic outcomes of the LVIS versus the Enterprise stent for the treatment of intracranial aneurysms (IAs).</p><p><strong>Methods: </strong>Eligible studies were extracted from PubMed, Scopus, and Embase comparing LVIS/Enterprise. Data on angiographic occlusion rates, neurological deficits, in-stent stenosis, hemorrhagic complications, thromboembolic complications and aneurysm recanalization were analyzed with statistical methods.</p><p><strong>Results: </strong>5 observational studies (912 patients: 457 treated with LVIS and 455 with Enterprise) were analyzed. LVIS was linked to a significantly lower likelihood of Raymond-Roy Occlusion Classification (RROC) Class 3 (RR 0.30; 95% CI 0.13-0.71; I²=0%) and aneurysm recanalization (RR 0.38; 95% CI 0.18-0.82; I²=0%). No statistically significant differences were found between the two groups regarding mRS 0-2, RROC Class 1 or 2, or the incidence of neurological deficits, in-stent stenosis, hemorrhagic or thromboembolic events.</p><p><strong>Conclusion: </strong>LVIS and Enterprise demonstrate safety and efficacy in the endovascular management of IAs. LVIS may provide improved angiographic outcomes by lowering the risk of recurrence and incomplete occlusion. These findings support its potential advantage in treating complex aneurysms. Further confirmation through randomized controlled trials (RCT) is needed.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"White matter and glymphatic system alterations in patients with focal epilepsy: insights from PSMD and DTI-ALPS index.","authors":"Ho-Joon Lee, Dong Ah Lee, Kang Min Park","doi":"10.1007/s00234-025-03782-z","DOIUrl":"https://doi.org/10.1007/s00234-025-03782-z","url":null,"abstract":"<p><strong>Objectives: </strong>Peak width of skeletonized mean diffusivity (PSMD) is a neuroimaging biomarker of white matter integrity in cerebral small-vessel disease. However, the significance of PSMD in focal epilepsy remains unclear. This study aimed to investigate alterations in white matter microstructure and glymphatic system function in patients with focal epilepsy by comparing PSMD and the diffusion tensor imaging (DTI) along perivascular spaces (DTI-ALPS) index with healthy controls and by exploring their associations with seizure lateralization and treatment response.</p><p><strong>Methods: </strong>We retrospectively analyzed DTI data from 102 patients with focal epilepsy and 88 healthy controls. PSMD values and the DTI-ALPS index were obtained using a standard processing pipeline, and between-group comparisons were performed. Associations between PSMD and clinical characteristics were also evaluated.</p><p><strong>Results: </strong>PSMD was significantly higher in patients with focal epilepsy than in healthy controls (2.218 ± 0.355 × 10^-4 vs. 2.051 ± 0.176 × 10^-4 mm²/s, p < 0.001). In addition, PSMD was significantly higher in the ipsilateral hemisphere than in the contralateral hemisphere (2.239 ± 0.356 × 10^-4 vs. 2.109 ± 0.325 × 10^-4 mm²/s, p = 0.005). The DTI-ALPS index was significantly lower in patients with focal epilepsy than in healthy controls (1.628 ± 0.256 vs. 1.718 ± 0.305, p = 0.028). PSMD was positively correlated with age in patients (r = 0.417, p < 0.001) and controls (r = 0.343, p = 0.001) and negatively correlated with the DTI-ALPS index in patients (r=-0.376, p < 0.001) and controls (r=-0.409, p < 0.001).</p><p><strong>Conclusion: </strong>Our findings suggest that PSMD is increased in patients with focal epilepsy, potentially reflecting microstructural white matter alterations. Increased PSMD in the ipsilateral hemisphere supports its potential role in lateralizing seizure onset. The significant positive correlation between PSMD and age and the inverse relationship between PSMD and the DTI-ALPS index suggest that PSMD is associated with changes in the glymphatic system and white matter microstructure.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Technical effectiveness and safety of emergent stenting in patients with acute ischemic stroke and carotid near-occlusion.","authors":"Andrés García Pastor, Isabel Lera Ramírez, Alejandro Bonilla Tena, David Seoane, Patricia Calleja, Fernando Ostos, Elena De Celis-Ruiz, Carlos Gómez Escalonilla, Patricia Simal, Alfonso López-Frías López-Jurado, Daniel Perez Gil, Rocío Vera Lechuga, Cristina Moreno-López, Jose Carlos Fernandez-Ferro, María Teresa Montalvo Moraleda, Javier Roa Escobar, Araceli García Torres, Inmaculada Navas Vinagre, Eduardo Escolar Escamilla, Rodrigo Terrero Carpio, Guillermo Martín Ávila, Ana María Iglesias Mohedano, Marta Vales Montero, Antonio Gil Núñez","doi":"10.1007/s00234-025-03784-x","DOIUrl":"https://doi.org/10.1007/s00234-025-03784-x","url":null,"abstract":"<p><strong>Background: </strong>The increased very early risk (within the first 2 days after presenting event) of recurrent stroke among patients with symptomatic carotid near-occlusion (SCNO) and full collapse (FC) might justify ultra-early carotid revascularization of these patients. However, we lack data about technical effectiveness and safety of this approach in SCNO. This study aims to assess the feasibility and safety of emergent carotid stenting (eCAS) in patients with SCNO.</p><p><strong>Methods: </strong>Multicenter study including patients with acute stroke and extracranial carotid stenosis or occlusion undergoing mechanical thrombectomy and eCAS. The main outcomes were revascularization failure (incomplete carotid revascularization/occlusion at 48h), intracerebral hemorrhage (ICH) and symptomatic ICH (sICH). Patients with SCNO with and without FC were compared with the remaining patients.</p><p><strong>Results: </strong>309 patients were included, 215 (69.6%) males, mean age (SD) 67.2 (12.8). 45 patients had SCNO and 16 SCNO + FC. Revascularization failure occurred in 15.6% of SCNO and in 13.4% of the remaining patients (p = 0.826), with no differences between SCNO with or without FC. ICH was more common in patients with SCNO (42% for all SCNO, 47% for SCNO + FC, and 24% for the remaining patients; p = 0.027). This increased risk of ICH associated with SCNO persisted in the multivariate analysis (OR 3.49 [95%CI 1.63 - 7.48], p = 0.001). No significant differences in the rate of sICH were observed between SCNO and the remaining patients.</p><p><strong>Conclusions: </strong>The use of eCAS in acute SCNO seems to be feasible. However, the safety of the procedure is uncertain, as it could be associated with an increased risk of ICH.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145200459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative digital subtraction angiography analysis and predictive factors for incomplete occlusion in posterior communicating artery aneurysms after endovascular treatment.","authors":"Sheng-Qi Hu, Chun Zeng, Jinbiao Yao, Mirzat Turhon, Ting Liu, Wenqiang Li, Xinjian Yang","doi":"10.1007/s00234-025-03780-1","DOIUrl":"https://doi.org/10.1007/s00234-025-03780-1","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to identify predictive factors for incomplete occlusion in posterior communicating artery (PCoA) aneurysms after endovascular treatment (EVT) and investigate the role of fetal-type posterior cerebral artery (fPCA) in occlusion outcomes using quantitative digital subtraction angiography (QDSA).</p><p><strong>Methods: </strong>We analyzed 287 patients with 292 PCoA aneurysms treated with EVT between 2016 and 2022. Aneurysms were categorized into incomplete (n = 49) and complete (n = 243) occlusion groups based on follow-up DSA. Clinical, morphological, and hemodynamic parameters from QDSA were compared, and independent risk factors were identified via multivariate logistic regression. Predictive performance was evaluated using area under the curve (AUC) and subgroup analysis with Benjamini-Hochberg correction for fPCA effects.</p><p><strong>Results: </strong>Independent risk factors for incomplete occlusion included size (p < 0.001, OR = 1.127), neck cerebral blood flow (CBF) (p = 0.001, OR = 4.024), simple coiling (p < 0.001, OR = 4.635), ruptured status (p = 0.002, OR = 3.281), and fPCA (p = 0.030, OR = 2.218). AUCs for the combined model, size, neck CBF, simple coiling, ruptured status, and fPCA were 0.822, 0.721, 0.708, 0.656, and 0.603, respectively. In the fPCA subgroup, ruptured status, neck CBF, neck cerebral blood volume (CBV), PCoA CBF, and PCoA CBV showed significance, while in the non-fPCA subgroup, only simple coiling and size remained significant.</p><p><strong>Conclusion: </strong>Size, neck CBF, simple coiling, ruptured status, and fPCA are independent risk factors for incomplete occlusion in PCoA aneurysms treated with EVT. fPCA likely influences incomplete occlusion through hemodynamic changes.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structured assessment of brain MRI in Covid-19-related neurological disease: an international multicentre study.","authors":"Stéphane Kremer, Tarek A Yousry, Rafael Rehwald, François Lersy, Nicolas Meyer, Simonetta Gerevini, Angela Napolitano, Àlex Rovira, Ng Karelys, Leandro Tavares Lucato, Maria da Graça Morais Martin, Ana Lícia da Rocha Alves Pinto, Luke Dixon, Brynmor Jones, Ana Ramos, Elena Salvador, Núria Bargalló, Laura Oleaga, Nicoletta Anzalone, Andrea Falini, Francesco Carletti, Chandrasekhar Hoskote, Agathe Chammas, Benoit Lhermitte, Béatrice Lannes, Thibaut de Misouard, François Cotton, Hans Rolf Jäger","doi":"10.1007/s00234-025-03787-8","DOIUrl":"https://doi.org/10.1007/s00234-025-03787-8","url":null,"abstract":"<p><strong>Purpose: </strong>Neuroradiological findings associated with neurological presentations in acute SARS-CoV-2 infection are very heterogeneous. We aimed to develop a standardized framework for describing MR neuroimaging patterns in Covid-19, to test this in an international multicentre study and to determine the prevalence of observed MRI patterns and their association with clinical presentation and outcome.</p><p><strong>Methods: </strong>An international expert consortium developed a framework for assessment of brain MRI patterns in Covid-19 based on published literature and professional experience. We performed a retrospective analysis of the proposed framework, involving brain MRI scans from 458 Covid-19 patients with neurological symptoms, including data from 1 February to 31 May 2020. Two readers at 25 centres across five countries assessed the local MRI studies regarding the presence of one or more predefined MRI patterns. Imaging and clinical data were analysed using Bayesian statistics.</p><p><strong>Results: </strong>Of 458 patients, 58.5% had an abnormal MRI. Overall, 94% of all imaging pathologies seen were captured by our proposed classification. Ischemic strokes were the most frequent pattern overall (25.6%), followed by microhaemorrhages (15.9%). Ischemic infarct patterns were more frequent in non-ICU patients, while the haemorrhagic patterns were more frequent in ICU patients. White matter lesions (10.9%) were more frequent than grey matter lesions (8.1%), and leptomeningeal contrast enhancement was present in 8.3% of patients. Patient outcome was not associated with any MRI patterns.</p><p><strong>Conclusion: </strong>Our proposed classification of specific MRI patterns in Covid-19, covered 94% of observed abnormalities, while patient outcome, death or home discharge, was not associated with any MRI patterns.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between cerebrovascular imaging markers and glymphatic function in a large-scale cognitively normal population.","authors":"Ji Su Ko, Yangsean Choi, Eunseon Jeong, Ji Eun Park, Ho Sung Kim","doi":"10.1007/s00234-025-03786-9","DOIUrl":"10.1007/s00234-025-03786-9","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the association between cerebrovascular imaging markers and glymphatic function in cognitively normal individuals.</p><p><strong>Methods: </strong>This retrospective study included 574 cognitively normal participants who underwent brain magnetic resonance imaging from January to October 2023. Glymphatic function was assessed using diffusion tensor image analysis along the perivascular space index (ALPS-index). Cerebrovascular imaging markers, including white matter hyperintensity (WMH) burden, cerebral microbleeds (CMBs), and choroid plexus volume (CPV), were quantified using automated segmentation methods. The presence of lacunes in the basal ganglia or old infarcts in other areas was visually determined. Associations between cerebrovascular markers and ALPS-index were analyzed using multivariable regression and partial correlation analyses.</p><p><strong>Results: </strong>The mean age of the included participants was 68.9 ± 10.4 years (male, 40.9%; hypertension, 43.7%; diabetes, 20.4%; Mini-Mental State Examination [MMSE] score, 27.6 ± 1.6). A lower ALPS-index, reflecting impaired glymphatic clearance, was significantly associated with higher WMH burden (β=-0.231, p < 0.001), increased CPV fraction (β=-0.234, p < 0.001), and a greater number of deep CMBs (β=-0.087, p = 0.038). The participants with basal ganglia lacunes (ALPS-index: 1.32 ± 0.19), old infarcts other than basal ganglia (ALPS-index: 1.34 ± 0.19), or both (ALPS-index: 1.27 ± 0.19) had significantly lower ALPS-indices than those without these conditions (ALPS-index: 1.43 ± 0.21; all, p < 0.001).</p><p><strong>Conclusion: </strong>Cerebrovascular imaging findings are significantly associated with glymphatic dysfunction in cognitively normal individuals, highlighting the need for further studies on glymphatic-targeted interventions in cerebrovascular disease prevention.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regional T2 value differences assess lumbar disc degeneration: a 3.0-T MRI retrospective study.","authors":"Shunmin Wang, Jiangang Shi, Tiefeng Li, Xiaofeng Zhang, Kaiqiang Sun, Yu Chen","doi":"10.1007/s00234-025-03762-3","DOIUrl":"https://doi.org/10.1007/s00234-025-03762-3","url":null,"abstract":"<p><strong>Objectives: </strong>To quantify region-specific T2 relaxation dynamics in lumbar disc degeneration and evaluate their correlations with Pfirrmann grades and herniation morphology, focusing on early microstructural detection.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed 130 lumbar discs (L1-S1) from 26 patients with single-segment disc herniation using 3.0-T MRI. T2 relaxation mapping was systematically performed with anatomical compartment segmentation defining four regions of interest: anterior annulus fibrosus, nucleus pulposus, posterior annulus fibrosus, and herniated tissue. Standardized circular ROIs (2.5-mm diameter) were applied to non-herniated regions, while herniations underwent area-matched elliptical contouring. Pfirrmann grading (I-V) was independently validated by two board-certified musculoskeletal radiologists. Statistical analyses employed nonparametric Kruskal-Wallis tests for inter-grade T2 comparisons and Spearman's rank correlation (ρ) to quantify degeneration associations.</p><p><strong>Results: </strong>Statistically significant differences in T2 values were observed across the three anatomical compartments (*p*<0.05). T2 relaxation times demonstrated an inverse correlation with Pfirrmann degeneration grades, exhibiting the strongest association in the nucleus pulposus (middle compartment; r=-0.542). This correlation intensified with advancing degeneration. Sagittal T2 comparisons revealed significant differences between Pfirrmann grade I/II and IV/V groups in all compartments, while the nucleus pulposus showed significant differences between grades I/II and III. Within identical degeneration grades, nucleus pulposus T2 values exceeded those of the anterior annulus fibrosus. Specifically, in Pfirrmann I/II discs, posterior annulus values surpassed anterior annulus values, whereas in grade IV/V discs, nucleus pulposus values exceeded posterior annulus values, with no significant anterior-posterior difference. Cross-sectionally, the nucleus pulposus exhibited the highest T2 values, while herniated tissue demonstrated the lowest.</p><p><strong>Conclusions: </strong>Region-specific T2 mapping demonstrates potential for detecting early microstructural degeneration within lumbar intervertebral discs.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"European Society of Neuroradiology (ESNR).","authors":"","doi":"10.1007/s00234-025-03765-0","DOIUrl":"10.1007/s00234-025-03765-0","url":null,"abstract":"","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}