Neuroradiology最新文献

{"title":"White matter injuries mediate brain age effects on cognitive function in cerebral small vessel disease.","authors":"Yuanhao Li, Tian Tian, Yuanyuan Qin, Shun Zhang, Chengxia Liu, Wenzhen Zhu","doi":"10.1007/s00234-025-03568-3","DOIUrl":"https://doi.org/10.1007/s00234-025-03568-3","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to investigate the potential effect of compromised structural integrity on cerebral aging and cognitive function in cerebral small vessel disease (CSVD).</p><p><strong>Methods: </strong>Fifty-five CSVD patients and 42 controls underwent three-dimensional T1-weighted imaging and diffusion tensor imaging. Relative brain age (RBA) was computed to assess cerebral aging. Variables of structural integrity included cortical thickness, cortical volume, white matter hyperintensity (WMH) volume, peak width of skeletonized mean diffusivity (PSMD), ventricular volume, and choroid plexus volume. Mini-Mental State Examination (MMSE) was conducted to assess general cognition. Trail Making Test (TMT) and Auditory Verbal Learning Test were administered to evaluate executive function and episodic memory, respectively. Mediation analysis and multivariate linear regression with interaction terms were performed to explore the differential impacts of RBA on cognitive function and structural integrity between CSVD patients and controls.</p><p><strong>Results: </strong>RBA was significantly increased in CSVD patients compared to controls (p < 0.001). White matter injuries as assessed with PSMD (mediation magnitude: 41.1%) and WMH volume (mediation magnitude: 56.9%) significantly mediated the relationship between CSVD pathologies and RBA (p < 0.001). Higher RBA was significantly correlated with poorer scores of MMSE, TMT-A, and TMT-B in CSVD patients (p < 0.01). Additionally, PSMD (mediation magnitude: 57.8% in MMSE, 48.3% in TMT-A, and 28.8% in TMT-B) and WMH volume (mediation magnitude: 55.1% in MMSE) significantly mediated the relationship between RBA and cognitive function (p < 0.05).</p><p><strong>Conclusion: </strong>White matter injuries play a critical role in the cerebral aging and cognitive decline in CSVD patients.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The probability of cerebral amyloid angiopathy according to the Simplified Edinburgh CT criteria in a large, unselected lobar intracerebral hemorrhage population.","authors":"Amir Hillal, Trine Apostolaki-Hansson, Birgitta Ramgren, Björn Hansen, Bo Norrving, Johan Wassélius, Teresa Ullberg","doi":"10.1007/s00234-025-03555-8","DOIUrl":"https://doi.org/10.1007/s00234-025-03555-8","url":null,"abstract":"<p><strong>Purpose: </strong>Early identification of the underlying cause of intracerebral hemorrhage (ICH) is important for treatment and prognosis. This study aims to investigate the association of hematoma volume and other clinical parameters on the distribution of cerebral amyloid angiopathy (CAA) probability according to the simplified Edinburgh CT criteria in a large, unselected intracerebral hemorrhage (ICH) population.</p><p><strong>Method: </strong>Patients with spontaneous ICH residing in Skane county registered with clinical data in the Swedish Stroke Register 2016-2020 were included. Radiological parameters were evaluated using baseline non-contrast CT (NCCT) for categorization according to the simplified Edinburgh CT criteria by the presence of subarachnoid hemorrhage (SAH) and fingerlike-projections (FLP). Multivariable logistic regression analysis was used to determine factors associated with an increased (intermediate/high) CAA probability.</p><p><strong>Results: </strong>Of 666 patients with lobar ICH, 190 (29%) had high, 92 (14%) had intermediate, and 384 (58%) had low CAA probability. Patients with increased CAA probability presented more often with decreased level of consciousness, larger hematoma volumes, and higher 90-day mortality. Baseline hematoma volume [10-30 ml (OR = 4.03;95%CI: 2.26-7.19); 30-80 ml (OR = 12.00;95%CI:7.26-22.53); >80 ml (OR = 30.00;95%CI:15.94-59.09)], female sex (OR = 1.58;95%CI:1.08-2.32) and age (OR = 1.04;95%CI:1.02-1.06) were associated with an increased odds of having an increased CAA probability.</p><p><strong>Conclusion: </strong>We identified a strong association between baseline hematoma volume and an increased probability of CAA in lobar ICH patients on NCCT, indicating that large hematoma volumes alone may contribute to the occurrence of FLP and SAH, and act as a confounder for the simplified Edinburgh CT criteria. Validation against MRI is warranted.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concurrent brain structural and functional alterations related to cognition in patients with cerebral small vessel disease.","authors":"Wenwen Wang, Jing Huang, Runtian Cheng, Xiaoshuang Liu, Tianyou Luo","doi":"10.1007/s00234-025-03557-6","DOIUrl":"https://doi.org/10.1007/s00234-025-03557-6","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the concurrent brain structural and functional alterations related to cognition in patients with cerebral small vessel disease (CSVD).</p><p><strong>Methods: </strong>Thirty normal controls and 65 CSVD patients, including 33 patients with mild cognitive impairment and 32 patients with no cognitive impairment were included. Structural and resting-state functional MRI measures, including gray matter volume (GMV) and white matter volume (WMV) using voxel-based morphometry (VBM) analysis and amplitude of low-frequency fluctuation (ALFF), were obtained and compared among the three groups. Associations between cognitive scores and ALFF/VBM coupling in the co-altered regions were investigated in CSVD groups.</p><p><strong>Results: </strong>Multiple brain regions showed significant differences in GMV and WMV among the three groups (P < 0.01). Abnormal ALFF among the three groups was identified in the left putamen, Rolandic operculum, fusiform gyrus, caudate, parahippocampal gyrus, insula, middle cingulum, bilateral lingual gyrus, and right frontal lobe (P < 0.01). Importantly, a decrease in VBM and increase in ALFF in the left parahippocampal gyrus, caudate and Rolandic operculum, a reduction of the WMV and ALFF in the right superior frontal lobe, and a united rise of GMV and ALFF in the left caudate were detected in CSVD groups. In addition, abnormal ALFF/VBM coupling was significantly related to multiple cognitive assessments.</p><p><strong>Conclusion: </strong>The study indicated a reversed pattern of the brain structural deficits and functional activation in the left parahippocampal gyrus, caudate, and Rolandic operculum, suggesting structure-function decoupling in CSVD groups. These might help further understand the pathophysiological mechanism of CSVD.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"European Society of Neuroradiology (ESNR).","authors":"","doi":"10.1007/s00234-025-03559-4","DOIUrl":"10.1007/s00234-025-03559-4","url":null,"abstract":"","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduced DTI-ALPS index in tinnitus patients: DTI-ALPS as a mediator of sleep on tinnitus.","authors":"Yinfei Liang, Hui-Quan Wen, Ruo-Mi Guo, Gen-di Yin, Jian-Qi Zhao, Zhi-Cheng Li, Xiang-Li Zeng","doi":"10.1007/s00234-025-03556-7","DOIUrl":"https://doi.org/10.1007/s00234-025-03556-7","url":null,"abstract":"<p><strong>Background: </strong>Sleep disturbance is a common comorbidity in tinnitus patients, which may be attributed to changes in brain structure and function. The aim of this study was to explore the potential role of the glymphatic system (GS), a recently discovered pathway for brain waste clearance, in tinnitus and the associated sleep disturbance.</p><p><strong>Methods: </strong>The DTI-ALPS index of 22 tinnitus patients and 22 healthy controls (18-60 years old) were compared after controlling for age, sex, and handedness. Partial correlation and mediation analyses were performed to explore the association between the above parameters and clinical data.</p><p><strong>Results: </strong>Significant differences were found between the right-side DTI-ALPS index and the DTI-ALPS index of the healthy group. Furthermore, the DTI-ALPS index in tinnitus patients was significantly lower than that of the healthy group (1.288 vs. 1.422, p = 0.009). After adjusting for age and sex, the DTI-ALPS index correlated significantly with the Tinnitus Handicap Inventory (THI) scores (r = -0.587, p < 0.001). The DTI-ALPS index was negatively correlated with Pittsburgh Sleep Quality Index (PSQI) scores (r = -0.457, p = 0.032). The mediation analysis of the ALPS index, PSQI, and THI revealed a significant indirect effect of PSQI on the association between ALPS index and THI (p < 0.0001).</p><p><strong>Conclusion: </strong>The glymphatic system may influence sleep disturbance in tinnitus patients due to its role in brain waste clearance. We observed a decrease in DTI-ALPS in tinnitus patients, and our analyses suggest that sleep disturbances influence tinnitus through the mediation of DTI-ALPS. Thus, greater emphasis should be placed on averting sleep issues at Tinnitus.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating post-treatment residual intracranial arteriovenous shunting: a comparison of arterial spin labeling MRI and digital subtraction angiography.","authors":"Abraham Noorbakhsh, Mitchell T Wong, Divya S Bolar","doi":"10.1007/s00234-025-03548-7","DOIUrl":"https://doi.org/10.1007/s00234-025-03548-7","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy of arterial spin labeling (ASL) MRI in detecting residual arteriovenous (AV) shunting in treated arteriovenous malformations (AVMs) and fistulas (AVFs).</p><p><strong>Methods: </strong>A retrospective institutional review identified 29 patients with DSA-confirmed AV shunt lesions treated via embolization (n = 17), stereotactic radiosurgery (n = 2), surgical resection (n = 8), or combined embolization and surgical resection (n = 4), with corresponding baseline and post-treatment ASL and DSA studies. Two neuroradiologists independently assessed ASL images for residual AV shunting, with inter-rater agreement calculated. Disagreements were jointly reviewed to reach consensus. Sensitivity and specificity for using ASL to detect residual AV shunting were then determined using DSA as the gold standard reference.</p><p><strong>Results: </strong>Seventeen patients with Spetzler-Martin grades II-V AVMs were included: 76.5% with supratentorial nidus, and 52.9% with prior hemorrhage. Twelve AVF patients were included, including eight dural, one vein of Galen, two perimedullary, and one cavernous-carotid fistula. Inter-rater agreement for presence of residual AV shunting was strong (93.5%, κ = 0.87). Two disagreements involved AVM patients after surgical resection. Sensitivity and specificity of ASL for detecting residual was 94% and 93%, respectively. Within the AVM group, both metrics reached 100%, while for AVFs, they both decreased to 83%, with one false positive and one false negative.</p><p><strong>Conclusion: </strong>ASL MRI is highly sensitive and specific for detection of residual AV shunting across a wide spectrum of AV shunt pathologies and treatment modalities. ASL can play an important role as a non-invasive adjunct to DSA, potentially reducing the frequency of DSA during the continuum of post-treatment care.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated assessment of collateral circulation and infarct core: predictors of functional outcomes in acute ischemic stroke following endovascular thrombectomy.","authors":"Ingrid Požar, Fajko F Bajrović, Lan Umek, Katarina Šurlan Popović","doi":"10.1007/s00234-024-03519-4","DOIUrl":"https://doi.org/10.1007/s00234-024-03519-4","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the predictive value of automatically assessed collateral circulation (CC) and infarct core for functional outcome in acute ischemic stroke (AIS) patients treated with endovascular thrombectomy (EVT).</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of 208 patients with anterior large vessel occlusion treated with EVT. Two AI-powered software were used to automatically assess CC and infarct core. Comparative analyses included patient demographics, clinical and imaging data, and functional outcome. Univariate and multivariable logistic regression analyses were conducted to predict the 90-day functional outcome. A favorable outcome was defined as a modified Rankin scale (mRS) score ≤ 2.</p><p><strong>Results: </strong>Among the 208 patients, 114 (54.8%) were women and 94 were men, with a mean age of 71.4 ± 13.3 years. Patients with higher collateral score (CS) exhibited lower infarct core volumes (p < 0.001) and better mRS score at 90 days (p = 0.008). Among patients with a favorable outcome, the mean infarct core volume was lower compared to those with poor outcomes (5 mL vs. 8.6 mL, p = 0.003). In univariate logistic regression, both infarct core (OR 0.94, p = 0.005) and CS (OR 1.84, p = 0.014) were predictors of favorable outcome. However, in multivariable models, only infarct core remained a significant independent predictor [AORs of 0.95 (p = 0.021) and 0.96 (p = 0.039)].</p><p><strong>Conclusion: </strong>Automatically assessed infarct core is a robust predictor of functional outcome in AIS patients post-EVT, while CS's predictive value diminishes when adjusted for infarct core. These findings support the integration of AI-powered evaluations in clinical settings to improve prognosis and treatment strategies for AIS.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cortical structural degeneration and functional network connectivity changes in patients with subcortical vascular cognitive impairment.","authors":"Haixia Mao, Yachen Shi, Qianqian Gao, Min Xu, Xiaoyun Hu, Feng Wang, Xiangming Fang","doi":"10.1007/s00234-025-03550-z","DOIUrl":"https://doi.org/10.1007/s00234-025-03550-z","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the structural basis of functional network connectivity (FNC) changes and early cortical degenerative patterns in subcortical vascular cognitive impairment (SVCI).</p><p><strong>Methods: </strong>We prospectively included SVCI cases and healthy controls (HCs). FNC alterations were evaluated using group-independent component analysis of resting-state functional MRI data. Cortical microstructural and macrostructural alterations were assessed using gray matter-based spatial statistics analysis with neurite orientation dispersion and density imaging and cortical thickness analysis with FreeSurfer software on T1-weighted images, respectively. Spearman correlation analyses were performed to assess relationships between FNC alterations and cortical microstructural/macrostructural alterations and between FNC, cortical thickness, or neurite density index (NDI)/orientation dispersion index (ODI) alterations and cognitive performance.</p><p><strong>Results: </strong>Forty-six SVCI patients and 73 HCs were recruited. FNC analysis showed lower network connectivity between the visual network (VN) and sensorimotor network (SMN) in SVCI, positively correlated with information processing speed (p=0.008) and negatively with summary SVD score (p = 0.037). Cortical microstructural analyses exhibited a lower NDI, mainly in the VN and default mode network (DMN) areas (P_FWE < 0.05, cluster > 100 voxels), and lower ODI, mainly in the SMN and DMN areas (P_FWE < 0.05, cluster > 100 voxels) in SVCI, both of which were related to cognitive function (p < 0.05). However, cortical thickness did not differ between groups. Lower NDI in the lateral occipital cortex was linked to lower VN-SMN connectivity in SVCI (p = 0.002).</p><p><strong>Conclusion: </strong>Cortical microstructural alterations may serve as the basis for FNC changes in SVCI.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthetic MR: Clinical applications in neuroradiology.","authors":"Smily Sharma, Abhishek Nayak, Bejoy Thomas, Chandrasekharan Kesavadas","doi":"10.1007/s00234-025-03547-8","DOIUrl":"https://doi.org/10.1007/s00234-025-03547-8","url":null,"abstract":"<p><strong>Purpose: </strong>Synthetic MR is a quantitative MRI method that measures tissue relaxation times and generates multiple contrast-weighted images using suitable algorithms. The present article principally discusses the multiple dynamic multiple echo (MDME) technique of synthetic MR and briefly describes other quantitative MR sequences.</p><p><strong>Methods: </strong>Using illustrative cases, various applications of the MDME sequence in neuroradiology are explained. The MDME sequence allows rapid quantification of tissue relaxation times in a scan duration of 5-7 minutes for full brain coverage. It also has the additional advantages of myelin quantification and automatic segmentation of brain volumes.</p><p><strong>Results: </strong>Applications including reducing scan time, improved detection of demyelinating plaques in Multiple Sclerosis (MS), objective assessment and follow-up for brain atrophy in neurodegenerative MS and dementia cases, and applications in stroke imaging and neuro-oncology are discussed. Uses in the pediatric population, including assessment of brain development and progression of myelination in children, evaluation of white matter disorders, and evaluation of pediatric and adult epilepsy, are elaborated. Quantitative evaluation by synthetic MR is discussed, which allows homogenization and objectification of the radiology data and can serve as a valuable source for artificial intelligence and future multicentre studies. A brief discussion on the technique, other quantitative MR methods, and limitations of the MDME sequence is also presented.</p><p><strong>Conclusion: </strong>The article intends to provide an explicit and comprehensive review of the applications of synthetic MR in neuroradiology, exploring its potential as a routine sequence in daily neuroimaging practice.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143067014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep orbital puncture of the superior ophthalmic vein for embolization of indirect carotid-cavernous fistula: a case report, technical note and review of the current literature.","authors":"Luís Gustavo Biondi Soares, Filipi Fim Andreão, Felipe Salvagni Pereira, Dmitriy Sergeyevich Korotkov, Luis F Fabrini Paleare, Leonardo Rocha-Carneiro García-Zapata, Leandro Assis Barbosa","doi":"10.1007/s00234-025-03545-w","DOIUrl":"https://doi.org/10.1007/s00234-025-03545-w","url":null,"abstract":"<p><strong>Purpose: </strong>Carotid-cavernous fistulas (CCFs) are abnormal connections between the carotid artery and cavernous sinus, often causing ocular symptoms like chemosis, proptosis, and diplopia. Endovascular embolization is the preferred treatment, typically performed via the transfemoral transvenous route through the inferior petrosal sinus (IPS). However, we present a case and a systematic review of indirect CCF treated through deep orbital puncture of the superior ophthalmic vein (SOV) for embolization.</p><p><strong>Methods: </strong>We systematically revised the current literature on PubMed, Web of Science, and Embase, based on PRISMA guideline, concerning the deep orbital puncture of the SOV for embolization of indirect CCFs.</p><p><strong>Results: </strong>Our systematic review identified only eight eligible studies encompassing 17 patients, ranging in age from 34 to 82 years, underscoring the rarity of this specific approach. The most frequently used trajectory directed the needle along the floor of the orbit towards the superior orbital fissure or orbital apex, and a variety of embolization materials were used in the studies. While the technique has been mentioned in the literature, our analysis indicates that it remains infrequently reported, with many cases lacking consistent procedural details. Furthermore, we present a case of a 63-year-old woman with imaging suggesting a CCF and compatible symptoms. A transorbital puncture of the SOV was performed. Embolization was successfully achieved with ethylene vinyl alcohol copolymer. The follow-up confirmed the resolution of the CCF without new neurological deficits and no new symptoms.</p><p><strong>Conclusion: </strong>This case highlights transorbital SOV puncture as a feasible and minimally invasive alternative for treating CCFs when conventional access is unsuccessful.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143040079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}