Neuroradiology最新文献

{"title":"Dose-response and infusion duration of intra-arterial nimodipine in cerebral vasospasm after aneurysmal subarachnoid hemorrhage: a single-center case series.","authors":"Adrien Guenego, Hamza Adel Salim, Fabio Silvio Taccone, Jeremy J Heit, Maud Wang, Niloufar Sadeghi, Noémie Ligot, Valentina Lolli, Vivek Yedavalli, Max Wintermark, Fadi Tannouri, Boris Lubicz","doi":"10.1007/s00234-025-03699-7","DOIUrl":"10.1007/s00234-025-03699-7","url":null,"abstract":"<p><strong>Background: </strong>This single-center case series evaluates the effects on arterial diameter, perfusion imaging, and safety of intra-arterial (IA) nimodipine administration for CV following aSAH.</p><p><strong>Methods: </strong>In this prospective single-center observational study (SAVEBRAIN PWI; NCT05276934), 14 patients with CV refractory to medical treatment were treated with IA nimodipine. We assessed changes in vessel diameter and perfusion parameters pre- and post-treatment. Associations between nimodipine dose, infusion duration, and outcomes were analyzed using regression models.</p><p><strong>Results: </strong>The median age of patients was 48 years; 50% were male. The median nimodipine dose was 2.00 mg with a median infusion duration of 10 minutes. Post-treatment, the median artery diameter increased from 1.50 mm to 1.90 mm (25% change), TMAX decreased from 2.58 to 2.11 seconds, and TTD decreased from 4.58 to 4.09 seconds. Higher nimodipine doses (> 2 mg) were associated with increased odds of hypotension requiring injection breaks (OR 3.6, 95% CI 2.1 to 5.6, p < 0.001). Retreatment was necessary in 69% of cases, with a median time to retreatment of 2 days.</p><p><strong>Conclusions: </strong>IA nimodipine administration appears to improve vascular diameters and perfusion parameters in CV following aSAH but carries a significant risk of hypotension, especially at doses > 2 mg. Longer infusion durations may reduce hypotension risk. These findings emphasize the need for careful dose management and further research to standardize treatment protocols.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2187-2197"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Boosting LLM-assisted diagnosis: 10-minute LLM tutorial elevates radiology residents' performance in brain MRI interpretation.","authors":"Su Hwan Kim, Severin Schramm, Jonas Wihl, Philipp Raffler, Marlene Tahedl, Julian Canisius, Ina Luiken, Lukas Endrös, Stefan Reischl, Alexander Marka, Robert Walter, Mathias Schillmaier, Claus Zimmer, Benedikt Wiestler, Dennis Martin Hedderich","doi":"10.1007/s00234-025-03664-4","DOIUrl":"10.1007/s00234-025-03664-4","url":null,"abstract":"","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2069-2081"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review on learning-based algorithms for tractography and human brain white matter tracts recognition.","authors":"Amin Barati Shoorche, Parastoo Farnia, Bahador Makkiabadi, Alexander Leemans","doi":"10.1007/s00234-025-03637-7","DOIUrl":"10.1007/s00234-025-03637-7","url":null,"abstract":"<p><strong>Purpose: </strong>Human brain fiber tractography using diffusion magnetic resonance imaging is a crucial stage in mapping brain white matter structures, pre-surgical planning, and extracting connectivity patterns. Accurate and reliable tractography, by providing detailed geometric information about the position of neural pathways, minimizes the risk of damage during neurosurgical procedures.</p><p><strong>Methods: </strong>Both tractography itself and its post-processing steps such as bundle segmentation are usually used in these contexts. Many approaches have been put forward in the past decades and recently, multiple data-driven tractography algorithms and automatic segmentation pipelines have been proposed to address the limitations of traditional methods.</p><p><strong>Results: </strong>Several of these recent methods are based on learning algorithms that have demonstrated promising results. In this study, in addition to introducing diffusion MRI datasets, we review learning-based algorithms such as conventional machine learning, deep learning, reinforcement learning and dictionary learning methods that have been used for white matter tract, nerve and pathway recognition as well as whole brain streamlines or whole brain tractogram creation.</p><p><strong>Conclusion: </strong>The contribution is to discuss both tractography and tract recognition methods, in addition to extending previous related reviews with most recent methods, covering architectures as well as network details, assess the efficiency of learning-based methods through a comprehensive comparison in this field, and finally demonstrate the important role of learning-based methods in tractography.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2041-2067"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Puncture artery steno-occlusion after transradial and transulnar neurointervention: incidence, predictors, and follow-up outcomes.","authors":"Keisuke Yoshida, Kazuma Kowata, Takayuki Yatsu, Naoko Shibusawa, Natsumi Sato, Rikako Mogi, Kazunori Akaji","doi":"10.1007/s00234-025-03703-0","DOIUrl":"10.1007/s00234-025-03703-0","url":null,"abstract":"<p><strong>Purpose: </strong>The transradial approach is increasingly used in neurointervention due to its minimally invasive nature and lower risk of severe access-related complications. However, radial artery steno-occlusion, although generally asymptomatic, may limit future vascular access. This study aimed to evaluate the incidence, predictors, and recanalization of puncture artery steno-occlusion following trans-wrist neurointervention.</p><p><strong>Methods: </strong>A retrospective institutional review was conducted on transradial and transulnar neurointerventions performed between February 2022 and May 2024. Postprocedural ultrasound was performed on the following day to assess puncture artery stenosis or occlusion. Risk factors were evaluated using univariate and multivariate logistic regression analyses. Follow-up ultrasound was conducted when available to assess recanalization.</p><p><strong>Results: </strong>Among 96 therapeutic trans-wrist procedures, puncture artery steno-occlusion was observed in 21 cases (22%). Complete occlusion occurred in 16 cases (17%), all asymptomatic. Multivariate analysis identified local anesthesia (OR 8.0, p < 0.05) and absence of preprocedural antiplatelet medication (OR 4.3, p < 0.05) as significant risk factors. The steno-occlusion rate was lower (6.6%) in cases performed under general anesthesia with preprocedural antiplatelet therapy. Follow-up ultrasound (median: 3.5 months) was available in 11 cases (52%), revealing persistent stenosis in all 4 stenosis cases and spontaneous recanalization in 4 of 7 occlusion cases (57%).</p><p><strong>Conclusion: </strong>Puncture artery steno-occlusion occurred in 22% of therapeutic trans-wrist neurointerventions. Local anesthesia and absence of preprocedural antiplatelet medication were significant risk factors. Follow-up revealed both persistent steno-occlusion and recanalization, underscoring the importance of vascular reassessment before repeated access.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2179-2185"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of cerebral cavernous malformation associated developmental venous anomalies in gradient-echo and susceptibility-weighted magnetic resonance imaging: can we skip the contrast?","authors":"Laurèl Rauschenbach, Alejandro N Santos, Jan Rodemerk, Hanah H Gull, Thiemo F Dinger, Adrian Engel, Maximilian Schüssler, Yan Li, Marvin Darkwah Oppong, Ramazan Jabbarli, Benedikt Frank, Michael Forsting, Karsten H Wrede, Ulrich Sure, Philipp Dammann","doi":"10.1007/s00234-025-03666-2","DOIUrl":"10.1007/s00234-025-03666-2","url":null,"abstract":"<p><strong>Purpose: </strong>Hemosiderin-sensitive MRI sequences are commonly utilized for microbleed identification in cerebral cavernous malformations (CCM). Efficacy of susceptibility-weighted (SWI) and gradient-echo T2*-weighted imaging (GRE-T2*) sequences in detecting CCM-associated developmental venous anomalies (DVA) remains uncertain.</p><p><strong>Methods: </strong>We conducted a retrospective review of our institutional CCM database. Inclusion criteria comprised baseline characteristics and MRI datasets involving contrast-enhanced T1 (CE-T1), T2, and SWI or GRE-T2* sequences. The presence of CCM-related DVA was determined utilizing CE-T1 imaging. A subgroup of 200 patients, evenly distributed with or without DVA, underwent random selection for analysis, with 50 patients each having SWI and GRE-T2* imaging. The presence of DVA was evaluated by two blinded neuroradiologists based on SWI or GRE-T2* sequences. Interrater agreement, sensitivity, and specificity values for SWI and GRE-T2* sequences were analyzed.</p><p><strong>Results: </strong>Imaging assessment demonstrated observer agreement in 76% of the SWI sequences (K = 0.51, p <0.001) and 82% of the GRE-T2* images (K = 0.39, p <0.001). While SWI sequences exhibited a sensitivity of 81.4% and a specificity of 60.6%, GRE-T2* sequences showed a sensitivity of 19.1% and a specificity of 97.5%. Misdiagnoses were frequent in small vessel DVAs, whereas large vessel DVAs were associated with higher diagnostic accuracy in both SWI and GRE-T2* sequences (p =0.002).</p><p><strong>Conclusion: </strong>Evaluation of SWI and GRE-T2* sequences for assessing CCM-related DVA appears less effective than the routine use of CE-T1 sequences. The use of contrast agents still appears necessary for detailed diagnostics and appropriate surgery planning.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2005-2013"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144285749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early venous filling following reperfusion therapy in acute ischemic stroke: a systematic review and meta-analysis.","authors":"Natan Lucca Lima, Marcos Henrique da Silva Mezzari, Luís Cláudio Izidio Costa Júnior, Davi Orli Machado Grüdtner, Bárbara Ghizoni Maggi, Darlos Kelvin de Azevedo, João Cândido Spezia de Souza, Wilson Jordão Mota Bezerra Júnior, Yasmin Guimarães Rodrigues, Gustavo Rassier Isolan","doi":"10.1007/s00234-025-03722-x","DOIUrl":"https://doi.org/10.1007/s00234-025-03722-x","url":null,"abstract":"<p><strong>Background: </strong>Early venous filling (EVF), detected by digital subtraction angiography after endovascular therapy, may indicate hyperperfusion and vascular injury. Emerging evidence suggests that EVF is associated with adverse outcomes and complications, highlighting its potential role as a prognostic imaging marker in acute ischemic stroke (AIS).</p><p><strong>Methods: </strong>A systematic search was conducted in the MEDLINE, Embase, Cochrane Library, and Web of Science databases to identify studies evaluating the outcomes of EVF following reperfusion therapy in cases of AIS. The outcomes included hemorrhagic transformation (HT), parenchymal hematoma (PH), hemorrhagic infarction (HI), symptomatic intracranial hemorrhage (sICH), cerebral infarction as hypodensity on imaging, malignant brain edema (MBE), and unfavorable outcome measured by modified Rankin scale (mRS ≥ 3) after 90 days. A meta-analysis using a random-effects model was conducted to pool the data.</p><p><strong>Results: </strong>In the data analyses of 12 studies and 2,446 patients, the presence of EVF post-reperfusion was associated with increased risks of HT (odds ratio [OR] = 4.31; 95% confidence interval [CI] [3.00, 6.21]; p < 0.001), PH (OR = 5.73; 95% CI [2.82, 11.65]; p < 0.001), sICH (OR = 6.43; 95% CI [3.49, 8.47]; p < 0.001), cerebral infarction (OR = 15.95; 95% CI [6.37, 39.92]; p < 0.001), MBE (OR = 3.69; 95% CI [2.26, 6.04]; p < 0.001), and unfavorable functional outcomes (OR = 2.58; 95% CI [1.27, 5.23]; p = 0.009).</p><p><strong>Conclusions: </strong>EVF may serve as a predictor of increased risk of hemorrhagic events, cerebral infarction on imaging, MBE, and unfavorable functional outcomes after brain reperfusion therapy.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measuring cerebrovascular reactivity with breath-hold fMRI in patients with Moyamoya angiopathy: MR perfusion based delay correction significantly improves agreement to [¹⁵O]water PET.","authors":"Leonie Zerweck, Uwe Klose, Constantin Roder, Deborah Staber, Emely Renger, Ganna Blazhenets, Kathrin Grundmann-Hauser, Philipp T Meyer, Ulrike Ernemann, Till-Karsten Hauser","doi":"10.1007/s00234-025-03649-3","DOIUrl":"10.1007/s00234-025-03649-3","url":null,"abstract":"<p><strong>Purpose: </strong>Breath-hold functional MRI (bh-fMRI) is able to quantify cerebrovascular reactivity. Vessel stenoses can lead to delayed hemodynamic responses. We aimed to investigate whether delay correction improves the quality of bh-fMRI compared to the diagnostic standard [¹⁵O]water PET.</p><p><strong>Methods: </strong>The bh-fMRI data sets of 25 patients with Moyamoya Angiopathy were analyzed retrospectively without and with delay correction. Delay correction was calculated using time-to-peak (TTP) maps derived from dynamic susceptibility contrast (DSC) perfusion MRI. [¹⁵O]water PET maps and bh-fMRI maps without and with delay correction were presented blinded for delay correction to two neuroradiologists. The agreement between bh-fMRI without and with delay correction and [¹⁵O]water PET was independently and consensually rated on a 4-point-Likert scale (1 = poor, 2 = moderate, 3 = good, 4 = excellent) and compared with Wilcoxon signed-rank test.</p><p><strong>Results: </strong>The agreement between bh-fMRI and [¹⁵O]water PET without delay correction was good/excellent (median = 3, modus = 4), and improved significantly after delay correction with medium effect size (median = 4, modus = 4, z = -2.121, p = 0.034, r = 0.42).</p><p><strong>Conclusion: </strong>Delay correction improves the quality of bh-fMRI and seems to be helpful in clinical practice.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2121-2129"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reverse flow-enhanced catheterization of true lumen in carotid artery dissection: the REFLECT technique.","authors":"Francesco Mistretta, Riccardo Russo, Stefano Molinaro, Umberto Amedeo Gava, Mauro Bergui","doi":"10.1007/s00234-025-03714-x","DOIUrl":"10.1007/s00234-025-03714-x","url":null,"abstract":"<p><p>Endovascular treatment of large vessel occlusion (LVO) caused by carotid artery dissection (CAD) is challenging due to difficulties in identifying and navigating the true lumen. Entering through the false lumen can complicate the procedure, increasing the risk of distal embolization into patent arteries and hindering access to the LVO. We report a case of CAD causing middle cerebral artery (MCA) occlusion, successfully managed with mechanical thrombectomy using a balloon guide catheter. Proximal flow arrest in the dissected carotid artery enabled flow reversal, promoting collapse of the false lumen and improving visualization and access to the true lumen-an approach we term REFLECT technique (Reverse Flow-Enhanced Catheterization of True Lumen in Carotid Artery Dissection). Once the guiding catheter was advanced into the distal healthy carotid segment, intracranial circulation was revascularized. Carotid stents were then deployed within the true lumen to reconstruct the dissected artery and maintain long-term patency.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2205-2209"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144659752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A bicentric study on the prevalence and clinical relevance of subarachnoid hyperdensities on flat-detector CT after thrombectomy in dominant, co-dominant, and non-dominant M2 occlusions.","authors":"Mousa Zidan, Bettina Lara Serrallach, Mattia Branca, Felix Bode, Eike Piechowiak, Thomas Meinel, Nils Christian Lehnen, Tomas Dobrocky, Johannes Kaesmacher, Franziska Dorn","doi":"10.1007/s00234-025-03679-x","DOIUrl":"10.1007/s00234-025-03679-x","url":null,"abstract":"<p><strong>Background: </strong>Subarachnoid hyperdensities (SH) on flat-detector CT (FDCT) after mechanical thrombectomy (MT) are associated with less favorable clinical outcomes. We aimed to further elucidate the prevalence and clinical significance of SH following MT, especially in patients with dominant, co- and non-dominant M2 occlusions.</p><p><strong>Methods: </strong>728 patients from two comprehensive stroke centers were assessed for the presence of SH on FDCT. The primary outcome was the presence of SH on FDCT. The secondary outcome was modified Rankin Scale scores (mRS) at 90 days. Baseline procedural characteristics and clinical outcomes were analyzed using group comparisons and multivariable logistic regression. To remove the effect of confounding factors, a logistic regression model was built using inverse probability weighting.</p><p><strong>Results: </strong>In total, 411 patients were included. Prevalence of SH on FDCT was 171/411 (41.6 %), with particularly high prevalence in co- and non-dominant M2 occlusions (63%) and dominant M2 occlusions (53.9%). The occurrence of SH was independently associated with poor functional outcomes (adjusted OR for mRS at 90 days: 1.5; 95% CI, 1.1-2.2) and increased mortality (aOR: 1.7; 95% CI, 1.0-2.8). Increased risk of developing SH was particularly evident in patients with co- and non-dominant M2 occlusions (P < 0.001 OR = 3.78; 95% CI, 2.18-6.57) and dominant M2 occlusions (P < 0.001 OR = 3.07; 95% CI, 1.68-5.59) compared to large vessel occlusions. A higher number of device passes, specifically between 3 and 6 and more than 6, show an effect on the occurrence of SH P < 0.001 OR = 2.75; 95% CI, 1.56-4.84 and P = 0.02 OR = 3.45; 95% CI, 1.17-10.16 compared to fewer passes (1-3).</p><p><strong>Conclusion: </strong>SH are common after MT, especially in M2 occlusions. They are associated with poorer functional outcomes in patients with co- and non-dominant M2 occlusions and higher numbers of device passes (>3).</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2155-2165"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CBCT-to-CT synthesis with a hybrid of CycleGAN and latent diffusion.","authors":"Feng Luo, Chaoyu Ma, Juntian Shi, Kunyuan Xu","doi":"10.1007/s00234-025-03634-w","DOIUrl":"10.1007/s00234-025-03634-w","url":null,"abstract":"<p><strong>Introduction: </strong>Cone-beam computed tomography (CBCT) is instrumental in image-guided radiation therapy (IGRT), providing low radiation exposure while continuously monitoring anatomical structures for accurate dose estimation and treatment. Despite these advantages, CBCT inherently suffers from lower image quality and more frequent artifacts compared to computed tomography (CT), significantly undermining its effectiveness in IGRT. These drawbacks are especially pronounced in the pelvic region, where anatomical variability and dataset asymmetry challenge traditional image translation techniques like diffusion and CycleGAN networks.</p><p><strong>Methods: </strong>To overcome these limitations, we propose CycleDiffSmoothGAN(CDSGAN), an innovative framework that enhances CBCT images by integrating CycleGAN with latent diffusion techniques and high-frequency detail preservation.This approach effectively blends features in the latent space, enabling smoother transitions between CBCT and synthetic CT (sCT) images.</p><p><strong>Results: </strong>The implementation of CDSGAN has shown superior performance, significantly outperforming existing technologies across crucial imaging metrics such as MAE ( <math><mrow><mn>18.53</mn> <mo>±</mo> <mn>3.58</mn></mrow> </math> Hu), PSNR ( <math><mrow><mn>26.90</mn> <mo>±</mo> <mn>1.53</mn></mrow> </math> dB), SSIM ( <math><mrow><mn>0.90</mn> <mo>±</mo> <mn>0.03</mn></mrow> </math> ), and FID ( <math><mrow><mn>9.84</mn> <mo>±</mo> <mn>1.21</mn></mrow> </math> ).</p><p><strong>Conclusion: </strong>The research findings have substantiated the promising potential of CDSGAN in enhancing image quality for clinical applications.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":"2083-2096"},"PeriodicalIF":2.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}