Odontology最新文献_第3页

Evaluating key predictors of anatomical complexity in mandibular incisors: insights from CBCT analysis considering premolar anatomy, sex, and age.

IF 1.9 3区医学

Odontology Pub Date : 2025-01-30 DOI: 10.1007/s10266-025-01062-z

Breno Araujo Borges Castro, Bruno Guimarães Costa, Francielle Silvestre Verner, Lílian Azevedo de Souza, Rafaela Caires Santos, Rafael Binato Junqueira

{"title":"Evaluating key predictors of anatomical complexity in mandibular incisors: insights from CBCT analysis considering premolar anatomy, sex, and age.","authors":"Breno Araujo Borges Castro, Bruno Guimarães Costa, Francielle Silvestre Verner, Lílian Azevedo de Souza, Rafaela Caires Santos, Rafael Binato Junqueira","doi":"10.1007/s10266-025-01062-z","DOIUrl":"https://doi.org/10.1007/s10266-025-01062-z","url":null,"abstract":"Understanding the impact of premolar root anatomy, sex, and age on incisor complexity can aid in developing tailored diagnostic and therapeutic strategies. This study evaluated if the anatomical complexity of mandibular premolars, sex and age can predict the anatomical complexity in mandibular incisors. Using CBCT scans, 3944 mandibular incisors from 493 patients were analyzed. Intra and inter-examiner reproducibility was confirmed using weighted Kappa tests. A mixed predictive model was employed to assess whether premolar root anatomy, sex, or age could predict incisor complexity (α = 0.05). The variables that influenced the presence of complex anatomical morphology in central and lateral incisors were 2nd premolar, 1st premolar and sex, increasing the odds that the central incisors had a complex anatomical morphology in 2.16, 1.69 and 0.47 times, respectively. These odds increased 1.86, 1.92 and 0.69 times, respectively for lateral. There was no age association with incisor complexity, suggesting that anatomical complexity is primarily influenced by fixed structural characteristics rather than age-related changes. The anatomical complexity of mandibular premolars and the sex (male) were able to predict the occurrence of anatomical complexity in mandibular incisors.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

S100A8 regulates postoperative responses following tooth extraction in rats.

IF 1.9 3区医学

Odontology Pub Date : 2025-01-29 DOI: 10.1007/s10266-025-01056-x

Xinyu Zhao, Jian Liu, Chaoran Jin, Kexu Pan, Yi Du, Zhibin Zuo, Xijiao Yu

{"title":"S100A8 regulates postoperative responses following tooth extraction in rats.","authors":"Xinyu Zhao, Jian Liu, Chaoran Jin, Kexu Pan, Yi Du, Zhibin Zuo, Xijiao Yu","doi":"10.1007/s10266-025-01056-x","DOIUrl":"https://doi.org/10.1007/s10266-025-01056-x","url":null,"abstract":"The reduction in alveolar ridge height and width after tooth extraction poses a substantial challenge for dental implant restoration. This study aimed to observe the roles of S100A8 in the inflammatory response and bone resorption following tooth extraction. Rat mandibular second molars were extracted. Western blotting, micro-computed tomography, tartrate-resistant acid phosphatase staining, immunohistochemistry, scanning electron microscopy (SEM), and immunofluorescence were applied to observe inflammatory responses and bone resorption after rat mandibular second molar extraction. S100A8 was overexpressed in RAW 246.7 cells, and transfection efficiency was confirmed using western blotting and immunofluorescence. Receptor Activator for Nuclear Factor-κB Ligand (RANKL)-induced osteoclastogenesis of RAW 246.7 cells and a lipopolysaccharide-stimulated environment were chosen to evaluate the roles and related mechanisms of S100A8. An increase in S100A8 expression was observed 2 weeks after molar extraction compared to normal gingival tissues. Subsequently, S100 expression decreased between the second and third weeks, coinciding with the progression of inflammatory response following tooth extraction. Positive S100A8 expression was detected in the infiltrating cells and osteoclasts. S100A8 overexpression in RAW 246.7 cells promoted tumor necrosis factor-α expression and osteoclast formation by activating nuclear factor (NF)-κB p65 signaling. In summary, S100A8 was involved in inflammatory responses and bone resorption following tooth extraction by activating NF-κB p65 signaling. Interventions targeted to decrease S100A8 levels may have therapeutic implications for minimizing post-extraction bone loss.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The involvement of orexin-1 receptors in modulation of feeding and anxiety-like behavior in rats with complete Freund's adjuvant-induced temporomandibular joint disorder.

IF 1.9 3区医学

Odontology Pub Date : 2025-01-23 DOI: 10.1007/s10266-024-01021-0

Mojtaba Hosaini, Mehdi Abbasnejad, Razieh Kooshki, Saeed Esmaeili-Mahani, Maryam Raoof, Reyhaneh Naderi, Ghizlane Aarab, Frank Lobbezoo

{"title":"The involvement of orexin-1 receptors in modulation of feeding and anxiety-like behavior in rats with complete Freund's adjuvant-induced temporomandibular joint disorder.","authors":"Mojtaba Hosaini, Mehdi Abbasnejad, Razieh Kooshki, Saeed Esmaeili-Mahani, Maryam Raoof, Reyhaneh Naderi, Ghizlane Aarab, Frank Lobbezoo","doi":"10.1007/s10266-024-01021-0","DOIUrl":"https://doi.org/10.1007/s10266-024-01021-0","url":null,"abstract":"Orexin-A (OXA), a neuropeptide produced in the hypothalamus, is recognized for its role in modulating orofacial nociception and regulating feeding behaviors, as well as its impact on psychophysiological responses. This study investigated the role of orexin-1 receptors (OX1R) in modulating nociceptive behaviors induced by noxious stimulation of the temporomandibular joint (TMJ) and the associated changes in mood and feeding behaviors in rats with complete Freund's adjuvant (CFA)-induced temporomandibular disorders (TMDs). Bilateral cannulation of the lateral ventricles was performed in rats. To induce nociception, CFA was injected unilaterally into the left TMJ of the rats. Nociceptive behaviors were assessed using the hot plate and tail flick tests, while anxiety-like behavior and food intake were evaluated using an elevated plus maze (EPM) and a food preference device, respectively. The results demonstrated a significant increase in nociceptive scores and anxiety-like behaviors, along with reductions in water and food consumption following CFA injection. However, post-treatment with OXA at concentrations of 50 and 100 pM/rat significantly decreased thermal nociceptive scores, alleviated anxiety-like behavior, and increased water and food intake. These beneficial effects were reversed when OXA was co-administered with SB-334867 (40 nM/rat), an OX1R antagonist. Collectively, our findings suggest that OX1R signaling plays a role in the modulation of anxiety-like behavior and abnormalities in food intake in CFA-treated rats. Understanding the involvement of OXA and its receptors in CFA-induced TMJ nociception and behavioral changes may pave the way for potential therapeutic interventions targeting OX1R signaling in the management of TMD-associated symptoms.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the anti-inflammatory, antioxidant and wound healing effects of pterostilbene in human gingival fibroblasts in vitro. 紫檀芪对人牙龈成纤维细胞抗炎、抗氧化及伤口愈合作用的体外评价。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-21 DOI: 10.1007/s10266-024-01052-7

Mukaddes Yerebakan, Gulay Tuter, Emin Umit Bagriacik, Nihan Oruklu, Tugce Guldurur

{"title":"Evaluation of the anti-inflammatory, antioxidant and wound healing effects of pterostilbene in human gingival fibroblasts in vitro.","authors":"Mukaddes Yerebakan, Gulay Tuter, Emin Umit Bagriacik, Nihan Oruklu, Tugce Guldurur","doi":"10.1007/s10266-024-01052-7","DOIUrl":"https://doi.org/10.1007/s10266-024-01052-7","url":null,"abstract":"We aimed to investigate the wound-healing, antioxidant, and anti-inflammatory effects of pterostilbene (PTS) on human gingival fibroblasts (GF). Different concentrations of PTS were applied to GFs and cell viability was evaluated by MTT assay. GFs were stimulated by lipopolysaccharide (LPS) and the study groups were determined as LPS, LPS + 1 μM PTS, LPS + 10 μM PTS, and control. The most effective PTS concentrations were applied in a wound-healing model, with cell counts in the wound area assessed at 0, 24, 48, and 72 h. The effect of PTS on the release of interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), transforming growth factor-β (TGF-β), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), basic fibroblast growth factor (bFGF), and collagen type I (COL I) was assessed at 24 and 48 h by ELISA. The data was statistically analyzed. Our results showed that PTS had a dose-dependently negative effect on wound healing and cell proliferation at 10 μM concentration, but not at low concentration (1 μM). PTS exhibited a potent anti-inflammatory effect by reducing IL-6 and TNF-α levels, while also enhancing antioxidant activity, as evidenced by increased GSH-Px levels in the LPS + 1 μM PTS group (P < 0.05). According to our results, PTS could be a potential and promising substance with anti-inflammatory and antioxidant effects on LPS-stimulated GF. Therefore our results have merit in terms of providing pioneering data for future studies.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of a novel motion and simultaneous irrigation on the cyclic fatigue resistance of Hyflex EDM OneFile. 新型运动和同步灌水对Hyflex EDM OneFile抗循环疲劳性能的影响。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-13 DOI: 10.1007/s10266-024-01051-8

Giusy Rita Maria La Rosa, Pietro Lombardo, Luigi Generali, Eugenio Pedullà

{"title":"Effect of a novel motion and simultaneous irrigation on the cyclic fatigue resistance of Hyflex EDM OneFile.","authors":"Giusy Rita Maria La Rosa, Pietro Lombardo, Luigi Generali, Eugenio Pedullà","doi":"10.1007/s10266-024-01051-8","DOIUrl":"https://doi.org/10.1007/s10266-024-01051-8","url":null,"abstract":"The aim of this study was to assess the cyclic fatigue resistance of a single-file system (i.e., Hyflex EDM OneFile), during continuous rotation and reflex dynamic motion with and without irrigation. Cyclic fatigue tests were conducted on 48 new Hyflex EDM One files using two different motions, with and without irrigation. The files were randomly assigned to four groups (n = 12) based on the tested motion and irrigation conditions: continuous rotation and the novel kinematics ReFlex Dynamic motion, with and without irrigation. The dynamic fatigue resistance was measured as the number of cycles to fracture (NCF) in an artificial zirconium canal with a 60° angle and a 5 mm radius of curvature at an intracanal temperature. The results were analyzed using the non-parametric Mann-Whitney test, with a significance level established at 5% (p < 0.05). The fractured instruments were examined with a scanning electron microscope. The instruments activated in continuous rotation, irrespective of irrigation conditions, demonstrated significantly higher NCF compared to those in ReFlex Dynamic (p < 0.05). Irrigation significantly impacted the cyclic fatigue resistance of Hyflex EDM in ReFlex Dynamic motion (p < 0.05), while it did not influence the resistance of files tested under continuous rotation (p > 0.05). Within the limitations of this in vitro study, HyFlex EDM One files tested under continuous rotation showed greater resistance to cyclic fatigue compared to those tested with ReFlex Dynamic motion, regardless of irrigation. Continuous hypochlorite irrigation enhanced the cyclic fatigue resistance only of the files tested in ReFlex Dynamic motion.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142979467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Osteogenic potential of silver nanoparticles in critical sized mandibular bone defects: an experimental study in white albino rats. 银纳米颗粒在颌骨缺损中的成骨潜能：白化大鼠的实验研究。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-10 DOI: 10.1007/s10266-024-01049-2

Gehad Mohamed Sabry, Nessma Sultan, Mazen Tharwat Abouelkhier, Essam Farouk Soussa

{"title":"Osteogenic potential of silver nanoparticles in critical sized mandibular bone defects: an experimental study in white albino rats.","authors":"Gehad Mohamed Sabry, Nessma Sultan, Mazen Tharwat Abouelkhier, Essam Farouk Soussa","doi":"10.1007/s10266-024-01049-2","DOIUrl":"https://doi.org/10.1007/s10266-024-01049-2","url":null,"abstract":"Natural bone is a self-regenerating nanocomposite made of proteins and minerals. Such self-regenerative capacity can be negatively affected by certain diseases involving the bone or its surrounding tissues. Our study assesses the ability of bone grafting material to regenerate bone in animals who have artificially created critical-sized defects. Nanohydroxyapatite (HANPs) and silver nanoparticles (AgNPs) were synthesized and underwent characterization by transmission electron microscopy. The cytotoxic effect of the nanomaterials was evaluated by MTT assay using bone marrow mesenchymal stem cells (BMMSCs). Five mm critical size defects in white albino rats were utilized to assess the material's biocompatibility, and regenerative capacity. Histological and immunohistochemical analyses using collagen-I and tumor necrotic factor-alpha were also performed. Clinically, the tested materials did not cause any pathological changes. MTT results suggested that both materials showed high biocompatibility. Gel form of AgNPs achieved bone regenerative potential and anti-inflammatory effect being significantly higher than what was seen in HANPs after 21 days post-surgically. The utilization of AgNPs to improve anti-inflammatory and osteoregenerative activities was the primary research outcome of this study. AgNPs have the potential to be useful biomaterial in accelerating bone healing process.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142952424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dysregulation of LINC01094 is involved in the pathogenesis of pulpitis by regulating the miR-340-5p expression. LINC01094基因异常通过调控miR-340-5p的表达参与牙髓炎的发病过程。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-09 DOI: 10.1007/s10266-024-01046-5

Yuao Huang, Tao Su

{"title":"Dysregulation of LINC01094 is involved in the pathogenesis of pulpitis by regulating the miR-340-5p expression.","authors":"Yuao Huang, Tao Su","doi":"10.1007/s10266-024-01046-5","DOIUrl":"https://doi.org/10.1007/s10266-024-01046-5","url":null,"abstract":"Pulpitis seriously affects people's living standards and dental health, so identifying effective therapeutic targets is crucial for pulpitis. The research aimed to explore the underlying regulatory mechanism of LINC01094 and miR-340-5p in pulpitis. The study involved a total of 173 subjects (97 pulpitis and 76 healthy individuals). The expression of LINC01094 and miR-340-5p were evaluated through the polymerase chain reaction (PCR). The association linking LINC01094 and miR-340-5p expression was assessed by Pearson correlation analysis. The Human dental pulp cells (HDPCs) injury model was conducted by lipopolysaccharide (LPS). Cell proliferation was examined through the Cell Counting Kit-8 assay and flow cytometry. Cell apoptosis was also evaluated by flow cytometry. The caspase-3 levels and inflammatory cytokines were quantified using an enzyme-linked immunosorbent assay (ELISA). Upregulated LINC01094 and downregulated miR-340-5p expression were observed in pulpitis and LPS-induced HDPC injury models. A negative correlation was observed between miR-340-5p and LINC01094 expression in pulpitis. LPS could suppress proliferation and promote apoptosis of HDPCs. The TNF-α, IL-6, and IL-1β levels in LPS-induced HDPCs were also elevated. The HDPC injury induced by LPS could be aggravated by the LINC01094 overexpression. MiR-340-5p showed a relieved effect on HDPC injury and could alleviate the HDPC injury aggravated by LINC01094 overexpression. In summary, upregulated LINC01094 and downregulated miR-340-5p expression was observed in pulpitis. LINC01094 could accelerate the pulpitis progression via targeting miR-340-5p.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142952422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transcriptional regulation of human follicular dendritic cell-secreted protein gene by interleukin-6. 白细胞介素-6对人滤泡树突状细胞分泌蛋白基因的转录调控。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-08 DOI: 10.1007/s10266-024-01050-9

Zhenyu Jin, Yuto Tsuruya, Kazuma Igarashi, Arisa Yamaguchi, Hideki Takai, Yohei Nakayama, Yorimasa Ogata

{"title":"Transcriptional regulation of human follicular dendritic cell-secreted protein gene by interleukin-6.","authors":"Zhenyu Jin, Yuto Tsuruya, Kazuma Igarashi, Arisa Yamaguchi, Hideki Takai, Yohei Nakayama, Yorimasa Ogata","doi":"10.1007/s10266-024-01050-9","DOIUrl":"https://doi.org/10.1007/s10266-024-01050-9","url":null,"abstract":"Follicular dendritic cell-secreted protein (FDC-SP) is produced by follicular dendritic cells, periodontal ligament and junctional epithelium (JE). JE exists immediately apical to the bottom of the pocket and binds enamel with hemidesmosomes to protect the periodontium from bacterial infection. To analyze the transcriptional regulation of the FDC-SP gene by interleukin-6 (IL-6), we performed real-time PCR, Western blotting, immunofluorescence, luciferase (LUC) assays, gel mobility shift and chromatin immunoprecipitation (ChIP) assays using Ca9-22 and Sa3 gingival epithelial cells. IL-6 increased FDC-SP mRNA and protein levels at 3-24 h. IL-6 increased LUC activities of the LUC constructs containing FDC-SP gene promoter sequences from -116 to -717 bp upstream from the transcriptional start site. IL-6 induced LUC activities of -345FDCSP were inhibited by protein kinase A, tyrosine kinase, mitogen-activated protein kinase kinase, phosphoinositide 3-kinase, signal transducer, activator of transcription 3 (STAT3) and glycoprotein 130 inhibitors. Gel shift and ChIP assays showed that IL-6 induced Yin Yang1 (YY1), GATA binding protein (GATA), CCAAT/enhancer-binding protein (C/EBP) β, phosphorylated STAT3 (p-STAT3) binding to YY1, GATA, C/EBP2, C/EBP3 and GAS2-3 elements. These results indicate that IL-6 induces FDC-SP gene transcription YY1, GATA, C/EBP2, GAS2-3 and C/EBP3 elements in the human FDC-SP gene promoter, and suggesting that FDC-SP may be involved in the defense against JE in periodontium during the progression of periodontitis.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142952426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dental maxillary sinus pathology: a CBCT-based case-control study. 上颌窦病理：一项基于cbct的病例对照研究。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-04 DOI: 10.1007/s10266-024-01045-6

João Carlos Monteiro Castro, José Luiz Cintra Junqueira, Cleomar Donizeth Rodrigues, Glaucia Nize Martins Santos, Clarissa Rocha Martinez, Francine Kühl Panzarella

{"title":"Dental maxillary sinus pathology: a CBCT-based case-control study.","authors":"João Carlos Monteiro Castro, José Luiz Cintra Junqueira, Cleomar Donizeth Rodrigues, Glaucia Nize Martins Santos, Clarissa Rocha Martinez, Francine Kühl Panzarella","doi":"10.1007/s10266-024-01045-6","DOIUrl":"https://doi.org/10.1007/s10266-024-01045-6","url":null,"abstract":"This study evaluated the association between dental infection and maxillary sinus pathology, and the influence of age, sex, type of tooth, root proximity to the sinus floor, the condition of the primary maxillary ostium, and the presence of an accessory maxillary ostium in this process. Computed Tomography scans were selected, and upper posterior teeth were evaluated for the presence of apical periodontitis (AP), bone loss with furcation involvement, and endoperiodontal lesion (EPL), subsequently, sinuses were evaluated for mucosal thickening (MT) and opacification of the maxillary sinus (OMS). Logistic regression models were constructed, and Chi-squared and Fisher's tests were applied. Patients with AP were 15.63 times (7.576;32.268) and, 25.97 times (16.22,41.56) more likely to have MT and OMS, respectively. No teeth were associated with EPL in the group without sinus pathology, indicating a strong association with OMS. Male patients were 1.30 times more likely to have MT, and 5.86 times more likely to have OMS than female patients. The condition of the ostium, presence of an accessory ostium, type of tooth, and proximity of the root to the sinus floor were not associated with MT or OMS. In conclusion, male sex and the presence of AP and EPL are associated with maxillary sinus pathology.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Palatal symmetry analysis of surgical protocols for oral clefts by 3D stereophotogrammetry. 用三维立体摄影测量法分析唇腭裂手术方案的腭对称性。

IF 1.9 3区医学

Odontology Pub Date : 2025-01-03 DOI: 10.1007/s10266-024-01048-3

Mariel Tavares Oliveira Prado Bergamo, Eloá Cristina Passucci Ambrosio, Cleide Felício de Carvalho Carrara, Maria Aparecida Andrade Moreira Machado, Thais Marchini Oliveira

{"title":"Palatal symmetry analysis of surgical protocols for oral clefts by 3D stereophotogrammetry.","authors":"Mariel Tavares Oliveira Prado Bergamo, Eloá Cristina Passucci Ambrosio, Cleide Felício de Carvalho Carrara, Maria Aparecida Andrade Moreira Machado, Thais Marchini Oliveira","doi":"10.1007/s10266-024-01048-3","DOIUrl":"https://doi.org/10.1007/s10266-024-01048-3","url":null,"abstract":"This study aimed to compare the dimensional alterations of the dental arches and the palate symmetry in patients with unilateral complete cleft lip and palate before and after the performance of primary surgeries by different surgical techniques. The sample was divided into Group 1, G1 - cheiloplasty (Millard technique) and single-stage palatoplasty (von Langenbeck technique); Group 2, G2 - cheiloplasty (Millard technique) and two-stage palatoplasty (Hans Pichler and Sommerlad techniques). The digital dental models were evaluated before (Time 1, T1) and after (Time 2, T2) primary surgeries. The straight linear (I-C, I-T, C-T, I-C', I-T', C'-T') and angular measurements (< ICT, < CTT', < IC'T', < C'T'T) were performed. Statistical analysis was applied with α = 5%. In the intragroup analysis, G1 and G2 showed a significant increase in T2 for all linear parameters except I-C' and I-T' and a decrease in all angular parameters except for < IC'T' in G1 and < CTT' in G2. In the intergroup analysis, at T2, there was an increase in C-T and I-T' and a decrease in < ICT for G2. Regarding the asymmetry in T1, for G1 and G2, we observed asymmetry in I-C vs I-C', I-T vs I-T', C-T vs C'-T', and < CTT' vs < C'T'T analyses. At T2, we observed asymmetry in all parameters except for I-T vs I-T' in G1 and for C-T vs C'-T' in G2. It is concluded that in following single-stage palatoplasty, there is symmetry in the total segment length, while two-stage palatoplasty is specifically effective in preserving symmetry in the posterior segment length.","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142922366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0