Odontology最新文献

{"title":"Garlic as a novel therapeutic agent for the management of pulp infections: a systematic review.","authors":"Renata de Oliveira Alves, Isabela Maria Passarela Gomes, José Roberto Vergínio de Matos, Alexandre Henrique Dos Reis-Prado, Geórgia Rondó Peres, Priscila Toninatto Alves de Toledo, Marcelle Danelon, Gabriel Pereira Nunes","doi":"10.1007/s10266-026-01389-1","DOIUrl":"https://doi.org/10.1007/s10266-026-01389-1","url":null,"abstract":"<p><p>In vitro studies have shown that garlic extracts are effective against microorganisms commonly associated with root canal infections, with the ability to penetrate bacterial biofilms and inhibit the growth of resistant strains. Building upon this preclinical evidence, the objective of the present systematic review was to identify, critically analyze, and synthesize the available clinical trials on the efficacy of garlic as a therapeutic agent in the management of pulp infections. The review was conducted following PRISMA guidelines and registered in PROSPERO, including clinical trials evaluating garlic-based treatments. A literature search was performed, studies were screened, data extracted, and the risk of bias was assessed using the Cochrane tool and the Newcastle-Ottawa Scale. Certainty of evidence was graded with the GRADE approach. Sixteen studies were included, of which 13 evaluated garlic-derived compounds as intracanal medicaments. Clinical success rates were generally high (≥ 90%), with outcomes comparable to formocresol and MTA, and at lower costs. Radiographic success ranged from 55% to 100%, with some studies showing superior results in reducing periapical signs. Microbiological analyses demonstrated a significant short-term reduction in bacterial load, with superior efficacy compared to conventional agents. Three additional studies investigated garlic-based irrigants, reporting moderate-to-high clinical success (around 75%). Overall, the included studies demonstrated a low risk of bias. The certainty of evidence was rated as moderate for randomized controlled trials and low for non-randomized trials. Low-to-moderate certainty evidence suggests garlic-derived formulations may improve clinical and radiographic outcomes when used as irrigants or intracanal medicaments in pulpotomy and pulpectomy procedures in endodontic practice. However, evidence remains limited, and well-designed, standardized clinical trials with long-term follow-up are needed to confirm their efficacy and safety.</p>","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147691337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical effectiveness of albumin-enriched platelet-rich fibrin (Alb-PRF) in periodontal and peri-implant regenerative surgery: a systematic review.","authors":"Halil Ata Bıçakçıoğlu, Gülenay Çolak","doi":"10.1007/s10266-026-01388-2","DOIUrl":"https://doi.org/10.1007/s10266-026-01388-2","url":null,"abstract":"<p><p>Alb-PRF is a heat-induced autologous fibrin biomaterial generated by combining thermally denatured serum albumin with liquid platelet-rich fibrin. Although its clinical use in periodontal and peri-implant procedures has increased, the available evidence remains limited and methodologically heterogeneous. This systematic review aimed to synthesize the biological rationale, clinical effectiveness, and methodological quality of Alb-PRF in periodontal and peri-implant applications. A comprehensive literature search was conducted in PubMed, Scopus, Web of Science, and the Cochrane Library from January 2013 to December 2025 in accordance with PRISMA 2020 guidelines. Grey literature sources, including Google Scholar and OpenGrey, were also screened. Randomized and controlled clinical trials as well as relevant in vivo animal studies evaluating Alb-PRF were included. Study selection and data extraction were independently performed by two reviewers using Rayyan, and methodological quality was assessed using the RoB-2, Newcastle-Ottawa Scale, or SYRCLE tools. Due to substantial heterogeneity in study design, clinical indications, and outcome measures, a narrative synthesis was performed. Seven studies were included (six clinical and one animal study), comprising 156 human participants and 24 animal samples, with follow-up periods ranging from 7 days to 6 months. Alb-PRF showed consistent benefits in early soft-tissue healing and postoperative comfort. However, evidence supporting its role in hard-tissue regeneration remains limited and inconclusive. Based on current evidence, Alb-PRF should be biologically interpreted as a soft-tissue phenotype-modulating adjunct that stabilizes the early healing microenvironment rather than as a primary hard-tissue regenerative material. Its clinical utility appears to be indication-specific and mainly related to early soft-tissue outcomes. Well-designed, standardized randomized controlled trials with longer follow-up periods are required to clarify its therapeutic role. PROSPERO registration number: CRD420251237466 (registered on 21 November 2025, version 1.0).</p>","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147691333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of moderate to heavy occlusal forces and tooth wear on interproximal caries prevalence in posterior teeth.","authors":"Ali Bahrami, Maedeh Doostmohammadi, Aidin Sooratgar, Hossein ChalakiNia","doi":"10.1007/s10266-026-01363-x","DOIUrl":"https://doi.org/10.1007/s10266-026-01363-x","url":null,"abstract":"<p><p>This cross sectional analytical study evaluated whether clinical indicators of occlusal forces are associated with the prevalence of interproximal caries in posterior teeth. A total of 403 posterior teeth from 109 patients (12-70 years) attending Mashhad Dental School were examined. Dental facets, non carious cervical lesions, occlusion type, and contact position were recorded as clinical indicators of occlusal forces, and interproximal caries was assessed clinically and radiographically using ICDAS II criteria. Caries risk status was determined using the CAMBRA system. The association between dental facets and interproximal caries was analyzed using bivariate and multivariable logistic regression, and multilevel logistic regression with teeth nested within subjects to account for clustering. Models were adjusted for gender, plaque presence, occlusion type, and contact position. Dental facets were present in 72.5% of examined teeth, and interproximal caries in 32.5%. Teeth with facets showed a higher prevalence of interproximal caries than teeth without facets (38.7% vs. 16.2%). The presence of facets was strongly associated with interproximal caries in both standard and multilevel models (adjusted odds ratio approximately 3.0; 95% confidence interval roughly 1.7-5.6; p < 0.001). This association persisted across subgroups defined by plaque presence and occlusion type, whereas plaque, occlusion type, contact position, and gender were not independently associated with caries. Teeth with facets were also found in patients with a greater number of extracted teeth. Within the limitations of this cross sectional study, clinical indicators of increased occlusal forces, particularly dental facets, were significantly associated with a higher prevalence of interproximal caries in posterior teeth. These findings support the hypothesis that biomechanical factors may contribute to the development of interproximal caries in addition to traditional biological and behavioral risk factors, but they do not establish a causal relationship. Assessment of occlusal indicators such as wear facets may help identify patients at increased risk of interproximal caries and could be incorporated into caries risk evaluation and preventive planning.</p>","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147675402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do fiber tips with different geometric designs affect intracanal medicament removal in laser-activated irrigation of immature permanent teeth?: an in vitro study.","authors":"Merve Işik Aydin, Amine Yiğit","doi":"10.1007/s10266-026-01390-8","DOIUrl":"https://doi.org/10.1007/s10266-026-01390-8","url":null,"abstract":"<p><p>This in vitro study aimed to evaluate the effects of fiber tips with different geometric designs on the removal of intracanal medicaments during laser-activated irrigation (LAI) in immature permanent teeth. A total of 110 mandibular premolars were prepared using standardized procedures to simulate immature permanent tooth models. The teeth were randomly assigned to two groups according to the intracanal medicament applied. Calcium hydroxide (CH) and double antibiotic paste (DAP) were removed using standard needle irrigation (SNI) and LAI protocols, namely PIPS and SWEEPS, with two different fiber-tip end designs: flat (F) and radial (R). After irrigation, the specimens were examined under a stereomicroscope and digital images were obtained. The efficacy of medicament removal was quantitatively assessed by calculating the percentage area of residual medicament within the canal space using image analysis software (ImageJ). A significant difference was observed between the CH and DAP groups in terms of residual medicament levels (p < 0.05), with lower residue values in the CH group. Significant differences were also found among the irrigation activation protocols (p < 0.05). SNI showed the lowest removal efficiency, whereas SWEEPS-R resulted in the lowest residual medicament values. Within the limitations of this in vitro study, the SWEEPS-R protocol showed the highest removal efficiency for both CH and DAP, whereas SNI resulted in the greatest amount of residual medicament. CH was removed more effectively than DAP, and none of the tested protocols achieved complete removal. Understanding the influence of fiber-tip geometry on medicament removal may help guide the selection of more effective LAI protocols for regenerative endodontic procedures in immature permanent teeth.</p>","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147675415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro comparative evaluation of bioactive glass and fluoride varnishes on enamel remineralization of permanent teeth.","authors":"Inas Karawia, Rania Adel Naguib, Marina Nabil Rafla, Alaa Emad Abdel Fattah, Sandra Maged Michael, Osama Safwat Mohamed","doi":"10.1007/s10266-026-01375-7","DOIUrl":"https://doi.org/10.1007/s10266-026-01375-7","url":null,"abstract":"<p><p>Bioactive glass, a material capable of precipitating hydroxyapatite in aqueous solutions, has the unique ability to bond with both hard and soft tissues without causing rejection. This study aimed to compare the effectiveness of bioactive glass varnish to fluoride varnish in promoting enamel remineralization in extracted teeth. Thirty human premolars were collected, then cleaned and polished using a scaler. The teeth were sectioned longitudinally, and the roots were removed. The specimens were stored in a demineralizing solution to create early enamel lesions and then randomly divided into three groups: bioactive glass varnish, fluoride varnish, and a control group. The materials were applied, and all specimens underwent a pH-cycling model for 1 month. Enamel evaluation was conducted using DIAGNOdent, and SEM-EDAX to measure calcium and phosphorus weight percentages, and surface roughness was assessed. Data were analyzed accordingly. The results show that at baseline and after demineralization, there were no significant differences in DIAGNOdent readings among the three groups, but significant changes were observed within each group from baseline to after demineralization (p ≤ 0.05). After treatment, the bioactive glass varnish group showed significantly the lowest DIAGNOdent readings, followed by the fluoride varnish group, while the control group showed the highest readings (p ≤ 0.05). EDAX analysis revealed significantly higher calcium and phosphate mass percentages in the bioactive glass group compared to the fluoride and control groups (p ≤ 0.05). SEM examination demonstrated a smoother enamel surface in the bioactive glass group, mild irregularities in the fluoride group, and pronounced roughness in the control group. Both bioactive glass and fluoride varnishes demonstrated a remineralizing effect on enamel surfaces. However, the bioactive glass varnish showed superior performance, with greater mineral gain confirmed by DIAGNOdent, EDAX, and SEM analyses. These findings indicate that bioactive glass varnish may offer an effective and biocompatible alternative to fluoride varnish for managing early enamel lesions.</p>","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147675457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of sodium fluoride addition to an adhesive system on micro tensile bond strength of ceramic occlusal veneer.","authors":"Doaa Shawky Abdelmenam, Waleed Mohamed Elshahawy, Rania Khedr Ahmed","doi":"10.1007/s10266-026-01374-8","DOIUrl":"https://doi.org/10.1007/s10266-026-01374-8","url":null,"abstract":"<p><p>This study aimed to assess the effect of incorporating sodium fluoride (NaF) into an adhesive system on the microtensile bond strength of ceramic occlusal veneers. Eighty resin-dentin sticks (~ 1 mm²) were obtained from 20 upper first premolars, with each tooth yielding four sticks. The teeth were sectioned using an Isomet saw to expose deep dentin, and Vita Enamic occlusal veneers were fabricated and cemented prior to sectioning. The specimens (n = 20) were assigned to two adhesive groups: a control (unmodified adhesive) group and a NaF-containing adhesive group. Each group was further subdivided into two subgroups, which were tested after 24 h and 6 months of storage in artificial saliva at 37 °C. Microtensile bond strength was measured using a universal testing machine. Repeated-measures ANOVA revealed no significant effect of adhesive type or storage duration on tensile bond strength. Independent t test showed a highly significant difference between subgroups I-B and II-B, with no significant differences in other comparisons. Mixed failures predominated across all groups, indicating balanced interfacial and cohesive properties, and EDX confirmed successful fluoride incorporation. Incorporation of sodium fluoride into the adhesive system did not alter immediate dentin bond strength but reduced long-term durability of ceramic partial-coverage restorations.</p>","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147675490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prompt engineering shapes diagnostic accuracy and explanation quality of LLM in oral lesion diagnosis: a prospective, expert-blinded benchmark study.","authors":"Fatma E A Hassanein, Suzan S Ibrahim, Saygo Tomo, Abdulaziz Alsahhaf, Asmaa Abou-Bakr","doi":"10.1007/s10266-026-01380-w","DOIUrl":"https://doi.org/10.1007/s10266-026-01380-w","url":null,"abstract":"<p><p>To evaluate how different prompting strategies influence the diagnostic accuracy, stability, and interpretability of a multimodal large language model (LLM) (ChatGPT-5.1) in oral lesion assessment and to introduce the Prompt Performance Index (PPI), a novel robustness metric that quantifies the performance stability across clinically relevant subgroups. A total of 300 biopsy-confirmed clinical vignettes were assessed using three distinct prompting strategies: a Context-Focused Prompt (CFP), an Evidence-Guided Prompt (EGP), and a Consistency-Optimized Prompt (COP). Diagnostic accuracy (Top-1 and Top-3), confidence calibration, explanation quality, and computational efficiency were compared. The PPI, defined as mean diagnostic accuracy penalized by variability across subgroups, was developed to characterize robustness across diagnostic difficulty tiers and lesion categories. Multivariable regression models examined the independent effects of prompt structure, case difficulty, and lesion type. COP achieved the highest numerical Top-1 accuracy (72.0%) and the greatest performance stability across difficulty levels and lesion categories. Confidence calibration and explanation quality were also superior for COP (p < 0.0001). Multivariable regression analysis confirmed that both prompt design and diagnostic difficulty significantly influenced model accuracy. The PPI differentiated prompting strategies by revealing variation in diagnostic performance stability not captured by accuracy metrics alone, with COP yielding the highest PPI values under both Top-1 and Top-3 performance. Prompt engineering meaningfully affects multimodal LLM diagnostic behavior in oral medicine. The proposed PPI provides a novel and clinically interpretable framework for evaluating diagnostic robustness across heterogeneous clinical conditions, complementing conventional accuracy-based assessments and enabling more dependable diagnostic workflows with AI assistance.</p>","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical properties and micro-CT-based biomechanical performance of NiTi instrumentation systems in mandibular molars.","authors":"Jeneffer Vieira Rodrigues, Julia Godoi-Lopes, Heitor Silva Prado, Anne Rafaella Tenório Vieira, Rafael Verardino Camargo, Graziela Bianchi Leoni, Marco Antonio Hungaro Duarte, Igor Bassi Ferreira Petean, Manoel Damião Sousa-Neto, Murilo Priori Alcalde, Fabiane Carneiro Lopes-Olhê, Jardel Francisco Mazzi-Chaves","doi":"10.1007/s10266-026-01382-8","DOIUrl":"https://doi.org/10.1007/s10266-026-01382-8","url":null,"abstract":"<p><p>This study evaluated the cyclic fatigue, torsional, and bending resistance of five nickel-titanium (NiTi) instrumentation systems and investigated the relationship between these mechanical properties and the biomechanical performance of root canal preparation in mandibular molars using micro-computed tomography (micro-CT). A total of 200 instruments were used. One hundred and fifty new instruments (n = 10 per group, per test) from the Blue Shaper (25.06), VDW Rotate (25.06), ProTaper Ultimate (25.08), ProTaper Next (25.06), and WaveOne Gold (25.07) systems were subjected to cyclic fatigue testing, torsional fatigue testing, and bending resistance evaluation. Fractured surfaces were analyzed under scanning electron microscopy (SEM). Additionally, 50 instruments (10 per group) were used to prepare 50 mandibular molars, which were analyzed by micro-CT to assess 2D and 3D shaping parameters. WaveOne Gold (WOG) and VDW Rotate exhibited the highest cyclic fatigue resistance. VDW Rotate presented the greatest flexibility and the best results related with shaping ability, with higher canal circularity and fewer unprepared walls, indicating a more conservative and centered preparation. Conversely, Blue Shaper (BS), characterized by lower fatigue resistance and greater stiffness, produced the largest dentin removal and volumetric increase. A significant positive relationship was observed between increased flexibility/fatigue resistance and more conservative shaping outcomes. The mechanical properties of NiTi instruments, especially flexibility as indicated by cyclic fatigue and bending resistance, play an important role in predicting biomechanical preparation performance. Systems combining enhanced flexibility through thermomechanical treatment and optimized cross-sectional design provide more conservative and centered shaping, improving clinical safety and efficiency.</p>","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"O-GlcNAcylation of AZGP1 regulates M1/M2 macrophage polarization in diabetic periodontitis.","authors":"Xiaofang Zeng, Hong Xia, Yulong Ma","doi":"10.1007/s10266-026-01387-3","DOIUrl":"https://doi.org/10.1007/s10266-026-01387-3","url":null,"abstract":"<p><p>Macrophage homeostasis is disrupted in periodontitis, a condition often exacerbated by diabetes. AZGP1 is an inflammation-associated factor capable of modulating macrophage polarization. Hyperglycemia alters O-GlcNAcylation dynamics in pathological contexts. This study investigated the regulatory role of AZGP1 in macrophage polarization during diabetic periodontitis and explored whether O-GlcNAcylation mediated this effect. Raw264.7 cells were exposed to lipopolysaccharide (LPS) and high glucose (HG) to simulate the periodontitis and hyperglycemia microenvironment, respectively. Macrophage polarization was analyzed by quantifying M1 and M2 markers via qRT-PCR and immunofluorescence. O-GlcNAcylation of AZGP1 regulated by OGT was examined using immunoprecipitation, immunoblotting, and cycloheximide-chase assays. A hyperglycemic periodontitis mouse model was established, and bone-related parameters and macrophage polarization were assessed. Porphyromonas gingivalis LPS induced M1 polarization and suppressed M2 polarization in Raw264.7 cells, while HG further amplified LPS-driven polarization. Following LPS/HG treatment, AZGP1 expression increased; its knockdown inhibited M1 polarization and enhanced M2 polarization. OGT depletion reduced AZGP1 protein stability by blocking O-GlcNAcylation at the tryptophan (T205) residue. AZGP1 overexpression counteracted the M1/M2 polarization inhibition caused by OGT knockdown. In vivo, AZGP1 knockdown mitigated alveolar bone destruction in periodontitis mice with hyperglycemia by promoting M1 to M2 polarization. O-GlcNAcylation of AZGP1, mediated by OGT, enhances its stability, promoting M1 polarization and suppressing M2 polarization under hyperglycemic conditions, thereby exacerbating periodontitis progression under hyperglycemic conditions. These findings offer novel insights into the pathogenesis and therapeutic strategies for diabetic periodontitis.</p>","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in dental age and masticatory performance during the mixed dentition period.","authors":"Masako Shiramizu, Yoko Hasegawa, Hiroyuki Yoneda, Takafumi Yamamoto, Takahiro Ono","doi":"10.1007/s10266-026-01398-0","DOIUrl":"https://doi.org/10.1007/s10266-026-01398-0","url":null,"abstract":"<p><p>In recent years, the development of masticatory function during growth has become increasingly important. However, only a few studies have objectively evaluated longitudinal changes in masticatory performance during the mixed dentition period. This study aimed to examine the relationship between 1-year changes in dental age and objective masticatory performance in fourth- to sixth-grade elementary school students. The study participants included 434 children (218 boys, age: 9-11 years) in the mixed dentition period (mainly Hellman stages IIIA-IIIC). Oral examinations and masticatory performance measurements were conducted at baseline and at the 1-year follow-up. Oral examinations included assessment of Hellman's dental age (IIIA/IIIB/IIIC/IVA) and the number of permanent and primary teeth. The shearing performance (SP) and mixing performance (MP) were assessed using gummy jellies and color-changing gums, respectively, on a 10-point scale. Statistical analysis was performed using the chi-square, Kruskal-Wallis, and Wilcoxon signed-rank tests. Changes in dental age were observed in 53.5% of the participants, who were classified into nine groups based on the pattern of change (baseline/follow-up). For SP, the IIIB/IVA group showed the greatest increase (p = 0.007), whereas the IIIA/IIIB group showed a decrease, which was not statistically significant (p = 0.053). However, no marked differences in MP were observed between the groups. These results suggest that the changes in masticatory performance over the 1-year period of tooth replacement differ based on the pattern of dental aging, and these changes are influenced by the type of test food used for evaluation.</p>","PeriodicalId":19390,"journal":{"name":"Odontology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}