Nutricion hospitalaria最新文献

{"title":"National expert consensus on the identification of foods with highest antioxidant capacity using a modified Delphi Method.","authors":"Etna Lucero Domínguez-Zambrano, María Luisa Peralta-Pedrero, José Pedraza-Chaverri, Omar Noel Medina-Campos, Samuel Ramos-Acevedo, Ángeles Espinosa-Cuevas","doi":"10.20960/nh.06504","DOIUrl":"10.20960/nh.06504","url":null,"abstract":"<p><strong>Introduction: </strong>Introduction: the total dietary antioxidant capacity (TDAC) is a valuable tool for assessing the antioxidant potential of foods and establishing dietary recommendations across diverse populations and clinical settings. Despite the availability of various methodologies, the Oxygen Radical Absorbance Capacity (ORAC) assay remains one of the most widely used methods internationally. However, existing international food frequency questionnaires often overlook ethnic foods rich in antioxidants that are commonly consumed in Mexico. Objective: to identify which Mexican foods should be prioritized for ORAC measurement, with the goal of developing a FFQ capable of estimating TDAC and applying it to various clinical settings, a modified Delphi consensus was conducted. Methods: a modified Delphi consensus was conducted with a panel of eleven national experts specializing in antioxidant analysis of regional foods. Over three rounds, 27 questions regarding the inclusion of various Mexican foods were evaluated, focusing on fruits, vegetables, legumes, traditional dishes, and beverages. Results: the consensus identified key ethnic foods with significant antioxidant content, such as mango, hibiscus flower, chocolate and regional varieties of coffee and beans, which are not currently represented in international TDAC questionnaires. Conclusions: this expert-driven selection did inform the development of a culturally relevant TDAC questionnaire tailored for application in both healthy populations and clinical contexts, such as patients with chronic kidney disease. The inclusion of these region-specific foods is expected to enhance the accuracy and applicability of antioxidant intake assessments in Mexico, contributing to more precise dietary guidance and clinical management.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"1090-1101"},"PeriodicalIF":1.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148259144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Value of the prognostic nutritional index in wound healing outcomes in elderly patients undergoing total knee arthroplasty].","authors":"Pilar Lalueza Broto, Maria Mercedes Reverté Vinaixa, Rosa Burgos Peláez, Cristina Vaqué Crusellas, Albert Blanco Grau, Irene Portas Torres, Joan Minguell Monyart, Nayana Joshi Jubert","doi":"10.20960/nh.05797","DOIUrl":"10.20960/nh.05797","url":null,"abstract":"<p><strong>Introduction: </strong>Introduction: malnutrition is a modifiable risk factor that is associated with a higher number of post-surgical complications in total knee arthroplasty (TKA), such as delayed healing, persistent drainage and prosthetic infection. The identification of simple and reliable nutritional parameters is key to optimizing the preoperative preparation of elderly patients, a particularly vulnerable group. Aim: the objective of this study was to evaluate the usefulness of the nutritional prognostic index (NPI) and other biochemical parameters as predictors of surgical wound-related complications in patients ≥ 75 years of age undergoing primary TKA. Material and methods: a single-center retrospective observational cohort study was conducted. Patients ≥ 75 years of age who underwent surgery for TKA between January 2016 and December 2019, with nutritional data available in the 6 months prior to surgery, were included. Biodemographic, biochemical (albumin, fibrinogen, creatinine, lymphocytes), clinical (hospital stay, readmissions) variables were analyzed, and combined indices (albumin/lymphocyte ratio, albumin/fibrinogen ratio, NPI) were calculated. Prolonged hospital stay ( > 7 days) and readmission were considered as indicators of postoperative complications. Results: of 584 patients operated on, 117 met inclusion criteria (mean age 79.6 years; 71 males, 46 females). There were 8 readmissions (6.8 %). Patients with albumin < 3.5 g/dl and NPI < 40 had significantly longer stayed (p = 0.004 and p < 0.001, respectively). An NPI < 40 was associated with lower albumin, lymphocyte, and albumin/fibrinogen ratio levels, as well as longer duration of hospitalization (12.8 vs. 6.6 days; p = 0.023). In the analysis of readmissions, only albumin (p = 0.018) and NPI (p = 0.018) showed a significant association. Conclusion: preoperative nutritional assessment could be key to identifying and optimizing the nutritional status of these patients, to reduce postoperative complications. NPI and serum albumin are confirmed as simple and useful nutritional markers to predict postoperative complications in elderly patients undergoing TKA. An NPI value < 40 identifies patients at higher risk of wound complications and prolonged hospital stay, reinforcing the need to incorporate routine nutritional assessment in the preoperative period and to propose specific nutritional interventions in this high-risk group.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"1040-1045"},"PeriodicalIF":1.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal analysis of weight regain after Roux-en-Y gastric bypass ‒ The role of the MTCH2 gene polymorphism and dietary factors.","authors":"Izabella Ferreira Pires, Marcela Augusta de Souza Pinhel, Ligia Moriguchi Watanabe, Luisa Maria Diani, Wilson Salgado-Júnior, Maysa de Araujo Ferreira Julio, Rafael Ferreira Fernandes, Natalia Y Noronha, Carla B Nonino","doi":"10.20960/nh.06238","DOIUrl":"10.20960/nh.06238","url":null,"abstract":"<p><strong>Introduction: </strong>Introduction: Roux-en-Y gastric bypass (RYGB) is a highly effective intervention for morbid obesity; however, significant inter-individual variability in long-term weight outcomes and the phenomenon of weight regain remain clinical challenges. Understanding the genetic and dietary factors influencing these variable responses is crucial for personalized patient management. Objectives: this study aimed to evaluate the influence of single nucleotide polymorphisms (SNPs) on weight loss response in morbidly obese patients undergoing bariatric surgery. Material and methods: adults (n = 108) undergoing RYGB with five-year follow-up were included. Retrospective analysis covered anthropometric, body composition, dietary intake, and biochemical data. Genetic analysis (Illumina® BeadChip) from whole blood DNA identified obesity-related biomarkers. Standard statistical tests (p < 0.05) and bioinformatics software were utilized. Results: significant and sustained improvements were observed across anthropometric and biochemical parameters post-RYGB. However, weight regain became evident from the second postoperative year. The T allele of the MTCH2 gene SNP rs3817334 was found to be prevalent in the cohort (42.4 %). Patients carrying at least one T allele exhibited significantly higher body mass index (BMI) and waist circumference (WC) at specific postoperative time points and a greater percentage of weight regain (> 10 % from nadir weight) at five years post-surgery (p = 0.004) compared to those with the CC genotype. No significant associations were observed with dietary intake or biochemical markers. Conclusions: RYGB promotes substantial long-term weight loss, but weight regain is a notable concern from the second year. The MTCH2 gene SNP rs3817334, particularly its T allele, is associated with higher BMI and WC and contributes to a greater predisposition to long-term weight regain, suggesting its potential as a genetic biomarker for predicting differential responses to bariatric surgery.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"1013-1021"},"PeriodicalIF":1.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147645969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects and reporting quality of the vitamin supplementation on cognitive function in older adults with Alzheimer's disease ‒ A systematic review.","authors":"Camila Álvarez Velásquez, Mauricio Álvarez Mercado, Rosario Negrón López, Carolina Neira-Maldonado, Joaquín Salazar-Méndez, Juan-Carlos Coronado, Iván Cuyul-Vásquez, Felipe Ponce-Fuentes","doi":"10.20960/nh.06434","DOIUrl":"10.20960/nh.06434","url":null,"abstract":"<p><strong>Introduction: </strong>Background: evidence supporting the effectiveness of vitamin supplementation on cognitive function in older adults with Alzheimer's disease (AD) is limited, and the reporting quality of existing research is often overlooked. Objectives: to a) evaluate the effectiveness of vitamin supplementation on cognitive function in older adults with AD; b) describe the characteristics of supplementation protocols; and c) assess the reporting quality of these interventions. Methods: a systematic search of seven databases was conducted for randomized controlled trials (RCTs) up to February 2026. Included studies involved vitamin supplementation for patients with AD and assessed cognitive outcomes. The risk of bias and reporting quality were evaluated. Results: seventeen RCTs (n = 2,478 participants) were included. While eight studies reported some cognitive improvements or stabilization with vitamin B3, D, E, folic acid or specialized multi-nutrient formulations, nine found no significant benefit. A high risk of bias was identified in seven studies, while only five were rated as low risk. The median TIDieR score of 10/12 indicates a good description of the vitamin supplementation protocols. Conclusions: the current evidence for vitamin supplementation in older adults with AD is inconclusive. While some protocols show potential for stabilizing or improving cognitive domains, results are compromised by methodological heterogeneity and a high risk of bias. Future research must focus on enhancing methodological quality and achieving greater homogeneity in vitamin supplementation prescription and dosing to ensure robust clinical evidence for patients with AD.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"999-1012"},"PeriodicalIF":1.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147513633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of cardiovascular health with lung function and mortality in US adults: a national cohort study.","authors":"Yusheng Li, Jiemei Tang","doi":"10.20960/nh.06216","DOIUrl":"10.20960/nh.06216","url":null,"abstract":"<p><strong>Introduction: </strong>Background: cardiovascular health (CVH), as defined by the \"Life's Essential 8\" (LE8) metric, is crucial for overall well-being. However, the associations among CVH, lung function, and all-cause mortality remain insufficiently explored. This study aimed to examine these relationships and assess the mediating role of lung function. Methods: data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007-2012 cycles, with mortality follow-up through December 31, 2019. The LE8 score, comprising eight key components, was used to evaluate CVH. Lung function was assessed via forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and the FEV1/FVC ratio. Multiple regression analyses and mediation models were employed to explore associations and potential mediation effects. Results: among 10,819 adults, higher CVH was linked to enhanced lung function and lower all-cause mortality. Each one-point increment in the LE8 score corresponded to a 4 % reduction in mortality risk (hazard ratio [HR] = 0.96, 95 % confidence interval [CI] = 0.94-0.98, p < 0.001). Additionally, an increase of one LE8 point was associated with a 5.11 mL rise in FEV1 (β = 5.11, 95 % CI = 4.37-5.85, p < 0.001). Notably, the FEV1/FVC ratio mediated 18.03 % of the relationship between LE8 and mortality. Conclusions: better CVH, as assessed by LE8, correlates with superior lung function and reduced mortality risk. Furthermore, lung function, particularly the FEV1/FVC ratio, partially mediates this association. These findings underscore the interdependence of cardiovascular and respiratory health in shaping long-term survival outcomes.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"1064-1073"},"PeriodicalIF":1.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145636813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The modifiable effect of the Triglyceride-Glucose (TyG) index and the Dietary Index of Gut Microbiota (DI-GM) on the associations between conventional risk factors and stroke.","authors":"Songling Zhong, Yingjie Chen, Yuanxu Wang, Jiaxi Hu, Jing Yu, Yufeng Tang","doi":"10.20960/nh.06217","DOIUrl":"10.20960/nh.06217","url":null,"abstract":"<p><strong>Introduction: </strong>Background: stroke remains a leading cause of global mortality and disability. Beyond established risk factors, modifiable dietary and metabolic pathways, particularly those involving gut microbiota, offer promising targets for prevention. The Dietary Index of Gut Microbiota (DI-GM) quantitatively assesses diets that support a beneficial gut ecosystem, providing a novel tool for clinical nutrition practice. Objectives: this study examined the associations of the Triglyceride-Glucose Index (TyG) and Dietary Index of Gut Microbiota (DI-GM) with stroke risk, with a focus on their interactions with conventional risk factors and implications for nutritional interventions. Methods: We conducted a cross-sectional analysis of 15,456 U.S. adults from NHANES (2007-2020). Multivariable logistic regression with propensity score weighting was used to examine associations. Results: A nonlinear relationship was observed between the TyG index and stroke risk. Conversely, a DI-GM score ≥ 7 was significantly associated with a 20.5 % lower stroke risk. This protective effect was driven specifically by the beneficial dietary components within the DI-GM, which were linked to a 13 % risk reduction per unit increase, independent of traditional cardiovascular risk factors. Subgroup analyses revealed that the TyG index's association with stroke risk was potentiated in individuals with hypertension or diabetes. Conclusions: both the TyG index and the DI-GM are significant and complementary predictors of stroke risk. The DI-GM provides a validated nutritional framework for stroke prevention, advocating for a diet rich in fiber, fermented foods, and plant-based polyphenols. These findings underscore the potential of integrating metabolic and gut-microbiota focused dietary strategies, such as those captured by the DI-GM, into personalized clinical nutrition plans for high-risk individuals.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"1046-1057"},"PeriodicalIF":1.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147513728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of large language models in answering public questions about nutrition in cirrhosis: a comparative study.","authors":"Junzhen Li, Yingjie Wu, Man Yang, Lihua Ren, Jian Qi, Hui Ouyang","doi":"10.20960/nh.06997","DOIUrl":"https://doi.org/10.20960/nh.06997","url":null,"abstract":"<p><strong>Background: </strong>large language models (LLMs) are increasingly used for public health information, but their performance in nutrition advice for cirrhosis remains uncertain. We investigated four LLMs in answering public questions about cirrhosis nutrition across safety, accuracy, empathy, information reliability and quality, and readability.</p><p><strong>Methods: </strong>in this cross-sectional comparative study, 50 public facing questions about nutrition in cirrhosis were submitted once to each of four LLMs (ChatGPT 5.5, Claude Opus 4.7, DeepSeek V4 Pro, and Gemini 3.1 Pro Thinking) between May 10 and May 16, 2026. Three raters independently assessed 200 responses for safety, accuracy, empathy, and information quality. Readability was assessed with six indices.</p><p><strong>Results: </strong>a total of 200 responses were evaluated. Safety coding showed high inter-rater agreement (Fleiss' kappa = 0.864; 95 % CI, 0.755-0.958). ICC values for other manually scored outcomes ranged from 0.860 to 0.892. Potentially unsafe responses occurred in all models, ranging from 6.0 % to 12.0 %, with no significant difference across models (raw p = 0.599). Accuracy differed significantly across models (raw p = 0.003), with the highest median score for ChatGPT 5.5. Empathy also differed significantly (raw p < 0.001), with higher median scores for Claude Opus 4.7 and Gemini 3.1 Pro Thinking. DISCERN, EQIP, JAMA and all readability indices differed significantly across models, while GQS did not.</p><p><strong>Conclusion: </strong>current LLMs can provide useful general information about nutrition in cirrhosis, but none performed consistently well across safety, transparency, and readability. Their responses should supplement, not replace, guidance from hepatology and nutrition professionals.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Emotional factors and eating styles as predictors of binge eating disorder symptoms in women with overweight or obesity, considering age and nutritional status].","authors":"Neli Escandón Nagel, Antonia Fredericksen, Carlos Baeza Henríquez, Lea Vallejos-Barrera","doi":"10.20960/nh.06186","DOIUrl":"https://doi.org/10.20960/nh.06186","url":null,"abstract":"<p><strong>Introduction: </strong>binge eating disorder (BED) is the most common eating disorder and is linked to overweight/obesity, negative affect, and dysregulated eating patterns.</p><p><strong>Objective: </strong>to examine the impact of negative affect, emotional eating, and external eating on BED symptomatology in women with overweight or obesity, taking into account life stage and nutritional status.</p><p><strong>Materials and methods: </strong>participants were 313 Chilean women aged 18-61 years, with a BMI ≥ 25 and at least two binge episodes in the past month. The DEBQ (emotional and external subscales), BEDS-7, and PANAS (negative affect) were administered. MANOVA/ANOVA, mediation, and multiple regression analyses were performed, controlling for age and BMI.</p><p><strong>Results: </strong>MANOVA showed a significant effect of nutritional status on the set of dependent variables (negative affect, emotional eating, external eating, and BED symptomatology). ANOVA indicated that emotional eating was higher among women with obesity compared to those with overweight, with no differences by life stage and no interaction effects. Mediation analysis revealed that the association between negative affect and BED symptomatology was partially mediated, and only through emotional eating. Multiple regression accounted for 21.2 % of the variance in BED symptomatology, with negative affect and emotional eating as significant predictors. Age was inversely associated with BED symptomatology.</p><p><strong>Conclusions: </strong>negative affect and emotional eating play a key role in BED symptomatology. Emotional regulation should be prioritized in prevention and treatment efforts, with particular attention to younger women.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of chronic diseases and associated medications on thiamine metabolism in the non-demented elderly.","authors":"Pengyue Du, Zijie Wang, Ting Qian, Xiaoqin Cheng, Guoqiang Fei, Bingqiao Zhao, Xiaoli Pan, Shaoming Sang","doi":"10.20960/nh.06369","DOIUrl":"https://doi.org/10.20960/nh.06369","url":null,"abstract":"<p><strong>Objective: </strong>to evaluate the interplay among chronic diseases, pharmacotherapy, and apolipoprotein E (APOE) genotype on thiamine homeostasis in non-demented elderly individuals.</p><p><strong>Methods: </strong>in this community-based cross-sectional study, we recruited 1322 cognitively normal elderly (578 males, 744 females) aged over 60 years from Xuhui District, Shanghai. Demographic characteristics of disease and medication history were collected by questionnaires. Cognitive function was evaluated using the Mini-Mental State Examination (MMSE). APOE genotyping was identified using single nucleotide polymorphism analysis. Thiamine diphosphate (TDP), thiamine monophosphate (TMP), and free thiamine (FT) were measured by high-performance liquid chromatography (HPLC).</p><p><strong>Results: </strong>a total of 281 APOE ε4 carriers and 1041 non-carriers were enrolled in this study. All of participants had an average educational background of over 9 years and a MMSE score of 27.90 ± 2.35. Disease subgroups were classified as follows: hypertension (37.5 %, n = 496), diabetes (5.75 %, n = 76), hypertension with diabetes (8.02 %, n = 106), cardiovascular disease (4.31 %, n = 57), and multimorbidity subgroups. There were no significant differences in TDP levels between healthy controls and all of the disease subgroups in non-demented elderly. Furthermore, the pharmacotherapy also showed no significant effects on TDP levels under those disease condition. Additionally, both APOE ε4 carriers and non-carriers within each of the disease subgroups exerted comparable TDP levels.</p><p><strong>Conclusion: </strong>our results indicated that common chronic diseases and their standard pharmacotherapy do not significantly alter thiamine metabolism in non-demented elderly. The APOE ε4 genotype shows no modifying effect on thiamine homeostasis in this population, regardless of the presence or absence of disease comorbidity.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Inter-phase hyponatremia ‒ A case report of a three-phase response in antidiuretic hormone release following pituitary surgery].","authors":"María Villaescusa Lage, Jordi Ferri Ciscar, Maitane Hernando Llorens, Alicia Pérez Fuster, Natalia Gutiérrez Mora, María B Toledo Juan, Javier Marín Santonja, María Hermenegildo Zamora, Daniel Polanco Fajardo, Ning Yung Wu Xiong, José T Real Collado","doi":"10.20960/nh.07108","DOIUrl":"10.20960/nh.07108","url":null,"abstract":"<p><strong>Introduction: </strong>Introduction: electrolyte disorders are the most common complication following pituitary surgery, with hyponatremia occurring in up to 25 % of cases. The triphasic response of antidiuretic hormone is a rare entity characterized by a sequence of transient vasopressin deficiency secondary to damage of the neurohypophyseal axonal tracts, followed by a phase of syndrome of inappropriate antidiuretic hormone secretion (SIADH) due to the release of preformed vasopressin, and finally by permanent vasopressin deficiency secondary to neuronal gliosis. Case report: we present the case of a 34-year-old woman who underwent pituitary adenoma resection and subsequently developed this complication. Discussion: this case highlights the importance of close postoperative monitoring and early treatment to prevent potentially serious complications.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"44-47"},"PeriodicalIF":1.3,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}