{"title":"[Alcohol and tobacco: synergistic factors in breast cancer - A reflection based on scientific evidence].","authors":"Raúl Aguilera-Eguía, Héctor Fuentes-Barria, Cherie Flores-Fernández, Ángel Roco-Videla, Víctor Pérez-Galdavini, Olga Patricia López-Soto","doi":"10.20960/nh.05755","DOIUrl":"10.20960/nh.05755","url":null,"abstract":"<p><strong>Introduction: </strong></p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"614-615"},"PeriodicalIF":2.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Walter Sepúlveda-Loyola, Yshoner Antonio Silva-Díaz, Mário Molari, Erikson Alexander Jiménez Torres, Cintya Odar-Rojas, Denilson Teixeira, Vanessa Probst
{"title":"Association between the fat mass/fat-free mass ratio and muscle strength, static balance and exercise capacity in older adults: a cross-sectional study.","authors":"Walter Sepúlveda-Loyola, Yshoner Antonio Silva-Díaz, Mário Molari, Erikson Alexander Jiménez Torres, Cintya Odar-Rojas, Denilson Teixeira, Vanessa Probst","doi":"10.20960/nh.05616","DOIUrl":"10.20960/nh.05616","url":null,"abstract":"<p><strong>Introduction: </strong>Background: the FM/FFM ratio has been proposed as a new body composition variable. However, the association between FM/FFM ratio and physical function in older adults remains limited. Therefore, the aim of this study was to analyze the association between FM/FFM ratio and muscle strength, static balance, and exercise capacity in older adults. Methods: this was a cross-sectional study involving 392 older adults from Londrina, Brazil. Subjects underwent body composition analysis by bioelectrical impedance, and assessments for aerobic capacity, muscle strength and static balance including the 6-minutes walking test, handgrip strength and one-legged stance test. Statistical analysis was conducted using correlation tests and lineal regression models adjusted for age and gender. The statistical significance considered was p < 0.05. Results: a total of 392 older adults participated (mean age = 69.77 years; women: 74.7 %). The FM/FFM ratio was significantly associated with muscle strength (β = -22.779, 95 % CI: -26.741 to -18.818; p < 0.001), static balance (β = -14.335, 95 % CI: -19.980 to -8.690; p < 0.001), and exercise capacity (β =-98.937, 95 % CI: -152.286 to -45.588, p < 0.001). After adjusting for age and gender, FM/FFM ratio was an important predictor of muscle strength (β = -4.687, 95 % CI: -8.646 to -0.728; p = 0.020) and static balance (β = -18.361, 95 % CI: -24.943 to -11.778; p < 0.001). Conclusions: the FM/FFM ratio is an important clinical measure of body composition that is significantly associated with key indicators of physical performance, including muscle strength, static balance, and exercise capacity in older adults.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":"464-469"},"PeriodicalIF":2.5,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gladys Ruth Morales Illanes, Claudia Bugueño, Rodrigo Valenzuela, Rodrigo Chamorro, Carla Leiva, Martin Gotteland, Silvana Trunce-Morales, Nicolás Pizarro-Aranguiz, Samuel Durán-Agüero
{"title":"[Dairy consumption in Chile: comparison by gender, age, geographic area and socioeconomic level, and barriers associated to intake].","authors":"Gladys Ruth Morales Illanes, Claudia Bugueño, Rodrigo Valenzuela, Rodrigo Chamorro, Carla Leiva, Martin Gotteland, Silvana Trunce-Morales, Nicolás Pizarro-Aranguiz, Samuel Durán-Agüero","doi":"10.20960/nh.05594","DOIUrl":"https://doi.org/10.20960/nh.05594","url":null,"abstract":"<p><strong>Objective: </strong>the main objective was to characterize dairy consumption by gender, age, geographic area, and socioeconomic status (SES). Additionally, the following secondary objectives were established: a) to identify the main barriers to dairy consumption, b) to compare intake with Chilean dietary guidelines, and c) to analyze the consumption of dairy beverages among older adults Methods: cross-sectional study. An on-line questionnaire was applied at national level, previously validated according to the content validity index. This survey included type and frequency of dairy consumption and main consumption barriers. In addition, sociodemographic and lifestyle background.</p><p><strong>Results: </strong>a total of 2008 people participated in the study, the average age was 39.4 ± 15.8 years and 55.5 % were female. Likewise, 46.9 %, 53.7 % and 87 % belonged to the group < 35 years, central zone, and low/middle SES, respectively. The most consumed dairy products were: cheese (83.3 %), milk (76.2 %) and yogurt (73.7 %); 23.7 % of the sample reached the consumption recommendations. Women presented higher consumption of milk, yogurt, cheese, goat milk, lactose-free milk, homemade yogurt and kefir (p < 0.05), while men reported higher consumption of cheese and milk-based desserts (p < 0.05). Older people and people with a low SES presented the lowest prevalence of consumption compliance. The main barriers for not consuming dairy products were: having lactose intolerance, unpleasant taste, considering them harmful to health and preferring to obtain nutrients from other foods. Consumption of dairy beverages in older people reached 37 %.</p><p><strong>Conclusion: </strong>cheese was the most consumed dairy product, followed by milk and yogurt, with consumption differences observed based on gender, age, geographic area, and SES. There was low adherence to the dairy consumption recommendations established in the Chilean dietary guidelines. Lactose intolerance was identified as the main barrier to consumption. Additionally, it was reported that approximately one-third of the older population consumes dairy beverages.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between community environment and metabolic sydrome among Chinese middle-aged and older adults - Evidence from the national longitudinal surveys from 2011 to 2015.","authors":"Xiangyu Tang, Feifei Yao, Fengyan Li, Liqin Xiao, Xiaoming Liu, Fen Liu, Jian Yang, Shujia Xu, Zhiling Liu, Fulan Hu, Xiuyun Chen","doi":"10.20960/nh.05474","DOIUrl":"https://doi.org/10.20960/nh.05474","url":null,"abstract":"<p><strong>Background: </strong>community environments that encourage active and socially engaged lifestyles may help reduce the risk of metabolic syndrome (MetS). This study aims to examine the relationship between community cultural and recreational environments and the incidence of MetS among middle-aged and older Chinese individuals.</p><p><strong>Methods: </strong>we used data from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2015, we included participants aged 45 years and older with complete relevant data. Community environments were classified into three categories using hierarchical clustering analysis. Multivariate logistic regression models were employed to examine associations between community environments and MetS.</p><p><strong>Findings: </strong>among 6,321 participants, 1,403 developed MetS during the follow-up period. Those who developed MetS were older, less educated, currently drinking, engaged in agricultural work, and lived in northern or rural areas, primarily in Category 1 communities. Participants in Category 2 (OR: 0.69, 95 % CI: 0.55-0.87) and Category 3 (OR: 0.57, 95 % CI: 0.33-0.93) communities had a lower risk of MetS compared to those in Category 1. Significant associations were found among middle-aged individuals and males in Category 2, and among females in both Category 2 and Category 3 communities.</p><p><strong>Conclusion: </strong>our findings suggest that community environments with robust cultural, sports, and recreational support are associated with a lower risk of MetS among middle-aged and older adults in China. These findings emphasize the importance of well-rounded community environments in promoting metabolic health.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Individualised nutritional intervention and care in patients with type 2 diabetes mellitus combined with a heart attack.","authors":"Ronghong Liu, Yan Hong, Jichang Kong","doi":"10.20960/nh.05209","DOIUrl":"https://doi.org/10.20960/nh.05209","url":null,"abstract":"<p><strong>Introduction: </strong>diet and nutrition interventions may prove more effective than drug interventions in reducing hyperglycaemia in patients with type 2 diabetes mellitus (DM). However, as individual responses to nutritional strategies can vary, it is crucial to develop tailored nutritional interventions to effectively manage hyperglycaemia.</p><p><strong>Objective: </strong>to assess the effectiveness of individualised nutritional intervention and care in patients diagnosed with type 2 DM and concurrent heart attack.</p><p><strong>Methods: </strong>this randomised controlled trial involved participants diagnosed with both type 2 DM and a recent heart attack. The intervention group received customised nutritional counselling and dietary plans adapted to their medical conditions, whereas the control group adhered to regular dietary recommendations. Baseline measures, including blood glucose levels, lipid profiles, and cardiac markers, were recorded and analysed between the groups.</p><p><strong>Results: </strong>substantial improvements were observed in the health parameters of the intervention group. Notably, there were reductions in postprandial blood glucose levels, enhancements in lipid profiles, and more favourable cardiac marker profiles compared with those in the control group. The results also underscored the practicality and effectiveness of personalised nutritional interventions in clinical settings.</p><p><strong>Conclusions: </strong>individualised nutritional intervention and care positively impacted the health outcomes of patients with type 2 DM and a recent heart attack, highlighting the value of personalised care approaches.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship between adherence to the Mediterranean diet, quality of life, anthropometric measurements, and some biochemical parameters in patients with coronary artery disease.","authors":"Canan Tekin, Hasan Tut, Ayhan Dağ","doi":"10.20960/nh.05857","DOIUrl":"https://doi.org/10.20960/nh.05857","url":null,"abstract":"<p><strong>Objective: </strong>this study aimed to evaluate the relationship between adherence to the Mediterranean diet, quality of life, anthropometric measurements, and biochemical parameters in patients with coronary artery disease (CAD).</p><p><strong>Methods: </strong>a total of 316 adults (≥ 19-91 years-old), 139 (44 %) female and 177 (56 %) male, participated in the study. Three groups were created: the group with normal coronary arteries, the low-medium risk group with 1-69 % stenosis in coronary arteries, and the high-risk group with ≥ 70 % stenosis. In the study, anthropometric and some biochemical parameters were examined. The \"Mediterranean Diet Adherence Screener (MEDAS)\" and the \"Quality of Life Questionnaire (SF-36)\" were used.</p><p><strong>Results: </strong>the maximum mean age of the participants was 61.72 ± 11.03 years in the high CAD risk group, the prevalence of obesity was 58.6% in the low-medium CAD risk group. In the group with normal arteries, MEDAS (p1 < 0.05, p2 < 0.05) and SF-36 scores (physical function, pain, vitality sub-dimensions) were found to be higher (p1 < 0.05). A significant correlation was found between MEDAS and total cholesterol (r = -0.235, p = 0.013), LDL cholesterol (r = 0.212, p = 0.025), social function (r = -0.273, p = 0.006), general health (r = -0.223, p = 0.023), and mental health (r = -0.120, p = 0.033) parameters, but not with other parameters (p > 0.05).</p><p><strong>Conclusions: </strong>disseminating Mediterranean diet as a health policy may be effective in both reducing CAD risk and improving quality of life.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cecilia Arteaga-Pazmiño, Javier Javier Gálvez-Celi, Melisa Sánchez, Noemi Georgina Díaz Menéses, Doménica Salcedo Martínez, Belén Castillo Álava, María Quintana Rodríguez, Samuel Durán-Agüero
{"title":"[Food consumption in the context of an energy crisis: the case of Ecuador].","authors":"Cecilia Arteaga-Pazmiño, Javier Javier Gálvez-Celi, Melisa Sánchez, Noemi Georgina Díaz Menéses, Doménica Salcedo Martínez, Belén Castillo Álava, María Quintana Rodríguez, Samuel Durán-Agüero","doi":"10.20960/nh.05834","DOIUrl":"https://doi.org/10.20960/nh.05834","url":null,"abstract":"<p><strong>Background: </strong>food consumption can be affected during energy crises.</p><p><strong>Objective: </strong>to characterize the food consumption of the Ecuadorian population during the period of electric rationing.</p><p><strong>Methods: </strong>observational and retrospective study. The population consisted of Ecuadorian adults aged 18 and older who resided in cantons of the country during the 2024 electric rationing period. Food consumption was assessed through an online survey validated by experts, with 23 questions about the frequency of food consumption and changes in purchasing and consumption habits by food groups.</p><p><strong>Results: </strong>a total of 550 subjects participated, mainly from urban areas (86.5 %). Of these, 62.2 % were male, and 78.5 % of respondents were aged between 18 and 39 years. 53.3 % reported a reduction in grocery purchases, while 27.8 % increased their purchase of prepared meals. Regarding food groups, 30.9 % consumed vegetables once a day, 24.7 % consumed fruits 2 to 4 times a week, and 33.8 % consumed legumes 2 to 4 times a week. For cereals and tubers, 29.6 % consumed them once a day; 30 % reported consuming fats once a day, and 20.4 % consumed ultra-processed foods once a week; 46.5 % increased food waste, and 76 % changed their consumption of refrigerated products.</p><p><strong>Conclusions: </strong>electric rationing impacted the food consumption of Ecuadorians, especially in dairy, vegetables, and food waste.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Mindfulness as an emerging strategy against obesity in children and adults].","authors":"Ángel Roco-Videla, Raúl Aguilera-Eguía, Mariela Olguín-Barraza, Sergio Flores","doi":"10.20960/nh.05905","DOIUrl":"https://doi.org/10.20960/nh.05905","url":null,"abstract":"","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristian Gabriel Álvarez Lepin, Paulina Ibacache-Saavedra, Carolina Fuentes, Macarena Ramos, Claudia Marchant, Lorena Martinez-Ulloa, Lissé Chiquinquirá Angarita-Dávila, Igor Cigarroa, David Andrade, Felipe Caamaño-Navarrete, Guido Contreras-Díaz, Luis Javier Chirosa-Ríos, Pedro Delgado-Floody
{"title":"Skeletal muscle and body fat interact with blood pressure in cerebral vascular disease: characterization study from the Chilean National Health Survey 2016-17.","authors":"Cristian Gabriel Álvarez Lepin, Paulina Ibacache-Saavedra, Carolina Fuentes, Macarena Ramos, Claudia Marchant, Lorena Martinez-Ulloa, Lissé Chiquinquirá Angarita-Dávila, Igor Cigarroa, David Andrade, Felipe Caamaño-Navarrete, Guido Contreras-Díaz, Luis Javier Chirosa-Ríos, Pedro Delgado-Floody","doi":"10.20960/nh.05721","DOIUrl":"https://doi.org/10.20960/nh.05721","url":null,"abstract":"<p><strong>Background: </strong>peripheral (PVD) and cerebral vascular disease (CeVD) are two vascular conditions of relevance in older adults. However, there is little epidemiological studies about the body composition role (i.e., skeletal muscle mass [by calf circumference] and adiposity [by waist circumference]) in the diabetes and hypertension (HTN) prevalence in PVD and CeVD conditions.</p><p><strong>Aim: </strong>to describe the characteristics of population with PVD and CeVD by different body composition phenotypes and determine the interaction between PVD/CeVD, and body composition with the HTN and diabetes prevalence.</p><p><strong>Methods: </strong>a cross-sectional study of the Chilean population based on the National Health Survey 2016-17. A sample size of n = 233 participants was characterized according to previous PVD and CeVD or not No-PVD/No-CeVD history. Four body composition phenotypes were described such as; low skeletal muscle mass plus high waist circumference (Lsmm-Hwc), low skeletal muscle mass plus low waist circumference (Lsmm-Lwc), high skeletal muscle mass plus high waist circumference (Hsmm-Hwc), and high skeletal muscle mass plus low waist circumference (Hsmm-Lwc), by main outcomes as systolic (SBP), and diastolic BP (DBP) and fasting glucose.</p><p><strong>Results: </strong>there was a significant interaction between body composition (Groups x CeVD), in SBP (CeVD, F (3.40), p = 0.002, ES: 0.007), where SBP in Lsmm-Lwc was higher (diff +28 mmHg) versus the Hsmm-Lwc reference group. Lsmm-Hwc (odds ratio [OR], 3.2 [1.8; 5.9], p < 0.0001), Lsmm-Lwc (OR, 1.7 [1.0; 3.1], p = 0.047), and Hsmm-Hwc (OR, 2.2 [1.5; 3.3], p < 0.0001) showed a higher risk for suffering from PVD vs. Hsmm-Lwc group.</p><p><strong>Conclusion: </strong>Chilean adults with both PVD and CeVD are shown to be aged 60, with obesity and hypertensive condition, and report lower handgrip strength in comparison with adult peers with higher muscle mass and lower waist circumference.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of socioeconomic status and nine modifiable lifestyle factors on esophageal cancer risk in European and East Asian populations - Evidence from a comprehensive Mendelian randomization study.","authors":"Ruizhi Ye, Fengming Zhang, Guangxian You","doi":"10.20960/nh.05819","DOIUrl":"https://doi.org/10.20960/nh.05819","url":null,"abstract":"<p><strong>Background and aims: </strong>the intricate relationships between socioeconomic factors, modifiable lifestyle choices, and esophageal cancer risk remain uncertain. We aim to investigate the associations of socioeconomic status, modifiable lifestyle factors, and esophageal cancer risk.</p><p><strong>Methods: </strong>we employed multiple Mendelian randomization (MR) analyses, including three different MR approaches. GWAS databases from European and East Asian populations, encompassing variables such as household income, educational attainment, and the Townsend deprivation index (TDI), were analyzed. The risk of esophageal cancer was assessed using data from three distinct cohorts of European and East Asian descent (Database 1: n = 476,306; Database 2: n = 372,756; Database 3: n = 160,589). Nine modifiable lifestyle factors were incorporated in the multivariable and mediation MR analyses. Meta-analysis was employed to synthesize results across the three datasets.</p><p><strong>Results: </strong>higher household income was connected with a reduced esophageal cancer risk (odds ratio (OR) = 0.698, 95 % confidence interval (95 % CI): 0.556-0.876, p = 0.002). Body mass index (BMI) partially mediated the relationship between household income and the risk of esophageal cancer (OR = 0.914, 95 % CI: 0.841-0.992, p = 0.031, mediation ratio: 27.23 %). However, no significant evidence was found to support a direct association between educational attainment, TDI, and esophageal cancer risk.</p><p><strong>Conclusions: </strong>these findings suggest that higher household income is inversely associated with esophageal cancer risk, with BMI acting as a partial mediator of this relationship. Accordingly, targeted early screening and preventive measures for esophageal cancer should be prioritized among low-income populations, particularly those with obesity.</p>","PeriodicalId":19385,"journal":{"name":"Nutricion hospitalaria","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}