Nutrition in Clinical Practice最新文献_第3页

YouTube as a possible learning platform for patients and their family caregivers for gastrostomy tube feeding: A cross-sectional study. 将YouTube作为胃造瘘管喂养患者及其家庭护理人员的学习平台：横断面研究。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-04-01 Epub Date: 2024-07-03 DOI: 10.1002/ncp.11186

Hyeon Sik Chu, Hanyi Lee

{"title":"YouTube as a possible learning platform for patients and their family caregivers for gastrostomy tube feeding: A cross-sectional study.","authors":"Hyeon Sik Chu, Hanyi Lee","doi":"10.1002/ncp.11186","DOIUrl":"10.1002/ncp.11186","url":null,"abstract":"Background: Many patients and family caregivers have informational needs, especially regarding gastrostomy care and home gastrostomy tube feeding. YouTube is a potential accessible option for educational resources concerning these topics.Methods: This study aimed to explore the educational quality and content of informational YouTube videos. We used \"gastrostomy,\" \"G-tube,\" \"enteral feeding,\" and \"enteral nutrition,\" as search keywords on YouTube on October 3, 2021. A total of 229 videos were evaluated using the global quality scale (GQS) and modified DISCERN scoring system. Variables extracted from the videos included general features, video parameters, and content themes.Results: The GQS and modified DISCERN scores were 3.31 ± 0.90 and 2.63 ± 1.23, respectively. There were educational quality and differences among videos uploaded by various agencies. Frequent video content themes included \"cleaning and dressing a gastrostomy tube,\" \"bolus method,\" and \"replacing a balloon-type of gastrostomy tube.\"Conclusion: Results showed that YouTube can be a supplemental educational resource for people requiring gastrostomy care and for their caregivers. However, given the open-access nature of YouTube, healthcare professionals' guidance is needed for video selection. Healthcare professionals should know and use specific, reliable resources to effectively guide and educate patients with gastrostomy and their caregivers, enhancing their self-management skills and knowledge.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":"389-396"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A prospective cross-sectional-comparative analysis of nutrition screening and assessment tools in chinese nasopharyngeal carcinoma inpatients undergoing radiotherapy using Global Leadership Initiative on Malnutrition criteria as the gold standard. 以全球营养不良领导倡议标准为金标准，对中国鼻咽癌放疗住院患者营养筛查和评估工具进行前瞻性横断面比较分析。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-03-20 DOI: 10.1002/ncp.11282

Ruizhen Wu, Shu Tian, Haodong Wang, Qin Shi, Jianhong Ma

{"title":"A prospective cross-sectional-comparative analysis of nutrition screening and assessment tools in chinese nasopharyngeal carcinoma inpatients undergoing radiotherapy using Global Leadership Initiative on Malnutrition criteria as the gold standard.","authors":"Ruizhen Wu, Shu Tian, Haodong Wang, Qin Shi, Jianhong Ma","doi":"10.1002/ncp.11282","DOIUrl":"https://doi.org/10.1002/ncp.11282","url":null,"abstract":"Objectives: The aim was to assess the diagnostic accuracy of four different nutrition screening and evaluation instruments in nasopharyngeal carcinoma patients, benchmarked against Global Leadership Initiative on Malnutrition (GLIM) criteria.Methods and study design: An observational, single-institution study was conducted between June 2022 and May 2023. Nutrition status was assessed using Nutritional Risk Screening 2002 (NRS-2002), Malnutrition Universal Screening Tool (MUST), Malnutrition Screening Tool (MST), Patient-Generated Subjective Global Assessment (PG-SGA), and GLIM criteria at two time points: postadmission and predischarge. Metrics such as sensitivity, specificity, concordance, and Kappa coefficient were computed.Results: For the trial, 140 participants were enrolled. Based on GLIM criteria, the rate of undernutrition was 22.9% before radiation and 73.6% after it ended. NRS-2002 (k = 0.721) demonstrated substantial concordance with GLIM criteria at admission, followed by MUST (k = 0.604) and MST (k = 0.378). Kappa coefficients were reduced at discharge (NRS-2002: k = 0.696; MUST: k = 0.690; MST: k = 0.496). GLIM criteria were moderately consistent with PG-SGA at admission (k = 0.453) and slightly consistent at discharge (k = 0.136).Conclusions: NRS-2002 demonstrated greater concordance with GLIM criteria than MUST and MST. Therefore, NRS-2002 could be a more appropriate choice for initial nutrition screening in the diagnostic framework of GLIM for individuals afflicted with nasopharyngeal cancer, both before and after radiotherapy. The alignment of GLIM criteria with PG-SGA in identifying undernourished patients varied from slight to moderate.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutrition management of a patient following emergent pneumonectomy due to chest wall trauma. 一例胸壁创伤急诊全肺切除术后患者的营养管理。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-03-18 DOI: 10.1002/ncp.11291

Stacy Pelekhaty, Rebecca Brody

{"title":"Nutrition management of a patient following emergent pneumonectomy due to chest wall trauma.","authors":"Stacy Pelekhaty, Rebecca Brody","doi":"10.1002/ncp.11291","DOIUrl":"https://doi.org/10.1002/ncp.11291","url":null,"abstract":"Emergent total pneumonectomy is a rare surgical intervention for patients with severe chest trauma. Patients who survive the immediate postoperative period experience prolonged, complex hospitalizations. The purpose of this case study is to review the nutrition care provided to a patient who survived total pneumonectomy and the supporting evidence. John Doe (JD) is a man aged 28 years who presented to a level I trauma center with penetrating chest trauma. He required multiple operative interventions, resulting in a partial right and total left pneumonectomy. JD's hospitalization was complicated by prolonged use of extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT). His surgical course and gastric feeding intolerance hampered enteral nutrition adequacy, and parenteral nutrition support was initiated on hospital day 17. Tolerance to enteral nutrition improved after jejunal access was obtained, and the patient transitioned to total enteral nutrition support. As a result of inflammatory metabolic changes and nutrition delivery challenges for the first 2 weeks of hospitalization, JD developed malnutrition. His nutrition care was further complicated by copper and carnitine deficiencies, which have been described in patients requiring ECMO and CRRT. Patients who require emergent total pneumonectomy following traumatic chest injuries will likely require complex hospital care, including extracorporeal organ support. These patients present unique nutrition challenges; however, given the relative infrequency of the intervention, there is limited research to guide clinical practice. Additional research on nutrition interventions in this population is warranted.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A prospective observational study of decision-making by patients with amyotrophic lateral sclerosis upon recommendation for PEG enteral feeding tubes. 一项前瞻性观察研究，旨在了解肌萎缩性脊髓侧索硬化症患者在被推荐使用 PEG 肠内喂养管时的决策情况。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-03-18 DOI: 10.1002/ncp.11290

Kay Tran, Heather A Hayes, Mark Bromberg

{"title":"A prospective observational study of decision-making by patients with amyotrophic lateral sclerosis upon recommendation for PEG enteral feeding tubes.","authors":"Kay Tran, Heather A Hayes, Mark Bromberg","doi":"10.1002/ncp.11290","DOIUrl":"https://doi.org/10.1002/ncp.11290","url":null,"abstract":"Objective: To understand challenges surrounding acceptance of a percutaneous endoscopic gastroscopic enteral feeding tube by patients with amyotrophic lateral sclerosis: a prospective observational study.Methods: This was a prospective observational study of 41 patients and care partners attending a multidisciplinary Motor Neuron Disease clinic. Surveys were administered pregastrostomy tube placement (N = 23) and postplacement (N = 41). Some were not available both pre- and postplacement). For preplacement, we queried barriers affecting their decision for receiving a gastrostomy tube at the time of recommendation. For postplacement, we queried factors that influenced their decision as well as perceived benefit and satisfaction with use.Results: Patient concerns about receiving a gastrostomy tube centered on the procedure, possible pain/infection (48%), limitations on activities (44%), impact on body image, and possible extension of life. For patients who received a gastrostomy tube, satisfaction was very high (93%), and there was reduced patient (59%) and care partners (54%) stress. The average BMI was 28.6 kg/m2 at diagnosis, and there was no net gain in weight. The average time until placement of a gastrostomy tube following recommendation was 145 days (range 13-824 days).Conclusions: Despite counseling at multiple time points, the decision to obtain a feeding tube is often challenging for patients and care partners. Gastrostomy tube placement was perceived as a substantial benefit. Addressing these barriers may reduce concerns and promote earlier decision-making to maximize the benefits of placing a gastrostomy tube sooner.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic intestinal failure knowledge among a cohort of ASPEN registered dietitians: Response to a membership survey. 一组ASPEN注册营养师的慢性肠衰竭知识：对会员调查的回应。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-03-11 DOI: 10.1002/ncp.11287

Maryanna Tosi, Marion Winkler, Nicole Zubizaretta, Marjorie Nisenholtz, Michelle Spangenberg, Kelly Anne Tappenden, Kishore Iyer

{"title":"Chronic intestinal failure knowledge among a cohort of ASPEN registered dietitians: Response to a membership survey.","authors":"Maryanna Tosi, Marion Winkler, Nicole Zubizaretta, Marjorie Nisenholtz, Michelle Spangenberg, Kelly Anne Tappenden, Kishore Iyer","doi":"10.1002/ncp.11287","DOIUrl":"https://doi.org/10.1002/ncp.11287","url":null,"abstract":"Background: Rare and nutritionally complex diseases, like chronic intestinal failure (CIF), are not encountered regularly by clinicians. Specialized centers with experience in intestinal failure are relatively sparse, leading many patients to rely on local clinicians. Previously published reports demonstrated lack of knowledge in intestinal failure among gastroenterologists in the United States, in Europe, and in the United Kingdom. This study aims to evaluate intestinal failure knowledge in a cohort of registered dietitians.Methods: A validated, 20-question survey on CIF knowledge covering four key domains was sent to dietitian members of the American Society for Parenteral and Enteral Nutrition. Descriptive data were collected regarding respondents' clinical practice characteristics. Performance was evaluated, and results were compared between self-identified experts and nonexperts in CIF and parenteral nutrition.Results: Of 94 respondents, 34% self-identified as experts in intestinal failure and 53% in parenteral nutrition management. Most self-identified intestinal failure experts (81.3%) reported managing 11-20 patients with CIF annually, but less than half worked with a multidisciplinary team, and less than one-quarter practiced in an intestinal rehabilitation program. Overall median score was 13.0 (IQR 11.0-15.0). Self-identified dietitians reporting expertise in intestinal failure and parenteral nutrition scored 15 (IQR 12-17) and 14 (IQR 12-17), respectively.Conclusion: Regardless of self-reported level of expertise, dietitian knowledge scores were high for home parenteral nutrition monitoring and complications of CIF. Given the integral role nutrition plays in intestinal failure, dietitians should be involved in the management of patients with CIF.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monitoring MUAC reflects the adequacy of nutrition support in critically ill children with a longer intensive care unit stay: A single-center prospective cohort study. 监测MUAC反映了重症监护时间较长的危重儿童营养支持的充分性：一项单中心前瞻性队列研究。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-03-10 DOI: 10.1002/ncp.11289

Yue Zhang, Zichen Fang, Xuelin Zhao, Xiaodong Zhu, Yueniu Zhu, Yi Feng

{"title":"Monitoring MUAC reflects the adequacy of nutrition support in critically ill children with a longer intensive care unit stay: A single-center prospective cohort study.","authors":"Yue Zhang, Zichen Fang, Xuelin Zhao, Xiaodong Zhu, Yueniu Zhu, Yi Feng","doi":"10.1002/ncp.11289","DOIUrl":"https://doi.org/10.1002/ncp.11289","url":null,"abstract":"Background: Children who are critically ill frequently experience inadequate nutrition, resulting in changes in body composition. We investigated the nutrition status and body composition changes among children with prolonged stays in the pediatric intensive care unit (PICU), utilizing midupper arm circumference (MUAC), and triceps skinfold thickness (TSF) measurements.Methods: A single-center prospective cohort study monitored nutrition support for children admitted to the PICU for over 6 days. MUAC and TSF were measured at admission and every other day through the 15th day of the PICU stay. Target energy was caculated using the Schofield formula without stress correction, and recommended protein intake was set at 1.5 g/(kg/d). Factors influencing changes in anthropometry were analyzed through pairwise correlation and regression analysis.Results: Sixty children with a median PICU stay of 9 days were included. MUAC decreased by 2.53% in the first week and by 7.42% over 2 weeks. During the first week, average energy and protein intakes were only 53.0% and 41.3% of recommended levels, respectively. Decreases in MUAC correlated with mean cumulative energy deficits (1 week: r = 0.310 [P = 0.016]; 2 weeks: r = 0.504 [P = 0.023]) and mean cumulative protein deficits (1 week: r = 0.304 [P = 0.018]).Conclusions: Many children with longer PICU stays did not met energy and protein recommendations. Decreases in MUAC were associated with deficits in energy and protein intake. Monitoring MUAC is a valuable tool for assessing nutrition support adequacy in children with longer PICU stays.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding how foods and enteral feedings influence the gut microbiome. 了解食物和肠内喂养如何影响肠道微生物群。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-03-06 DOI: 10.1002/ncp.11285

Gail A M Cresci

{"title":"Understanding how foods and enteral feedings influence the gut microbiome.","authors":"Gail A M Cresci","doi":"10.1002/ncp.11285","DOIUrl":"https://doi.org/10.1002/ncp.11285","url":null,"abstract":"The gut microbiome supports both gut and overall health. Diet is known to be one of the driving factors that influences the gut microbiome. The foods we eat, the dietary and nondietary components they contain, various food consumption patterns, and the ratio of nutrients consumed have been shown to impact gut microbiome composition and function. Studies indicate that many acute and chronic diseases are associated with alterations to the gut microbiome. There are many patients who rely on enteral tube feeding for their nutrition support. More recently, enteral tube feeding formulations of \"real food\" have become commercially available. However, little is known about how enteral tube feeding impacts the gut microbiome in patients requiring this specialized form of nutrition therapy. This review summarizes the existing evidence regarding the food sources of commonly consumed macronutrients and their impact on the gut microbiome. Also presented is what is known regarding \"standard\" and real food enteral formulations on the gut microbiome. Existing evidence is suggestive that real food enteral formulations positively impact the gut microbiome. Still, more research is needed on ready-to-feed formulations, particularly in patients with various clinical conditions, and how gut microbiome modulation impacts clinical outcomes.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SARC-F questionnaire and its predictive value for mortality risk in hospitalized younger adults: A retrospective study. SARC-F问卷及其对住院青年死亡风险的预测价值：一项回顾性研究。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-03-05 DOI: 10.1002/ncp.11284

Yuria Ishida, Keisuke Maeda, Akio Shimizu, Junko Ueshima, Ayano Nagano, Tatsuro Inoue, Tomoyuki Nonogaki, Koki Kawamura, Tatsuma Sakaguchi, Naoharu Mori

{"title":"SARC-F questionnaire and its predictive value for mortality risk in hospitalized younger adults: A retrospective study.","authors":"Yuria Ishida, Keisuke Maeda, Akio Shimizu, Junko Ueshima, Ayano Nagano, Tatsuro Inoue, Tomoyuki Nonogaki, Koki Kawamura, Tatsuma Sakaguchi, Naoharu Mori","doi":"10.1002/ncp.11284","DOIUrl":"https://doi.org/10.1002/ncp.11284","url":null,"abstract":"Background: Sarcopenia is a progressive loss of skeletal muscle mass and strength that can also occur in younger adults. The validity of the SARC-F questionnaire in younger populations has not been extensively investigated.Methods: A retrospective study was conducted using medical records of patients aged <65 years who were admitted to and discharged from a 900-bed university hospital between April 2019 and March 2021. The SARC-F score was documented upon admission. Associations between SARC-F scores and mortality were evaluated through receiver operating characteristic (ROC) curve analysis and Cox proportional hazards models.Results: A total of 12,743 patients were included (mean age, 47 [IQR 35-56] years; 56.3% women). During the observation period, mortality rates were 0.3%, 1.0%, 2.0%, and 3.3% for those aged 18-34, 34-46, 47-55, and 56-64 years, respectively. The ROC analysis showed that SARC-F scores at admission had a significant area under the ROC curve (0.721, IQR 0.678-0.764; P < 0.001) for predicting mortality. Using mortality during the observation period and in-hospital death as external criteria, the optimal SARC-F cutoff score was 1. Cox proportional hazards analysis revealed that a SARC-F score ≥1 was associated with significantly higher hazard ratios across all age groups (ranging from 3.77 to 9.47; all P < 0.01).Conclusion: Higher SARC-F scores among younger adults were significantly associated with mortality. Early identification and intervention for individuals with SARC-F scores ≥1 may help mitigate risks related to sarcopenia in younger populations.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparison of oral health, nutrition, and swallowing function in older adults with and without sarcopenia: A cross-sectional study. 有和没有肌肉减少症的老年人口腔健康、营养和吞咽功能的比较：一项横断面研究。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-03-04 DOI: 10.1002/ncp.11283

Melike Yücel, Nezehat Özgül Ünlüer, Yasemin Ateş Sari

{"title":"A comparison of oral health, nutrition, and swallowing function in older adults with and without sarcopenia: A cross-sectional study.","authors":"Melike Yücel, Nezehat Özgül Ünlüer, Yasemin Ateş Sari","doi":"10.1002/ncp.11283","DOIUrl":"https://doi.org/10.1002/ncp.11283","url":null,"abstract":"Background: Sarcopenia, the age-related loss of muscle mass and strength, may impact the muscles involved in oral functions and swallowing, leading to challenges that may impact quality of life in older adults. The aim of the study was to compare oral health, swallowing function, and malnutrition of older adults with and without sarcopenia.Materials and methods: The cross-sectional study included volunteers ≥65 years of age. Sarcopenia status was evaluated by anthropometric (calf circumference and midupper arm circumference) and muscle strength (walking speed and handgrip strength) measurements. Oral health was assessed with the Oral Health Impact Profile (OHIP-14), swallowing function was assessed by the Eating Assessment Tool-10 (EAT-10), and nutrition status was determined using the Mini Nutritional Assessment.Results: This study included 65 older adults. The mean age was 80 years, 54% were female, and 43% were diagnosed with sarcopenia. Individuals with sarcopenia had a higher OHIP-14 score (which indicates poor quality of life related to oral and dental health, 16 ± 8 vs 11 ± 7; P = 0.008), were more likely to have a EAT-10 score ≥ 3 (indicating presence of dysphagia, 79% vs 41%; P = 0.002), and were more likely to be at risk for malnutrition (79% vs 54%; P = 0.03) compared with individuals without sarcopenia.Conclusions: Older adults with sarcopenia may be at risk for poor quality of life related to oral health, malnutrition and dysphagia. Further studies with long-term follow-up are needed to determine the long-term effects of sarcopenia on oral health, swallowing function, and malnutrition in older adults.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-dose vitamin D supplementation in patients with severe acute respiratory syndrome coronavirus 2 pneumonia hospitalized in a polyvalent intensive care unit: A retrospective cohort study. 在多价重症监护病房住院的严重急性呼吸综合征冠状病毒2型肺炎患者补充大剂量维生素D：一项回顾性队列研究

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-02-19 DOI: 10.1002/ncp.11277

Mafalda Vasconcelos, Bárbara Sucena Rodrigues, Ana Gonçalves

{"title":"High-dose vitamin D supplementation in patients with severe acute respiratory syndrome coronavirus 2 pneumonia hospitalized in a polyvalent intensive care unit: A retrospective cohort study.","authors":"Mafalda Vasconcelos, Bárbara Sucena Rodrigues, Ana Gonçalves","doi":"10.1002/ncp.11277","DOIUrl":"https://doi.org/10.1002/ncp.11277","url":null,"abstract":"Background and aims: The health benefits of vitamin D are far beyond bone mineral metabolism. Vitamin D has immunomodulator and anti-inflammatory properties and its role in critically ill patients is controversial. The purpose of the study is to understand whether high doses of vitamin D supplementation are beneficial in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia hospitalized in a polyvalent intensive care unit (ICU) and correlate to all-cause mortality, need for invasive mechanical ventilation, and duration of hospitalization.Methods: A retrospective study was conducted at a single polyvalent ICU, comparing patients supplemented with vitamin D with nonsupplemented patients. Eligible participants were adults with SARS-CoV-2 pneumonia admitted in this unit between April 14, 2020, and October 31, 2020. Demographic and clinical characteristics, comorbidities, and disease-related outcomes were extracted from electronic medical records.Results: No statistically significant differences were observed between the groups in terms of need for invasive mechanical ventilation or duration of hospitalization. Supplementation with vitamin D was associated with lower all-cause ICU, intrahospital, and total mortality.Conclusion: High-dose vitamin D supplementation was associated with a reduction of mortality in patients with severe SARS-CoV-2 pneumonia. Randomized clinical trials are needed to confirm these findings and to assess the optimal dosage of supplementation.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0