Nutrition in Clinical Practice最新文献_第2页

Use of glucagon-like peptide-1 receptor agonists and incretin mimetics for type 2 diabetes and obesity: A narrative review. 胰高血糖素样肽-1受体激动剂和肠促胰岛素模拟剂治疗2型糖尿病和肥胖症的应用综述

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-04-01 Epub Date: 2025-02-17 DOI: 10.1002/ncp.11279

Jason Zupec, Rebecca Munger, Alice Scaletta, Diane H Quinn

{"title":"Use of glucagon-like peptide-1 receptor agonists and incretin mimetics for type 2 diabetes and obesity: A narrative review.","authors":"Jason Zupec, Rebecca Munger, Alice Scaletta, Diane H Quinn","doi":"10.1002/ncp.11279","DOIUrl":"10.1002/ncp.11279","url":null,"abstract":"Incretin mimetics, including glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide agonists, have become first-line treatment options for the treatment of type 2 diabetes and obesity. Their therapeutic status is attributed to their high level of efficacy as well as positive impact on related comorbidities, such as sleep apnea and heart failure. Multiple incretin mimetics are currently available with different durations of drug action, dosing frequencies, and delivery devices. Patients may benefit from education on the proper drug administration, anticipated adverse effects, and nutrition considerations with treatment. Practitioners must monitor progress and support the patient to achieve maintenance doses for optimal weight reduction and diabetes-related outcomes. This review aims to present the current literature supporting US Food and Drug Administration-approved indications of incretin mimetics, equip healthcare professionals to optimize care for patients who are prescribed these agents, and provide insights into potential future applications, which may include dual- or triple-mechanism agents that are injected or administered orally. Additional studies are anticipated with existing and future incretin mimetics for the treatment of type 2 diabetes, obesity, and related comorbidities in a rapidly developing therapeutic pipeline.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":"327-349"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of adherence to oral nutritional supplements on nutrition status and muscle strength in patients with gastrointestinal cancer: A prospective observational longitudinal study. 坚持口服营养补充剂对胃肠道癌症患者营养状况和肌肉力量的影响：前瞻性纵向观察研究。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-04-01 Epub Date: 2024-11-07 DOI: 10.1002/ncp.11239

Wagner A Ferreira, Renata B Martucci, Nilian C Souza

{"title":"Impact of adherence to oral nutritional supplements on nutrition status and muscle strength in patients with gastrointestinal cancer: A prospective observational longitudinal study.","authors":"Wagner A Ferreira, Renata B Martucci, Nilian C Souza","doi":"10.1002/ncp.11239","DOIUrl":"10.1002/ncp.11239","url":null,"abstract":"Background: Given the lack of evidence regarding the effects of adherence to oral nutritional supplements (ONS) and the types of formulas used in clinical practice, we aimed to assess the impact of adherence to ONS and the high-protein formula on the nutrition status and muscle strength in patients with gastrointestinal cancer.Methods: This study evaluated newly diagnosed outpatients with esophageal, gastric, pancreatic, and colorectal cancer prescribed ONS. Nutrition status was assessed using the Patient-Generated Subjective Global Assessment (PG-SGA), and muscle strength was assessed using handgrip strength (HGS) dynamometry. ONS adherence was calculated as the ratio of self-reported intake to the prescribed amount and categorized as ≥80% or <80%.Results: A total of 54 patients were included. Most patients were ≥60 years of age (63%), were diagnosed with colorectal cancer (63%), were classified as stage III and IV (83%), and exhibited nutrition risk or malnutrition according to PG-SGA (89%). Patients with adherence ≥80% to ONS exhibited less weight loss and HGS reduction compared with patients with adherence <80% (P < 0.05). Although patients consuming a high-protein formula maintained HGS and those on a standard formula experienced a reduction, formula type did not predict HGS change in the multivariate analysis. ONS protein intake, adjusted for adherence, was a predictor of weight change (β: 0.09; 95% CI: 0.02-0.2; P = 0.011).Conclusion: Patients with adherence ≥80% to ONS experienced less reduction in both weight and HGS, whereas those consuming a high-protein formula maintained HGS. Notably, ONS protein intake, adjusted for adherence, was an independent predictor of weight change.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":"420-430"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142591316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eating behaviors of children with intestinal failure and those who achieve enteral autonomy: An observational cross-sectional study. 肠衰竭和肠内自主患儿的饮食行为：一项观察性横断面研究。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-04-01 Epub Date: 2024-12-20 DOI: 10.1002/ncp.11268

Giovana Q Pires, Alana V Signorini, Cristina Miller, Juliana M Giesta, Marília R Ceza, Marina R Adami, Carlos O Kieling, Helena A S Goldani

{"title":"Eating behaviors of children with intestinal failure and those who achieve enteral autonomy: An observational cross-sectional study.","authors":"Giovana Q Pires, Alana V Signorini, Cristina Miller, Juliana M Giesta, Marília R Ceza, Marina R Adami, Carlos O Kieling, Helena A S Goldani","doi":"10.1002/ncp.11268","DOIUrl":"10.1002/ncp.11268","url":null,"abstract":"Background: Children with intestinal failure (IF) receiving prolonged parenteral nutrition (PN) are exposed to risk factors that predispose them to developing disordered eating behavior. This study aimed to assess the food interest patterns of PN-dependent children with IF and those who achieved enteral autonomy (EA).Methods: A cross-sectional study was conducted in children aged 1-14 years with IF currently receiving PN for >60 days and in children who achieved EA. The American Speech-Language-Hearing Association-National Outcomes Measurement System (ASHA-NOMS) scale for oral feeding assessment and Children's Eating Behavior Questionnaire (CEBQ) for eating behavior were used. Children were divided into two groups, G1 (currently using PN) and G2 (achieved EA by discontinuation of PN), for the analysis of each subscale of the questionnaire. The PN dependency index (PNDI) was also assessed.Results: Fifty-one children were evaluated, and the median (IQR) age was 47.0 (26.0-69.0) months. Thirty-five (68.6%) children were in G1, and 16 (31.4%) were in G2. Children in G2 had better mean scores than those in G1 on the satiety responsiveness, food responsiveness, and enjoyment of food subscales. These scores were significantly different among children with high/moderate PN dependence compared with those with mild dependence or those who achieved EA.Conclusion: Compared with children who achieved EA, those with PN-dependent IF showed food avoidance patterns of less interest in and enjoyment of food. This pattern was more pronounced in those with moderate/high dependence on PN.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":"431-438"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Need for Gastroschisis Feeding Protocols. 需要制定胃畸形喂养协议。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-04-01 Epub Date: 2024-11-23 DOI: 10.1002/ncp.11248

Amit Trivedi, Jeewan Jyoti, Kristen James-Nunez, Kaye Spence, Bronwyn Parkinson, Gordon Thomas

引用次数: 0

Elastic sac to support oral feeding performance of preterm infants: Crossover randomized controlled study. 支持早产儿口腔喂养的弹性囊：交叉随机对照研究

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-04-01 Epub Date: 2024-06-01 DOI: 10.1002/ncp.11161

Canan Genç, Duygu Gözen, Fatma Narter

{"title":"Elastic sac to support oral feeding performance of preterm infants: Crossover randomized controlled study.","authors":"Canan Genç, Duygu Gözen, Fatma Narter","doi":"10.1002/ncp.11161","DOIUrl":"10.1002/ncp.11161","url":null,"abstract":"Background: Swaddling is recommended for preterm infants during feeding. Swaddling preterm infants with elastic cotton materials allows infants to easily stretch and move their extremities. This study aimed to assess the effect of bottlefeeding in a novel \"elastic sac\" on physiological parameters and feeding performance of preterm infants.Methods: A randomized controlled, crossover trial was conducted with total of 26 preterm infants at 26-36+6 weeks of gestation. Infants randomly assigned to group 1 (n = 13) were bottlefed in an elastic sac (researcher-designed single-piece pouch made of soft, elastic cotton) for the first feeding and in normal clothes for the next feeding. Infants randomly assigned to group 2 (n = 13) were fed first in normal clothes and then in the elastic sac. The physiological parameters and feeding performance of the infants were assessed during each feeding.Results: Preterm infants fed in the elastic sac had lower heart rate and higher oxygen saturation during and after feeding than infants fed in normal clothes (P < 0.05). Although all values were within clinically normal ranges, the findings suggest that feeding preterm infants in the elastic sac had a favorable effect on physiological parameters compared with feeding in normal clothes. There was no significant difference in the infants' feeding performance (P > 0.05).Conclusion: A semielevated right lateral position and flexed body posture are recommended while feeding preterm infants, which can be easily maintained using the elastic sac. Feeding preterm infants in an elastic sac may support physiologic stability during oral feeding.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":"465-474"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141186579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of home-blended tube feedings in pediatric patients with gastrostomy tubes: A retrospective study. 家庭混合管喂养在小儿胃造口管患者中的作用：一项回顾性研究。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-04-01 Epub Date: 2024-12-17 DOI: 10.1002/ncp.11261

Marta Germán-Díaz, Eva Peña, Raquel Núñez-Ramos, María Jesús Guijarro, Cristina Marín-Arriscado Arroba

{"title":"Role of home-blended tube feedings in pediatric patients with gastrostomy tubes: A retrospective study.","authors":"Marta Germán-Díaz, Eva Peña, Raquel Núñez-Ramos, María Jesús Guijarro, Cristina Marín-Arriscado Arroba","doi":"10.1002/ncp.11261","DOIUrl":"10.1002/ncp.11261","url":null,"abstract":"Background: Both blended tube feed (BTF) and commercial tube feed (CTF) can be administered through a gastrostomy tube (GT). There is very little evidence about using home BTF (HBTF). Nevertheless, families increasingly request this type of nutrition because they attribute some benefits to it. Our objective was to evaluate the efficacy and safety of using HBTF via GT as an alternative to CTF.Methods: Single-center, retrospective, and observational study of patients under 18 years old who underwent GT between 2014 and 2020. We reviewed demographics, anthropometrics, clinical characteristics, and types of diet and gastrointestinal (GI) symptoms over 12 months after the placement of the GT.Results: Forty patients (40% boys) were included. The median age at GT placement was 15 months (interquartile range 5-57.5). The most common underlying diagnosis was a neurological disorder (45%). In 75% of patients, Nissen fundoplication was performed. At the 12-month follow-up, 18 patients (45%) were receiving 100% HBTF, 14 (35%) were receiving a mixed diet (HBTF + CTF), four (10%) were receiving 100% CTF, and four (10%) were no longer using the GT. Those with a 100% HBTF diet showed a statistically significant higher weight at the 12-month follow-up than those who had received any percentage of CTF. No other statistically significant differences in anthropometric indices or GI symptoms were found between the two groups. Only three cases of mechanical complications were reported.Conclusion: In our experience, using HBTF via the GT provides an alternative to CTF in pediatric patients who require enteral nutrition.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":"457-464"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implementation of standardized feeding pathways for infants with gastroschisis to improve patient outcomes: A quality improvement project in a level IV surgical NICU. 为患有胃裂的婴儿实施标准化喂养路径，以改善患者预后：四级手术新生儿重症监护室的质量改进项目。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-04-01 Epub Date: 2024-09-25 DOI: 10.1002/ncp.11216

Andrea Adler, Kadakkal Radhakrishnan, Natalie Yeaney

{"title":"Implementation of standardized feeding pathways for infants with gastroschisis to improve patient outcomes: A quality improvement project in a level IV surgical NICU.","authors":"Andrea Adler, Kadakkal Radhakrishnan, Natalie Yeaney","doi":"10.1002/ncp.11216","DOIUrl":"10.1002/ncp.11216","url":null,"abstract":"Gastroschisis is a leading cause of pediatric intestinal failure. Feeding guidelines may lead to improved patient outcomes including decreased time to reach full feeds, a reduction in the duration of parenteral nutrition, and reduced length of stay. However, there is limited evidence on what the ideal feeding guidelines are for this complex gastrointestinal diagnosis. In this quality improvement project, after completing a literature review, we created three pathways based on the complexity of the gastroschisis. We reviewed historical data without a defined feeding pathway/guideline to our newly created pathways in the intervention group. The study included 35 patients with varying degrees of gastroschisis complexity, consisting of 9 current patients (October 2021-December 2022) who were provided with defined feeding pathways and 26 historical patients before the protocol was implemented (January 2015-August 2021). There were no significant differences in the number of days required for full feeds between the two groups. However, the mean duration of parenteral nutrition was 18.9 days (95% CI, -31.8 to -7.0) shorter in the intervention group. Although not statistically significant, the patients in the intervention group had a mean length of stay that was 13.1 days (95% CI, -50.0 to 25.4) shorter than the historical group. The creation of standardized feeding guidelines for the gastroschisis population resulted in a statistically nonsignificant decrease in time to reach full enteral feeds, a statistically significant reduced duration of parenteral nutrition, and a statistically nonsignifiant decreased length of stay.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":"496-507"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term enteral nutrition with a nasogastric tube can be safe and effective: A case report. 鼻胃管长期肠内营养安全有效1例报告。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-04-01 Epub Date: 2024-12-20 DOI: 10.1002/ncp.11263

James M Duerksen, Bram Ramjiawan, Donald R Duerksen

{"title":"Long-term enteral nutrition with a nasogastric tube can be safe and effective: A case report.","authors":"James M Duerksen, Bram Ramjiawan, Donald R Duerksen","doi":"10.1002/ncp.11263","DOIUrl":"10.1002/ncp.11263","url":null,"abstract":"Home enteral nutrition (HEN) is a vital feeding practice for those who have chronic disorders that prevent them from eating normally. Although short-term feeding is predominantly done via nasogastric (NG) tubes and long-term feeding is done via percutaneous endoscopic gastrostomy (PEG) tube, we present a case that demonstrates that the long-term use of NG tubes may be possible. Our case involves an adult woman who has been fed via an NG tube for >3 years with no complications. She has had three replacement tubes inserted over these 3 years and has not required any healthcare visits related to tube dysfunction or complications. She continues to do well. A literature search determined that there are no reports of long-term use (greater than a year) of NG feeding tubes in outpatient adults, and thus the true rate of complications related to NG tubes is unknown. We review the reported complications associated with long-term PEG tubes. Although PEGs are typically regarded as safer in long-term feeding situations, this case demonstrates that NG tubes could prove effective under certain circumstances in which the insertion of a PEG may not be possible.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":"492-495"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How to educate patients and caregivers on end-of-life nutrition care and support. 如何教育患者和护理人员临终营养护理和支持。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-04-01 Epub Date: 2025-01-28 DOI: 10.1002/ncp.11272

Denise Baird Schwartz, Sandra Wolfe Citty, Albert Barrocas, Julie O'Sullivan-Maillet

{"title":"How to educate patients and caregivers on end-of-life nutrition care and support.","authors":"Denise Baird Schwartz, Sandra Wolfe Citty, Albert Barrocas, Julie O'Sullivan-Maillet","doi":"10.1002/ncp.11272","DOIUrl":"10.1002/ncp.11272","url":null,"abstract":"Background: There are numerous articles, book chapters, and published guidelines on the topic of clinical ethics in the use of artificially administered nutrition and hydration, which often incorporates end-of-life (EOL) nutrition care and support. Components of clinical ethics involve the importance of ethical principles, patient-centered care, and shared decision-making. However, there is sparse information on how to educate patients and caregivers on this subject.Methods: Initially, PubMed and the Cochrane Library were used to find articles on the subject. Articles were reviewed and new concepts were identified to include.Results: There is a practice gap with not applying clinical ethics in practice. The application of clinical ethics, which includes the teach-back method of education, soft skills and behavioral skills training, and potential sacred moments, is not well addressed in the literature. Demonstration of the process of incorporating clinical ethics into practice is beneficial in helping educate clinicians so they can then effectively educate the patient and caregiver on EOL nutrition care and support. Reasons for not applying clinical ethics in actual clinical practice may be because of clinicians not receiving training, the lack of opportunity to observe the technique applied in actual clinical practice, or possibly concern for the presumed additional time required in clinical practice to apply clinical ethics.Conclusion: Educating patients and caregivers on EOL nutrition care and support presupposes engaging, educating, and empowering clinicians about clinical ethics by demonstrating the process and encouraging educators to incorporate the information in an interdisciplinary/interprofessional curriculum.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":"288-306"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A prospective observational study on microbiological isolation in low-profile gastrostomy's feeding extension sets in children on long-term home enteral nutrition. 关于长期在家接受肠内营养的儿童低位胃造口术喂食扩展装置微生物分离的前瞻性观察研究。

IF 2.1 4区医学

Nutrition in Clinical Practice Pub Date : 2025-04-01 Epub Date: 2024-11-27 DOI: 10.1002/ncp.11252

Silvia Rodriguez-Manchon, Carmen Sanchez Fernandez-Bravo, Belén Hernández-Milán, Elvira Cañedo-Villarroya, Mercedes Alonso-Sanz, Consuelo Pedron-Giner

{"title":"A prospective observational study on microbiological isolation in low-profile gastrostomy's feeding extension sets in children on long-term home enteral nutrition.","authors":"Silvia Rodriguez-Manchon, Carmen Sanchez Fernandez-Bravo, Belén Hernández-Milán, Elvira Cañedo-Villarroya, Mercedes Alonso-Sanz, Consuelo Pedron-Giner","doi":"10.1002/ncp.11252","DOIUrl":"10.1002/ncp.11252","url":null,"abstract":"Background: Although reuse of enteral feeding equipment has been linked to risk of microbial contamination and risk of infection, there is a paucity of research in this area. Per the manufacturer's instructions low-profile gastrostomy feeding extension sets (LPG-FES) may be reusable for the same patient, but there are no recommendations on replacement intervals.Methods: We conducted a prospective observational study to analyze and compare the contamination rate of LPG-FES after 15 (T1) and after 30 days (T2) of regular use. We included children 2-18 years of age exclusively receiving long-term home enteral nutrition (HEN) via LPG.Results: We included 17 patients with a median age of 5 years (interquartile range: 3-8 years). We did not find statistically significant differences in microbial overgrowth comparing LPG-FES obtained after 15 or 30 days of use, although overgrowth was slightly higher in LPG-FES used for 30 days (64.7% and 70.6% vs 52.9% and 58.8%). Every patient presented at least one positive culture, either in T1 or T2. Candida parapsilosis was globally the most frequent microbiological finding. We found no relation between duration of HEN and type of feeding and positive culture at T1 and T2. We found no symptoms of local nor systemic infection during the study period.Conclusion: Despite the high rate of microbial overgrowth in the LPG-FES, no patient had clinical symptoms of infection secondary to this finding. Microbiological isolation in FES may represent only a form of contamination without clinical implications, which raises doubts on possible LPG-FES dwell times.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":"450-456"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142731150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0