Nutrition in Clinical Practice最新文献

Agreement between predictive equations and indirect calorimetry in estimating resting metabolic rate among free-living older adults with sarcopenia: A prospective observational study. 预测方程和间接量热法在估计自由生活老年人肌肉减少症患者静息代谢率方面的一致性：一项前瞻性观察研究。

IF 2.2 4区医学

Nutrition in Clinical Practice Pub Date : 2026-05-07 DOI: 10.1002/ncp.70131

Qi Dong, Lu Wu, Jiao Liu, Li Wang, Danye Niu, Ning Li, Yanmin Zheng, Lei Ding, Yating Ma, Jiaxian Liu, Bo Wang, Haitao Wang, Ming Zhou

{"title":"Agreement between predictive equations and indirect calorimetry in estimating resting metabolic rate among free-living older adults with sarcopenia: A prospective observational study.","authors":"Qi Dong, Lu Wu, Jiao Liu, Li Wang, Danye Niu, Ning Li, Yanmin Zheng, Lei Ding, Yating Ma, Jiaxian Liu, Bo Wang, Haitao Wang, Ming Zhou","doi":"10.1002/ncp.70131","DOIUrl":"https://doi.org/10.1002/ncp.70131","url":null,"abstract":"Resting metabolic rate (RMR) accounts for the largest proportion of daily total energy expenditure. The purpose of this study is to systematically evaluate the agreement of predictive equations for RMR and indirect calorimetry (IC) in a population with sarcopenia. The study included 43 individuals with sarcopenia aged 60 and above (diagnosed according to the AWGS 2019 criteria for sarcopenia). One-on-one measurements and questionnaires were used to obtain information including height, weight, body composition, gait speed, and grip strength. A total of 11 different predictive equations were used to estimate RMR and were compared with the IC in multiple dimensions. The RMR of the study participants ranged from 652 to 1244 kcal/day, with an average of 920.5 ± 150.3 kcal/day. All predictive equations exhibited an accuracy rate of less than 40%, with the Mifflin equation based on body weight (Mifflin_W) showing the lowest bias (16.54%), the lowest root mean square error (RMSE) value (216.51 kcal/day), the highest Lin's Concordance Correlation Coefficient (CCC) value (0.40) and the lowest median absolute percentage error (MAPE) (16.52%). The predictions of the Porter equations were not influenced by age or body mass index (BMI), making its predictions more stable, whereas the biases of other equations were significantly affected by age or BMI. Despite overall poor performance by all equations, the Mifflin_W equation showed the best agreement with IC measurements and may be used with caution when IC is unavailable, noting its tendency to overestimate RMR.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147840389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survey to assess the economic stability and mental health of households with people receiving enteral and parenteral nutrition. 对接受肠内和肠外营养的家庭进行经济稳定和心理健康评估的调查。

IF 2.2 4区医学

Nutrition in Clinical Practice Pub Date : 2026-05-07 DOI: 10.1002/ncp.70133

Gabriela Gardner, Ryan Butcher, Brooks D Cash

{"title":"Survey to assess the economic stability and mental health of households with people receiving enteral and parenteral nutrition.","authors":"Gabriela Gardner, Ryan Butcher, Brooks D Cash","doi":"10.1002/ncp.70133","DOIUrl":"https://doi.org/10.1002/ncp.70133","url":null,"abstract":"Background: The landscape of nutrition support faces challenges, including rising costs, product shortages, reimbursement gaps, and infusion providers closing. This nationwide survey aimed to describe the perceptions and attitudes related to costs, therapy access, and mental health among households with at least one family member requiring enteral nutrition, parenteral nutrition, or a combination of the two.Methods: A 10-item online survey was available for 8 weeks to households of adult (>18 years old) and pediatric patients (1-17 years old) currently receiving or who had received enteral or parenteral nutrition at home within the past 12 months. The survey explored beliefs and attitudes regarding financial impact, access to care, food security, coping mechanisms, and mental health.Results: Of the 182 participants, 42.9% were on enteral nutrition, 32.4% were on parenteral nutrition, and 24.7% were both. Overall, 52% reported a degree of financial concern due to nutrition therapy costs. About 51% of families described difficulties obtaining nutrition therapy related to cost or insurance coverage. A total of 52.7% of households reported worrying about food security. Over half, 63.7%, reported an impact on their mental health.Conclusion: Our findings support that various factors, including the cost of therapy, can negatively impact the economic stability and mental health of families with a member on enteral or parenteral nutrition. These findings highlight the importance of screening for social determinants of health to identify opportunities for intervention through the provision of additional resources and patient advocacy.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147840397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of total gastrectomy on weight and body composition: A retrospective study. 全胃切除术对体重和体成分影响的回顾性研究。

IF 2.2 4区医学

Nutrition in Clinical Practice Pub Date : 2026-05-04 DOI: 10.1002/ncp.70126

Teja Tadicherla, Andrew J Sinnamon, Rosemaria Thomas, Shaffer Mok, Sean Dineen, Erin N Gurd, Nathan H Parker, Rutika J Mehta, Jose M Pimiento

{"title":"Effect of total gastrectomy on weight and body composition: A retrospective study.","authors":"Teja Tadicherla, Andrew J Sinnamon, Rosemaria Thomas, Shaffer Mok, Sean Dineen, Erin N Gurd, Nathan H Parker, Rutika J Mehta, Jose M Pimiento","doi":"10.1002/ncp.70126","DOIUrl":"https://doi.org/10.1002/ncp.70126","url":null,"abstract":"Background: Patients undergoing total gastrectomy (TG) for gastric cancer experience significant weight loss and are at risk for nutritional deficiencies. This study aimed to assess body composition changes following TG, focusing on contribution of skeletal muscle mass loss versus adipose loss.Methods: This retrospective analysis examines patients who underwent TG at a major cancer center (2014-2021). Longitudinal analysis with regression identified factors associated with rate of body mass index (BMI) change. Cross-sectional CT scan imaging quantified body mass loss, including skeletal muscle area (SMA), skeletal muscle index (SMI), subcutaneous fat area (SFA), and visceral fat area (VFA).Results: Fifty-two TG patients were identified (median age 63 y; 54% male). Higher preoperative BMI predicted greater postoperative weight loss, with BMI > 30 losing more than BMI < 30 (P < 0.001). Weight loss was non-linear, peaking at 6 months (-17%), stabilizing by 12 months, then gradually increasing (P = 0.039). SMA and SMI decreased by 11% at 6 months for both, respectively, with gradual recovery after 12 months. SFA and VFA decreased significantly over 3 years, with peak fat loss evident at 12 months post-surgery, SFA decreased 64% from baseline and VFA decreased 95% from baseline, with minimal recovery thereafter. Skeletal muscle loss peaked 12 months post-TG, including 66% of males and 77% of females, with slight decreases in low skeletal muscle rates at 24 months.Conclusion: Weight loss post-TG follows a non-linear pattern, with peak loss at 6 months and stabilization at 12 months. Most weight loss is due to loss of visceral and subcutaneous adipose with substantially less muscle loss. Nevertheless, ongoing monitoring for sarcopenia is warranted in both sexes post-TG.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147840430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A skeleton in the closet has become an elephant in the exam room: Rethinking our diagnosing of malnutrition in 2026. 衣橱里的骷髅变成了诊断室里的大象：重新思考我们对2026年营养不良的诊断。

IF 2.2 4区医学

Nutrition in Clinical Practice Pub Date : 2026-05-03 DOI: 10.1002/ncp.70128

David S Seres

引用次数: 0

Growth and human milk intake outcomes from postdischarge feedings among very-low-birth-weight preterm infants: A systematic review. 极低出生体重早产儿出院后喂养的生长和母乳摄入结果：一项系统综述。

IF 2.2 4区医学

Nutrition in Clinical Practice Pub Date : 2026-04-29 DOI: 10.1002/ncp.70127

Tara Rebele, Allison Gomes, Melanie Newkirk, Mina Ghajar, Laura Byham-Gray, Jane Ziegler

{"title":"Growth and human milk intake outcomes from postdischarge feedings among very-low-birth-weight preterm infants: A systematic review.","authors":"Tara Rebele, Allison Gomes, Melanie Newkirk, Mina Ghajar, Laura Byham-Gray, Jane Ziegler","doi":"10.1002/ncp.70127","DOIUrl":"https://doi.org/10.1002/ncp.70127","url":null,"abstract":"Background: Preterm infants of <34 weeks gestation or <1500 g are at risk for postnatal growth failure and often require nutrition support after discharge. Despite expert recommendations for postdischarge human milk (HM) fortification or nutrient-enriched formula feeding, the effects of current feeding strategies on growth and HM intake remain unclear. This systematic review evaluated the impact of postdischarge fortified expressed HM or direct breastfeeding (BF) with postdischarge formula (PDF) bottle feeds compared to unfortified HM or BF with standard term formula bottle feeds on growth and HM intake outcomes through 6 and 12 months corrected age (CA).Methods: A systematic search of eight databases and grey literature sources was conducted for studies published in English since 2012 identifying 3146 studies. Risk of bias was assessed using standardized Cochrane RoB 2 and ROBINS-I tools. Meta-analysis was not conducted due to heterogeneity in interventions, outcome timing, and outcome metrics; results were narratively synthesized.Results: Four studies (n = 2 randomized controlled trials, n = 2 cohorts), including 548 preterm infants, met eligibility criteria. Two studies showed significantly greater weight gain, and one showed significantly greater head circumference in the fortified groups at 6 months CA compared to the unfortified groups. Length differences were not significant. Three studies reporting HM intake found comparable or greater HM intake in the fortified groups.Conclusion: Current evidence suggests that postdischarge fortified HM or direct BF with supplemental PDF bottle feeds may support improved weight and head circumference outcomes without compromising HM intake. However, methodological variability highlights the need for standardized, prospective studies.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative effectiveness of different nutrition assessment tools (MNA, NRS 2002, MUST) in identifying pressure injury risk among patients who had a stroke: A retrospective cohort study. 不同营养评估工具（MNA, NRS 2002， MUST）在卒中患者中识别压力损伤风险的比较有效性：一项回顾性队列研究。

IF 2.2 4区医学

Nutrition in Clinical Practice Pub Date : 2026-04-29 DOI: 10.1002/ncp.70119

Liping Yin, Jingjing Kong, Jia Liu

{"title":"Comparative effectiveness of different nutrition assessment tools (MNA, NRS 2002, MUST) in identifying pressure injury risk among patients who had a stroke: A retrospective cohort study.","authors":"Liping Yin, Jingjing Kong, Jia Liu","doi":"10.1002/ncp.70119","DOIUrl":"https://doi.org/10.1002/ncp.70119","url":null,"abstract":"Background: This study aimed to compare effectiveness of the Mini Nutritional Assessment (MNA), Nutritional Risk Screening 2002 (NRS 2002), and Malnutrition Universal Screening Tool (MUST) in identifying pressure injury risk among patients who had a stroke.Methods: This retrospective cohort study collected demographic characteristics MNA, NRS 2002, MUST scores, and key nutritional parameters measured within 24 h of admission. High-risk groups are defined as MUST scores ≥1 point, NRS 2002 scores ≥3 points, and MNA scores <17 points. Pressure injury diagnosis adhered to National Pressure Injury Advisory Panel/European Pressure Ulcer Advisory Panel criteria.Results: A total of 505 patients who had a stroke were included of which 85 developed a pressure injury. There was no difference in age, sex or type of stroke between the two groups. MUST high-risk group had the highest pressure injury incidence (35.1%) and Kappa value (0.350). The NRS 2002 and MNA high-risk group showed pressure injury incidences of 27.1% and 26.2%, with Kappa values of 0.202 and 0.175. Receiver operating characteristic (ROC) curve analysis confirmed MUST had optimal predictive performance (0.877, 95% CI: 0.833-0.921) and specificity (93.6%). The area under the curve (AUC) values for NRS 2002 and MNA were 0.760 (95% CI: 0.703-0.816) and 0.732 (95% CI: 0.679-0.786) with specificities of 66.7% and 64.7%.Conclusion: MUST demonstrates superior predictive performance (highest AUC and specificity) and risk stratification consistency, outperforming the NRS 2002 and MNA. Therefore, MUST appears to be the most useful among the three tools evaluated, but further research is needed to confirm its predictive ability.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implementing the Global Leadership Initiative on Malnutrition framework for diagnosing malnutrition by registered dietitians: A quality improvement project. 实施全球营养不良领导倡议框架，由注册营养师诊断营养不良：一个质量改进项目。

IF 2.2 4区医学

Nutrition in Clinical Practice Pub Date : 2026-04-27 DOI: 10.1002/ncp.70129

Stacy Pelekhaty, Alison Winter-Lai

{"title":"Implementing the Global Leadership Initiative on Malnutrition framework for diagnosing malnutrition by registered dietitians: A quality improvement project.","authors":"Stacy Pelekhaty, Alison Winter-Lai","doi":"10.1002/ncp.70129","DOIUrl":"https://doi.org/10.1002/ncp.70129","url":null,"abstract":"Malnutrition presents a significant burden to healthcare organizations, and worsens clinical outcomes. Despite this, the frequency of malnutrition diagnosis remains far below known prevalence. Multiple validated frameworks for diagnosing malnutrition exist, the most recent being the Global Leadership Initiative on Malnutrition (GLIM). The purpose of this article is to describe the implementation of the GLIM framework using a multi-disciplinary co-documentation process at one institution. Preimplementation analyses were conducted demonstrating wide discrepancy in frequency and severity of malnutrition diagnoses made by registered dietitian nutritionists (RDNs) and licensed independent practitioners in a one month period with minimal overlap. This was associated with coding capture in the lowest quartile compared with like organizations. Institutional support was obtained for a co-documentation process to include all required elements identified by the coding team. Nutrition leadership reviewed malnutrition frameworks and identified that transition to GLIM would streamline diagnosis in many cases. Education of RDNs focused on interprofessional collaboration and transition to the new framework. Post-implementation, monthly monitoring of co-signature rates on malnutrition notes improved from 72% initially to 90% one year after implementation. Coding capture of malnutrition diagnoses doubled from 4.8% of admissions in January of 2020 to 10% of admissions in mid 2021, increasing institutional performance to the median compared with like organizations. This has been sustained for over 5 years, as demonstrated by 2025 data, and denials remain low. Implementation of GLIM was well accepted by practicing RDNs and supported a collaborative process that improved multi-professional malnutrition documentation.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Micronutrient deficiencies in hepatic cirrhosis: Navigating challenges to assessment and implications for clinical management: A narrative review. 肝硬化的微量营养素缺乏：评估的挑战和临床管理的意义：叙述性回顾。

IF 2.2 4区医学

Nutrition in Clinical Practice Pub Date : 2026-04-22 DOI: 10.1002/ncp.70124

Holly Estes-Doetsch, Michael Wellner, Jane Ziegler

引用次数: 0

Comparative five-year mortality risk in older adults with sarcopenia and sarcopenic obesity: A retrospective cohort analysis. 老年肌肉减少症和肌肉减少性肥胖患者的5年死亡风险比较：回顾性队列分析

IF 2.2 4区医学

Nutrition in Clinical Practice Pub Date : 2026-04-18 DOI: 10.1002/ncp.70125

Ezgi Akandere Barlas, Sibel Akın, Neslihan Doğan, Gülşah Güneş Şahin, Funda İpekten

{"title":"Comparative five-year mortality risk in older adults with sarcopenia and sarcopenic obesity: A retrospective cohort analysis.","authors":"Ezgi Akandere Barlas, Sibel Akın, Neslihan Doğan, Gülşah Güneş Şahin, Funda İpekten","doi":"10.1002/ncp.70125","DOIUrl":"https://doi.org/10.1002/ncp.70125","url":null,"abstract":"Background: Sarcopenia and sarcopenic obesity (SO) are increasingly prevalent among older adults and are associated with elevated mortality risk. However, the prognostic differences between these phenotypes remain unclear. This study aimed to compare five-year all-cause mortality between older adults with isolated sarcopenia and those with SO.Methods: In this retrospective cohort study, we analyzed 730 community-dwelling individuals aged ≥60 years who attended a geriatrics outpatient clinic between 2018 and 2023. Participants were categorized as having sarcopenia, having SO, or controls based on EWGSOP2 criteria and BMI ≥ 30 kg/m². Comprehensive geriatric assessments-including evaluations of nutrition, cognition, function, and frailty-were performed at baseline. Mortality data were obtained from institutional records. Survival outcomes were assessed using Kaplan-Meier analysis and Cox proportional hazards models.Results: Of the participants, 123 had sarcopenia and 174 had sarcopenic obesity (SO). Over a median follow-up of five years, both groups exhibited significantly higher mortality rates than controls. Individuals with isolated sarcopenia showed the lowest survival probability (log-rank p < 0.001). In multivariable Cox analysis, chronic kidney disease, lower BMI, and older age were independent predictors of mortality.Conclusion: Both individuals with sarcopenia and those with SO are associated with increased five-year mortality in older adults. However, individuals with isolated sarcopenia have a higher risk than those with SO, suggesting that excess adiposity may partially mitigate the adverse effects of muscle loss.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147717498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A micro-costing analysis of standardized versus individualized parenteral nutrition in preterm neonates. 早产儿标准化与个体化肠外营养的微观成本分析。

IF 2.2 4区医学

Nutrition in Clinical Practice Pub Date : 2026-04-16 DOI: 10.1002/ncp.70123

Eleonora Castellana, Francesco Cresi, Alessandra Coscia, Marco Limone, Giampiero Vaudano, Maria Francesca Campagnoli, Maria Rachele Chiappetta

{"title":"A micro-costing analysis of standardized versus individualized parenteral nutrition in preterm neonates.","authors":"Eleonora Castellana, Francesco Cresi, Alessandra Coscia, Marco Limone, Giampiero Vaudano, Maria Francesca Campagnoli, Maria Rachele Chiappetta","doi":"10.1002/ncp.70123","DOIUrl":"https://doi.org/10.1002/ncp.70123","url":null,"abstract":"Background: The main aim of this study was to compare the costs of using standardized parenteral nutrition (PN) bags versus individualized PN bags for very low birth weight and extremely low birth weight preterm infants in the neonatal intensive care unit.Methods: A micro-costing analysis was conducted from November 1, 2022 through October 31, 2023 on both individualized and standard PN bags.Results: During the analysis period, 660 individual bags and 3700 standard bags were used. The average cost per individualized PN bag versus standardized bag was $160.92 versus $62.92 respectively. Standard bags were found to be 60.9% more cost-effective.Conclusion: The study concluded that standard PN bags are more cost-effective for very low birth weight and extremely low birth weight preterm patients. These findings support the potential shift towards using standardized PN in hospitals to manage resources effectively. Pharmacists can utilize these results to promote guideline-based use of standardized PN.","PeriodicalId":19354,"journal":{"name":"Nutrition in Clinical Practice","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147691297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0