Teresa DeAtley, Abby Baker, Rachel Denlinger-Apte, Adedotun Ogunbajo, Ursula Martinez, Rachel Ceballos, David W Wetter, Don Operario, Trace Kershaw, Kristi E Gamarel, Arjee Restar
{"title":"Assessing Tobacco Harm Perceptions among Transgender and Nonbinary Adults: Results from a Community Informed State-wide Survey.","authors":"Teresa DeAtley, Abby Baker, Rachel Denlinger-Apte, Adedotun Ogunbajo, Ursula Martinez, Rachel Ceballos, David W Wetter, Don Operario, Trace Kershaw, Kristi E Gamarel, Arjee Restar","doi":"10.1093/ntr/ntaf050","DOIUrl":"https://doi.org/10.1093/ntr/ntaf050","url":null,"abstract":"<p><strong>Introduction: </strong>Epidemiologic data has documented elevated levels of smoking and vaping among transgender and nonbinary (trans) adults. Yet, knowledge about nicotine and tobacco harm perceptions are not well understood within this population.</p><p><strong>Methods: </strong>Utilizing data from a community-informed study conducted among transgender adults in Washington state from March-April 2023, we explored gender differences in the distribution of tobacco harm perceptions (knowledge, addiction, and harm perceptions). Using logistic and multinomial regression models, we tested predictors and correlates of accurate and inaccurate harm perceptions controlling for age, race, income, health care information trust, current cigarette use, e-cigarette use, and depression and anxiety symptoms.</p><p><strong>Results: </strong>A total of 770 trans individuals completed the survey. Overall, 83.6% identified as a woman, 8.7% as a man, and 7.7% as nonbinary, gender nonconforming, or genderqueer. Almost half (43.64%) identified as cigarette users and 14.55% as e-cigarette users. The vast majority of study participants (93.25%) incorrectly believed that nicotine causes cancer and that cigarettes with lower levels of nicotine were less harmful to a person's health than regular cigarettes (69.87%). Experiencing elevated symptoms of depression, and having lower income were associated with more inaccurate perceptions about tobacco-related harms and addiction potential.</p><p><strong>Conclusions: </strong>Direct messaging is needed to inform transgender individuals that nicotine is not the primary chemical in cigarettes that causes cancer and that nicotine is the primary chemical responsible for addiction. Trans women and nonbinary individuals may need specific messaging regarding the perceived risks and harms of tobacco use.</p><p><strong>Implications: </strong>Very little research has focused on exploring tobacco-related harm perceptions among gender diverse identities. Among the studies that exist, gender identity is combined with sexual identity. Our study aims to address this gap by reporting harm perceptions in a trans only sample, focusing on two distinct harm perception domains.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Warnings and Other Communications to Promote Tobacco Cessation.","authors":"Amy K Ferketich","doi":"10.1093/ntr/ntaf061","DOIUrl":"https://doi.org/10.1093/ntr/ntaf061","url":null,"abstract":"","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melina Joseph, Meghan E Morean, Ran Wu, Suchitra Krishnan-Sarin, Stephanie S O'Malley, Krysten W Bold
{"title":"Examining E-Cigarette Flavor Use and Preference by Menthol Cigarette Status and Quit Duration Among US Adults Using E-Cigarettes in a Smoking Cessation Attempt.","authors":"Melina Joseph, Meghan E Morean, Ran Wu, Suchitra Krishnan-Sarin, Stephanie S O'Malley, Krysten W Bold","doi":"10.1093/ntr/ntaf059","DOIUrl":"10.1093/ntr/ntaf059","url":null,"abstract":"<p><strong>Introduction: </strong>Switching to e-cigarettes may help some adults quit smoking. More research is needed to understand the role of flavors in e-cigarettes among adults who smoke menthol and non-menthol cigarettes to inform policy and efforts to reduce cigarette use.</p><p><strong>Methods: </strong>Cross-sectional survey data from adults who used e-cigarettes to quit smoking (N = 857) were used to examine e-cigarette flavors used and preferred during the smoking cessation attempt and differences by cigarette type (menthol vs. non-menthol). A general linear model was used to examine the main effects and interaction of cigarette type (menthol vs. non-menthol) and preferred e-cigarette flavor for quitting on duration of smoking abstinence.</p><p><strong>Results: </strong>Adults who smoked menthol cigarettes were more likely to prefer menthol/mint vs. tobacco (AOR = 12.29, 95% CI = 7.42-20.34) or other e-cigarette flavors (AOR = 7.55, 95% CI = 4.22-13.50). However, there was a significant interaction between cigarette type and preferred e-cigarette flavor (p = .01). Adults smoking non-menthol cigarettes who preferred to use menthol/mint flavored e-cigarettes to quit smoking had longer durations of abstinence compared to those preferring tobacco flavor (LSmean difference = 0.92, CI: 0.39-1.46) or other flavors (LSmean difference = 0.81, CI: 0.15-1.46). Among participants who typically smoked menthol cigarettes, e-cigarette flavor preference was not associated significantly with duration of abstinence (F 3,834 = 1.36, p = 0.25).</p><p><strong>Conclusions: </strong>Menthol/mint e-cigarettes are more often preferred by adults who smoke menthol cigarettes, yet preferring menthol/mint e-cigarettes was associated with longer abstinence durations for those who smoke non-menthol (vs. menthol) cigarettes.</p><p><strong>Implications: </strong>(100 word limit, current This study provides new information about the types of e-cigarette flavors used and preferred by adults who smoke menthol vs. non-menthol cigarettes when using e-cigarettes to try to quit. The association of e-cigarette flavors and abstinence duration varies by cigarette type. While menthol/mint e-cigarette flavors are preferred by adults who smoke menthol cigarettes, menthol/mint e-cigarettes are associated with longer quitting success for those who smoke non-menthol (vs. menthol) cigarettes. More research is needed to understand the impact of e-cigarette flavor by cigarette type. These results may help inform tobacco policy and efforts to maximize reductions in cigarette use.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143582347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chris J Kennedy, Bhavin Gajjar, Ho-Chun Herbert Chang, Jennifer B Unger, Julia Vassey
{"title":"Demographic trends in e-cigarette social media marketing: perceiving gender presentation and facial age via computer vision.","authors":"Chris J Kennedy, Bhavin Gajjar, Ho-Chun Herbert Chang, Jennifer B Unger, Julia Vassey","doi":"10.1093/ntr/ntaf057","DOIUrl":"https://doi.org/10.1093/ntr/ntaf057","url":null,"abstract":"<p><strong>Introduction: </strong>Demographic characteristics of individuals featured in tobacco promotions, such as gender presentation and perceived age, can influence the impact of tobacco marketing on young people. These characteristics often must be estimated when analyzing social media posts. A novel approach for tobacco control research is to harness computer vision models to identify faces in images or videos and then estimate gender and age presentation based on facial features. Such models could facilitate monitoring trends in the demographics of e-cigarette promoting-content when self-report data are unavailable.</p><p><strong>Methods: </strong>We trained computer vision models to identify faces using the WiderFace dataset (32,203 images), and to estimate gender and age presentation given a detected face using the UTKFace dataset (10,670 images). We then applied our models to a collection of 69,788 Instagram posts from 230 e-cigarette influencers over 2019-2022 to assess temporal trends in demographics.</p><p><strong>Results: </strong>The best performing models were DINO for face detection, ConvNext-v2 for gender presentation (96.7% accuracy), and Eva02 for age estimation (70% accuracy). Analyzing 58,535 detected faces across 98.3% of influencer accounts, we observed a significant shift in the gender distribution of e-cigarette promoting posts on Instagram, with 50% female at the study start (2019) falling to 31% female by the study end (2022). The majority of posts (68%) showed individuals in the 12-24 age range, a stable trend.</p><p><strong>Conclusions: </strong>Computer vision models measured gender and age presentation through facial analysis, enabling scalable demographic trend monitoring of e-cigarette marketing on social media.</p><p><strong>Implications: </strong>Analyzing 69,788 Instagram e-cigarette influencer posts for gender and age presentation using facial recognition algorithms, we detected 58,535 faces and found a trend from equal gender representation in 2019 posts shifting down to 31% female prevalence by 2022. The majority (68%) of posts featured adolescents and young adults of age 12 - 24 and this trend was stable. These findings reinforce the need for expanded theory development of moderation and mediation effects of gendered and age-related tobacco marketing strategies, while highlighting the power of computer vision to scalably monitor real-world tobacco communication and inform regulatory policy.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joon Kyung Nam, James J Yang, Shuyao Ran, Megan E Piper, Anne Buu
{"title":"Bidirectional relationships between sleep quality and nicotine vaping: studying young adult e-cigarette users in real time and real life.","authors":"Joon Kyung Nam, James J Yang, Shuyao Ran, Megan E Piper, Anne Buu","doi":"10.1093/ntr/ntaf056","DOIUrl":"https://doi.org/10.1093/ntr/ntaf056","url":null,"abstract":"<p><strong>Introduction: </strong>It is important to understand the impact of vaping on biological processes such as sleep. To date this has only been examined using cross-sectional, retrospective surveys. This study addresses this knowledge gap by: 1) investigating bidirectional relationships between sleep quality and nicotine vaping based on real-time and real-life data; and 2) exploring how young adults think about sleep and vaping and their reactions to monitoring these constructs.</p><p><strong>Methods: </strong>Thirty-five young adults (ages 18-25) daily e-cigarette users wore smartwatches 24/7 to assess sleep quality and completed ecological momentary assessments for 7 days. Linear mixed models examined (1) whether sleep quality in the prior night predicted vaping frequency, negative mood, and craving today; and (2) whether today's vaping frequency predicted the quality of tonight's sleep. Thematic analysis was conducted on participants' open-ended responses to the follow-up survey to explore what they learned about their sleep and vaping through self-monitoring.</p><p><strong>Results: </strong>A higher percentage of wake time after sleep onset predicted higher levels of negative mood (β=3.9793, p=0.0220) and craving for e-cigarettes (β=3.0806, p=0.0277). Greater vaping frequency predicted lower overall sleep quality (β=-0.2056, p=0.0322) and more time in light sleep (β=0.0011, p=0.0296). The majority of participants reported that during the course of the study they learned that they had sleep problems and vaped more than they thought.</p><p><strong>Conclusions: </strong>The findings of this first real-time and real-life study support bidirectional relationships between sleep quality and nicotine vaping. Smartwatch and smartphone technology to track sleep and vaping influenced self-awareness and shows promise for future vaping cessation interventions.</p><p><strong>Implications: </strong>Limited research has been conducted looking at how vaping can influence sleep and how sleep can influence subsequent vaping among young adults. Data from real-time measures completed in real life showed that vaping interfered with sleep and that waking up more in the middle of the night increased negative affect and craving to vape the following day. Using the smartwatch and app to monitor sleep and vaping increased participants' awareness of these behaviors, which could be used to motivate vaping cessation.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew J Carpenter, Tracy T Smith, Kyle J Walters, Amy E Wahlquist, Katelyn R Koval, Elias M Klemperer
{"title":"Evaluation of Dual Use: Real Time Reductions in Combustible Cigarette Smoking During Co-Occurring Use of E-Cigarettes A Secondary Analysis of a Naturalistic Randomized Clinical Trial.","authors":"Matthew J Carpenter, Tracy T Smith, Kyle J Walters, Amy E Wahlquist, Katelyn R Koval, Elias M Klemperer","doi":"10.1093/ntr/ntaf055","DOIUrl":"https://doi.org/10.1093/ntr/ntaf055","url":null,"abstract":"<p><strong>Introduction: </strong>The pattern and trajectory of dual use are critical to differentiating it as a health benefit vs. harm.</p><p><strong>Methods: </strong>Based within a large, naturalistic randomized controlled trial of e-cigarette in the U.S., adults who smoke were given a 1-month sample of tank-style e-cigarette to use as they wish (n=427) or not (n=211). Analyses are restricted to participants from the e-cigarette group who became dual users by one month (DU; n=315) vs. participants in control group who exclusively used combustible cigarettes (EUCC; n=182). Primary outcomes are based on changes in combustible cigarette smoking (cigarettes per day; CPD) across daily diaries within sampling period, and at 3 and 6-month follow-up.</p><p><strong>Results: </strong>DUs reported significantly more diary days of large smoking reduction (smoking 1-50% of baseline CPD: 23.1% of all diary days) and not smoking (5.6% of all diary days) than did EUCCs (6.8% and 1.4%, respectively) during sampling period (p's < .001). Among DUs, 18.4% reported smoking 1-50% of baseline CPD and 9.5% were not smoking at Week 12; 17.5% reported smoking 1-50% of baseline CPD and 9.2% were not smoking at Week 24. In contrast, among EUCCs, 7.1% reported 1-50% of baseline CPD at Week 12 and 1.7% were not smoking. At Week 24, 8.2% reported 1-50% of baseline CPD and 7.1% were not smoking. Among DUs, e-cigarette use days were associated with greater probability of non-smoking days (8%) than non-e-cigarette use days (3%, p <.001).</p><p><strong>Conclusion: </strong>Compared to continued cigarette smoking, initiating dual use reduced smoking and increased cigarette-free days.</p><p><strong>Implications: </strong>Contrary to some claims that dual use of combustible and e-cigarettes may perpetuate or even increase harmful exposure, evidence from the current analyses, collected in real time as dual use unfolds, suggest that dual use leads to significant and sustained reductions in cigarette smoking.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rime Jebai, Sarah D Kowitt, Leah M Ranney, Jennifer Cornacchione Ross
{"title":"Psychological Distress is Associated with Blunt Use Among Youth in the US: Insights from the 2021-2023 National Youth Tobacco Surveys.","authors":"Rime Jebai, Sarah D Kowitt, Leah M Ranney, Jennifer Cornacchione Ross","doi":"10.1093/ntr/ntaf049","DOIUrl":"https://doi.org/10.1093/ntr/ntaf049","url":null,"abstract":"<p><strong>Introduction: </strong>Blunts (hollowed-out cigars filled or mixed with cannabis) are popular among youth. Research on psychological distress and other determinants of blunt use is scant. This study examined factors associated with blunt use among a nationally representative sample of US youth.</p><p><strong>Methods: </strong>Data were from the 2021-2023 (n=68,253) cross-sectional National Youth Tobacco Surveys. Anxiety and depression were assessed using the Generalized Anxiety Disorder scale and the Patient Health Questionnaire, dichotomized into yes/no categories. Youth reporting blunt use at least once in their lifetime were classified as having ever used blunts. To estimate the association between anxiety, depression, race, sexual orientation, and ever blunt use, we conducted weighted logistic regressions for middle and high school students, adjusted for demographics.</p><p><strong>Results: </strong>The prevalence of ever blunt use increased from 7.5% to 7.7% from 2021 to 2022, then decreased to 6.6% in 2023. High school students identifying as bisexual [1.26, (1.04,1.52)] (vs. straight) had higher odds of ever blunt use. Hispanic [1.21, (1.00,1.45)] and non-Hispanic Black high school students [1.59, (1.27, 2.00)] (vs. non-Hispanic White youth) were more likely to report ever blunt use. High school students with anxiety [1.29, (1.11,1.50)] and depression [1.38, (1.18, 1.60)] had higher odds of ever blunt use compared to youth without these conditions. Similar results were observed for middle school students.</p><p><strong>Conclusions: </strong>Middle and high school students who reported psychological distress, or identified as bisexual, Hispanic, or non-Hispanic Black were more likely to report ever blunt use. Findings underscore the importance of cannabis use control efforts designed to reach minoritized communities and those with psychological distress.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samantha G Farris, Andrew H Rogers, Angelo M DiBello, Brianna R Altman, Jacqueline E Smith-Caswell, Geralyn Lambert-Messerlian, Michael E Saladin, Ana M Abrantes
{"title":"The Influence of Perimenstrual Daily Ovarian Hormones on Anxiety and Cigarette Craving.","authors":"Samantha G Farris, Andrew H Rogers, Angelo M DiBello, Brianna R Altman, Jacqueline E Smith-Caswell, Geralyn Lambert-Messerlian, Michael E Saladin, Ana M Abrantes","doi":"10.1093/ntr/ntaf052","DOIUrl":"https://doi.org/10.1093/ntr/ntaf052","url":null,"abstract":"<p><strong>Introduction: </strong>Estradiol (E2) and progesterone (P) and their fluctuation during the female menstrual cycle have been independently linked to both nicotine reinforcement and anxiety. The fluctuation and withdrawal of E2 and P during perimenstrum (days before and during menses) is a vulnerability window for emotional distress, thus the hormonal influence on anxiety and craving may be amplified during perimenstrum.</p><p><strong>Method: </strong>Naturalistic daily data were collected from non-treatment-seeking females who endorsed daily cigarette smoking (N=50). The daily protocol involved morning salivary index of E2 and P and ecological momentary assessments of anxiety and cigarette craving. Days of the menstrual cycle were coded as either occurring during perimenstrum (i.e., seven days prior to and first three days after menstrual onset) or reference (i.e., all other times during cycle). Using multilevel modeling, we tested the main and interactive effects of daily E2, P, and perimenstrum (yes/no) on same-day anxiety and cigarette craving.</p><p><strong>Results: </strong>Results indicated significant three-way interactions between E2 and P both centered between and within perimenstrum for anxiety and craving. In perimenstrum, anxiety and craving were elevated regardless of hormonal balance. However, the association between P and anxiety varied in the context of E2, such that higher P and lower E2 dampened anxiety outside of perimenstrum. Similarly, higher P and lower E2 was associated with lower craving outside perimenstrum.</p><p><strong>Discussion: </strong>These data provide high specificity for understanding hormonal influences on anxiety and craving during the menstrual cycle, which has implications for female-specific models and treatment of the anxiety-smoking comorbidity.</p><p><strong>Implications: </strong>This is the first study to document daily-level associations between salivary estradiol and progesterone, and their interaction, with anxiety and cigarette craving, in the context of the female menstrual cycle. Perimenstrum (i.e., days before and during menses) appears to confer risk for anxiety and craving regardless of the hormonal balance. However, higher daily P dampened anxiety but only in the context of lower daily E2 on days outside of perimenstrum. For craving, higher P with lower E2 was associated with lower craving outside of perimenstrum. The ovarian hormonal milieu should be considered when understanding the etiology and subsequent treatment of anxiety-smoking comorbidity in females.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kristin J Perry, Miglena Y Ivanova, Muntasir Masum, Danny Rahal, Veronica L Richards, Josephine T Hinds
{"title":"Heterogeneity in Protective Factors as a Buffer for Unique Risk Factors and Daily Smoking among Transgender Adults.","authors":"Kristin J Perry, Miglena Y Ivanova, Muntasir Masum, Danny Rahal, Veronica L Richards, Josephine T Hinds","doi":"10.1093/ntr/ntaf051","DOIUrl":"https://doi.org/10.1093/ntr/ntaf051","url":null,"abstract":"<p><strong>Introduction: </strong>Transgender individuals often face significant interpersonal and systemic gender identity-related stressors, which can confer risk of poor health behaviors, including cigarette use. Despite these adversities, social factors (e.g., family acceptance and work support) and gender identity milestones (e.g., affirming medical care) can buffer against stressors. Because transgender individuals live under different circumstances from one another, protective factors vary among individuals. We aimed to derive distinct classes of protective factors and explore whether the associations between gender identity-based stressors and combustible cigarette use varied across these classes.</p><p><strong>Methods: </strong>We analyzed data from the National Transgender Discrimination Survey (N = 6,456; 76.0% white; 46.5% feminine/transfeminine).</p><p><strong>Results: </strong>Using latent class analysis, we identified five classes of gender identity-related protective factors. Class membership moderated associations between stressors and smoking. Interpersonal gender identity-based stressors were associated with greater odds of daily smoking relative to never smoked status for all classes, except for a class characterized by not living congruently with gender identity but having family support and correct IDs. State inequality was associated with higher odds of daily cigarette smoking relative to never smoked for the class living congruently with their gender identity who had not undergone surgery.</p><p><strong>Conclusions: </strong>These findings highlight the complexity of protective factor constellations and their differential protective impact on smoking risk. Prevention efforts should recognize that social factors and gender identity milestones are unevenly distributed and cultivate factors that are congruent with an individual's gender identity.</p><p><strong>Implications: </strong>Transgender adults remain at higher risk for cigarette use than cisgender adults, a salient health disparity for this community. This study helps elucidate the complex interplay between protective factors and identity-based stressors in predicting cigarette smoking among transgender adults. Results demonstrated that interpersonal and systemic gender identity-based stressors were associated with more frequent cigarette smoking. Furthermore, there was substantial heterogeneity in protective factors transgender adults experience, underscoring the need for individualized, context-specific approaches to prevention and intervention efforts to address cigarette smoking within this community.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sharon Cox, Sarah E Jackson, Jamie Brown, Dimitra Kale, Lion Shahab
{"title":"Trends in single and multiple non-combustible nicotine product use: a population study in England.","authors":"Sharon Cox, Sarah E Jackson, Jamie Brown, Dimitra Kale, Lion Shahab","doi":"10.1093/ntr/ntaf048","DOIUrl":"https://doi.org/10.1093/ntr/ntaf048","url":null,"abstract":"<p><strong>Introduction: </strong>Non-combustible nicotine products are commonly used and are used alone or in combination. This study aimed to provide up-to-date estimates of the prevalence of single and multiple non-combustible nicotine product use among adults in England in 2023 and to estimate trends between 2013 and 2023.</p><p><strong>Methods: </strong>Data were drawn from repeated cross-sectional surveys of adults (≥18y) in England conducted between January 2013 and December 2023. Single non-combustible nicotine product use was defined as current use of one of: nicotine replacement therapy (NRT), e-cigarettes, nicotine pouches, or heated tobacco products. Multiple use was defined as current use of two or more of these products. We used logistic regression to estimate monthly time trends in the prevalence of single and multiple product use across the study period and provided descriptive data by smoking status and sociodemographic characteristics.</p><p><strong>Results: </strong>The proportion of adults using any single non-combustible nicotine product increased non-linearly from 5.4% (95%CI=5.1-5.9) in January 2013 to 14.3% (13.6-15.0) in December 2023. The prevalence of multiple non-combustible nicotine product use was 0.7% (95% CI 0.6-0.9) in January 2013 and stable until 2020 before increasing to 1.4% by December 2023 (95% CI 1.2-1.7). Most single and multiple non-combustible nicotine product users were individuals who currently (44.7% [43.1-47.6] and 70.6% [64.2-76.1], respectively) or had formerly smoked (41.2% [39.1-43.4 and 25.5% [19.4-31.5).</p><p><strong>Conclusion: </strong>Use of non-combustible nicotine products has increased substantially among adults in England over the past decade. While most use only one product, a growing minority (predominantly individuals who currently smoke) use multiple non-combustible nicotine products.</p><p><strong>Implications: </strong>Over recent years, the proportion of adults in England reporting single and multiple non-combustible nicotine product use has risen, with the prevalence of single product use almost tripling and multiple product use doubling. It will be important to continue monitoring product use patterns as the market continues to evolve rapidly. There is also a need for further research to understand how different patterns of non-combustible nicotine use may affect people's motivation to stop smoking or success in quitting.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}