Nicotine & Tobacco Research最新文献

{"title":"Biomarkers of Exposure to Tobacco-Related Toxicants among Adult Nicotine Pouch Users.","authors":"Hongying Daisy Dai, Brian Young","doi":"10.1093/ntr/ntaf185","DOIUrl":"https://doi.org/10.1093/ntr/ntaf185","url":null,"abstract":"<p><strong>Introduction: </strong>Nicotine pouches (NPs) are an emerging nicotine delivery system. Understanding nicotine and toxicant exposure among NP users compared with users of other tobacco products and non-users is critical for informing public health strategies.</p><p><strong>Methods: </strong>Data (n = 4527) were drawn from the Population Assessment of Tobacco and Health Study Wave 7 (2022-2023). Participants were classified into four mutually exclusive groups: non- tobacco users, exclusive NP users, exclusive e-cigarette users, and exclusive cigarette smokers. Geometric mean concentrations of biomarkers from urinary nicotine metabolites, minor tobacco alkaloids, and heavy metals were compared across groups using general linear model adjusted for demographics and current marijuana use.</p><p><strong>Results: </strong>Despite having higher levels of nicotine metabolites than non-tobacco users (e.g., cotinine, 2137.2 vs. 0.2 ng/mg creatinine, p<.0001), exclusive NP users showed no significant differences in levels of metals or minor tobacco alkaloids (p>.05). Exclusive NP users had comparable levels of nicotine metabolites to exclusive cigarette smokers (p>.05), but significantly higher concentrations of certain nicotine metabolites than exclusive e-cigarette users (e.g., TNE-2: 27.3 vs. 7.0, p=.02). Meanwhile, exclusive NP users exhibited lower levels of anabasine (0.6 vs. 9.3 ng/mg creatinine, p<.0001), anatabine (0.4 vs. 14.7 ng/mg creatinine, p<.0001), and lead (0.2 vs. 0.4 ng/mg creatinine, p=.003) than exclusive cigarette smokers and lower levels of lead (p=.02) than exclusive e-cigarette users.</p><p><strong>Conclusions: </strong>NP users have substantially elevated nicotine exposure without a corresponding rise in selected tobacco alkaloids or metals. Findings from objective biomarker measures could inform harm reduction strategies and shape regulatory policies concerning emerging nicotine products.</p><p><strong>Implications: </strong>Nicotine pouches are gaining popularity in the United States. The long-term health effects of nicotine pouch use remain unknown, and this national study offered early evidence into the scope of toxicant exposure associated with nicotine pouch use. Exclusive nicotine pouch users exhibited higher levels of nicotine metabolites but lower concentrations of anabasine and lead compared to cigarette smokers, indicating that nicotine pouches may serve as a potential harm-reduction strategy for combustible cigarette smokers. Findings from this study add to the current field of tobacco regulatory science and may inform future efforts to evaluate their effectiveness in smoking cessation or substitution.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of state-level flavored electronic cigarette restrictions on adult tobacco use using multilevel modeling: Findings from the PATH Study Waves 5 & 7 (2018-2023).","authors":"John H Kingsbury, Michael J Parks, Heather Kimmel, Eiman Aboaziza, Carlos Blanco, Wilson Compton","doi":"10.1093/ntr/ntaf187","DOIUrl":"https://doi.org/10.1093/ntr/ntaf187","url":null,"abstract":"<p><strong>Introduction: </strong>Flavors play an important role in e-cigarette use among both young people and adults, but evaluations of flavored e-cigarette policies have focused almost exclusively on youth. This longitudinal study examined how flavored e-cigarette policies affect tobacco use over time for different adult age groups using data from the Population Assessment of Tobacco and Health (PATH) Study.</p><p><strong>Methods: </strong>Adults age 21+ at Wave 5 (2018-2019) comprised the analytic sample. Multilevel models were used to examine changes in past 30-day and established e-cigarette use, and past 30-day tobacco use other than e-cigarettes at Wave 7 (2022-2023) for residents of states that had (vs. had not) implemented flavored e-cigarette policies between Waves 5 and 7. Sociodemographic variables and state-level tobacco control policies (e.g., e-cigarette tax, clean indoor air) were controlled. Regression models tested effects overall and by age group: 21-24, 25-29, 30-39, 40+. Full-sample and replicate weights accounted for the complex sample design and nonresponse.</p><p><strong>Results: </strong>Among those exposed to a flavored e-cigarette policy, there was a significant decrease in odds of past 30-day e-cigarette use for those age 21-24 (AOR=0.59; 95%CI: 0.36, 0.97) and in odds of established e-cigarette use for those age 25-29 (AOR=0.32; 95%CI: 0.14, 0.76) compared to those who were unexposed, adjusting for covariates. There was no change in use of tobacco products other than e-cigarettes by flavored policy exposure.</p><p><strong>Conclusion: </strong>Flavored e-cigarette policies are effective at reducing past 30-day and established e-cigarette use among younger adults (age 21-29). The impact among older adults (30+) is less evident.</p><p><strong>Implications: </strong>Using longitudinal data and multilevel models, this study demonstrates how flavored e-cigarette policies influence e-cigarette use (and other tobacco product use) for younger adults (21-29). We find limited evidence of policies influencing older adults (30+). This work suggests that flavored e-cigarette policies may play an important role in stopping young people from initiating e-cigarette use, and in stopping older young adults (age 25-29) from progressing to more established e-cigarette use.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying latent classes of dual cigarette/ENDS users based on motivations for ENDS use: Product substitution versus complementary use.","authors":"Lauren R Pacek, Ollie Ganz, Dana Rubenstein, Patrick V Barnwell, F Joseph McClernon","doi":"10.1093/ntr/ntaf188","DOIUrl":"https://doi.org/10.1093/ntr/ntaf188","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study was to empirically identify subgroups of dual cigarette and ENDS product users based on their motivations for ENDS use.</p><p><strong>Methods: </strong>Data came from n=713 adult dual cigarette/ENDS users in the Population Assessment of Tobacco and Health Wave 6 public use data file. We used latent class analysis to identify qualitatively different subgroups within the sample and applied logistic regression to assess correlates of latent class membership.</p><p><strong>Results: </strong>We identified two latent classes: \"Substituters\" (62.81%) and Complementers (37.19%). Classes were primarily distinguished by Substituters reporting a higher probability of using ENDS to cut down on (97.99%) or quit (86.12%) cigarette smoking; the converse was true for Substituters (16.95%; 3.17%, respectively). Compared to Substituters, Complementers (aOR=0.87, 95% CI=0.81-0.96) expressed less interest in smoking cessation. Moreover, Complementers were less likely to have made a past-year smoking quit attempt (aOR=0.46, 95% CI=0.27-0.77) and more likely to smoke the same number of cigarettes as usual (aOR=3.62, 95% CI=2.04-6.42) or more cigarettes than usual (aOR=5.96, 95% CI=1.92-18.51) on days when they both smoked and vaped than were Substituters. No sociodemographic differences were observed.</p><p><strong>Conclusions: </strong>We identified distinct latent classes of dual cigarette/ENDS users, predominantly differentiated based on their reported probabilities of using ENDS to assist in quitting or cutting down on cigarette smoking. Findings that class membership is associated with interest in quitting and quit attempts have significant health, treatment, and study design implications.</p><p><strong>Implications: </strong>The identification of distinct classes of dual cigarette/ENDS users based on their motivations for ENDS use and differential associations between class membership and tobacco use characteristics has a number of implications. Class membership may affect cessation treatment approaches and has significant implications for scientific study design.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring compliance with the ban on tobacco advertising, promotion and product display at the point-of-sale 10 months after its implementation in Dakar, Senegal.","authors":"Ernesto Marcelo Sebrie, Mamadou Bamba Sagna, Kai Wasson, Caroline Fuss, Mary Clare Rosemeyer, Oumar Ba, Bintou Camara Bityeki","doi":"10.1093/ntr/ntaf183","DOIUrl":"https://doi.org/10.1093/ntr/ntaf183","url":null,"abstract":"<p><strong>Introduction: </strong>In 2014, Senegal emerged as a leader in tobacco control in the WHO African Region (AFRO) after adopting one of the strongest national tobacco control laws in AFRO. Among other measures, the law included a comprehensive ban on tobacco advertising, promotion, and sponsorship (TAPS) at the point-of-sale (POS), including a ban on product display. The goal of this study was to assess retailer compliance with the TAPS ban in Dakar, Senegal, 10 months after its implementation at the POS.</p><p><strong>Methods: </strong>Using a purposive sampling strategy, retail audits were performed at 309 tobacco retailers in 12 neighborhoods of Dakar. Data collectors used Kobo Toolbox, a web-based data collection platform. A checklist was developed based on the TAPS provisions, Euromonitor data, and a previous compliance packaging and labeling study conducted in Dakar. The survey included neighborhood name and location, hub location, POS type, tobacco products for sale, and type of tobacco advertising, promotion, and product displays observed.</p><p><strong>Results: </strong>Overall compliance with the ban on all TAPS at the POS was observed at less than 5% (n = 15) of stores surveyed and varied by retailer type. Compliance with the ban on product display was 6.1% (n = 19), while compliance with all other components of the TAPS ban combined was higher, at 67.3% (n = 208). Philip Morris International and Imperial Tobacco products and marketing were responsible for most violations observed.</p><p><strong>Conclusions: </strong>Low levels of compliance 10 months after implementation may suggest weak enforcement from local authorities and intentional undermining of advertising bans from the tobacco industry.</p><p><strong>Implications: </strong>Exposure to TAPS at the POS increases impulse buying, normalizes tobacco products and use, and increases likelihood of youth initiation. There is a dearth of implementation literature for tobacco control policies in the WHO African Region. This study provides monitoring and compliance data in Dakar, Senegal 10 months after implementation of a national TAPS ban. This study presents data for policymakers in Senegal and similar low- and middle-income settings on specific areas of a tobacco control law that may require additional enforcement measures for better compliance.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efforts to secure nicotine and cannabis product placements in popular media by Ploom, Pax, and Juul: an analysis of tobacco industry documents.","authors":"Tanner Wakefield, Stella Bialous, Pamela Ling, Dorie E Apollonio","doi":"10.1093/ntr/ntaf180","DOIUrl":"10.1093/ntr/ntaf180","url":null,"abstract":"<p><strong>Introduction: </strong>Tobacco companies advertised cigarettes in popular media to increase social acceptability. Most research on e-cigarette product placement has been content analyses of music videos. We explored the motivations, activities, and results of product placement activities of the e-cigarette company Ploom and its successors, Pax Labs and Juul Labs, in music videos as well as film and television.</p><p><strong>Methods: </strong>Case study using internal industry documents released in litigation and housed at the UCSF Truth Tobacco Industry Documents Library. Relevant documents were cataloged, summarized, and placed in chronological order.</p><p><strong>Results: </strong>We identified 451 relevant documents. Ploom sought product placements to expand its audience and enhance credibility. After Ploom split into Pax Labs and Juul Labs, they pursued free product placements by establishing relationships with prop masters in the entertainment industry and loaning devices to media productions using a placement agency. Later, Pax devices secured placements in music videos, film, and television; Juul appeared to secure only one placement.</p><p><strong>Conclusions: </strong>Ploom and its successor companies secured free product placements in music videos, films, and television. Pax devices associated with cannabis were placed more frequently than Juul. Given that tobacco advertising causes youth initiation, stronger regulation of product placement practices may be warranted.</p><p><strong>Implications: </strong>Ploom, Pax Labs, and Juul Labs used entertainment industry firms and outreach to prop masters to obtain free numerous product placements as consumers in general increasingly ignore or avoid traditional advertising. Product placements, which can improve brand recall, are better liked than commercials, and contribute to youth smoking uptake, appeared in popular and culturally relevant movies, shows, and music videos. E-cigarette industry product placement practices reflected those successfully used by major tobacco companies in the past.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What tranSPIREs from recent research on e-cigarettes? Towards a comprehensive approach to model vaping policies.","authors":"Lion Shahab, Hazel Squires","doi":"10.1093/ntr/ntaf184","DOIUrl":"https://doi.org/10.1093/ntr/ntaf184","url":null,"abstract":"","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of NFL-101 as a Smoking Cessation Therapy: A Randomized Phase II Clinical Trial CESTO2.","authors":"Claire Lafay-Chebassier, Pierre-Olivier Girodet, Fabrice Laine, Jean-Sébastien Allain, Gisele Pickering, Mathilde Latreille, Anastasia Demina, Hugues Chevassus, Isabelle Ingrand, Eric Tartour, Nadine Benhamouda, Marie-Laure Fraisse, Liliya Chamitava, Yannick Plétan, Julie Balland, Yves Donazzolo, Bruno Lafont","doi":"10.1093/ntr/ntaf181","DOIUrl":"https://doi.org/10.1093/ntr/ntaf181","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Tobacco addiction remains a major public health challenge. Existing smoking cessation treatments require prolonged daily use with potentially poor adherence and reduced efficacy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The phase II study was a multicenter, randomized, double-blind, placebo-controlled trial with a one-year follow-up to assess the efficacy, safety, and immunogenicity of NFL-101 as a potential aid for smoking cessation. 318 adult daily smokers were randomized to receive subcutaneous injections of NFL-101-100 μg, NFL-101-200 μg or placebo on Day1 and Day8. The primary outcome was 6-week post-quit 28-day continuous abstinence (CA, Day15-Day43), validated by exhaled CO.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;CO verified 6-week post-quit CA was: NFL-101-100 μg: 31/108(28.7%), 200 μg: 23/109(21.1%), and placebo: 18/101(17.8%). NFL-101-100 μg vs placebo, RR = 1.61, p=.063, and 200 μg vs placebo RR = 1.18, p=.5492). CA, when urinary cotinine was used, was: 26/108(24.1%) for NFL-101-100 μg, 18/109(16.5%) for 200 μg and 13/101(12.9%) for placebo. NFL-101-100 μg vs placebo showed an RR = 1.87, 95%CI:1.02-3.44, p=.0378 and 200 μg vs placebo was RR = 1.28, 95%CI:0.66-2.48, p=.4572. If individuals who used NRTs/e-cigarettes were classified as non-abstinent, then 29/108(26.9%) were abstainers for NFL-101-100 μg and 14/101(13.9%) for placebo (p=.0203). NFL-101-100 μg RR remained stable between 28-day and 12-month. At Day43, NFL-101-100 μg reduced craving (p&lt;.05), with no significant difference for withdrawal symptoms. Abstainers experienced greater increases in anti-NFL-101-IgG concentrations compared to nonabstainers (p&lt;.009). NFL-101 was well-tolerated.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Although the pre-specified primary endpoint was not statistically significant, if the primary outcome had been defined as nicotine abstinence, the results would have reached statistical significance. Efficacy, craving reduction and minimal dosing regimen of NFL-101-100 μg support its potential as a promising smoking cessation therapy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Implications: &lt;/strong&gt;In this multicenter randomized clinical trial that included 318 smokers, effect sizes between groups were sufficiently large to suggest a meaningful clinical effect. NFL-101 at a dose of 100 μg increased 6-week post-quit 28-day continuous smoking abstinence that was confirmed by urinary cotinine concentrations and reduced craving, suggesting psychological benefits that could mitigate relapse risks. Abstainers experienced a significant increase in anti-NFL-101 IgG concentrations compared to those who continued to smoke.Findings from the present study offer support for an entirely new category of treatment that acts through immune modulation. Additional strengths include a subcutaneous route of administration in the form of two injections spaced a week apart (thus, enhances treatment adherence) and has demonstrated a safe profile with minimal adverse effects. These results supp","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secondhand E-cigarette and Tobacco Smoke Exposure and Stages of E-cigarette Use in U.S 6th-12th Graders.","authors":"Stephen Freeman, Mara B O'Connor, Amanda R Mathew, Brian Hitsman","doi":"10.1093/ntr/ntaf179","DOIUrl":"https://doi.org/10.1093/ntr/ntaf179","url":null,"abstract":"<p><strong>Introduction: </strong>Studies examining the association of secondhand exposures with e-cigarette use behaviors have been limited by indirect or incomplete measures of exposure. This study reports the prevalence of secondhand e-cigarette and tobacco smoke exposure among U.S youth and examines how robust measures of secondhand exposure correlate with e-cigarette susceptibility, ever use, daily use, and quit attempts.</p><p><strong>Methods: </strong>A cross-sectional analysis of 21,946 U.S. 6th-12th graders from the 2023 National Youth Tobacco Survey was conducted. Participants' past 30-day secondhand exposure status was classified as: no secondhand exposure, secondhand e-cigarette only, secondhand tobacco smoke only, or dual secondhand exposure. Multivariate, weighted logistic regression evaluated secondhand exposure status as a predictor of four binary e-cigarette use outcomes in separate models: susceptibility, ever use, daily use, and past 12-month serious quit attempt.</p><p><strong>Results: </strong>The estimated prevalence of past 30-day secondhand e-cigarette or tobacco smoke exposure was 64.2% (18.18 million). Secondhand exposure to e-cigarettes (AOR 2.14 95% CI [1.54-2.98]), tobacco smoke (AOR 1.62 [1.32-2.00]), and dual exposure (AOR 2.44 [2.10-2.84]) were each associated with greater e-cigarette susceptibility. Secondhand e-cigarette (AOR: 2.45 [1.69-3.56]) and dual exposure (AOR: 1.55 [1.23-1.94]), but not secondhand tobacco smoke exposure, were positively associated with e-cigarette ever use. There were no significant associations between secondhand exposure and daily e-cigarette use or serious quit attempts.</p><p><strong>Conclusions: </strong>Secondhand e-cigarette and tobacco smoke exposure remains highly prevalent among U.S 6th-12th graders and is strongly associated with early stages of e-cigarette use, but not later stages. Minimizing youth secondhand exposure could have important public health benefits.</p><p><strong>Implications: </strong>This study uses the latest data from the 2023 National Youth Tobacco Survey to highlight how the prevalence of secondhand e-cigarette and tobacco exposure among U.S 6-12 graders remains quite high (64.2%, 18.18 million) despite decreases in youth tobacco and e-cigarette use since 2019. Further, unlike prior studies limited to examining a single stage of e-cigarette use, this study examines how robust measures of secondhand exposure correlate with outcomes spanning the stages of e-cigarette use: susceptibility, ever use, daily use, and quit attempts. Ultimately, it reinforces secondhand exposure among U.S youth as an important and timely public health challenge.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Title: Designing Religiously Informed and Culturally Acceptable Tobacco Cessation Interventions for UK-Based Muslims.","authors":"Felix Naughton, Sylvia Barnes, Carole Gardener, Caitlin Notley, Rachna Begh, Nicola Lindson, Salman Waqar, Chloë Siegele-Brown, Aimie Hope","doi":"10.1093/ntr/ntaf178","DOIUrl":"https://doi.org/10.1093/ntr/ntaf178","url":null,"abstract":"<p><strong>Introduction: </strong>Globally, tobacco use rates in Muslim communities, particularly among men, are significantly higher than in non-Muslim communities. In the UK, there are also low rates of help seeking among British Muslims who use tobacco. Ramadan could be a \"window of opportunity\" to support tobacco use behavior change but we lack the voice of British Muslim communities on culturally tailored cessation support. We undertook a public and patient involvement and engagement (PPIE) project to gain views from representatives of these communities.</p><p><strong>Methods: </strong>Discussions with fifteen PPIE representatives from, or who worked with, a variety of British Muslim communities identified through gatekeepers, social media and snowballing approaches. Key points and views from PPIE discussions were summarized into broad themes.</p><p><strong>Results: </strong>Opportunities and challenges with culturally adapting tobacco cessation support to Ramadan were raised. \"Light touch\" positive religious messaging connected to tobacco cessation was recommended, and over-emphasizing religion in messaging content to be avoided. Quitting during Ramadan was felt challenging due to fasting, precluding the use of nicotine replacement products or medication, and reinforcing tobacco use as part of fast-breaking routines. Instead, PPIE representatives suggested quitting in advance of Ramadan or promoting cessation afterwards by capitalizing on tobacco reduction achieved during Ramadan. There was support for digital cessation approaches, but it was felt many in their communities would prefer traditional approaches, including interpersonal support and messaging through influential community members.</p><p><strong>Conclusions: </strong>\"Light touch\" culturally tailored tobacco cessation support before or after Ramadan was felt more promising than supporting cessation initiation during Ramadan.</p><p><strong>Implications: </strong>Members of British Muslim communities identified challenges with using Ramadan as a \"window of opportunity\" for tobacco behavior change and favored quitting ahead of time for Ramadan or capitalizing on tobacco behavior change achieved during Ramadan to promote a quit attempt afterwards. Taking a \"light touch\" approach with religiously tailored messaging could help engage Muslim people who smoke in cessation support. However, avoiding any strong or negatively framed tobacco-related messages linked to religious phrases or imagery is important. This work reinforces the importance of engaging with communities when considering culturally adapting interventions to prevent misdirected adaptions.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"E-cigarette use at the intersection of sexual identity and race/ethnicity among US adults: Results from 2021-2023 National Health Interview Survey (NHIS).","authors":"Juhan Lee, Andy S L Tan","doi":"10.1093/ntr/ntaf176","DOIUrl":"https://doi.org/10.1093/ntr/ntaf176","url":null,"abstract":"<p><strong>Introduction: </strong>Understanding e-cigarette use among those with multiple intersecting marginalized identities is important since those individuals might experience intersectional minority stress, which is associated with tobacco use. This study examined the prevalence of e-cigarette use at the intersection of race/ethnicity and sexual identity among US adults.</p><p><strong>Methods: </strong>We analyzed the pooled 2021 to 2023 National Health Interview Survey (NHIS) dataset adult samples (N=86655). We conducted an adjusted binomial logistic regression analysis to predict past-30-day e-cigarette use with sexual identity (straight, gay/lesbian/bisexual/something else [LGB+]), race/ethnicity (Non-Hispanic White, Non-Hispanic Black/African American, Non-Hispanic Asian, Non-Hispanic American Indian and Alaska Native, Hispanic, Other races) and an interaction term between sexual identity and race/ethnicity in one model, adjusted for age, education, cigarette smoking, and diagnoses of chronic diseases. The results were stratified by sex and the adjusted predicted margins were estimated.</p><p><strong>Results: </strong>Among total respondents, 5.5% (weighted) reported past-30-day e-cigarette use, 5.3% were LGB+, 11.8% were non-Hispanic Black, 6.1% were non-Hispanic Asian, 1.4% were non-Hispanic American Indian and Alaska Native, and 17.2% were Hispanic. The overall interaction effect between sexual identity and race/ethnicity on outcome was significant among total respondents (p=0.004) and females (p<0.001), but not males. Among females, the adjusted predicted margins for current e-cigarette use between LGB+ individuals and heterosexual individuals in Hispanic groups (4.0% vs. 1.0%) were significantly different from those in the NH White group (4.4% vs. 3.4%).</p><p><strong>Conclusion: </strong>Sexual minority adults in Hispanic groups, particularly Hispanic sexual minority females, may be at increased risk for e-cigarette use than Hispanic heterosexual females.</p><p><strong>Implications: </strong>This study highlights the risk of e-cigarette use among sexual minority adults in non-White racial/ethnic groups, particularly Hispanic sexual minority females. These findings underscore the need for future research to understand the unique drivers of e-cigarette use among Hispanic sexual minority females.</p>","PeriodicalId":19241,"journal":{"name":"Nicotine & Tobacco Research","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}