Neuroreport最新文献_第8页

The effect of referential and emotional information on novel word learning: an fNIRS study. 参考信息和情绪信息对新单词学习的影响：一项fNIRS研究。

IF 1.6 4区医学

Neuroreport Pub Date : 2025-02-05 Epub Date: 2025-01-29 DOI: 10.1097/WNR.0000000000002135

Shan Li, Xue Sui, Yanbo Hu, Yutong Li

{"title":"The effect of referential and emotional information on novel word learning: an fNIRS study.","authors":"Shan Li, Xue Sui, Yanbo Hu, Yutong Li","doi":"10.1097/WNR.0000000000002135","DOIUrl":"10.1097/WNR.0000000000002135","url":null,"abstract":"The current study utilized functional near-infrared spectroscopy to examine the neural mechanisms underlying the effect of referential and emotional information on novel word learning. After learning the meaning of novel words in different sentences, participants were asked to complete a semantic consistency judgment task and a source judgment task. The behavioral data and neural data were recorded simultaneously. The results showed that: (1) referential information affected the novel word learning; (2) the interaction between referential and emotional information was significant; (3) these effects were associated with neural activities in the frontal and temporal lobe, mainly in the activation of the dorsolateral prefrontal cortex, the inferior frontal gyrus, the middle temporal gyrus, the superior temporal gyrus, and the premotor and supplementary motor cortex. The findings suggested that self-referential information could promote the novel word learning. Notably, referential and emotional information jointly affected the novel word learning in the frontal and temporal lobe, indicating the integrative contributions of both referential and emotional information to novel word learning.","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 3","pages":"179-190"},"PeriodicalIF":1.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anxiety-like behaviors in rats exposed to the single and combined program of running exercise and environmental enrichment. 暴露于跑步运动和环境丰富的单一和联合程序的大鼠的焦虑样行为。

IF 1.6 4区医学

Neuroreport Pub Date : 2025-01-08 Epub Date: 2024-12-04 DOI: 10.1097/WNR.0000000000002117

Farnaz Ghayourbabaei, Mohaya Farzin, Zakieh Keshavarzi, Ehsan Saburi, Mohammad Amin Khodadadegan, Vahid Hajali

{"title":"Anxiety-like behaviors in rats exposed to the single and combined program of running exercise and environmental enrichment.","authors":"Farnaz Ghayourbabaei, Mohaya Farzin, Zakieh Keshavarzi, Ehsan Saburi, Mohammad Amin Khodadadegan, Vahid Hajali","doi":"10.1097/WNR.0000000000002117","DOIUrl":"10.1097/WNR.0000000000002117","url":null,"abstract":"Exercise (Ex) and environmental enrichment (EE) as the nondrug solutions have positive effects on cognitive behaviors and also increase the ability to cope with anxiety, fear, and stress. In this research, we decided to investigate the simultaneous effect of Ex and EE on anxiety-like behaviors and hippocampal neurogenesis markers in healthy rats. A total of 40 male Wistar rats were divided into four treatment groups: control, EE, Ex, and EE + Ex. Animals in EE groups were housed in large cages (50 × 50 × 50 cm) equipped with toys and objects of different shapes for 3 weeks. Ex-animals were forced to run on a treadmill once a day for 3 consecutive weeks. Open field (OF) and elevated plus maze (EPM) tests were used to evaluate anxiety behaviors. The hippocampal expression of early neurogenesis markers, doublecortin, and sex determining region Y-box 2, were measured using real-time-PCR. Ex and EE animals separately did not show any significant performance in reducing anxiety levels, neither in EPM nor in OF compared with the control group. When animals were treated with EE and Ex simultaneously, they showed significantly reduced anxiety in both EPM and OF tests compared with the control as well as Ex and EE groups separately. Both treatments in combination were also more effective than individual groups in increasing the neurogenesis molecular markers within the hippocampus. This study proposes that Ex in combination with cognitive engagement is more efficient in alleviating anxiety responses and that can develop a nonpharmacological and multidomain policy that may prevent or delay psychophysiological symptoms.","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 1","pages":"31-38"},"PeriodicalIF":1.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differences in embodied cognition between the arrow-orientation and the arrow-position recognition tasks: evidence from event-related potentials. 箭头方向和箭头位置识别任务的具身认知差异：来自事件相关电位的证据。

IF 1.6 4区医学

Neuroreport Pub Date : 2025-01-08 Epub Date: 2024-12-04 DOI: 10.1097/WNR.0000000000002116

WenJing Qi, Jin Gong, Li Sui

{"title":"Differences in embodied cognition between the arrow-orientation and the arrow-position recognition tasks: evidence from event-related potentials.","authors":"WenJing Qi, Jin Gong, Li Sui","doi":"10.1097/WNR.0000000000002116","DOIUrl":"10.1097/WNR.0000000000002116","url":null,"abstract":"Embodied cognition is known to play a role in verbal semantic processing. However, its involvement in nonverbal semantic elements, such as arrows, is less understood. Two spatial recognition tasks, specifically arrow-orientation recognition and arrow-position recognition, were employed using directional arrows in various spatial arrangements as visual stimuli. Stimuli were categorized into congruent (where orientation and position align), incongruent 1 (where orientation and position are directly opposing), and incongruent 2 (where orientation and position are unrelated) groups for both tasks. To investigate neural processes, event-related potentials (ERPs) were recorded and analyzed during task performance. Additionally, standardized low-resolution electromagnetic tomography (sLORETA) was utilized to examine brain electrical activity during ERP intervals. The analysis revealed significant ERP component differences between congruent and incongruent conditions across both spatial tasks, highlighting a Stroop-like interference effect. Notably, the arrow-orientation task showed marked enhancements in P3 and N400 components, as well as heightened brain activity in the frontal lobe, anterior cingulate cortex, and insula, compared with the arrow-position task. These findings suggest that embodied cognition is involved in both spatial arrow recognition tasks. The unique role of embodied cognition in these contexts is primarily reflected in the modulation of the P3-N400 complex, indicating differentiated cognitive processing.","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 1","pages":"39-46"},"PeriodicalIF":1.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paclitaxel-induced cognitive decline was attenuated by necroptosis inhibition. 紫杉醇诱导的认知能力下降通过抑制坏死性下垂而减轻。

IF 1.6 4区医学

Neuroreport Pub Date : 2025-01-08 Epub Date: 2024-12-04 DOI: 10.1097/WNR.0000000000002121

Lan-Lan Liu, Shuang Zhao, Zhao Li, Hui-Zhou Li, Dong-Yang Ma, Xin Liu, Gui-Ying Wang, Xiu-Li Wang

{"title":"Paclitaxel-induced cognitive decline was attenuated by necroptosis inhibition.","authors":"Lan-Lan Liu, Shuang Zhao, Zhao Li, Hui-Zhou Li, Dong-Yang Ma, Xin Liu, Gui-Ying Wang, Xiu-Li Wang","doi":"10.1097/WNR.0000000000002121","DOIUrl":"10.1097/WNR.0000000000002121","url":null,"abstract":"Anti-cancer agent paclitaxel induces cognitive impairment. Paclitaxel can induce limited neuron apoptosis and wide scope of neuroinflammation, but its precise mechanisms remain unclear. In this study, we determined paclitaxel causes necroptosis, a programmed cell death, via activation of the RIPK1-RIPK3-MLKL signaling pathway in hippocampal neurons (HT22 cells). Flow cytometric analysis, propidium iodide staining, and western blotting techniques were used to evaluate paclitaxel-induced necroptosis. Cell viability was determined using the Cell Counting Kit-8 assay, and the Ca2+ levels were measured using a Fluo-4 AM fluorescent probe. The number of cells positive for both annexin V and propidium iodide staining was significantly higher in paclitaxel-treated than vehicle-treated HT22 cells. Additionally, the nuclei of paclitaxel-treated cells exhibited more diffused necrotic propidium iodide staining than the vehicle-treated cells. The expression of necroptosis-associated proteins, including receptor-interacting protein kinase (RIPK)1, RIPK3, mixed lineage kinase domain-like protein (MLKL), and phosphorylated (p)-MLKL, were increased following paclitaxel treatment. Treating HT22 cells with necrostatin-1, a specific inhibitor for RIPK1, effectively decreased paclitaxel-induced necroptosis through lowering intracellular Ca2+ overload. In addition, administration of necrostatin-1 to paclitaxel-treated mice rescued cognitive impairments, as assessed by novel object recognition and Morris water maze tests. Necrostatin-1 also reduced the increases in necroptosis-associated protein levels of RIPK1, RIPK3, MLKL, and p-MLKL in hippocampal tissue of paclitaxel-treated mice. Paclitaxel induces cognitive deficits through RIPK1-mediated necroptosis. The inhibition of necroptosis may be a potential therapeutic approach to reduce paclitaxel-induced cognitive deficits.","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 1","pages":"61-69"},"PeriodicalIF":1.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic digoxin exposure causes hyperactivity, anxiolysis, and alters brain monoamine content in zebrafish (Danio rerio). 慢性地高辛暴露导致斑马鱼多动、焦虑溶解和改变脑单胺含量（Danio rerio）。

IF 1.6 4区医学

Neuroreport Pub Date : 2025-01-08 Epub Date: 2024-12-04 DOI: 10.1097/WNR.0000000000002120

Rogneda B Kazanskaya, Nikita P Ilyin, Denis A Abaimov, Ksenia A Derzhavina, Konstantin A Demin, Allan V Kalueff, Raul R Gainetdinov, Alexander V Lopachev

{"title":"Chronic digoxin exposure causes hyperactivity, anxiolysis, and alters brain monoamine content in zebrafish (Danio rerio).","authors":"Rogneda B Kazanskaya, Nikita P Ilyin, Denis A Abaimov, Ksenia A Derzhavina, Konstantin A Demin, Allan V Kalueff, Raul R Gainetdinov, Alexander V Lopachev","doi":"10.1097/WNR.0000000000002120","DOIUrl":"10.1097/WNR.0000000000002120","url":null,"abstract":"To investigate the effects of chronic exposure to the cardiotonic steroid digoxin on locomotor activity, anxiety, and brain tissue monoamine content in Zebrafish. In total 24 adult (3-5 months) wild-type experimentally naïve zebrafish (50 : 50 ratio of females to males) were housed in 4-L tanks, in groups of six animals per tank. Two μM Digoxin was maintained in half of the tanks for 7 days. The 'Novel tank test' was performed on day 7 and the animals were euthanized. Concentrations of dopamine, serotonin, and their metabolites were then quantified in brain tissue using HPLC-ED. Seven-day exposure to 2 μM water solution of digoxin caused robust hyperlocomotion and reduced anxiety-like behavior in adult zebrafish in the 'Novel tank test'. The treatment also evoked pronounced neurochemical responses in zebrafish, including increased whole-brain 3-methoxytyramine, reduced norepinephrine and serotonin, and unaltered dopamine, homovanillic acid or 5-hydroxyindoleacetic acid levels. Deficits in monoaminergic (dopaminergic, serotonergic, and noradrenergic) neurotransmission are a key pathogenetic factor for multiple neuropsychiatric and neurodegenerative diseases. Commonly used clinically to treat cardiac conditions, cardiotonic steroids can affect dopaminergic neurotransmission. Chronic exposure to digoxin evokes hyperactivity-like behavior accompanied by altered monoamine neurotransmission in zebrafish, which may be relevant to understanding the central nervous system side effects of cardiotonic steroids.","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 1","pages":"55-60"},"PeriodicalIF":1.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electroacupuncture alleviated chronic cerebral hypoperfusion damages via targeting aquaporin 4 to prevent amyloid-beta accumulation. 电针通过靶向水蒸发蛋白4防止淀粉样蛋白-β积聚减轻慢性脑灌注不足的损害

IF 1.6 4区医学

Neuroreport Pub Date : 2025-01-08 Epub Date: 2024-11-12 DOI: 10.1097/WNR.0000000000002114

Ying Zhang, Lei Wu, Kelin He, Yingying Cheng, Lu Li, Dexiong Han

{"title":"Electroacupuncture alleviated chronic cerebral hypoperfusion damages via targeting aquaporin 4 to prevent amyloid-beta accumulation.","authors":"Ying Zhang, Lei Wu, Kelin He, Yingying Cheng, Lu Li, Dexiong Han","doi":"10.1097/WNR.0000000000002114","DOIUrl":"10.1097/WNR.0000000000002114","url":null,"abstract":"The present study aimed to investigate the therapeutic effects of electroacupuncture (EA) on chronic cerebral hypoperfusion (CCH). We first applied the Morris water maze approach to determine the effects of EA and TGN-020 [an inhibitor of aquaporin 4 (AQP4)] on the learning and memory ability of CCH rats. The hematoxylin and eosin, and Nissl staining were further used to investigate the effects of EA and TGN-020 on the neuropathological changes of the dentate gyrus. Next, the ELISA kits were adopted to determine the effects of EA and TGN-020 on the content of amyloid-beta (Aβ) in the cerebrospinal fluid of CCH rats. Finally, we respectively employed technologies of immunohistochemical staining, quantitative real-time PCR, and Western blot to further explore the effects of EA and TGN-020 on the mRNA expression level of amyloid precursor protein (APP) and AQP4 as well as the protein expression level of Aβ1-42 and AQP4 in the dentate gyrus of CCH rats. Our results indicated that EA not only enhanced the learning and memory abilities of CCH rats but also improved the neuropathological damages of CCH rats by upregulating the mRNA and protein expression level of AQP4 to reduce the accumulation of Aβ, especially for the reduction of the mRNA expression level of APP and the protein expression level of Aβ1-42, but TGN-020 effectively reversed the therapeutic effects mentioned above of EA. In summary, we proved that EA, as the activator of AQP4, prevents the accumulation of Aβ during the treatment of CCH.","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":" ","pages":"11-21"},"PeriodicalIF":1.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142624955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electroacupuncture alleviates cerebral ischemia injury by regulating PI3K/AKT/NF-κB signaling in microglia of ischemic stroke rats. 电针通过调节缺血性脑卒中大鼠小胶质细胞PI3K/AKT/NF-κB信号通路减轻脑缺血损伤。

IF 1.6 4区医学

Neuroreport Pub Date : 2025-01-08 Epub Date: 2024-12-04 DOI: 10.1097/WNR.0000000000002115

Rao Rao, Lingling Gan, Rui Zhao, Yongsheng Han

{"title":"Electroacupuncture alleviates cerebral ischemia injury by regulating PI3K/AKT/NF-κB signaling in microglia of ischemic stroke rats.","authors":"Rao Rao, Lingling Gan, Rui Zhao, Yongsheng Han","doi":"10.1097/WNR.0000000000002115","DOIUrl":"10.1097/WNR.0000000000002115","url":null,"abstract":"This study aimed to investigate the potential of electroacupuncture as an intervention for inducing 'Awakening and Opening of the Brain' in rats with stroke models induced by middle cerebral artery occlusion/reperfusion (MCAO/R). The efficacy of electroacupuncture in alleviating cerebral ischemic injury was evaluated using Longa scores, triphenyl tetrazolium chloride staining, and hematoxylin and eosin staining. Non-targeted metabolomics analysis was conducted to identify differential metabolite changes before and after electroacupuncture treatment in MCAO/R rats. Network pharmacology analysis was then performed to correlate these differential metabolites with ischemic stroke. The PI3K/AKT/NF-κB signaling pathway was identified as a key target. In vivo experiments further validated the mechanism by which electroacupuncture promotes M2 microglial polarization through inhibition of the PI3K/AKT/NF-κB signaling in MCAO/R rats. This study demonstrated that electroacupuncture reduces brain damage and inhibits inflammation in MCAO/R rats by modulating the PI3K/AKT/NF-κB signaling pathway and promoting the polarization of microglia from M1 to M2.","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 1","pages":"22-30"},"PeriodicalIF":1.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can minor trauma cause asymptomatic cervical spinal cord compression leading to severe cervical spinal cord injury in rats? 轻微外伤会导致大鼠无症状性颈椎脊髓压迫，从而导致严重的颈椎脊髓损伤吗？

IF 1.6 4区医学

Neuroreport Pub Date : 2025-01-08 Epub Date: 2024-11-06 DOI: 10.1097/WNR.0000000000002113

Luchun Xu, Ting Wang, Zheng Cao, Yushan Gao, Guozheng Jiang, Yukun Ma, Jiawei Song, Yongdong Yang, Xing Yu

{"title":"Can minor trauma cause asymptomatic cervical spinal cord compression leading to severe cervical spinal cord injury in rats?","authors":"Luchun Xu, Ting Wang, Zheng Cao, Yushan Gao, Guozheng Jiang, Yukun Ma, Jiawei Song, Yongdong Yang, Xing Yu","doi":"10.1097/WNR.0000000000002113","DOIUrl":"10.1097/WNR.0000000000002113","url":null,"abstract":"The study aimed to determine whether asymptomatic rats with cervical spinal cord compression (CSCC) experience more severe cervical spinal cord injury (SCI) compared with rats without CSCC under the same degree of minor trauma. Four weeks after the polyvinyl alcohol-polyacrylamide hydrogel was implanted into the C5 vertebral canal, asymptomatic rats were selected based on locomotor function score. Mild cervical SCI was subsequently established based on CSCC. The motor function, morphology, neuron loss, myelin destruction, nerve cell apoptosis, microglia activation, and neuroinflammation were evaluated after SCI. Under the same injury conditions, rats in the CSCC group exhibited more severe motor dysfunction compared with those without CSCC. Similarly, asymptomatic CSCC rats showed significant damage to spinal cord tissue, neurons, and myelin. Finally, compared with rats without CSCC, asymptomatic CSCC rats experienced increased nerve cell apoptosis, microglial activation, and neuroinflammation following the same SCI. In asymptomatic CSCC rats, the same degree of minor trauma resulted in more severe cervical SCI compared with rats without CSCC. This was evidenced by increased nerve cell apoptosis, microglial activation, neuron death, myelin destruction, and a strong neuroinflammatory response, leading to severe motor dysfunction.","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":" ","pages":"1-10"},"PeriodicalIF":1.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11661568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The influence of music elements on the understanding of emotional musical meaning: based on the perspective of interval structure. 音乐要素对情感音乐意义理解的影响：基于音程结构的视角。

IF 1.6 4区医学

Neuroreport Pub Date : 2025-01-08 Epub Date: 2024-12-04 DOI: 10.1097/WNR.0000000000002119

Tiantian Liu, Shuyi Liu, Zirui Ling, Songhan Liu, Lele Fang

{"title":"The influence of music elements on the understanding of emotional musical meaning: based on the perspective of interval structure.","authors":"Tiantian Liu, Shuyi Liu, Zirui Ling, Songhan Liu, Lele Fang","doi":"10.1097/WNR.0000000000002119","DOIUrl":"10.1097/WNR.0000000000002119","url":null,"abstract":"Music has become an indispensable part of people's lives, frequently encountered in various contexts of daily living. Understanding the emotional significance of music is a crucial foundation for its use. This study employed the cross-modal affective priming paradigm, combined with event-related potential technology to investigate the influence of music elements on the emotional musical meaning from the perspective of interval structure. Two different forms of musical intervals (melodic interval and harmonic interval) and intervals with different varying degrees of consonance were used as priming stimuli and emotional words as target stimuli. The research results found that, compared to melodic intervals, participants responded faster and with higher accuracy under the harmonic interval condition, which also elicited a larger N400 component. Furthermore, the N400 amplitudes were smaller in four conditions compared to the dissonant-positive and consonant-positive conditions, and the consonant-negative condition elicited a significantly larger N400 amplitude than the dissonant-negative and partially consonant-negative conditions. This finding suggest that both interval type and consonance level influence emotional musical meaning, and interval structure plays a critical role in the understanding of emotional musical meaning.","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":"36 1","pages":"47-54"},"PeriodicalIF":1.6,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of referential and emotional information on novel word learning: an fNIRS study. 参考信息和情绪信息对新单词学习的影响：一项fNIRS研究。

IF 1.6 4区医学

Neuroreport Pub Date : 2025-01-06 DOI: 10.1097/WNR.0000000000002135

Shan Li, Xue Sui, Yanbo Hu, Yutong Li

{"title":"The effect of referential and emotional information on novel word learning: an fNIRS study.","authors":"Shan Li, Xue Sui, Yanbo Hu, Yutong Li","doi":"10.1097/WNR.0000000000002135","DOIUrl":"10.1097/WNR.0000000000002135","url":null,"abstract":"The current study utilized functional near-infrared spectroscopy to examine the neural mechanisms underlying the effect of referential and emotional information on novel word learning. After learning the meaning of novel words in different sentences, participants were asked to complete a semantic consistency judgment task and a source judgment task. The behavioral data and neural data were recorded simultaneously. The results showed that: (1) referential information affected the novel word learning; (2) the interaction between referential and emotional information was significant; (3) these effects were associated with neural activities in the frontal and temporal lobe, mainly in the activation of the dorsolateral prefrontal cortex, the inferior frontal gyrus, the middle temporal gyrus, the superior temporal gyrus, and the premotor and supplementary motor cortex. The findings suggested that self-referential information could promote the novel word learning. Notably, referential and emotional information jointly affected the novel word learning in the frontal and temporal lobe, indicating the integrative contributions of both referential and emotional information to novel word learning.","PeriodicalId":19213,"journal":{"name":"Neuroreport","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0