NeuropsychologyPub Date : 2025-09-01Epub Date: 2025-05-26DOI: 10.1037/neu0001010
Daniel Soberanes, Mark A Dubbelman, Roos J Jutten, Cassidy P Molinare, Stephanie Hsieh, Hairin Kim, Geoffroy Gagliardi, Patrizia Vannini, Gad A Marshall, Kathryn V Papp, Rebecca E Amariglio
{"title":"Updating the self-appraisal of one's cognitive performance with 7 days of repeated exposure: From test-naïve to experienced.","authors":"Daniel Soberanes, Mark A Dubbelman, Roos J Jutten, Cassidy P Molinare, Stephanie Hsieh, Hairin Kim, Geoffroy Gagliardi, Patrizia Vannini, Gad A Marshall, Kathryn V Papp, Rebecca E Amariglio","doi":"10.1037/neu0001010","DOIUrl":"10.1037/neu0001010","url":null,"abstract":"<p><strong>Objective: </strong>Self-appraisal of cognitive performance, a potentially useful marker of brain functioning, is typically assessed at a single time point where tests are naïve to what constitutes \"good\" or \"bad\" performance. Here, we determine whether familiarizing individuals with self-appraisal with daily memory testing for 7 days provide a more accurate estimate of cognitive functioning and mood.</p><p><strong>Method: </strong>Two hundred twenty-five participants (<i>M</i><sub>age</sub> ± <i>SD</i>: 74.1 ± 8.3 years; 66% female; median education 16.0 years) completed the online Boston Remote Assessment for NeuroCognitive Health, which included two associative memory tasks, for seven consecutive days. Each day, participants self-appraised their performance. At baseline, they completed various cognitive and mood measures. We computed Pearson's correlations between task performance and self-appraisal on Days 1 and 7 and used linear models to examine the relationship between self-appraisal scores and clinical measures.</p><p><strong>Results: </strong>Accuracy (Day 1: 0.44 ± 0.12; Day 7: 0.81 ± 0.16) and self-appraisal (Day 1: 0.36 ± 0.15; Day 7: 0.70 ± 0.21) increased, as did the association between accuracy and self-appraisal, Day 1: correlation coefficient (<i>r</i>) = 0.22, 95% confidence interval (95% CI) [0.09, 0.34], <i>p</i> = .001; Day 7: <i>r</i> = 0.69, 95% CI [0.62, 0.76], <i>p</i> < .001. Self-appraisal scores on Day 7, but not Day 1, showed significant relationships with in-clinic measures.</p><p><strong>Conclusions: </strong>Repeated remote cognitive assessments may help elucidate individuals' capacities to refine their self-perception of cognitive performance during multiday learning. The weak association between accuracy and test-naïve self-appraisal warrants caution about using this metric cross-sectionally. Experienced self-appraisal could be especially relevant at the early stages of neurodegenerative diseases when subtle learning difficulties emerge and could improve our capacity to detect early meta-cognitive changes. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":"538-547"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144160609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuropsychologyPub Date : 2025-09-01Epub Date: 2025-04-07DOI: 10.1037/neu0001008
Kara L Stevens, Craig A Marquardt, Matthew A Tong, Nicholas D Davenport, Scott R Sponheim
{"title":"Posttraumatic stress symptomatology rather than mild traumatic brain injury is related to atypical early neural processing during cognitive control.","authors":"Kara L Stevens, Craig A Marquardt, Matthew A Tong, Nicholas D Davenport, Scott R Sponheim","doi":"10.1037/neu0001008","DOIUrl":"10.1037/neu0001008","url":null,"abstract":"<p><strong>Objective: </strong>Many veterans with posttraumatic stress disorder (PTSD) or a history of mild traumatic brain injury (mTBI) report disruptions in cognition; however, the neurophysiological underpinnings of these cognitive difficulties are not well understood. It is also unknown whether PTSD symptomatology or past mTBIs uniquely impact functions important to adaptation such as cognitive control.</p><p><strong>Method: </strong>We examined event-related potentials elicited by a flanker task to evaluate brain responses during conflict monitoring in a sample of 192 U.S. military veterans with combat-zone experience and exposure to explosive blasts. Clinical assessments characterized diagnoses as well as the severity of PTSD symptoms and mTBI so that we could parse overlapping syndromes and directly contrast effects of the two conditions.</p><p><strong>Results: </strong>Across groups, participants performed worse on conflict trials (Incongruent distractors), particularly when preceded by a no-conflict (Congruent distractors) trial. We found that greater dysphoric PTSD symptomatology was related to a reduced early perceptual response (P1), while greater avoidance PTSD symptomatology predicted a larger early visual attention response (N1). Although late cognitive processes (N2, P3) were sensitive to cognitive control demands of the flanker task, posttraumatic symptomatology and mTBI severity were unrelated to them.</p><p><strong>Conclusions: </strong>Results provide evidence that the Avoidance and Dysphoria domains of PTSD symptomatology may differentially relate to early neural functions of perception and visual attention rather than later cognitive responses. Rehabilitation and treatment of individuals with PTSD and mTBI may be most productive when focused on perceptual and attentional processing, which could improve cognitive control. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":"503-516"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nathan R Ramirez, Aaron J Zynda, Courtney Perry, Brooke Collins, Heather A Jasper, Jonathan E French, Michael W Collins, Alicia M Trbovich, Anthony P Kontos
{"title":"Comparison of multidomain assessment outcomes between older and middle-aged adults following concussion.","authors":"Nathan R Ramirez, Aaron J Zynda, Courtney Perry, Brooke Collins, Heather A Jasper, Jonathan E French, Michael W Collins, Alicia M Trbovich, Anthony P Kontos","doi":"10.1037/neu0001032","DOIUrl":"https://doi.org/10.1037/neu0001032","url":null,"abstract":"<p><strong>Objective: </strong>This article's objective was to compare demographic/medical history and multidomain clinical assessment outcomes between older and middle-aged adults following concussion.</p><p><strong>Method: </strong>Seventy-six patients aged 50-80 years within 12 months of a concussion from a specialty clinic between October 2021 and August 2023 participated in the study. Participants were grouped into older (≥60 years) and middle-aged (50-59 years) adults. At their first clinic visit, participants completed multidomain clinical assessments comprising symptoms, cognitive, vestibular/ocular motor, psychological health, and quality of life domains.</p><p><strong>Results: </strong>Older adults (<i>n</i> = 35) had less females (40.0% vs. 68.3%, <i>p</i> = .01), anxiety history (17.1% vs. 39.0%, <i>p</i> = .036), and employed individuals (57.1% vs. 82.9%, <i>p</i> = .002) than middle-aged adults (<i>n</i> = 41). Older adults had better Neuro-Quality of Life, <i>F</i>(1, 71) = 6.8, <i>p</i> = .01, η<sub>p</sub>² = 0.09; Repeatable Battery for the Assessment of Neuropsychological Status recall, <i>F</i>(1, 71) = 12.6, <i>p</i> < .001, η<sub>p</sub>² = 0.15; fluency, <i>F</i>(1, 71) = 5.7, <i>p</i> = .02, η<sub>p</sub>² = 0.08; list recall, <i>F</i>(1, 69) = 5.2, <i>p</i> = .03, η<sub>p</sub>² = 0.07; and list recognition, <i>F</i>(1, 69) = 5.3, <i>p</i> = .03, η<sub>p</sub>² = 0.07, when controlling for sex, anxiety history, and employment status. Older adults also had lower odds of being impaired to borderline on Immediate Post-Concussion Assessment and Cognitive Testing verbal memory (<i>OR</i> = 0.05, 95% CI [0.01, 0.56], <i>p</i> = .01), visual motor speed (<i>OR</i> = 0.08, 95% CI [0.01, 0.73], <i>p</i> = .03), and reaction time (<i>OR</i> = 0.21, 95% CI [0.05, 0.89], <i>p</i> = .03), and lower odds of having moderate to severe impairment on Neuro-Quality of Life (<i>OR</i> = 0.32, 95% CI [0.11, 0.97], <i>p</i> = .04) than middle-aged adults.</p><p><strong>Conclusions: </strong>Older adults (≥60 years) exhibited fewer subjective cognitive difficulties and objective cognitive impairments compared to middle-aged adults (50-59 years) following concussion. There were no differences between groups in symptoms, vestibular/ocular motor functioning, or psychological health. Clinicians should consider these findings when evaluating and interpreting outcomes from older and middle-aged adults following concussion. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashlyn Runk, Kayla Conaty, Matthew Calamia, Meryl A Butters, Ariel Gildengers
{"title":"Exploring the link between National Institutes of Health (NIH) Toolbox Cognition Battery performance and everyday functioning in mild cognitive impairment.","authors":"Ashlyn Runk, Kayla Conaty, Matthew Calamia, Meryl A Butters, Ariel Gildengers","doi":"10.1037/neu0001034","DOIUrl":"https://doi.org/10.1037/neu0001034","url":null,"abstract":"<p><strong>Objective: </strong>Neuropsychologists routinely use scores on traditional paper-and-pencil tests to assess capacity for independent functioning, with these assessments accounting for a moderate amount (20%-37%) of the variance in instrumental activities of daily living (IADL) performance. The field is shifting toward incorporation of computerized neuropsychological assessments such as the National Institutes of Health Toolbox Cognition Battery (NIHTB-CB). There have been no studies examining how the NIHTB-CB relates to IADL performance or whether it better predicts IADL performance compared to traditional methods.</p><p><strong>Method: </strong>Data from 74 participants in the Lithium as a Treatment to Prevent Impairment of Cognition in Elders were analyzed. Participants completed a neuropsychological assessment battery, the NIHTB-CB, and measures of IADL capacity. Linear regression was used to determine whether NIHTB-CB performance predicted IADL performance. Hierarchical multiple regression was used to determine whether NIHTB-CB added incremental validity to the prediction of IADL performance.</p><p><strong>Results: </strong>Select NIHTB-CB measures predicted IADL functioning as measured by a performance-based assessment of everyday functioning, but not self- or informant-reported everyday functioning. Of these subtests, two were found to add incremental validity to the prediction of IADL performance above and beyond their matched traditional measures, with effect sizes ranging from mild to moderate (<i>F</i>Δ<i>R</i>² = .045-.077).</p><p><strong>Conclusions: </strong>We found performance on individual NIHTB-CB subtests predicted approximately the same amount of variance in IADL functioning as traditional tests, with only subtests assessing processing speed and executive functioning adding a mild to moderate amount of additional variance above matched measures. It remains important for clinicians to consider additional determinants of functioning when using computerized assessments. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12380170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144962929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wilmar Pineda-Alhucema, Heidy Borja-Vargas, Beatriz Milagros Mendoza-Rincón, Juan Carlos Caicedo-Mera, Johana Escudero-Cabarcas
{"title":"The Reading the Mind in the Eyes Test for adults: A refined version in Spanish.","authors":"Wilmar Pineda-Alhucema, Heidy Borja-Vargas, Beatriz Milagros Mendoza-Rincón, Juan Carlos Caicedo-Mera, Johana Escudero-Cabarcas","doi":"10.1037/neu0001033","DOIUrl":"10.1037/neu0001033","url":null,"abstract":"<p><strong>Objective: </strong>The Reading of the Mind in the Eyes Test (RMET) is widely used to assess theory of mind, but its validity has recently been questioned. This study aimed to present a refined Spanish version of the test and examine its psychometric properties.</p><p><strong>Method: </strong>A total of 1,185 participants from Colombia completed the Spanish RMET. Exploratory and confirmatory factor analyses were conducted to examine its internal structure. Item response theory was applied to evaluate item quality. A test-retest analysis was performed, and standardization norms were developed for urban Colombian adults.</p><p><strong>Results: </strong>A refined 24-item version (RMET-24) is proposed, retaining items from the original 36-item test. Twelve items were excluded due to poor discrimination and evidence of guessing, as indicated by item response theory. The RMET-24 showed a unifactorial structure with suitable difficulty and discrimination indices, adequate test-retest stability, and satisfactory reliability. Scoring norms for the Colombian sample were established using linear regression.</p><p><strong>Conclusions: </strong>The RMET-24 offers improved psychometric properties over the original version. Its refined indices make it appropriate for clinical populations. While suitable for neuropsychological assessments, future updates should consider incorporating color stimuli. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daliah Ross, Mark E Wagshul, Frederick W Foley, Roee Holtzer
{"title":"Moderating effects of limbic white matter on verbal memory in older adults with multiple sclerosis.","authors":"Daliah Ross, Mark E Wagshul, Frederick W Foley, Roee Holtzer","doi":"10.1037/neu0001023","DOIUrl":"10.1037/neu0001023","url":null,"abstract":"<p><strong>Objective: </strong>Literature concerning the structural brain correlates of verbal memory in aging with multiple sclerosis (MS) is scarce. This study addressed this gap by examining the impact of white matter microstructure and macrostructure on verbal memory in older adults with and without MS.</p><p><strong>Method: </strong>Participants were 64 older adults with MS (OAMS; age <i>M</i> [<i>SD</i>] = 64.19 [3.82]) and 72 controls (age <i>M</i> [<i>SD</i>] = 69.78 [6.99]). Verbal memory was measured using the Hopkins Verbal Learning Test-Revised (HVLT-R), and white matter fractional anisotropy and lesion volume were extracted from diffusion tensor and fluid-attenuated inversion-recovery magnetic resonance imaging. Statistical models examined whether white matter measures moderated the association between the presence of MS and HVLT-R performance.</p><p><strong>Results: </strong>Adjusted moderation models revealed that OAMS showed lower HVLT-R total immediate recall compared to controls in the presence of higher lesion volume in the bilateral fornices, left uncinate fasciculus, and right ventral cingulum, and lower HVLT-R delayed recall in the presence of lower fractional anisotropy in the right ventral cingulum and higher lesion volume in the left uncinate fasciculus and right ventral cingulum, with small effect sizes (interaction term Δ<i>R</i>²s = .03-.06, <i>p</i>s < .05).</p><p><strong>Conclusions: </strong>Recall was lower in OAMS when limbic tract white matter had lower integrity and higher lesion load. Findings suggest that the influence of MS on verbal memory in older adults is related, in part, to underlying white matter disruptions in tracts implicated in memory. While the sample was generally representative of the U.S. MS population (majority White women), generalizability is limited and warrants further research. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12313107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The classification accuracy of the recognition memory test-words as a performance validity test is affected by gender and education.","authors":"Laszlo A Erdodi","doi":"10.1037/neu0001027","DOIUrl":"10.1037/neu0001027","url":null,"abstract":"<p><strong>Objective: </strong>Previous research suggested that Recognition Memory Test-Words (RMT-W) scores may be confounded by gender and handedness. This study was designed to examine its classification accuracy as a performance validity test (PVT) and susceptibility to demographic characteristics.</p><p><strong>Method: </strong>Archival data were collected from a consecutive sequence of 310 diagnostically heterogeneous examinees (181 men; <i>M</i><sub>Age</sub> = 41.4; <i>M</i><sub>Education</sub> = 12.9). The RMT-W's classification accuracy was computed against psychometrically operationalized criterion groups.</p><p><strong>Results: </strong>Optimal RMT-W cutoffs (≤ 42 to ≤ 40) produced a good combination of sensitivity (.62-.70) and specificity (.90-.96), correctly classifying 85.6%-87.7% of the sample. Women scored 1.5 points higher. RMT-W scores were unrelated to handedness but were correlated with education. A linear relationship emerged between level of education and the cutoff needed to achieve ≥ .90 specificity: ≤ 43 for ≥ 13 years of education, ≤ 41 for 12 years of education, and ≤ 39 for ≤ 11 years of education. RMT-W ≤ 45 had .91 specificity in women with postsecondary education.</p><p><strong>Conclusions: </strong>Results suggest that overall, the RMT-W remains an effective free-standing PVT. Gender, age, and handedness in isolation had minimal impact on RMT-W scores. However, education had a clinically significant effect. The combined effect of gender and education produced a marked shift in classification accuracy. Systematic research is needed on the relationship between demographics and PVT outcomes to ensure that cutoffs have the same clinical interpretation regardless of patient variables. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefanie Gard, Joseph Saad, Christine L Sheppard, Vanessa Taler
{"title":"Monolinguals outperform bilinguals in language but not executive function in aging and cognitive impairment.","authors":"Stefanie Gard, Joseph Saad, Christine L Sheppard, Vanessa Taler","doi":"10.1037/neu0001028","DOIUrl":"10.1037/neu0001028","url":null,"abstract":"<p><strong>Objective: </strong>People with subjective cognitive decline (SCD) self-report declining cognitive function, although objective cognitive performance remains normal. SCD is a risk factor for mild cognitive impairment (MCI) and dementia. Previous research has found differences in cognitive performance in bilinguals compared with monolinguals. We examined cognitive performance in older adults with and without SCD, and the association between bilingualism and cognitive performance in cognitively healthy older adults, people with SCD, and people with MCI, and the influence of bilingualism on the age of MCI diagnosis.</p><p><strong>Method: </strong>Adults aged 65+ (<i>n</i> = 264) rated their ability in French and English and self-perceived change in concentration and attention, memory, and word-finding. They then completed neuropsychological tests assessing language, memory, and executive function. Participants were monolingual or bilingual and were older adults, reported amnestic or nonamnestic SCD, or had MCI.</p><p><strong>Results: </strong>No differences in cognitive performance were observed between older adults and people with SCD, while people with MCI had lower performance on nearly all tasks. Monolinguals outperformed bilinguals in the Boston Naming Test, letter-number sequencing, California Verbal Learning Test, FAS, animal, vegetable/musical instrument, and A/F switch fluency tasks, but group performance did not differ on executive function tasks. Sensitivity analyses using English L1 bilinguals who completed the first administration of the language tasks in the English or bilingual version showed that monolinguals outperformed bilinguals on only the Boston Naming Test. Monolinguals had a later age of MCI diagnosis than bilinguals in our sample.</p><p><strong>Conclusions: </strong>These findings suggest that the protective effect of bilingualism reported elsewhere in the literature is not universal. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuropsychologyPub Date : 2025-07-01Epub Date: 2025-05-12DOI: 10.1037/neu0001017
Hong He, Yunyun Chen, Xuemin Zhang
{"title":"Resting-state intrinsic network connectivity and mind wandering: Insights from tasks with varying demands.","authors":"Hong He, Yunyun Chen, Xuemin Zhang","doi":"10.1037/neu0001017","DOIUrl":"10.1037/neu0001017","url":null,"abstract":"<p><strong>Objective: </strong>Recent research has uncovered that mind wandering, as evaluated through a mind wandering questionnaire, is linked to heightened functional connectivity within the default mode network (DMN) and increased functional connectivity between the DMN and the frontoparietal control network (FPCN). However, limited research has focused on the association between mind wandering and resting-state network functional connectivity in relation to task demands.</p><p><strong>Method: </strong>This study aimed to address this issue by collecting data on resting-state functional magnetic resonance imaging images and mind wandering during 0-back and 1-back tasks outside the scanner (<i>N</i> = 93). The study examined how resting-state functional connectivity within and between intrinsic brain networks (DMN, FPCN, and dorsal attention network) is associated with mind wandering during tasks of different cognitive loads.</p><p><strong>Results: </strong>The results of the study revealed a significant positive correlation between mind wandering and resting-state within-network connectivity of the DMN in both tasks. Additionally, in the 0-back task, mind wandering exhibited a significant positive correlation with resting-state connectivity between the DMN and the FPCN. In the 1-back task, mind wandering demonstrated a significant positive correlation with resting-state connectivity between the DMN and the dorsal attention network.</p><p><strong>Conclusions: </strong>These findings are consistent with previous findings and further suggest that the relationship between resting-state network functional connectivity and mind wandering is sensitive to task demands. They lend support to the context regulation hypothesis, suggesting that executive function may regulate mind wandering frequency based on situational demands. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":"450-462"},"PeriodicalIF":3.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NeuropsychologyPub Date : 2025-07-01Epub Date: 2025-04-07DOI: 10.1037/neu0001005
Rhian S Convery, Kerala Adams-Carr, Jennifer M Nicholas, Katrina M Moore, Sophie Goldsmith, Martina Bocchetta, Lucy L Russell, Jonathan D Rohrer
{"title":"Concurrent validity, test-retest reliability, and normative properties of the ignite app: A cognitive assessment for frontotemporal dementia.","authors":"Rhian S Convery, Kerala Adams-Carr, Jennifer M Nicholas, Katrina M Moore, Sophie Goldsmith, Martina Bocchetta, Lucy L Russell, Jonathan D Rohrer","doi":"10.1037/neu0001005","DOIUrl":"10.1037/neu0001005","url":null,"abstract":"<p><strong>Objective: </strong>Digital biomarkers can provide frequent, real-time monitoring of health-related behavior and could play an important role in the assessment of cognition in frontotemporal dementia (FTD). However, the validity and reliability of digital biomarkers as measures of cognitive function must first be determined.</p><p><strong>Method: </strong>The Ignite cognitive app contains iPad-based measures of executive function, social cognition, and other domains affected in FTD. Here we describe the normative properties of the Ignite tests, evaluate associations with gold-standard neuropsychological tests, and investigate test-retest reliability through two healthy control studies. Over 2,000 cognitively normal adults aged 20-80 years were recruited to complete the Ignite app remotely. A separate cohort of 98 healthy controls completed Ignite at two timepoints (7 days apart), a pen and paper neuropsychology battery, and a User Experience Questionnaire.</p><p><strong>Results: </strong>Significant associations were found between age and performance on several Ignite measures of processing speed (<i>r</i> = 0.42-0.56, <i>p</i> < .001) and executive function (<i>r</i> = 0.43-0.62, <i>p</i> < .001). With the exception of one test (Time Tap), the Ignite tests demonstrated moderate to excellent test-retest reliability (intraclass correlation coefficients [ICC] = 0.54-0.92) and significant correlations with their pen and paper counterparts (<i>r</i> = 0.25-0.72, <i>p</i> < .05). The majority of participants (> 90%) rated the app favorably, stating it was enjoyable and easy to complete unsupervised.</p><p><strong>Conclusions: </strong>These findings offer early support for the validity of the Ignite tests suggesting they measure the intended cognitive processes, capture a stable picture of performance over time, and are well accepted in healthy controls. This work supports the feasibility of administering the app remotely and its potential utility as a cognitive tool in FTD; however, validation is ongoing, and further work is required before Ignite can be used as an endpoint in clinical trials. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":"402-421"},"PeriodicalIF":2.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}