Neuropsychology最新文献

{"title":"Phonological networks remain intact in multiple sclerosis.","authors":"Allison Link, Amy L Lebkuecher, Abigail L Cosgrove, Nichol Castro, Nancy D Chiaravalloti, Lauren B Strober, Michele T Diaz","doi":"10.1037/neu0001040","DOIUrl":"10.1037/neu0001040","url":null,"abstract":"<p><strong>Objective: </strong>Multiple sclerosis (MS) is a neurological condition characterized by white and gray matter decline that leads to slower motor function and cognitive impairment. Although language remains relatively intact, individuals with MS often have word retrieval difficulties. Previous research suggests that these difficulties may be related to vocabulary, the number of words an individual knows, and other semantic aspects of language. However, few studies have examined phonological aspects of speech.</p><p><strong>Method: </strong>We examined speech in 89 individuals with MS and 88 age-matched neurotypical adults using a phonemic verbal fluency task. We took a network science approach, building a phonological network from participants' responses and their close phonological neighbors. We then examined the local network characteristics (degree, clustering coefficient) of participants' responses to assess whether responses differed between the groups.</p><p><strong>Results: </strong>Although individuals with MS produced fewer responses during the task, the network characteristics of their responses were similar to neurotypical adults, the control group. Moreover, lexical characteristics such as word length and lexical frequency were also similar between groups (model <i>R</i>² values < 1%). Finally, a forward flow analysis, which quantifies the phonological similarity between adjacent responses and provides a metric of how people search phonemic space, did not differ between groups.</p><p><strong>Conclusions: </strong>Overall, these results suggest that phonological aspects of speech remain stable in individuals with MS. Word retrieval difficulties in MS may arise from neurological changes in semantic processes, in combination with other cognitive abilities such as speed of processing and executive function, which are common in MS. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12462895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moral decision making and moral judgment in multiple sclerosis.","authors":"Federica Satriano, Antonella Di Vita, Giorgio Leodori, Daniele Belvisi, Leonardo Malimpensa, Angelo Collura, Simona Raimo, Antonella Conte, Gina Ferrazzano","doi":"10.1037/neu0001030","DOIUrl":"https://doi.org/10.1037/neu0001030","url":null,"abstract":"<p><strong>Objective: </strong>Moral cognition has been insufficiently studied in people with multiple sclerosis (pwMS). This study investigated moral decision making and judgment using ecologically valid moral dilemmas in relapsing-remitting multiple sclerosis (MS) and progressive MS phenotypes, exploring associations with clinical and psychological variables.</p><p><strong>Method: </strong>Twenty-one individuals with relapsing-remitting MS and 21 with progressive MS completed a battery of moral dilemmas (instrumental, incidental, and ecological) and questionnaires assessing quality of life, mood, alexithymia, and empathy. Data from pwMS were compared to those of 56 age- and education-matched healthy controls. Group differences were analyzed using Mann-Whitney U tests, and effect sizes (<i>r</i>) were reported.</p><p><strong>Results: </strong>Compared to healthy controls, pwMS showed significantly higher moral acceptability in instrumental (<i>U</i> = 633.0, <i>p</i> = .001, <i>r</i> = 0.39), incidental (<i>U</i> = 745.5, <i>p</i> = .035, <i>r</i> = 0.23), and ecological dilemmas (<i>U</i> = 563.0, <i>p</i> < .001, <i>r</i> = 0.44). Moral permissiveness was positively correlated with disability (Expanded Disability Status Scale: ρ = 0.36, <i>p</i> = .019) and negatively with physical quality of life (Multiple Sclerosis Quality of Life-Physical: ρ = -0.33, <i>p</i> = .034) and inhibitory control (Stroop Test: ρ = 0.47, <i>p</i> = .002). Empathy scores were inversely correlated with moral acceptability across all dilemmas (<i>p</i> < .05).</p><p><strong>Conclusions: </strong>PwMS exhibit increased moral permissiveness, particularly in relation to clinical disability, physical functioning, and executive control. These findings contribute to characterizing the sociocognitive profile of MS and support the inclusion of moral cognition in future research, though implications for patient care remain preliminary. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of immersive virtual reality line and baguette bisection tasks for the assessment of unilateral spatial neglect.","authors":"Marine Gaffard, Clémence Bourlon, Tristan-Gaël Bara, Tifanie Bouchara, Florence Colle, Silvia Silvestri, Perrine Quentin, Alma Guilbert","doi":"10.1037/neu0001024","DOIUrl":"https://doi.org/10.1037/neu0001024","url":null,"abstract":"<p><strong>Objective: </strong>Unilateral spatial neglect (USN) assessment is commonly based on paper-and-pencil tests, including the line bisection task. However, this task lacks sensitivity and does not reflect the symptomatic heterogeneity of USN patients, such as difficulties in extrapersonal space or encountered in daily life. Immersive virtual reality (VR) could be a promising way to improve the line bisection task by developing versions that better reflect the difficulties experienced by patients. This study investigated the feasibility and the psychometric qualities of different immersive VR bisection tasks.</p><p><strong>Method: </strong>22 right-brain damaged patients with confirmed left USN (USN++) on conventional USN assessment tools, signs of left USN (USN+), or without USN (USN-), and 39 healthy participants were recruited and performed three different immersive VR bisection tasks-a proximal and a distal line bisection task and an ecological baguette bisection task.</p><p><strong>Results: </strong>Correlational analyses with conventional USN assessment tools supported the validity of the immersive VR bisection tasks. Group and individual analyses emphasized the better sensitivity of the immersive VR proximal and ecological tasks compared with the paper-and-pencil line bisection task. The immersive VR proximal bisection task showed high sensitivity to detecting USN++ patients (detection rate: 75.0%) but not USN+ patients, while the immersive VR ecological bisection task showed good sensitivity for detecting both (detection rate: 62.5%), supporting its relevance for diagnosing mild USN.</p><p><strong>Conclusions: </strong>The immersive VR bisection tasks appear relevant for USN diagnosis, especially the ecological one, which supports the need for more ecological assessment tools to assess USN and plan rehabilitation better. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Updating the Mattis Dementia Rating Scale to DSM-5-TR/ICD-11: A new item-division based on the current neurocognitive domains.","authors":"Jonas J de Paula, Lafaiete G Moreira, Rafaela T Ávila, Rodrigo Nicolato, Marco A Romano-Silva, Bernardo M Viana, Maria Aparecida C Bicalho","doi":"10.1037/neu0001029","DOIUrl":"https://doi.org/10.1037/neu0001029","url":null,"abstract":"<p><strong>Objective: </strong>The Mattis Dementia Rating Scale (DRS), a widely used cognitive assessment tool, has been revised to align with contemporary diagnostic criteria and cognitive domain classifications such as those outlined in <i>Diagnostic Statistical Manual for Mental Disorders</i>, fifth edition-text revision (DSM-5-TR) and <i>eleventh version of the International Classification of Diseases (ICD-11).</i> This study proposed a reorganization of DRS items into five new subscales based on cognitive domains of those classificatory manuals, aiming to enhance its construct validity and clinical utility.</p><p><strong>Method: </strong>The DRS and other neuropsychological tests were used for the assessment of 407 older adults with low formal education and heterogeneous cognitive backgrounds. We used confirmatory factor analysis to test different arrangements of DRS items and correlated the final model with other neuropsychological tests.</p><p><strong>Results: </strong>Our final model (following the <i>DSM-5-TR/ICD-11</i> cognitive domains) showed better model fit in multiple indexes when compared with the original DRS subscales. They showed significant correlation with specific neuropsychological tests corresponding to their respective cognitive domains, supporting its validity. Group comparisons across cognitive impairment levels (cognitively unimpaired, mild neurocognitive disorder, major neurocognitive disorder) revealed progressive cognitive decline patterns consistent with clinical expectations.</p><p><strong>Conclusions: </strong>The proposed DRS item division based in <i>DSM-5-TR</i> and <i>ICD-11</i> cognitive domains showed more consistent evidences of validity than the original. The proposed revision can use the original DRS subtests and scoring system, just reorganizing the subscales to better fit the <i>DSM-5-TR/ICD-11</i> model and can in any translation/local version of the test. Further research is needed to replicate this findings and establish normative values and cutoff scores for clinical application. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neural correlates of stigma: A systematic review.","authors":"Nele Loecher, Jennifer T Tran, Kristin Kosyluk, Inge Timmers","doi":"10.1037/neu0001037","DOIUrl":"https://doi.org/10.1037/neu0001037","url":null,"abstract":"<p><strong>Objective: </strong>Understanding neural mechanisms underlying the experience and enactment of stigma is needed to address the public health challenge posed by both experienced and enacted stigma. In this systematic review, we synthesized the literature on neural correlates of stigma from the perspective of (a) the stigmatizer (enacted stigma) and (b) the stigmatized (experienced stigma).</p><p><strong>Method: </strong>We searched PsychInfo, PubMed, Web of Science, Medline, and SCOPUS for articles assessing stigma using neuroimaging.</p><p><strong>Results: </strong>Thirty-one articles were included covering a variety of stigmatized identities (i.e., mental health, medical conditions, homelessness), with 20 articles on enacted stigma and 11 on experienced stigma. There was a large variety in methodological approaches, including varying experimental paradigms, analytical approaches (e.g., whole-brain vs. region-of-interest analyses), samples, and degree to which stigma is assessed and/or verified (as opposed to assumed to be present in response to exclusion or in response to specific stimuli). Regardless, our review indicates that a widespread network of brain regions is implicated in the enactment of stigma (in the stigmatizer), including frontal, cingulate, parietal, occipital, and subcortical regions, which are characterized by inconsistencies that likely result from methodological differences. In contrast, a blunted medial prefrontal cortex response to experienced stigma is relatively consistently observed (in the stigmatized).</p><p><strong>Conclusions: </strong>Our review is the first to comprehensively synthesize studies examining neural correlates of stigma, revealing tangible brain patterns reflecting its experience and enactment, enhancing our understanding of stigma and its assessment. Last, we highlight the complexity of this research area and discuss insights and considerations for future work. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Field usability and validity of eye-tracking instrumentation with the Early Childhood Vigilance Test among children aged 2-4 years old in Northern Coastal Ecuador.","authors":"Itziar Familiar-Lopez, Hannah Lalonde, Andrew Harris, Elizabeth Foot, María Sol Garcés, Nergiz Turgut, Karen Levy, Joseph N S Eisenberg, Gwenyth O Lee","doi":"10.1037/neu0001012","DOIUrl":"10.1037/neu0001012","url":null,"abstract":"<p><strong>Objective: </strong>There is a need for effective cognitive assessment tools to evaluate the development of very young children in resource-limited low- and middle-income country settings. Our objective was to evaluate the field usability of a computer-based attention test and its concurrent validity with a caregiver-reported screener of neurodevelopment in rural, Ecuadorian children.</p><p><strong>Method: </strong>To assess a computer-based attention test in a resource-limited setting, 41 Ecuadorian children between 2 and 4 years of age were evaluated once with the Early Childhood Vigilance Test (ECVT) of attention adapted to eye-tracking instrumentation. To evaluate the validity of the ECVT, results were compared with the Ages and Stages Questionnaire-3, measured 3-4 times between 21 and 48 months of age.</p><p><strong>Results: </strong>ECVT measures were collected successfully for 97.6% of children (40/41), suggesting good field usability of the test in this resource-limited setting. An increase in 1 SD in child attention, as measured by the ECVT average fixation duration, was associated with a 7.9-point increase in the overall Ages and Stages Questionnaire-3 score (95% CI [1.5, 14.2], <i>p</i> = .015).</p><p><strong>Conclusions: </strong>A computer-based attention assessment in early childhood was usable in a resource-limited setting and predictive of a caregiver-reported screener of child neurodevelopment. The ECVT, therefore, can be used to assess the effects of early risk factors and resilience in brain/behavior development. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":"561-569"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elongated tau in an ex-Gaussian decomposition of vocal articulation speed in children with attention deficit hyperactivity disorder.","authors":"Xu Yan, Hilary Galloway-Long, Alexander Weigard, Katherine All, Alexandra Roule, Tyler Warner, Christina Hlutkowsky, Cynthia Huang-Pollock","doi":"10.1037/neu0001015","DOIUrl":"10.1037/neu0001015","url":null,"abstract":"<p><strong>Objective: </strong>Slower and more variable reaction time is one of the most prominent cognitive signatures in childhood attention-deficit/hyperactivity disorder (ADHD). However, standard use of tasks that involve motor responses to index \"speed\" potentially confounds fine-motor coordination with central cognitive processing speed. One promising alternative is a vocal articulation task, which provides a measure of speeded performance that is independent of fine-motor coordination.</p><p><strong>Method: </strong>The present study applies an ex-Gaussian decomposition to preparatory interval (the time to initiate a vocal response) and speech rate on a speeded articulation task among children aged 8-12 with and without ADHD (<i>N</i> = 119).</p><p><strong>Results: </strong>There was substantial evidence that the tail of the distribution, as indexed by the <i>tau</i> parameter (which is linked to the rate of information accumulation), was larger in children with ADHD and among children with low working memory capacity (regardless of ADHD status). Variance in <i>tau</i> was also greater among children with ADHD, and the greater variance was not fully explained by individual differences in working memory.</p><p><strong>Conclusions: </strong>Results highlight the importance of adopting analytic methods that can more accurately describe performance. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":"548-560"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Joint effects of human immunodeficiency virus (HIV) and cannabis on neurocognition.","authors":"Ashley R Adams, Sarah M Lehman, Erin L Thompson, Christine M Kaiver, Diego Lopez, Samuel W Hawes, Brenda Lerner, Catalina Lopez-Quintero, Raul Gonzalez","doi":"10.1037/neu0001003","DOIUrl":"10.1037/neu0001003","url":null,"abstract":"<p><strong>Objective: </strong>Cannabis has become increasingly accessible to populations living with chronic health conditions such as HIV. Many people living with HIV are turning to cannabis for symptom relief despite the unclear risks to neurocognitive health. Our study sought to replicate and extend prior research by examining global and domain-specific neurocognitive performance between four groups stratified by use of cannabis (CB; CB+/CB-) and HIV serostatus (HIV+/HIV-).</p><p><strong>Method: </strong>Our demographically diverse community sample (<i>N</i> = 269) underwent exclusion and inclusion criteria to isolate the effects of cannabis use (CU) and HIV on neurocognition. We explored between-group comparisons of neurocognitive performance, probability of neurocognitive impairment, and interactive effects of CU/HIV serostatus.</p><p><strong>Results: </strong>Between-group comparisons revealed nonsignificant differences in global or domain-specific neurocognitive performance. However, the CB+/HIV+ group was three times (99% CI [1.18, 9.57]) more likely to be labeled with a memory impairment compared to the control (CB-/HIV-), and the CB+/HIV- group was twice (99% CI [.14, 7.47]) as likely to be labeled with an executive functioning impairment compared to the control. We also identified an interactive effect between the past 30-day CU and HIV serostatus for global (<i>b</i> = -.026, 99% CI [-.04, -.01]) and motor (<i>b</i> = -.052, 99% CI [-.07, -.03]) neurocognitive performance. Findings support a nuanced relationship between CU and HIV, which may partly explain mixed literature.</p><p><strong>Conclusions: </strong>Although we conclude that recent and heavy CU poses risk of neurocognitive decline among people living with HIVs, this effect is modest. Physicians and patients must weigh a possible decrease in global and motor neurocognition against the severity of symptoms being treated. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":"473-489"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144675361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robust longitudinal neuropsychological norms in Spanish individuals with nonpathological Alzheimer's disease biomarkers.","authors":"David López-Martos, Anna Brugulat-Serrat, Marc Suárez-Calvet, Marta Milà-Alomà, Carolina Minguillon, Juan Domingo Gispert, Henrik Zetterberg, Kaj Blennow, Oriol Grau-Rivera, Gonzalo Sánchez-Benavides","doi":"10.1037/neu0001013","DOIUrl":"10.1037/neu0001013","url":null,"abstract":"<p><strong>Objective: </strong>Neuropsychological norms serve to identify cognitive impairment and monitor neurodegenerative disease progression. However, longitudinal data are limited, and conventional approaches do not account for biomarkers to exclude underlying Alzheimer's disease (AD) pathology, reducing sensitivity to detect subtle cognitive decline in preclinical AD. To address these limitations, this research provides robust longitudinal neuropsychological norms derived from Spanish individuals with nonpathological levels of AD biomarkers.</p><p><strong>Method: </strong>We analyzed 3-year follow-up data from 350 cognitively unimpaired individuals (Alzheimer's and Families+ cohort). A subset of 228 individuals with normal cerebrospinal fluid amyloid-β42/40, phosphorylated-tau181, and total-tau biomarkers defined the robust reference group. Neuropsychological assessment encompassed the Trail Making Test, Free and Cued Selective Reminding Test, Memory Binding Test, Wechsler Adult Intelligence Scale-IV, Wechsler Memory Scale-IV, Semantic Fluency Test, and Judgment of Line Orientation from the Repeatable Battery for the Assessment of Neuropsychological Status. Using the Reliable Change Index and Standardized Regression-Based methods, robust longitudinal neuropsychological norms were derived from the reference group. Validation analysis assessed the sensitivity of robust versus conventional normative procedures.</p><p><strong>Results: </strong>Models, equations, percentiles, and cutoffs for identifying significant cognitive decline were provided. Robust norms showed modestly greater sensitivity in certain measures, particularly in episodic memory. The Free and Cued Selective Reminding Test: Total Free Delayed Recall showed the most notable result at the 5th percentile in Reliable Change Index (χ² = 16.06, <i>p</i> = 6.15E-05).</p><p><strong>Conclusions: </strong>Robust longitudinal neuropsychological norms may improve the detection of subtle cognitive decline, modestly enhancing sensitivity at the lower ends of distributions. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":"517-537"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acquired crowding dyslexia: A peripheral reading deficit other than neglect dyslexia.","authors":"Roberta Daini, Laura Veronelli, Alessio Facchin, Felicia Pasquale, Matteo Sozzi, Massimo Corbo, Lisa S Arduino","doi":"10.1037/neu0001014","DOIUrl":"10.1037/neu0001014","url":null,"abstract":"<p><strong>Objectives: </strong>Crowding refers to the phenomenon whereby small visual objects above the acuity threshold are detected but unrecognizable when surrounded by nearby stimuli. It affects reading in healthy individuals and can be enhanced in reading impairments. By increasing the interletter space, crowding decreases. Previous evidence on patients with unilateral spatial neglect (USN) and peripheral dyslexia has shown a dissociation in sensitivity to spacing manipulation between those who mainly produced omissions and those characterized by substitutions in reading. Here, we wanted to verify the hypothesis that the reading impairment mainly characterized by substitutions is dissociated from USN, unlike the one characterized by omissions.</p><p><strong>Method: </strong>In a retrospective study, we collected 38 right-brain-damaged patients, 21 with USN. We analyzed the number and types of errors in reading single words and pseudowords, spaced and unspaced, comparing patients with and without USN.</p><p><strong>Results: </strong>USN patients showed significantly more omissions than patients without USN and increased omissions with letter spacing. Substitutions were more frequent in USN patients but did not increase with spacing. Performance of patients mainly characterized by substitutions revealed a reduction of errors with spaced pseudowords and a double dissociation from USN. Lesion overlap analysis suggested that the two deficits could depend on different components of visuospatial attention networks.</p><p><strong>Conclusions: </strong>We claim that proper neglect dyslexia is characterized by omission errors and has USN as a necessary mechanism, even if not sufficient. Conversely, acquired crowding dyslexia is a different reading deficit, characterized by substitutions due to an enhanced crowding phenomenon, independent of USN. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":"490-502"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}