Neuropsychology最新文献

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ChatGPT in intervention planning: Advancing clinical relevance and targeted care in cognitive rehabilitation. ChatGPT在干预计划中的应用:促进认知康复的临床相关性和针对性护理。
IF 3 3区 心理学
Neuropsychology Pub Date : 2026-04-27 DOI: 10.1037/neu0001088
Natalie F Edman, Megan L Lacritz, Keren Isufi, Andrew D Lokai, Heidi A Bender, Amanda Sacks-Zimmerman
{"title":"ChatGPT in intervention planning: Advancing clinical relevance and targeted care in cognitive rehabilitation.","authors":"Natalie F Edman, Megan L Lacritz, Keren Isufi, Andrew D Lokai, Heidi A Bender, Amanda Sacks-Zimmerman","doi":"10.1037/neu0001088","DOIUrl":"https://doi.org/10.1037/neu0001088","url":null,"abstract":"<p><strong>Objective: </strong>We aim to introduce ChatGPT as a supportive tool in cognitive rehabilitation, examine the feasibility of its integration into clinical practice, and propose guidelines for its integration into evidence-based practice. The article is intended to provide a preliminary framework for how ChatGPT can be incorporated into cognitive rehabilitation therapy and does not serve as an empirical study.</p><p><strong>Method: </strong>We examine how artificial intelligence can assist cognitive rehabilitation interventionalists in targeting interventions to enhance clinical relevance. We present an illustrative intervention protocol guided by current cognitive rehabilitation principles and offer case examples demonstrating ChatGPT's role in creating clinically relevant practice activities tailored to individual needs.</p><p><strong>Results: </strong>Anecdotal feedback from patients was positive, with the patients reporting that practicing cognitive strategies using personally relevant information was enjoyable and easier to engage with compared to general practice tasks. This suggests that AI-generated tasks were engaging and relevant.</p><p><strong>Conclusion: </strong>The two cases provide an initial demonstration of how ChatGPT could be used to support the generation of personally relevant practice stimuli in cognitive rehabilitation, though further research is needed to assess its effectiveness and broader applicability. Importantly, the interventionist's expertise and active role in treatment planning, strategy selection, and progress evaluation remain central to the therapeutic process. We suggest that AI be utilized only as a supplemental tool in cognitive rehabilitation therapy, preserving the interventionist's active role in the therapeutic process. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147777351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Everyday executive functions in children with neurofibromatosis type 1: Data from nine institutions. 1型神经纤维瘤病儿童的日常执行功能:来自9个机构的数据
IF 3 3区 心理学
Neuropsychology Pub Date : 2026-04-16 DOI: 10.1037/neu0001087
Xiaoli Zong, Dan Liu, Xian Wu, Pamela L Wolters, Jonathan M Payne, Bonita P Klein-Tasman, Karin S Walsh, Jennifer Janusz, Natalie Pride, Stephanie M Morris, Carrie E Bearden, Peter L Stavinoha, Yang Hou
{"title":"Everyday executive functions in children with neurofibromatosis type 1: Data from nine institutions.","authors":"Xiaoli Zong, Dan Liu, Xian Wu, Pamela L Wolters, Jonathan M Payne, Bonita P Klein-Tasman, Karin S Walsh, Jennifer Janusz, Natalie Pride, Stephanie M Morris, Carrie E Bearden, Peter L Stavinoha, Yang Hou","doi":"10.1037/neu0001087","DOIUrl":"10.1037/neu0001087","url":null,"abstract":"<p><strong>Objective: </strong>Executive function (EF) difficulties are prevalent in neurogenetic syndromes such as Neurofibromatosis Type 1 (NF1), the most common autosomal dominant condition associated with nervous system tumors. However, age-related differences in EF problems in children with NF1 remain poorly understood. This study aimed to examine how EF problems in daily life vary across ages throughout childhood and adolescence and how these age patterns vary across demographic and NF1 disease-related characteristics.</p><p><strong>Method: </strong>This study integrated data of 1,294 observations from 1,025 children with NF1 (<i>M</i><sub>age</sub> = 9.77 years, <i>SD</i> = 4.06, range = 3-18) from nine institutions in the United States and Australia. EF was reported by parents using the Behavior Rating Inventory of Executive Function. Time-varying effect modeling was used to estimate curvilinear EF trends.</p><p><strong>Results: </strong>Children with NF1 demonstrated elevated EF problems compared to the normative mean from early childhood through late adolescence, with deviations generally largest from midchildhood through midadolescence. At ages showing the greatest deviations from the normative mean, medium to large EF gaps were observed across five core domains (Cohen's <i>d</i> = 0.73-1.42). The exact age patterns varied across EF domains and by children's sex, parental education, and NF1 inheritance.</p><p><strong>Conclusions: </strong>Leveraging the largest EF data set of children with NF1 to date, this study precisely estimated EF problems across developmental periods and highlighted the heterogeneity in EF age patterns. These age-specific estimates are crucial for establishing EF developmental norms that guide clinical practice and patient management strategies. The findings can inform the design of individualized intervention and prevention strategies tailored to various developmental periods and diverse demographic and disease-related characteristics for children with NF1. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Repeated presentation of a word list in a consistent order increases differences in total words recalled between those with and without Alzheimer's disease. 以一致的顺序重复呈现单词表增加了患有和没有阿尔茨海默病的人回忆单词总数的差异。
IF 3 3区 心理学
Neuropsychology Pub Date : 2026-04-16 DOI: 10.1037/neu0001090
Evan Grandoit, Seo-Eun Choi, Laura A Rabin, Roos J Jutten, Dan Mungas, Melissa Lamar, Nancy S Foldi, Beth E Snitz, C Elizabeth Shaaban, Emily H Trittschuh, Richard N Jones, Douglas Tommet, Shubhabrata Mukherjee, Phoebe Scollard, Michael L Lee, Brandon S Klinedinst, Chun Wang, Paul K Crane
{"title":"Repeated presentation of a word list in a consistent order increases differences in total words recalled between those with and without Alzheimer's disease.","authors":"Evan Grandoit, Seo-Eun Choi, Laura A Rabin, Roos J Jutten, Dan Mungas, Melissa Lamar, Nancy S Foldi, Beth E Snitz, C Elizabeth Shaaban, Emily H Trittschuh, Richard N Jones, Douglas Tommet, Shubhabrata Mukherjee, Phoebe Scollard, Michael L Lee, Brandon S Klinedinst, Chun Wang, Paul K Crane","doi":"10.1037/neu0001090","DOIUrl":"10.1037/neu0001090","url":null,"abstract":"<p><strong>Objective: </strong>Individuals with Alzheimer's disease (AD) are known to have difficulty utilizing semantic strategy to remember items from a list, such as during word list recall tasks. However, it is unclear if presenting words in the same order as compared to shuffling across trials of a list-learning test confers an advantage in terms of word recall in individuals with AD.</p><p><strong>Method: </strong>To address this issue, we leveraged data from 10,504 participants over five studies across four AD Research Centers that administered the Consortium to Establish a Registry for AD Word List Memory Test in either a standard sequence (shuffled words for each learning trial) or nonstandard sequence (unshuffled words in a consistent order for each learning trial).</p><p><strong>Results: </strong>After controlling for gender, age, years of education, apolipoprotein E gene, Clinical Dementia Rating Global Score, and composite test scores for executive functioning and language comprehension, we found that differences in word recall performance between participants with and without probable AD were larger when they were tested with the unshuffled versus standard shuffled version of the word list.</p><p><strong>Conclusions: </strong>When administered the unshuffled Consortium to Establish a Registry for AD Word List, participants without AD demonstrated a larger recall advantage compared to those with probable AD. This advantage was higher on Trial 3 (β = 0.09) compared to Trial 2 (β = 0.04), suggesting that this advantage increases with multiple immediate repetitions. Using an unshuffled word list may enhance the ability to distinguish between individuals along the AD continuum. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13155764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital maze test reveals cognitive performance patterns associated with amyloid-β and tau. 数字迷宫测试揭示了与淀粉样蛋白β和tau相关的认知表现模式。
IF 3 3区 心理学
Neuropsychology Pub Date : 2026-04-16 DOI: 10.1037/neu0001057
Talia L Robinson, Grace Del Carmen Montenegro, Jessie Fanglu Fu, Eva N Pintucci, Michael J Properzi, Dana L Penney, Randall Davis, Reisa A Sperling, Keith A Johnson, Rebecca E Amariglio, Dorene M Rentz
{"title":"Digital maze test reveals cognitive performance patterns associated with amyloid-β and tau.","authors":"Talia L Robinson, Grace Del Carmen Montenegro, Jessie Fanglu Fu, Eva N Pintucci, Michael J Properzi, Dana L Penney, Randall Davis, Reisa A Sperling, Keith A Johnson, Rebecca E Amariglio, Dorene M Rentz","doi":"10.1037/neu0001057","DOIUrl":"10.1037/neu0001057","url":null,"abstract":"<p><strong>Objective: </strong>Digital cognitive tools provide novel ways to examine subtle cognitive processes not captured with traditional measures. This is particularly useful in examining subtle cognitive changes in early Alzheimer's disease (AD) stages. Here, we evaluate a digital maze test and its association to AD biomarkers in a largely cognitively unimpaired sample.</p><p><strong>Method: </strong>A total of 221 participants in the Harvard Aging Brain Study and affiliated studies completed a digital maze test, and neuropsychological battery including the trail making test. Cortical Amyloid-β and tau burden were visualized with C¹¹Pittsburgh compound B (PiB), and [¹⁸ F]Flortaucipir. Latent patterns among maze features were explored with principal component analysis and least absolute shrinkage and selection operator regression was applied to evaluate their associations with PiB and [¹⁸ F]Flortaucipir. Multiple regression models explored both maze features and trail making test variables in models predicting AD biomarkers.</p><p><strong>Results: </strong>Principal component analysis results revealed maze performance is characterized by separate speed, path following, and impulsivity/planning components. Least absolute shrinkage and selection operator regression models revealed longer time duration (95% CI [5.31, 25.31]), greater pen-off-page time (CI [5.42, 16.81]), and pen stroke count (CI [.004, 0.021]) were associated with higher PiB. Higher pen stroke count (CI [0.003, 0.010]), and time deviating from the correct path (CI [0.0003, 0.002]) were associated with [¹⁸ F]Flortaucipir. In multiple regression models, specific maze features remained significant predictors of PiB beyond trail making test performance.</p><p><strong>Conclusion: </strong>Unique, digitally captured maze features are associated with AD pathology beyond what is seen by a traditional executive measure. This easy to administer, time-efficient digital tool provides unique information about amyloid and tau-related cognitive change. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13089301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subjective cognitive concerns and global metacognitive bias in prodromal Parkinson's and Parkinson's disease without cognitive impairment. 前驱帕金森病和无认知障碍帕金森病的主观认知关注和整体元认知偏差
IF 3 3区 心理学
Neuropsychology Pub Date : 2026-04-16 DOI: 10.1037/neu0001083
Nishaat Mukadam, Abuzar Mahmood, Alice Cronin-Golomb, Joseph DeGutis
{"title":"Subjective cognitive concerns and global metacognitive bias in prodromal Parkinson's and Parkinson's disease without cognitive impairment.","authors":"Nishaat Mukadam, Abuzar Mahmood, Alice Cronin-Golomb, Joseph DeGutis","doi":"10.1037/neu0001083","DOIUrl":"https://doi.org/10.1037/neu0001083","url":null,"abstract":"<p><strong>Objective: </strong>Subjective cognitive decline is common in persons with Parkinson's disease (PwPD) and prodromal PD (proPD) and predicts objective cognitive decline. Subjective concerns may reflect enhanced sensitivity to cognitive changes or negative global metacognitive biases (general underconfidence, not task specific) related to depression or anxiety. We evaluated the presence and predictors of metacognitive awareness, the self-assessment of one's cognitive abilities, in PwPD and proPD.</p><p><strong>Method: </strong>Data from 468 PwPD, 817 proPD, and 75 healthy control adults were drawn from the Parkinson's Progressive Markers Initiative database. Measures included subjective- and objective-cognitive composites. We assessed metacognitive sensitivity (the relation between subjective and objective cognition) and the relation between metacognitive bias (subjective minus objective cognition) and depression, anxiety, demographics, and PD-related variables. Significant associations were included in linear regression models separately for PwPD and proPD. To assess effect consistency, we examined baseline versus Time 2 difference scores in a subsample who had the same measures 12 months later.</p><p><strong>Results: </strong>ProPD (ρ = .13), but not PwPD (ρ = .08), showed significant metacognitive sensitivity. More negative metacognitive bias was predicted by age, education, depression, and trait anxiety in PwPD (<i>R</i>² = .17) and proPD (<i>R</i>² = .24). The relation between anxiety and negative metacognitive bias was consistent over a 12-month period for PwPD (ρ = -.18; <i>R</i>² = .05).</p><p><strong>Conclusions: </strong>Negative metacognitive bias, predicted by depression and anxiety, may underlie subjective cognitive concerns in PwPD and proPD, with implications for treatment. These findings support using global approaches to metacognitive awareness, which are likely more accurate measures of daily cognitive awareness than are task-specific measures. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The unity and diversity of executive functions across adulthood in a diverse Brazilian sample with varying educational attainment. 不同教育程度的巴西成年人执行功能的统一性和多样性。
IF 3 3区 心理学
Neuropsychology Pub Date : 2026-04-16 DOI: 10.1037/neu0001085
Sabine Pompeia, Tâmara P Taporoski, Isis Angélica Segura, Luz Marina Gómez, Hugo Cogo-Moreira, Andrea Roseli Vançan Russo Horimoto, Alexandre da Costa Pereira, Homero Vallada, André Brooking Negrão
{"title":"The unity and diversity of executive functions across adulthood in a diverse Brazilian sample with varying educational attainment.","authors":"Sabine Pompeia, Tâmara P Taporoski, Isis Angélica Segura, Luz Marina Gómez, Hugo Cogo-Moreira, Andrea Roseli Vançan Russo Horimoto, Alexandre da Costa Pereira, Homero Vallada, André Brooking Negrão","doi":"10.1037/neu0001085","DOIUrl":"https://doi.org/10.1037/neu0001085","url":null,"abstract":"<p><strong>Objective: </strong>Executive functions (EFs) are a set of cognitive abilities associated with many social and clinical outcomes that are believed to be sensitive to culture, age, and educational attainment. Yet, this was determined using EF theoretical models and tests developed for highly educated young adults, so it may not apply to more diverse samples.</p><p><strong>Method: </strong>A community sample from Brazil (Baependi Heart Study cohort: <i>N</i> = 1,253; 753 females), in which age (18-88 years) and schooling (0-23 years) varied widely, was assessed based on a popular theoretical model of EF (the unity and diversity EF framework), which describes the pattern of interassociations of three specific types of EFs (inhibition, shifting, and updating). To this end, we employed a short, nonautomated, open-access EF test battery adapted for use in samples with varying ages and educational attainment that included EF indicators obtained from three tasks (Plus-Minus, Trail Making, and Random Number Generation tasks).</p><p><strong>Results: </strong>Using confirmatory factor analyses, we found a good-fitting three-correlated factor solution confirming the fractionation and interassociation of the three EF domains, which was invariant (except for one of eight indicators) to age, schooling, and sex. More years of schooling were related to higher latent traits in all domains and older age to worse shifting, and women scored lower in latent shifting and inhibition.</p><p><strong>Conclusions: </strong>The unity-diversity EF framework can be determined across adulthood in diverse samples with tasks adapted for these populations. Building upon our findings may expand a theory-oriented investigation of sociocultural, demographic, and clinical factors that influence EFs. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monetary savings and neuropsychological functioning in older adults without dementia. 无痴呆老年人的货币储蓄和神经心理功能。
IF 3 3区 心理学
Neuropsychology Pub Date : 2026-04-09 DOI: 10.1037/neu0001082
Cassidy P Molinare, Daisy T Noriega-Makarskyy, Jordan T Williams, Emma Oyen, Paige Kim, Jenna Axelrod, S Duke Han
{"title":"Monetary savings and neuropsychological functioning in older adults without dementia.","authors":"Cassidy P Molinare, Daisy T Noriega-Makarskyy, Jordan T Williams, Emma Oyen, Paige Kim, Jenna Axelrod, S Duke Han","doi":"10.1037/neu0001082","DOIUrl":"10.1037/neu0001082","url":null,"abstract":"<p><strong>Objective: </strong>Socioeconomic status has been associated with cognitive functioning across the lifespan, but specific neuropsychological and economic components were not considered by previous studies. Here, we investigated monetary savings as a measure of socioeconomic status and its association with performance across multiple neuropsychological measures in older adults without dementia.</p><p><strong>Method: </strong>Participants included 111 individuals (<i>M</i><sub>age</sub> = 68.5, <i>SD</i> = 7.2; <i>M</i> years of education = 16.7, <i>SD</i> = 2.2; 73% female; 75.7% White) recruited from the greater Los Angeles area. Demographic data, household income, and combined monetary savings across checking and savings accounts were self-reported through a questionnaire. Participants completed cognitive measures from the National Alzheimer's Coordinating Center Uniform Data Set, Version 3, and the National Institutes of Health Toolbox Cognitive Battery, Version 2. Multiple linear regression analyses were conducted to evaluate associations between monetary savings and each cognitive measure. All analyses controlled for age, sex, years of education, and income.</p><p><strong>Results: </strong>Greater monetary savings were associated with greater performance on a fluid cognition domain (<i>b</i> = 1.18, 95% CI [0.10, 2.25], <i>p</i> = .032), and more specifically on an inhibitory control task (<i>b</i> = 0.98, 95% CI [0.25, 1.70], <i>p</i> = .009). Post hoc analyses demonstrated that this effect was driven by individuals with above-median savings <i>(b</i> = 2.02, 95% CI [0.04, 3.99], <i>p</i> = .045).</p><p><strong>Conclusions: </strong>Our findings suggest that greater inhibitory control is associated with greater monetary savings and that this relationship is more salient among older individuals with relatively high savings. Further research is needed to determine the underlying mechanisms of this association. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13078639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147645938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive health on the fingertips: Fine motor deficiencies for assessing the risk of mild cognitive impairment in the aging adults. 指尖的认知健康:精细运动缺陷对老年人轻度认知障碍风险的评估。
IF 3 3区 心理学
Neuropsychology Pub Date : 2026-04-06 DOI: 10.1037/neu0001074
Yejing Zhao, Jie Zhang, Yanyan Zhao, Ying Yuan, Ji Shen, Hongyu Peng, Jing Li
{"title":"Cognitive health on the fingertips: Fine motor deficiencies for assessing the risk of mild cognitive impairment in the aging adults.","authors":"Yejing Zhao, Jie Zhang, Yanyan Zhao, Ying Yuan, Ji Shen, Hongyu Peng, Jing Li","doi":"10.1037/neu0001074","DOIUrl":"10.1037/neu0001074","url":null,"abstract":"<p><strong>Objective: </strong>Mild cognitive impairment (MCI) represents a critical prodromal stage associated with Alzheimer's disease and other age-related neurocognitive conditions in middle-old aging adults, yet research exploring its association with fine motor skill deficits remains relatively limited. This study explores the specific characteristics of fine motor function in middle-old aging adults with MCI using the latest wearable inertial motion capture technology.</p><p><strong>Method: </strong>A computerized system with wearable inertial motion capture technology captured and assessed fine motions. The least absolute shrinkage and selection operator-based machine learning algorithm was utilized to construct a nomogram. The discriminatory ability of the model was determined by calculating the area under the curve. Decision curve analysis, clinical impact curve analysis, and bootstrap validation were used to evaluate and validate the stability of models.</p><p><strong>Results: </strong>A total of 289 participants aged ≥50 were recruited, of which 140 participants experienced MCI. Compared with the control group, patients with MCI showed significantly poorer fine motor performance in hand function assessment tasks. Spearman correlation analysis revealed a stronger correlation between fine motor function and visuospatial/executive function. A multivariable nomogram model based on fine motion parameters showed satisfactory discrimination, with an area under the curve of .773. Decision curve analysis, clinical impact curve analysis, and bootstrap validation demonstrated the good clinical utility and stability of the model.</p><p><strong>Conclusions: </strong>Poor motor functioning was associated with MCI status. The nomogram model, based on fine motion parameters, demonstrated moderate discriminative performance in assessing the risk of MCI, serving as a valuable clinical supplement. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147623535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of everyday executive functioning in children and adolescents treated for childhood noncentral nervous system solid tumor. 儿童和青少年非中枢神经系统实体瘤治疗的日常执行功能评估。
IF 3 3区 心理学
Neuropsychology Pub Date : 2026-04-06 DOI: 10.1037/neu0001060
Zoé Barrault, Arnaud Roy, Hugo Câmara-Costa, Audrey Longaud, Virginie Kieffer, Jacques Grill, Nathalie Gaspar, Véronique Minard-Collin, Brice Fresneau, Charlotte Rigaud, Léa Guerrini-Rousseau, Samuel Abbou, Pablo Berlanga, Claudia Pasqualini, Stephanie Bolle, Christelle Dufour, Mathilde Chevignard
{"title":"Assessment of everyday executive functioning in children and adolescents treated for childhood noncentral nervous system solid tumor.","authors":"Zoé Barrault, Arnaud Roy, Hugo Câmara-Costa, Audrey Longaud, Virginie Kieffer, Jacques Grill, Nathalie Gaspar, Véronique Minard-Collin, Brice Fresneau, Charlotte Rigaud, Léa Guerrini-Rousseau, Samuel Abbou, Pablo Berlanga, Claudia Pasqualini, Stephanie Bolle, Christelle Dufour, Mathilde Chevignard","doi":"10.1037/neu0001060","DOIUrl":"https://doi.org/10.1037/neu0001060","url":null,"abstract":"<p><strong>Objective: </strong>Few studies have documented executive functions (EFs) following treatment of childhood noncentral nervous systems (non-CNS) solid tumor although treatments administered for several months or even a year during active brain development could affect EF development. The aims of this study were to explore everyday life executive complaints and associated factors.</p><p><strong>Method: </strong>EFs were assessed using parent form of the Behavior Rating Inventory of Executive Function in a large sample of participants diagnosed with a non-CNS solid tumor (<i>n</i> = 253).</p><p><strong>Results: </strong>The study sample comprised 253 patients (139 boys [55%]; mean age at diagnosis 6.12 years [<i>SD</i> = 4.18] years, mean age at assessment 11.65 years [<i>SD</i> = 3.21], 17 [7%] with a history of developmental delay or learning disability before cancer). Parental education level was medium-low (i.e., <12 years of formal education) in 94 families (37%). Mean Behavior Rating Inventory of Executive Function <i>T</i>-scores were in the normative range, but significantly elevated compared to norms across all three composite indices and most clinical scales (all <i>p</i> < .001), with small effect sizes (Cohen's 0.20 < <i>d</i> ≤ 0.30). Thirty-eight (15%) participants evidenced global executive composite scores in the clinical range (<i>T</i> ≥ 65). Executive complaints were significantly more frequent in boys, in older participants at assessment, in those with longer time since diagnosis, and in those with a history of developmental delay/learning disabilities. Clinically significant global executive composite scores were also associated with greater need for school support and ongoing rehabilitation at the time of assessment.</p><p><strong>Conclusions: </strong>Our results suggest significant, albeit mild parent-reported EF impairments following treatment of childhood non-CNS tumor. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147623532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurocognitive and behavioral predictors of the simple view of reading in clinically evaluated children with and without ADHD. 临床评估有或无ADHD儿童简单阅读观的神经认知和行为预测因子。
IF 3 3区 心理学
Neuropsychology Pub Date : 2026-03-26 DOI: 10.1037/neu0001078
Alissa M Cole-Olsen, Fatou Gaye, Julia O Obi, Christian J Padron, Michael J Kofler
{"title":"Neurocognitive and behavioral predictors of the simple view of reading in clinically evaluated children with and without ADHD.","authors":"Alissa M Cole-Olsen, Fatou Gaye, Julia O Obi, Christian J Padron, Michael J Kofler","doi":"10.1037/neu0001078","DOIUrl":"10.1037/neu0001078","url":null,"abstract":"<p><strong>Objective: </strong>Children with attention-deficit/hyperactivity disorder (ADHD) often exhibit difficulties across multiple reading domains. The \"simple view of reading\" model posits that reading comprehension skills-both for children with and without ADHD-can be understood by skills in two components: decoding and language comprehension. At the same time, research suggests that weaknesses in neurocognitive abilities, along with behavioral symptoms of ADHD, are closely linked to reading difficulties in this population. However, the most parsimonious set of neurocognitive and behavioral predictors of reading comprehension, and the pathways through which associations are conveyed, remains unclear.</p><p><strong>Method: </strong>The present study employed structural equation modeling to comprehensively examine neurocognitive and behavioral predictors of reading skills in a clinically evaluated sample of 396 children with and without ADHD (<i>M</i><sub>age</sub> = 10.26, <i>SD</i> = 1.39; 172 girls; 68.9% White not Hispanic or Latino).</p><p><strong>Results: </strong>Results revealed that working memory and fluid intelligence were the strongest neurocognitive predictors of reading skills and inattention and hyperactive/impulsive symptoms each predicted reading in the behavioral model. Consistent with the simple view of reading, associations between neurocognitive or behavioral predictors and reading comprehension were conveyed via decoding and language comprehension. When examining neurocognitive and behavioral predictors together, working memory and fluid intelligence predicted ADHD symptoms and reading skills, whereas ADHD symptoms no longer predicted reading skills, suggesting that neurocognitive weaknesses may help explain the link between inattention and reading.</p><p><strong>Conclusions: </strong>These findings highlight the role of neurocognitive weaknesses for comprehensively understanding reading difficulties in clinically evaluated children with and without ADHD. (PsycInfo Database Record (c) 2026 APA, all rights reserved).</p>","PeriodicalId":19205,"journal":{"name":"Neuropsychology","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13023043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147513489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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