Neurourology and Urodynamics最新文献

{"title":"β₃-Adrenoceptor Agonist Effects on the Urinary Bladder Beyond Detrusor Relaxation.","authors":"Martin C Michel, Ebru Arioglu-Inan, Martin Hennenberg","doi":"10.1002/nau.70043","DOIUrl":"10.1002/nau.70043","url":null,"abstract":"<p><strong>Aims: </strong>β₃-Adrenoceptor agonists such as mirabegron or vibegron reach pharmacokinetic steady-state within a few days. However, maximum improvements in symptoms of the overactive bladder syndrome are reached at time points later than 4 weeks, that is, detrusor smooth muscle relaxation cannot fully explain clinical effects. Therefore, we review mechanistic studies that have administered such drugs for longer periods of time.</p><p><strong>Methods: </strong>Narrative review.</p><p><strong>Results: </strong>The limited data indicates that β₃-adrenoceptor agonists reduce bladder fibrosis and hypertrophy and may induce cell proliferation. On the other hand, limited data also indicate that detrusor relaxation responses can partly desensitize with prolonged agonist exposure, possibly off-setting effects on fibrosis and hypertrophy.</p><p><strong>Conclusions: </strong>Further long-term studies with β₃-adrenoceptor agonists are needed to clarify the role of such processes in clinical improvement of patients with overactive bladder syndrome occurring at time points later than 4 weeks after initiation of treatment.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":"1498-1502"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Deep Learning and Numerical Analysis for Bladder Outflow Obstruction and Detrusor Underactivity Diagnosis in Men: A Novel Urodynamic Evaluation Scheme.","authors":"Wouter van Dort, Thomas R F van Steenbergen, Peter F W M Rosier","doi":"10.1002/nau.70049","DOIUrl":"10.1002/nau.70049","url":null,"abstract":"","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":"1521-1522"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on \"Transvaginal Electrical Stimulation for Treatment of Overactive Bladder Without Incontinence: A Pilot Cross-Over Clinical Trial\".","authors":"Venkata Dileep Kumar Veldi, Rachana Mehta, Ranjana Sah","doi":"10.1002/nau.70062","DOIUrl":"10.1002/nau.70062","url":null,"abstract":"","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":"1523-1524"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144111148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Urinary Microbiome in Women Using Single-Use Versus Reusable Catheters for Intermittent Catheterization: An Exploratory Substudy of the COMPaRE Trial.","authors":"Felice Emanuela Espèrance van Veen, Zhaleh Esmi Serkani, Sophie Berendsen, Robert Kraaij, Lonneke Bode, John Philip Hays, Jeroen Ronald Scheepe, Bertil Freddo Maarten Blok","doi":"10.1002/nau.70119","DOIUrl":"10.1002/nau.70119","url":null,"abstract":"<p><strong>Aims: </strong>To characterize the urinary microbiome in women performing clean intermittent self-catheterization (CISC) and explore microbial changes associated with transitioning from single-use to reusable catheters.</p><p><strong>Methods: </strong>This microbiome study of the COMPaRE trial included female CISC patients with urinary retention randomized to either single-use or reusable catheters. Self-catheterized urine samples were collected at baseline and Week 6 for standard culture and 16S rRNA microbiome analysis.</p><p><strong>Results: </strong>A total of 28 patients (12 reusable, 16 single-use) were included, with a median age of 48 years (IQR 32-60); 67.9% had neurogenic lower urinary tract dysfunction. Escherichia-Shigella (36.3%) and Lactobacillus (22.8%) were the most prevalent genera. PERMANOVA identified significant effects of age (p = 0.003), menopausal status (p < 0.001), and catheterization cause (p = 0.003) on microbiome composition. Transitioning to reusable catheters was associated with significant reductions in Escherichia-Shigella (p < 0.001) and Aerococcus (p < 0.001), and increases in Veillonella (p < 0.001) and Finegoldia (p < 0.001). No significant changes were observed in urine culture results (p = 0.250), alpha diversity as measured by the Shannon index (p = 0.862), or beta diversity as assessed by Bray-Curtis distance (p = 0.096).</p><p><strong>Conclusions: </strong>Escherichia-Shigella and Lactobacillus were the most abundant genera in the urinary microbiome of women performing CISC. Age, menopausal status, and catheterization cause significantly influenced microbiome composition. Although specific microbial shifts were observed following transition to reusable catheters, no significant changes in overall microbial diversity were detected. Larger, well-powered studies are needed to validate these results and assess their potential clinical implications.</p><p><strong>Trial registration: </strong>Clinical Trial RegistrationNL-OMON54700/NL8296.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":"1474-1483"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144708262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress Urinary Incontinence Treatment With Microablative Radiofrequency, Pelvic Floor Muscle Training or Combination of Both Techniques in Climacteric Women: Randomized Controlled Trial 6-Month Follow-Up.","authors":"Anna Lygia B Lunardi, Cassia R T Juliato, Helena Slongo, Helymar C Machado, Cassio L Z Riccetto","doi":"10.1002/nau.70096","DOIUrl":"10.1002/nau.70096","url":null,"abstract":"<p><strong>Introduction: </strong>Fractional microablative radiofrequency (FMRF) has been used as an alternative to conservative treatments such as pelvic floor muscle training (PFMT). However, evidence supporting its effectiveness compared to or alongside these treatments is lacking.</p><p><strong>Objective: </strong>To compare the effects of FMRF, PFMT, and their combination (PFMT + FMRF) on urinary symptoms and pelvic floor function in climacteric incontinent women over a 6-month follow-up.</p><p><strong>Methods: </strong>This randomized, prospective, and controlled clinical trial, blinded to the investigator, included women aged 45-65 years with stress urinary incontinence, divided into three treatment groups: PFMT (12 weekly sessions), FMRF (3 monthly applications), and PFMT + RF. Urinary symptoms were assessed using the International Consultation on Incontinence Questionnaire Urinary Incontinence-Short Form (ICIQ UI-SF) and a 1-h pad test. Pelvic floor function was evaluated using PERFECT and perineometry, along with treatment satisfaction. ANOVA was used to compare the results.</p><p><strong>Results: </strong>The study included 117 women (39 in each group), with similar clinical and sociodemographic characteristics. SUI assessed by the ICIQ-SF UI showed significant improvement in all groups posttreatment, maintained at follow-up (p < 0.001), with greater variation in the PFMT + RF group (p = 0.002). The 1-h pad test also improved in all groups, with effects lasting 6 months. Muscle function assessment showed similar Power improvement across all groups (p < 0.001). Endurance improved posttreatment in the PFMT group, with a slight decline at 6 months (p = 0.027), while the FMRF + PFMT group maintained their improvement (p < 0.001). Repetition improved in the PFMT and RF + PFMT groups (p < 0.001; p = 0.001). Fast contractions increased in all groups, with significant group x time interaction (p = 0.002). Only the PFMT group showed improvement in Perineometry. At 6 months, 22.61% were very satisfied, 46.42% were satisfied, 10.71% reported being cured, and 69.04% reported symptom improvement.</p><p><strong>Conclusion: </strong>The combination of techniques (RF + PFMT) showed superior results for treating UI in climacteric women over 6 months, promoting improvement in urinary symptoms and pelvic floor function compared to isolated treatments.</p><p><strong>Trial registration: </strong>The trial is registered as REBEC (Registro Brasileiro de Ensaios Clínicos; Brazilian Registry of Clinical Trials) under number RBR-9v3q33.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":"1412-1424"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144541594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Related Outcomes for Interstitial Cystitis/Bladder Pain Syndrome Recommendations for Clinical Trials and General Urology Practice.","authors":"Byron Hayes, Mary Namugosa, Robert J Evans, Sakineh Hajebrahimi, Dick Janssen, Claudia King, Sanjay Pandey, J Curtis Nickel","doi":"10.1002/nau.70107","DOIUrl":"10.1002/nau.70107","url":null,"abstract":"<p><strong>Introduction: </strong>The goal of this committee of the Interstitial Cystitis/Bladder Pain (IC/BPS) Consensus Group was to address the use of patient related outcomes (PROs) in IC/BPS.</p><p><strong>Methods: </strong>Priority areas of concern and related PICO (Population, Intervention, Comparison, Outcome) questions were addressed based on literature review, committee discussion and consensus group feedback. Consensus recommendations were developed regarding PROs and PRO Measures (PROMs) for the critical PICO questions.</p><p><strong>Results: </strong>PICO questions addressed 4 critical areas of concern: PROs, clinical trial primary endpoints, secondary endpoint PROMs and questionnaires for general practice management. The committee made 12 recommendations regarding outcomes in IC/BPS research and clinical practice.</p><p><strong>Discussion: </strong>The most important recommendation was the unmet need to develop and validate a better IC/BPS specific PRO, based on unbiased patient qualitative research methodology. At the present time, the Numerical Rating/VAS pain scales, voiding diaries and global response assessment are recommended for primary endpoint outcomes in clinical trials. The suggested composite IC/BPS specific PROM is the Genito Urinary Pain Index (GUPI) while the Interstitial Cystitis Symptom Index/Problem Index can be used for trial comparisons. If appropriate, generic PROMs that describe and measure pain, quality of life, sexual, and psychosocial parameters are suggested. Until a validated PRO is developed, the NIH GUPI or the Pain Urinary Frequency (PUF) questionnaire provides reasonable clinical evaluation of patients in standard urology practice.</p><p><strong>Conclusion: </strong>PROMs are currently available for use in clinical trials and general practice, but more research is required to create better IC/BPS PRO-based outcome measures.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":"1455-1465"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toileting and Bladder Health in the Gig Economy.","authors":"Leah Chisholm, Andria N Li, Parisa Samimi, Melissa R Kaufman, Roger R Dmochowski, William Stuart Reynolds, Elisabeth M Sebesta","doi":"10.1002/nau.70122","DOIUrl":"10.1002/nau.70122","url":null,"abstract":"<p><strong>Objective: </strong>An increasing percentage of the population participates in the \"gig economy\" - short-term work through online applications. This study often requires continuous travel without reliable restroom access. We aimed to assess toileting behaviors and bladder health in gig economy workers.</p><p><strong>Methods: </strong>Adult gig workers were electronically recruited using ResearchMatch. Participants completed validated questionnaires assessing bladder health, lower urinary tract symptoms (LUTS), toileting behaviors, and information about gig economy work. Toileting behaviors, coping strategies, and aspects of their work were compared between those with and without difficulty finding restrooms while at work.</p><p><strong>Results: </strong>Of 527 gig workers who participated, 80 (15%) reported difficulty finding restrooms while working. Demographics and type of gig work were similar between groups. Gig workers with difficulty finding restrooms reported higher rates of unhealthy toileting behaviors and coping strategies, such as fluid restricting and delayed voiding. While at work, those with difficulty finding restrooms experienced more severe LUTS. While difficulty finding restrooms was not associated with any psychosocial or demographic factors, it was associated with worsening of urinary symptoms since starting gig work.</p><p><strong>Conclusions: </strong>Gig workers overall report engaging in unhealthy toileting behaviors and coping strategies at work. Gig workers with difficulties in accessing restrooms while working report higher severity of irritative LUTS and are more likely to demonstrate poor toileting habits, which may further exacerbate underlying bladder conditions. Further research is needed to better understand the long-term associations between bladder health, restroom access and employment in the gig economy.</p><p><strong>Clinical trial registration: </strong>This study does not require clinical trial registration as no randomized clinic trial was performed.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":"1439-1447"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144732449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Clinical Significance of the Subtypes of Detrusor Overactivity: A Systematic Review.","authors":"Manisha Teji, Nicholas Raison, Nicholas Faure-Walker","doi":"10.1002/nau.70110","DOIUrl":"10.1002/nau.70110","url":null,"abstract":"<p><strong>Introduction: </strong>Detrusor overactivity (DO) is the \"occurrence of detrusor contraction(s) during filling cystometry\" [7] and can be \"phasic\" or \"terminal\" [26]. The aim of this systematic review was to establish whether there is any clinical significance between the different subtypes of DO in terms of demographics, underlying pathophysiology, symptoms, other urodynamic parameters and response to treatment.</p><p><strong>Methods: </strong>A systematic search was performed using PubMed, Cochrane, MEDLINE, Web of Science and EMBASE databases in February 2024, following the PRISMA guidelines. The Newcastle Ottawa critical appraisal tool was used to assess the risk of bias in the included studies.</p><p><strong>Results: </strong>The search identified 16 relevant studies including eight prospective and eight retrospective studies. Patients with terminal DO were found to be significantly older (p = 0.0003) and were more likely to have suffered spinal cord trauma (p = 0.04) compared to those with phasic DO. Patients with terminal DO were also found to have higher symptom scores and more likely to also suffer with incontinence than those with phasic DO. Patients with terminal DO were found to have smaller functional capacities than those with phasic DO on urodynamics. Success rates, following trans-urethral resection of the prostate (TURP), were 69.2% for patients with phasic DO and 9.5% for those with terminal DO.</p><p><strong>Conclusion: </strong>Patients with terminal DO are more likely to be older, suffer with worse symptoms, have smaller bladder capacities and respond less favourably to treatment than those with phasic DO. Future studies incorporating DO should consider analysing these two sub-types of DO as separate clinical entities.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":"1484-1490"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144554028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing the Impact of a New β3 Adrenergic Agonist on Chorioretinal and Peripapillary Vessel Density.","authors":"Meryem Feyza Cicek, Abdullah Ağın, Burcu Yakut, Ata Baytaroglu, Mucahit Gelmis, Faruk Ozgor, Feyza Onder","doi":"10.1002/nau.70108","DOIUrl":"10.1002/nau.70108","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the impact of mirabegron, a novel β3 adrenoceptor agonist employed for the treatment of overactive bladder (OAB), on the optic nerve head and chorioretinal vasculature using optical coherence tomography angiography (OCTA).</p><p><strong>Materials and methods: </strong>Fifty eyes of 25 patients who used a 50 mg tablet of mirabegron once daily for OAB were included in this prospective study. OCTA was performed at 6 × 6 mm of the macula and 4.5 × 4.5 mm of the optic disc. Retinal nerve fiber layer (RNFL) thickness, macular ganglion cell complex(mGCC) thickness, foveal avascular zone (FAZ), choriocapillaris (CC) flow area, CC vessel flow density (VFD), optic nerve head, and macula vessel densities were evaluated before the treatment and 2 months after treatment initiation.</p><p><strong>Results: </strong>RNFL, mGCC in all quadrants, and FAZ were similar before and 2 months after treatment started point. In optic nerve head vessel density measurements, whole image vessel density (wiVD), mean ppVD (peripapillary vessel density), inferior ppVD, and ppVD in nasal superior, inferior nasal, and temporal superior quadrants measurements following mirabegron treatment were found to be lower than the pretreatment measurements (p < 0.05). Following treatment, wiVD decreased by 1.2% (Cohen's d = 0.26) and mean ppVD decreased by 0.8% (Cohen's d = 0.25), indicating a small effect size. All macular parameters were similar before and 2 months after treatment. No statistically differences were observed in terms of CC parameters.</p><p><strong>Conclusion: </strong>The reduction in optic nerve head vascularity parameters following mirabegron treatment contributes to understanding the impact of β3-AR agonists, which are being investigated as a therapeutic target for treating retinal vascular diseases. These findings may provide valuable insight into the systemic vascular effects of β3-adrenergic agonists and could be relevant in shaping therapeutic strategies aimed at preserving optic nerve head perfusion, particularly in patients at risk of vascular compromise. Further studies with larger cohorts and longer follow-up are needed to validate these preliminary findings.</p><p><strong>Trial registration: </strong>This study is a prospective observational study and does not qualify as a clinical trial. Therefore, registration is not required.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":"1503-1511"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144497547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Autonomic Control Reflects Sympathovagal Changes Associated With Withholding Urination.","authors":"Ahmad Alabdo, Başak Oflazoğlu, Mehmet Mustafa Kuş, Pınar Çakan, Seda Uğraş, Sedat Yıldız","doi":"10.1002/nau.70105","DOIUrl":"10.1002/nau.70105","url":null,"abstract":"<p><strong>Introduction: </strong>Increased volume of the urinary bladder causes urge to urinate and constricts the sphincter by increasing the tonus of the sympathetic nervous system (SNS). Activity of the autonomic nervous system (or sympatho-vagal balance) can be assessed by heart rate variability (HRV). Current study aimed to test in healthy young male participants whether HRV technique reflects increased sympathovagal balance during bladder distention as revealed by strong urge to urinate.</p><p><strong>Materials and methods: </strong>A total of young and apparently healthy 11 males agreed to participate to the current study. They were asked to provide 5-min continuous electrocardiogram (ECG) recordings in supine position for determination of HRV on two occasions, i.e. before and approximately for 3½ hours after withholding urination. HRV parameters included heart rate (HR, per min), total power (TP, ms²), and standard deviation of RR intervals (SDNN, ms); percentage of successive RR intervals that were different ≥ 50 ms (pNN50), low frequency (LF) and high frequency (HF) bands and their normalized units (LFnu and HFnu, respectively) and their ratios (LF/HF). Half of the students provided samples on both occasions and those data were compared by paired t-test following log10 transformation.</p><p><strong>Results: </strong>Withholding urination did not change HR (from 80.0 ± 4.1 to 84.5 ± 3.1 per min, p = 0.135) but decreased total power (from 2692 ± 802 to 1605 ± 357 ms², p = 0.008), SDNN (from 50.4 ± 5.8 to 38.7 ± 3.8 ms, p = 0.007) and pNN50 (from 15.6 ± 3.3 to 5.9 ± 2.6%, p = 0.016) and increased LFnu (from 57.3 ± 5.3 to 65.1 ± 4.5, p = 0.029) and LF/HF ratio (from 1.77 ± 0. 73 to 2.42 ± 0.47, p = 0.047).</p><p><strong>Conclusions: </strong>Increased LF/HF together with decreased SDNN and pNN50 suggest that HRV successfully reflects increased sympathetic tonus over the parasympathetic to help accommodate the urine in the bladder. Moreover, it seems that HRV can be used to assess sympathovagal changes non-invasively during voiding. Additionally, it appears that in all HRV measurements, participants should not have postponed their urination during recording.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":"1512-1520"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144507071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}