Neurourology and Urodynamics最新文献

{"title":"Rising Prevalence of Urinary Incontinence and Nocturia Amid the COVID-19 Pandemic.","authors":"Weilong Lin, Hao Huang, Yuan Ou, Bingliang Chen, Tao Du, Yongyang Wu, Hai Huang","doi":"10.1002/nau.70071","DOIUrl":"https://doi.org/10.1002/nau.70071","url":null,"abstract":"<p><strong>Background: </strong>Urinary incontinence (UI) and nocturia are common lower urinary tract symptoms (LUTS) that significantly affect quality of life. The COVID-19 pandemic has introduced behavioral, psychological, and physiological disruptions that may have exacerbated the prevalence of these conditions. Additionally, these changes may also be influenced by long-term sequelae of COVID-19 infection or other concurrent factors. However, large-scale investigations into these trends are limited.</p><p><strong>Methods: </strong>Data from the National Health and Nutrition Examination Survey (NHANES) between 2017 and 2023 were used to analyze the prevalence of LUTS, including stress urinary incontinence (SUI), urgency urinary incontinence (UUI), mixed urinary incontinence (MUI), and nocturia, before (2017-2020) and during the pandemic (2021-2023). Age-adjusted prevalence trends were analyzed overall and by sex and race/ethnicity. Sensitivity analysis included data from 2013 to 2016 to differentiate natural trends from pandemic-related impacts.</p><p><strong>Results: </strong>The prevalence of SUI, UUI, MUI, and nocturia significantly increased during the pandemic compared to pre-pandemic levels (p < 0.0001). SUI rose from 24.89% to 29.65%, UUI from 20.80% to 28.65%, MUI from 9.17% to 16.83%, and nocturia from 26.96% to 34.78%. These trends were consistent across sexes and racial groups. Sensitivity analysis confirmed that these increases exceeded natural trends, suggesting a potential pandemic-related effect.</p><p><strong>Conclusion: </strong>This study reveals a significant rise in the prevalence of LUTS, including SUI, UUI, MUI, and nocturia, during the COVID-19 pandemic. Further research is needed to determine whether these changes stem from the direct physiological effects of COVID-19 infection or are influenced by broader pandemic-related factors such as lifestyle changes, healthcare disruptions, and psychological stress.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Methodology in Acupuncture for Managing Interstitial Cystitis/Bladder Pain Syndrome: A Scoping Review.","authors":"Miguel Ángel Infantes Rosales, Ángeles Mesías Pesqueira, Astrid Castellanos Díaz, Esther Díaz Mohedo","doi":"10.1002/nau.70061","DOIUrl":"https://doi.org/10.1002/nau.70061","url":null,"abstract":"<p><strong>Background: </strong>Acupuncture and moxibustion are being explored as complementary therapies with promising potential in managing interstitial cystitis/bladder pain syndrome (IC/BPS). While some studies indicate possible benefits, their scientific basis and clinical efficacy remain subjects of debate, partly due to methodological flaws in study designs involving acupuncture and related modalities, which warrant further attention and discussion. The main objective is to analyze and evaluate the research methodologies used in existing literature on acupuncture for managing IC/BPS, providing insight into the methodological challenges and opportunities in this field.</p><p><strong>Materials and methods: </strong>National Library of Medicine (PubMed), Allied and Complementary Medicine Database (AMED), Cochrane Library, Excerpta Medica database (EMBASE), Web of Sciences (WOS), Medical Literature Analysis and Retrieval System Online (MEDLINE), Cumulated Index in Nursing and Allied Health Literature (CINAHL), Scopus, SPORTDiscus, Epistemonikos, and Physiotherapy Evidence Database (PEDro) were searched from their inception to August 2024. Data were extracted based on the study designs, primary outcome measures, adverse events (AEs), and participants' subjective views.</p><p><strong>Results: </strong>All the experimental studies (27.3%, 6 of 22) were randomized controlled trials (RCTs), but only 2 full texts were accessible. Of the 4 RCTs, 3 involved rats. Observational research (50%) included case reports (27.3%), cohort studies (9.1%), and theoretical studies (4.5%). Additionally, reviews (22.7%) were included. The main languages were English (77.3%), Chinese (13.6%), Japanese (4.5%), and Russian (4.5%). The most frequently reported outcome was pain, followed by quality-of-life impact (symptom burden), urinary frequency and urgency, nocturia, and bladder capacity. AEs were reported in only 5 articles, all of which concluded that these effects were not significant and that acupuncture could be considered a safe and relatively noninvasive technique. One review found a risk of 1 AE/76 000 patients, with the most common side effects being minor, such as bleeding or bruising.</p><p><strong>Conclusion: </strong>Current evidence on acupuncture for interstitial cystitis is limited in quality, with studies often compromised by biases, small sample sizes, and lack of standardized protocols. Acupuncture is frequently part of multimodal treatments, aligning with Traditional Chinese Medicine's holistic approach to balance physical, mental, and emotional health. More high-quality experimental research is needed, focusing on standardized protocols and participant experiences to better evaluate its efficacy and safety.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spinal Cord Lower Urinary Tract Control in Humans.","authors":"Betsy H Salazar, Charles M Mazeaud, Kristopher A Hoffman, Argyrios Stampas, Rose Khavari","doi":"10.1002/nau.70059","DOIUrl":"https://doi.org/10.1002/nau.70059","url":null,"abstract":"<p><strong>Background and objective: </strong>Although there have been significant advancements in functional magnetic resonance imaging (fMRI) studies that have enhanced our understanding of brain control over bladder function in humans, a notable gap still exists in exploring spinal cord involvement in real-time. The objective of this study was to develop and validate an fMRI protocol to assess innate spinal cord activity in humans within regions associated with bladder function.</p><p><strong>Methods: </strong>Twenty healthy adult participants 9 men, 11 women underwent functional magnetic resonance imaging (fMRI) of the spinal cord during implementation of a natural bladder filling protocol and simulated bulbocavernosus reflex (sBCR). Anatomical images were obtained, followed by resting-state and task-based fMRI assessments during both full and empty bladder states. Functional spinal neuroimaging data were analyzed using a custom pipeline comprised of Spinal Cord Toolbox, FSL, and MATLAB scripts for preprocessing and analysis.</p><p><strong>Key findings and limitations: </strong>Our preliminary findings revealed activation in 15 participants (7 men, 8 women), exhibiting diverse patterns of activity across the T10-S5 neuronal segments during task-fMRI sessions conducted with both empty and full bladder conditions during sBCR. The identified activated regions included sympathetic (T10-L2), parasympathetic (S2-S4), and somatic nuclei (S2-S4), previously implicated in facilitating lower urinary tract (LUT) control. Notably, our preliminary findings suggest that sex differences may influence these activation patterns, though further investigation and second-level analysis are warranted to confirm this observation.</p><p><strong>Conclusions: </strong>Although preliminary, our findings demonstrate, for the first time, the efficacy of our fMRI protocol in detecting task-induced activity in the lumbosacral spinal cord, underscoring our capability to precisely target specific regions responsible for regulating LUT function.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The FUTURE Study in Refractory OAB: A Step Forward or a Step Back?","authors":"Tufan Tarcan, Enrico Finazzi-Agro, Maurizio Serati","doi":"10.1002/nau.70072","DOIUrl":"https://doi.org/10.1002/nau.70072","url":null,"abstract":"","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Validation and Scale Derivation of the ICIQ-Underactive Bladder Patient Reported Outcome Measure.","authors":"Alan Uren, Nikki Cotterill, Elizabeth D Bacci, Karin Coyne, Zalmai Hakimi, Scott Doyle, Christopher Atzinger, J W Olivier van Till, Paul Abrams","doi":"10.1002/nau.70065","DOIUrl":"https://doi.org/10.1002/nau.70065","url":null,"abstract":"<p><strong>Aims: </strong>To complete the psychometric validation and scale derivation of the International Consultation on Incontinence Questionnaire-Underactive Bladder (ICIQ-UAB).</p><p><strong>Methods: </strong>The developmental ICIQ-UAB was administered within a Phase II randomised controlled trial of a drug for the treatment of underactive bladder at baseline and follow-up 4 weeks after the start of trial medication treatment. Descriptive analyses and exploratory factor analyses (EFAs) informed the derivation of scored domains for symptoms, health-related quality of life (HRQoL), and associated bother items. The reliability was assessed by Cronbach's α, while validity was assessed via the correlation with other concurrently administered PROMs at baseline. Responsiveness was evaluated using the change in mean scores from baseline to follow-up.</p><p><strong>Results: </strong>A total of 132 male and female patients with the symptomatic and urodynamic characteristics of detrusor underactivity were enrolled in the analysis. Descriptive analyses and EFAs informed scored domains for 11 symptom items with associated bother, and 7 HRQoL items with associated bother. A further 8 unscored symptom items and one overall HRQL item were retained for their clinical utility. Sensitivity of the ICIQ-UAB to the severity of the condition was supported (known groups validity), and correlations with concurrent PROMs were as expected, showing evidence of construct validity. All domains demonstrated reliability (Cronbach's α ≥ 0.88). Limited evidence for responsiveness was found, which was likely due to insufficient efficacy of trial medication treatment over administration time-points.</p><p><strong>Conclusions: </strong>The two scored domains and associated bother for the ICIQ-UAB have been shown to be reliable, valid and sensitive to the severity of the condition. The instrument can be recommended to researchers and clinicians for the comprehensive assessment of symptoms and their impact on HRQoL on patients with suspected UAB.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bladder Diary Feasibility and Reliability in Neurogenic Lower Urinary Tract Dysfunction Patients.","authors":"Adrien Haegel, Matthieu Grasland, Hélène Robert, Bertrand Pichon","doi":"10.1002/nau.70063","DOIUrl":"https://doi.org/10.1002/nau.70063","url":null,"abstract":"<p><strong>Objectives: </strong>Bladder diary (BD) is an important tool to understand patients' lower urinary tract symptoms. But few data exist on adult neurogenic lower urinary tract dysfunction (ANLUTD) patients. The aim was to assess in real-life practice the feasibility, reliability and influencing factors of BD completion in patients with ANLUTD.</p><p><strong>Materials and methods: </strong>All patients with ANLUTD who had a first neuro-urologic consultation between January 2022 and April 2023 were included. No patients underwent intermittent self-catheterization. We collected demographic data, validated questionnaires about symptoms and quality of life, the presence and analysis of the 3-day BD. BD was classified as feasible if patients returned it nonempty and was deemed reliable if patients had completed at least 2 consecutive days, if it did not have an intake-output imbalance, and if it were consistent with the USP questionnaire. We investigated influencing factors of feasibility and reliability with a general linear regression.</p><p><strong>Results: </strong>One hundred and nighty-nine patients were included (mean age 56 ± 14; 111 (55.7%) women). Eighty-four (42.2%) had demyelinating disease, 55 (27.6%) Parkinson's disease, 51 (25.6%) neuro-genetic disorder and 7 (4.5%) spinal cord injury or cauda equina syndrome. BD were classified as feasible for 128 (64%) patients and 45 (40.5%) were deemed reliable. In a generalized linear model, no factor was associated with BD feasibility or reliability.</p><p><strong>Conclusions: </strong>In a ANLUTD population, the BD is a feasible tool, but its interpretation should be met with caution due to its limited reliability. No factor was associated with the feasibility or reliability of the BD.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN II) Urinary Urgency Phenotyping Study: Methods and Baseline Urinary Symptoms by Age and Sex.","authors":"Giulia M Ippolito, Kimberly Kenton, Catherine S Bradley, Ting Lu, Brian Bieber, J Quentin Clemens, Anna C Kirby, Ziya Kirkali, Magaly Guerrero, Claire C Yang, Karl Kreder, C Emi Bretschneider, John Graff, Julia Nashif, James W Griffith, H Henry Lai, Cindy L Amundsen, Anne P Cameron","doi":"10.1002/nau.70044","DOIUrl":"https://doi.org/10.1002/nau.70044","url":null,"abstract":"<p><strong>Aims: </strong>To present the methods and baseline findings from a prospective, longitudinal cohort study of treatment seeking adults with urinary urgency (URG) with or without urgency urinary incontinence (UUI).</p><p><strong>Methods: </strong>Adults seeking treatment for URG and/or UUI and controls were enrolled. Participants completed physical examination, urine and serum studies, post-void residual, and validated questionnaires.</p><p><strong>Results: </strong>Data from 809 participants were analyzed. Cases and controls were both predominantly white. The mean overall age of the cases was older (62 vs. 59 years) as was the mean BMI and functional comorbidity index scores. Higher proportions of controls were never smokers. Among cases, bivariate analysis found higher proportions of women reporting URG, URG with fear of leaking, any UI and UUI. Men had higher proportions of often or almost always reporting nocturia. Higher proportions of men reported URG alone and UUI without stress UI. Mixed UI was prevalent among women but rare among men. In logistic regression models, women had higher odds of SUI, UUI, and dysuria compared to men. Men had higher odds of nocturia, intermittency, splitting/spraying, and hesitancy. Older participants had higher odds of UUI, nocturia, any UI, and URG with fear of leakage whereas younger participants had higher odds of stress UI, irritative symptoms.</p><p><strong>Conclusion: </strong>Treatment-seeking adults with URG and/or UUI were older, had higher BMI, worse functional comorbidity index and higher proportions of prior smoking history compared to controls. Among cases, sex and age differences were seen in within the spectrum of URG and UUI.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Artificial Urinary Sphincter Placement on Quality of Life: A Validated Outcome Assessment.","authors":"Austin Martin, Brian J Linder, Jamie J O'Byrne, Daniel S Elliott","doi":"10.1002/nau.70056","DOIUrl":"https://doi.org/10.1002/nau.70056","url":null,"abstract":"<p><strong>Introduction: </strong>Artificial Urinary Sphincter (AUS) placement is the preferred treatment for moderate to severe incontinence following prostate cancer treatment. While device related outcomes related to device survival are well reported, literature on quality-of-life outcomes, including the use of validated measures is limited.</p><p><strong>Methods: </strong>We queried a prospectively maintained database of male patients undergoing primary AUS implantation from 2015 to 2023 at our institution. All patients completed a preoperative Michigan Incontinence Symptom Index (M-ISI) and Patient Global Impression of Improvement (PGI-I). Postoperative quality of life data was obtained by mailed correspondence. Surveys obtained following AUS reoperation/revision were excluded. Pairwise comparisons were performed between preoperative functional status and the Postoperative responses. Logistic regression analysis was performed to identify preoperative variables associated with a favorable PGI-I score defined as \"very much better or much better,\" or a decrease in pad usage from > 1 pad per day to ≤ 1 pad per day.</p><p><strong>Results: </strong>During the study timeframe, 383 patients underwent primary AUS placement, of which 163 patients (42%) completed a postoperative survey and were included in the study. Median age was 69.0 (IQR: 64-74) and 54.6% of patients had a history of pelvic radiation. The median time from surgery to the postoperative survey was 2.2 years (IQR: 0.9, 4.3). Compared to baseline, following AUS placement there was a significant improvement in the total M-ISI score (10 [6, 16) vs 26 [22, 30]; p < 0.0001) (Minimally Important Difference = 4). This included improvements in the SUI subscore [4 (IQR 2, 6) vs 10 (IQR: 9, 12); p < 0.0001] and bother score [1 (IQR: 0, 3) vs 6 (IQR: 5, 7); p < 0.001)]. Pad usage significantly decreased following device placement (p < 0.0001). The vast majority of patients (90.7%) would \"definitely or probably recommend to a friend/family member.\" On univariable analysis, active smoking (ref. never) was associated with adverse pad use outcomes (OR: 0.1, 95% CI: 0-0.8; p = 0.03) and older age was associated with adverse PGI-I outcome (OR: 0.93, 95% CI: 0.87-0.99; p = 0.02).</p><p><strong>Conclusions: </strong>Following AUS implantation, most patients have significant improvement in validated quality of life outcomes and low pad usage. These findings persist despite multiple preoperative comorbidities and should be considered when counseling patients before AUS placement.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to the Editor: Conformity of ChatGPT Recommendations With the AUA/SUFU Guideline on Postprostatectomy Urinary Incontinence.","authors":"Vicktor Bruno Pereira Pinto, Jose de Bessa, Cristiano Mendes Gomes","doi":"10.1002/nau.70033","DOIUrl":"https://doi.org/10.1002/nau.70033","url":null,"abstract":"","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Magnetic Stimulation in Men With Urinary Incontinence After Radical Prostatectomy: A Randomized, Quadruple-Blind, Sham-Controlled Clinical Trial.","authors":"Burak Unal, Ayşe Sarsan, Necmettin Yıldız, Hakan Alkan","doi":"10.1002/nau.70055","DOIUrl":"https://doi.org/10.1002/nau.70055","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy of MStim on incontinence-related clinical parameters, quality of life (QoL), sexual function, depression and anxiety in patients with UI after RP.</p><p><strong>Methods: </strong>Forty men with UI after RP were randomized into two groups using the random numbers generator as follows: Group 1 received MStim (n: 20), and Group 2 Sham-MStim (control) (n: 20). MStim and Sham-Mstim were performed with MStim therapy armchair (Novamag NT60), 2 days a week, 20 min a day, a total of 16 sessions for 8 weeks. Men were evaluated in terms of improvement rates (primary outcome), severity of incontinence (24 h-pad test), frequency of voiding, nocturia, incontinence episodes, number of pads, (3-day bladder diary) anxiety-depression (HADS), QoL (IIQ-7), sexual function (IIEF), and continence rates and treatment satisfaction.</p><p><strong>Results: </strong>While there was a statistically significant improvement in all parameters except erectile function, sexual desire, and intercourse satisfaction and overall satisfaction subgroups of sexual function and depression Group 1, a statistically significant improvement was found only in the severity of incontinence and bladder diary parameters in Group 2 at the 8th week compared to the baseline values (p < 0.05). At the end of treatment; the severity of incontinence, nocturia, incontinence episodes, QoL, total and orgasmic function subgroups of sexual function and anxiety were significantly improved in Group 1 compared to Group 2 at the 8th week (p < 0.05). The improvement rates (75.0% vs. 26.3%), continence rates (45.0% vs. 15.8%), and treatment satisfaction (effect size: d = 1.23) were significantly higher in Group 1 than in Group 2 (p < 0.05).</p><p><strong>Conclusion: </strong>MStim is a clinically feasible treatment option that is well tolerated with no serious side effects and is more effective than sham on both UI related clinical parameters and QoL, anxiety and sexual function in men with UI after RP.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov number, NCT04644614.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}