Neurourology and Urodynamics最新文献

{"title":"Analysis of Nocturia Determinants Using a Novel Portable Urine-Measuring Device.","authors":"Kotaro Yamasue, Tomohiko Kaneoka, Tomoyuki Tatenuma, Masanari Umemura","doi":"10.1002/nau.25667","DOIUrl":"https://doi.org/10.1002/nau.25667","url":null,"abstract":"<p><strong>Aims: </strong>To investigate the relationship between nocturia and values measured using a novel multifunctional portable urine-measuring device.</p><p><strong>Methods: </strong>Thirty-five older men with nocturia and/or high-normal or high blood pressure were enrolled to record measurements on one full day (24 h) and two nights using the portable device during urination. Participants used a semi-conical cup with a small hole equipped with a conductivity sensor, temperature sensor, and timer to measure urine volume, salt content, urine temperature, and urination speed.</p><p><strong>Results: </strong>Two participants were excluded owing to oliguria. The mean age of 33 participants was 75.2 ± 7.4 years (range: 55-85 years). The mean nocturnal urination frequency, including the first urination after waking, was 2.1 ± 0.6 times. Simple correlation analysis revealed that nocturnal urine frequency significantly increased with nocturnal urine volume (r = 0.65, p < 0.001) and salt content (r = 0.57, p < 0.001) but not with 24-h urine volume and salt content. Furthermore, the frequency significantly decreased with nocturnal urine temperature (r = -0.37, p < 0.05). No significant relationship was observed between morning blood pressure and nocturnal urination frequency. A high correlation was observed between nighttime urine volume and salt content (r = 0.73, p < 0.001).</p><p><strong>Conclusions: </strong>Nocturnal urine volume, salt content, and urine temperature are significantly correlated with nocturia. The portable urine-measuring device could guide nocturia reduction through facilitation of the reduction of nocturnal urine volume and salt content, in addition to urine temperature monitoring.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Intrathecal Baclofen on Bladder Function in Patients With Severe Supraspinal Spasticity.","authors":"Markus Kofler, Lucas-Michael Halbmayer, Gusztav Kiss, Heinrich Matzak, Giangaetano D'Aleo, Leopold Saltuari, Helmut Madersbacher, Elke Pucks-Faes","doi":"10.1002/nau.25666","DOIUrl":"https://doi.org/10.1002/nau.25666","url":null,"abstract":"<p><strong>Introduction: </strong>Neurogenic bladder dysfunction is a prevalent condition characterized by impaired bladder control resulting from neurological conditions, for example, spinal cord injury or traumatic brain injury (TBI). Detrusor overactivity is a typical symptom of central nervous system damage. A lesion affecting the pontine neural network typically results in loss of tonic inhibition exerted by the pontine micturition center and causes involuntary detrusor contractions. Intrathecal baclofen (ITB), primarily indicated for spasticity management, holds potential in addressing the underlying mechanisms of neurogenic bladder dysfunction.</p><p><strong>Methods: </strong>Urodynamic data were extracted from clinical charts of patients with severe supraspinal spasticity who received ITB treatment. Urodynamic studies were performed before pump implantation (PRE), after surgery (POST), and when achieving an effective steady state ITB dosage (ss-ITB), as reflected by a reduction in Modified Ashworth Scale (MAS) score. To determine potential risk factors for a poor response to ITB with respect to bladder function, patients were post hoc categorized into good and poor responders based on post void residual volume at ss-ITB.</p><p><strong>Results: </strong>Apart from significantly reducing MAS scores, ITB caused significant increases in reflex volume, bladder capacity, and residual volume, and significant decreases in maximal detrusor and vesical pressures. Significant differences between good and poor responders (with respect to bladder function) were noted for reflex volume, bladder capacity, and residual volume at ss-ITB, whereas no urodynamic parameter served to differentiate the two groups at PRE.</p><p><strong>Discussion: </strong>This study confirms a beneficial effect of ITB on bladder function in patients with severe supraspinal spasticity. However, concurring with the literature, a small subgroup of patients experienced serious deterioration in terms of increased reflex volume and residual volume, posing the risk of subsequent renal damage. Unfortunately, no urodynamic parameter predicted such a poor response to ITB before treatment initiation.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inspiration From Simplified Ligament Repair in Stress Urinary Incontinence.","authors":"Aybüke Tayarer, Filiz Dişçi","doi":"10.1002/nau.25668","DOIUrl":"https://doi.org/10.1002/nau.25668","url":null,"abstract":"","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Should We Be Treating Affective Symptoms, Like Anxiety and Depression Which May Be Related to LUTD in Patients With OAB? ICI-RS 2024.","authors":"Mauro Van den Ende, Apostolos Apostolidis, Sanjay Sinha, George Bou Kheir, Rayan Mohamed-Ahmed, Caroline Selai, Paul Abrams, Desiree Vrijens","doi":"10.1002/nau.25662","DOIUrl":"https://doi.org/10.1002/nau.25662","url":null,"abstract":"<p><strong>Aims: </strong>To discuss the role of screening and treatment of affective symptoms, like anxiety and depression in patients with LUTD. A review of the literature regarding the bidirectional association and multidisciplinary approaches integrating psychometric assessments with personalized treatment plans to improve diagnostic accuracy and therapeutic outcomes of LUTD.</p><p><strong>Methods: </strong>This review summarizes discussions and a narrative review of (recent) literature during an International Consultation on Incontinence-Research Society 2024 research proposal with respect to the role of screening for anxiety and depression, effect of mental health symptoms on treatment outcomes and future implications.</p><p><strong>Results: </strong>Consensus recognized the importance to incorporate attention to anxiety and depression in relation to LUTD. The awareness of this association can lead to better outcomes. Future research projects are proposed to evaluate the bidirectional relationship.</p><p><strong>Conclusion: </strong>The relationship between affective symptoms and LUTD underscores the need for integrated treatment approaches that address both psychological and urological dimensions. Further research is required to identify specific patient subgroups that would benefit most from these interventions, to develop standardized screening tools, and to refine treatment protocols. Multidisciplinary care, incorporating psychological assessment and personalized treatment strategies, could enhance outcomes for LUTD patients.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep Learning and Numerical Analysis for Bladder Outflow Obstruction and Detrusor Underactivity Diagnosis in Men: A Novel Urodynamic Evaluation Scheme.","authors":"Haonan Mei, Zhishun Wang, Qingyuan Zheng, Panpan Jiao, Shengqi Lv, Xiuheng Liu, Hui Chen, Rui Yang","doi":"10.1002/nau.25665","DOIUrl":"https://doi.org/10.1002/nau.25665","url":null,"abstract":"<p><strong>Objectives: </strong>To automatically identify and diagnose bladder outflow obstruction (BOO) and detrusor underactivity (DUA) in male patients with lower urinary tract symptoms through urodynamics exam.</p><p><strong>Patients and methods: </strong>We performed a retrospective review of 1949 male patients who underwent a urodynamic study at two institutions. Deep Convolutional Neural Networks scheme combined with a short-time Fourier transform algorithm was trained to perform an accurate diagnosis of BOO and DUA, utilizing five-channel urodynamic data (consisting of uroflowmetry, urine volume, intravesical pressure, abdominal pressure, and detrusor pressure). We used fivefold cross-validation, constructing training and internal test sets from 1725 patients from Renmin Hospital of Wuhan University (RHWU) at a 4:1 ratio, and used an independent external validation set consisting of 224 patients from The Central Hospital of Wuhan (TCHO) to build and evaluate the DI model. We further conducted subgroup analyses to provide a more detailed description of the AI model's interpretability regarding urodynamics.</p><p><strong>Results: </strong>The AUC scores of BOO and DUA, which were measured through the STFT-based deep learning method, were 0.945 ± 0.020 and 0.929 ± 0.039 in RHWU and 0.881 and 0.850 in TCHO, respectively. The diagnostic efficiency of other subgroup analyses and indicators was also effective.</p><p><strong>Conclusion: </strong>In this study, the proposed deep neural network combined with the short-time Fourier transform method is robust and feasible for interpreting the results of urodynamics in men and has the potential for application to assist clinicians in real clinical settings.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased Afferent Nerve Firing Is Correlated With the Detection of Bladder Wall Micromotion in a Perfused Ex-Vivo Porcine Model.","authors":"Ryan W Fogg, Mina P Ghatas, Brendan McCormack, Michael Shields, Ashley N Matthew, Gabrielle Grob, Nat Araia, Linda Burkett, John E Speich, Adam P Klausner","doi":"10.1002/nau.25661","DOIUrl":"https://doi.org/10.1002/nau.25661","url":null,"abstract":"<p><strong>Introduction and objective: </strong>Observable autonomous rhythmic changes in intravesical pressure, termed bladder wall micromotion, is a phenomenon that has been linked to urinary urgency, the key symptom in overactive bladder (OAB). However, the mechanism through which micromotion drives urinary urgency is poorly understood. In addition, micromotion is inherently difficult to study in human urodynamics due to challenges distinguishing it from normal cyclic physiologic processes such as pulse rate, breathing, rectal contractions, and ureteral jetting. Therefore, the goal of this study was to create a reproducible model of micromotion using an ex-vivo perfused porcine bladder, as well as to describe the relationship between micromotion and afferent nerve signaling.</p><p><strong>Methods: </strong>Porcine bladders were reanimated using ex-vivo perfusion with a physiologic buffer. The pelvic nerve adjacent to the bladder was dissected, grasped with micro-hook electrodes and electroneurogram (ENG) signals were recorded at 20 kHz. Bladders were catheterized and intravesical pressure measurements were taken using a Laborie XT Urodynamics system. Bladders were filled to a fixed volume of 300 mL and control measurements were recorded. The bladders were then washed with 0.001 M carbachol (CCh) solution and refilled to 300 mL to induce micromotion, which was detected as rhythmic changes in intravesical pressure. ENG amplitude was calculated in μV, and nerve firing rate was calculated as number of spikes above baseline threshold per minute.</p><p><strong>Results: </strong>Micromotion was induced by carbachol in 12/25 (48.4%) of trials as rhythmic changes in intravesical pressure after the instillation of carbachol but not in any control period. A fast Fourier transform (FFT) algorithm showed average peak dominant frequency component amplitude was significantly higher during the carbachol period when compared to the control period (0.47 vs. 0.01 cm-H₂O, p < 0.0001). Peak waveform frequency (1.13 vs. 1.54 cycles/min, p > 0.05) did not differ between control and carbachol periods. With regard to afferent nerve signaling, normalized average amplitude (0.66 ± 0.24 vs. 0.05 ± 0.08 μV) and firing rate (0.68 ± 0.28 vs. 0.18 ± 0.22 spike/min) for all bladders was significantly greater in the carbachol period when compared to the control period (p < 0.001).</p><p><strong>Conclusions: </strong>Micromotion can be induced using instillation of carbachol in a perfused ex-vivo porcine bladder. Increased afferent nerve firing is observed during periods of micromotion. Thus, micromotion may drive afferent nerve signaling and may potentially contribute to urinary urgency, detrusor overactivity, and OAB. The development of an experimental ex-vivo porcine model for micromotion provides a reproducible method to study bladder micromotion and its potential role in the pathophysiology of urinary urgency and voiding dysfunction.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do We Have Sufficient Evidence to Derive Innovative Approaches to Assessing Unmet Need, Delivering Education on Bladder and Bowel Continence Health, and Providing a Better Environment for Joint Decision-Making? ICI-RS 2024.","authors":"Nikki Cotterill, Michael Samarinas, Angie Rantell, Caroline Selai, Salvador Arlandis, Kathryn Jones, Paul Abrams, D Robinson, Adrian Wagg","doi":"10.1002/nau.25654","DOIUrl":"https://doi.org/10.1002/nau.25654","url":null,"abstract":"<p><strong>Context: </strong>Improved continence outcomes are reliant on identification of unmet need, education delivery, and shared decision-making. The evidence base on which to derive innovative approaches in these areas was unclear.</p><p><strong>Methods: </strong>A debate held at the International Consultation on Incontinence-Research Society meeting, held in Bristol in June 2024, considered ways to improve research requirements to advance these areas.</p><p><strong>Results and conclusion: </strong>Artificial intelligence solutions and digital approaches to healthcare are emerging at pace and offer possibilities to improve these three key areas but this must be driven by person-centered approaches. Care must be taken to avoid increasing inequality through digital exclusion and language barriers. Research questions are highlighted to derive innovation in these three key areas.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRI-Derived Transition Zone Index Is Highly Predictive of Urodynamic Bladder Outlet Obstruction Prior to Holmium Laser Enucleation of the Prostate.","authors":"Madison T Taychert, Shane A Wells, Jordan R Krieger, Ethan Richmond, Glenn O Allen, Emily Serrell, Ali S Antar, Margaret A Knoedler, Christopher M Manakas, Dan R Gralnek, Matthew D Grimes","doi":"10.1002/nau.25660","DOIUrl":"https://doi.org/10.1002/nau.25660","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction and objective: &lt;/strong&gt;Urodynamic study (UDS) is required to diagnose bladder outlet obstruction (BOO) during evaluation of benign prostatic hyperplasia (BPH) but is seldom performed due to cost and invasiveness. Therefore, anatomic and clinical parameters to predict BOO have been proposed, including the prostate transition zone index (TZI) which is the ratio of prostate transition zone volume (TZV) to whole gland volume (WGV). Historically computed with ellipsoid volume estimation of prostate WGV and TZV from transrectal ultrasound measurements, controversy exists regarding the utility of TZI to predict likelihood of BOO on UDS and clinical outcomes following BPH surgery. Here, we aim to assess the association between MRI-measured TZI and BOO on preoperative UDS in a modern BPH cohort before holmium laser enucleation of the prostate (HoLEP).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A prospectively maintained institutional database of 944 consecutive HoLEP patients between 2018 and 2022 was reviewed to identify those with preoperative UDS and MRI within 1 year of surgery. UDS was used to measure bladder outlet obstruction index (BOOI). 3D WGV and TZV were estimated using clinically available software (DynaCAD). We used linear regression to assess the relationship between TZI, WGV, and BOOI and logistic regression to determine the association between TZI, WGV, and BOO (defined as BOOI &gt; 40).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;45/944 (4.8%) patients had both preoperative UDS and MRI within 1 year of HoLEP. Of these, 27 patients were obstructed (BOOI &gt; 40) and 18 patients were not obstructed (BOOI ≤ 40) on preoperative UDS. Obstructed patients had larger prostate WGV, TZV, and TZI compared to non-obstructed patients but were otherwise similar with respect to preoperative characteristics. Univariate analysis showed a positive association between TZI and BOO (R&lt;sup&gt;2&lt;/sup&gt; = 0.373, p &lt; 0.001) and WGV and BOO (R&lt;sup&gt;2&lt;/sup&gt; = 0.214, p &lt; 0.001). Multivariable logistic regression showed that TZI was independently associated with BOO (OR 1.08, 95% CI 1.02-1.14, p = 0.013) while accounting for WGV. WGV was not independently associated with BOO while accounting for TZI (OR 1.00, 95% CI 0.98-1.01, p = 0.614). The Youden index was utilized to create an optimal cutpoint for TZI (0.528) above which urodynamic BOO was very likely on multivariate logistic regression while accounting for WGV (OR 25.0, 95% CI 3.40-183.58, p = 0.002). The generated cutpoint for WGV (61.5 mL) was not significantly associated with urodynamic BOO on multivariate logistic regression while accounting for TZI (OR 0.993, 95% CI 0.98-1.01, p = 0.452).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Noninvasive MRI measurement of prostate TZI was highly and independently predictive of BOO before HoLEP and superior to WGV alone. This suggests that MRI obtained in evaluation of BPH/LUTS patients may be used to calculate TZI and inform patient selection for invasive urodynamic study and surgic","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Should the BCI and BOOI Index be Correctly Applied in Patients With Low-Compliance Bladder?","authors":"Xiao Zeng, Ting Kang, WenJiao Huang, Tao Jin","doi":"10.1002/nau.25663","DOIUrl":"https://doi.org/10.1002/nau.25663","url":null,"abstract":"","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142952357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Posterior Tibial Nerve Stimulation on Early Continence Following Extraperitoneal Laparoscopic Radical Prostatectomy With Three Trocars.","authors":"Yigit Akin, Enis Mert Yorulmaz, Osman Kose, Serkan Ozcan, Sacit Nuri Gorgel, Erbay Tumer","doi":"10.1002/nau.25659","DOIUrl":"https://doi.org/10.1002/nau.25659","url":null,"abstract":"<p><strong>Aim: </strong>Posterior tibial nerve stimulation (PTNS) might stimulate the sacral nerves and lead to work pelvic floor muscles. We evaluated to effects of PTNS on continence results after extraperitoneal laparoscopic radical prostatectomy (eLRP) with three trocars during early post operative period.</p><p><strong>Methods: </strong>Prospectively recorded data of eLRP with three trocars was retrospectively reviewed for continence results between January 2017 and April 2024. Demographic, clinical, and follow-up data including age, prostate-specific antigen, prostate volume, nerve sparing surgery, and Gleason score were considered for match-paired analysis criteria. Patients were divided into two groups according to whether received PTNS therapy after surgery or not. Group 1 consisted of patients without PTNS (n = 66), and Group 2 consisted of patients who were applied PTNS (n = 66) after eLRP. Continence status, urine loss ratio (ULR), ICIQ-SF, and SF-12 Quality of Life Scale were recorded during outpatient control after 2nd, 3rd, 6th and 12th months of surgery. Statistically significant p was p ≤ 0.05.</p><p><strong>Results: </strong>Mean follow-up was 25 ± 8.7 months. There were 66 patients in each group and match-paired analyses were performed. Group 2 had significant lower incontinence rate and ICIQ-SF score at second and third months follow-up (p = 0.026 and p = 0.045; p = 0.044 and p = 0.031 respectively). Group 2 had significantly higher Physical Component Summary (PCS) and Mental Component Summary (MCS) (p = 0.005 and p = 0.011 for PCS; p = 0.008 and p = 0.025 for MCS, respectively) at second and third months follow-up. Additionally, ULR was significant better in Group 2 at second and third month of surgery (p = 0.042, p = 0.037, respectively). All these parameters were comparable between groups after sixth and 12th months.</p><p><strong>Conclusions: </strong>PTNS can be safely applied to provide early continence in patients underwent eLRP. Due to improved functional outcomes, higher quality of life might be gained in early follow-up period.</p>","PeriodicalId":19200,"journal":{"name":"Neurourology and Urodynamics","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}