Neurophysiologie Clinique/Clinical Neurophysiology最新文献

{"title":"How can emotion and familiarity improve own-name oddball paradigms?","authors":"Estelle Pruvost-Robieux ,&nbsp;Sarah Benghanem ,&nbsp;Camille Des Lauriers ,&nbsp;Anaïs Llorens ,&nbsp;Martine Gavaret","doi":"10.1016/j.neucli.2025.103050","DOIUrl":"10.1016/j.neucli.2025.103050","url":null,"abstract":"<div><div>The own-name paradigm is used to assess the depth of consciousness disorders in patients in intensive care units. This auditory oddball paradigm elicits a positive event-related potential at 300 ms (named P300) after the presentation of a deviant auditory stimulus, here the subject's own-name. This P300 likely reflects the neural processing of the novel stimulus, which can trigger a behavioral response. Presence of a P300 response is considered to be indicative of a good prognosis for recovering to wakefulness in post-anoxic coma patients. However, its prognostic performance is insufficient and some disorders of consciousness patients without a P300 response will nevertheless awake. The auditory P300 response is influenced by the acoustic characteristics of the stimuli. The use of stimuli with an emotional valence may recruit additional brain networks besides the auditory and attentional ones and potentially improve the prognostic value of the P300 response. Moreover, better characterization of the recruitment of different brain networks involved in these P300 responses in response to emotional stimuli would help in understanding the surface event-related potentials. Here, we present two kind of emotional acoustic features that can be used in these paradigms: “smiling” versus “rough” voice and the familiarity of the voice.</div></div>","PeriodicalId":19134,"journal":{"name":"Neurophysiologie Clinique/Clinical Neurophysiology","volume":"55 3","pages":"Article 103050"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative recordings from the posterior superior insula in awake humans with peripheral neuropathic pain","authors":"Raíssa Benocci Thibes ,&nbsp;Pedro Henrique Martins da Cunha ,&nbsp;Jorge Dornellys da Silva Lapa ,&nbsp;Liu Dongyang ,&nbsp;Denise Spinola Pinheiro ,&nbsp;Ricardo Ferrareto Iglesio ,&nbsp;Kleber Paiva Duarte ,&nbsp;Valquiria Aparecida Silva ,&nbsp;Gabriel Taricani Kubota ,&nbsp;Manoel Jacobsen Teixeira ,&nbsp;Luis Garcia-Larrea ,&nbsp;Hélène Bastiji ,&nbsp;João Ricardo Sato ,&nbsp;Daniel Ciampi de Andrade","doi":"10.1016/j.neucli.2025.103056","DOIUrl":"10.1016/j.neucli.2025.103056","url":null,"abstract":"<div><h3>Background and Objectives</h3><div>The activity profile of the posterior insula in neuropathic pain (NeP) remains largely unexplored. To address this and examine its modulation by somatosensory stimulation, we recorded local field potentials (LFP) in awake patients with NeP undergoing deep brain stimulation (DBS) electrode implantation to the posterior-superior insula (PSI) for analgesic purposes.</div></div><div><h3>Materials and Methods</h3><div>Six patients (one woman; 32–45 years), experiencing refractory peripheral NeP and having previously responded to non-invasive stimulation of the PSI underwent stereotactic implantation of DBS electrodes to the PSI as part of a phase II clinical trial. The averaged power of frequencies of LFP and their peaks were calculated during rest and under thermal painful and mechanical non-painful stimulation.</div></div><div><h3>Results</h3><div>At rest, amplitude peaks within the delta (average min-max.: 2.2 Hz; 1.3–3.7) and theta (6.1 Hz, varying between 5.7 and 6.8 Hz) bands were identified. Compared to rest, both tonic thermal painful, and mechanical non-painful stimulation led to similar mean decreases in gamma power (-24.46 ± 70.56, and -19.56 ± 3.08; respectively). Painful stimuli caused an increase in all the other frequency bands, mainly in alpha and beta ranges, while non-painful stimulation led to decreases in power in all frequencies above 4Hz. Painful tonic stimulation was associated with a significantly greater power variability, both in amplitude and frequency, compared to nonpainful mechanical stimulation.</div></div><div><h3>Conclusion</h3><div>The posterior insula resting state activity in awake patients with chronic NeP was characterized by predominant theta oscillations. Painful and innocuous stimulation led to opposite spectral changes, with a much larger variability across the whole frequency spectrum for painful stimuli, relative to both resting state and non-painful stimulation.</div></div>","PeriodicalId":19134,"journal":{"name":"Neurophysiologie Clinique/Clinical Neurophysiology","volume":"55 3","pages":"Article 103056"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SEEG around the world","authors":"Aileen McGonigal ,&nbsp;Philippe Kahane ,&nbsp;Louis Maillard ,&nbsp;Giorgio Lo Russo ,&nbsp;Patrick Chauvel","doi":"10.1016/j.neucli.2025.103074","DOIUrl":"10.1016/j.neucli.2025.103074","url":null,"abstract":"","PeriodicalId":19134,"journal":{"name":"Neurophysiologie Clinique/Clinical Neurophysiology","volume":"55 3","pages":"Article 103074"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Description of an alternative method for the electrodiagnostic evaluation of the sensory radial nerve","authors":"Martin Moussy ,&nbsp;Julie Rode ,&nbsp;Thierry Maisonobe ,&nbsp;Nagham Khanafer ,&nbsp;Françoise Bouhour ,&nbsp;Antoine Pegat","doi":"10.1016/j.neucli.2025.103058","DOIUrl":"10.1016/j.neucli.2025.103058","url":null,"abstract":"<div><h3>Objectives</h3><div>The aim of this study was to describe an alternative method for the electrodiagnostic (EDX) evaluation of the sensory radial nerve (SRN).</div></div><div><h3>Methods</h3><div>In this retrospective study, all patients from a French EDX center (November 2022-April 2023) for whom SNAP amplitudes of the same SRN were obtained through both a conventional and an alternative method were included. In the conventional method, the active recording electrode was placed at the base of the snuff box, whereas in the alternative method, it was placed 3<del>-4</del> cm proximally on the lateral border of the radial bone. The SNAP amplitudes of both methods were compared and the ratio of alternative to conventional amplitude was determined within the same patient. A secondary objective was to compare SNAP amplitudes and ratios between patients with peripheral neuropathy and those without (control group).</div></div><div><h3>Results</h3><div>Among the 117 patients included, the mean ± SD SNAP amplitude was 50.0±28.9 µV in the alternative method compared to 31.0±17.9 µV in the conventional method. The ratio of alternative to conventional amplitudes was 1.64±0.4 in all patients. No significant difference in amplitude ratios was found between the peripheral neuropathy group (1.63 ± 0.4) and the control group (1.65 ± 0.3; p =0.75).</div></div><div><h3>Discussion</h3><div>The alternative method, based on a more proximal placement of the recording electrodes, consistently provided larger SNAP amplitudes than the conventional method. This method could be useful in particular clinical settings but could prove more challenging in obese or muscular patients.</div></div>","PeriodicalId":19134,"journal":{"name":"Neurophysiologie Clinique/Clinical Neurophysiology","volume":"55 3","pages":"Article 103058"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143327918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combining quantified EEG with clinical measures to better predict outcomes of acute disorders of consciousness","authors":"Huimin Zhang ,&nbsp;Shuting Chai ,&nbsp;Dawei Shan,&nbsp;Gang Liu,&nbsp;Yan Zhang","doi":"10.1016/j.neucli.2025.103048","DOIUrl":"10.1016/j.neucli.2025.103048","url":null,"abstract":"<div><h3>Objective</h3><div>To explore the application of the neuronal recovery model (i.e., the ABCD model derived from EEG power spectral analysis) in forecasting outcomes for patients with acute disorders of consciousness (DOC).</div></div><div><h3>Methods</h3><div>Patients with acute DOC were enrolled, and clinical assessments, including the Glasgow Coma Scale (GCS), Full Outline of UnResponsiveness (FOUR), and Coma Recovery Scale-Revised (CRS-R) scores, along with electroencephalography (EEG), were documented on the first day post-enrollment. The ABCD model, derived from EEG power spectral data reflecting frequency bands, categorized brain activity into four distinct groups (A, B, C, D). Outcome prognoses were evaluated using the Glasgow Outcome Scale-Extended (GOSE) six months after enrollment. Statistical analyses were performed to assess the correlation between the ABCD model and clinical assessments, and to investigate the predictive value of EEG and clinical assessments for the long-term prognosis.</div></div><div><h3>Results</h3><div>A total of 93 patients with acute DOC were included; the median age was 64 years (interquartile range 52, 72), of which 52 patients had favorable outcomes. Significant correlations were observed between the ABCD model and both the FOUR and CRS-R scores. The CRS-R and ABCD model demonstrated relatively good predictive value for six-month prognoses, with Area Under the Curve (AUC) values of 0.695 and 0.678, respectively (<em>P</em> &lt; 0.05). Furthermore, the combination of the CRS-R score and ABCD model exhibited the highest predictive value with an AUC of 0.746.</div></div><div><h3>Conclusions</h3><div>The ABCD model effectively predicted the prognosis of patients with acute DOC in combination with CRS-R.</div></div>","PeriodicalId":19134,"journal":{"name":"Neurophysiologie Clinique/Clinical Neurophysiology","volume":"55 2","pages":"Article 103048"},"PeriodicalIF":2.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143008869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of neurophysiological monitoring in differentiation of hemifacial spasm and post-facial paralysis synkinesis","authors":"Tingting Ying ,&nbsp;Wenxiang Zhong ,&nbsp;Yan Yuan,&nbsp;Li Zhou,&nbsp;Shiting Li","doi":"10.1016/j.neucli.2024.103019","DOIUrl":"10.1016/j.neucli.2024.103019","url":null,"abstract":"<div><h3>Objective</h3><div>The aims of this study were to investigate the electrophysiological features of hemifacial spasm (HFS) and post-facial paralysis synkinesis (PFPS) that contribute to differential diagnosis.</div></div><div><h3>Methods</h3><div>This study was designed as a retrospective analysis, focusing on 132 patients diagnosed with HFS and 78 patients with PFPS between May and October 2023. Patient data were collected from existing medical records. The study aimed to analyze pre-existing electrophysiological data, including abnormal muscle response (AMR) and facial synkinesis, focusing on parameters such as AMR latency, amplitude, and duration.</div></div><div><h3>Results</h3><div>In the HFS group, AMR could be induced in all patients, with synkinesis present in 31.8 %. In the PFPS group, AMR and synkinesis were induced in 79.5 % and 100 % of patients, respectively. Compared with the PFPS group, the HFS group had a shorter AMR latency and higher amplitude (<em>P</em> &lt; 0.05). The duration of the AMR did not significantly differ between the two groups (<em>P</em> &gt; 0.05). Synkinesis in the HFS group was typically accompanied or followed by an involuntary spasm episode, but not every eye closure or pouting led to synkinesis. In contrast, synkinesis in the PFPS group occurred with every voluntary movement and was synchronized with these movements.</div></div><div><h3>Conclusions</h3><div>Patients with HFS and PFPS may exhibit similar clinical symptoms. Neurophysiological tests, particularly electromyography, provide valuable information for the differential diagnosis of HFS and PFPS.</div></div>","PeriodicalId":19134,"journal":{"name":"Neurophysiologie Clinique/Clinical Neurophysiology","volume":"55 2","pages":"Article 103019"},"PeriodicalIF":2.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurophysiology of adaptative and maladaptive stress: Relations with psychology of stress","authors":"Marion Trousselard","doi":"10.1016/j.neucli.2024.103036","DOIUrl":"10.1016/j.neucli.2024.103036","url":null,"abstract":"<div><h3>Objectives</h3><div>The stress reaction is an integrated response to a change in the environment that enables each individual to adapt to demand. While this response is physiologically coordinated by the brain, its phenomenology is expressed in the field of psychology and psychopathology. This interrelation between neurophysiological mechanisms and psychological processes is complex as dynamic interpersonal, biological, and psychocognitive systems interact with contextual and environmental factors to shape adaptation over the life constraints.</div></div><div><h3>Method</h3><div>This article aims to present the actors of the adjusted stress response, such as coping and coping flexibility, mindfulness and resilience, and their respective neurophysiology.</div></div><div><h3>Results</h3><div>A model of the relationship between resilience, mindfulness and coping was proposed for optimizing adaptation to stress response.</div></div><div><h3>Discussion</h3><div>These focuses are prerequisites for understanding and supporting human adaptation in the everyday environment and promoting efficient management of stress for mental and physical health.</div></div>","PeriodicalId":19134,"journal":{"name":"Neurophysiologie Clinique/Clinical Neurophysiology","volume":"55 2","pages":"Article 103036"},"PeriodicalIF":2.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the efficacy of transcranial direct current stimulation (tDCS) in managing neuropathic pain-induced emotional consequences: Insights from animal models","authors":"Bahrie Ramadan,&nbsp;Vincent Van Waes","doi":"10.1016/j.neucli.2025.103055","DOIUrl":"10.1016/j.neucli.2025.103055","url":null,"abstract":"<div><div>Neuropathic pain is a global health concern due to its severity and its detrimental impact on patients’ quality of life. It is primarily characterized by sensory alterations, most commonly hyperalgesia and allodynia. As the disease progresses, patients with neuropathic pain develop co-occurring emotional disorders, such as anxiety and depression, which further complicate therapeutic management. While pharmacotherapy remains the first-line treatment, limitations in its efficacy and the prevalence of side effects often leave patients with insufficient pain relief. Transcranial direct current stimulation (tDCS), a non-invasive brain stimulation technique, has recently emerged as a promising alternative for chronic pain management. This review provides an overview of preclinical studies examining the effects of tDCS in rodent models of neuropathic pain. It specifically highlights the potential of tDCS to modulate the emotional-affective component of pain, with a focus on identifying optimal cortical targets for stimulation to enhance the translational application of tDCS in managing pain-related emotional disorders.</div></div>","PeriodicalId":19134,"journal":{"name":"Neurophysiologie Clinique/Clinical Neurophysiology","volume":"55 2","pages":"Article 103055"},"PeriodicalIF":2.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduced montage electroencephalography: A choice between pragmatism and conventionalism","authors":"Josef Parvizi ,&nbsp;Kapil Gururangan","doi":"10.1016/j.neucli.2025.103063","DOIUrl":"10.1016/j.neucli.2025.103063","url":null,"abstract":"","PeriodicalId":19134,"journal":{"name":"Neurophysiologie Clinique/Clinical Neurophysiology","volume":"55 2","pages":"Article 103063"},"PeriodicalIF":2.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cortical Stimulation for brain mapping and seizure stimulation, pediatric practices throughout Canada: A national survey and systematic literature review","authors":"Margarita Maltseva ,&nbsp;Juan Pablo Appendino ,&nbsp;Pavlina Cabounova ,&nbsp;Andrea Andrade ,&nbsp;Michelle Kregel ,&nbsp;Aris Hadjinicolaou ,&nbsp;Alexander G. Weil ,&nbsp;Puneet Jain ,&nbsp;Elizabeth Donner ,&nbsp;Felippe Borlot ,&nbsp;David Dufresne ,&nbsp;Linda Huh ,&nbsp;Natarie Liu ,&nbsp;Kenneth A. Myers ,&nbsp;Julia Jacobs","doi":"10.1016/j.neucli.2025.103043","DOIUrl":"10.1016/j.neucli.2025.103043","url":null,"abstract":"<div><h3>Introduction</h3><div>Diagnostic cortical stimulation (CS) in intracranial electroencephalography (iEEG) is an established epilepsy presurgical assessment tool to delineate relevant brain functions and elicit habitual epileptic seizures. Currently, no consensus exists as to whether CS should be routinely performed in pediatric patients. A significant challenge is their limited ability to cooperate during the procedure or to describe non-observable seizure semiology features. Our goal was to identify the spectrum of CS practices in Canada, for both eloquent cortex mapping and seizure stimulation.</div></div><div><h3>Methods</h3><div>An online survey, answered by all 8 Canadian pediatric epilepsy centers, enquired about implantation, stimulation methods, and use of standardized protocols. A systematic literature review extracted detailed stimulation parameters.</div></div><div><h3>Results</h3><div>Most of the institutions (<em>n</em> = 7/8) reported performing CS during presurgical evaluation. Four institutions indicated they perform stimulation in all implanted patients for the purpose of eloquent cortex mapping and seizure stimulation. The majority of physicians had their individual approach to CS. A largely variable approach to CS, mainly in the choice of stimulation parameters (i.e., train and pulse duration), was observed, with the highest variance concerning the purpose of seizure stimulation. The literature review highlighted an overall small sample size and minimal number of publications. Even though there is a rising trend towards stereotactic iEEG implantation, more data were available on subdural EEGs.</div></div><div><h3>Conclusion</h3><div>This study shows individual and sparsely validated approach to CS in pediatric epilepsy. The literature review underscores the urgent need to harmonize pediatric intracranial EEG practices. More multicenter studies are needed to identify safe stimulation thresholds and allow implementation of evidence-based guidelines.</div></div>","PeriodicalId":19134,"journal":{"name":"Neurophysiologie Clinique/Clinical Neurophysiology","volume":"55 2","pages":"Article 103043"},"PeriodicalIF":2.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143282721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}