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Journal of Diabetes Investigation最新文献

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Comment on "A machine learning approach to predicting severe diabetes distress in adults with type 1 diabetes mellitus". 对“预测成人1型糖尿病患者严重糖尿病痛苦的机器学习方法”的评论。
IF 3 3区 医学
Journal of Diabetes Investigation Pub Date : 2026-07-01 Epub Date: 2026-05-09 DOI: 10.1111/jdi.70331
Yindan Song, Linwei Xia
{"title":"Comment on \"A machine learning approach to predicting severe diabetes distress in adults with type 1 diabetes mellitus\".","authors":"Yindan Song, Linwei Xia","doi":"10.1111/jdi.70331","DOIUrl":"10.1111/jdi.70331","url":null,"abstract":"","PeriodicalId":190,"journal":{"name":"Journal of Diabetes Investigation","volume":" ","pages":"1239"},"PeriodicalIF":3.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147863362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methodological considerations in interpreting circRNA profiles in diabetic retinopathy. 解释糖尿病视网膜病变中circRNA谱的方法学考虑。
IF 3 3区 医学
Journal of Diabetes Investigation Pub Date : 2026-07-01 Epub Date: 2026-05-09 DOI: 10.1111/jdi.70334
Yindan Song, Xujun He
{"title":"Methodological considerations in interpreting circRNA profiles in diabetic retinopathy.","authors":"Yindan Song, Xujun He","doi":"10.1111/jdi.70334","DOIUrl":"10.1111/jdi.70334","url":null,"abstract":"","PeriodicalId":190,"journal":{"name":"Journal of Diabetes Investigation","volume":" ","pages":"1240"},"PeriodicalIF":3.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147863344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor in response to "Association between thyroid dysfunction and cognitive impairment in type 2 Diabetes Mellitus: A cross-sectional study". 致编辑的回复“2型糖尿病患者甲状腺功能障碍与认知障碍之间的关系：一项横断面研究”。
IF 3 3区 医学
Journal of Diabetes Investigation Pub Date : 2026-07-01 Epub Date: 2026-05-11 DOI: 10.1111/jdi.70337
Ayesha Asghar, Hamza Mustafa
{"title":"Letter to the Editor in response to \"Association between thyroid dysfunction and cognitive impairment in type 2 Diabetes Mellitus: A cross-sectional study\".","authors":"Ayesha Asghar, Hamza Mustafa","doi":"10.1111/jdi.70337","DOIUrl":"10.1111/jdi.70337","url":null,"abstract":"","PeriodicalId":190,"journal":{"name":"Journal of Diabetes Investigation","volume":" ","pages":"1241-1242"},"PeriodicalIF":3.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147866200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with discrepancy between glycated hemoglobin and glucose management indicator. 糖化血红蛋白与血糖管理指标差异的相关因素。
IF 3 3区 医学
Journal of Diabetes Investigation Pub Date : 2026-06-01 Epub Date: 2026-04-07 DOI: 10.1111/jdi.70306
Xiaomeng Wang, Xiaosa Chi
{"title":"Factors associated with discrepancy between glycated hemoglobin and glucose management indicator.","authors":"Xiaomeng Wang, Xiaosa Chi","doi":"10.1111/jdi.70306","DOIUrl":"10.1111/jdi.70306","url":null,"abstract":"","PeriodicalId":190,"journal":{"name":"Journal of Diabetes Investigation","volume":" ","pages":"1082"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13238785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147626714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of biliary diseases in patients with type 2 diabetes or obesity treated with tirzepatide: A critical appraisal. 用替西肽治疗2型糖尿病或肥胖患者胆道疾病的风险：一项关键评估
IF 3 3区 医学
Journal of Diabetes Investigation Pub Date : 2026-06-01 Epub Date: 2026-03-31 DOI: 10.1111/jdi.70298
Salvatore Corrao
{"title":"Risk of biliary diseases in patients with type 2 diabetes or obesity treated with tirzepatide: A critical appraisal.","authors":"Salvatore Corrao","doi":"10.1111/jdi.70298","DOIUrl":"10.1111/jdi.70298","url":null,"abstract":"","PeriodicalId":190,"journal":{"name":"Journal of Diabetes Investigation","volume":" ","pages":"1080-1081"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13238931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147579970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on "Lower glycemic status was associated with pancreatic cancer risk in prediabetes". 对“低血糖状态与糖尿病前期胰腺癌风险相关”的评论。
IF 3 3区 医学
Journal of Diabetes Investigation Pub Date : 2026-06-01 Epub Date: 2026-03-23 DOI: 10.1111/jdi.70294
Shih-Wei Lai, Kuan-Fu Liao
{"title":"Comment on \"Lower glycemic status was associated with pancreatic cancer risk in prediabetes\".","authors":"Shih-Wei Lai, Kuan-Fu Liao","doi":"10.1111/jdi.70294","DOIUrl":"10.1111/jdi.70294","url":null,"abstract":"","PeriodicalId":190,"journal":{"name":"Journal of Diabetes Investigation","volume":" ","pages":"1079"},"PeriodicalIF":3.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13238908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147496992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to the letter to the editor regarding "Association between diabetic peripheral neuropathy and lower limb muscle strength in patients with type 2 diabetes mellitus: A systematic review and meta-analysis". 回复关于“糖尿病周围神经病变与2型糖尿病患者下肢肌肉力量的关系：系统回顾和荟萃分析”的致编辑的信。
IF 3 3区 医学
Journal of Diabetes Investigation Pub Date : 2026-05-01 Epub Date: 2026-02-26 DOI: 10.1111/jdi.70271
Yuki Nakashima, Shunsuke Taito, Yukio Mikami
{"title":"Response to the letter to the editor regarding \"Association between diabetic peripheral neuropathy and lower limb muscle strength in patients with type 2 diabetes mellitus: A systematic review and meta-analysis\".","authors":"Yuki Nakashima, Shunsuke Taito, Yukio Mikami","doi":"10.1111/jdi.70271","DOIUrl":"10.1111/jdi.70271","url":null,"abstract":"","PeriodicalId":190,"journal":{"name":"Journal of Diabetes Investigation","volume":" ","pages":"898"},"PeriodicalIF":3.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13137269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147288887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
USP18 mediates high glucose-induced cardiomyocyte injury by regulating the JAK/STAT signaling pathway through stabilizing FOXC2 expression. USP18通过稳定FOXC2表达，调控JAK/STAT信号通路，介导高糖诱导的心肌细胞损伤。
IF 3 3区 医学
Journal of Diabetes Investigation Pub Date : 2026-05-01 Epub Date: 2026-03-06 DOI: 10.1111/jdi.70210
Zhengrong Xu, Weidong Ren, Jun Gu, Wenjuan Deng, Lijuan Zuo
{"title":"USP18 mediates high glucose-induced cardiomyocyte injury by regulating the JAK/STAT signaling pathway through stabilizing FOXC2 expression.","authors":"Zhengrong Xu, Weidong Ren, Jun Gu, Wenjuan Deng, Lijuan Zuo","doi":"10.1111/jdi.70210","DOIUrl":"10.1111/jdi.70210","url":null,"abstract":"<p><strong>Background: </strong>Cardiomyopathy is one of the complications of diabetes, among which myocardial fibrosis is the most typical feature. Ubiquitin-specific peptidase 18 (USP18) is a deubiquitinating enzyme. Multiple studies suggest that it may have the potential to protect against myocardial injury under diabetes, but the specific mechanism remains unclear.</p><p><strong>Methods: </strong>The high glucose (HG) was used to treat neonatal mouse ventricular myocytes (NMVMs) to induce diabetic myocardial injury models, and gene expression was detected by quantitative reverse transcription polymerase chain reaction (RT-qPCR) and Western blot. The phenotypes of NMVMs were measured using cell counting kit-8 (CCK-8), the corresponding kits, flow cytometry, enzyme-linked immunosorbent assay (ELISA), and DCFH-DA probe. Besides, cell fibrosis was reflected by immunofluorescence (IF) and Western blot assay. Ubiquitination analysis and Cycloheximide (CHX) experiment were applied to assess protein ubiquitination and degradation, respectively.</p><p><strong>Results: </strong>USP18 was downregulated in HG-induced NMVMs, and USP18 overexpression promoted viability and inhibited apoptosis of NMVMs exposed to HG. Meanwhile, the inflammation, oxidative stress, and fibrosis of NMVMs impelled by HG were reversed after USP18 upregulation. Mechanically, USP18 stabilized forkhead box C2 (FOXC2) expression by reducing its ubiquitination to participate in regulating NMVM viability, apoptosis, inflammation, oxidative stress, and fibrosis via the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway.</p><p><strong>Conclusions: </strong>USP18 inhibits the ubiquitination of FOXC2 to stabilize its expression, thereby mediating HG-induced myocardial injury through the JAK/STAT pathway.</p>","PeriodicalId":190,"journal":{"name":"Journal of Diabetes Investigation","volume":" ","pages":"729-738"},"PeriodicalIF":3.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13137288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147369060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
β-cell recovery revisited: Is prediabetes remission driven by insulin sensitivity or β-cell function? β细胞恢复：糖尿病前期缓解是由胰岛素敏感性还是β细胞功能驱动的？
IF 3 3区 医学
Journal of Diabetes Investigation Pub Date : 2026-05-01 Epub Date: 2026-03-20 DOI: 10.1111/jdi.70292
Joonyub Lee, Kun-Ho Yoon
{"title":"β-cell recovery revisited: Is prediabetes remission driven by insulin sensitivity or β-cell function?","authors":"Joonyub Lee, Kun-Ho Yoon","doi":"10.1111/jdi.70292","DOIUrl":"10.1111/jdi.70292","url":null,"abstract":"","PeriodicalId":190,"journal":{"name":"Journal of Diabetes Investigation","volume":" ","pages":"716-718"},"PeriodicalIF":3.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13137268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147490270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on "The association between COVID-19 and incident gestational diabetes: A population-based case-control study of the National Health Insurance Research Database in Taiwan". 《新冠肺炎与妊娠期糖尿病的关系：台湾全民健康保险研究数据库的人群病例对照研究》
IF 3 3区 医学
Journal of Diabetes Investigation Pub Date : 2026-05-01 Epub Date: 2026-02-27 DOI: 10.1111/jdi.70272
Lidong Gao
{"title":"Comment on \"The association between COVID-19 and incident gestational diabetes: A population-based case-control study of the National Health Insurance Research Database in Taiwan\".","authors":"Lidong Gao","doi":"10.1111/jdi.70272","DOIUrl":"10.1111/jdi.70272","url":null,"abstract":"","PeriodicalId":190,"journal":{"name":"Journal of Diabetes Investigation","volume":" ","pages":"899-900"},"PeriodicalIF":3.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13137270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147300456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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